J. Weichert

发表

Genetic ablation of PKC epsilon inhibits prostate cancer development and metastasis in transgenic mouse model of prostate adenocarcinoma.

W. Zhong, A. Verma, B. Hafeez, 2011, Cancer research.

Successful Translation of Fluorescence Navigation During Oncologic Surgery: A Consensus Report

Keith D Paulsen, Alexander L Vahrmeijer, Jason M Warram, 2016, The Journal of Nuclear Medicine.

Regulatory Aspects of Optical Methods and Exogenous Targets for Cancer Detection.

Christopher H Contag, Sanjiv S Gambhir, Brian W Pogue, 2017, Cancer research.

Beyond the margins: real-time detection of cancer using targeted fluorophores

Eben L. Rosenthal, Kevin W. Eliceiri, Jason M. Warram, 2017, Nature Reviews Clinical Oncology.

Preclinical Characterization of 86/90Y-NM600 in a Variety of Murine and Human Cancer Tumor Models

B. Bednarz, J. Engle, R. Hernandez, 2019, The Journal of Nuclear Medicine.

A Surface-Modified Chylomicron Remnant-like Emulsion for Percutaneous Computed Tomography Lymphography: Synthesis and Preliminary Imaging Findings

E. Wisner, R. Counsell, J. Weichert, 2002, Investigative radiology.

Impact of PET and MRI threshold-based tumor volume segmentation on patient-specific targeted radionuclide therapy dosimetry using CLR1404

B. Bednarz, J. Kuo, J. Weichert, 2017, Physics in medicine and biology.

Related Methods for Three-Dimensional Imaging

S. Fraser, J. Tyszka, S. Ruffins, 2006 .

Low-attenuation oral GI contrast agents in abdominal-pelvic computed tomography

T. Winter, J. Weichert, A. Taylor, 2005, Abdominal Imaging.

CT depiction of experimental liver tumors: contrast enhancement with hepatocyte-selective iodinated triglyceride versus conventional techniques.

J. Kuhlman, F. Lee, J. Weichert, 1997, Radiology.

Targeted Molecular Radiotherapy of Pediatric Solid Tumors Using a Radioiodinated Alkyl-Phospholipid Ether Analog

B. Bednarz, Qianqian Zhao, D. Baiu, 2017, The Journal of Nuclear Medicine.

Enhanced Radiosensitivity in Solid Tumors using a Tumor-selective Alkyl Phospholipid Ether Analog

P. Harari, B. Bednarz, Sorabh Singhal, 2018, Molecular Cancer Therapeutics.

Tumor-selective anti-cancer effects of the synthetic alkyl phosphocholine analog CLR1404 in neuroblastoma.

Sorabh Singhal, J. Eickhoff, D. Baiu, 2015, American journal of cancer research.

Improved kinetic analysis of dynamic PET data with optimized HYPR-LR.

Charles A Mistretta, Jamey P Weichert, Bradley T Christian, 2012, Medical physics.

Computed tomography scanning of Morris hepatomas with liver-specific polyiodinated triglycerides.

F. Lee, R. Counsell, J. Weichert, 1996, Academic radiology.

Computed tomography scanning of hepatic tumors with polyiodinated triglycerides.

I. Francis, F. Lee, R. Counsell, 1996, Academic radiology.

Pretreatment CLR 124 Positron Emission Tomography Accurately Predicts CLR 131 Three-Dimensional Dosimetry in a Triple-Negative Breast Cancer Patient.

B. Bednarz, J. Weichert, L. Hall, 2019, Cancer biotherapy & radiopharmaceuticals.

Murine-specific Internal Dosimetry for Preclinical Investigations of Imaging and Therapeutic Agents

B. Bednarz, D. Baiu, M. Otto, 2018, Health physics.

Methoxypoly(ethylene glycol)-conjugated carboxypeptidase A for solid tumor targeting: part II: pharmacokinetics and biodistribution in normal and tumor-bearing rodents.

J. Fine, G. Kwon, Giangthy N. Ton, 2005, Journal of controlled release : official journal of the Controlled Release Society.

Preclinical Pharmacokinetics and Dosimetry Studies of 124I/131I-CLR1404 for Treatment of Pediatric Solid Tumors in Murine Xenograft Models

B. Bednarz, R. Hernandez, D. Baiu, 2019, The Journal of Nuclear Medicine.

pediatric solid tumors in murine xenograft models

B. Bednarz, R. Hernandez, D. Baiu, 2019 .

Formulation of Polyiodinated Triglyceride Analogues in a Chylomicron Remnant-Like Liver-Selective Delivery Vehicle

R. Counsell, J. Weichert, M. Longino, 1996, Pharmaceutical Research.

Next-Generation Cancer Magnetic Resonance Imaging With Tumor-Targeted Alkylphosphocholine Metal Analogs

A. McMillan, A. Audhya, J. Kuo, 2022, Investigative radiology.

Low-Dose Radiation Potentiates the Propagation of Anti-Tumor Immunity against Melanoma Tumor in the Brain after In Situ Vaccination at a Tumor outside the Brain

B. Bednarz, KyungMann Kim, J. Engle, 2021, Radiation Research.

Imaging Efficacy of a Hepatocyte-Selective Polyiodinated Triglyceride for Contrast-Enhanced Computed Tomography

F. Lee, R. Counsell, J. Weichert, 2001, American journal of therapeutics.

Quantification of CLR1401, a novel alkylphosphocholine anticancer agent, in rat plasma by hydrophilic interaction liquid chromatography-tandem mass spectrometric detection.

Giangthy N. Ton, J. Weichert, Hongliang Jiang, 2010, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Lipid-based blood-pool CT imaging of the liver.

F. Lee, R. Counsell, J. Weichert, 1998, Academic radiology.

Physicochemical characterization of a synthetic lipid emulsion for hepatocyte-selective delivery of lipophilic compounds: application to polyiodinated triglycerides as contrast agents for computed tomography.

R. Counsell, J. Weichert, M. Longino, 1996, Journal of pharmaceutical sciences.

Radioiodination via isotope exchange in pivalic acid

R. Counsell, J. Weichert, M. P. Groziak, 1986 .

Imaging efficacy of a hepatocyte-selective polyiodinated triglyceride (DHOG-LE) for contrast-enhanced CT.

F. Lee, B. Markhardt, J. Weichert, 2002, Academic radiology.

Hepatobiliary imaging using a novel hepatocyte-selective CT contrast agent.

F. Lee, R. Counsell, J. Weichert, 2002, Academic radiology.

Potential tumor- or organ-imaging agents. 27. Polyiodinated 1,3-disubstituted and 1,2,3-trisubstituted triacylglycerols.

R. Counsell, J. Weichert, M. P. Groziak, 1986, Journal of medicinal chemistry.

Application of a whole-body pharmacokinetic model for targeted radionuclide therapy to NM404 and FLT

R. Jeraj, W. Tomé, Alice Nomura, 2012, Physics in medicine and biology.

Small animal microCT colonography

J. Weichert, R. Halberg, B. Durkee, 2010 .

Virtual MicroCT Angiography with BP20 in Live Mice

F. Lee, J. Weichert, M. Longino, 2005 .

Hybrid PET/CT for noninvasive pharmacokinetic evaluation of dynamic PolyConjugates, a synthetic siRNA delivery system.

J. Wolff, V. Trubetskoy, J. Weichert, 2010, Bioconjugate chemistry.

Mice expressing activated PI3K rapidly develop advanced colon cancer.

M. Washington, D. Deming, J. Weichert, 2012, Cancer research.

[124I]CLR1404 PET/CT in High-Grade Primary and Metastatic Brain Tumors

S. Perlman, J. Kuo, M. Otto, 2019, Molecular Imaging and Biology.

Clinical Imaging and Dosimetry of a Pan-Cancer Targeting Alkylphosphocholine Analog, [124I]I-NM404

Steve Y. Cho, B. Bednarz, J. Kuo, 2022, Radiation.

Profound immunomodulatory effects of 225Ac-NM600 drive enhanced anti-tumor response in prostate cancer

Zachary T. Rosenkrans, D. McNeel, B. Bednarz, 2022, bioRxiv.

PET/CT imaging of the diapeutic alkylphosphocholine analog 124I-CLR1404 in high and low-grade brain tumors.

B. Bednarz, S. Perlman, J. Kuo, 2017, American journal of nuclear medicine and molecular imaging.

Optimizing Flow Cytometric Analysis of Immune Cells in Samples Requiring Cryopreservation from Tumor-Bearing Mice

D. McNeel, KyungMann Kim, R. Hernandez, 2021, The Journal of Immunology.

Cryopreservation from Tumor-Bearing Mice Immune Cells in Samples Requiring Optimizing Flow Cytometric Analysis of

D. McNeel, KyungMann Kim, R. Hernandez, 2021 .

Partial volume correction improves theranostic 124I/131I-CLR1404 tumor dosimetry in xenograft models of head and neck cancer

P. Harari, B. Bednarz, R. Hernandez, 2022, 2202.06423.

A Phase 1, Multi-Center, Open-Label, Dose-Escalation Study of 131I-CLR1404 in Subjects with Relapsed or Refractory Advanced Solid Malignancies

S. Perlman, M. Pishvaian, J. Weichert, 2015, Cancer investigation.

Biodistribution of a new lipid-soluble CT contrast agent. Evaluation of cholesteryl iopanoate in the rabbit.

G. Glazer, R. Counsell, J. Weichert, 1983, Investigative radiology.

Cyclotron-Produced 132La as a PET Imaging Surrogate for Therapeutic 225Ac

J. Engle, T. Barnhart, R. Hernandez, 2020, The Journal of Nuclear Medicine.

Potential tumor- or organ-imaging agents. 26. Polyiodinated 2-substituted triacylglycerols as hepatographic agents.

R. Counsell, J. Weichert, S. Schwendner, 1986, Journal of medicinal chemistry.

Temporal analysis of type 1 interferon activation in tumor cells following external beam radiotherapy or targeted radionuclide therapy

B. Bednarz, KyungMann Kim, J. Engle, 2021, Theranostics.

TITLE: 177Lu-NM600 targeted radionuclide therapy extends survival in syngeneic murine models of triple-negative breast cancer. RUNNING TITLE: TRT of triple-negative breast cancer

J. Engle, R. Hernandez, J. Weichert, 2019 .

Priority Report Mice Expressing Activated PI 3 K Rapidly Develop Advanced Colon Cancer

M. Washington, D. Deming, J. Weichert, 2012 .

Synthesis and structure-activity relationship effects on the tumor avidity of radioiodinated phospholipid ether analogues.

R. Counsell, J. Weichert, M. Gross, 2006, Journal of medicinal chemistry.

Diapeutic cancer-targeting alkylphosphocholine analogs may advance management of brain malignancies.

J. Kuo, Kyle Swanson, J. Weichert, 2016, CNS oncology.

Analysis of Cancer-Targeting Alkylphosphocholine Analogue Permeability Characteristics Using a Human Induced Pluripotent Stem Cell Blood-Brain Barrier Model.

Sean P. Palecek, J. Kuo, S. Palecek, 2016, Molecular pharmaceutics.

Fluorescent cancer-selective alkylphosphocholine analogs for intraoperative glioma detection.

Kyle I Swanson, Jamey P Weichert, Mohammed Farhoud, 2015, Neurosurgery.

Alkylphosphocholine Analogs for Broad-Spectrum Cancer Imaging and Therapy

P. Pickhardt, J. Kuo, Kyle Swanson, 2014, Science Translational Medicine.

mTOR Inhibition Elicits a Dramatic Response in PI3K-Dependent Colon Cancers

M. Washington, D. Deming, J. Weichert, 2013, PLoS ONE.

A target-selected Apc-mutant rat kindred enhances the modeling of familial human colon cancer

J. Amos-Landgraf, C. Kendziorski, L. Kwong, 2007, Proceedings of the National Academy of Sciences.

Combined hepatocyte-selective and blood-pool contrast agents for the CT detection of experimental liver tumors in rabbits.

D M Heisey, J E Kuhlman, D. Heisey, 2000, Radiology.

Safety and feasibility of an in situ vaccination and immunomodulatory targeted radionuclide combination immuno-radiotherapy approach in a comparative (companion dog) setting

B. Bednarz, M. Albertini, J. Engle, 2021, PloS one.

Developments in Combining Targeted Radionuclide Therapies and Immunotherapies for Cancer Treatment

R. Hernandez, J. Weichert, J. Grudzinski, 2022, Pharmaceutics.

Prostate Cancer Cells Express More Androgen Receptor (AR) Following Androgen Deprivation, Improving Recognition by AR-Specific T Cells

C. Drake, D. McNeel, L. Ellis, 2017, Cancer Immunology Research.

Low-dose targeted radionuclide therapy renders immunologically cold tumors responsive to immune checkpoint blockade

Amy K. Erbe, B. Bednarz, KyungMann Kim, 2021, Science Translational Medicine.

Effect of Polar Head Group Modifications on the Tumor Retention of Phospholipid Ether Analogs: Role of the Quaternary Nitrogen

R. Counsell, J. Weichert, A. Pinchuk, 2023, Pharmaceutics.

Synthesis and biological evaluation of radioiodinated phospholipid ether stereoisomers.

R. Wahl, S. Fisher, R. Counsell, 1995, Journal of Medicinal Chemistry.

Radiation to all macroscopic sites of tumor permits greater systemic antitumor response to in situ vaccination

Amy K. Erbe, B. Bednarz, R. Hernandez, 2023, Journal for ImmunoTherapy of Cancer.

MicroPET/CT colonoscopy in long-lived Min mouse using NM404

Matthew B. Christensen, Richard B. Halberg, Melissa M. Schutten, 2009, Medical Imaging.

Positron emission tomography assessment of 8-OH-DPAT-mediated changes in an index of cerebral glucose metabolism in female marmosets

Ian J. Rowland, Alexander K. Converse, David H. Abbott, 2012, NeuroImage.

PIK3CA and APC mutations are synergistic in the development of intestinal cancers

M. Washington, D. Deming, J. Weichert, 2014, Oncogene.

Microcomputed tomography colonography for polyp detection in an in vivo mouse tumor model.

Perry J Pickhardt, Jason Fine, Jamey P Weichert, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Antitumor efficacy of 90Y-NM600 targeted radionuclide therapy and PD-1 blockade is limited by regulatory T cells in murine prostate tumors

D. McNeel, B. Bednarz, J. Engle, 2022, Journal for ImmunoTherapy of Cancer.

Imaging of murine liver tumor using microCT with a hepatocyte-selective contrast agent: accuracy is dependent on adequate contrast enhancement.

Jamey P Weichert, Chen Qi, F. Lee, 2004, The Journal of surgical research.

In vivo cancer imaging by poly(ethylene glycol)-b-poly(ɛ-caprolactone) micelles containing a near-infrared probe.

Ho-Chul Shin, G. Kwon, G. Indig, 2012, Nanomedicine : nanotechnology, biology, and medicine.

Micro–Computed Tomography of Mouse Cancer Models

Jamey P. Weichert, J. Weichert, 2004 .

Measurement of Iodine-131 volatility during an evaporation process

J. Weichert, L. Trembath, N. Fleck, 2008 .

Using trends in electronic recordings of vital signs to identify patients stable for transfer from acute hospitals.

C. Subbe, B. Duller, J. Weichert, 2019, Acute medicine.

A radiobiological model of metastatic burden reduction for molecular radiotherapy: application to patients with bone metastases

Jian Z. Wang, R. Stewart, W. Tomé, 2017 .

Dosimetric effectiveness of targeted radionuclide therapy based on a pharmacokinetic landscape.

R. Jeraj, J. Weichert, J. Grudzinski, 2010, Cancer biotherapy & radiopharmaceuticals.

Polyiodinated triglyceride lipid emulsions for use as hepatoselective contrast agents in CT: effects of physicochemical properties on biodistribution and imaging profiles.

R. Counsell, J. Weichert, M. Longino, 2000, Investigative radiology.

Polyiodinated triglyceride analogs as potential computed tomography imaging agents for the liver.

R. Counsell, J. Weichert, S. Schwendner, 1995, Journal of medicinal chemistry.

Therapeutic combination of radiolabeled CLR1404 with external beam radiation in head and neck cancer model systems.

P. Harari, B. Bednarz, R. Kimple, 2015, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Longitudinal assessment of colonic tumor fate in mice by computed tomography and optical colonoscopy.

M. Newton, K. Shinki, J. Weichert, 2009, Academic radiology.

The biological effectiveness of targeted radionuclide therapy based on a whole-body pharmacokinetic model

R. Jeraj, W. Tomé, J. Weichert, 2010, Physics in medicine and biology.

177Lu-NM600 Targeted Radionuclide Therapy Extends Survival in Syngeneic Murine Models of Triple-Negative Breast Cancer

J. Engle, R. Hernandez, J. Weichert, 2019, The Journal of Nuclear Medicine.

Phospholipid Ether Analogs for the Detection of Colorectal Tumors

Richard B. Halberg, Jamey P. Weichert, M. Washington, 2014, PloS one.

Patient specific treatment planning for systemically administered radiopharmaceuticals using PET/CT and Monte Carlo simulation.

P. Deluca, J. Weichert, H Yoriyaz, 2010, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

90Y-NM600 targeted radionuclide therapy induces immunologic memory in syngeneic models of T-cell Non-Hodgkin’s Lymphoma

J. Engle, R. Hernandez, J. Weichert, 2019, Communications Biology.

Potential tumor- or organ-imaging agents. 23. Sterol esters of iopanoic acid.

R. Counsell, J. Weichert, M. P. Groziak, 1982, Journal of Medicinal Chemistry.

Radioiodinated Cholesteryl lopanoate as a Potential Probe for the in Vivo Visualization of Atherosclerotic Lesions in Animals

R. Counsell, J. Weichert, S. Schwendner, 1986, Pharmaceutical Research.

POTENTIAL TUMOR- OR ORGAN-IMAGING AGENTS. 23. STEROL ESTERS OF IOPANOIC ACID

R. Counsell, J. Weichert, M. P. Groziak, 1983 .

Analysis of Cancer-targeting Alkylphosphocholine Analog Permeability Characteristics Using a Human Induced Pluripotent Stem Cell Blood-Brain Barrier Model

Sean P. Palecek, J. Kuo, E. Shusta, 2016 .

Targeting of Head and Neck Cancer by Radioiodinated CLR1404 in Murine Xenograft Tumor Models with Partial Volume Corrected Theranostic Dosimetry.

P. Harari, B. Bednarz, R. Hernandez, 2023, Cancer biotherapy & radiopharmaceuticals.

Theranostic Combination of Molecularly Targeted Radiotherapy and Immunotherapy Optimizes Therapeutic Response in a Syngeneic Murine Model of Melanoma

B. Bednarz, S. Gillies, R. Hernandez, 2018 .

Myeloid-derived suppressor cells attenuate the antitumor efficacy of radiopharmaceutical therapy using 90Y-NM600 in combination with androgen deprivation therapy in murine prostate tumors

D. McNeel, J. Weichert, Anusha Muralidhar, 2024, Journal for ImmunoTherapy of Cancer.

Comparative Study of the Effect of Radiation Delivered by Lutetium-177 or Actinium-225 on Anti-GD2 Chimeric Antigen Receptor T Cell Viability and Functions

Q. Sodji, J. Weichert, C. Capitini, 2023, Cancers.

Small animal micro-CT colonography.

Benjamin Y Durkee, Jamey P Weichert, Richard B Halberg, 2010, Methods.

A Phase 1, Multi-Center, Open-Label, Dose-Escalation Study of 131I-CLR1404 in Subjects with Relapsed or Refractory Advanced Solid Malignancies

S. Perlman, M. Pishvaian, J. Weichert, 2015, Cancer investigation.

A Phase 1 Study of 131I-CLR1404 in Patients with Relapsed or Refractory Advanced Solid Tumors: Dosimetry, Biodistribution, Pharmacokinetics, and Safety

Steve Y. Cho, J. Marshall, J. Weichert, 2014, PloS one.

Reproducibility of tumor volume measurement at microCT colonography in living mice.

M. Newton, P. Pickhardt, J. Weichert, 2008, Academic radiology.