J. Scholten

发表

A protein radical cage slows photolysis of methylcobalamin in methionine synthase from Escherichia coli.

R. Matthews, J. Jarrett, C. Drennan, 1996, Bioorganic & medicinal chemistry.

Protein prenylation: from discovery to prospects for cancer treatment.

M. Gelb, J. Sebolt-Leopold, J. Scholten, 1998, Current opinion in chemical biology.

Novel enzymic hydrolytic dehalogenation of a chlorinated aromatic.

P. Babbitt, D. Dunaway-Mariano, K. H. Chang, 1991, Science.

A synthetic module for the metH gene permits facile mutagenesis of the cobalamin-binding region of Escherichia coli methionine synthase: initial characterization of seven mutant proteins.

R. Matthews, J. Jarrett, C. Drennan, 1996, Biochemistry.

Mutations in the B12-binding region of methionine synthase: how the protein controls methylcobalamin reactivity.

R. Matthews, J. Jarrett, C. Drennan, 1996, Biochemistry.

Echinacea purpurea root extract inhibits TNF release in response to Pam3Csk4 in a phosphatidylinositol-3-kinase dependent manner.

J. Scholten, D. Fast, J. Balles, 2015, Cellular immunology.

Chinese herbal combination of Epimedium , Drynariae rhizoma , and Salvia miltiorrhiza extracts prevents osteoporosis in ovariectomized rats

Yong-fang, J. Rebhun, J. Scholten, 2017 .

Inhibitors of farnesyl:protein transferase--a possible cancer chemotherapeutic.

D. Hupe, J. Sebolt-Leopold, J. Scholten, 1996, Bioorganic & medicinal chemistry.

Identification of a botanical inhibitor of intestinal diacylglyceride acyltransferase 1 activity via in vitro screening and a parallel, randomized, blinded, placebo-controlled clinical trial

J. Scholten, R. A. Velliquette, J. Patterson, 2015, Nutrition & Metabolism.

Bioactivity-Guided Identification of Botanical Inhibitors of Ketohexokinase

M. Lanaspa, C. Rivard, J. Scholten, 2015, PloS one.

Flavanones common to citrus fruits activate the interferon-stimulated response element by stimulating expression of IRF7

Yingqin Li, J. Scholten, Chun Hu, 2019, Journal of Food Bioactives.

The cytoprotective benefits of a turmeric, quercetin, and rosemary blend through activation of the oxidative stress pathway

J. Scholten, D. Fast, C. Burns, 2019, Pharmacognosy Magazine.

Isolation and characterization of the three polypeptide components of 4-chlorobenzoate dehalogenase from Pseudomonas sp. strain CBS-3.

D. Dunaway-Mariano, K. H. Chang, J. Scholten, 1992, Biochemistry.

Synergy between Anions and Farnesyldiphosphate Competitive Inhibitors of Farnesyl:Protein Transferase*

D. Hupe, J. Sebolt-Leopold, J. Scholten, 1997, The Journal of Biological Chemistry.

Inhibitory effect of a novel combination of Salvia hispanica (chia) seed and Punica granatum (pomegranate) fruit extracts on melanin production.

J. Scholten, J. Rana, G. Diwakar, 2014, Fitoterapia.

Differential Prenyl Pyrophosphate Binding to Mammalian Protein Geranylgeranyltransferase-I and Protein Farnesyltransferase and Its Consequence on the Specificity of Protein Prenylation*

M. Gelb, J. Scholten, K. Yokoyama, 1997, The Journal of Biological Chemistry.

Novel enzymic hydrolytic dehalogenation of a chlorinated aromatic.

P. Babbitt, D. Dunaway-Mariano, K. H. Chang, 1991, Science.

CI‐1002: A Combined Acetylcholinesterase Inhibitor and Muscarinic Antagonist 1

C. J. Moore, M. Emmerling, J. Scholten, 1995 .

Immunomodulatory effects of Lippia sidoides extract: induction of IL-10 through cAMP and p38 MAPK-dependent mechanisms.

J. Rebhun, J. Scholten, D. Fast, 2015, Journal of medicinal food.

Structure-activity relationships of cysteine-lacking pentapeptide derivatives that inhibit ras farnesyltransferase.

A. Doherty, J. Sebolt-Leopold, J. C. Hodges, 1997, Journal of medicinal chemistry.

Evaluation of Isoprenoid Conformation in Solution and in the Active Site of Protein-Farnesyl Transferase Using Carbon-13 Labeling in Conjunction with Solution- and Solid-State NMR

R. Gibbs, M. Eilers, J. Scholten, 2000 .

Evaluation of selected traditional Chinese medical extracts for bone mineral density maintenance: A mechanistic study

J. Rebhun, J. Scholten, Kelly M Glynn, 2018, Journal of traditional and complementary medicine.

Modification of proteases to esterases for peptide synthesis: methylchymotrypsin

Chi‐Huey Wong, J. Scholten, A. Scott, 1988 .

Inhibition of melanin production by a combination of Siberian larch and pomegranate fruit extracts.

J. Scholten, J. Rana, G. Diwakar, 2012, Fitoterapia.

Inhibition of melanin content by Punicalagins in the super fruit pomegranate (Punica granatum).

J. Scholten, T. Mulder, J. Rana, 2013, Journal of cosmetic science.

C-terminal modifications of histidyl-N-benzylglycinamides to give improved inhibition of Ras farnesyltransferase, cellular activity, and anticancer activity in mice.

A. Doherty, D. Mcnamara, E. Dobrusin, 1997, Journal of medicinal chemistry.

The effects of protein farnesyltransferase inhibitors on trypanosomatids: inhibition of protein farnesylation and cell growth.

K. Stuart, M. Gelb, F. Buckner, 1998, Molecular and biochemical parasitology.

Purification and characterization of the Tetrahymena pyriformis P-C bond forming enzyme phosphoenolpyruvate phosphomutase.

D. Dunaway-Mariano, J. Scholten, E. Bowman, 1990, Biochemistry.

CI-1002, a Novel Anticholinesterase and Muscarinic Antagonist

C. J. Moore, M. Emmerling, J. Scholten, 1995 .

Signalling approaches to inhibition of cellular proliferation

A. Doherty, D. Mcnamara, R. Panek, 2002 .

Screening for pharmacologic inhibitors of amyloid fibril formation.

H. Levine, J. Scholten, 1999, Methods in enzymology.

Ancestry of the 4-chlorobenzoate dehalogenase: analysis of amino acid sequence identities among families of acyl:adenyl ligases, enoyl-CoA hydratases/isomerases, and acyl-CoA thioesterases.

P. Babbitt, G. L. Kenyon, B. Martin, 1992, Biochemistry.

Transient State Kinetic Analysis of the Chemical Intermediates Formed in the Enzymic Dehalogenation of 4-Chlorobenzoyl Coenzyme A

D. Dunaway-Mariano, J. Scholten, P. Liang, 1995 .

High-level expression of rat farnesyl:protein transferase in Escherichia coli as a translationally coupled heterodimer.

C. Fierke, D. Hupe, K. Zimmerman, 1998, Protein expression and purification.

Methyl chymotrypsin catalyzed hydrolyses of specific substrate esters indicate multiple proton catalysis id possible with a modified charge relay triad

F. Raushel, J. Scholten, J. Hogg, 1988 .

Conserved Cysteine and Tryptophan Residues of the Endothelin-converting Enzyme-1 CXAW Motif Are Critical for Protein Maturation and Enzyme Activity*

J. Scholten, K. Ahn, R. Fuller, 2001, The Journal of Biological Chemistry.

In Vitro and In Vivo Effects of a Dual Inhibitor of Acetylcholinesterase and Muscarinic Receptors, CI-1002

C. J. Moore, M. Emmerling, J. Scholten, 1994 .

PD 142676 (CI 1002), a novel anticholinesterase and muscarinic antagonist

C. J. Moore, M. Emmerling, J. Scholten, 1994, Molecular Neurobiology.

Synergistic Activation of the Nrf2-ARE Oxidative Stress Response Pathway by a Combination of Botanical Extracts

Yumei Lin, J. Scholten, J. Patterson, 2016, Planta Medica International Open.

The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases.

R. T. Carroll, Xiaohong Liu, J. Rubin, 2006, Bioorganic & medicinal chemistry letters.

Involvement of the alpha subunit of farnesyl-protein transferase in substrate recognition.

P. Pellicena, W. Miller, J. Scholten, 1996, Biochemistry.