Kang-Choon Lee

发表

The fatty acid conjugated exendin-4 analogs for type 2 antidiabetic therapeutics.

D. S. Lee, S. Chae, Sohee Son, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Long acting hyaluronate--exendin 4 conjugate for the treatment of type 2 diabetes.

S. Chae, S. Hahn, E. J. Oh, 2010, Biomaterials.

Multiplex imaging of an intracellular proteolytic cascade by using a broad-spectrum nanoquencher.

Kwangmeyung Kim, Jinwoo Park, K. Choi, 2012, Angewandte Chemie.

PEGylated TRAIL ameliorates experimental inflammatory arthritis by regulation of Th17 cells and regulatory T cells

M. Pomper, D. Jo, Yumin Oh, 2017, Journal of controlled release : official journal of the Controlled Release Society.

Functionalized injectable hydrogels for controlled insulin delivery.

D. S. Lee, S. Chae, Kang-Choon Lee, 2008, Biomaterials.

In situ facile-forming PEG cross-linked albumin hydrogels loaded with an apoptotic TRAIL protein.

Eun Seong Lee, B. Shin, Han‐Gon Choi, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Long-acting inhalable chitosan-coated poly(lactic-co-glycolic acid) nanoparticles containing hydrophobically modified exendin-4 for treating type 2 diabetes

Eun Seong Lee, Y. Youn, K. Oh, 2013, International journal of nanomedicine.

Thiolated Glycol Chitosan Bearing α-Cyclodextrin for Sustained Delivery of PEGylated Human Growth Hormone

D. Jo, J. Park, S. Chae, 2012, Journal of biomaterials science. Polymer edition.

Pharmacokinetics of a novel histone deacetylase inhibitor, apicidin, in rats

B. Shin, Kang-Choon Lee, O. Zee, 2006, Biopharmaceutics & drug disposition.

Inhibition of Notch signalling ameliorates experimental inflammatory arthritis

M. Mattson, Kwangmeyung Kim, T. Arumugam, 2013, Annals of the rheumatic diseases.

Ionic complex systems based on hyaluronic acid and PEGylated TNF-related apoptosis-inducing ligand for treatment of rheumatoid arthritis.

Kwangmeyung Kim, I. Kwon, D. Jo, 2010, Biomaterials.

Oral Absorption and Pharmacokinetics of Rebamipide and Rebamipide Lysinate in Rats

B. Shin, Kang-Choon Lee, Chi Ho Yoon, 2004, Drug development and industrial pharmacy.

Dual mechanistic TRAIL nanocarrier based on PEGylated heparin taurocholate and protamine which exerts both pro-apoptotic and anti-angiogenic effects.

Seung Woo Chung, Y. Byun, Ji-Young Kim, 2021, Journal of controlled release : official journal of the Controlled Release Society.

Delivery of tumor-homing TRAIL sensitizer with long-acting TRAIL as a therapy for TRAIL-resistant tumors.

M. Pomper, Kwangmeyung Kim, M. Swierczewska, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Doxorubicin-Bound Albumin Nanoparticles Containing a TRAIL Protein for Targeted Treatment of Colon Cancer

Eun Seong Lee, Han‐Gon Choi, Y. Youn, 2015, Pharmaceutical Research.

Evaluation of interstitial protein delivery in multicellular layers model

Soo-Yeon Kim, K. Park, H. Kuh, 2012, Archives of Pharmacal Research.

Doxorubicin-loaded human serum albumin nanoparticles surface-modified with TNF-related apoptosis-inducing ligand and transferrin for targeting multiple tumor types.

Eun Seong Lee, Y. Youn, K. Oh, 2012, Biomaterials.

PEGylated TNF-related apoptosis-inducing ligand (TRAIL)-loaded sustained release PLGA microspheres for enhanced stability and antitumor activity.

Xiaoyuan Chen, Seulki Lee, Y. Youn, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Improved Antitumor Activity and Tumor Targeting of NH2-Terminal–Specific PEGylated Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand

Kwangmeyung Kim, I. Kwon, D. Jo, 2010, Molecular Cancer Therapeutics.

The synthesis of tamoxifen-loaded albumin nanoparticles by homogenizers: Optimization and in vitro characterization

F. Dorkoosh, Kang-Choon Lee, S. Shojaosadati, 2017 .

Facile one-pot formulation of TRAIL-embedded paclitaxel-bound albumin nanoparticles for the treatment of pancreatic cancer.

Eun Seong Lee, B. Shin, Han‐Gon Choi, 2015, International journal of pharmaceutics.

Controlled release of insulin from pH/temperature-sensitive injectable pentablock copolymer hydrogel.

D. S. Lee, S. Chae, Kang-Choon Lee, 2009, Journal of controlled release : official journal of the Controlled Release Society.

Pharmacokinetic scaling of bisphenol A by species-invariant time methods

B. Shin, Hyung Sik Kim, Kang-Choon Lee, 2002, Xenobiotica; the fate of foreign compounds in biological systems.

Improved peroral delivery of glucagon-like peptide-1 by site-specific biotin modification: design, preparation, and biological evaluation.

S. Chae, Seulki Lee, Y. Youn, 2008, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Stability and bioactivity of nanocomplex of TNF-related apoptosis-inducing ligand.

Kwangmeyung Kim, I. Kwon, J. Park, 2008, International journal of pharmaceutics.

Preparation and stability of poly(ethylene glycol) (PEG)ylated octreotide for application to microsphere delivery

Kang-Choon Lee, D. Na, P. Deluca, 2003, AAPS PharmSciTech.

Native and Aluminum Chelate Fluorescence of 2-(Substituted anilino) nicotinic Acids

Kang-Choon Lee, S. Min, Y. J. Lee, 1982 .

Fluorescence of 2-(substituted anilino) benzoic acids and their metal chelate compounds

Kang-Choon Lee, S. Min, Y. J. Lee, 1981 .

Hydrophilic interaction chromatography-tandem mass spectrometric analysis of irbesartan in human plasma: application to pharmacokinetic study of irbesartan.

E. Park, Kang-Choon Lee, H. Lee, 2009, Journal of separation science.

Apoptotic activity and antitumor efficacy of PEGylated TNF-related apoptosis-inducing ligand (TRAIL) in a Mia Paca-2 cell-xenografted mouse model.

Seong Ho Choi, Eun Seong Lee, Y. Youn, 2014, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Four-arm PEG cross-linked hyaluronic acid hydrogels containing PEGylated apoptotic TRAIL protein for treating pancreatic cancer.

Seong Ho Choi, Eun Seong Lee, B. Shin, 2014, Acta biomaterialia.

Preparation and characterization of water-soluble albumin-bound curcumin nanoparticles with improved antitumor activity.

Xiaoyuan Chen, Seulki Lee, Y. Youn, 2011, International journal of pharmaceutics.

Application of Sodium Dodecyl Sulfate-Capillary Gel Electrophoresis to the Characterization of Ricin A-Chain Immunotoxins

Kang-Choon Lee, D. Na, Eun Ji Park, 2012, Chromatographia.

Chemical chaperone-conjugated exendin-4 as a cytoprotective agent for pancreatic β-cells.

Sohee Son, Kang-Choon Lee, D. Na, 2018, The international journal of biochemistry & cell biology.

High-yield production of biologically active mono-PEGylated salmon calcitonin by site-specific PEGylation.

Y. Youn, Kang-Choon Lee, D. Na, 2007, Journal of controlled release : official journal of the Controlled Release Society.

Improved intestinal delivery of salmon calcitonin by Lys18-amine specific PEGylation: stability, permeability, pharmacokinetic behavior and in vivo hypocalcemic efficacy.

S. Oh, Y. Youn, Kang-Choon Lee, 2006, Journal of controlled release : official journal of the Controlled Release Society.

Isolation, Characterization, and Stability of Positional Isomers of Mono-PEGylated Salmon Calcitonins

Kang-Choon Lee, D. Na, S. Yoo, 1999, Pharmaceutical Research.

Degradation of Synthetic Salmon Calcitonin in Aqueous Solution

Kang-Choon Lee, Y. J. Lee, Hyun Myo Song, 1992, Pharmaceutical Research.

Post-column fluorescence HPLC for salmon calcitonin formulations

Chong-K. Kim, Kang-Choon Lee, P. Deluca, 1995 .

Drug delivery: Brushing off antigenicity

Seulki Lee, Kang-Choon Lee, 2017, Nature Biomedical Engineering.

Cytotoxicity of anti-CALLA monoclonal antibody conjugates to methotrexate

Kang-Choon Lee, Chang Chun, 1993 .

Carbohydrate-specifically polyethylene glycol-modified ricin A-chain with improved therapeutic potential.

Soo-Chang Song, Y. Youn, Kang-Choon Lee, 2005, The international journal of biochemistry & cell biology.

Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease

Z. Mari, B. Barres, V. Roschke, 2018, Nature Medicine.

Improved biological half-life and anti-tumor activity of TNF-related apoptosis-inducing ligand (TRAIL) using PEG-exposed nanoparticles.

Xiaoyuan Chen, Seulki Lee, Kang-Choon Lee, 2011, Biomaterials.

Site-specific PEGylated Exendin-4 modified with a high molecular weight trimeric PEG reduces steric hindrance and increases type 2 antidiabetic therapeutic effects.

Y. Byun, K. Choi, Xiaoyuan Chen, 2012, Bioconjugate chemistry.

PEGylated TNF-related apoptosis-inducing ligand (TRAIL) for effective tumor combination therapy.

Xiaoyuan Chen, Seulki Lee, Y. Youn, 2011, Biomaterials.

Physicochemical characterization of poly(L-lactic acid) and poly(D,L-lactide-co-glycolide) nanoparticles with polyethylenimine as gene delivery carrier.

I. Oh, Kang-Choon Lee, Yu-mi Park, 2005, International journal of pharmaceutics.

Doxorubicin-loaded porous PLGA microparticles with surface attached TRAIL for the inhalation treatment of metastatic lung cancer.

Eun Seong Lee, B. Shin, Y. Youn, 2013, Biomaterials.

Albumin-Coated Porous Hollow Poly(Lactic-co-Glycolic Acid) Microparticles Bound with Palmityl-Acylated Exendin-4 as a Long-Acting Inhalation Delivery System for the Treatment of Diabetes

Eun Seong Lee, Y. Bae, Hyunuk Kim, 2011, Pharmaceutical Research.

Highly porous large poly(lactic-co-glycolic acid) microspheres adsorbed with palmityl-acylated exendin-4 as a long-acting inhalation system for treating diabetes.

Eun Seong Lee, Hyunuk Kim, Y. Youn, 2011, Biomaterials.

Pharmaceutical Potential of Gelatin as a pH-responsive Porogen for Manufacturing Porous Poly(d,l-lactic-co-glycolic acid) Microspheres

Hyunuk Kim, Y. Youn, K. Oh, 2010 .

Preparation of Highly Porous Poly(d,l-lactic-co-glycolic acid) (PLGA) Microspheres

Y. Youn, Kang-Choon Lee, Eun-Seong Lee, 2009 .

Biochemical, pharmaceutical and therapeutic properties of long-acting lithocholic acid derivatized exendin-4 analogs.

Y. Byun, Myung-Shik Lee, S. Chae, 2010, Journal of controlled release : official journal of the Controlled Release Society.

MATERNAL-FETAL DISPOSITION OF BISPHENOL A IN PREGNANT SPRAGUE-DAWLEY RATS

B. Shin, Hyung Sik Kim, B. Lee, 2002, Journal of toxicology and environmental health. Part A.

Hyaluronic acid-tumor necrosis factor-related apoptosis-inducing ligand conjugate for targeted treatment of liver fibrosis.

S. Hahn, W. Kong, Kang-Choon Lee, 2015, Acta biomaterialia.

Evaluation of PEGylated exendin-4 released from poly (lactic-co-glycolic acid) microspheres for antidiabetic therapy.

Kang-Choon Lee, S. Lim, H. Eom, 2015, Journal of pharmaceutical sciences.

Low molecular weight (1 kDa) polyethylene glycol conjugation markedly enhances the hypoglycemic effects of intranasally administered exendin-4 in type 2 diabetic db/db mice.

Y. Youn, Kang-Choon Lee, S. Lim, 2012, Biological & pharmaceutical bulletin.

Mono-PEGylated dimeric exendin-4 as high receptor binding and long-acting conjugates for type 2 anti-diabetes therapeutics.

Y. Byun, Xiaoyuan Chen, Seulki Lee, 2011, Bioconjugate chemistry.

On-line trace enrichment for the determination of insulin in biological samples using reversed-phase high performance liquid chromatography with column switching

Kang-Choon Lee, H. Lee, Hee-Yong Lee, 1994 .

Capillary electrophoresis to characterize ricin and its subunits with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Y. Youn, Kang-Choon Lee, D. Na, 2004, Toxicon : official journal of the International Society on Toxinology.

Assessment of biodegradability of polymeric microspheresin vivo: Poly (DL-lactic acid), poly (L-lactic acid) and poly (DL-lactide-co-glycolide) microspheres

I. Oh, Kang-Choon Lee, Jhin Yee Oh, 1993 .

Effect of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand on the Reduction of Joint Inflammation in Experimental Rheumatoid Arthritis

E. Lee, Yeong-Wook Song, D. Jo, 2010, Journal of Pharmacology and Experimental Therapeutics.

Mono-lithocholated exendin-4-loaded glycol chitosan nanoparticles with prolonged antidiabetic effects.

Kwangmeyung Kim, S. Chae, Sohee Son, 2015, International journal of pharmaceutics.

Pulmonary administered palmitic-acid modified exendin-4 peptide prolongs hypoglycemia in type 2 diabetic db/db mice

Eun Seong Lee, H. Moon, S. Chi, 2012, Regulatory Peptides.

Preparation and characterization of Apo2L/TNF-related apoptosis-inducing ligand-loaded human serum albumin nanoparticles with improved stability and tumor distribution.

Y. Youn, Kang-Choon Lee, S. Lim, 2011, Journal of pharmaceutical sciences.

Preparation and structural, biochemical, and pharmaceutical characterizations of bile acid-modified long-acting exendin-4 derivatives.

S. Chae, Seulki Lee, Sohee Son, 2009, Journal of medicinal chemistry.

Monitoring of peptide acylation inside degrading PLGA microspheres by capillary electrophoresis and MALDI-TOF mass spectrometry.

Y. Youn, Kang-Choon Lee, M. Son, 2003, Journal of controlled release : official journal of the Controlled Release Society.

Self-assembled glycol chitosan nanogels containing palmityl-acylated exendin-4 peptide as a long-acting anti-diabetic inhalation system.

Eun Seong Lee, B. Shin, S. Chi, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Human serum albumin-TRAIL conjugate for the treatment of rheumatoid arthritis.

Eun Seong Lee, B. Shin, Y. Youn, 2014, Bioconjugate chemistry.

Pharmacokinetics of 125I-GST-TatdMt, a recombinant fusion protein possessing potent anti-obesity activity, after intravenous, nasal, oral, and subcutaneous administration

M. Hur, B. Shin, Y. Youn, 2007, Regulatory Peptides.

β-cyclodextrin-bearing glycol chitosan for long-acting formulation of an exenatide derivative

D. Jo, J. Park, J. Jeong, 2014, Macromolecular Research.

What is the future of PEGylated therapies?

M. Swierczewska, Kang-Choon Lee, Seulki Lee, 2015, Expert opinion on emerging drugs.

Application of microchip CGE for the analysis of PEG‐modified recombinant human granulocyte‐colony stimulating factors

Kang-Choon Lee, D. Na, Eun Ji Park, 2010, Electrophoresis.

Evaluation of transferrin-polyethylenimine conjugate for targeted gene delivery

I. Oh, Yong Bok Lee, Kang-Choon Lee, 2005, Archives of pharmacal research.

Capillary electrophoretic characterization of PEGylated human parathyroid hormone with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Kang-Choon Lee, D. Na, 2004, Analytical biochemistry.

Synthesis, characterization, and pharmacokinetic studies of PEGylated glucagon-like peptide-1.

Y. Byun, S. Chae, Seulki Lee, 2005, Bioconjugate chemistry.

Mix to validate: a facile, reversible PEGylation for fast screening of potential therapeutic proteins in vivo.

M. Pomper, Y. Byun, D. Jo, 2013, Angewandte Chemie.

Gastroretentive drug delivery system of DA-6034, a new flavonoid derivative, for the treatment of gastritis.

Sung Hyun Park, Kang-Choon Lee, D. Na, 2008, International journal of pharmaceutics.

Immobilization of Arg-Gly-Asp (RGD) sequence in sugar containing copolymer for culturing of pheochromocytoma (PC12) cells.

K. Na, Keun-Hong Park, Kang-Choon Lee, 2004, Journal of bioscience and bioengineering.

Effect of PEGylation on stability of peptide in poly(lactide-co-glycolide) microspheres

Kang-Choon Lee, D. Na, Eun Ji Park, 2010, Archives of pharmacal research.

In vitro release study of mono-PEGylated growth hormone-releasing peptide-6 from PLGA microspheres.

Kang-Choon Lee, D. Na, Eun Ji Park, 2007, International journal of pharmaceutics.

Determination of metoclopramide in human plasma using hydrophilic interaction chromatography with tandem mass spectrometry.

E. Park, Kang-Choon Lee, H. Lee, 2009, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Liquid chromatography-tandem mass spectrometry method for the determination of meloxicam and its metabolite 5-carboxymeloxicam in human plasma.

Kang-Choon Lee, H. Lee, H. Ji, 2009, Bioanalysis.

Hydrophilic interaction chromatography-tandem mass spectrometry of donepezil in human plasma: Application to a pharmacokinetic study of donepezil in volunteers

E. Park, Kang-Choon Lee, Mann-Hyung Lee, 2008, Archives of pharmacal research.

Analysis of carvedilol in human plasma using hydrophilic interaction liquid chromatography with tandem mass spectrometry.

Y. Youn, Kang-Choon Lee, H. Lee, 2007, Journal of pharmaceutical and biomedical analysis.

Determination of gabapentin in human plasma using hydrophilic interaction liquid chromatography with tandem mass spectrometry.

Kang-Choon Lee, H. Lee, H. Ji, 2006, Rapid communications in mass spectrometry : RCM.

Emerging PEGylated drugs

Kang-Choon Lee, P. Deluca, J. Kang, 2009, Expert opinion on emerging drugs.

Capillary electrophoretic separation of high-molecular-weight poly(ethylene glycol)-modified proteins.

Kang-Choon Lee, D. Na, Eun Ji Park, 2008, Analytical biochemistry.

Effect of 2-hydroxypropyl-β-cyclodextrin on the stability of prostaglandin E2 in solution

I. Oh, Kang-Choon Lee, Hyun Myo Song, 1994 .

Separation of positional isomers of mono-poly(ethylene glycol)-modified octreotides by reversed-phase high-performance liquid chromatography.

Kang-Choon Lee, D. Na, Eun Ji Park, 2009, Journal of chromatography. A.

A new sesquiterpene lactone fromArtemisia rubripes nakai

H. Kwon, Kang-Choon Lee, K. Lee, 2004, Archives of pharmacal research.

Interspecies comparison of the oral absorption of itraconazole in laboratory animals

Beom Soo Shin, B. Shin, Kang-Choon Lee, 2002, Archives of pharmacal research.

Phytochemical Constituens of Cirsium setidens Nakai and Their Cytotoxicity against Human Cancer Cell Lines

Won Bin Lee, H. Kwon, Kang-Choon Lee, 2008 .

Phytochemical constituens ofCirsium setidens Nakai and their cytotoxicity against human cancer cell lines

Won Bin Lee, H. Kwon, Kang-Choon Lee, 2002 .

Direct analysis of clomipramine in human plasma by microbore high performance liquid chromatography with column-switching

C. K. Jeong, Kang-Choon Lee, D. Na, 2000 .

Development and validation of a reversed-phase fluorescence HPLC method for determination of bucillamine in human plasma using pre-column derivatization with monobromobimane.

B. Shin, Y. Youn, E. Park, 2009, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Chromatographic separation and mass spectrometric identification of positional isomers of polyethylene glycol-modified growth hormone-releasing factor (1-29).

Soo-Chang Song, Y. Youn, Kang-Choon Lee, 2004, Journal of chromatography. A.

Stability of PEGylated salmon calcitonin in nasal mucosa.

J. Lee, Y. Youn, Kang-Choon Lee, 2004, Journal of pharmaceutical sciences.

Quantification of doxazosin in human plasma using hydrophilic interaction liquid chromatography with tandem mass spectrometry.

Kang-Choon Lee, Kang Choon Lee, Hye Young Ji, 2008, Journal of separation science.

Long-acting interferon-alpha 2a modified with a trimer-structured polyethylene glycol: preparation, in vitro bioactivity, in vivo stability and pharmacokinetics.

Y. Youn, Kang-Choon Lee, E. Choi, 2006, International journal of pharmaceutics.

Rapid Screening of Blood-Brain Barrier Penetration of Drugs Using the Immobilized Artificial Membrane Phosphatidylcholine Column Chromatography

Beom Soo Shin, B. Shin, Kang-Choon Lee, 2006, Journal of biomolecular screening.

Characterization of Two Ricin Isoforms by Sodium Dodecyl Sulfate-Capillary Gel Electrophoresis and Capillary Isoelectric Focusing

Kang-Choon Lee, D. Na, Eun Ji Park, 2011 .

Smad7 Protein Induces Interferon Regulatory Factor 1-dependent Transcriptional Activation of Caspase 8 to Restore Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-mediated Apoptosis

Seong-Jin Kim, Kang-Choon Lee, Tae Hyung Kim, 2012, The Journal of Biological Chemistry.

A new orally available glucagon-like peptide-1 receptor agonist, biotinylated exendin-4, displays improved hypoglycemic effects in db/db mice.

S. Chae, Sohee Son, Y. Youn, 2009, Journal of controlled release : official journal of the Controlled Release Society.

Oral Delivery of Mono-PEGylated sCT (Lys18) in Rats: Regional Difference in Stability and Hypocalcemic Effect

Y. Youn, Kang-Choon Lee, S. Mansoor, 2005, Pharmaceutical development and technology.

Preparation, characterization, and application of biotinylated and biotin-PEGylated glucagon-like peptide-1 analogues for enhanced oral delivery.

S. Chae, Seulki Lee, Y. Youn, 2008, Bioconjugate chemistry.

Optimization of the PEGylation process of a peptide by monitoring with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Y. Youn, Kang-Choon Lee, D. Na, 2003, Rapid communications in mass spectrometry : RCM.

Cancer preventive effect of recombinant TRAIL by ablation of oncogenic inflammation in colitis-associated cancer rather than anticancer effect

K. Hahm, Kang-Choon Lee, Suntaek Hong, 2017, Oncotarget.

Targeting of dermal myofibroblasts through death receptor 5 arrests fibrosis in mouse models of scleroderma

Ami A. Shah, M. Horton, M. Pomper, 2019, Nature Communications.

Emerging PEGylated non-biologic drugs

Kang-Choon Lee, D. Na, Eun Ji Park, 2019, Expert opinion on emerging drugs.

Capillary Separation Techniques

Kang-Choon Lee, D. Na, 2010 .

Preparation and evaluation of palmitic acid-conjugated exendin-4 with delayed absorption and prolonged circulation for longer hypoglycemia.

Eun Seong Lee, H. Moon, Y. Youn, 2012, International journal of pharmaceutics.

PEG-transferrin conjugated TRAIL (TNF-related apoptosis-inducing ligand) for therapeutic tumor targeting.

Y. Byun, Xiaoyuan Chen, Seulki Lee, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer’s disease

M. Pomper, J. Troncoso, T. Dawson, 2021, Acta neuropathologica communications.

PEGylated TNF-related apoptosis-inducing ligand (TRAIL) analogues: pharmacokinetics and antitumor effects.

Xiaoyuan Chen, Seulki Lee, Y. Youn, 2011, Bioconjugate chemistry.

In vivo pharmacokinetics and pharmacodynamics of positional isomers of mono-PEGylated recombinant human granulocyte colony stimulating factor in rats.

Kang-Choon Lee, J. Kang, 2013, Biological & pharmaceutical bulletin.

Monoclonal antibody-based targeting of methotrexate-loaded microspheres

C. Cha, Kang-Choon Lee, Y. J. Lee, 1990 .

Exendins and exendin analogs for diabetic therapy: a patent review (2012-2015)

Kang-Choon Lee, S. Lim, D. Na, 2016, Expert opinion on therapeutic patents.

Conjugation of heparin into carboxylated pullulan derivatives as an extracellular matrix for endothelial cell culture

K. Na, Kang-Choon Lee, K. Yun, 2003, Biotechnology Letters.

PHYSIOLOGICALLY BASED PHARMACOKINETICS OF BISPHENOL A

Beom Soo Shin, Byung Mu Lee, B. Shin, 2004, Journal of toxicology and environmental health. Part A.

Inhalable self-assembled albumin nanoparticles for treating drug-resistant lung cancer.

Seong Ho Choi, Eun Seong Lee, B. Shin, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Nasal absorption and pharmacokinetic disposition of salmon calcitonin modified with low molecular weight polyethylene glycol.

B. Shin, Kang-Choon Lee, S. Yoo, 2004, Chemical & pharmaceutical bulletin.

Improved intrapulmonary delivery of site-specific PEGylated salmon calcitonin: optimization by PEG size selection.

S. Chae, Seulki Lee, Y. Youn, 2008, Journal of controlled release : official journal of the Controlled Release Society.

Doxorubicin-Bound Albumin Nanoparticles Containing a TRAIL Protein for Targeted Treatment of Colon Cancer

Eun Seong Lee, Han‐Gon Choi, Y. Youn, 2016, Pharmaceutical Research.

Pharmacokinetic and pharmacodynamic evaluation of site-specific PEGylated glucagon-like peptide-1 analogs as flexible postprandial-glucose controllers.

Eun Seong Lee, S. Chae, Seulki Lee, 2009, Journal of pharmaceutical sciences.

Intrapulmonary potential of polyethylene glycol-modified glucagon-like peptide-1s as a type 2 anti-diabetic agent

Eun Seong Lee, S. Chae, Seulki Lee, 2009, Regulatory Peptides.

Preparation and Characterization of Salmon Calcitonin–biotin Conjugates

Y. Youn, Y. Capan, Kang-Choon Lee, 2008, AAPS PharmSciTech.

Effect of molecular size of PEGylated recombinant human epidermal growth factor on the biological activity and stability in rat wound tissue.

Y. Youn, Kang-Choon Lee, D. Na, 2006 .

PEGylation of Octreotide: II. Effect of N-terminal Mono-PEGylation on Biological Activity and Pharmacokinetics

Kang-Choon Lee, D. Na, P. Deluca, 2005, Pharmaceutical Research.

Tyrosine kinase inhibitor neratinib attenuates liver fibrosis by targeting activated hepatic stellate cells

Kwangmeyung Kim, K. Chung, Yumin Oh, 2020, Scientific Reports.

Biodegradable oligo(amidoamine/β-amino ester) hydrogels for controlled insulin delivery

D. S. Lee, S. Chae, Guanghui Gao, 2011 .

Evaluation of interstitial protein delivery in multicellular layers model

H. Kuh, Kang-Choon Lee, Tae Hyung Kim, 2012, Archives of Pharmacal Research.

Trimeric PEG-Conjugated Exendin-4 for the Treatment of Sepsis.

Wonhwa Lee, J. Bae, Kang-Choon Lee, 2016, Biomacromolecules.

Systemic PEGylated TRAIL treatment ameliorates liver cirrhosis in rats by eliminating activated hepatic stellate cells

M. Pomper, Kwangmeyung Kim, Y. Byun, 2016, Hepatology.

Synthesis and evaluation of human serum albumin-modified exendin-4 conjugate via heterobifunctional polyethylene glycol linkage with protracted hypoglycemic efficacy.

Eun Seong Lee, Y. Youn, K. Oh, 2010, Bioconjugate chemistry.

Reducing agent-free synthesis of curcumin-loaded albumin nanoparticles by self-assembly at room temperature.

Kang-Choon Lee, S. Shojaosadati, D. Na, 2017, International journal of pharmaceutics.

A sulfate polysaccharide/TNF‐related apoptosis‐inducing ligand (TRAIL) complex for the long‐term delivery of TRAIL in poly(lactic‐co‐glycolic acid) (PLGA) microspheres

K. Na, Dooyong Jeong, Kang-Choon Lee, 2013, The Journal of pharmacy and pharmacology.

Biological and physicochemical evaluation of the conformational stability of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)

S. Chae, Y. Youn, Kang-Choon Lee, 2007, Biotechnology Letters.

Degradation kinetics of growth hormone-releasing hexapeptide (GHRP-6) in aqueous solution

Kang-Choon Lee, B. H. Woo, K. K. Tak, 1996 .

Size and morphological analysis of albumin microspheres in the lungs and liver of mice

Kang-Choon Lee, Y. J. Lee, I. Koh, 1988 .

Phytochemical constituents of Cirsium setidens Nakai and their cytotoxicity against human cancer cell lines.

Won Bin Lee, H. Kwon, Kang-Choon Lee, 2002, Archives of pharmacal research.

Preparation and Characterization of Self-assembled Glycol Chitosan Hydrogels Containing Palmityl-acylated Exendin-4 for Extended Hypoglycemic Action

Eun Seong Lee, Y. Youn, K. Oh, 2011 .

Evaluation of therapeutic potentials of site-specific PEGylated glucagon-like peptide-1 isomers as a type 2 anti-diabetic treatment: Insulinotropic activity, glucose-stabilizing capability, and proteolytic stability.

S. Chae, Seulki Lee, Y. Youn, 2007, Biochemical pharmacology.

Physicochemical characterization and in vivo evaluation of poloxamer-based solid suppository containing diclofenac sodium in rats.

Y. Oh, Dae-Duk Kim, Han‐Gon Choi, 2005, International journal of pharmaceutics.

Reversible Blocking of Amino Groups of Octreotide for the Inhibition of Formation of Acylated Peptide Impurities in Poly(Lactide-co-Glycolide) Delivery Systems

Kang-Choon Lee, D. Na, Eun Ji Park, 2011, AAPS PharmSciTech.

Doxorubicin-loaded highly porous large PLGA microparticles as a sustained- release inhalation system for the treatment of metastatic lung cancer.

Insoo Kim, Beom Soo Shin, Eun Seong Lee, 2012, Biomaterials.

Formation of acylated growth hormone-releasing peptide-6 by poly(lactide-co-glycolide) and its biological activity

Kang-Choon Lee, Jeong Eun Lee, D. Na, 2007, AAPS PharmSciTech.

Direct determination of the peptide content in microspheres by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Kang-Choon Lee, D. Na, P. Deluca, 2004, Analytical Chemistry.

Sodium dodecyl sulfate‐capillary gel electrophoresis of polyethylene glycolylated interferon alpha

Y. Youn, Kang-Choon Lee, D. Na, 2004, Electrophoresis.

Pharmacokinetic scaling of SJ‐8029, a novel anticancer agent possessing microtubule and topoisomerase inhibiting activities, by species‐invariant time methods

B. Shin, Kang-Choon Lee, S. Yoo, 2003, Biopharmaceutics & drug disposition.

BIOAVAILABILITY AND MAMMARY EXCRETION OF BISPHENOL A IN SPRAGUE-DAWLEY RATS

B. Shin, Hyung Sik Kim, B. Lee, 2001, Journal of toxicology and environmental health. Part A.

Site-specific PEGylation for high-yield preparation of Lys(21)-amine PEGylated growth hormone-releasing factor (GRF) (1-29) using a GRF(1-29) derivative FMOC-protected at Tyr(1) and Lys(12).

Y. Youn, Kang-Choon Lee, 2007, Bioconjugate chemistry.

Liquid chromatography-mass spectrometric method for the sensitive determination of niflumic acid in human plasma and its application to pharmacokinetic study of talniflumate tablet.

Kang-Choon Lee, D. Na, Eun Ji Park, 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Improved HPLC Method for the Determination of Niflumic Acid in Human Plasma and Its Application to a Bioequivalence Study of Talniflumate Tablets

Kang-Choon Lee, D. Na, Eun Ji Park, 2008 .

Systemic PEGylated TRAIL treatment ameliorates liver cirrhosis in rats by eliminating activated hepatic stellate cells

M. Pomper, Kwangmeyung Kim, Y. Byun, 2016, Hepatology.

Functionalized injectable hydrogels for controlled insulin delivery.

D. S. Lee, S. Chae, Kang-Choon Lee, 2008, Biomaterials.

The fatty acid conjugated exendin-4 analogs for type 2 antidiabetic therapeutics.

D. S. Lee, S. Chae, Sohee Son, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Dose-linear pharmacokinetics, tissue distribution, and excretion of a recombinant fusion protein 125I-GST-TatdMt possessing potent anti-obesity activity

M. Hur, B. Shin, Kang-Choon Lee, 2005, Regulatory Peptides.

Long acting hyaluronate--exendin 4 conjugate for the treatment of type 2 diabetes.

S. Chae, S. Hahn, Kang-Choon Lee, 2010, Biomaterials.

Preparation and characterization of water-soluble albumin-bound curcumin nanoparticles with improved antitumor activity.

Xiaoyuan Chen, Seulki Lee, Y. Youn, 2011, International journal of pharmaceutics.

Synthesis, characterization, and pharmacokinetic studies of PEGylated glucagon-like peptide-1.

Y. Byun, S. Chae, Y. Youn, 2005, Bioconjugate chemistry.

A 4-arm polyethylene glycol derivative conjugated with exendin-4 peptide and palmitylamine having dual-function of size-increase and albumin-binding for long hypoglycemic action

Eun Seong Lee, Y. Youn, K. Oh, 2011, Regulatory Peptides.

Ricin A immunotoxins of IgG and Fab of anti-CALLA monoclonal antibody: Effect of water soluble long-chain SPDP on conjugate yield, immunoselectivity and cytotoxicity

Kang-Choon Lee, Jung Tae Lee, B. Woo, 1994, Archives of pharmacal research.

Effect of PEGylation on stability of peptide in poly(lactide-co-glycolide) microspheres

Kang-Choon Lee, D. Na, Eun Ji Park, 2010, Archives of pharmacal research.

Effect of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand on the Reduction of Joint Inflammation in Experimental Rheumatoid Arthritis

E. Lee, D. Jo, S. Chae, 2010, Journal of Pharmacology and Experimental Therapeutics.

Preparation and Evaluation of a 4-Branched Polyethylene Glycol Derivative Modified with Exendin-4 and Stearylamine for Extended Hypoglycemic Action

Y. Youn, K. Oh, Kang-Choon Lee, 2010 .

Decanoic acid-modified glycol chitosan hydrogels containing tightly adsorbed palmityl-acylated exendin-4 as a long-acting sustained-release anti-diabetic system.

Eun Seong Lee, Y. Youn, K. Oh, 2014, Acta biomaterialia.