J. Starkova

发表

Integrative analysis of transcriptomics and clinical data uncovers the tumor-suppressive activity of MITF in prostate cancer

I. Heřmanová, R. Barrio, A. Carracedo, 2018, Cell Death & Disease.

Experimental therapy with 9-[2-(phosphonomethoxy)ethyl]-2,6-diaminopurine (PMEDAP): origin of resistance.

M. Zapotocky, J. Starkova, J. Hanzalová, 2007, Folia biologica.

Valproic acid triggers differentiation and apoptosis in AML1/ETO-positive leukemic cells specifically.

E. Mejstrikova, J. Starý, J. Trka, 2012, Cancer letters.

Two novel fusion genes, AIF1L‐ETV6 and ABL1‐AIF1L, result together with ETV6‐ABL1 from a single chromosomal rearrangement in acute lymphoblastic leukemia with prenatal origin

J. Lukeš, J. Zuna, J. Starý, 2018, Genes, chromosomes & cancer.

An activating mutation of GNB1 is associated with resistance to tyrosine kinase inhibitors in ETV6-ABL1-positive leukemia

J. Stuchly, V. Kanderova, J. Falkenburg, 2017, Oncogene.

Characterization of leukemias with ETV6-ABL1 fusion

M. Loh, J. Stuchly, C. Mullighan, 2015, Haematologica.

Reply to ‘Upregulation of asparagine synthetase and cell cycle arrest in t(12;21) positive ALL’ by Stams et al

O. Hrusak, J. Trka, J. Starkova, 2005, Leukemia.

Effect of histone deacetylase inhibitors on the cell nucleus and nucleolus of leukemic myeloblasts in vitro - a cytochemical study.

K. Smetana, J. Trka, M. Zapotocky, 2007, Acta histochemica.

Homeobox gene expression in acute myeloid leukemia is linked to typical underlying molecular aberrations

M. Fornerod, E. Mejstrikova, J. Starý, 2014, Journal of Hematology & Oncology.

ETV6/RUNX1 (TEL/AML1) is a frequent prenatal first hit in childhood leukemia.

O. Hrusak, J. Zuna, Z. Zemanová, 2011, Blood.

Low expression of asparagine synthetase in lymphoid blasts precludes its role in sensitivity to L-asparaginase.

I. Heřmanová, J. Trka, J. Starkova, 2012, Experimental hematology.

Identification of Fusion Gene Breakpoints is Feasible and Facilitates Accurate Sensitive Minimal Residual Disease Monitoring on Genomic Level in Patients With PML-RARA, CBFB-MYH11, and RUNX1-RUNX1T1

J. Lukeš, J. Zuna, J. Starý, 2020, HemaSphere.

Distinct bilineal leukemia immunophenotypes are not genetically determined.

E. Mejstrikova, J. Stuchly, O. Hrusak, 2016, Blood.

Frequency and prognostic impact of ZEB2 H1038 and Q1072 mutations in childhood B-other acute lymphoblastic leukemia

C. Eckert, J. Lukeš, J. Zuna, 2021 .

Frequency and prognostic impact of ZEB2 H1038 and 1072 mutations in childhood B-other acute lymphoblastic leukemia.

C. Eckert, J. Lukeš, J. Zuna, 2020, Haematologica.

Upregulation of asparagine synthetase fails to avert cell cycle arrest induced by L-asparaginase in TEL/AML1-positive leukaemic cells

O. Hrusak, J. Trka, J. Starkova, 2004, Leukemia.

Metabolic profile of leukemia cells influences treatment efficacy of L-asparaginase

J. Starý, J. Trka, J. Starkova, 2019, BMC Cancer.

Altered Metabolism of Leukemic Cells: New Therapeutic Opportunity.

I. Heřmanová, J. Trka, J. Starkova, 2018, International review of cell and molecular biology.

To the nucleolar density and size in apoptotic human leukemic myeloblasts produced in vitro by Trichostatin A.

K. Smetana, J. Trka, J. Starkova, 2009, European journal of histochemistry : EJH.

Mean diameter of nucleolar bodies in cultured human leukemic myeloblasts is mainly related to the S and G2 phase of the cell cycle.

K. Smetana, J. Trka, J. Starkova, 2007, European journal of histochemistry : EJH.

Integrative analysis of transcriptomics and clinical data uncovers the tumor-suppressive activity of MITF in prostate cancer

I. Heřmanová, R. Barrio, A. Carracedo, 2018, Cell Death & Disease.

Genomic landscape of pediatric B-other acute lymphoblastic leukemia in a consecutive European cohort

J. Stuchly, O. Hrusak, A. Musilová, 2019, Haematologica.

ERG deletions in childhood acute lymphoblastic leukemia with DUX4 rearrangements are mostly polyclonal, prognostically relevant and their detection rate strongly depends on screening method sensitivity

E. Mejstrikova, J. Stuchly, A. Musilová, 2019, Haematologica.

Intragenic ERG Deletions Do Not Explain the Biology of ERG-Related Acute Lymphoblastic Leukemia

J. Zuna, J. Starý, J. Trka, 2016, PloS one.

CD2-positive B-cell precursor acute lymphoblastic leukemia with an early switch to the monocytic lineage

T. Kalina, E. Mejstrikova, L. Slámová, 2014, Leukemia.

CD44 and CD27 delineate B-precursor stages with different recombination status and with an uneven distribution in nonmalignant and malignant hematopoiesis.

T. Kalina, E. Mejstrikova, O. Hrusak, 2007, Tissue antigens.

Chromosome 21 gain is dispensable for transient myeloproliferative disorder driven by a novel GATA1 mutation

E. Mejstrikova, D. Heckl, J. Klusmann, 2020, Leukemia.

Low HOX gene expression in PML-RARα-positive leukemia results from suppressed histone demethylation

A. Musilová, J. Trka, J. Starkova, 2018, Epigenetics.

Transmembrane adaptor protein WBP1L regulates CXCR4 signalling and murine haematopoiesis

V. Kanderova, M. Tomlinson, K. Kwiatkowska, 2019, Journal of cellular and molecular medicine.

HOX gene expression in phenotypic and genotypic subgroups and low HOXA gene expression as an adverse prognostic factor in pediatric ALL

E. Mejstrikova, J. Trka, H. Drabkin, 2010, Pediatric blood & cancer.

Pharmacological inhibition of fatty-acid oxidation synergistically enhances the effect of l-asparaginase in childhood ALL cells

G. Kroemer, I. Heřmanová, D. Kavan, 2016, Leukemia.

A novel class of ZNF384 aberrations in acute leukemia

J. Stuchly, O. Hrusak, J. Zuna, 2021, Blood advances.

Targeting amino acid metabolism in cancer.

J. Starkova, Kateřina Hložková, Lucie Safrhansova, 2022, International review of cell and molecular biology.

The Identification of (ETV6)/RUNX1-Regulated Genes in Lymphopoiesis Using Histone Deacetylase Inhibitors in ETV6/RUNX1-Positive Lymphoid Leukemic Cells

T. Kalina, O. Hrusak, J. Trka, 2007, Clinical Cancer Research.

Up-regulation of homeodomain genes, DLX1 and DLX2, by FLT3 signaling

Nianxiang Zhang, I. Heřmanová, S. Kornblau, 2011, Haematologica.

PTEN/PI3K/Akt pathway alters sensitivity of T-cell acute lymphoblastic leukemia to l-asparaginase

I. Heřmanová, J. Starý, J. Trka, 2022, Scientific Reports.

Restored biosynthetic pathways induced by MSCs serve as rescue mechanism in leukemia cells after L-asparaginase therapy

I. Heřmanová, D. Kavan, J. Trka, 2022, Blood advances.

Reply to Stams et al

O. Hrusak, J. Trka, J. Starkova, 2005, Leukemia.

Pancreatitis-associated protein as an early marker of asparaginase-associated pancreatitis

I. Heřmanová, J. Lukeš, J. Starý, 2021, Leukemia and Lymphoma.

L-Asparaginase Causes Metabolic Reprogramming in ALL Cells

I. Heřmanová, D. Kavan, A. Carracedo, 2014 .

Low expression of asparagine synthetase in lymphoid blasts precludes its role in sensitivity to L-asparaginase.

I. Heřmanová, J. Trka, J. Starkova, 2012, Experimental hematology.

ETV6/RUNX1 (TEL/AML1) is a frequent prenatal first hit in childhood leukemia.

O. Hrusak, J. Zuna, Z. Zemanová, 2011, Blood.

leukemia ) is a frequent prenatal first hit in childhood TEL/AML1 ( ETV6/RUNX1

O. Hrusak, J. Zuna, Z. Zemanová, 2013 .

Chimeric JAK2 Kinases Trigger Non-uniform Changes of Cellular Metabolism in BCR-ABL1-like Childhood ALL

J. Lukeš, J. Zuna, J. Trka, 2023, HemaSphere.

Rewired glutamate metabolism diminishes cytostatic action of L-asparaginase.

J. Trka, J. Starkova, M. Alberich-Jorda, 2024, Cancer letters.