J. Burbaum

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Synergistic Computational and Experimental Proteomics Approaches for More Accurate Detection of Active Serine Hydrolases in Yeast

Stacy T. Knutson, J. Fetrow, J. A. Di Gennaro, 2004, Molecular & Cellular Proteomics.

A paradigm for drug discovery employing encoded combinatorial libraries.

N. Sigal, J. Reader, J. Baldwin, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Mapping enzyme active sites in complex proteomes.

B. Cravatt, J. Kozarich, J. Burbaum, 2004, Journal of the American Chemical Society.

Structural relationships and the classification of aminoacyl-tRNA synthetases.

P. Schimmel, J. Burbaum, Paul Schimmel, 1991, The Journal of biological chemistry.

ENGINES OF DISCOVERY

J. Burbaum, 1998 .

Chemokine receptor-ligand interactions measured using time-resolved fluorescence.

James Inglese, S. Patel, J. Burbaum, 1998, Biochemistry.

Regulation of calcineurin phosphatase activity and interaction with the FK-506.FK-506 binding protein complex.

R. Kincaid, S. O'keefe, G. Wiederrecht, 1994, The Journal of biological chemistry.

New technologies for high-throughput screening.

J J Burbaum, N H Sigal, N. Sigal, 1997, Current opinion in chemical biology.

Reconstitution of active human calcineurin from recombinant subunits expressed in bacteria.

S. O'keefe, J. Burbaum, P. Cameron, 1995, Protein expression and purification.

High-resolution functional proteomics by active-site peptide profiling.

Baohong Zhang, J. Burbaum, M. Patricelli, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Synthesis of a Small Molecule Combinatorial Library Encoded with Molecular Tags

J. Baldwin, J. Burbaum, M. Ohlmeyer, 1995 .

Evolutionary optimization of the catalytic effectiveness of an enzyme.

J J Burbaum, J. Knowles, R. Raines, 1989, Biochemistry.

Internal thermodynamics of enzymes determined by equilibrium quench: values of Kint for enolase and creatine kinase.

J. Burbaum, J. Knowles, 1989, Biochemistry.

Screening soft materials for their effect on skin barrier function by high throughput experimentation

S. Mitragotri, T. Gowrishankar, Amit Jain, 2005 .

The nature of pyruvate bound to pyruvate kinase as determined by 13C NMR spectroscopy

J. Knowles, J. Burbaum, 1989 .

Ligand-receptor binding measured by laser-scanning imaging.

James Inglese, J. Burbaum, P. Zuck, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Energy and carbon accounting to compare bioenergy crops.

D. Ort, J. Burbaum, Brian Borak, 2013, Current opinion in biotechnology.

Direct visualization of serine hydrolase activities in complex proteomes using fluorescent active site‐directed probes

J. Burbaum, D. K. Giang, M. Patricelli, 2001, Proteomics.

Assembly of a class I tRNA synthetase from products of an artificially split gene.

P. Schimmel, J. Burbaum, 1991, Biochemistry.

Insertion of new sequences into the catalytic domain of an enzyme.

R. Starzyk, P. Schimmel, J. Burbaum, 1989, Biochemistry.

Understanding structural relationships proteins of unsolved three‐dimensional structure

J J Burbaum, R. Starzyk, P. Schimmel, 1990, Proteins.

Improved calcineurin inhibition by yeast FKBP12-drug complexes. Crystallographic and functional analysis.

J J Burbaum, H K Chan, J. W. Becker, 1993, The Journal of biological chemistry.

Amino acid binding by the Class I aminoacyl‐tRNA synthetases: Role for a conserved proline in the signature sequence

P. Schimmel, J. Burbaum, 1992, Protein science : a publication of the Protein Society.

Ultra-High Throughput Screen of Two-Million-Member Combinatorial Compound Collection in a Miniaturized, 1536-Well Assay Format

M Webb, D Dunn, M Orlowski, 2000, Journal of biomolecular screening.

The Evolution of Miniaturized Well Plates

J J Burbaum, J. Burbaum, 2000, Journal of biomolecular screening.

Miniaturization technologies in HTS: how fast, how small, how soon?

Jonathan J. Burbaum, J. Burbaum, 1998 .

Combinatorial Chemistry: Part of the Evolution in Drug Discovery

N. Sigal, J. Baldwin, J. Burbaum, 1999 .

Combinatorial Libraries Encoded with Electrophoric Tags

J. Reader, J. Baldwin, J. Burbaum, 1995, European Journal of Medicinal Chemistry.

Inhibitor focusing: direct selection of drug targets from proteomes using activity-based probes.

J. Rosenblum, J. Burbaum, T. Nomanbhoy, 2003, Assay and drug development technologies.

Proteomics in drug discovery.

J. Burbaum, Jonathan Burbaum, Gabriela M Tobal, 2002, Current opinion in chemical biology.

Stromelysin‐1: Three‐dimensional structure of the inhibited catalytic domain and of the C‐truncated proenzyme

J. Springer, J. Hermes, P. Fitzgerald, 1995, Protein science : a publication of the Protein Society.

Binary encoded small-molecule libraries in drug discovery and optimization

N. Sigal, J. Reader, J. Baldwin, 1995 .

Dynamic transduction of energy and internal equilibria in enzymes: a reexamination of pyruvate kinase

S. Benner, K. Nambiar, J. Stackhouse, 1985 .