H. Derendorf

发表

Simultaneous measurement of cortisol in serum and saliva after different forms of cortisol administration.

S. Tunn, H. Möllmann, J. Barth, 1992, Clinical chemistry.

Pediatric Dosing and Body Size in Biotherapeutics

H. Derendorf, Rong Shi, 2010, Pharmaceutics.

Relevance of pharmacokinetics and pharmacodynamics of inhaled corticosteroids to asthma

H. Derendorf, R. Nave, A. Drollmann, 2006, European Respiratory Journal.

Characterizing the Effects of Caspofungin on Candida albicans, Candida parapsilosis, and Candida glabrata Isolates by Simultaneous Time-Kill and Postantifungal-Effect Experiments

H. Derendorf, C. Clancy, M. Nguyen, 2006, Antimicrobial Agents and Chemotherapy.

Impact of Ethnicity-Specific Hepatic Microsomal Scaling Factor, Liver Weight, and Cytochrome P450 (CYP) 1A2 Content on Physiologically Based Prediction of CYP1A2-Mediated Pharmacokinetics in Young and Elderly Chinese Adults

Guangji Wang, H. Derendorf, Q. Zheng, 2019, Clinical Pharmacokinetics.

Enhanced penetration of moxifloxacin into rat prostate tissue evidenced by microdialysis.

H. Derendorf, T. Dalla Costa, Felipe K. Hurtado, 2014, International journal of antimicrobial agents.

Population Pharmacokinetic Model of Human Insulin Following Different Routes of Administration

Hartmut Derendorf, Elizabeth Potocka, H. Derendorf, 2011, Journal of clinical pharmacology.

Population pharmacodynamic model of bronchodilator response to inhaled albuterol in children and adults with asthma.

Hartmut Derendorf, Rajanikanth Madabushi, J. Lima, 2008, Chest.

Proposal for a standardised identification of the mono‐exponential terminal phase for orally administered drugs

C. Kloft, H. Derendorf, Christian Scheerans, 2008, Biopharmaceutics & drug disposition.

The Lack of Effect of Aerobic Exercise Training on Propranolol Pharmacokinetics in Young and Elderly Adults

M. Pollock, D. Lowenthal, J. Graves, 1995, Journal of clinical pharmacology.

Application of Two-Point Assay of Digoxin Serum Concentration in Studying Population Pharmacokinetics in Egyptian Pediatric Patients with Heart Failure: Does It Make Sense?

H. Derendorf, R. Madabushi, E. Desoky, 2005, American journal of therapeutics.

A Markov Chain Model to Evaluate the Effect of CYP3A5 and ABCB1 Polymorphisms on Adverse Events Associated with Tacrolimus in Pediatric Renal Transplantation

H. Derendorf, S. Shilbayeh, D. Conrado, 2013, The AAPS Journal.

Pharmacokinetics of Methylprednisolone and Prednisolone After Single and Multiple Oral Administration

H. Möllmann, J. Barth, H. Derendorf, 1997, Journal of clinical pharmacology.

Dynamic Modeling of Cortisol Reduction after Inhaled Administration of Fluticasone Propionate

A Bye, H Derendorf, B. Meibohm, 1996, Journal of clinical pharmacology.

Pharmacokinetics of Triamcinolone Acetonide After Intravenous, Oral, and Inhaled Administration

H. Möllmann, J. Barth, H. Derendorf, 1995, Journal of clinical pharmacology.

Effects of fentanyl dose and exposure duration on the affective and somatic signs of fentanyl withdrawal in rats

M. Gold, H. Derendorf, A. Bruijnzeel, 2008, Neuropharmacology.

Pulmonary delivery of amikacin liposomes and acute liposome toxicity in the sheep

H. Schreier, A. Stecenko, H. Derendorf, 1992 .

Evolution of Pharmacokinetics and Pharmacokinetic/Dynamic Correlations during the 20th Century

J. Barrett, H. Derendorf, G. Hochhaus, 2000, Journal of clinical pharmacology.

When is protein binding important?

H. Derendorf, S. Schmidt, Jules Heuberger, 2013, Journal of pharmaceutical sciences.

Issues in Pharmacokinetics and Pharmacodynamics of Anti-Infective Agents: Distribution in Tissue

H. Derendorf, Markus Müller, Amparo dela Peña, 2004, Antimicrobial Agents and Chemotherapy.

Pharmacokinetic/Pharmacodynamic (PK/PD) Evaluation of a Once-Daily Treatment Using Ciprofloxacin in an Extended-Release Dosage Form*

E. Schuck, H. Derendorf, H. Stass, 2005, Infection.

Effect of reducing the paediatric stavudine dose by half: a physiologically-based pharmacokinetic model.

M. Cotton, H. Derendorf, S. Sy, 2015, International journal of antimicrobial agents.

Pharmacokinetic/Pharmacodynamic Consequences of Space Flight

H. Derendorf, 1994, Journal of clinical pharmacology.

Physiological, Pharmacokinetic, and Pharmacodynamic Changes in Space

E. Schuck, H. Derendorf, L. Putcha, 2004, Journal of clinical pharmacology.

Pharmacokinetic and Pharmacodynamic Changes in the Elderly

D. Lowenthal, H. Derendorf, A. Hämmerlein, 1998, Clinical pharmacokinetics.

Tobacco smoke exposure induces nicotine dependence in rats

M. Gold, H. Derendorf, J. R. Pauly, 2009, Psychopharmacology.

Pharmacokinetics and Pharmacodynamics of Biotech Drugs

B. Meibohm, H. Derendorf, 2006 .

Title : Drugs in Space : Pharmacokinetics and Pharmacodynamics in Astronauts Author names and affiliations :

H. Derendorf, C. Seubert, Yichao Yu, 2017 .

Tissue concentrations: do we ever learn?

O. Cars, W. Craig, P. Tulkens, 2007, The Journal of antimicrobial chemotherapy.

Microdialysis of Large Molecules.

S. Jadhav, H. Derendorf, Vipada Khaowroongrueng, 2016, Journal of pharmaceutical sciences.

In vitro microdialysis sampling of docetaxel.

Virna J. A. Schuck, H. Derendorf, Irene Rinas, 2004, Journal of pharmaceutical and biomedical analysis.

Relationship Between Serum and Free Interstitial Concentrations of Cefodizime and Cefpirome in Muscle and Subcutaneous Adipose Tissue of Healthy Volunteers Measured by Microdialysis

H. Eichler, A. Georgopoulos, H. Derendorf, 1997, Journal of clinical pharmacology.

Pharmacokinetics and pharmacodynamics of ponesimod, a selective S1P1 receptor modulator, in the first-in-human study.

H. Derendorf, H. Maatouk, A. Halabi, 2013, British journal of clinical pharmacology.

Pharmacokinetic modelling of serum and bronchial concentrations for clarithromycin and telithromycin, and site‐specific pharmacodynamic simulation for their dosages

H. Derendorf, K. Ikawa, N. Morikawa, 2014, Journal of clinical pharmacy and therapeutics.

Population Pharmacokinetics of Methotrexate in Egyptian Children with Lymphoblastic Leukemia

H. Derendorf, Rajendra P. Singh, E. S. Desoky, 2013 .

Basic Principles of Biopharmaceutics and Pharmacokinetics During Spaceflight

H. Derendorf, C. Seubert, Yichao Yu, 2018, Handbook of Space Pharmaceuticals.

In vitro pharmacodynamic models to determine the effect of antibacterial drugs.

C. Kloft, H. Derendorf, Christian Scheerans, 2010, The Journal of antimicrobial chemotherapy.

A mathematical model-based analysis of the time–kill kinetics of ceftazidime/avibactam against Pseudomonas aeruginosa

Virna J. A. Schuck, H. Derendorf, H. Xia, 2018, The Journal of antimicrobial chemotherapy.

Potentiation of ceftazidime by avibactam against &bgr;-lactam-resistant Pseudomonas aeruginosa in an in vitro infection model

Virna J. A. Schuck, C. Grunwitz, H. Derendorf, 2017, The Journal of antimicrobial chemotherapy.

Pharmacometrics in Bacterial Infections

H. Derendorf, S. Sy, 2014 .

PK/PD Approaches

H. Derendorf, W. Weber, Yichao Yu, 2011 .

PA-824 Exhibits Time-Dependent Activity in a Murine Model of Tuberculosis

H. Derendorf, J. Grosset, C. Peloquin, 2010, Antimicrobial Agents and Chemotherapy.

Handbook of Pharmacokinetic/Pharmacodynamic Correlation

H. Derendorf, G. Hochhaus, 1995 .

Pharmacokinetic-pharmacodynamic profile of systemic nitric oxide-synthase inhibition with L-NMMA in humans.

M. Wolzt, L. Schmetterer, H. Eichler, 1999, British journal of clinical pharmacology.

A combined in vivo pharmacokinetic-in vitro pharmacodynamic approach to simulate target site pharmacodynamics of antibiotics in humans.

H Derendorf, S. Hofmann, H. Eichler, 2000, The Journal of antimicrobial chemotherapy.

Application of pharmacokinetic/pharmacodynamic modelling and simulation for the prediction of target attainment of ceftobiprole against meticillin-resistant Staphylococcus aureus using minimum inhibitory concentration and time-kill curve based approaches.

H. Derendorf, K. Rand, S. Schmidt, 2014, International journal of antimicrobial agents.

Pharmacokinetic/pharmacodynamic modeling of in vitro activity of azithromycin against four different bacterial strains.

H. Derendorf, K. Rand, S. Schmidt, 2007, International journal of antimicrobial agents.

Pharmacokinetic-pharmacodynamic modelling of the in vitro antiinfective effect of piperacillin-tazobactam combinations.

H. Derendorf, T. Dalla Costa, K. Rand, 1997, International journal of clinical pharmacology and therapeutics.

Development and Validation of a Sensitive UFLC–MS/MS Method for Quantification of Quercitrin in Plasma: Application to a Tissue Distribution Study

H. Derendorf, F. Barreto, J. Bastos, 2019, ACS Omega.

Bioavailability and disposition of azelastine and fluticasone propionate when delivered by MP29-02, a novel aqueous nasal spray.

J. Bousquet, U. Munzel, H. Derendorf, 2012, British journal of clinical pharmacology.

Computer-modulated Patient-controlled Analgesia: Preliminary Evaluation of a Prototype

H. Derendorf, J. van der Aa, N. Gravenstein, 1993, Regional Anesthesia & Pain Medicine.

Cavitary Penetration of Levofloxacin among Patients with Multidrug-Resistant Tuberculosis

J. Guarner, H. Derendorf, A. Barth, 2015, Antimicrobial Agents and Chemotherapy.

Clinical Pharmacokinetics and Pharmacodynamics of Tigecycline

H. Derendorf, K. Rand, S. Schmidt, 2009, Clinical pharmacokinetics.

Professor Yuichi Sugiyama: A Brilliant, Creative, Amicable, Charming, and Humorous Pharmaceutical Scientist.

H. Kusuhara, Shiew-Mei Huang, R. Obach, 2017, Journal of pharmaceutical sciences.

Population Kinetics, Efficacy, and Safety of Dichloroacetate for Lactic Acidosis Due to Severe Malaria in Children

A. Hutson, D. Ansong, T. Agbenyega, 2003, Journal of clinical pharmacology.

A Novel Breath Test to Directly Measure Use of Vaginal Gel and Condoms

K. Smith-McCune, D. Dennis, H. Derendorf, 2013, AIDS and Behavior.

AAPS-FDA workshop white paper: Microdialysis principles, application, and regulatory perspectives report from the Joint AAPS-FDA Workshop, November 4–5, 2005, Nashville, TN

U. Ungerstedt, V. Shah, C. Lunte, 2007, The AAPS Journal.

Microdialysis

H. Derendorf, Markus Müller, C. Joukhadar, 2002, BMJ : British Medical Journal.

Inhaled corticosteroids: past lessons and future issues.

G. Colice, S. Szefler, R. Dluhy, 2003, The Journal of allergy and clinical immunology.

Pharmacokinetics I: PK-PD approaches - antibiotic drug development

H. Derendorf, S. Sabarinath, Rajendra P. Singh, 2010 .

PK-PD modelling of the effect of cefaclor on four different bacterial strains.

H. Derendorf, K. Rand, Markus Müller, 2004, International journal of antimicrobial agents.

Prediction of in vivo and in vitro infection model results using a semimechanistic model of avibactam and aztreonam combination against multidrug resistant organisms

H. Derendorf, H. Xia, L. Zhuang, 2017, CPT: pharmacometrics & systems pharmacology.

Dose optimization of moxifloxacin and linezolid against tuberculosis using mathematical modeling and simulation.

G. Drusano, H. Derendorf, K. Rand, 2019, International journal of antimicrobial agents.

Ertapenem in critically ill patients with early-onset ventilator-associated pneumonia: pharmacokinetics with special consideration of free-drug concentration.

T. Welte, H. Derendorf, Vipul Kumar, 2006, The Journal of antimicrobial chemotherapy.

Penetration of Ertapenem Into Different Pulmonary Compartments of Patients Undergoing Lung Surgery

T. Welte, H. Derendorf, R. Mundkowski, 2005, Journal of clinical pharmacology.

Comparison of the pharmacokinetic properties of vancomycin, linezolid, tigecyclin, and daptomycin

H. Derendorf, K. S. Estes, 2010, European journal of medical research.

Single‐ and Multiple‐Dose Pharmacokinetics of Oral Creatine

A. Persky, M. Grant, H. Derendorf, 2003, Journal of clinical pharmacology.

Pharmacokinetic interaction between endogenous cortisol and exogenous corticosteroids.

H. Möllmann, J. Barth, H. Derendorf, 1995, Die Pharmazie.

Pharmacokinetics and Bioavailability of Quercetin Glycosides in Humans

G. Jacobasch, H. Derendorf, M. Veit, 2001, Journal of clinical pharmacology.

Ciclesonide: A Pro-Soft Drug Approach for Mitigation of Side Effects of Inhaled Corticosteroids.

H. Derendorf, R. S. Singh, J. K. Mukker, 2016, Journal of pharmaceutical sciences.

The systemic safety of inhaled corticosteroid therapy: a focus on ciclesonide.

E. Meltzer, H. Derendorf, 2006, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Enzyme‐ and transporter‐mediated beverage–drug interactions: An update on fruit juices and green tea

Hartmut Derendorf, H. Derendorf, R. Frye, 2015, Journal of clinical pharmacology.

AAPS‐FDA Workshop White Paper: Microdialysis Principles, Application, and Regulatory Perspectives

U. Ungerstedt, V. Shah, C. Lunte, 2007 .

Effect of fat distribution on the pharmacokinetics of cortisol in obesity.

A. Moretti, H. Derendorf, D. Giannella‐Neto, 1998, International journal of clinical pharmacology and therapeutics.

Drug Metabolism Human Liver Aldehyde Oxidase: Inhibition by 239 Drugs 7

R. Obach, M. Farré, S. Szefler, 2004 .

Evaluation of the effects of Maytenus ilicifolia on the activities of cytochrome P450 3A and P-glycoprotein.

H. Derendorf, J. Duarte-Almeida, Sara Batista do Nascimento, 2020, Current drug metabolism.

Hyperforin in St. John’s wort drug interactions

H. Derendorf, V. Butterweck, R. Madabushi, 2006, European Journal of Clinical Pharmacology.

Pharmacokinetics and pharmacodynamics of glucocorticoid suspensions after intra‐articular administration

H. Möllmann, H. Derendorf, D. Haack, 1986, Clinical pharmacology and therapeutics.

Characterization of intestinal absorption of C-glycoside flavonoid vicenin-2 from Lychnophora ericoides leafs in rats by nonlinear mixed effects modeling

N. Lopes, H. Derendorf, G. Buqui, 2015 .

KA 672‐HCl, a Neuronal Activator Against Dementia: Tolerability, Safety, and Preliminary Pharmacokinetics after Single and Multiple Oral Doses in Healthy Male and Female Volunteers

R. Hoerr, H. Derendorf, H. Sourgens, 1998, Journal of clinical pharmacology.

Clinical PK/PD modelling as a tool in drug development of corticosteroids.

B. Meibohm, H. Möllmann, J. Barth, 1997, International journal of clinical pharmacology and therapeutics.

Once-daily tobramycin in cystic fibrosis: better for clinical outcome than thrice-daily tobramycin but more resistance development?

T. Welte, H. Derendorf, Vipul Kumar, 2006, The Journal of antimicrobial chemotherapy.

PK/PD Approaches

H. Derendorf, W. Weber, Yichao Yu, 2020, Drug Discovery and Evaluation: Methods in Clinical Pharmacology.

Systemic bioavailability of inhaled steroids: the importance of appropriate and comparable methodology.

H. Derendorf, P. Daley-Yates, J. Efthimiou, 2001, The European respiratory journal.

Role of pharmacokinetics in establishing bioequivalence for orally inhaled drug products: workshop summary report.

A. Fuglsang, S. Lee, H. Derendorf, 2011, Journal of aerosol medicine and pulmonary drug delivery.

Comparative pharmacology, bioavailability, pharmacokinetics, and pharmacodynamics of inhaled glucocorticosteroids.

H. Derendorf, G. Hochhaus, M. Hübner, 2005, Immunology and allergy clinics of North America.

Risk‐Benefit Value of Inhaled Glucocorticoids: A Pharmacokinetic/ Pharmacodynamic Perspective

S. Szefler, H. Derendorf, R. Nave, 2004, Journal of clinical pharmacology.

Pharmacokinetic and Pharmacodynamic Evaluation of Triamcinolone Acetonide After Intravenous, Oral, and Inhaled Administration

H. Möllmann, J. Barth, H. Derendorf, 1995, Journal of clinical pharmacology.

Dependency of Cortisol Suppression on the Administration Time of Inhaled Corticosteroids

B. Meibohm, H. Möllmann, J. Barth, 1997, Journal of clinical pharmacology.

Local Treatment of Respiratory Infections with Antibiotics

H. Derendorf, S. A. Stout, 1987, Drug intelligence & clinical pharmacy.

ciclesonide in the Management of Asthma

H. Derendorf, D. Gonzalez, 2009 .

Single‐Dose and Steady‐State Pharmacokinetic and Pharmacodynamic Evaluation of Therapeutically Clinically Equivalent Doses of Inhaled Fluticasone Propionate and Budesonide, Given as Diskus® or Turbohaler® Dry‐Powder Inhalers to Healthy Subjects

H. Möllmann, J. Barth, H. Derendorf, 2001, Journal of clinical pharmacology.

A sensitive LC-MS/MS method for the quantification of fluticasone propionate in human plasma.

H. Möllmann, H. Derendorf, G. Hochhaus, 2000, Journal of pharmaceutical and biomedical analysis.

Pharmacokinetic and pharmacodynamic properties of inhaled corticosteroids in relation to efficacy and safety.

H. Derendorf, 1997, Respiratory medicine.

Pharmacokinetic and pharmacodynamic implications in inhalable antimicrobial therapy.

H. Derendorf, R. S. Singh, J. Mukker, 2015, Advanced drug delivery reviews.

Intranasal Loteprednol Etabonate in Healthy Male Subjects: Pharmacokinetics and Effects on Endogenous Cortisol

H. Derendorf, R. Hermann, G. Hochhaus, 2004, Journal of clinical pharmacology.

Clinical Microdialysis in Skin and Soft Tissues: An Update

H. Derendorf, K. Rand, S. Schmidt, 2008, Journal of clinical pharmacology.

Pharmacokinetics and pharmacodynamics of inhaled corticosteroids.

B. Meibohm, H. Möllmann, J. Barth, 1998, The Journal of allergy and clinical immunology.

Pharmacokinetic/Pharmacodynamic Aspects of Aerosol Therapy using Glucocorticoids as a Model

H. Möllmann, H. Derendorf, R. Gonzalez-Rothi, 1997, Journal of clinical pharmacology.

Receptor‐Based Pharmacokinetic‐Pharmacodynamic Analysis of Corticosteroids

S. Tunn, J. Barth, H. Derendorf, 1993, Journal of clinical pharmacology.

Population Pharmacokinetics and Pharmacodynamics of Inhaled Ciclesonide and Fluticasone Propionate in Patients With Persistent Asthma

H. Derendorf, E. Derom, G. Lahu, 2010, Journal of clinical pharmacology.

Ertapenem: the new carbapenem 5 years after first FDA licensing for clinical practice

T. Welte, H. Derendorf, O. Burkhardt, 2007, Expert opinion on pharmacotherapy.

Mathematical modeling of cortisol circadian rhythm and cortisol suppression

H. Derendorf, S. Rohatagi, A. Bye, 1996 .

Evaluation of pulmonary absorption using pharmacokinetic methods.

H. Möllmann, H. Derendorf, G. Hochhaus, 2001, Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine.

Measuring drug distribution in the critically ill patient.

H. Derendorf, A. Deitchman, 2014, Advanced drug delivery reviews.

Kinetics of methylprednisolone and its hemisuccinate ester

H. Möllmann, H. Derendorf, P. Rohdewald, 1985, Clinical pharmacology and therapeutics.

Population Pharmacokinetic Modeling of the Unbound Levofloxacin Concentrations in Rat Plasma and Prostate Tissue Measured by Microdialysis

H. Derendorf, T. Dalla Costa, F. K. Hurtado, 2013, Antimicrobial Agents and Chemotherapy.

Pharmacokinetic/Pharmacodynamic Modeling of Total Lymphocytes and Selected Subtypes After Oral Budesonide

H. Derendorf, M. Krieg, J. Stark, 2006, Journal of Pharmacokinetics and Pharmacodynamics.

Agents : Kill Curves versus MIC Pharmacodynamics of Anti-Infective Issues in Pharmacokinetics and

H. Derendorf, Markus Mueller, A. Peña, 2004 .

Population pharmacokinetics of cilengitide in adult and pediatric cancer patients from a nonlinear mixed‐effects analysis

M. Campioni, H. Derendorf, A. Kovar, 2014, Journal of clinical pharmacology.

Clinical Microdialysis in Skin and Soft Tissues

H. Derendorf, M. Sahre, R. Naik, 2011 .

Thromboelastographic and pharmacokinetic profiles of micro‐ and macro‐emulsions of propofol in swine

D. Shah, D. Dennis, H. Derendorf, 2010, Biopharmaceutics & drug disposition.

Suppression of ciprofloxacin-induced resistant Pseudomonas aeruginosa in a dynamic kill curve system.

Judith A. Johnson, H. Derendorf, K. Rand, 2011, International journal of antimicrobial agents.

Fundamentals of antimicrobial pharmacokinetics and pharmacodynamics

A. Vinks, H. Derendorf, J. Mouton, 2014 .

Pharmacokinetics and pharmacodynamics of ponesimod, a selective S1P1 receptor modulator, in the firstinhuman study

H. Derendorf, H. Maatouk, A. Halabi, 2013 .

Pharmacokinetic-Pharmacodynamic Modeling of the Antibiotic Effect of Piperacillin in Vitro

H. Derendorf, K. Rand, T. D. Costa, 2004, Pharmaceutical Research.

Enhanced in vitro activity of tigecycline in the presence of chelating agents.

H. Derendorf, K. Rand, R. S. Singh, 2018, International journal of antimicrobial agents.

Population Pharmacokinetics of Eniporide and Its Metabolite in Healthy Subjects and Patients With Acute Myocardial Infarction

T. Machnig, H. Derendorf, A. Kovar, 2005, Journal of clinical pharmacology.

Pharmacokinetics and bioavailability of herbal medicinal products.

H. Derendorf, M. Veit, V. Bhattaram, 2002, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Systemic Availability and Pharmacokinetics of Thymol in Humans

H. Derendorf, B. Brinkhaus, M. Veit, 2002 .

Pharmacokinetics of Intravenous Immunoglobulin (Gammagard) in Bone Marrow Transplant Patients

J. Graham-Pole, H. Derendorf, K. Rand, 1991, Journal of clinical pharmacology.

Estimation of Intracellular Concentration of Stavudine Triphosphate in HIV-Infected Children Given a Reduced Dose of 0.5 Milligrams per Kilogram Twice Daily

M. Cotton, H. Derendorf, S. Sy, 2013, Antimicrobial Agents and Chemotherapy.

Pharmacokinetic and pharmacodynamic evaluation of fluticasone propionate after inhaled administration

B. Meibohm, H. Möllmann, J. Barth, 1998, European Journal of Clinical Pharmacology.

Population Pharmacokinetics of Intramuscular Quinine in Children with Severe Malaria

D. Ansong, T. Agbenyega, S. Krishna, 2001, Antimicrobial Agents and Chemotherapy.

Current concepts in pharmacokinetics and their implications for clinical medicine.

H. Derendorf, G. Hochhaus, M. Müller, 2001, Wiener klinische Wochenschrift.

Pharmacokinetic and Pharmacodynamic Properties of Inhaled Ciclesonide

H. Derendorf, 2007, Journal of clinical pharmacology.

The Effect of Protein Binding on Adrenal Suppression Potential of Inhaled Corticosteroids

H. Derendorf, G. Hochhaus, 2006 .

PK/PD of inhaled corticosteroids: The risk/benefit of inhaled ciclesonide

H. Derendorf, R. Nave, S. Rohatagi, 2003 .

Desensitization of brain opiate receptor mechanisms by gonadal steroid treatments that stimulate luteinizing hormone secretion.

J. Simpkins, H. Derendorf, L. Berglund, 1988, Endocrinology.

HPLC determination of glucocorticoid alcohols, their phosphates and hydrocortisone in aqueous solutions and biological fluids.

H. Möllmann, H. Derendorf, G. Hochhaus, 1986, Journal of pharmaceutical and biomedical analysis.

The Significance of Optimized Formulation for Dipyridamole in Stroke Risk Reduction

H. Derendorf, K. S. Estes, 2007 .

Influence of plasma expansion on plasma protein binding of ketorolac.

H. Derendorf, D. Gravenstein, A. J. Koska, 1998, Journal of clinical anesthesia.

Interpretation of absorption rate data for inhaled fluticasone propionate obtained in compartmental pharmacokinetic modeling.

H. Möllmann, J. Barth, H. Derendorf, 2005, International journal of clinical pharmacology and therapeutics.

Pharmacokinetic/Pharmacodynamic Profile of Posaconazole

H. Derendorf, U. Theuretzbacher, C. Clancy, 2010, Clinical pharmacokinetics.

Pharmacokinetics and pharmacodynamics in antibiotic dose optimization

H. Derendorf, S. Sy, L. Zhuang, 2016, Expert opinion on drug metabolism & toxicology.

Pharmacokinetic and Pharmacodynamic Characterization of Tetrahydrocannabinol-Induced Cannabinoid Dependence After Chronic Passive Cannabis Smoke Exposure in Rats.

M. Febo, B. Setlow, Shannon C. Wall, 2019, Cannabis and cannabinoid research.

Pharmacokinetic/Pharmacodynamic Evaluation of Deflazacort in Comparison to Methylprednisolone and Prednisolone

H. Möllmann, J. Barth, H. Derendorf, 1995, Pharmaceutical Research.

Comparative Pharmacokinetics of Methylprednisolone Phosphate and Hemisuccinate in High Doses

H. Möllmann, J. Barth, H. Derendorf, 1988, Pharmaceutical Research.

Corticosteroid pharmacokinetic/pharmacodynamic parameters and their relationship to safety and efficacy.

H. Derendorf, 2005, Allergy and asthma proceedings.

Pharmacodynamic activity of the lantibiotic MU1140.

H. Derendorf, J. Hillman, Oliver G Ghobrial, 2009, International journal of antimicrobial agents.

Pharmacokinetics and Determination of Tumor Interstitial Distribution of a Therapeutic Monoclonal Antibody Using Large-Pore Microdialysis.

S. Jadhav, Muzeeb Syed, H. Derendorf, 2021, Journal of pharmaceutical sciences.

Pharmacokinetic/Pharmacodynamic Profile of Voriconazole

H. Derendorf, U. Theuretzbacher, F. Ihle, 2006, Clinical pharmacokinetics.

Pharmacokinetics of piperacillin-tazobactam: intermittent dosing versus continuous infusion.

T. Sauerbruch, H. Derendorf, C. Buck, 2005, International journal of antimicrobial agents.

The clinical pharmacology of fluticasone propionate

B. Meibohm, H. Möllmann, H. Derendorf, 1998 .

Pharmacokinetics and Oral Bioavailability of Hydrocortisone

S. Tunn, H. Möllmann, J. Barth, 1991, Journal of clinical pharmacology.

Tobacco smoke exposure enhances reward sensitivity in male and female rats

Adriaan W. Bruijnzeel, H. Derendorf, H. Chandasana, 2021, Psychopharmacology.

Simultaneous quantification of cannabinoids tetrahydrocannabinol, cannabidiol and CB1 receptor antagonist in rat plasma: An application to characterize pharmacokinetics after passive cannabis smoke inhalation and co‐administration of rimonabant

M. Febo, B. Setlow, Adriaan W. Bruijnzeel, 2018, Journal of Pharmaceutical and Biomedical Analysis.

Simulation-based sodium thiosulfate dosing strategies for the treatment of calciphylaxis.

H. Derendorf, E. Ross, Rajendra P. Singh, 2011, Clinical journal of the American Society of Nephrology : CJASN.

Pharmacokinetic properties of beta-lactamase inhibitors.

H. Derendorf, A. de la Peña, 1999, International journal of clinical pharmacology and therapeutics.

Pharmacokinetics of iron(III)-hydroxide sucrose complex after a single intravenous dose in healthy volunteers.

P. Geisser, H. Derendorf, T. Salmonson, 1996, Arzneimittel-Forschung.

Tissue Distribution of a Therapeutic Monoclonal Antibody Determined by Large Pore Microdialysis.

S. Jadhav, H. Derendorf, Michael B. Otteneder, 2017, Journal of pharmaceutical sciences.

Pharmacokinetic Evaluation of Avicularin Using a Model-Based Development Approach

N. Lopes, H. Derendorf, G. Buqui, 2015, Planta Medica.

Pharmacokinetics of Modified‐Release Prednisone Tablets in Healthy Subjects and Patients With Rheumatoid Arthritis

J. Kirwan, H. Derendorf, Lynsey L Clarke, 2013, Journal of clinical pharmacology.

Relationship between saliva levels of metamizol metabolites, bioavailability and analgesic efficacy.

H. Derendorf, P. Rohdewald, G. Drehsen, 1983, Arzneimittel-Forschung.

Population Pharmacokinetics of Digoxin in Egyptian Pediatric Patients: Impact of One Data Point Utilization

H. Derendorf, E. E. El Desoky, N. Nagaraja, 2002, American journal of therapeutics.

Population pharmacokinetics of steady‐state carbamazepine in Egyptian epilepsy patients

H. Derendorf, M. Bewernitz, S. Sabarinath, 2012, Journal of clinical pharmacy and therapeutics.

A review of the effects of chronic exercise and physical fitness level on resting pharmacokinetics.

A. Persky, H. Derendorf, N. Eddington, 2003, International journal of clinical pharmacology and therapeutics.

The effect of critical illness on drug distribution.

H. Derendorf, U. Theuretzbacher, D. Conrado, 2011, Current pharmaceutical biotechnology.

Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs: an update.

O. Cars, G. Drusano, H. Derendorf, 2005, The Journal of antimicrobial chemotherapy.

Pharmacokinetics of amikacin in critically ill neonatal foals treated for presumed or confirmed sepsis.

J. D. Robinson, H. Derendorf, M. Brown, 1990, Equine veterinary journal.

Pharmacokinetics of prednisolone after high doses of prednisolone hemisuccinate.

H. Möllmann, J. Barth, H. Derendorf, 1985, Biopharmaceutics & drug disposition.

Model‐Informed Drug Development for Anti‐Infectives: State of the Art and Future

E. Mills, C. Rayner, Virna J. A. Schuck, 2021, Clinical pharmacology and therapeutics.

Pharmacokinetic/pharmacodynamic modelling and in vitro simulation of dynamic voriconazole-Candida interactions.

L. Zhong, H. Derendorf, S. Schmidt, 2009, International Journal of Antimicrobial Agents.

A pharmacokinetic/pharmacodynamic mathematical model accurately describes the activity of voriconazole against Candida spp. in vitro.

L. Zhong, H. Derendorf, S. Schmidt, 2008, International journal of antimicrobial agents.

Changes in cortical evoked potentials as correlates of the efficacy of weak analgesics

C. E. Elger, C. Elger, H. Derendorf, 1982, Pain.

Comparison of skin permeability for three diclofenac topical formulations: an in vitro study.

H. Derendorf, D. Gonzalez, E. Folzer, 2014, Die Pharmazie.

Development and Validation of an HPLC Method for Oxytocin in Ringer's Lactate and its Application in Stability Analysis

H. Derendorf, R. Hatton, Vipul Kumar, 2006 .

Pharmacokinetic-Pharmacodynamic Modeling of the In Vitro Activities of Oxazolidinone Antimicrobial Agents against Methicillin-Resistant Staphylococcus aureus

H. Derendorf, S. Schmidt, S. Sabarinath, 2009, Antimicrobial Agents and Chemotherapy.

The use of 2-hydroxypropyl-β-cyclodextrin as a vehicle for intravenous administration of dexamethasone in dogs

N. Bodor, M. Brewster, H. Derendorf, 1990 .

AAPS-FDA Workshop White Paper: Microdialysis Principles, Application and Regulatory Perspectives

Eva Benfeldt, Vinod P. Shah, Hartmut Derendorf, 2006, Pharmaceutical Research.

Development of apratoxin S10 (Apra S10) as an anti-pancreatic cancer agent and its preliminary evaluation in an orthotopic patient-derived xenograft (PDX) model

H. Derendorf, J. Trevino, Qi-Yin Chen, 2018, Investigational New Drugs.

Pharmacokinetics of dexamethasone and its phosphate ester.

H. Möllmann, J. Barth, H. Derendorf, 1987, Biopharmaceutics & drug disposition.

Issues in Pharmacokinetics and Pharmacodynamics of Anti-Infective Agents: Kill Curves versus MIC

Hartmut Derendorf, H. Derendorf, Markus Mueller, 2004, Antimicrobial Agents and Chemotherapy.

Relevance of liver failure for anti-infective agents: from pharmacokinetic alterations to dosage adjustments

H. Derendorf, D. Gonzalez, Fiona V. Büdingen, 2014, Therapeutic advances in infectious disease.

Utility of Microdialysis in Infectious Disease Drug Development and Dose Optimization

S. Jadhav, H. Derendorf, M. T. Heinrichs, 2017, The AAPS Journal.

Determination of Dermal Pharmacokinetics by Microdialysis Sampling in Rats

H. Derendorf, Alexander Voelkner, N. M. F. Voelkner, 2019, Current protocols in pharmacology.

Dermal pharmacokinetics of pyrazinamide determined by microdialysis sampling in rats.

H. Derendorf, S. Sy, Johanna Weitzel, 2017, International journal of antimicrobial agents.

Class-dependent relevance of tissue distribution in the interpretation of anti-infective pharmacokinetic/pharmacodynamic indices.

H. Derendorf, F. Scaglione, A. Barbour, 2010, International journal of antimicrobial agents.

Pharmacokinetics I: PK-PD Approach, the Case of Antibiotic Drug Development

H. Derendorf, S. Sy, 2016 .

Pharmacodynamic In Vitro Models to Determine the Effect of Antibiotics

C. Kloft, H. Derendorf, A. Barth, 2014 .

Antimicrobial tissue concentrations.

H. Derendorf, Ping Liu, 2003, Infectious disease clinics of North America.

Gender differences in pharmacokinetics and pharmacodynamics.

H Derendorf, B. Meibohm, H. Derendorf, 1999, International journal of clinical pharmacology and therapeutics.

Pharmacokinetics of Dichloroacetate in Adult Patients with Lactic Acidosis

S. Curry, P. Stacpoole, E. Wright, 1997, Journal of clinical pharmacology.

Significance of protein binding in pharmacokinetics and pharmacodynamics.

Stephan Schmidt, Hartmut Derendorf, H. Derendorf, 2010, Journal of pharmaceutical sciences.

Methodologies for Protein Binding Determination in Anti-infective Agents

H. Derendorf, R. S. Singh, J. Mukker, 2016 .

Protein Binding: Do We Ever Learn?

O. Cars, W. Craig, M. Zeitlinger, 2011, Antimicrobial Agents and Chemotherapy.

MINIREVIEW Protein Binding: Do We Ever Learn?

O. Cars, W. Craig, M. Zeitlinger, 2011 .

Effect of Protein Binding on the Pharmacological Activity of Highly Bound Antibiotics

Stephan Schmidt, Hartmut Derendorf, Martin Brunner, 2008, Antimicrobial Agents and Chemotherapy.

Rational dosing of antibiotics: the use of plasma concentrations versus tissue concentrations.

H. Derendorf, Markus Müller, Ping Liu, 2002, International journal of antimicrobial agents.

Population Pharmacokinetic/ Pharmacodynamic Modeling of Cetrorelix, a Novel LH-RH Antagonist, and Testosterone in Rats and Dogs

H. Derendorf, N. Nagaraja, M. Schwahn, 2000, Pharmaceutical Research.

Microdialysis in peripheral tissues.

H Derendorf, H. Derendorf, A de la Peña, 2000, Advanced drug delivery reviews.

Penetration of Cefaclor Into the Interstitial Space Fluid of Skeletal Muscle and Lung Tissue in Rats

H. Derendorf, T. Dalla Costa, Markus Müller, 2001, Pharmaceutical Research.

Microdialysis sampling to monitor target-site vancomycin concentrations in septic infants - a feasible way to close the knowledge gap.

C. Kloft, M. Zeitlinger, H. Derendorf, 2021, International journal of antimicrobial agents.

Determination of atypical nonlinear plasma−protein-binding behavior of tigecycline using an in vitro microdialysis technique.

H. Derendorf, J. Mukker, R. Singh, 2014, Journal of pharmaceutical sciences.

Clinical Pharmacokinetics and Pharmacodynamics of Ceftazidime–Avibactam Combination: A Model-Informed Strategy for its Clinical Development

H. Derendorf, S. Sy, Serubbabel Sy, 2018, Clinical Pharmacokinetics.

Experimental design and modelling approach to evaluate efficacy of β-lactam/β-lactamase inhibitor combinations.

H. Derendorf, S. Sy, 2017, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Research priorities towards precision antibiotic therapy to improve patient care.

C. Landersdorfer, Jian Li, S. Wicha, 2022, The Lancet. Microbe.

Moxifloxacin target site concentrations in patients with pulmonary TB utilizing microdialysis: a clinical pharmacokinetic study

J. Guarner, Adam Bernheim, B. Little, 2018, The Journal of antimicrobial chemotherapy.

Importance of Relating Efficacy Measures to Unbound Drug Concentrations for Anti-Infective Agents

H. Derendorf, S. Schmidt, D. Gonzalez, 2013, Clinical Microbiology Reviews.

Population Pharmacokinetic Modeling of the Unbound Levofloxacin Concentrations in Plasma 1

Felipe K. Hurtado, Benjamin Weber, Hartmut Derendorf, 2013 .

Microdialysis in Antibiotic Research

W. Couet, M. Zeitlinger, H. Derendorf, 2013 .

Soft tissue penetration of cefuroxime determined by clinical microdialysis in morbidly obese patients undergoing abdominal surgery.

W. R. Rout, H. Derendorf, K. Ben-David, 2009, International journal of antimicrobial agents.

Ceftobiprole: a novel cephalosporin with activity against Gram-positive and Gram-negative pathogens, including methicillin-resistant Staphylococcus aureus (MRSA).

H. Derendorf, K. Rand, S. Schmidt, 2009, International journal of antimicrobial agents.

Moxifloxacin distribution in the interstitial space of infected decubitus ulcer tissue of patients with spinal cord injury measured by in vivo microdialysis

J. Barth, H. Derendorf, Vipul Kumar, 2006, Scandinavian journal of infectious diseases.

Effect of Simulated Microgravity on the Disposition and Tissue Penetration of Ciprofloxacin in Healthy Volunteers

Hartmut Derendorf, Maria Grant, M. Grant, 2005, Journal of clinical pharmacology.

Tissue penetration of cefpodoxime into the skeletal muscle and lung in rats.

H. Derendorf, Ping Liu, A. Webb, 2005, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Tissue Penetration of Cefpodoxime and Cefixime in Healthy Subjects

M. Grant, H. Derendorf, Markus Müller, 2005, Journal of clinical pharmacology.

Interstitial tissue concentrations of cefpodoxime.

M. Grant, H. Derendorf, Markus Müller, 2002, The Journal of antimicrobial chemotherapy.

Comparative Target Site Pharmacokinetics of Immediate‐ and Modified‐Release Formulations of Cefaclor in Humans

H. Eichler, M. Brunner, H. Derendorf, 2002, Journal of clinical pharmacology.

Pharmacokinetic evaluation of -lactam antibiotics

H. Derendorf, 1989 .

Pharmacokinetic evaluation of beta-lactam antibiotics.

H. Derendorf, 1989, The Journal of antimicrobial chemotherapy.

Pharmacokinetic profile of cefaclor.

H. Derendorf, H. Sourgens, H. Schifferer, 1997, International journal of clinical pharmacology and therapeutics.

Clinical Pharmacokinetics of Meropenem and Biapenem in Bile and Dosing Considerations for Biliary Tract Infections Based on Site-Specific Pharmacodynamic Target Attainment

H. Derendorf, H. Ohge, Y. Murakami, 2011, Antimicrobial Agents and Chemotherapy.

Pharmacokinetics and pharmacodynamics of enantiomers of ibuprofen and flurbiprofen after oral administration.

H Derendorf, H. Derendorf, B. L. Grundy, 1997, International journal of clinical pharmacology and therapeutics.

Pharmacokinetic/ pharmacodynamic evaluation of anti-infective agents

Hartmut Derendorf, E. Schuck, H. Derendorf, 2005, Expert review of anti-infective therapy.

Microdialysis of triamcinolone acetonide in rat muscle.

H. Derendorf, N. Nagaraja, A. Webb, 2003, Journal of pharmaceutical sciences.

Excessive lysosomal ion-trapping of hydroxychloroquine and azithromycin

H. Derendorf, 2020, International Journal of Antimicrobial Agents.

A Reversed Phase Liquid Chromatographic Method for the Determination of Codeine in Biological Fluids with Applications

H. Derendorf, S. Mohammed, M. Butschkau, 1993 .

Pharmacokinetics of para-Aminosalicylic Acid in HIV-Uninfected and HIV-Coinfected Tuberculosis Patients Receiving Antiretroviral Therapy, Managed for Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis

A. Diacon, H. Derendorf, P. Donald, 2014, Antimicrobial Agents and Chemotherapy.

Gentamicin dosing strategy in patients with end-stage renal disease receiving haemodialysis: evaluation using a semi-mechanistic pharmacokinetic/pharmacodynamic model.

H. Derendorf, H. Xia, S. Sy, 2016, The Journal of antimicrobial chemotherapy.

Microdialysis as a tool in local pharmacodynamics

Hartmut Derendorf, Li Zhong, Joanna Peris, 2006, The AAPS Journal.

Quantitative Estimation of Plasma Free Drug Fraction in Patients With Varying Degrees of Hepatic Impairment: A Methodological Evaluation.

H. Derendorf, Q. Zheng, Guo-Fu Li, 2018, Journal of pharmaceutical sciences.

Differences in Drug Pharmacokinetics Between East Asians and Caucasians and the Role of Genetic Polymorphisms

Julie A. Johnson, H. Derendorf, Kiman Kim, 2004, Journal of clinical pharmacology.

Variability in response to cardiovascular drugs.

U. Klotz, H. Derendorf, E. E. El Desoky, 2006, Current clinical pharmacology.

Erythrocyte binding of cephalosporins

H. Derendorf, 1987, The Journal of pharmacy and pharmacology.

Simultaneous Retrodialysis by Calibrator for Rapid In Vivo Recovery Determination in Target Site Microdialysis.

H. Derendorf, C. Seubert, Yichao Yu, 2018, Journal of pharmaceutical sciences.

Extended Stability of Oxytocin in Ringer's Lactate Solution at 4° and 25°C

H. Derendorf, R. Hatton, Vipul Kumar, 2006 .

In vitro pharmacokinetics/pharmacodynamics of the combination of avibactam and aztreonam against MDR organisms.

Virna J. A. Schuck, H. Derendorf, M. Mulder, 2016, The Journal of antimicrobial chemotherapy.

Mycobacterium tuberculosis Strains H37ra and H37rv have equivalent minimum inhibitory concentrations to most antituberculosis drugs

H. Derendorf, C. Peloquin, M. T. Heinrichs, 2018, International journal of mycobacteriology.

A Redox-Based System that Enhances Delivery of Estradiol to the Brain: Pharmacokinetic Evaluation in the Dog

N. Bodor, M. Brewster, H. Derendorf, 1990, Pharmaceutical Research.

High-Performance Liquid Chromatographic Assay of a Central Nervous System (CNS)-Directed Estradiol Chemical Delivery System and Its Application After Intravenous Administration to Rats

N. Bodor, M. Brewster, H. Derendorf, 1988, Pharmaceutical Research.

Towards precision dosing of vancomycin: a systematic evaluation of pharmacometric models for Bayesian forecasting.

R. Day, D. Marriott, S. Wicha, 2019, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Penetration of ertapenem into skeletal muscle and subcutaneous adipose tissue in healthy volunteers measured by in vivo microdialysis.

M. Grant, M. Brunner, H. Derendorf, 2006, The Journal of antimicrobial chemotherapy.

How Important Are Gender Differences in Pharmacokinetics?

Hartmut Derendorf, Bernd Meibohm, B. Meibohm, 2002, Clinical pharmacokinetics.

A need to revisit clinical breakpoints of tigecycline: effect of atypical non-linear plasma protein binding.

H. Derendorf, R. S. Singh, Stefanie K. Drescher, 2017, International journal of antimicrobial agents.

Race‐Specific Pharmacodynamic Model of Propofol‐Induced Loss of Consciousness

Benjamin C. Lok, S. Lampotang, D. Lizdas, 2016, Journal of clinical pharmacology.

Nonlinear Protein Binding: Not What You Think.

H. Derendorf, R. S. Singh, A. Deitchman, 2018, Journal of pharmaceutical sciences.

Basic concepts of pharmacokinetic/pharmacodynamic (PK/PD) modelling.

H Derendorf, B. Meibohm, H. Derendorf, 1997, International journal of clinical pharmacology and therapeutics.

Modeling of Pharmacokinetic/Pharmacodynamic (PK/PD) Relationships: Concepts and Perspectives

Hartmut Derendorf, Bernd Meibohm, B. Meibohm, 1999, Pharmaceutical Research.

Role of Divalent Metal Ions in Atypical Nonlinear Plasma Protein Binding Behavior of Tigecycline.

H. Derendorf, R. S. Singh, A. Deitchman, 2016, Journal of pharmaceutical sciences.

A Pharmacokinetic/Pharmacodynamic Approach to Predict Total Prednisolone Concentrations in Human Plasma

H. Derendorf, J. Winkler, J. Xu, 2007, Journal of Pharmacokinetics and Pharmacodynamics.

How the lung handles drugs: pharmacokinetics and pharmacodynamics of inhaled corticosteroids.

Hartmut Derendorf, H. Derendorf, G. Hochhaus, 2004, Proceedings of the American Thoracic Society.

Knowledge Sharing, and Training Are Critical for Future Success Pharmacometrics as a Discipline Is Entering the ''Industrialization'' Phase: Standards, Automation,

Hartmut Derendorf, Klaus Romero, Bernd Meibohm, 2010 .

Pharmacokinetic/Pharmacodynamic Modeling in Drug Research and Development

Hartmut Derendorf, Gerald Rhodes, Raymond Miller, 2000, Journal of clinical pharmacology.

A model-based analysis of pharmacokinetic-pharmacodynamic (PK/PD) indices of avibactam against Pseudomonas aeruginosa.

H. Derendorf, H. Xia, S. Sy, 2019, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Introduction to Pharmacometrics and Quantitative Pharmacology with an Emphasis on Physiologically Based Pharmacokinetics

Xiaofeng Wang, Hartmut Derendorf, Sherwin K. B. Sy, 2014 .

Pharmacokinetic/pharmacodynamic studies in drug product development.

Hartmut Derendorf, Bernd Meibohm, B. Meibohm, 2002, Journal of pharmaceutical sciences.

Influence of CYP3A5 6986A > G and ABCB1 3435C > T Polymorphisms on Adverse Events Associated With Tacrolimus in Jordanian Pediatric Renal Transplant Patients

H. Derendorf, S. Shilbayeh, D. Conrado, 2013, Clinical pharmacology in drug development.

Influence of CYP 3 A 5 6986 A > G and ABCB 1 3435 C > T Polymorphisms on Adverse Events Associated With Tacrolimus in Jordanian Pediatric Renal Transplant Patients

H. Derendorf, S. Shilbayeh, D. Conrado, 2013 .

Carvacrol loaded nanostructured lipid carriers as a promising parenteral formulation for leishmaniasis treatment.

Jeferson S. Santos, H. Derendorf, P. Kima, 2020, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Drugs in space: Pharmacokinetics and pharmacodynamics in astronauts.

Hartmut Derendorf, H. Derendorf, C. Seubert, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in db/db Mice

M. Boulton, L. Adorini, R. Mirmira, 2018, Diabetes.

HPLC method validation for the quantification of lomustine to study pharmacokinetics of thermosensitive liposome-encapsulated lomustine containing iohexol for CT imaging in C6 glioma rats

H. Derendorf, Bingjie Zhang, Changxiao Liu, 2011, European Journal of Drug Metabolism and Pharmacokinetics.

Molecular and clinical pharmacology of intranasal corticosteroids: clinical and therapeutic implications

E. Meltzer, H. Derendorf, Hartmut Derendorf, 2008, Allergy.

Pharmacokinetics and Rectal Bioavailability of Hydrocortisone Acetate after Single and Multiple Administration in Healthy Subjects and Patients

H. Möllmann, J. Barth, H. Derendorf, 2001, Journal of clinical pharmacology.

How the Lung Handles Drugs

H. Derendorf, G. Hochhaus, J. Winkler, 2012 .

Pharmacokinetic/Pharmacodynamic Evaluation of Systemic Effects of Flunisolide after Inhalation

B. Meibohm, H. Möllmann, H. Derendorf, 1997, Journal of clinical pharmacology.

Pharmacokinetics and rectal bioavailability of hydrocortisone acetate.

S. Tunn, H. Möllmann, J. Barth, 1991, Journal of pharmaceutical sciences.

A Pharmacokinetic/Pharmacodynamic Approach to Predict the Cumulative Cortisol Suppression of Inhaled Corticosteroids

B. Meibohm, H. Möllmann, J. Barth, 1999, Journal of Pharmacokinetics and Biopharmaceutics.

Pharmacokinetic and pharmacodynamic modeling of cetrorelix, an LH‐RH antagonist, after subcutaneous administration in healthy premenopausal women

H. Derendorf, R. Hermann, K. Erb, 2000, Clinical pharmacology and therapeutics.

Clinical and pharmacological aspects of accidental triamcinolone acetonide overdosage: a case study.

H. Derendorf, S. Krishnaswami, D. Schweitzer, 2000, The Netherlands journal of medicine.

Repeated pre-exposure to tobacco smoke potentiates subsequent locomotor responses to nicotine and tobacco smoke but not amphetamine in adult rats

H. Derendorf, A. Bruijnzeel, Rajendra P. Singh, 2011, Pharmacology Biochemistry and Behavior.

Pharmacokinetics of Detirelix Following Intratracheal Instillation and Aerosol Inhalation in the Unanesthetized Awake Sheep

H. Schreier, H. Derendorf, Z. Teitelbaum, 1994, Pharmaceutical Research.

Feasibility of a Breath Test for Monitoring Adherence to Vaginal Administration of Antiretroviral Microbicide Gels

A. van der Straten, D. Dennis, H. Derendorf, 2013, Journal of clinical pharmacology.

Quantitation of the impact of CYP3A5 A6986G polymorphism on quetiapine pharmacokinetics by simulation of target attainment

H. Derendorf, S. Shilbayeh, S. Sy, 2015, Clinical pharmacology in drug development.

Oral Adherence Monitoring Using a Breath Test to Supplement Highly Active Antiretroviral Therapy

J. Simoni, D. Dennis, S. McGorray, 2012, AIDS and Behavior.

Clinical Pharmacology of Addicting Drugs

H. Derendorf, Jiang-qin Liu, 2010 .

The Candida albicans phosphatase Inp51p interacts with the EH domain protein Irs4p, regulates phosphatidylinositol-4,5-bisphosphate levels and influences hyphal formation, the cell integrity pathway and virulence.

K. Iczkowski, H. Derendorf, M. Nguyen, 2008, Microbiology.

Pharmacokinetic and Pharmacodynamic Considerations in Elderly Population

H. Derendorf, R. S. Singh, J. Mukker, 2016 .

In Vitro to In Vivo Extrapolation of Pharmacokinetic Drug Interactions between Clarithromycin and Ranitidine with Trospium Chloride to Evaluate Probe Drug Characteristics for P-glycoprotein and Organic Cation Transporter Functions in Human Inauguraldissertation

H. Derendorf, 2019 .

Skin and soft tissue concentrations of tedizolid (formerly torezolid), a novel oxazolidinone, following a single oral dose in healthy volunteers.

M. Grant, H. Derendorf, C. Seubert, 2012, International journal of antimicrobial agents.

Ceftobiprole medocaril (BAL-5788) for the treatment of complicated skin infections

H. Derendorf, D. de Jong, A. Barbour, 2016, Expert review of anti-infective therapy.

Integration of pharmacokinetic/pharmacodynamic modeling and simulation in the development of new anti-infective agents – minimum inhibitory concentration versus time-kill curves

E. Schuck, H. Derendorf, S. Schmidt, 2007, Expert opinion on drug discovery.

Resistance and the management of complicated skin and skin structure infections: the role of ceftobiprole

H. Derendorf, A. Barbour, 2010, Therapeutics and clinical risk management.

Applications of Pharmacokinetic/Pharmacodynamic Models for the Development of Antimicrobial Agents

Hartmut Derendorf, April Barbour, H. Derendorf, 2012 .

Soft-Tissue Penetration of Ceftobiprole in Healthy Volunteers Determined by In Vivo Microdialysis

M. Grant, H. Derendorf, C. Seubert, 2009, Antimicrobial Agents and Chemotherapy.

Microdialysis. A novel tool for clinical studies of anti-infective agents.

H. Derendorf, C. Joukhadar, M. Müller, 2001, European journal of clinical pharmacology.

A selective HPLC/RIA for dexamethasone and its prodrug dexamethasone-21-sulphobenzoate sodium in biological fluids.

H. Möllmann, H. Derendorf, G. Hochhaus, 1992, Biomedical chromatography : BMC.

Preadolescent tobacco smoke exposure leads to acute nicotine dependence but does not affect the rewarding effects of nicotine or nicotine withdrawal in adulthood in rats

H. Derendorf, A. Bruijnzeel, Elysia Small, 2010, Pharmacology Biochemistry and Behavior.

Evaluation of in vitro synergy between vertilmicin and ceftazidime against Pseudomonas aeruginosa using a semi-mechanistic pharmacokinetic/pharmacodynamic model.

H. Derendorf, H. Xia, Changxiao Liu, 2015, International journal of antimicrobial agents.

Core Entrustable Professional Activities in Clinical Pharmacology: Pearls for Clinical Practice

A. Rostami-Hodjegan, H. Derendorf, R. Hermann, 2018, Journal of clinical pharmacology.

Estimation of lithium clearance from routine clinical data in Egyptian bipolar patients. A population pharmacokinetic approach.

H. Derendorf, V. Kumar, E. Eldesoky, 2008, International journal of clinical pharmacology and therapeutics.

Pharmacokinetic-pharmacodynamic modelling of antibacterial activity of cefpodoxime and cefixime in in vitro kinetic models.

H. Derendorf, K. Rand, Ping Liu, 2005, International journal of antimicrobial agents.

Assessment of Glucocorticoid Lung Targeting by ex-Vivo Receptor Binding Studies in Rats

H. Schreier, H. Derendorf, R. Gonzalez-Rothi, 2004, Pharmaceutical Research.

Dose Optimization Based on Pharmacokinetic-Pharmacodynamic Modeling

Hartmut Derendorf, H. Derendorf, G. Hochhaus, 2019, Handbook of Pharmacokinetic/Pharmacodynamic Correlation.

Novel Formulations of Cetrorelix Acetate in Healthy Men: Pharmacodynamic Effects and Noncompartmental Pharmacokinetics

K. Junge, H. Derendorf, R. Hermann, 2002, Journal of clinical pharmacology.

Pharmacodynamics of Methylprednisolone Phosphate After Single Intravenous Administration to Healthy Volunteers

S. Tunn, H. Möllmann, J. Barth, 1991, Pharmaceutical Research.

[Pharmacokinetics and pharmacodynamics of prednisolone following extremely high dosage as prednisolone hemisuccinate].

H. Möllmann, J. Barth, H. Derendorf, 1987, Arzneimittel-Forschung.

Theory and Application of Microdialysis in Pharmacokinetic Studies.

H. Derendorf, H. Xia, Changxiao Liu, 2015, Current drug metabolism.

In vivo-in vitro correlations of salicylate saliva levels and continuous flow cell dissolution rates

H. Derendorf, P. Rohdewald, G. Drehsen, 1983 .

Antipyrine - New Light on an Old Drug

H. Derendorf, P. Rohdewald, G. Drehsen, 1984, Pharmaceutical Research.

Clinical microdialysis : Current applications and potential use in drug development

Hartmut Derendorf, Martin Brunner, M. Brunner, 2006 .

Comparison of talinolol and atenolol effects on blood pressure in relation to lipid and glucose metabolic parameters. Results from the TALIP study.

H. Derendorf, H. Sourgens, J. Schmidt, 2003, International journal of clinical pharmacology and therapeutics.

H. Derendorf, M. Ibarra, M. Vázquez, 2013, Journal of Pharmacokinetics and Pharmacodynamics.

Simultaneous Characterization of Intravenous and Oral Pharmacokinetics of Lychnopholide in Rats by Transit Compartment Model

N. Lopes, H. Derendorf, S. Sy, 2015, Planta Medica.

Electroencephalogram-based pharmacodynamic measures: a review

Hartmut Derendorf, Michael Bewernitz, H. Derendorf, 2012, International journal of clinical pharmacology and therapeutics.

Pulmonary Targeting of Liposomal Triamcinolone Acetonide Phosphate

H. Schreier, H. Derendorf, T. Dalla Costa, 1996, Pharmaceutical Research.

Pharmacokinetics of triamcinolone acetonide and its phosphate ester

H. Möllmann, H. Derendorf, P. Rohdewald, 2004, European Journal of Clinical Pharmacology.

Microdialysis for in vivo pharmacokinetic/pharmacodynamic characterization of anti-infective drugs.

M. Brunner, H. Derendorf, Markus Müller, 2005, Current opinion in pharmacology.

Pitfalls in Pharmacokinetic Multicompartment Analysis

Hartmut Derendorf, H. Derendorf, Earvin Liang, 1998, Journal of Pharmacokinetics and Biopharmaceutics.

Modeling in Pharmacometrics

H. Derendorf, W. Weber, Yichao Yu, 2019 .

Pharmacometrics as a Discipline Is Entering the “Industrialization” Phase: Standards, Automation, Knowledge Sharing, and Training Are Critical for Future Success

Marc R Gastonguay, Hartmut Derendorf, Klaus Romero, 2010, Journal of clinical pharmacology.

Systemic availability and pharmacokinetics of thymol in humans.

H. Derendorf, B. Brinkhaus, M. Veit, 2010, Journal of clinical pharmacology.

Dipyridamole Bioavailability in Subjects With Reduced Gastric Acidity

T. Macgregor, H. Derendorf, C. VanderMaelen, 2005, Journal of clinical pharmacology.

Codeine Disposition in Sickle Cell Patients Compared With Healthy Volunteers

H. Derendorf, S. Gross, A. Kedar, 1993, Journal of clinical pharmacology.

A Redox-Based Chemical Delivery System that Enhances Estradiol Distribution to the Brain: Disposition Studies in the Rat

N. Bodor, M. Brewster, H. Derendorf, 1991, Pharmaceutical Research.

A Markov Chain Model to Evaluate the Effect of CYP3A5 and ABCB1 Polymorphisms on Adverse Events Associated with Tacrolimus in Pediatric Renal Transplantation

H. Derendorf, S. Shilbayeh, D. Conrado, 2013, The AAPS Journal.

Human serum binding and its effect on the pharmacodynamics of the lantibiotic MU1140.

J. Hillman, H. Derendorf, Oliver G Ghobrial, 2010, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Pharmacokinetic and pharmacodynamic evaluation of the lantibiotic MU1140.

J. Hillman, H. Derendorf, OLIVER GHOBRIAL, 2010, Journal of pharmaceutical sciences.

Development and validation of a LC-MS quantification method for the lantibiotic MU1140 in rat plasma.

J. Hillman, H. Derendorf, Oliver G Ghobrial, 2009, Journal of pharmaceutical and biomedical analysis.

Pharmacometrics in dose finding or dose optimization of anti-retroviral and anti-tubercular drugs.

H. Derendorf, S. Sabarinath, C. Peloquin, 2011, Infectious disorders drug targets.

Electroencephalogram effects of armodafinil: Comparison with behavioral alertness

M. Ding, S. Eisenschenk, J. Cibula, 2013, Journal of clinical pharmacology.

Cortisol suppression as a surrogate marker for inhaled corticosteroid-induced growth retardation in children.

H. Derendorf, S. Sabarinath, Jian Xu, 2009, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Concentration-response studies and modelling of the pharmacodynamics of linezolid: Staphylococcus aureus versus Enterococcus faecium.

S. Wicha, C. Kloft, H. Derendorf, 2015, International journal of antimicrobial agents.

Lung Tissue Concentrations of Pyrazinamide among Patients with Drug-Resistant Pulmonary Tuberculosis

J. Guarner, T. Read, Adam Bernheim, 2017, Antimicrobial Agents and Chemotherapy.

Pharmacokinetics of Rimexolone After Intra‐Articular Administration

J. Dequeker, H. Möllmann, H. Derendorf, 1990, Journal of clinical pharmacology.

Pharmacokinetic Aspects of Intra-articular Administration of Glucocorticoids

H. Möllmann, J. Barth, H. Derendorf, 1989 .

Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs.

O. Cars, G. Drusano, H. Derendorf, 2002, International journal of antimicrobial agents.

Underdosing of ertapenem in critically ill patients with pneumonia confirmed by Monte Carlo simulations.

T. Welte, H. Derendorf, J. Kielstein, 2010, International journal of antimicrobial agents.

PK/PD: new insights for antibacterial and antiviral applications.

Stephan Schmidt, Hartmut Derendorf, April Barbour, 2008, Current opinion in pharmacology.

Clinical development of an advanced intranasal delivery system of azelastine hydrochloride and fluticasone propionate.

G. Canonica, E. Meltzer, H. Derendorf, 2014, Drugs of today.

Serum concentrations and clinical effects of atorvastatin in patients taking grapefruit juice daily.

D. Greenblatt, J. Harmatz, K. Browne, 2011, British journal of clinical pharmacology.

Impact of tazobactam pharmacokinetics on the antimicrobial effect of piperacillin-tazobactam combinations.

H. Derendorf, K. Rand, Q. Liu, 2004, International journal of antimicrobial agents.

Pharmacokinetic-Pharmacodynamic Modeling of the In Vitro Activities of Oxazolidinone Antimicrobial Agents against Methicillin-Resistant Staphylococcus aureus (cid:1)

H. Derendorf, S. Sabarinath, P. Manitpisitkul, 2009 .

Principles of Applied Pharmacokinetic–Pharmacodynamic Modeling

Hartmut Derendorf, Benjamin Wu, Sherwin K. B. Sy, 2014 .

Pharmacokinetic/Pharmacodynamic Modeling of Antibiotics

H. Derendorf, A. Nolting, 2019, Handbook of Pharmacokinetic/Pharmacodynamic Correlation.

Protein Binding of Rifapentine and Its 25-Desacetyl Metabolite in Patients with Pulmonary Tuberculosis

W. M. Mac Kenzie, H. Derendorf, T. Prihoda, 2014, Antimicrobial Agents and Chemotherapy.

Measurement of Voriconazole Activity against Candida albicans, C. glabrata, and C. parapsilosis Isolates Using Time-Kill Methods Validated by High-Performance Liquid Chromatography

H. Derendorf, C. Clancy, M. Nguyen, 2007, Antimicrobial Agents and Chemotherapy.

Predicting Pediatric Age-Matched Weight and Body Mass Index

H. Derendorf, E. Samara, S. Sy, 2014, AAPS Journal.

Pharmacokinetics and pharmacodynamics of prednisolone after intravenous and oral administration.

H. Möllmann, J. Barth, H. Derendorf, 1992, International journal of clinical pharmacology, therapy, and toxicology.

Pharmacokinetic-Pharmacodynamic Correlations of Corticosteroids

H. Möllmann, J. Barth, H. Derendorf, 2019, Handbook of Pharmacokinetic/Pharmacodynamic Correlation.

Pharmacokinetics of piperacillin, tazobactam and its metabolite in renal impairment.

H. Derendorf, T. Dalla Costa, 1996, International journal of clinical pharmacology and therapeutics.

Microdialysis

H. Derendorf, Markus Müller, C. Joukhadar, 2001 .

Pharmacokinetics and Pharmacodynamics of Dexamethasone Sodium‐m‐Sulfobenzoate (DS) after Intravenous and Intramuscular Administration: A Comparison with Dexamethasone Phosphate (DP)

H. Möllmann, J. Barth, H. Derendorf, 2001, Journal of clinical pharmacology.

Pharmacokinetics and dose linearity testing of methylprednisolone phosphate.

H. Möllmann, J. Barth, H. Derendorf, 1989, Biopharmaceutics & drug disposition.

Gastric-acid-mediated drug-drug interactions with direct-acting antiviral medications for hepatitis C virus infection: clinical relevance and mitigation strategies.

H. Derendorf, Guo-Fu Li, Yichao Yu, 2019, Drug discovery today.

Pharmacokinetic-pharmacodynamic relationships for analgesics.

G Geisslinger, H Derendorf, H. Derendorf, 1997, International journal of clinical pharmacology and therapeutics.

Biowaiver monographs for immediate release solid oral dosage forms: prednisolone.

D. Barends, H. Junginger, S. Stavchansky, 2007, Journal of pharmaceutical sciences.

COMMENTARY Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Prednisolone

D. Barends, H. Derendorf, M. Vogt, 2007 .

A comparison of linezolid lung tissue concentrations among patients with drug-resistant tuberculosis

Adam Bernheim, B. Little, H. Derendorf, 2018, European Respiratory Journal.

Studies on the pharmacokinetics and metabolism of prednicarbate after cutaneous and oral administration.

H. Möllmann, J. Barth, H. Derendorf, 1993, Skin Pharmacology.

Influence of the Duffy Antigen on Pharmacokinetics and Pharmacodynamics of Recombinant Monocyte Chemoattractant Protein (MCP-1, CCL-2) in Vivo

J. Leitner, H. Derendorf, B. Jilma, 2009, International journal of immunopathology and pharmacology.

Role of drug absorption in the pharmacokinetics of therapeutic interventions for stroke

H. Derendorf, D. Conrado, D. Gonzalez, 2010, Annals of the New York Academy of Sciences.

Tissue concentrations: do we ever learn?

O. Cars, W. Craig, P. Tulkens, 2007, The Journal of antimicrobial chemotherapy.

Biowaiver monographs for immediate release solid oral dosage forms: prednisone.

D. Barends, H. Junginger, S. Stavchansky, 2007, Journal of pharmaceutical sciences.

Human serum binding and its effect on the pharmacodynamics of the lantibiotic MU1140.

J. Hillman, H. Derendorf, Oliver G Ghobrial, 2010, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Pharmacodynamic activity of the lantibiotic MU1140.

H. Derendorf, J. Hillman, Oliver G Ghobrial, 2009, International journal of antimicrobial agents.

Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in db/db Mice

M. Boulton, L. Adorini, R. Mirmira, 2018, Diabetes.

Serum concentrations and clinical effects of atorvastatin in patients taking grapefruit juice daily.

D. Greenblatt, J. Harmatz, K. Browne, 2011, British journal of clinical pharmacology.

Assessment of the Impact of Dosing Time on the Pharmacokinetics/Pharmacodynamics of Prednisolone

H. Derendorf, S. Sabarinath, J. Winkler, 2008, The AAPS Journal.

Effect of reducing the paediatric stavudine dose by half: a physiologically-based pharmacokinetic model.

M. Cotton, H. Derendorf, S. Sy, 2015, International Journal of Antimicrobial Agents.

Pharmacokinetic Evaluation of Avicularin Using a Model-Based Development Approach

N. Lopes, H. Derendorf, S. Sy, 2015, Planta Medica.

Predicting Pediatric Age-Matched Weight and Body Mass Index

H. Derendorf, E. Samara, S. Sy, 2014, The AAPS Journal.

Improved delivery through biological membranes. XXXL: Solubilization and stabilization of an estradiol chemical delivery system by modified beta-cyclodextrins.

N. Bodor, M. Brewster, H. Derendorf, 1988, Journal of pharmaceutical sciences.

Bioavailability and pharmacokinetics of caffeoylquinic acids and flavonoids after oral administration of Artichoke leaf extracts in humans.

H. Derendorf, T. Windeck, M. Ploch, 2005, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Guangji Wang, H. Derendorf, W. Zhong, 2019, Clinical Pharmacokinetics.

Pharmacodynamic Evaluation of Codeine Using Tooth Pulp Evoked Potentials

H Derendorf, H. Derendorf, B. L. Grundy, 1996, Journal of clinical pharmacology.

Pharmacokinetics of Intravenous Immunoglobulin (Gammagard) in Bone Marrow Transplant Patients

J. Graham-Pole, H. Derendorf, K. Rand, 1991, Journal of clinical pharmacology.