A. Six

发表

From Molecules to Organisms: Towards Multiscale Integrated Models of Biological Systems

P. Bourgine, G. Beslon, F. Ginelli, 2008 .

Preserving the B-Cell Compartment Favors Operational Tolerance in Human Renal Transplantation

F. Barbé-Tuana, J. Kalil, P. Moraes-Vieira, 2012, Molecular medicine.

Characterization of avian T-cell receptor gamma genes.

J. Rast, M. Cooper, A. Six, 1996, Proceedings of the National Academy of Sciences of the United States of America.

The expansion and selection of T cell receptor αβ intestinal intraepithelial T cell clones

A. Cumano, A. Régnault, P. Kourilsky, 1996 .

Phenotypic and Functional Similarity of Gut Intraepithelial and Systemic T Cells in a Teleost Fish1

P. Boudinot, S. Messiaen, A. Benmansour, 2006, The Journal of Immunology.

TCR repertoire dynamics in the pancreatic lymph nodes of non-obese diabetic (NOD) mice at the time of disease initiation.

E. Mariotti-Ferrandiz, P. Cazenave, H. Hall, 2008, Molecular immunology.

Immunodepression and Immunosuppression During Aging

D. Klatzmann, B. Bellier, Hang-Phuong Pham, 2012 .

Contrasted TCRβ Diversity of CD8+ and CD8− T Cells in Rainbow Trout

P. Boudinot, A. Six, Wahiba Chaara, 2013, PloS one.

Teleost Fish Mount Complex Clonal IgM and IgT Responses in Spleen upon Systemic Viral Infection

Véronique Giudicelli, Frédéric Cazals, Olivier Bouchez, 2013, PLoS pathogens.

TCR sequences and tissue distribution discriminate the subsets of naïve and activated/memory Treg cells in mice

Christof von Kalle, Manfred Schmidt, Wahiba Chaara, 2015, European journal of immunology.

T follicular helper and T follicular regulatory cells have different TCR specificity

E. Mariotti-Ferrandiz, D. Klatzmann, J. Faro, 2017, Nature Communications.

The regenerating family member 3 β instigates IL-17A-mediated neutrophil recruitment downstream of NOD1/2 signalling for controlling colonisation resistance independently of microbiota community structure

B. Ryffel, M. Chamaillard, H. Sokol, 2018, Gut.

A conserved sequence in the mouse variable T cell receptor α recombination signal sequence 23‐bp spacer can affect recombination

H. Rammensee, S. Tenzer, O. Schoor, 2004, European Journal of Immunology.

Systems biology in vaccine design

D. Klatzmann, B. Bellier, A. Six, 2012, Microbial biotechnology.

Representativeness and robustness of TCR repertoire diversity assessment by high-throughput sequencing

E. Mariotti-Ferrandiz, D. Klatzmann, A. Six, 2018, bioRxiv.

RepSeq Data Representativeness and Robustness Assessment by Shannon Entropy

E. Mariotti-Ferrandiz, D. Klatzmann, A. Six, 2018, Front. Immunol..

Behçet’s disease physiopathology: a contemporary review

D. Klatzmann, A. Six, P. Cacoub, 2016, Autoimmunity Highlights.

Dynamical and Mechanistic Reconstructive Approaches of T Lymphocyte Dynamics: Using Visual Modeling Languages to Bridge the Gap between Immunologists, Theoreticians, and Programmers

H. Bersini, J. Ganascia, A. Six, 2013, Front. Immunol..

7 Immunodepression and Immunosuppression During Aging

D. Klatzmann, B. Bellier, Hang-Phuong Pham, 2012 .

HIV-Infected Spleens Present Altered Follicular Helper T Cell (Tfh) Subsets and Skewed B Cell Maturation

É. Oksenhendler, A. Samri, B. Autran, 2015, PloS one.

Comparison of Dendritic Cell Activation by Virus-Based Vaccine Delivery Vectors Emphasizes the Transcriptional Downregulation of the Oxidative Phosphorylation Pathway.

D. Klatzmann, O. U. Sezerman, A. Six, 2019, Human gene therapy.

The Tsallis generalized entropy enhances the interpretation of transcriptomics datasets

D. Klatzmann, N. Tchitchek, Hang-Phuong Pham, 2022, PloS one.

OntoContext, a new python package for gene contextualization based on the annotation of biomedical texts

A. Benammar Elgaaied, A. Six, V. Thomas-Vaslin, 2022, bioRxiv.

Diversity, Molecular Characterization and Expression of T Cell Receptor γ in a Teleost Fish, the Sea Bass (Dicentrarchus labrax, L)

R. Reinhardt, M. Lefranc, F. Buonocore, 2012, PloS one.

Quantifying Lymphocyte Division, Methods

J. Hasenauer, D. Klatzmann, B. Bellier, 2013 .

Interleukin-21 modulates Th1 and Th17 responses in giant cell arteritis.

D. Klatzmann, G. Geri, N. Costedoat-Chalumeau, 2012, Arthritis and rheumatism.

A unique CD8(+) T lymphocyte signature in pediatric type 1 diabetes.

P. van Endert, Y. Hamel, A. Hartemann, 2016, Journal of autoimmunity.

Th1 Response and Systemic Treg Deficiency in Inclusion Body Myositis

C. Duyckaerts, D. Klatzmann, T. Maisonobe, 2014, PloS one.

Cutting Edge: CD4-Independent Development of Functional FoxP3+ Regulatory T Cells1

M. Seman, S. L. Le Corre, A. Six, 2009, The Journal of Immunology.

Intraepithelial and Systemic T Cells in a Phenotypic and Functional Similarity of Gut

P. Boudinot, S. Messiaen, A. Benmansour, 2006 .

State-Transition Diagrams for Biologists

Hugues Bersini, David Klatzmann, Adrien Six, 2012, PloS one.

Human thymopoiesis produces polyspecific CD8+ α/β T cells responding to multiple viral antigens

E. Mariotti-Ferrandiz, D. Klatzmann, H. Vié, 2022, bioRxiv.

Endogenous TCR Recombination in TCR Tg Single RAG-Deficient Mice Uncovered by Robust In Vivo T Cell Activation and Selection

A. Louise, A. Six, A. Freitas, 2010, PloS one.

Clinical‐grade preparation of human natural regulatory T‐cells encoding the thymidine kinase suicide gene as a safety gene

D. Klatzmann, Y. Hamel, A. Six, 2008, The journal of gene medicine.

Clinical grade preparation of human natural regulatory T‐cells encoding the thymidine kinase suicide gene as a safety gene: authors' reponse

D. Klatzmann, Y. Hamel, A. Six, 2009, The journal of gene medicine.

Ontogeny of the Immune System: γ/δ and α/β T Cells Migrate from Thymus to the Periphery in Alternating Waves

M. Cooper, O. Vainio, B. Imhof, 1997, The Journal of experimental medicine.

Broadened T-cell Repertoire Diversity in ivIg-treated SLE Patients is Also Related to the Individual Status of Regulatory T-cells

A. Queirós, J. Demengeot, M. Santos, 2012, Journal of Clinical Immunology.

Serum biomarker signature identifies patients with B-cell non-Hodgkin lymphoma associated with cryoglobulinemia vasculitis in chronic HCV infection.

D. Klatzmann, G. Geri, D. Sène, 2014, Autoimmunity reviews.

Microorganisms linked to inflammatory bowel disease-associated dysbiosis differentially impact host physiology in gnotobiotic mice

H. Sokol, M. Moroldo, Hang-Phuong Pham, 2015, The ISME Journal.

T cell receptors and T cell development.

M. Cooper, A. Six, T. Göbel, 1996, Current topics in microbiology and immunology.

A novel strategy for molecular signature discovery based on independent component analysis

Hang Phuong Pham, Nicolas Dérian, Wahiba Chaara, 2014, Int. J. Data Min. Bioinform..

Regulatory T-cell responses to low-dose interleukin-2 in HCV-induced vasculitis.

F. Carrat, D. Klatzmann, F. Joly, 2011, The New England journal of medicine.

Germline genomic structure of the B10.A mouseTcra-V2 gene subfamily

B. Malissen, P. Cazenave, A. Six, 2007, Immunogenetics.

Card9 mediates susceptibility to intestinal pathogens through microbiota modulation and control of bacterial virulence

M. Chamaillard, H. Sokol, Hang-Phuong Pham, 2017, Gut.

Characterization of avian T-cell receptor γ genes

J. Rast, M. Cooper, A. Six, 1996 .

Identification of an endogenous mammary tumor virus involved in the clonal deletion of Vβ2 T cells

P. Cazenave, A. Six, P. Marche, 1993 .

T cell receptor gene deletion circles identify recent thymic emigrants in the peripheral T cell pool.

R. Hockett, M. Cooper, A. Six, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Clonotypic IgH Response against Systemic Viral infection in Pronephros and Spleen of a Teleost Fish

L. Jouneau, E. Mariotti-Ferrandiz, P. Boudinot, 2022, The Journal of Immunology.

Mechanisms of the Natural Reactivity of Lymphocytes from Noninfected Individuals to Membrane-Associated Leishmania infantum Antigens1

K. Dellagi, P. Cazenave, A. Sassi, 2005, The Journal of Immunology.

Behçet’s disease physiopathology: a contemporary review

D. Klatzmann, A. Six, P. Cacoub, 2016, Autoimmunity Highlights.

Regulatory CD4+ CD25+ Foxp3+ T cells expand during experimental Plasmodium infection but do not prevent cerebral malaria.

P. Cazenave, A. Six, A. Vigário, 2007, International journal for parasitology.

Clinical and multi-omics cross-phenotyping of patients with autoimmune and autoinflammatory diseases: the observational TRANSIMMUNOM protocol

Patrice Cacoub, Francis Berenbaum, Eric Vicaut, 2018, BMJ Open.

Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients.

D. Klatzmann, A. Hartemann, T. Malek, 2015, Journal of autoimmunity.

High-resolution repertoire analysis of Tfr and Tfh cells reveals unexpectedly high diversities indicating a bystander activation of follicular T cells

E. Mariotti-Ferrandiz, D. Klatzmann, P. Ritvo, 2017, bioRxiv.

Human thymopoiesis selects unconventional CD8+ α/β T cells that respond to multiple viruses

E. Mariotti-Ferrandiz, D. Klatzmann, Hang-Phuong Pham, 2020 .

A TCRβ Repertoire Signature Can Predict Experimental Cerebral Malaria

E. Mariotti-Ferrandiz, D. Klatzmann, P. Cazenave, 2016, PloS one.

The Astonishing Diversity of Ig Classes and B Cell Repertoires in Teleost Fish

P. Boudinot, S. Fillatreau, A. Six, 2013, Front. Immun..

T cell diversity and TcR repertoires in teleost fish.

M. Lefranc, P. Boudinot, A. Benmansour, 2011, Fish & shellfish immunology.

Epigenetic regulations in the IFNγ signalling pathway: IFNγ-mediated MHC class I upregulation on tumour cells is associated with DNA demethylation of antigen-presenting machinery genes

I. Štěpánek, D. Klatzmann, A. Six, 2014, Oncotarget.

Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T 1 D patients Running head : dose-dependent low dose IL-2 immunoregulation

D. Klatzmann, A. Hartemann, T. Malek, 2017 .

New perspectives for large-scale repertoire analysis of immune receptors.

P. Boudinot, P. Cazenave, A. Benmansour, 2008, Molecular immunology.

A Profound Alteration of Blood TCRB Repertoire Allows Prediction of Cerebral Malaria1

P. Cazenave, A. Six, A. Collette, 2004, The Journal of Immunology.

Marginal zone B cell enrichment and strong follicular B cell reduction correlate with a delayed IgG response in a light chain diversity restricted mouse model

P. Cazenave, A. Six, E. Barbier, 2004, European journal of immunology.

New methods and software tools for high throughput CDR3 spectratyping. Application to T lymphocyte repertoire modifications during experimental malaria.

P. Cazenave, A. Six, A. Collette, 2003, Journal of immunological methods.

The Ig light chain restricted B6.κ-λSEG mouse strain suggests that the IGL locus genomic organization is subject to constant evolution

X. Montagutelli, P. Cazenave, A. Six, 2002, Immunogenetics.

The Past, Present, and Future of Immune Repertoire Biology – The Rise of Next-Generation Repertoire Analysis

Thierry Mora, Aleksandra M. Walczak, Wahiba Chaara, 2013, Front. Immunol..

ISEApeaks: an Excel platform for GeneScan and Immunoscope data retrieval, management and analysis

Adrien Six, A. Collette, A. Six, 2002, Bioinform..

Half of the T‐cell repertoire combinatorial diversity is genetically determined in humans and humanized mice

D. Klatzmann, Hang-Phuong Pham, A. Six, 2012, European journal of immunology.

GeVaDSs – decision support system for novel Genetic Vaccine development process

J. Blazewicz, D. Klatzmann, A. Six, 2012, BMC Bioinformatics.

Restoration of regulatory and effector T cell balance and B cell homeostasis in systemic lupus erythematosus patients through vitamin D supplementation

J. Piette, D. Klatzmann, G. Geri, 2012, Arthritis Research & Therapy.

Origin of Public Memory B Cell Clones in Fish After Antiviral Vaccination

Thierry Mora, Aleksandra M. Walczak, Frédéric Cazals, 2018, Front. Immunol..

Identification of a T cell receptor beta chain variable region, V beta 20, that is differentially expressed in various strains of mice

D. Loh, A. Six, P. Marche, 1991, The Journal of experimental medicine.

Contrasted TCR b Diversity of CD 8 + and CD 8 2 T Cells in Rainbow Trout

P. Boudinot, A. Six, Wahiba Chaara, 2013 .

High-resolution repertoire analysis reveals a major bystander activation of Tfh and Tfr cells

E. Mariotti-Ferrandiz, D. Klatzmann, P. Ritvo, 2018, Proceedings of the National Academy of Sciences.

Early Transcriptome Signatures from Immunized Mouse Dendritic Cells Predict Late Vaccine-Induced T-Cell Responses

Nicolas Dérian, Bertrand Bellier, Hang-Phuong Pham, 2016, PLoS Comput. Biol..

Naive and memory CD4+ T cell subsets can contribute to the generation of human Tfh cells

D. Klatzmann, N. Tchitchek, C. Blanc, 2021, iScience.

From Molecules to Organisms : Towards Multiscale Integrated Models of Biological Systems

P. Bourgine, G. Beslon, F. Ginelli, 2008 .

B. Ryffel, M. Chamaillard, H. Sokol, 2018, Gut.

Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients.

D. Klatzmann, A. Hartemann, T. Malek, 2015, Journal of autoimmunity.

Regulatory T-cell responses to low-dose interleukin-2 in HCV-induced vasculitis.

F. Carrat, D. Klatzmann, F. Joly, 2011, The New England journal of medicine.

GeVaDSs – decision support system for novel Genetic Vaccine development process

Jacek Blazewicz, Pawel Wojciechowski, Marcin Borowski, 2012, BMC Bioinformatics.

The expansion and selection of T cell receptor alpha beta intestinal intraepithelial T cell clones.

A. Cumano, A. Régnault, P. Kourilsky, 1996, European journal of immunology.

Early Transcriptome Signatures from Immunized Mouse Dendritic Cells Predict Late Vaccine-Induced T-Cell Responses

D. Klatzmann, B. Bellier, A. Six, 2016, PLoS Comput. Biol..

Ontogeny of the Immune System: γ/δ and α/β T Cells Migrate from Thymus to the Periphery in Alternating Waves

M. Cooper, O. Vainio, B. Imhof, 1997, The Journal of experimental medicine.

The Artificial Immune Systems Domain: Identifying Progress and Main Contributors Using Publication and Co-Authorship Analyses

Jean-Gabriel Ganascia, Alaa Abi-Haidar, Adrien Six, 2013, ECAL.