Edaire Cheng

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STAT 3 contributes to transformation of Barrett ’ s epithelial cells that express oncogenic Ras in a p 53-independent fashion

R. Odze, A. Zaika, S. Spechler, 2015 .

Mitochondrial STAT3 contributes to transformation of Barrett's epithelial cells that express oncogenic Ras in a p53-independent fashion.

R. Odze, A. Zaika, S. Spechler, 2015, American journal of physiology. Gastrointestinal and liver physiology.

Tissue remodeling in eosinophilic esophagitis.

S. Spechler, R. Souza, Edaire Cheng, 2012, American journal of physiology. Gastrointestinal and liver physiology.

JAK-STAT6 Pathway Inhibitors Block Eotaxin-3 Secretion by Epithelial Cells and Fibroblasts from Esophageal Eosinophilia Patients: Promising Agents to Improve Inflammation and Prevent Fibrosis in EoE

Jason Y. Park, S. Spechler, R. Souza, 2016, PloS one.

Omeprazole blocks eotaxin-3 expression by oesophageal squamous cells from patients with eosinophilic oesophagitis and GORD

S. Spechler, R. Souza, Chunhua Yu, 2012, Gut.

Targeting the intrinsic inflammatory pathway: honokiol exerts proapoptotic effects through STAT3 inhibition in transformed Barrett's cells.

J. Arbiser, S. Spechler, R. Souza, 2012, American journal of physiology. Gastrointestinal and liver physiology.

Eosinophilic esophagitis: current perspectives from diagnosis to management

A. Bellizzi, A. Schoepfer, R. Penagini, 2016, Annals of the New York Academy of Sciences.

Recent discoveries and emerging therapeutics in eosinophilic esophagitis.

Edaire Cheng, A. Goyal, 2016, World journal of gastrointestinal pharmacology and therapeutics.

Deoxycholic acid causes DNA damage while inducing apoptotic resistance through NF-κB activation in benign Barrett's epithelial cells.

S. Spechler, R. Souza, Chunhua Yu, 2011, American journal of physiology. Gastrointestinal and liver physiology.

Aspirin prevents NF-κB activation and CDX2 expression stimulated by acid and bile salts in oesophageal squamous cells of patients with Barrett's oesophagus

R. Bresalier, S. Spechler, R. Souza, 2017, Gut.

In oesophageal squamous cells exposed to acidic bile salt medium, omeprazole inhibits IL-8 expression through effects on nuclear factor-κB and activator protein-1

S. Spechler, R. Souza, Chunhua Yu, 2013, Gut.

Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference.

Kelley E. Capocelli, J. Sheikh, D. Metz, 2018, Gastroenterology.

Eosinophilic esophagitis: interactions with gastroesophageal reflux disease.

S. Spechler, R. Souza, Edaire Cheng, 2014, Gastroenterology clinics of North America.

Proton pump inhibitors for eosinophilic oesophagitis

Edaire Cheng, 2013, Current opinion in gastroenterology.

Relationship of Eosinophilic Esophagitis to Gastroesophageal Reflux

S. Spechler, Edaire Cheng, H. Winter, 2012 .

Proton pump inhibitor-responsive oesophageal eosinophilia: an entity challenging current diagnostic criteria for eosinophilic oesophagitis

A. Bredenoord, A. Schoepfer, A. Straumann, 2015, Gut.

Autocrine VEGF signaling promotes proliferation of neoplastic Barrett's epithelial cells through a PLC-dependent pathway.

S. Spechler, K. Hatanpaa, R. Souza, 2014, Gastroenterology.

New developments in patients with eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERS Symposium at the 2018 American Academy of Allergy, Asthma & Immunology Meeting.

E. Dellon, T. Platts-Mills, S. Aceves, 2018, The Journal of allergy and clinical immunology.

Proton Pump Inhibitors Decrease Eotaxin-3 Expression in the Proximal Esophagus of Children with Esophageal Eosinophilia

Jason Y. Park, S. Spechler, R. Souza, 2014, PloS one.

In oesophageal squamous cells, nitric oxide causes S-nitrosylation of Akt and blocks SOX2 (sex determining region Y-box 2) expression

R. Odze, T. Shimosegawa, S. Spechler, 2015, Gut.

Omeprazole Blocks STAT6 Binding to the Eotaxin-3 Promoter in Eosinophilic Esophagitis Cells

S. Spechler, R. Souza, Chunhua Yu, 2012, PloS one.

NOD-Like Receptor Protein 3 Inflammasome Priming and Activation in Barrett’s Epithelial Cells

S. Spechler, Toshio Watanabe, Y. Fujiwara, 2016, Cellular and molecular gastroenterology and hepatology.

S. Spechler, R. Souza, Chunhua Yu, 2011, American journal of physiology. Gastrointestinal and liver physiology.

Eosinophilic esophagitis, Barrett's esophagus and esophageal neoplasms in the pediatric patient: a narrative review.

Jason Y. Park, K. Dunbar, David M. Troendle, 2020, Translational gastroenterology and hepatology.

Obtaining adequate lamina propria for subepithelial fibrosis evaluation in pediatric eosinophilic esophagitis.

Jason Y. Park, S. Spechler, R. Souza, 2018, Gastrointestinal endoscopy.

Translating New Developments in Eosinophilic Esophagitis Pathogenesis into Clinical Practice

Edaire Cheng, 2015, Current Treatment Options in Gastroenterology.

Hypoxia-inducible factor-2α plays a role in mediating oesophagitis in GORD

R. Odze, S. Spechler, R. Souza, 2016, Gut.

Post‐transplant lymphoproliferative disorder resembling Wilms tumor. Diagnostic dilemma: Renal biopsy or nephrectomy?

L. Klesse, S. Chinnakotla, Edaire Cheng, 2011, Pediatric transplantation.

Esophagitis Dissecans Superficialis in Children

Jason Y. Park, Edaire Cheng, B. Gurram, 2021, Journal of pediatric gastroenterology and nutrition.

In Barrett's esophagus patients and Barrett's cell lines, ursodeoxycholic acid increases antioxidant expression and prevents DNA damage by bile acids.

S. Spechler, R. Souza, Minhu Chen, 2014, American journal of physiology. Gastrointestinal and liver physiology.