Tae-Won Kim

Preclinical evaluation of the toxicological effects of a novel constrained ethyl modified antisense compound targeting signal transducer and activator of transcription 3 in mice and cynomolgus monkeys.

B. Monia, Shin-Young Park, S. Henry, 2013, Nucleic acid therapeutics.

Antisense oligonucleotides on neurobehavior, respiratory, and cardiovascular function, and hERG channel current studies.

Shin-Young Park, S. Henry, Ki-Suk Kim, 2014, Journal of pharmacological and toxicological methods.

Suppressing transthyretin production in mice, monkeys and humans using 2nd-Generation antisense oligonucleotides

M. Benson, Shuling Guo, B. Monia, 2016, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

Cross-Species Pharmacokinetic Comparison from Mouse to Man of a Second-Generation Antisense Oligonucleotide, ISIS 301012, Targeting Human Apolipoprotein B-100

R. Yu, R. Geary, Tanya A Watanabe, 2007, Drug Metabolism and Disposition.

Conjugation of hydrophobic moieties enhances potency of antisense oligonucleotides in the muscle of rodents and non-human primates

F. Rigo, C. Bennett, Tae-Won Kim, 2019, Nucleic acids research.

Comparison of the Class Effects of Antisense Oligonucleotides in CByB6F1-Tg(HRAS)2Jic and CD-1 Mice

S. Henry, J. Matson, S. Burel, 2018, Toxicologic pathology.

Chronic Toxicity Assessment of 2'-O-Methoxyethyl Antisense Oligonucleotides in Mice.

Shin-Young Park, S. Henry, Tae-Won Kim, 2018, Nucleic acid therapeutics.

Toxicologic Properties of 2-O-Methoxyethyl Chimeric Antisense Inhibitors in Animals and Man

A. Levin, S. Henry, Tae-Won Kim, 2007 .

Predictive Dose-Based Estimation of Systemic Exposure Multiples in Mouse and Monkey Relative to Human for Antisense Oligonucleotides With 2′-O-(2-Methoxyethyl) Modifications

S. Henry, R. Yu, R. Geary, 2015, Molecular therapy. Nucleic acids.

Disposition and Pharmacokinetics of a GalNAc3-Conjugated Antisense Oligonucleotide Targeting Human Lipoprotein (a) in Monkeys.

M. Graham, S. Henry, R. Yu, 2016, Nucleic acid therapeutics.