K. Hodel

发表

The DØ detector

J. S. Hoftun, Terece L. Turton, P. R. Vishwanath, 1994 .

Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair

Z. Pursell, B. Campbell, Nicholas Light, 2018, eLife.

POLE Mutation Spectra Are Shaped by the Mutant Allele Identity, Its Abundance, and Mismatch Repair Status.

Z. Pursell, Z. Suo, Hua Lu, 2020, Molecular cell.

DNA polymerase and mismatch repair exert distinct microsatellite instability signatures in normal and malignant human cells.

G. Getz, K. Cole, T. Kunkel, 2020, Cancer discovery.

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers

Roland Arnold, Richard G Grundy, Daniele Merico, 2015, Nature Genetics.

Comprehensive Analysis of Hypermutation in Human Cancer

K. Cole, P. Raman, C. Hawkins, 2017, Cell.

Cancers from Novel Pole-Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenesis and Immune Checkpoint Blockade

C. Hawkins, Alberto Martin, Z. Pursell, 2020, Cancer Research.

Mouse model and human patient data reveal critical roles for Pten and p53 in suppressing POLE mutant tumor development

Z. Pursell, J. Jackson, K. Hodel, 2022, NAR cancer.

Mouse model and human patient data suggest critical roles for Pten and p53 in suppressing POLE mutant tumor development

Z. Pursell, J. Jackson, K. Hodel, 2021, bioRxiv.

Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair

Z. Pursell, Nicholas Light, A. Shlien, 2018, eLife.

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers

S. Scherer, D. Merico, P. Nathan, 2015, Nature Genetics.