D. Holden

发表

SpvC is a Salmonella effector with phosphothreonine lyase activity on host mitogen-activated protein kinases

P. Sansonetti, P. Mazurkiewicz, Jerry R. Thomas, 2008, Molecular microbiology.

Salmonella SPI-2 Type III Secretion System Effectors: Molecular Mechanisms And Physiological Consequences.

David W Holden, D. Holden, Elliott Jennings, 2017, Cell host & microbe.

Simultaneous identification of bacterial virulence genes by negative selection.

J. Shea, M. Hensel, D. Holden, 1995, Science.

Identification of a virulence locus encoding a second type III secretion system in Salmonella typhimurium.

J. Shea, M. Hensel, D. Holden, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Analysis of the boundaries of Salmonella pathogenicity island 2 and the corresponding chromosomal region of Escherichia coli K-12

F. Blattner, J. Shea, M. Hensel, 1997, Journal of bacteriology.

Functions of the Salmonella pathogenicity island 2 (SPI-2) type III secretion system effectors.

D. Holden, Rita Figueira, 2012, Microbiology.

A Locus Contained within a Variable Region of Pneumococcal Pathogenicity Island 1 Contributes to Virulence in Mice

B. Spratt, Jeremy S. Brown, D. Holden, 2004, Infection and Immunity.

Type II Toxin-Antitoxin Systems and Persister Cells

J. Errington, D. Holden, 2018, mBio.

Internalization of Salmonella by Macrophages Induces Formation of Nonreplicating Persisters

David W. Holden, Angela M. Cheverton, D. Holden, 2014, Science.

Dynamics of intracellular bacterial replication at the single cell level

Jessica A. Thompson, Mei Liu, D. Holden, 2010, Proceedings of the National Academy of Sciences.

Signature-tagged mutagenesis: barcoding mutants for genome-wide screens

Charles Boone, Piotr Mazurkiewicz, David W. Holden, 2006, Nature Reviews Genetics.

RrgA is a pilus-associated adhesin in Streptococcus pneumoniae

R. Rappuoli, S. Normark, J. Tschöp, 2007, Molecular microbiology.

Probing the active site of mitogillin, a fungal ribotoxin

J. Shea, D. Holden, J. Davies, 1998, Molecular microbiology.

Construction and pathogenicity of Aspergillus fumigatus mutants that do not produce the ribotoxin restrictocin

J. Davies, D. Holden, J. Smith, 1993, Molecular microbiology.

Virulence of Aspergillus fumigatus double mutants lacking restriction and an alkaline protease in a low-dose model of invasive pulmonary aspergillosis

C. Tang, D. Holden, S. Van Noorden, 1994, Infection and immunity.

Type III secretion systems: what is the translocator and what is translocated?

G. Cornelis, D. Holden, A. Blocker, 2000, Cellular microbiology.

The Multiple Interactions between Salmonella and Phagocytes

Jessica A. Thompson, D. Holden, 2009 .

Macrophage Nitric Oxide Synthase Associates with Cortical Actin but Is Not Recruited to Phagosomes

D. Holden, T. Evans, J. L. Webb, 2001, Infection and Immunity.

A functional genomic analysis of type 3 Streptococcus pneumoniae virulence

M. Lonetto, D. Holden, G. Lau, 2001, Molecular microbiology.

Src-dependent Tyrosine Phosphorylation of Non-muscle Myosin Heavy Chain-IIA Restricts Listeria monocytogenes Cellular Infection*

D. Holden, J. Leong, D. Cabanes, 2015, The Journal of Biological Chemistry.

Ubiquitination - a bacterial effector's ticket to ride.

Mair E. M. Thomas, D. Holden, 2009, Cell host & microbe.

The detection of Aspergillus spp. by the polymerase chain reaction and its evaluation in bronchoalveolar lavage fluid.

C. Tang, J. Cohen, D. Holden, 1993, The American review of respiratory disease.

Influence of the Salmonella typhimuriumPathogenicity Island 2 Type III Secretion System on Bacterial Growth in the Mouse

J. Shea, C. Beuzón, D. Holden, 1999, Infection and Immunity.

SteC and the intracellular Salmonella‐induced F‐actin meshwork

O. Cerny, D. Holden, A. Heggie, 2021, Cellular microbiology.

Salmonella pathogenicity island-2 and anticancer activity in mice

Samuel I. Miller, J. Platt, A. Chakraborty, 2002, Cancer Gene Therapy.

Evaluation of Salmonella typhimuriumMutants in a Model of Experimental Gastroenteritis

G. Dougan, D. Maskell, J. Ketley, 1999, Infection and Immunity.

Salmonella typhimurium SifA Effector Protein Requires Its Membrane-anchoring C-terminal Hexapeptide for Its Biological Function*

J. Gorvel, S. Méresse, E. Boucrot, 2003, The Journal of Biological Chemistry.

Global mapping of Salmonella enterica-host protein-protein interactions during infection

M. Savitski, K. Rottner, A. Typas, 2020, bioRxiv.

Identification of Salmonella Pathogenicity Island-2 Type III Secretion System Effectors Involved in Intramacrophage Replication of S. enterica Serovar Typhimurium: Implications for Rational Vaccine Design

D. Holden, Rita Figueira, S. Helaine, 2013, mBio.

Lack of Effect of the Salmonella Deubiquitinase SseL on the NF-κB Pathway

D. Holden, Nathalie Rolhion, F. Mesquita, 2013, PloS one.

Molecular genetic approaches for the study of virulence in both pathogenic bacteria and fungi.

M. Hensel, D. Holden, Michael Hensel, 1996, Microbiology.

Evolution of transcription-regulating proteins: caveat lector!

H. Arst, D. Holden, M. Caddick, 1997, Gene.

The Tumour Suppressor TMEM127 Is a Nedd4-Family E3 Ligase Adaptor Required by Salmonella SteD to Ubiquitinate and Degrade MHC Class II Molecules

J. Pruneda, D. Komander, O. Cerny, 2020, Cell host & microbe.

Staphylococcus aureus svrA: a gene required for virulence and expression of the agr locus.

D. Holden, S. Garvis, Javier Ruiz-Albert, 2002, Microbiology.

The roles of SsrA-SsrB and OmpR-EnvZ in the regulation of genes encoding the Salmonella typhimurium SPI-2 type III secretion system.

C. Beuzón, D. Holden, J. Garmendia, 2003, Microbiology.

The Salmonella Deubiquitinase SseL Inhibits Selective Autophagy of Cytosolic Aggregates

Mair E. M. Thomas, M. Sachse, D. Holden, 2012, PLoS pathogens.

of Healthy Volunteers ) Mutations by ssaV Secretion System ( Pathogenicity Island 2 Type III Salmonella and aroC Derivatives Harboring Defined Salmonella enterica Characterization of

Marjan, Immunization., G. Dougan, 2002 .

Bacterial Interference of Ubiquitination and Deubiquitination

D. Holden, A. Rytkönen, 2007, Cell Host & Microbe.

Erratum for O’Neill et al., Cytosolic Replication of Group A Streptococcus in Human Macrophages

D. Holden, Teresa L. M. Thurston, Alan M. O’Neill, 2016, mBio.

Cytosolic Replication of Group A Streptococcus in Human Macrophages

D. Holden, Teresa L. M. Thurston, Alan M. O’Neill, 2016, mBio.

The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases

Balaji Santhanam, H. Ovaa, J. Pruneda, 2016, Molecular cell.

The SPI-2 type III secretion system restricts motility of Salmonella-containing vacuoles

S. Shorte, S. Münter, L. J. Mota, 2007, Cellular microbiology.

Dynamin is required for F‐actin assembly and pedestal formation by enteropathogenic Escherichia coli (EPEC)

M. McNiven, M. Way, P. Mazurkiewicz, 2007, Cellular microbiology.

Immunization with Components of Two Iron Uptake ABC Transporters Protects Mice against Systemic Streptococcus pneumoniae Infection

Jeremy S. Brown, A. Ogunniyi, D. Holden, 2001, Infection and Immunity.

Dynamics of growth and dissemination of Salmonella in vivo

D. Holden, Kathryn G. Watson, 2010, Cellular microbiology.

Use of mixed infections with Salmonella strains to study virulence genes and their interactions in vivo.

C. Beuzón, D. Holden, 2001, Microbes and infection.

FlAsHlights on bacterial virulence proteins

L. J. Mota, D. Holden, 2005, Nature Methods.

The Salmonella Effector SteA Contributes to the Control of Membrane Dynamics of Salmonella-Containing Vacuoles

L. J. Mota, D. Holden, Lia Domingues, 2014, Infection and Immunity.

CD97 stabilises the immunological synapse between dendritic cells and T cells and is targeted for degradation by the Salmonella effector SteD

P. Lehner, O. Cerny, D. Holden, 2021, PLoS pathogens.

Septicemia Streptococcus pneumoniae Facilitates Deposition by Pneumolysin and PspA Additive Inhibition of Complement

Jeremy S. Brown, D. Holden, M. Botto, 2005 .

SCAMP3 is a component of the Salmonella-induced tubular network and reveals an interaction between bacterial effectors and post-Golgi trafficking

L. J. Mota, Mei Liu, D. Holden, 2009, Cellular microbiology.

Linking approaches in the study of fungal pathogenesis: a commentary.

J. Hamer, D. Holden, 1997, Fungal genetics and biology : FG & B.

Cloning the REC1 gene of Ustilago maydis

N. Kanuga, A. Spanos, D. Holden, 1991, Current Genetics.

The Translocated Salmonella Effector Proteins SseF and SseG Interact and Are Required To Establish an Intracellular Replication Niche

J. Gorvel, S. Méresse, T. Henry, 2006, Infection and Immunity.

Salmonella enterica serovar Typhimurium interaction with dendritic cells: impact of the sifA gene

S. Clare, G. Dougan, N. Lemoine, 2004, Cellular microbiology.

Role for Salmonella enterica Enterobacterial Common Antigen in Bile Resistance and Virulence

J. Casadesús, F. Ramos-Morales, C. Beuzón, 2003, Journal of bacteriology.

Involvement of the intermediate filament protein cytokeratin‐18 in actin pedestal formation during EPEC infection

I. Connerton, N. Cummings, D. Holden, 2004, EMBO reports.

Identification and analysis of bacterial virulence genes in vivo.

D. Holden, K. E. Unsworth, 2000, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Mutation in a heat‐regulated hsp70 gene of Ustilago maydis.

J. Kronstad, D. Holden, S. Leong, 1989, The EMBO journal.

Salmonella SPI-2 type III secretion system-dependent inhibition of antigen presentation and T cell function.

O. Cerny, D. Holden, 2019, Immunology letters.

Detection of gene-disruption events in aspergillus transformants by polymerase chain reaction direct from conidiospores

D. Holden, A. Aufauvre-Brown, C. Tang, 1993, Current Genetics.

Sequestering of Rac by the Yersinia Effector YopO Blocks Fcγ Receptor-mediated Phagocytosis*

K. Rittinger, E. Caron, G. Cornelis, 2009, The Journal of Biological Chemistry.

A pneumococcal pilus influences virulence and host inflammatory responses.

R. Rappuoli, V. Masignani, S. Normark, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Recruited to Phagosomes Associates with Cortical Actin but Is Not Macrophage Nitric Oxide Synthase

D. Holden, T. Evans, J. L. Webb, 2001 .

Edwardsiella tarda-Induced Cytotoxicity Depends on Its Type III Secretion System and Flagellin

D. Holden, P. Nie, H. Xie, 2014, Infection and Immunity.

Salmonella Inhibits Retrograde Trafficking of Mannose-6-Phosphate Receptors and Lysosome Function

L. J. Mota, D. Holden, L. Pinaud, 2012, Science.

SlyA Regulates Function of Salmonella Pathogenicity Island 2 (SPI-2) and Expression of SPI-2-Associated Genes

Mei Liu, D. Holden, S. Linehan, 2005, Infection and Immunity.

Intracellular replication of Salmonella typhimurium strains in specific subsets of splenic macrophages in vivo

Jonathan D. Cohen, M. Noursadeghi, D. Holden, 2001, Cellular microbiology.

Isolation of metabolic genes and demonstration of gene disruption in the phytopathogenic fungus Ustilago maydis.

S. Covert, J. Kronstad, D. Holden, 1989, Gene.

Proteins in intercellular washing fluid from noninoculated and rust-affected leaves of wheat and barley.

D. Holden, R. Rohringer, 1985, Plant physiology.

The Salmonella SPI-2 effector SseJ exhibits eukaryotic activator-dependent phospholipase A and glycerophospholipid : cholesterol acyltransferase activity

A. Magee, D. Holden, C. Boyle, 2008, Microbiology.

In vivo genetic analysis of bacterial virulence.

S. L. Chiang, J. Mekalanos, D. Holden, 1999, Annual review of microbiology.

Preferential invasion of mitotic cells by Salmonella reveals that cell surface cholesterol is maximal during metaphase

M. Fessler, M. Meinecke, D. Holden, 2013, Journal of Cell Science.

The role of the Aspergillus fumigatus areA gene in invasive pulmonary aspergillosis.

M. Hensel, H. Arst, D. Holden, 1998, Molecular & general genetics : MGG.

The Salmonella Kinase SteC Targets the MAP Kinase MEK to Regulate the Host Actin Cytoskeleton

P. Freemont, A. Catling, D. Lamont, 2012, Cell host & microbe.

SsaV Interacts with SsaL to Control the Translocon-to-Effector Switch in the Salmonella SPI-2 Type Three Secretion System

L. J. Mota, Mei Liu, D. Holden, 2018, mBio.

The role of the Aspergillus fumigatusareA gene in invasive pulmonary aspergillosis

M. Hensel, D. Holden, A. Aufauvre-Brown, 1998, Molecular and General Genetics MGG.

The alkaline protease of Aspergillus fumigatus is not a virulence determinant in two murine models of invasive pulmonary aspergillosis

C. Tang, J. Cohen, Jonathan Cohen, 1993, Infection and immunity.

Gene transfer system for the phytopathogenic fungus Ustilago maydis.

D. Holden, S. Leong, J. Wang, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Clinical isolates Aspergillus clavatusc 2151 Clinical isolate Aspergillus terreusc 2026 Unknown Rhizopus oryzaed 129 Clinical isolate Fusarium oxysporumd 126 Clinical isolate Penicillium aurantiogriseuma 140 Clinical isolate Penicillium chrysogenuma 210 Clinical isolate Candida albicansa 97 Clinical

Jonathan Cohen, D. Holden, B. Bainbridge, 2022 .

phgABC, a Three-Gene Operon Required for Growth of Streptococcus pneumoniae in Hyperosmotic Medium and In Vivo

Jeremy S. Brown, D. Holden, S. Basavanna, 2004, Infection and Immunity.

A Streptococcus pneumoniae pathogenicity island encoding an ABC transporter involved in iron uptake and virulence

Jeremy S. Brown, D. Holden, S. M. Gilliland, 2001, Molecular microbiology.

Molecular Genetic Approaches to the Study of Fungal Pathogenesis

D. Holden, A. Leong, 1989 .

Variation in Pathogenicity Associated with the Genetic Diversity of Fusarium graminearum

J. Carter, P. Nicholson, D. Holden, 2002, European Journal of Plant Pathology.

Signs and portents: molecular signals and infectious diseases.

D. Holden, V. A. Snewin, 1999, Trends in microbiology.

Insertional mutagenesis of Aspergillus fumigatus

D. Holden, J. S. Brown, J. Brown, 1998, Molecular and General Genetics MGG.

Regulation of fungal extracellular proteases and their role in mammalian pathogenesis

M. Hensel, H. Arst, D. Holden, 1995 .

Virulence studies of Aspergillus nidulans mutants requiring lysine or p-aminobenzoic acid in invasive pulmonary aspergillosis

C. Tang, H. Arst, D. Holden, 1994, Infection and immunity.

Detection of Aspergillus fumigatus by Polymerase Chain Reaction

David Holden, D. Holden, B. Bainbridge, 1994, Journal of clinical microbiology.

An Aspergillus fumigatus alkaline protease mutant constructed by gene disruption is deficient in extracellular elastase activity

C. Tang, D. Holden, J. Cohen, 1992, Molecular microbiology.

The Salmonella transmembrane effector SteD hijacks AP1-mediated vesicular trafficking for delivery to antigen-loading MHCII compartments

O. Cerny, Mei Liu, D. Holden, 2022, bioRxiv.

Cell wall biogenesis in a double chitin synthase mutant (chsG-/chsE-) of Aspergillus fumigatus.

J. Latgé, P. Mol, D. Holden, 2003, Fungal genetics and biology : FG & B.

Aspergillus fumigatus chsE: a gene related to CHS3 of Saccharomyces cerevisiae and important for hyphal growth and conidiophore development but not pathogenicity.

N. Gow, D. Holden, E. Mellado, 1997, Fungal genetics and biology : FG & B.

A multigene family related to chitin synthase genes of yeast in the opportunistic pathogen Aspergillus fumigatus

P. Robbins, C. Specht, D. Holden, 1995, Molecular and General Genetics MGG.

Signature‐tagged and directed mutagenesis identify PABA synthetase as essential for Aspergillus fumigatus pathogenicity

H. Arst, Jeremy S. Brown, D. Holden, 2000, Molecular microbiology.

Cloning and characterization of chsD, a chitin synthase-like gene of Aspergillus fumigatus.

P. Robbins, C. Specht, D. Holden, 1996, FEMS microbiology letters.

The Aspergillus fumigatus chsC and chsG genes encode Class III chitin synthases with different functions

N. Gow, D. Holden, E. Mellado, 1996, Molecular microbiology.

Use of randomly amplified polymorphic DNA markers to distinguish isolates of Aspergillus fumigatus

D. Holden, J. Cohen, A. Aufauvre‐Brown, 1992, Journal of clinical microbiology.

Insertional mutagenesis of pathogenic fungi.

D. Holden, J. Brown, Jeremy S. Brown, 1998, Current opinion in microbiology.

Molecular epidemiological study of invasive pulmonary aspergillosis in a renal transplantation unit

C. Tang, J. Cohen, D. Holden, 1994, European Journal of Clinical Microbiology and Infectious Diseases.

Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death

F. Shao, D. Holden, M. Birrell, 2016, Nature Communications.

Protein blotting: detection of proteins with colloidal gold, and of glycoproteins and lectins with biotin-conjugated and enzyme probes.

D. Holden, R. Rohringer, 1985, Analytical biochemistry.

Salmonella Manipulation of Host Signaling Pathways Provokes Cellular Transformation Associated with Gallbladder Carcinoma.

A. Broeks, J. Neefjes, R. Spaapen, 2015, Cell host & microbe.

Identification of Staphylococcus aureus virulence genes in a murine model of bacteraemia using signature‐tagged mutagenesis

D. Holden, David W. Holden, C. W. Ford, 1997, Molecular microbiology.

Salmonella pathogenicity island 2-dependent evasion of the phagocyte NADPH oxidase.

F. Fang, M. Dinauer, P. Mastroeni, 2000, Science.

Interactions between Salmonella and the Autophagy System

D. Holden, Teresa L. M. Thurston, 2014 .

Genes encoding putative effector proteins of the type III secretion system of Salmonella pathogenicity island 2 are required for bacterial virulence and proliferation in macrophages

J. Shea, M. Hensel, D. Holden, 1998, Molecular microbiology.

Characterization of Pit, a Streptococcus pneumoniae Iron Uptake ABC Transporter

Jeremy S. Brown, D. Holden, S. M. Gilliland, 2002, Infection and Immunity.

DNA-mediated transformation of Ustilago hordei and Ustilago nigra☆

D. Holden, S. Leong, J. Wang, 1988 .

Molecular Analysis of Pathogenesis in Ustilago maydis

S. Covert, J. Kronstad, D. Samac, 1991 .

Transmembrane substrates of type three secretion system injectisomes

D. Holden, Camilla Godlee, 2023, Microbiology.

Salmonella Effectors SseF and SseG Interact with Mammalian Protein ACBD3 (GCP60) To Anchor Salmonella-Containing Vacuoles at the Golgi Network

Mei Liu, D. Holden, Xiu-jun Yu, 2016, mBio.

Clustered Intracellular Salmonella enterica Serovar Typhimurium Blocks Host Cell Cytokinesis

D. Holden, C. Durkin, S. Helaine, 2016, Infection and Immunity.

Membrane dynamics and spatial distribution of Salmonella-containing vacuoles.

L. J. Mota, D. Holden, Amy E Ramsden, 2007, Trends in microbiology.

SseG, a virulence protein that targets Salmonella to the Golgi network

D. Holden, S. Salcedo, 2003, The EMBO journal.

Salmonella maintains the integrity of its intracellular vacuole through the action of SifA

S. Méresse, C. Beuzón, D. Holden, 2000, The EMBO journal.

The Salmonella effector SteA binds phosphatidylinositol 4‐phosphate for subcellular targeting within host cells

V. J. Cid, M. Molina, L. J. Mota, 2016, Cellular microbiology.

pH Sensing by Intracellular Salmonella Induces Effector Translocation

Mei Liu, D. Holden, K. McGourty, 2010, Science.

pH‐dependent secretion of SseB, a product of the SPI‐2 type III secretion system of Salmonella typhimurium

M. Hensel, C. Beuzón, D. Holden, 1999, Molecular microbiology.

SrcA is a chaperone for the Salmonella SPI-2 type three secretion system effector SteD.

O. Cerny, D. Holden, C. Durkin, 2019, Microbiology.

The Salmonella Effector SteD Mediates MARCH8-Dependent Ubiquitination of MHC II Molecules and Inhibits T Cell Activation

S. Kaufmann, O. Cerny, N. Lapaque, 2016, Cell host & microbe.

SKIP, the Host Target of the Salmonella Virulence Factor SifA, Promotes Kinesin‐1‐Dependent Vacuolar Membrane Exchanges

S. Drevensek, J. Gorvel, S. Méresse, 2010, Traffic.

Complementary activities of SseJ and SifA regulate dynamics of the Salmonella typhimurium vacuolar membrane

Javier Ruiz-Albert, Xiu-Jun Yu, Carmen R Beuzón, 2002, Molecular microbiology.

Nurse culture for efficient recovery of cryopreserved Pinus radiata D. Don embryogenic cell lines

D. Holden, C. Hargreaves, L. Grace, 2002, Plant Cell Reports.

The Ustilago maydis nar 1 gene encoding nitrate reductase activity: sequence and transcriptional regulation

N. Kanuga, A. Spanos, D. Holden, 1993 .

PLEKHM1 regulates Salmonella-containing vacuole biogenesis and infection.

B. Maček, D. Bumann, A. Frangakis, 2015, Cell host & microbe.

Heterogeneity of intracellular replication of bacterial pathogens.

D. Holden, S. Helaine, 2013, Current opinion in microbiology.

Trafficking of the Salmonella Vacuole in Macrophages

D. Holden, David W. Holden, 2002, Traffic.

Growth and killing of a Salmonella enterica serovar Typhimurium sifA mutant strain in the cytosol of different host cell lines.

C. Beuzón, D. Holden, S. Salcedo, 2002, Microbiology.

SpiC is required for secretion of Salmonella Pathogenicity Island 2 type III secretion system proteins

Mei Liu, D. Holden, S. Garvis, 2002, Cellular microbiology.

Functional analysis of ssaJ and the ssaK/U operon, 13 genes encoding components of the type III secretion apparatus of Salmonella Pathogenicity Island 2

S. Falkow, J. Shea, M. Hensel, 1997, Molecular microbiology.

The classical pathway is the dominant complement pathway required for innate immunity to Streptococcus pneumoniae infection in mice

M. Walport, Jeremy S. Brown, D. Holden, 2002, Proceedings of the National Academy of Sciences of the United States of America.

SteC is a Salmonella kinase required for SPI-2-dependent F-actin remodelling

David W Holden, Paul Freemont, P. Freemont, 2007, Cellular microbiology.

Analysis of the mechanisms of Salmonella‐induced actin assembly during invasion of host cells and intracellular replication

M. McNiven, M. Way, D. Holden, 2004, Cellular microbiology.

SseL, a Salmonella deubiquitinase required for macrophage killing and virulence

P. Freemont, A. Thompson, J. Hinton, 2007, Proceedings of the National Academy of Sciences.

Characterization of the Streptococcus pneumoniae NADH oxidase that is required for infection.

M. Lonetto, M. Rosenberg, D. Holden, 2001, Microbiology.

Editorial policy on genome‐scale analyses

A. Cowman, B. Bassler, D. Holden, 2004 .

Iron acquisition by Gram-positive bacterial pathogens.

Jeremy S. Brown, D. Holden, 2002, Microbes and infection.

The Ustilago maydis pyr3 gene: sequence and transcriptional analysis.

N. Kanuga, A. Spanos, D. Holden, 1992, Gene.

SseA is a chaperone for the SseB and SseD translocon components of the Salmonella pathogenicity-island-2-encoded type III secretion system.

C. Beuzón, D. Holden, R. Mundy, 2003, Microbiology.

A glutamate‐alanine‐leucine (EAL) domain protein of Salmonella controls bacterial survival in mice, antioxidant defence and killing of macrophages: role of cyclic diGMP

Roger A. Jones, M. MacCoss, B. Gaffney, 2005, Molecular microbiology.

Global mapping of Salmonella enterica-host protein-protein interactions during infection.

M. Savitski, K. Rottner, M. Geyer, 2021, Cell host & microbe.

Functions and effectors of the Salmonella pathogenicity island 2 type III secretion system

D. Holden, S. Waterman, David W. Holden, 2003, Cellular microbiology.

In Vivo Genetic Analysis Indicates That PhoP-PhoQ and the Salmonella Pathogenicity Island 2 Type III Secretion System Contribute Independently to Salmonella enterica Serovar Typhimurium Virulence

C. Beuzón, D. Holden, K. E. Unsworth, 2001, Infection and Immunity.

Polynucleotide Phosphorylase Negatively Controls spv Virulence Gene Expression in Salmonella enterica

A. Thompson, J. Hinton, D. Holden, 2006, Infection and Immunity.

SsaM and SpiC interact and regulate secretion of Salmonella Pathogenicity Island 2 type III secretion system effectors and translocators

Mei Liu, D. Holden, Xiu-jun Yu, 2004, Molecular microbiology.

Inhibition of Nuclear Transport of NF-ĸB p65 by the Salmonella Type III Secretion System Effector SpvD

Mei Liu, D. Holden, Nathalie Rolhion, 2016, PLoS pathogens.

Microtubule motors control membrane dynamics of Salmonella-containing vacuoles

E. Caron, C. Bucci, C. Beuzón, 2004, Journal of Cell Science.

A role for the PhoP/Q regulon in inhibition of fusion between lysosomes and Salmonella‐containing vacuoles in macrophages

C. Beuzón, D. Holden, S. Garvis, 2001, Cellular microbiology.

Remodelling of the actin cytoskeleton is essential for replication of intravacuolar Salmonella

M. Martínez-Lorenzo, G. Griffiths, J. Gorvel, 2001, Cellular microbiology.

Virulence Serovar Typhimurium Salmonella enterica System Contribute Independently to Pathogenicity Island 2 Type III Secretion Salmonella PhoP-PhoQ and the In Vivo Genetic Analysis Indicates That

C. Beuzón, D. Holden, K. E. Unsworth, 2001 .

Mutations in Salmonella Pathogenicity Island 2 (SPI2) Genes Affecting Transcription of SPI1 Genes and Resistance to Antimicrobial Agents

M. Hensel, D. Holden, T. Nikolaus, 1998, Journal of bacteriology.

Contribution of the PhoP/Q regulon to survival and replication of Salmonella enterica serovar Typhimurium in macrophages

Jessica A. Thompson, Mei Liu, D. Holden, 2011, Microbiology.

Tandem Translation Generates a Chaperone for the Salmonella Type III Secretion System Protein SsaQ*

Mei Liu, D. Holden, S. Matthews, 2011, The Journal of Biological Chemistry.

The interplay between Salmonella typhimurium and its macrophage host--what can it teach us about innate immunity?

D. Holden, S. Linehan, 2003, Immunology letters.

Salmonella regulates polyubiquitination and surface expression of MHC class II antigens

Des C. Jones, J. Trowsdale, S. Méresse, 2009, Proceedings of the National Academy of Sciences.

SseK1 and SseK3 Type III Secretion System Effectors Inhibit NF-κB Signaling and Necroptotic Cell Death in Salmonella-Infected Macrophages

D. Holden, S. Matthews, Teresa L. M. Thurston, 2017, Infection and Immunity.

The Salmonella Effector SpvD Is a Cysteine Hydrolase with a Serovar-specific Polymorphism Influencing Catalytic Activity, Suppression of Immune Responses, and Bacterial Virulence

J. Pruneda, D. Komander, S. Hare, 2016, The Journal of Biological Chemistry.

The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases

Balaji Santhanam, H. Ovaa, J. Pruneda, 2016, Molecular cell.

The DUB-ious lack of ALIS in Salmonella infection

Mair E. M. Thomas, D. Holden, F. Mesquita, 2012, Autophagy.

The influence of the Ustilago maydis REC1 gene on plasmid-chromosome recombination

N. Kanuga, A. Spanos, D. Holden, 1992, Current Genetics.

Nck and Cdc42 co-operate to recruit N-WASP to promote Fc&ggr;R-mediated phagocytosis

E. Caron, M. Way, D. Holden, 2012, Journal of Cell Science.

Elucidating population-wide mycobacterial replication dynamics at the single-cell level

D. Holden, S. Sampson, S. Helaine, 2016, Microbiology.

To establish whether alpha/gamma enolase, a putative autoantigen, plays a role in the pathogenesis of antibasal ganglia antibody (ABGA) associated disorders

D. Holden, A. Church, Joseph Cohen, 2006 .

A COMMERCIAL EXTRACT OF THE BROWN SEAWEED ASCOPHYLLUM NODOSUM SUPPRESSES AVOCADO THRIPS AND PERSEA MITES IN FIELD-GROWN 'HASS' AVOCADOS, A PRACTICAL FIELD PERSPECTIVE

D. Holden, R. Ross, 2013 .

A Rab 32-Dependent Pathway Contributes to Salmonella Typhi Host Restriction

L. J. Mota, D. Holden, L. Pinaud, 2012 .

Additive Inhibition of Complement Deposition by Pneumolysin and PspA Facilitates Streptococcus pneumoniae Septicemia 1

Jeremy S. Brown, D. Holden, M. Botto, 2005, The Journal of Immunology.

Identification and analysis of bacterial virulence genes in vivo.

D. Holden, K. E. Unsworth, Kate E. Unsworth, 2000, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Structure of the cytoplasmic domain of SctV (SsaV) from the Salmonella SPI-2 injectisome and implications for a pH sensing mechanism

P. Rosenthal, M. Beeby, S. Rouse, 2021, Journal of structural biology.

Molecular genetics ofAspergillus pathogenicity

D. Holden, C. Tang, Joanne M. Smith, 2004, Antonie van Leeuwenhoek.

Bacterial interactions with the eukaryotic secretory pathway.

D. Holden, S. Salcedo, 2005, Current opinion in microbiology.

Persisters unmasked

D. Holden, 2015, Science.

Six years of strawberry trials in commercial fields demonstrate that an extract of the brown seaweed Ascophyllum nodosum improves yield of strawberries

D. Holden, R. Ross, 2017 .

Nucleotide sequence of the REC1 gene of Ustilago maydis.

A. Spanos, D. Holden, G. Banks, 1989, Nucleic acids research.

Comparison of Virulence between Clinical and Environmental Isolates of Aspergillus fumigatus

D. Holden, J. S. Brown, A. Aufauvre‐Brown, 1998, European Journal of Clinical Microbiology and Infectious Diseases.

Correction for Günster et al., “SseK1 and SseK3 Type III Secretion System Effectors Inhibit NF-κB Signaling and Necroptotic Cell Death in Salmonella-Infected Macrophages”