Ryokichi Koyama

发表

Chronic Exposure to SCO-267, an Allosteric GPR40 Full Agonist, Is Effective in Improving Glycemic Control in Rats

Ryokichi Koyama, Mitsugi Ookawara, Masanori Watanabe, 2021, Molecular Pharmacology.

Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands.

M. Naito, Ryokichi Koyama, N. Cho, 2017, Journal of medicinal chemistry.

Design, Synthesis, and Biological Evaluation of Retinoic Acid-Related Orphan Receptor γt (RORγt) Agonist Structure-Based Functionality Switching Approach from In House RORγt Inverse Agonist to RORγt Agonist.

Biching Sang, T. Imada, Terufumi Takagi, 2019, Journal of medicinal chemistry.

Rho kinase‐dependent desensitization of GPR39; a unique mechanism of GPCR downregulation

Y. Shimizu, T. Kawamoto, Ryokichi Koyama, 2017, Biochemical pharmacology.

A novel l-isoleucine hydroxylating enzyme, l-isoleucine dioxygenase from Bacillus thuringiensis, produces (2S,3R,4S)-4-hydroxyisoleucine.

S. Smirnov, J. Ogawa, Ryokichi Koyama, 2009, Biochemical and biophysical research communications.

Derivatization of inhibitor of apoptosis protein (IAP) ligands yields improved inducers of estrogen receptor α degradation

M. Naito, Ryokichi Koyama, Tomoya Sameshima, 2018, The Journal of Biological Chemistry.

In Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs)*

M. Naito, Ryokichi Koyama, Mika Teratani, 2017, The Journal of Biological Chemistry.

Glycogen synthase kinase‐3 inhibitors suppress the AR‐V7‐mediated transcription and selectively inhibit cell growth in AR‐V7‐positive prostate cancer cells

Ryokichi Koyama, T. Hara, Daisuke Nakata, 2017, The Prostate.

Cholesterol Unbound RORγt Protein Enables a Sensitive Inverse Agonist Screening.

Biching Sang, Masaharu Nakayama, Ryokichi Koyama, 2018, Assay and drug development technologies.

The enzymatic activity of inositol hexakisphosphate kinase controls circulating phosphate in mammals

Ryokichi Koyama, Masanori Watanabe, Y. Moritoh, 2021, Nature Communications.

Discovery of artificial VIPR2-antagonist peptides possessing receptor- and ligand-selectivity.

Kotaro Sakamoto, Ryokichi Koyama, Akiyoshi Tani, 2018, Biochemical and biophysical research communications.

Novel DOCK2-selective inhibitory peptide that suppresses B-cell line migration.

A. Kadotani, Kotaro Sakamoto, Ryokichi Koyama, 2017, Biochemical and biophysical research communications.