A. Sirén

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Erythropoietin and erythropoietin receptor in human ischemic/hypoxic brain

W. Brück, H. Ehrenreich, A. Sirén, 2001, Acta Neuropathologica.

Central cardiovascular effects of the endoperoxide analogue U-46619 in rats.

A. Sirén, M. Svartström-Fraser, I. Paakkari, 1985, Prostaglandins, leukotrienes, and medicine.

Global Forebrain Ischemia Results in Differential Cellular Expression of Interleukin-1β (IL-1β) and its Receptor at mRNA and Protein Level

T. Sairanen, A. Sirén, Michaela Brenner, 1997, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Melatonin as a candidate compound for neuroprotection in amyotrophic lateral sclerosis (ALS): high tolerability of daily oral melatonin administration in ALS patients

H. Ehrenreich, M. Bähr, Jochen H Weishaupt, 2002, Journal of pineal research.

Interleukin‐1β mRNA Expression in Ischemic Rat Cortex

P. Young, P. Mcdonnell, F. Barone, 1993 .

Interleukin-1 beta mRNA expression in ischemic rat cortex.

P. Young, P. Mcdonnell, F. Barone, 1993, Stroke.

Prolonged Expression of Interferon‐Inducible Protein‐10 in Ischemic Cortex After Permanent Occlusion of the Middle Cerebral Artery in Rat

T. Yue, J. Ellison, F. Barone, 1998, Journal of neurochemistry.

Temporal profile of expression and cellular localization of inducible nitric oxide synthase, interleukin-1beta and interleukin converting enzyme after cryogenic lesion of the rat parietal cortex.

H. Ehrenreich, A. Sirén, F. Knerlich, 1999, Brain research. Molecular brain research.

Hemodynamic and Neural Mechanisms of Action of Thyrotropin‐Releasing Hormone in the Rat

G. Feuerstein, A. Sirén, C. Lake, 1988, Circulation research.

Cardiovascular pharmacology of thyrotropin releasing hormone

A. Sirén, 1988, Peptides.

Central Autonomic Pharmacology of Thyrotropin Releasing Hormone

G. Feuerstein, A. Sirén, 1987 .

Targeted volumetric single-molecule localization microscopy of defined presynaptic structures in brain sections

M. Sauer, Sven Proppert, Martin Pauli, 2019, Communications Biology.

Survival of hippocampal neurons in culture upon hypoxia: effect of erythropoietin

P. Lewczuk, H. Ehrenreich, M. Hasselblatt, 2000, Neuroreport.

Erythropoietin for Treatment of Human Brain Disease: Experience from Proof-of-Concept Trials

H. Ehrenreich, A. Sirén, 2006 .

Upregulation of intercellular adhesion molecule 1 (ICAM-1) on brain microvascular endothelial cells in rat ischemic cortex.

T. Yue, F. Barone, G. Feuerstein, 1994, Brain research. Molecular brain research.

Preexisting Serum Autoantibodies Against the NMDAR Subunit NR1 Modulate Evolution of Lesion Size in Acute Ischemic Stroke

J. Wiltfang, E. Dere, H. Ehrenreich, 2015, Stroke.

C1-Inhibitor protects from focal brain trauma in a cortical cryolesion mice model by reducing thrombo-inflammation

S. Meuth, A. Sirén, C. Kleinschnitz, 2014, Front. Cell. Neurosci..

Amelioration of Cognitive and Behavioral Deficits after Traumatic Brain Injury in Coagulation Factor XII Deficient Mice

A. Sirén, C. Kleinschnitz, C. Stetter, 2021, International journal of molecular sciences.

Neuroprotective Strategies in Aneurysmal Subarachnoid Hemorrhage (aSAH)

A. Sirén, T. Westermaier, E. Kunze, 2021, International journal of molecular sciences.

Brain Trauma

H. Ehrenreich, H. Krampe, A. Sirén, 2020, The Wiley International Handbook on Psychopathic Disorders and the Law.

Differential Expression of HSC73 and HSP72 mRNA and Proteins between Young and Adult Gerbils after Transient Cerebral Ischemia: Relation to Neuronal Vulnerability

R. McCarron, A. Sirén, M. Spatz, 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

A goldfish model for evaluation of the neurotoxicity of omega-conotoxin GVI A and screening of monoclonal antibodies.

G. Feuerstein, H. Pollard, A. Sirén, 1991, Toxicology and applied pharmacology.

Reduced oxidative damage in ALS by high‐dose enteral melatonin treatment

K. Nave, S. Sperling, H. Ehrenreich, 2006, Journal of pineal research.

Differential cellular expression of tumor necrosis factor-α and Type I tumor necrosis factor receptor after transient global forebrain ischemia

T. Sairanen, O. Carpén, A. Sirén, 2001, Journal of the Neurological Sciences.

Soccer, neurotrauma and amyotrophic lateral sclerosis: is there a connection?

H. Ehrenreich, A. Sirén, O. Piazza, 2004, Current medical research and opinion.

Evidence for activation of endothelium and monocytes in hypertensive rats.

R. McCarron, G. Feuerstein, J. Hallenbeck, 1996, The American journal of physiology.

Mesenteric vascular responses to i.v. administration of lipoxin A4 and lipoxin B4 in the conscious rat

G. Feuerstein, A. Sirén, 1988, FEBS letters.

Dissociation of the cardiovascular and prolactin-releasing activities of norvaline2-TRH

G. Feuerstein, A. Sirén, L. Cohen, 1987, Neuropeptides.

Effect of thyrotropin releasing hormone and some of its histidine analogs on the cardiovascular system and prolactin release in the conscious rat

G. Feuerstein, A. Sirén, L. Cohen, 1986, Neuropeptides.

The Brain Erythropoietin System and its Potential for Therapeutic Exploitation in Brain Disease

H. Ehrenreich, M. Hasselblatt, A. Sirén, 2006, Journal of neurosurgical anesthesiology.

Adhesion Molecules on Normotensive and Hypertensive Rat Brain Endothelial Cells

R. McCarron, J. Hallenbeck, A. Sirén, 1994, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Endothelin converting enzyme activity in primary rat astrocytes is modulated by endothelin B receptors.

H. Ehrenreich, M. Hasselblatt, H. Langen, 1999, Biochemical and biophysical research communications.

A novel role for an established player: anemia drug erythropoietin for the treatment of cerebral hypoxia/ischemia.

H. Ehrenreich, A. Sirén, Wiebke Timner, 2004, Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis.

Release of Proinflammatory and Prothrombotic Mediators in the Brain and Peripheral Circulation in Spontaneously Hypertensive and Normotensive Wistar‐Kyoto Rats

T. Yue, G. Feuerstein, J. Hallenbeck, 1992, Stroke.

Stroke risk factors prepare rat brainstem tissues for modified local Shwartzman reaction.

P. Kochanek, G. Feuerstein, J. Hallenbeck, 1988, Stroke.

Dermorphin analog Tyr-D-Arg2-Phe-sarcosine-induced opioid analgesia and respiratory stimulation: the role of mu 1-receptors?

G. Feuerstein, A. Sirén, P. Paakkari, 1993, The Journal of pharmacology and experimental therapeutics.

Respiratory and locomotor stimulation by low doses of dermorphin, a mu1 receptor-mediated effect.

G. Feuerstein, A. Sirén, P. Paakkari, 1990, The Journal of pharmacology and experimental therapeutics.

Heat-Shock Protein and C-fos Expression in Focal Microvascular Brain Damage

J. Hallenbeck, K. Frerichs, T. Nowak, 1996, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Therapeutic potential of erythropoietin and its structural or functional variants in the nervous system

H. Ehrenreich, A. Sirén, C. Bartels, 2011, Neurotherapeutics.

Increased erythropoietin production after myocardial infarction in mice

P. Ghezzi, R. Latini, M. Leist, 2005, Heart.

Differential Glial and Vascular Expression of Endothelins and Their Receptors in Rat Brain after Neurotrauma

H. Ehrenreich, A. Sirén, F. Knerlich, 2000, Neurochemical Research.

Cardiovascular effects of rat calcitonin gene-related peptide in the conscious rat.

G. Feuerstein, A. Sirén, 1988, The Journal of pharmacology and experimental therapeutics.

Effects of PAF and BN 52021 on cardiac function and regional blood flow in conscious rats.

G. Feuerstein, A. Sirén, 1989, The American journal of physiology.

Antagonism of neutrophil adherence in the deteriorating stroke model in rabbits.

G. Feuerstein, J. Hallenbeck, A. Sirén, 1995, Journal of neurosurgery.

Inhibition of Bradykinin Receptor B1 Protects Mice from Focal Brain Injury by Reducing Blood–Brain Barrier Leakage and Inflammation

T. Renné, S. Meuth, G. Stoll, 2010, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Increased Release of Tumor Necrosis Factor‐α Into the Cerebrospinal Fluid and Peripheral Circulation of Aged Rats

G. Feuerstein, J. Hallenbeck, A. Sirén, 1993, Stroke.

Posttraumatic learning deficits correlate with initial trauma severity and chronic cellular reactions after closed head injury in male mice

A. Sirén, C. Stetter, Mila M. Paul, 2021, Experimental Neurology.

How is the formation of microthrombi after traumatic brain injury linked to inflammation?

B. Nieswandt, A. Sirén, C. Kleinschnitz, 2019, Journal of Neuroimmunology.

Cardio-respiratory changes and mortality in the conscious rat induced by (+)- and (+/-)-anatoxin-a.

A. Sirén, O. Adeyemo, O. M. Adeyemo, 1992, Toxicon : official journal of the International Society on Toxinology.

Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIa

A. Sirén, C. Kleinschnitz, M. Nolte, 2017, Journal of Neuroinflammation.

Skull Fractures Induce Neuroinflammation and Worsen Outcomes after Closed Head Injury in Mice

N. Plesnila, A. Sirén, M. Dambrova, 2019, Journal of neurotrauma.

Distinct Ischemic Effects on HSC70, HSP72, and c-fos Expression in Young and Adult Gerbils

R. McCarron, A. Sirén, M. Spatz, 2001 .

Role of the astrocytic ETB receptor in the regulation of extracellular endothelin‐1 during hypoxia

P. Lewczuk, H. Ehrenreich, M. Hasselblatt, 2001, Glia.

Endothelin B receptor-deficient rats as a subtraction model to study the cerebral endothelin system

W. Brück, H. Ehrenreich, J. Herms, 1999, Neuroscience.

Endothelin b receptor deficient transgenic rescue rats: a rescue phenomenon in the brain

M. Yanagisawa, H. Ehrenreich, C. Gariepy, 2004, Neuroscience.

Delayed Loss of ETB Receptor-Mediated Vasorelaxation after Cold Lesion of the Rat Parietal Cortex

H. Ehrenreich, A. Sirén, F. Knerlich, 1998, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Combined [18F]DPA-714 micro-positron emission tomography and autoradiography imaging of microglia activation after closed head injury in mice

A. Buck, A. Sirén, S. Samnick, 2016, Journal of Neuroinflammation.

An experimental protocol for mimicking pathomechanisms of traumatic brain injury in mice

A. Sirén, C. Kleinschnitz, Furat Raslan, 2012, Experimental & Translational Stroke Medicine.

Endothelin B receptor deficiency augments neuronal damage upon exposure to hypoxia–ischemia in vivo

P. Lewczuk, H. Ehrenreich, M. Hasselblatt, 2002, Brain Research.

Hemodynamic effects of endothelin after systemic and central nervous system administration in the conscious rat

G. Feuerstein, A. Sirén, 1989, Neuropeptides.

Cardiovascular effects of anatoxin-A in the conscious rat.

G. Feuerstein, A. Sirén, 1990, Toxicology and applied pharmacology.

Cell Type Specific Signalling by Hematopoietic Growth Factors in Neural Cells

H. Ehrenreich, A. Sirén, A. Samoylenko, 2006, Neurochemical Research.

ETA and ETB Specific Ligands Synergistically Antagonize Endothelin‐1 Binding to an Atypical Endothelin Receptor in Primary Rat Astrocytes

H. Ehrenreich, M. Hasselblatt, A. Sirén, 1998, Journal of neurochemistry.

Microvascular perfusion during focal vasogenic brain edema: a scanning laser fluorescence microscopy study.

J. Hallenbeck, A. Sirén, P. Lindsberg, 1997, Microvascular research.

Journal of Cerebral Blood Flow and Metabolism Quantitation of Perivascular Monocytes and Macrophages around Cerebral Blood Vessels of Hypertensive and Aged Rats

D. Jacobowitz, Yong Liu, R. McCarron, 2022 .

The supraoptic nuclei in vasopressin and hemodynamic responses to hemorrhage in rats.

G. Feuerstein, A. Sirén, R. Zerbe, 1991, Neuroreport.

L‐649,923: An Antagonist of Cardiac and Vascular Leukotriene D4 Receptors

G. Feuerstein, A. Sirén, J. Eimerl, 1989, Journal of cardiovascular pharmacology.

Monocyte adhesion to cerebromicrovascular endothelial cells derived from hypertensive and normotensive rats.

R. McCarron, J. Hallenbeck, A. Sirén, 1994, The American journal of physiology.

Central cardiovascular and thermal effects of prostaglandin E2 in rats.

A. Sirén, 1979, Acta physiologica Scandinavica.

Hippocampal Cannabinoid-1 Receptor Upregulation Upon Endothelin-B Receptor Deficiency: A Neuroprotective Substitution Effect?

H. Ehrenreich, R. Mechoulam, A. Sirén, 2005, Neurochemical Research.

Phenotype and Stability of Neural Differentiation of Androgenetic Murine ES Cell-Derived Neural Progenitor Cells.

K. Mclaughlin, C. Geis, A. Müller, 2013, Cell medicine.

Cardioventilator effects of TRH in anaesthetized rats: role of the brain stem.

M. Nurminen, A. Sirén, I. Paakkari, 1986, European journal of pharmacology.

Essential role for Stat5 in the neurotrophic but not in the neuroprotective effect of erythropoietin

L. Hennighausen, H. Ehrenreich, A. Sirén, 2008, Cell Death and Differentiation.

Differences in the central actions of arachidonic acid and prostaglandin F2 alpha between spontaneously hypertensive and normotensive rats.

A. Sirén, 1982, Life sciences.

Cytotoxic effects and tolerability of gemcitabine and axitinib in a xenograft model for c-myc amplified medulloblastoma

E. Miele, I. Caruana, Z. Mokhtari, 2021, Scientific Reports.

Proinflammatory Cytokine Expression Contributes to Brain Injury Provoked By Chronic Monocyte Activation

R. McCarron, David A. Martin, J. Hallenbeck, 2001, Molecular medicine.

Respiratory μ-opioid and benzodiazepine interactions in the unrestrained rat

G. Feuerstein, A. Sirén, P. Paakkari, 1993, Neuropharmacology.

Ischemic stroke and traumatic brain injury: The role of the kallikrein–kinin system

A. Sirén, C. Kleinschnitz, C. Albert‐Weissenberger, 2013, Progress in Neurobiology.

Uncoupling of neurodegeneration and gliosis in a murine model of juvenile cortical lesion

S. Sperling, H. Ehrenreich, A. Sirén, 2009, Glia.

Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress

P. Lewczuk, P. Ghezzi, R. Heumann, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Targeting coagulation factor XII as a novel therapeutic option in brain trauma

I. Alafuzoff, N. Marklund, B. Nieswandt, 2016, Annals of neurology.

Erythropoietin Therapy for Acute Stroke Is Both Safe and Beneficial

P. Lewczuk, E. Rüther, O. Gefeller, 2002, Molecular medicine.

The opioid system in cardiac and vascular regulation of normal and hypertensive states.

G. Feuerstein, A. Sirén, 1987, Circulation.

Exploring recombinant human erythropoietin in chronic progressive multiple sclerosis.

W. Paulus, K. Nave, R. Gold, 2007, Brain : a journal of neurology.

Erythropoietin: Novel Approaches to Neuroprotection in Human Brain Disease

M. Herrmann, H. Ehrenreich, H. Krampe, 2004, Metabolic Brain Disease.

Erythropoietin – a novel concept for neuroprotection

H. Ehrenreich, A. Sirén, 2001, European Archives of Psychiatry and Clinical Neuroscience.

Erythropoietin: a multimodal neuroprotective agent

A. Sirén, N. Byts, 2009, Experimental & Translational Stroke Medicine.

Two paternal genomes are compatible with dopaminergic in vitro and in vivo differentiation.

K. Mclaughlin, A. Müller, S. Eckardt, 2010, The International journal of developmental biology.

Chronophin is a glial tumor modifier involved in the regulation of glioblastoma growth and invasiveness

G. Reifenberger, A. Sirén, A. Beilhack, 2016, Oncogene.

Expression patterns of erythropoietin and its receptor in the developing midbrain

S. Washausen, H. Ehrenreich, G. Brunnett, 2004, Anatomy and Embryology.

A hematopoietic growth factor, thrombopoietin, has a proapoptotic role in the brain.

K. Nave, S. Sperling, H. Ehrenreich, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Expression patterns of erythropoietin and its receptor in the developing spinal cord and dorsal root ganglia

H. Ehrenreich, W. Knabe, H. Kuhn, 2005, Anatomy and Embryology.

Blocking of bradykinin receptor B1 protects from focal closed head injury in mice by reducing axonal damage and astroglia activation

S. Meuth, A. Sirén, C. Kleinschnitz, 2012, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Reversal of μ-opioid-mediated respiratory depression by α2-adrenoceptor antagonism

A. Sirén, S. Vonhof, 1991 .

The opioid peptides. A role in hypertension?

G. Feuerstein, A. Sirén, 1987, Hypertension.

Central ventilatory effects of thyrotropin-releasing hormone in the conscious rat

G. Feuerstein, A. Sirén, S. Vonhof, 1991, Neuropeptides.

Erythropoietin: a candidate compound for neuroprotection in schizophrenia

P. Falkai, W. Maier, E. Rüther, 2004, Molecular Psychiatry.

Injection of thyrotropin releasing hormone into the locus coeruleus increases blood pressure.

M. Nurminen, A. Sirén, M. Svartström-Fraser, 1987, European heart journal.

Cardiovascular effects of TRH i.c.v. in conscious rats.

A. Sirén, I. Paakkari, 1984, Clinical and experimental hypertension. Part A, Theory and practice.

Hemodynamic defense response to thyrotropin-releasing hormone injected into medial preoptic nucleus in rats.

G. Feuerstein, A. Sirén, S. Vonhof, 1991, The American journal of physiology.

Effect of morphine on the hemodynamic and neuroendocrine responses to hemorrhage in conscious rats.

D. Goldstein, G. Feuerstein, A. K. Johnson, 1989, Circulatory shock.

Experimental traumatic brain injury

A. Sirén, Christiane Albert-Weissenberger, Anna-Leena Sirén, 2010, Experimental & Translational Stroke Medicine.

Thrombopoietin inhibits nerve growth factor-induced neuronal differentiation and ERK signalling.

H. Ehrenreich, U. Rapp, K. Rajalingam, 2008, Cellular signalling.

Stiff person syndrome-associated autoantibodies to amphiphysin mediate reduced GABAergic inhibition.

C. Wessig, S. Hallermann, M. Gerlach, 2010, Brain : a journal of neurology.

Human Parthenogenetic Embryonic Stem Cell-Derived Neural Stem Cells Express HLA-G and Show Unique Resistance to NK Cell-Mediated Killing

K. Mclaughlin, J. Wischhusen, A. Müller, 2015, Molecular medicine.

Increased endothelial expression of intercellular adhesion molecule-1 in symptomatic versus asymptomatic human carotid atherosclerotic plaque.

K. Pettigrew, R. McCarron, T. DeGraba, 1998, Stroke.

Functional Neuronal Cells Generated by Human Parthenogenetic Stem Cells

C. Geis, A. Müller, S. Eckardt, 2012, PloS one.

Revisiting adult neurogenesis and the role of erythropoietin for neuronal and oligodendroglial differentiation in the hippocampus

E. Neher, T. Dandekar, E. Dere, 2016, Molecular Psychiatry.

N‐Ac‐Leukotriene E4 Unique Vascular Activity in the Conscious Rat

G. Feuerstein, A. Sirén, G. Letts, 1988 .

Central cardiovascular and thermal effects of prostacyclin in rats.

A. Sirén, 1981, Prostaglandins.

Influence of analgesic antipyretics on the central cardiovascular effects of clonidine in rats.

A. Sirén, H. Karppanen, 1980, Prostaglandins.

Role of the kallikrein–kinin system in traumatic brain injury

A. Sirén, C. Kleinschnitz, S. Hopp, 2014, Front. Cell. Neurosci..

Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIa

A. Sirén, C. Kleinschnitz, M. Nolte, 2017, Journal of Neuroinflammation.

Global brain atrophy after unilateral parietal lesion and its prevention by erythropoietin.

J. Frahm, J. Price, S. Sperling, 2006, Brain : a journal of neurology.

Central cardiovascular and thermal effects of prostaglandin D2 in rats.

A. Sirén, 1982, Prostaglandins, leukotrienes, and medicine.

Impaired sodium excretion, decreased glomerular filtration rate and elevated blood pressure in endothelin receptor type B deficient rats

T. Slowinski, H. Ehrenreich, H. Neumayer, 2001, Journal of Molecular Medicine.

FTY720 does not protect from traumatic brain injury in mice despite reducing posttraumatic inflammation

A. Sirén, C. Kleinschnitz, Michael K. Schuhmann, 2014, Journal of Neuroimmunology.

Loss of ETB-receptor-mediated relaxation in basilar artery after cold lesion of the rat parietal cortex.

H. Ehrenreich, A. Sirén, F. Knerlich, 1999, Advances in Experimental Medicine and Biology.

Effect of endothelin‐1 on astrocytic protein content

C. Giaume, H. Ehrenreich, J. Medina, 2003, Glia.

In vitro Gender Differences in Neuronal Survival on Hypoxia and in 17β-Estradiol-Mediated Neuroprotection

H. Ehrenreich, M. Hasselblatt, N. von Ahsen, 2005, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Neuropsychiatric disease relevance of circulating anti-NMDA receptor autoantibodies depends on blood–brain barrier integrity

G. Spalletta, L. Pardo, K. Nave, 2014, Molecular Psychiatry.

Experimental heart failure causes depression-like behavior together with differential regulation of inflammatory and structural genes in the brain

K. Lesch, G. Ertl, T. Strekalova, 2014, Front. Behav. Neurosci..

Erythropoietin prevents neur cerebral ischemia and metab

P. Lewczuk, P. Ghezzi, R. Heumann, 2016 .

MAY 2004: NEWBORN WITH INTRACRANIAL MASS

C. Sommer, A. Gabelmann, P. Möller, 2004, Brain pathology.

Improvement of cognitive functions in chronic schizophrenic patients by recombinant human erythropoietin

J. Aldenhoff, P. Falkai, W. Maier, 2007, Molecular Psychiatry.

Effect of erythropoietin axotomy-induced apoptosis in rat retinal ganglion cells.

H. Ehrenreich, M. Bähr, Jochen H Weishaupt, 2004, Investigative ophthalmology & visual science.

Effects of Erythropoietin in Murine-Induced Pluripotent Cell-Derived Panneural Progenitor Cells

H. Schöler, C. Geis, H. Ehrenreich, 2013, Molecular Medicine.

The Onset of Postischemic Hypoperfusion in Rats Is Precipitous and May Be Controlled by Local Neurons

G. Feuerstein, J. Hallenbeck, K. Frerichs, 1992, Stroke.

Single-Molecule Localization Microscopy of Presynaptic Active Zones in Drosophila melanogaster after Rapid Cryofixation

Martin Pauli, M. Heckmann, A. Sirén, 2023, International journal of molecular sciences.

Active zone compaction correlates with presynaptic homeostatic potentiation.

J. Eilers, M. Sauer, R. Kittel, 2021, Cell reports.

An experimental protocol for in vivo imaging of neuronal structural plasticity with 2-photon microscopy in mice

B. Nieswandt, M. Heckmann, A. Sirén, 2013, Experimental & Translational Stroke Medicine.

Focal brain trauma in the cryogenic lesion model in mice

A. Sirén, C. Kleinschnitz, R. Ernestus, 2012, Experimental & Translational Stroke Medicine.

Hypothalamic mu-opioid receptors in cardiovascular control: A review

G. Feuerstein, A. Sirén, 1988, Peptides.

Effect of naloxone and morphine on survival of conscious rats after hemorrhage.

G. Feuerstein, A. Sirén, 1986, Circulatory shock.

Assessment of damage from implantation of microdialysis probes in the rat hippocampus with silver degeneration staining

J. Davis, B. Crain, G. Feuerstein, 1990, Neuroscience Letters.

ETA and ETB receptor antagonists synergistically increase extracellular endothelin-1 levels in primary rat astrocyte cultures

H. Ehrenreich, M. Hasselblatt, A. Sirén, 1998, Brain Research.

Neuroprotection – what does it mean? – what means do we have?

H. Ehrenreich, A. Sirén, 2001, European Archives of Psychiatry and Clinical Neuroscience.

Hypothalamic opioid μ-receptors regulate discrete hemodynamic functions in the conscious rat

G. Feuerstein, A. Sirén, 1991, Neuropharmacology.

Volume-dependent spatial distribution of microinjected thyrotropin-releasing hormone (TRH) into the medial preoptic nucleus of the rat: An autoradiographic study

G. Feuerstein, A. Sirén, S. Vonhof, 1990, Neuroscience Letters.

Evidence for differential opioid μ 1- and μ 2-receptor-mediated regulation of heart rate in the conscious rat

G. Feuerstein, A. Sirén, P. Paakkari, 1992, Neuropharmacology.

Mechanisms of central hemodynamic and sympathetic regulation by mu opioid receptors: effects of dermorphin in the conscious rat.

D. Goldstein, G. Feuerstein, A. Sirén, 1989, The Journal of pharmacology and experimental therapeutics.

Impact of a Femoral Fracture on Outcome after Traumatic Brain Injury—A Matched-Pair Analysis of the TraumaRegister DGU®

A. Sirén, M. Jordan, R. Meffert, 2023, Journal of clinical medicine.

N-acetyl-leukotriene E4 is a potent constrictor of rat mesenteric vessels.

G. Feuerstein, A. Sirén, G. Letts, 1988, European Journal of Pharmacology.

Platelet-activating factor and shock.

G. Feuerstein, A. Sirén, 1988, Progress in biochemical pharmacology.

Ectopic Expression of Neurogenin 2 Alone is Sufficient to Induce Differentiation of Embryonic Stem Cells into Mature Neurons

M. Schartl, T. Wagner, E. Wischmeyer, 2012, PloS one.

Systemic and regional hemodynamic effects of leukotrienes D4 and E4 in the conscious rat.

G. Feuerstein, A. Sirén, J. Eimerl, 1986, The American journal of physiology.

Protective effect of a PAF-acether antagonist, BN 52021, in trichothecene toxicosis.

P. Braquet, G. Feuerstein, A. Sirén, 1987, Toxicology letters.

Exploiting moderate hypoxia to benefit patients with brain disease: Molecular mechanisms and translational research in progress

M. Gassmann, L. Poustka, K. Nave, 2023, Neuroprotection.

Ultrastructural analysis of wildtype and RIM1α knock-out active zones in a large cortical synapse

S. Schoch, Martin Pauli, M. Heckmann, 2022, bioRxiv.

Central cardiovascular and thermal effects of prostaglandin D2 in rats

A. Sirén, 1982 .

Combined [18F]DPA-714 micro-positron emission tomography and autoradiography imaging of microglia activation after closed head injury in mice

A. Buck, A. Sirén, S. Samnick, 2016, Journal of Neuroinflammation.

The relationship between ventricular dilatation, neuropathological and neurobehavioural changes in hydrocephalic rats

M. Shokunbi, A. Sirén, F. Olopade, 2012, Fluids and Barriers of the CNS.

Neurobehavioral and cytotoxic effects of vanadium during oligodendrocyte maturation: a protective role for erythropoietin.

A. Sirén, James Olopade, B. Oke, 2014, Environmental toxicology and pharmacology.

Tolerance and dependence following chronic intracerebroventricular infusions of Tyr-D-Arg2-Phe-Sar4 (TAPS).

A. Sirén, S. Vonhof, Bijal D Gudka, 2003, European journal of pharmacology.

Characterization of binding kinetics of [3H]Tyr-D-Arg2-Phe-Sar4 at opioid receptors.

G. Feuerstein, A. Sirén, S. Vonhof, 2003, European journal of pharmacology.

Endothelins regulate astrocyte gap junctions in rat hippocampal slices

J. Glowinski, E. Hanse, L. Venance, 2004, The European journal of neuroscience.

Hemoglobin-Independent Organ Protection by EPO in Humans: Amelioration of Cognitive Loss in Chronic Schizophrenia

J. Aldenhoff, P. Falkai, W. Maier, 2007 .

Neuroprotection in schizophrenia - What does it mean? - What means do we have?

H. Ehrenreich, A. Sirén, 2002 .

Biological activities of thionated thyrotropin-releasing hormone analogs.

L. Lankiewicz, C. Bowers, A. Sirén, 1992, Biochemical and biophysical research communications.

Active zone compaction for presynaptic strength

J. Eilers, M. Sauer, R. Kittel, 2019 .

Active zone compaction in presynaptic homeostatic potentiation

J. Eilers, M. Sauer, R. Kittel, 2020 .

Endothelin B receptor deficiency is associated with an increased rate of neuronal apoptosis in the dentate gyrus

W. Brück, H. Ehrenreich, R. Nau, 1999, Neuroscience.

Extracellular catecholamine levels in rat hippocampus after a selective alpha-2 adrenoceptor antagonist or a selective dopamine uptake inhibitor: evidence for dopamine release from local dopaminergic nerve terminals.

J. Davis, G. Feuerstein, J. Hallenbeck, 1993, The Journal of pharmacology and experimental therapeutics.

Inflammation as a risk factor for stroke: evidence from experimental models

A. Sirén, 2001 .