Guangbo Ge

发表

A continued saga of Boc5, the first non-peptidic glucagon-like peptide-1 receptor agonist with in vivo activities

Min He, Wei-wei Gao, Qing Liu, 2012, Acta Pharmacologica Sinica.

Identification of CYP isoforms involved in the metabolism of thymol and carvacrol in human liver microsomes (HLMs).

Guangbo Ge, Ling Yang, Z. Fang, 2012, Die Pharmazie.

Discovery and Characterization of the Naturally Occurring Inhibitors Against Human Pancreatic Lipase in Ampelopsis grossedentata

Guangbo Ge, Liangliang Zhu, Xiaodong Qin, 2022, Frontiers in Nutrition.

A Highly Selective Ratiometric Two-Photon Fluorescent Probe for Human Cytochrome P450 1A.

Tongyi Dou, Guangbo Ge, Ling Yang, 2015, Journal of the American Chemical Society.

A Mechanism-Based Model for the Prediction of the Metabolic Sites of Steroids Mediated by Cytochrome P450 3A4

Ling Yang, Guang-Bo Ge, Guangbo Ge, 2015, International journal of molecular sciences.

Stereochemical differentiation of C-7 hydroxyltaxane isomers by electrospray ionization mass spectrometry.

Zheng-Tao Wang, Li Yang, Yan-Yan Zhang, 2009, Rapid communications in mass spectrometry : RCM.

Ethnopharmacology, chemodiversity, and bioactivity of Cephalotaxus medicinal plants.

P. Xiao, Guangbo Ge, D. Hao, 2021, Chinese journal of natural medicines.

Modeling resistance index of taxoids to MCF-7 cell lines using ANN together with electrotopological state descriptors

Guangbo Ge, Ling Yang, Chunzhi Ai, 2008, Acta Pharmacologica Sinica.

Molecular Design Strategy to Construct the Near-Infrared Fluorescent Probe for Selectively Sensing Human Cytochrome P450 2J2.

T. James, Guangbo Ge, Xiaochi Ma, 2018, Journal of the American Chemical Society.

A fluorescence-based microplate assay for high-throughput screening and evaluation of human UGT inhibitors.

M. Finel, Guangbo Ge, Yin Lu, 2021, Analytica chimica acta.

A broad-spectrum substrate for the human UDP-glucuronosyltransferases and its use for investigating glucuronidation inhibitors.

M. Finel, Guangbo Ge, Chaoran Wang, 2021, International journal of biological macromolecules.

Human UDP‐Glucuronosyltransferases 1A1, 1A3, 1A9, 2B4 and 2B7 are Inhibited by Diethylstilbestrol

Y. Zhu, Y. Zhang, Guangbo Ge, 2016, Basic & clinical pharmacology & toxicology.

Assessment of the inhibition potential of Licochalcone A against human UDP-glucuronosyltransferases.

Guangbo Ge, Ling Yang, Wei Xu, 2016, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Diethylstilbestrol can effectively accelerate estradiol-17-O-glucuronidation, while potently inhibiting estradiol-3-O-glucuronidation.

Guangbo Ge, Ling Yang, Liangliang Zhu, 2015, Toxicology and applied pharmacology.

C-8 Mannich base derivatives of baicalein display improved glucuronidation stability: exploring the mechanism by experimentation and theoretical calculations

Liang Xu, Guangbo Ge, Ling Yang, 2015 .

In vitro glucuronidation of Armillarisin A: UDP-glucuronosyltransferase 1A9 acts as a major contributor and significant species differences

Guangbo Ge, Ling Yang, Liangliang Zhu, 2014, Xenobiotica; the fate of foreign compounds in biological systems.

N-Butyl-4-hydroxy-1,8-naphthalimide: A new matrix for small molecule analysis by matrix-assisted laser desorption/ionization mass spectrometry.

Huiyuan Gao, Xiaozhe Zhang, Guangbo Ge, 2017, Rapid communications in mass spectrometry : RCM.

Molecular probes for human cytochrome P450 enzymes: Recent progress and future perspectives

Guangbo Ge, Ling Yang, Xinxin Ding, 2021 .

A ratiometric fluorescent sensor for highly selective detection of human carboxylesterase 2 and its application in living cells

Guangbo Ge, Ling Yang, Jingnan Cui, 2014 .

Accurate and sensitive detection of Catechol-O-methyltransferase activity by liquid chromatography with fluorescence detection.

Guangbo Ge, Yang-Liu Xia, Yong Liu, 2020, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Discovery of hCES2A inhibitors from Glycyrrhiza inflata via combination of docking-based virtual screening and fluorescence-based inhibition assays.

Guangbo Ge, Yunqing Song, J. Hou, 2020, Food & function.

Inhibitory effects of sanguinarine on human liver cytochrome P450 enzymes.

Guangbo Ge, Ling Yang, Liangliang Zhu, 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

C-7 configuration as one of determinants in taxanes metabolism by human cytochrome P450 enzymes

J. Sun, Guangbo Ge, Y. Liu, 2009, Xenobiotica; the fate of foreign compounds in biological systems.

Inhibition of UGT1A1 by natural and synthetic flavonoids.

Ping Wang, Xia Lv, Guang-Bo Ge, 2019, International journal of biological macromolecules.

Discovery and characterization of pentacyclic triterpenoid acids in Styrax as potent and reversible pancreatic lipase inhibitors

Guangbo Ge, Shou-Ning Jia, J. Hou, 2020 .

Pentacyclic triterpenoid acids in Styrax as potent and highly specific inhibitors against human carboxylesterase 1A.

F. Zhang, Guangbo Ge, Yuan Xiong, 2020, Food & function.

An ultra-sensitive and easy-to-use assay for sensing human UGT1A1 activities in biological systems

M. Finel, Guangbo Ge, Yin Lu, 2020, Journal of pharmaceutical analysis.

Inhibition of human carboxylesterases by magnolol: Kinetic analyses and mechanism.

M. Finel, Tongyi Dou, Guangbo Ge, 2019, Chemico-biological interactions.

The Inhibitory Effect of 20(S)‐Protopanaxatriol (ppt) Towards UGT1A1 and UGT2B7

Guangbo Ge, Ling Yang, Z. Fang, 2013, Phytotherapy research : PTR.

Comparison of the inhibitory effects of tolcapone and entacapone against human UDP-glucuronosyltransferases.

Guangbo Ge, Ling Yang, Z. Fang, 2016, Toxicology and applied pharmacology.

Comparison of the inhibition potentials of icotinib and erlotinib against human UDP-glucuronosyltransferase 1A1

Guangbo Ge, Xuewei Cheng, Rui-hua Dong, 2017, Acta pharmaceutica Sinica. B.

Amentoflavone is a potent broad-spectrum inhibitor of human UDP-glucuronosyltransferases.

Guangbo Ge, Ling Yang, D. Hao, 2018, Chemico-biological interactions.

Nevadensin is a naturally occurring selective inhibitor of human carboxylesterase 1.

J. Chen, Tongyi Dou, Guangbo Ge, 2018, International journal of biological macromolecules.

Functional and Transcriptomic Characterization of a Dye-decolorizing Fungus from Taxus Rhizosphere

Z. Qin, P. Xiao, Guangbo Ge, 2018, Polish journal of microbiology.

A highly selective fluorescent ESIPT probe for the detection of Human carboxylesterase 2 and its biological applications.

Guangbo Ge, Ling Yang, Jingnan Cui, 2015, Biosensors & bioelectronics.

Deoxynojirimycin enhanced the transglycosylation activity of a glycosidase from the China white jade snail.

Guangbo Ge, Ling Yang, Hongwei Luan, 2009, Journal of biotechnology.

Pharmacokinetics and tissue distribution of five bufadienolides from the Shexiang Baoxin Pill following oral administration to mice.

Weidong Zhang, Lin Han, C. Lv, 2015, Journal of ethnopharmacology.

Tissue and species differences in the glucuronidation of glabridin with UDP-glucuronosyltransferases.

F. Gonzalez, Guangbo Ge, Ling Yang, 2015, Chemico-biological interactions.

Glucuronidation of bavachinin by human tissues and expressed UGT enzymes: Identification of UGT1A1 and UGT1A8 as the major contributing enzymes.

Z. Xiu, Guangbo Ge, Ling Yang, 2015, Drug metabolism and pharmacokinetics.

Synthesis and Structure‐Activity Relationships of 3‐Arylisoquinolone Analogues as Highly Specific hCES2A Inhibitors

Weiliang Zhu, Kaixian Chen, Yong Zhang, 2020, ChemMedChem.

Discovery of natural alkaloids as potent and selective inhibitors against human carboxylesterase 2.

Guangbo Ge, Yunqing Song, Meng-Ru Sun, 2020, Bioorganic chemistry.

Discovery of natural pentacyclic triterpenoids as potent and selective inhibitors against human carboxylesterase 1.

Guangbo Ge, Ling Yang, Ya-di Zhu, 2019, Fitoterapia.

Recent progress in the discovery of natural inhibitors against human carboxylesterases.

Guangbo Ge, Ling Yang, J. Hou, 2017, Fitoterapia.

Metabolic Profiling and Cytochrome P450 Reaction Phenotyping of Medroxyprogesterone Acetate

Yan-Yan Zhang, Guangbo Ge, Ling Yang, 2008, Drug Metabolism and Disposition.

High-throughput optical assays for sensing serine hydrolases in living systems and their applications

J. Zhang, Guangbo Ge, Yunqing Song, 2022, TrAC Trends in Analytical Chemistry.

Pancreatic Lipase Inhibitory Cyclohexapeptides from the Marine Sponge-Derived Fungus Aspergillus sp. 151304.

Guangbo Ge, Hua Han, Hou‐Wen Lin, 2020, Journal of natural products.

Chemotaxonomic study of medicinal Taxus species with fingerprint and multivariate analysis.

Zheng-Tao Wang, Yan-Yan Zhang, Guangbo Ge, 2008, Planta medica.

Discovery of human pancreatic lipase inhibitors from root of Rhodiola crenulata via integrating bioactivity-guided fractionation, chemical profiling and biochemical assay

Guangbo Ge, Xiaodong Qin, Xu-Dong Hou, 2022, Journal of pharmaceutical analysis.

Profiling of yew hair roots from various species using ultra-performance liquid chromatography/electrospray ionization mass spectrometry.

Zheng-Tao Wang, Li Yang, Yan-Yan Zhang, 2008, Rapid communications in mass spectrometry : RCM.

New insights for the risk of bisphenol A: inhibition of UDP-glucuronosyltransferases (UGTs).

Yan-Yan Zhang, Guangbo Ge, Ling Yang, 2013, Chemosphere.

Sensing and imaging of exosomal CD26 secreted from cancer cells and 3D colorectal tumor model using a novel near-infrared fluorogenic probe.

Hong-xin Li, Guangbo Ge, Ling Yang, 2021, Materials science & engineering. C, Materials for biological applications.

Reversible inhibition of four important human liver cytochrome P450 enzymes by diethylstilbestrol.

Guangbo Ge, Z. Fang, Li-ming Wang, 2011, Die Pharmazie.

CYP3A catalyses schizandrin biotransformation in human, minipig and rat liver microsomes

J. Li, Guangbo Ge, Z. Fang, 2010, Xenobiotica; the fate of foreign compounds in biological systems.

Characterization of human cytochrome P450 isoforms involved in the metabolism of 7-epi-paclitaxel

J. Sun, Guangbo Ge, Y. Liu, 2009, Xenobiotica; the fate of foreign compounds in biological systems.

Characterization of triptolide hydroxylation by cytochrome P450 in human and rat liver microsomes

J. Sun, Guangbo Ge, Y. Liu, 2008, Xenobiotica; the fate of foreign compounds in biological systems.

Target Enzyme-Activated Two-Photon Fluorescent Probes: A Case Study of CYP3A4 Using a Two-Dimensional Design Strategy.

T. James, Guangbo Ge, Xiaochi Ma, 2019, Angewandte Chemie.

Quantitative analysis of cytochrome P450 isoforms in human liver microsomes by the combination of proteomics and chemical probe‐based assay

Guangbo Ge, Ling Yang, Lianghai Hu, 2014, Proteomics.

Study of a series of fluorophore-labeled artesunate derivatives – Design, analysis and application

Su-shing Chen, Shiguo Sun, Guangbo Ge, 2017 .

Inhibition of drug-metabolizing enzymes by Qingfei Paidu decoction: Implication of herb-drug interactions in COVID-19 pharmacotherapy

Hong-Zhuan Chen, Guangbo Ge, Ling Yang, 2021, Food and Chemical Toxicology.

Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu

F. Zhang, Guangbo Ge, Ling Yang, 2019, Front. Pharmacol..

Characterization and structure-activity relationship studies of flavonoids as inhibitors against human carboxylesterase 2.

Tongyi Dou, Guangbo Ge, Wei-dong Zhang, 2018, Bioorganic chemistry.

Inhibition of human cytochrome P450 enzymes by licochalcone A, a naturally occurring constituent of licorice.

Guangbo Ge, Wei Xu, J. Ning, 2015, Toxicology in vitro : an international journal published in association with BIBRA.

Purification and characterization of a novel glycosidase from the China white jade snail (Achatina fulica) showing transglycosylation activity

Guangbo Ge, Ling Yang, Hongwei Luan, 2008 .

A model of in vitro UDP-glucuronosyltransferase inhibition by bile acids predicts possible metabolic disorders[S]

F. Gonzalez, R. He, Guangbo Ge, 2013, Journal of Lipid Research.

Induction of CYP1A1 increases gefitinib-induced oxidative stress and apoptosis in A549 cells.

Yong Liu, Guangbo Ge, Ling Yang, 2017, Toxicology in vitro : an international journal published in association with BIBRA.

A highly selective probe for human cytochrome P450 3A4: isoform selectivity, kinetic characterization and its applications.

Guangbo Ge, Ling Yang, Xiaochi Ma, 2013, Chemical communications.

Biotransformation of Glycoginsenosides to Intermediate Products and Aglycones using a Hemicellulosome Produced by Cellulosimicrobium cellulan

Tongyi Dou, Guangbo Ge, Xing-Kai Qian, 2019, Applied Biochemistry and Microbiology.

Quantitative structure-retention relationship studies for taxanes including epimers and isomeric metabolites in ultra fast liquid chromatography.

Yan-Yan Zhang, Guangbo Ge, Ling Yang, 2009, Journal of chromatography. A.

Discovery and characterization of naturally occurring chalcones as potent inhibitors of bile salt hydrolases

Chun Xing Li, Guangbo Ge, J. Hou, 2022, Acta Materia Medica.

Discovery and characterization of naturally occurring potent inhibitors of catechol-O-methyltransferase from herbal medicines

F. Gonzalez, Guangbo Ge, Ling Yang, 2021, RSC advances.

Human carboxylesterase 1A plays a predominant role in the hydrolytic activation of remdesivir in humans.

Feng Zhang, Hong-xin Li, Guangbo Ge, 2021, Chemico-biological interactions.

Inhibition of drug-metabolizing enzymes by Jingyin granules: implications of herb–drug interactions in antiviral therapy

Hong-Zhuan Chen, Guangbo Ge, Qi-long Chen, 2021, Acta Pharmacologica Sinica.

Carboxylesterase inhibitors from clinically available medicines and their impact on drug metabolism.

Guangbo Ge, Yunqing Song, J. Hou, 2021, Chemico-biological interactions.

A highly selective near-infrared fluorescent probe for carboxylesterase 2 and its bioimaging applications in living cells and animals.

Guangbo Ge, Ling Yang, Z. Dai, 2016, Biosensors & bioelectronics.

A highly selective fluorescent probe for sensing activities of catechol-O-methyltransferase in complex biological samples

Tongyi Dou, Guangbo Ge, Ling Yang, 2016 .

Bysspectin A, an unusual octaketide dimer and the precursor derivatives from the endophytic fungus Byssochlamys spectabilis IMM0002 and their biological activities.

Sheng Lin, Guangbo Ge, Huawei Zhang, 2018, European journal of medicinal chemistry.

Theophylline Acetaldehyde as the Initial Product in Doxophylline Metabolism in Human Liver

Shuyue Xia, Guangbo Ge, Ling Yang, 2020, Drug Metabolism and Disposition.

Interspecies comparison in the COMT-mediated methylation of 3-BTD

Tongyi Dou, Guangbo Ge, Yang-Liu Xia, 2018, RSC advances.

Accurate and sensitive detection of dipeptidyl peptidase-IV activity by liquid chromatography with fluorescence detection

Guangbo Ge, Jing Zhang, Q. Jin, 2020 .

Arenobufagin is a novel isoform-specific probe for sensing human sulfotransferase 2A1

G. Wang, Guangbo Ge, Xiaochi Ma, 2018, Acta pharmaceutica Sinica. B.

Characterization of regio- and stereo-selective sulfation of bufadienolides: exploring the mechanism and providing insight into the structure–sulfation relationship by experimentation and molecular docking analysis

T. Ma, Xiaochi Ma, Guangbo Ge, 2016 .

Interspecies variation in phase I metabolism of bufalin in hepatic microsomes from mouse, rat, dog, minipig, monkey, and human

Guangbo Ge, Ling Yang, Xiaochi Ma, 2015, Xenobiotica; the fate of foreign compounds in biological systems.

Characterization of Phase I Metabolism of Resibufogenin and Evaluation of the Metabolic Effects on Its Antitumor Activity and Toxicity

Guangbo Ge, Ling Yang, Xiaochi Ma, 2015, Drug Metabolism and Disposition.

Comprehensive profiling and characterization of the absorbed components and metabolites in mice serum and tissues following oral administration of Qing-Fei-Pai-Du decoction by UHPLC-Q-Exactive-Orbitrap HRMS.

Guangbo Ge, Ling Yang, Ping Liu, 2020, Chinese journal of natural medicines.

Drug metabolism and pharmacokinetic diversity of ranunculaceae medicinal compounds.

P. Xiao, Guangbo Ge, Ling Yang, 2015, Current drug metabolism.

Inhibition of human catechol-O-methyltransferase-mediated dopamine O-methylation by daphnetin and its Phase II metabolites

Guangbo Ge, Yang Ling, S. Liang, 2017, Xenobiotica; the fate of foreign compounds in biological systems.

Design, synthesis and biological evaluation of novel chalcone-like compounds as potent and reversible pancreatic lipase inhibitors.

Nan Zhang, P. Liu, Guangbo Ge, 2020, Bioorganic & medicinal chemistry.

Succinate Mediates Tumorigenic Effects via Succinate Receptor 1: Potential for New Targeted Treatment Strategies in Succinate Dehydrogenase Deficient Paragangliomas

M. Merino, H. Lehnert, M. Schwaninger, 2021, Frontiers in Endocrinology.

Interspecies variation of clopidogrel hydrolysis in liver microsomes from various manmmals.

Guangbo Ge, D. Hao, Yunqing Song, 2020, Chemico-biological interactions.

A highly sensitive and selective two-photon fluorescent probe for real-time sensing of cytochrome P450 1A1 in living systems

Guangbo Ge, Xiaochi Ma, Xiangge Tian, 2018 .

Structure-inhibition relationship of ginsenosides towards UDP-glucuronosyltransferases (UGTs).

Yan-Yan Zhang, Guangbo Ge, Ling Yang, 2013, Toxicology and applied pharmacology.

Natural constituents from Cortex Mori Radicis as new pancreatic lipase inhibitors.

Guangbo Ge, Yun-feng Cao, Z. Dai, 2018, Bioorganic chemistry.

Design, synthesis and biological evaluation of esculetin derivatives as anti-tumour agents

Guangbo Ge, Ling Yang, Lei Feng, 2015 .

Sensing cytochrome P450 1A1 activity by a resorufin-based isoform-specific fluorescent probe

Guangbo Ge, Ling Yang, Lei Feng, 2020 .

Characterization of UDP-glucuronosyltransferases involved in glucuronidation of diethylstilbestrol in human liver and intestine.

Guangbo Ge, Ling Yang, Liangliang Zhu, 2012, Chemical research in toxicology.

A lysosomal probe for monitoring of pH in living cells and ovarian tumour

Shiguo Sun, Xiaojun Peng, Guangbo Ge, 2017 .

Discovery and characterization of flavonoids in vine tea as catechol-O-methyltransferase inhibitors.

Guangbo Ge, Ling Yang, Hao Yu, 2021, Fitoterapia.

Design, synthesis and biological evaluation of indanone-chalcone hybrids as potent and selective hCES2A inhibitors.

N. Zhang, P. Liu, Guangbo Ge, 2020, European journal of medicinal chemistry.

Herb-drug interaction between Styrax and warfarin: Molecular basis and mechanism.

Guangbo Ge, Yan Xiang, Peng-Chao Huo, 2020, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Transcriptome Profile of Polycyclic Aromatic Hydrocarbon-Degrading Fungi Isolated from Taxus rhizosphere

Guangbo Ge, D. Hao, S. Song, 2019, Current Science.

Interactions of drug-metabolizing enzymes with the Chinese herb Psoraleae Fructus.

Guangbo Ge, Liangliang Zhu, Yunqing Song, 2019, Chinese journal of natural medicines.

Carboxylesterase Inhibitors: Relevance for Pharmaceutical Applications

Guangbo Ge, Li-Wei Zou, 2019, Pharmaceutical Biocatalysis.

Acceptor Specificity and Transfer Efficiency of a β-Glycosidase from the China White Jade Snail

Guangbo Ge, Ling Yang, Hongwei Luan, 2009 .

Inhibition of human carboxylesterases by ginsenosides: structure–activity relationships and inhibitory mechanism

Tongyi Dou, Guangbo Ge, Ling Yang, 2019, Chinese Medicine.

Comparative metabolism of DDAO benzoate in liver microsomes from various species.

Guangbo Ge, Ling Yang, D. Hao, 2017, Toxicology in vitro : an international journal published in association with BIBRA.

Assessment of the inhibitory effects of pyrethroids against human carboxylesterases

Tongyi Dou, H. Yin, Guangbo Ge, 2017, Toxicology and applied pharmacology.

A highly selective marker reaction for measuring the activity of human carboxylesterase 1 in complex biological samples

Guangbo Ge, Ling Yang, D. Hao, 2016 .

A highly selective ratiometric fluorescent probe for in vitro monitoring and cellular imaging of human carboxylesterase 1.

Guangbo Ge, Ling Yang, Yun-feng Cao, 2014, Biosensors & bioelectronics.

In vitro phase I metabolism of gamabufotalin and arenobufagin: Reveal the effect of substituent group on metabolic stability.

Guangbo Ge, Ling Yang, Xiaochi Ma, 2017, Fitoterapia.

A mitochondrial targeting fluorescent probe based on the covalently linked anti-inflammatory drug dexamethasone and Cy7

Su-shing Chen, Shiguo Sun, Xiaojun Peng, 2017 .

Reversible and Irreversible Inhibition of Cytochrome P450 Enzymes by Methylophiopogonanone A

Guangbo Ge, Jing-Jing Wu, Dongzhu Tu, 2020, Drug Metabolism and Disposition.

Three new polyoxygenated bergamotanes from the endophytic fungus Penicillium purpurogenum IMM 003 and their inhibitory activity against pancreatic lipase.

Sheng Lin, Guangbo Ge, P. Lin, 2020, Chinese journal of natural medicines.

Structural Modifications at the C-4 Position Strongly Affect the Glucuronidation of 6,7-Dihydroxycoumarins

Guangbo Ge, Ling Yang, J. Ning, 2015, Drug Metabolism and Disposition.

Microsoft Word-80428080-file00

Guangbo Ge, Ling Yang, J. Ning, 2015 .

Enantioselective [3+2] annulation of isatin-derived MBH-carbonates and 3-nitroindoles enabled by a bifunctional DMAP-thiourea.

Guangbo Ge, Dingding Gao, G. Lin, 2020, Chemical communications.

Synthesis and biological evaluation of hydroxylcoumarin derivatives as antioxidant agents

C. Chen, Guangbo Ge, Ling Yang, 2017, Chemical Research in Chinese Universities.

Asymmetric Construction of a Multi-Pharmacophore-Containing Dispirotriheterocyclic Scaffold and Identification of a Human Carboxylesterase 1 Inhibitor.

Shiqiang Wei, Guangbo Ge, Baomin Wang, 2018, Organic letters.

A bioluminescent sensor reveals that carboxylesterase 1A is a novel endoplasmic reticulum-derived serologic indicator for hepatocyte injury.

Guangbo Ge, Ling Yang, Q. Jin, 2020, ACS sensors.

Human carboxylesterases: a comprehensive review

Guangbo Ge, Ling Yang, J. Hou, 2018, Acta pharmaceutica Sinica. B.

Carboxylesterase Inhibitors: An Update.

Guangbo Ge, Ling Yang, D. Hao, 2017, Current medicinal chemistry.

Synthesis and structure-activity relationship of coumarins as potent Mcl-1 inhibitors for cancer treatment.

F. Gonzalez, Guangbo Ge, Yang-Liu Xia, 2020, Bioorganic & medicinal chemistry.

Synthesis and Structure-Activity Relationship of Daphnetin Derivatives as Potent Antioxidant Agents

Tongyi Dou, Guangbo Ge, Yong Liu, 2018, Molecules.

An Optimized Two-Photon Fluorescent Probe for Biological Sensing and Imaging of Catechol-O-Methyltransferase.

Yang Yu, Ling Yang, Guang-Bo Ge, 2017, Chemistry.

Identification and Characterization of Human UDP-Glucuronosyltransferases Responsible for the In Vitro Glucuronidation of Daphnetin

Yan-Yan Zhang, Guangbo Ge, Ling Yang, 2010, Drug Metabolism and Disposition.

Identification of Vitamin K3 and its analogues as covalent inhibitors of SARS-CoV-2 3CLpro

Chun Xing Li, Hongzhuan Chen, Guangbo Ge, 2021, International Journal of Biological Macromolecules.

Discovery and Characterization of the Biflavones From Ginkgo biloba as Highly Specific and Potent Inhibitors Against Human Carboxylesterase 2

Guangbo Ge, Yunqing Song, J. Hou, 2021, Frontiers in Pharmacology.

Biflavones from Ginkgo biloba as inhibitors of human thrombin.

Fangjun Wang, Guangbo Ge, Wenzhi Guo, 2019, Bioorganic chemistry.

A highly selective long-wavelength fluorescent probe for the detection of human carboxylesterase 2 and its biomedical applications.

Liang Xu, Guangbo Ge, Ling Yang, 2014, Chemical communications.

The comparison analysis of polyphyllin I and its analogues induced apoptosis of colon and lung cancer cells via mitochondrial dysfunction

Guangbo Ge, Ming Lei, Ya-di Zhu, 2021, Basic & clinical pharmacology & toxicology.

Metabolism and pharmacokinetics of alantolactone and isoalantolactone in rats: Thiol conjugation as a potential metabolic pathway.

Weidong Zhang, Shumei Wang, Guangbo Ge, 2018, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Flavipesides A-C, PKS-NRPS Hybrids as Pancreatic Lipase Inhibitors from a Marine Sponge Symbiotic Fungus Aspergillus flavipes 164013.

Guangbo Ge, Hou‐Wen Lin, Wei-Hua Jiao, 2020, Organic letters.

Biflavones from Ginkgo biloba as novel pancreatic lipase inhibitors: Inhibition potentials and mechanism.

Guangbo Ge, Huiliang Li, Z. Dai, 2018, International journal of biological macromolecules.

Purpurolide A, 5/5/5 Spirocyclic Sesquiterpene Lactone in Nature from the Endophytic Fungus Penicillium purpurogenum.

Sheng Lin, Guangbo Ge, Huawei Zhang, 2018, Organic letters.

Anticancer Drug Targets of Salvia Phytometabolites: Chemistry, Biology and Omics.

P. Xiao, Guangbo Ge, D. Hao, 2018, Current drug targets.

Identification of UDP-glucuronosyltransferase isoforms involved in hepatic and intestinal glucuronidation of phytochemical carvacrol

Guangbo Ge, Ling Yang, Z. Fang, 2012, Xenobiotica; the fate of foreign compounds in biological systems.

Paeonone A, a novel nonanortriterpenoid from the roots of Paeonia lactiflora.

Sheng Lin, Guangbo Ge, Yunqing Song, 2021, Bioorganic chemistry.

Deoxyschizandrin, a Naturally Occurring Lignan, Is a Specific Probe Substrate of Human Cytochrome P450 3A

Guangbo Ge, Ling Yang, Liangliang Zhu, 2014, Drug Metabolism and Disposition.

Systems pharmacological study illustrates the immune regulation, anti-infection, anti-inflammation, and multi-organ protection mechanism of Qing-Fei-Pai-Du decoction in the treatment of COVID-19

Weidong Zhang, Jian Yang, S. Tian, 2020, Phytomedicine.

Identification and characterization of human UDP-glucuronosyltransferases responsible for xanthotoxol glucuronidation

M. Finel, Guangbo Ge, Ling Yang, 2018, Xenobiotica; the fate of foreign compounds in biological systems.

Identification and characterization of naturally occurring inhibitors against human carboxylesterase 2 in White Mulberry Root-bark.

Guangbo Ge, Ling Yang, Yanfang Liu, 2016, Fitoterapia.

Inhibition behavior of fructus psoraleae’s ingredients towards human carboxylesterase 1 (hCES1)

Guangbo Ge, Z. Fang, H. Hua, 2016, Xenobiotica; the fate of foreign compounds in biological systems.

Fructus Psoraleae contains natural compounds with potent inhibitory effects towards human carboxylesterase 2.

Guangbo Ge, Ling Yang, X. Lv, 2015, Fitoterapia.

Pancreatic lipase inhibitory constituents from Fructus Psoraleae.

Guangbo Ge, Qi Zhou, Yun-feng Cao, 2020, Chinese journal of natural medicines.

Protostane Triterpenoids from the Rhizome of Alisma orientale Exhibit Inhibitory Effects on Human Carboxylesterase 2.

Guangbo Ge, Xiaochi Ma, Xiaokui Huo, 2015, Journal of natural products.

Species-associated differences in the inhibition of propofol glucuronidation by magnolol.

Guangbo Ge, Ling Yang, Liangliang Zhu, 2014, Journal of the American Association for Laboratory Animal Science : JAALAS.

Potent and selective inhibition of magnolol on catalytic activities of UGT1A7 and 1A9

Guangbo Ge, Ling Yang, G. He, 2012, Xenobiotica; the fate of foreign compounds in biological systems.

Characterization of Hepatic and Intestinal Glucuronidation of Magnolol: Application of the Relative Activity Factor Approach to Decipher the Contributions of Multiple UDP-Glucuronosyltransferase Isoforms

M. Finel, Guangbo Ge, Ling Yang, 2012, Drug Metabolism and Disposition.

Characterization of hepatic and intestinal glucuronidation of magnolol: application of the RAF approach to decipher the contributions of multiple UGT isoforms

M. Finel, Guangbo Ge, Ling Yang, 2011 .

Comparative Metabolism of Cinobufagin in Liver Microsomes from Mouse, Rat, Dog, Minipig, Monkey, and Human

Guangbo Ge, Ling Yang, Xiaochi Ma, 2011, Drug Metabolism and Disposition.

Spectrophotometric Assays for Sensing Tyrosinase Activity and Their Applications

Guangbo Ge, Dong-Fang Zhao, Yan Xiang, 2021, Biosensors.

Recent progress and challenges in screening and characterization of UGT1A1 inhibitors

M. Finel, Guangbo Ge, Ling Yang, 2018, Acta pharmaceutica Sinica. B.

Analytical methodologies for sensing catechol-O-methyltransferase activity and their applications

F. Gonzalez, Guangbo Ge, Ling Yang, 2020, Journal of pharmaceutical analysis.

Correction to ''Molecular Design Strategy to Construct the Near-Infrared Fluorescent Probe for Selectively Sensing Human Cytochrome P450 2J2''.

T. James, Guangbo Ge, Xiaochi Ma, 2019, Journal of the American Chemical Society.

Identification and characterization of human UDP‐glucuronosyltransferases responsible for the in‐vitro glucuronidation of arctigenin

W. Xu, Guangbo Ge, Ling Yang, 2015, The Journal of pharmacy and pharmacology.

Rapalogues as hCES2A Inhibitors: In Vitro and In Silico Investigations

Guangbo Ge, Yunqing Song, Meng-Ru Sun, 2020, European Journal of Drug Metabolism and Pharmacokinetics.

Rapalogues as hCES2A Inhibitors: In Vitro and In Silico Investigations

Li-Rong Zhang, Guangbo Ge, Yunqing Song, 2020, European Journal of Drug Metabolism and Pharmacokinetics.

Evidence for Shikonin acting as an active inhibitor of human carboxylesterases 2: Implications for herb–drug combination

R. He, Guangbo Ge, Yun-feng Cao, 2018, Phytotherapy research : PTR.

Design, synthesis, and structure-activity relationship study of glycyrrhetinic acid derivatives as potent and selective inhibitors against human carboxylesterase 2.

Guangbo Ge, Ling Yang, D. Hao, 2016, European journal of medicinal chemistry.

A Two-Photon Ratiometric Fluorescent Probe for Imaging Carboxylesterase 2 in Living Cells and Tissues.

Guangbo Ge, Ling Yang, Zhi-Hong Liu, 2015, ACS applied materials & interfaces.

Bioactivity-Guided Discovery of Human Carboxylesterase Inhibitors from the Roots of Paeonia lactiflora.

Sheng Lin, Guangbo Ge, Yunqing Song, 2020, Journal of natural products.

Investigation of UDP‐glucuronosyltransferases (UGTs) Inhibitory Properties of Carvacrol

Guangbo Ge, Ling Yang, Z. Fang, 2012, Phytotherapy research : PTR.

Comparative Metabolism of Cinobufagin in Liver Microsomes from Mouse, Rat, Dog, Minipig, Monkey and Human

Guangbo Ge, Ling Yang, Xiaochi Ma, 2011 .

Methylation, Glucuronidation, and Sulfonation of Daphnetin in Human Hepatic Preparations In Vitro: Metabolic Profiling, Pathway Comparison, and Bioactivity Analysis.

Guangbo Ge, Ling Yang, S. Liang, 2016, Journal of pharmaceutical sciences.

Oxidative Coupling of â‐O‐4′ Dilignol Models Leading to Polycyclic Products with Rare Interlignol Linkages

Z. Zhao, Guangbo Ge, Chang Peng, 2017 .

Structure-Activity Relationships of Pentacyclic Triterpenoids as Potent and Selective Inhibitors against Human Carboxylesterase 1

Tongyi Dou, Guangbo Ge, Ling Yang, 2017, Front. Pharmacol..

Chemical Probes for Human UDP‐Glucuronosyltransferases: A Comprehensive Review

Tongyi Dou, Guangbo Ge, Ling Yang, 2018, Biotechnology journal.

Regioselective Glucuronidation of Andrographolide and Its Major Derivatives: Metabolite Identification, Isozyme Contribution, and Species Differences

Guangbo Ge, Xiaochi Ma, Xiangge Tian, 2015, The AAPS Journal.

Erratum to: Regioselective Glucuronidation of Andrographolide and Its Major Derivatives: Metabolite Identification, Isozyme Contribution, and Species Differences

Guangbo Ge, Ling Yang, Xiaochi Ma, 2014, The AAPS Journal.

Tet2 regulates Barx2 expression in undifferentiated and early differentiated mouse embryonic stem cells.

F. Lan, Changwei Li, Guangbo Ge, 2020, Biochemical and biophysical research communications.

A novel approach for fluorescent visualization of glycyrrhetic acid on a cell with a quantum dot

Guangbo Ge, G. Bai, Qian Shi, 2014, Biochemistry (Moscow).

Taxane's Substituents at C3′ Affect Its Regioselective Metabolism: Different in Vitro Metabolism of Cephalomannine and Paclitaxel

Zheng-Tao Wang, Yan-Yan Zhang, Guangbo Ge, 2008, Drug Metabolism and Disposition.

Deciphering the species differences in CES1A-mediated hydrolytic metabolism by using a bioluminescence substrate.

Guangbo Ge, Q. Jin, Dan-Dan Wang, 2022, Chemico-biological interactions.

Inhibition of pancreatic lipase by environmental xenoestrogens.

H. Yin, Guangbo Ge, Ling Yang, 2020, Ecotoxicology and environmental safety.

Rational Design of a Long-Wavelength Fluorescent Probe for Highly Selective Sensing of Carboxylesterase 1 in Living Systems.

Tongyi Dou, Kun Li, Guangbo Ge, 2019, Analytical chemistry.

A bioluminescent sensor for highly selective and sensitive detection of human carboxylesterase 1 in complex biological samples.

Guangbo Ge, Ling Yang, X. Lv, 2016, Chemical communications.

Identification and characterization of naturally occurring inhibitors against UDP-glucuronosyltransferase 1A1 in Fructus Psoraleae (Bu-gu-zhi).

Guangbo Ge, Ling Yang, Yun-feng Cao, 2015, Toxicology and applied pharmacology.

The First Insight into the Tissue Specific Taxus Transcriptome via Illumina Second Generation Sequencing

Peigen Xiao, Guangbo Ge, Ling Yang, 2011, PloS one.

Cycloartane triterpenoids from Cimicifuga yunnanensis induce apoptosis of breast cancer cells (MCF7) via p53‐dependent mitochondrial signaling pathway

Guangbo Ge, Ling Yang, Z. Fang, 2011, Phytotherapy research : PTR.

Transgelin-2 as a therapeutic target for asthmatic pulmonary resistance

Shuang Huang, Zhijian Xu, Linhong Deng, 2018, Science Translational Medicine.

New Insights into SN‐38 Glucuronidation: Evidence for the Important Role of UDP Glucuronosyltransferase 1A9

Guangbo Ge, Liangliang Zhu, Yun-feng Cao, 2018, Basic & clinical pharmacology & toxicology.

UGT1A10 Is a High Activity and Important Extrahepatic Enzyme: Why Has Its Role in Intestinal Glucuronidation Been Frequently Underestimated?

M. Finel, Guangbo Ge, Ling Yang, 2017, Molecular pharmaceutics.

[The relationship between catechol O-methyltransferase and diseases].

Tongyi Dou, Guangbo Ge, Ling Yang, 2016, Yao xue xue bao = Acta pharmaceutica Sinica.

Discovery and Characterization of the Key Constituents in Ginkgo biloba Leaf Extract With Potent Inhibitory Effects on Human UDP-Glucuronosyltransferase 1A1

Tongyi Dou, Guangbo Ge, Guanghao Zhu, 2022, Frontiers in Pharmacology.

Structure-activity relationships of flavonoids as natural inhibitors against E. coli β-glucuronidase.

Tongyi Dou, Guangbo Ge, Ling Yang, 2017, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Time-dependent inhibition (TDI) of CYP3A4 and CYP2C9 by noscapine potentially explains clinical noscapine-warfarin interaction.

Yan-Yan Zhang, Guangbo Ge, Ling Yang, 2010, British journal of clinical pharmacology.

Discovery of a highly specific and efficacious inhibitor of human carboxylesterase 2 by large-scale screening.

Guangbo Ge, Yun-feng Cao, J. Chen, 2019, International journal of biological macromolecules.

Sensing carboxylesterase 1 in living systems by a practical and isoform-specific fluorescent probe

Tongyi Dou, Guangbo Ge, Jingnan Cui, 2019, Chinese Chemical Letters.

The role of serum albumin in the metabolism of Boc5: molecular identification, species differences and contribution to plasma metabolism.

Guangbo Ge, Ling Yang, Z. Fang, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Glucuronidation of the broad‐spectrum antiviral drug arbidol by UGT isoforms

Guangbo Ge, Z. Fang, Liangliang Zhu, 2013, The Journal of pharmacy and pharmacology.

Discovery of naturally occurring inhibitors against SARS-CoV-2 3CLpro from Ginkgo biloba leaves via large-scale screening

Hong-Zhuan Chen, Guangbo Ge, Huiliang Li, 2021, Fitoterapia.

Discovery of 9,10-dihydrophenanthrene derivatives as SARS-CoV-2 3CLpro inhibitors for treating COVID-19

Xiaodi Yang, Guangbo Ge, Dingding Gao, 2021, European Journal of Medicinal Chemistry.

Deciphering the metabolic fates of herbal constituents and the interactions of herbs with human metabolic system.

Guangbo Ge, 2019, Chinese journal of natural medicines.

A highly specific ratiometric two-photon fluorescent probe to detect dipeptidyl peptidase IV in plasma and living systems

Guangbo Ge, Ling Yang, Zhi-Hong Liu, 2016, Biosensors and Bioelectronics.

CPF impedes cell cycle re‐entry of quiescent lung cancer cells through transcriptional suppression of FACT and c‐MYC

Xiaodong Zhao, P. de Souza, Guangbo Ge, 2020, Journal of cellular and molecular medicine.

An ultrasensitive and conformation sensitive fluorescent probe for sensing human albumin in complex biological samples

Liang Xu, Guangbo Ge, Jingnan Cui, 2017 .

A rapid-response fluorescent probe for the sensitive and selective detection of human albumin in plasma and cell culture supernatants.

Guangbo Ge, Ling Yang, Jingnan Cui, 2016, Chemical communications.

Natural constituents of St. John's Wort inhibit the proteolytic activity of human thrombin.

Tongyi Dou, Guangbo Ge, Yun-feng Cao, 2019, International journal of biological macromolecules.

Biological, Chemical, and Omics Research of Taxus Medicinal Resources

Guang-Bo Ge, Pei-Gen Xiao, Da-Cheng Hao, 2012 .

Neobavaisoflavone Induces Bilirubin Metabolizing Enzyme UGT1A1 via PPARα and PPARγ

M. Finel, Guangbo Ge, Ming Lei, 2021, Frontiers in Pharmacology.

Rapid bioluminescence assay for monitoring rat CES1 activity and its alteration by traditional Chinese medicines

Z. Zuo, Guangbo Ge, Ling Yang, 2020, Journal of pharmaceutical analysis.

Bacterial diversity of Taxus rhizosphere: culture-independent and culture-dependent approaches.

Ling Yang, Guangbo Ge, Ling Yang, 2008, FEMS microbiology letters.

Active post-transcriptional regulation and ACLY-mediated acetyl-CoA synthesis as a pivotal target of Shuang-Huang-Sheng-Bai formula for lung adenocarcinoma treatment.

Wei Liu, Guangbo Ge, Zhongqi Wang, 2023, Phytomedicine : international journal of phytotherapy and phytopharmacology.

A Novel Analgesic Isolated from a Traditional Chinese Medicine

E. Borrelli, G. Parks, Xinmiao Liang, 2014, Current Biology.

In vitro evaluation of the effect of C-4 substitution on methylation of 7,8-dihydroxycoumarin: metabolic profile and catalytic kinetics

Tongyi Dou, Guangbo Ge, Ling Yang, 2018, Royal Society Open Science.

In Vitro Evaluation of the Effect of 7-Methyl Substitution on Glucuronidation of Daphnetin: Metabolic Stability, Isoform Selectivity, and Bioactivity Analysis.

Guangbo Ge, Ling Yang, S. Liang, 2015, Journal of pharmaceutical sciences.

Sophoridine Inhibits the Tumour Growth of Non-Small Lung Cancer by Inducing Macrophages M1 Polarisation via MAPK-Mediated Inflammatory Pathway

Guangbo Ge, Jian Huang, Hairong Zeng, 2021, Frontiers in Oncology.

Real-Time Tracking the Synthesis and Degradation of Albumin in Complex Biological Systems with a near-Infrared Fluorescent Probe.

Fang Wang, Guangbo Ge, Ling Yang, 2017, Analytical chemistry.

A Naturally Occurring Isoform-Specific Probe for Highly Selective and Sensitive Detection of Human Cytochrome P450 3A5.

Tongyi Dou, Guangbo Ge, Ling Yang, 2017, Journal of medicinal chemistry.

Gomisin A is a Novel Isoform-Specific Probe for the Selective Sensing of Human Cytochrome P450 3A4 in Liver Microsomes and Living Cells

Guangbo Ge, Ling Yang, Z. Dai, 2015, The AAPS Journal.

Inhibition of pancreatic lipase by the constituents in St. John's Wort: In vitro and in silico investigations.

Guangbo Ge, Ling Yang, Qi Zhou, 2019, International journal of biological macromolecules.

Investigation of binding features: Effects on the interaction between CYP2A6 and inhibitors

Wei Li, Ling Yang, Yan Li, 2010, J. Comput. Chem..

Interspecies Variation in NCMN-O-Demethylation in Liver Microsomes from Various Species

Guangbo Ge, Ling Yang, Guibo Sun, 2019, Molecules.

Pharmacokinetic interaction between a Chinese herbal formula Huosu Yangwei oral liquid and apatinib in vitro and in vivo

Guangbo Ge, Liangliang Zhu, Sheng-Quan Fang, 2020, The Journal of pharmacy and pharmacology.

Transcriptional profiling and network pharmacology analysis identify the potential biomarkers from Chinese herbal formula Huosu Yangwei Formula treated gastric cancer in vivo

Guangbo Ge, Kun Zhao, Sheng-Quan Fang, 2021, Chinese Journal of Natural Medicines.

Inhibition of drug-metabolizing enzymes by Jingyin granules: implications of herb–drug interactions in antiviral therapy

Hong-Zhuan Chen, Guangbo Ge, Wei-Dong Zhang, 2021, Acta pharmacologica Sinica.

Microsoft Word-87842789-file00

Guangbo Ge, Ling Yang, Z. Fang, 2010 .

A Practical and High-Affinity Fluorescent Probe for Uridine Diphosphate Glucuronosyltransferase 1A1: A Good Surrogate for Bilirubin.

Guangbo Ge, Ling Yang, Jingnan Cui, 2017, Journal of medicinal chemistry.

Selectivity for inhibition of nilotinib on the catalytic activity of human UDP-glucuronosyltransferases

Guangbo Ge, Liangliang Zhu, Yun-feng Cao, 2014, Xenobiotica; the fate of foreign compounds in biological systems.

Substrate-dependent modulation of the catalytic activity of CYP3A by erlotinib

Yan-Yan Zhang, Guangbo Ge, Ling Yang, 2011, Acta Pharmacologica Sinica.

Highly sensitive and selective detection of human carboxylesterase 1 activity by liquid chromatography with fluorescence detection.

Guangbo Ge, Ling Yang, Qi Zhou, 2016, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Transcriptional regulation of G2/M regulatory proteins and perturbation of G2/M Cell cycle transition by a traditional Chinese medicine recipe.

N. Suchowerska, H. Nie, P. de Souza, 2019, Journal of ethnopharmacology.

Regioselective Glucuronidation of Andrographolide and Its Major Derivatives: Metabolite Identification, Isozyme Contribution, and Species Differences

Guangbo Ge, Ling Yang, Xiaochi Ma, 2015, The AAPS Journal.

Identifying and applying a highly selective probe to simultaneously determine the O-glucuronidation activity of human UGT1A3 and UGT1A4

Guangbo Ge, Xiaochi Ma, Xiaokui Huo, 2015, Scientific Reports.

Deciphering the metabolic fates of a green fluorescent protein (GFP)-like fluorophore: Metabolite identification, isoenzyme contribution and species differences

Guangbo Ge, Ling Yang, Yue-Lai Chen, 2020 .

Rational design of a novel aptamer-based biosensor for a target enzyme via modification of GFP-like fluorogens: Carboxylesterase 2A as a case study

Qinghui Tang, Guangbo Ge, Yue-Lai Chen, 2020 .

An optimized ratiometric fluorescent probe for sensing human UDP-glucuronosyltransferase 1A1 and its biological applications.

M. Finel, Guangbo Ge, Ling Yang, 2015, Biosensors & bioelectronics.

Identification and characterization of human UDP-glucuronosyltransferases responsible for the glucuronidation of fraxetin.

Sheng-Li Yang, Guangbo Ge, Ling Yang, 2014, Drug metabolism and pharmacokinetics.

Determination of propofol UDP-glucuronosyltransferase (UGT) activities in hepatic microsomes from different species by UFLC-ESI-MS.

Guangbo Ge, Ling Yang, Z. Fang, 2011, Journal of pharmaceutical and biomedical analysis.

Flavonoids in Ampelopsis grossedentata as covalent inhibitors of SARS-CoV-2 3CLpro: Inhibition potentials, covalent binding sites and inhibitory mechanisms

Guangbo Ge, Guanghao Zhu, Yuan Xiong, 2021, International Journal of Biological Macromolecules.

Prediction of ligand modulation patterns on membrane receptors via lysine reactivity profiling.

Fangjun Wang, Tongyi Dou, Zheyi Liu, 2019, Chemical communications.

Isolation and characterization of a novel α-glucosidase with transglycosylation activity from Arthrobacter sp. DL001

Guangbo Ge, Ling Yang, Xiaochi Ma, 2012 .

A novel substrate-inspired fluorescent probe to monitor native albumin in human plasma and living cells.

Guangbo Ge, Ling Yang, Xinyue Zhu, 2017, Analytica chimica acta.

Highly selective and efficient biotransformation of linarin to produce tilianin by naringinase

Tongyi Dou, Ping Wang, Guangbo Ge, 2016, Biotechnology Letters.

Biotransformation of Glycoginsenosides to Intermediate Products and Aglycones using a Hemicellulosome Produced by Cellulosimicrobium cellulan

Tongyi Dou, Guangbo Ge, J. Chen, 2019, Applied Biochemistry and Microbiology.

Identification of cytochrome P450 (CYP) isoforms involved in the metabolism of corynoline, and assessment of its herb–drug interactions

Yan-Yan Zhang, Guangbo Ge, Ling Yang, 2011, Phytotherapy research : PTR.

Ginsenoside Metabolites Inhibit P-Glycoprotein In Vitro and In Situ Using Three Absorption Models

Guangbo Ge, Xiuli Wang, Yong Liu, 2014, Planta Medica.

Rapid qualitative and quantitative determination of seven valuable taxanes from various Taxus species by UFLC-ESI-MS and UFLC-DAD.

Yan-Yan Zhang, Guangbo Ge, Ling Yang, 2010, Planta medica.

Interspecific relationships and origins of Taxaceae and Cephalotaxaceae revealed by partitioned Bayesian analyses of chloroplast and nuclear DNA sequences

P. Xiao, Guangbo Ge, Ling Yang, 2008, Plant Systematics and Evolution.

Deep understanding of the interaction between thienorphine and UDP-glucuronosyltransferase (UGT) isoforms

Guangbo Ge, Ling Yang, Z. Fang, 2013, Xenobiotica; the fate of foreign compounds in biological systems.

Rapid profiling and target analysis of principal components in Fuling Decoctions by UFLC-DAD-ESI-MS.

Ling Yang, Ao-Xue Wang, Guang-Bo Ge, 2010, Fitoterapia.

Methylophiopogonanone A is a naturally occurring broad‐spectrum inhibitor against human UDP‐glucuronosyltransferases: Inhibition behaviours and implication in herb‐drug interactions

Guangbo Ge, Guanghao Zhu, Yunqing Song, 2021, Basic & clinical pharmacology & toxicology.

Discovery and characterization of amentoflavone as a naturally occurring inhibitor against the bile salt hydrolase produced by Lactobacillus salivarius.

Chun Xing Li, Guangbo Ge, Yunqing Song, 2022, Food & function.

Editorial: Pharmacokinetics of herbal medicines and herb-drug interactions

G. Lin, Guangbo Ge, Chuang Lu, 2022, Frontiers in Pharmacology.

Glucuronidation of aurantio-obtusin: identification of human UDP-glucuronosyltransferases and species differences

Guangbo Ge, Zhen-qiu Zhang, Xiaoyan Gao, 2014, Xenobiotica; the fate of foreign compounds in biological systems.

Identification of human UDP-glucuronosyltransferase isoforms involved in the isofraxidin glucuronidation and assessment of the species differences of the reaction.

Guangbo Ge, G. He, Shu-min Liu, 2017, Fitoterapia.

Functional and structural properties of a novel cellulosome-like multienzyme complex: efficient glycoside hydrolysis of water-insoluble 7-xylosyl-10-deacetylpaclitaxel

Tongyi Dou, Guangbo Ge, Ling Yang, 2015, Scientific Reports.

Chalcone derivatives as novel, potent and selective inhibitors against human Notum: Structure–activity relationships and biological evaluations

Guangbo Ge, Yunqing Song, Meng-Ru Sun, 2023, Chinese Chemical Letters.

Synthesis and biological evaluation of esculetin derivatives as potential anti-HBV agents

Guangbo Ge, Tong Zhao, Z. Ye, 2023, Medicinal Chemistry Research.

Construction and application of a high-content analysis for identifying human carboxylesterase 2 inhibitors in living cell system

Guangbo Ge, Ling Yang, Q. Jin, 2020, Analytical and Bioanalytical Chemistry.

Rational construction of a practical enzyme-activatable fluorogenic substrate for hNotum and its applications in functional imaging and inhibitor screening

Guangbo Ge, Zhenhao Tian, Yunqing Song, 2023, Sensors and Actuators B: Chemical.

In vitro characterization of the glucuronidation pathways of licochalcone A mediated by human UDP-glucuronosyltransferases

Tongyi Dou, Guangbo Ge, X. Lv, 2018, Xenobiotica; the fate of foreign compounds in biological systems.

Efficient enzymatic preparation of esculentoside B following condition optimization by response surface methodology

Tongyi Dou, Guangbo Ge, Ling Yang, 2016 .

Recent progress and challenges in screening and characterization of UGT1A1 inhibitors

M. Finel, Guangbo Ge, Ling Yang, 2018, Acta pharmaceutica Sinica. B.

Human carboxylesterase 1A plays a predominant role in hydrolysis of the anti-dyslipidemia agent fenofibrate in humans.

Hong-xin Li, Guangbo Ge, Xu-Dong Hou, 2023, Drug metabolism and disposition: the biological fate of chemicals.

A Two-Photon Ratiometric Fluorescent Probe for Imaging Carboxylesterase 2 in Living Cells and Tissues.

Guangbo Ge, Ling Yang, Zhi-Hong Liu, 2015, ACS applied materials & interfaces.

New insights for the risk of bisphenol A: inhibition of UDP-glucuronosyltransferases (UGTs).

Yan-Yan Zhang, Guangbo Ge, Ling Yang, 2013, Chemosphere.

Target Enzyme‐Activated Two‐Photon Fluorescent Probes: A Case Study of CYP3A4 Using a Two‐Dimensional Design Strategy

T. James, Guangbo Ge, Xiaochi Ma, 2019, Angewandte Chemie.

Licochalcone A Derivatives as Selective Dipeptidyl Peptidase 4 Inhibitors with Anti-Inflammatory Effects.

Guangbo Ge, Li-Wei Zou, Jinhui Shi, 2023, Journal of natural products.

Time-dependent inhibition (TDI) of CYP3A4 and CYP2C9 by noscapine potentially explains clinical noscapine-warfarin interaction.

Yan-Yan Zhang, Guangbo Ge, Ling Yang, 2010, British journal of clinical pharmacology.

A highly selective probe for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human microsomes: isoform specificity, kinetic characterization, and applications

Guangbo Ge, Xiaochi Ma, Xiangge Tian, 2015 .

Comparative Metabolism of Cinobufagin in Liver Microsomes from Mouse, Rat, Dog, Minipig, Monkey, and Human

Guangbo Ge, Ling Yang, Xiaochi Ma, 2011, Drug Metabolism and Disposition.

Drug Metabolism and Disposition: DMD-AR-2023-001365R1 Human carboxylesterase 1A plays a predominant role in hydrolysis of the anti-dyslipidemia agent fenofibrate in humans

Hong-xin Li, Guangbo Ge, Xu-Dong Hou, 2023 .

An expedient method for regioselective methylation of catechol coumarins

Guangbo Ge, Ling Yang, J. Hou, 2016, Chemical Research in Chinese Universities.