Dongyang Liu

发表

A unified strategy in selection of the best allometric scaling methods to predict human clearance based on drug disposition pathway

Dongyang Liu, Hanlin Song, Ling Song, 2016, Xenobiotica; the fate of foreign compounds in biological systems.

In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

Xu Liu, Siyan Zhan, Wenjie Tan, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Relative contributions of the major human CYP450 to the metabolism of icotinib and its implication in prediction of drug–drug interaction between icotinib and CYP3A4 inhibitors/inducers using physiologically based pharmacokinetic modeling

Dongyang Liu, Ji Jiang, P. Hu, 2015, Expert opinion on drug metabolism & toxicology.

Comprehensive PBPK model to predict drug interaction potential of Zanubrutinib as a victim or perpetrator

Dongyang Liu, Y. Ou, S. Sahasranaman, 2021, CPT: pharmacometrics & systems pharmacology.

Current trends in drug metabolism and pharmacokinetics

Z. Zuo, Xiaoyan Chen, A. Yu, 2019, Acta pharmaceutica Sinica. B.

Response to Jia and Wang

Dongyang Liu, Xueting Yao, Miao Zhang, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Reply to Wolowich and Kwon

Dongyang Liu, Xueting Yao, Miao Zhang, 2020, Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America.

Commentary to Simulation of Drug in the Lung can be misleading.

Dongyang Liu, Xueting Yao, Miao Zhang, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Dipeptidyl-Peptidase-IV Inhibitors, Imigliptin and Alogliptin, Improve Beta-Cell Function in Type 2 Diabetes

Xinhua Xiao, Dongyang Liu, Yang Liu, 2021, Frontiers in Endocrinology.

A high‐performance liquid chromatography‐tandem mass spectrometry method for the determination of lifrafenib, a novel RAF kinase and EGFR inhibitor, in human plasma and urine and its application in clinical pharmacokinetic study

Dongyang Liu, Ling Song, Yang Liu, 2019, Journal of pharmaceutical and biomedical analysis.

Physiologically based pharmacokinetic model of renally cleared antibacterial drugs in Chinese renal impairment patients

Dongyang Liu, Xueting Yao, Miao Zhang, 2020, Biopharmaceutics & drug disposition.

Development of a physiologically based pharmacokinetic (PBPK) population model for Chinese elderly subjects

Dongyang Liu, O. Hatley, Xueting Yao, 2020, British journal of clinical pharmacology.

Development of a Physiologically Based Pharmacokinetic Model for Sinogliatin, a First-in-Class Glucokinase Activator, by Integrating Allometric Scaling, In Vitro to In Vivo Exploration and Steady-State Concentration–Mean Residence Time Methods: Mechanistic Understanding of its Pharmacokinetics

Dongyang Liu, Ling Song, Ji Jiang, 2018, Clinical Pharmacokinetics.

Translational Prediction of first-in-human Pharmacokinetics and Pharmacodynamics of janagliflozin, a selective SGLT2 inhibitor, using Allometric Scaling, Dedrick and PK/PD Modeling Methods.

Dongyang Liu, Ling Song, Yang Liu, 2020, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Development of an HPLC-MS/MS method to determine janagliflozin in human plasma and urine: application in clinical study.

Dongyang Liu, Ling Song, Yang Liu, 2018, Bioanalysis.

Safety, Pharmacokinetics, and Pharmacogenetics of Single-Dose Teriflunomide Sodium and Leflunomide in Healthy Chinese Subjects

Xia Chen, Dongyang Liu, Ji Jiang, 2019, Clinical Drug Investigation.

Clinical pharmacokinetics, safety, and preliminary efficacy evaluation of icotinib in patients with advanced non-small cell lung cancer.

Dongyang Liu, Ji Jiang, P. Hu, 2015, Lung cancer.

Therapeutic effects and adverse drug reactions are affected by icotinib exposure and CYP2C19 and EGFR genotypes in Chinese non-small cell lung cancer patients.

Dongyang Liu, Ji Jiang, P. Hu, 2014, Asian Pacific journal of cancer prevention : APJCP.

A high-performance liquid chromatography-tandem mass spectrometry method for simultaneous determination of imigliptin, its five metabolites and alogliptin in human plasma and urine and its application to a multiple-dose pharmacokinetic study.

Dongyang Liu, Ling Song, Yang Liu, 2018, Biomedical chromatography : BMC.

Pharmacokinetics and Pharmacodynamics of Vildagliptin in Healthy Chinese Volunteers

Yan-Ling He, Dongyang Liu, Ji Jiang, 2009, Journal of clinical pharmacology.

Metabolites characterization of a novel DPP‐4 inhibitor, imigliptin in humans and rats using ultra‐high performance liquid chromatography coupled with synapt high‐resolution mass spectrometry

Dongyang Liu, Ling Song, Yang Liu, 2018, Journal of pharmaceutical and biomedical analysis.

Cytotoxicity Evaluation of Chloroquine and Hydroxychloroquine in Multiple Cell Lines and Tissues by Dynamic Imaging System and Physiologically Based Pharmacokinetic Model

L. Xue, Dongyang Liu, Zhengyang Guo, 2020, Frontiers in Pharmacology.

Metabolite characterization of a novel anti-cancer agent, icotinib, in humans through liquid chromatography/quadrupole time-of-flight tandem mass spectrometry.

Dongyang Liu, Ji Jiang, P. Hu, 2011, Rapid communications in mass spectrometry : RCM.

Reduction effect of oral pravastatin on the acute phase response to intravenous zoledronic acid: protocol for a real-world prospective, placebo-controlled trial

Dongyang Liu, Chunli Song, M. Zhang, 2022, BMJ open.

Development of a Physiologically Based Pharmacokinetic Model for Hydroxychloroquine and Its Application in Dose Optimization in Specific COVID-19 Patients

J. Qiao, Dongyang Liu, Chunli Song, 2021, Frontiers in Pharmacology.

Time-Dependent Distribution of Hydroxychloroquine in Cynomolgus Macaques Using Population Pharmacokinetic Modeling Method

M. Liu, Dongyang Liu, Chunli Song, 2021, Frontiers in Pharmacology.

Population-based meta-analysis of chloroquine: informing chloroquine pharmacokinetics in COVID-19 patients

Dongyang Liu, Xueting Yao, Cheng Cui, 2020, European Journal of Clinical Pharmacology.

Dose selection of chloroquine phosphate for treatment of COVID-19 based on a physiologically based pharmacokinetic model

J. Qiao, Dongyang Liu, Chunli Song, 2020, Acta Pharmaceutica Sinica B.

Development of a Virtual Chinese Pediatric Population Physiological Model Targeting Specific Metabolism and Kidney Elimination Pathways

Dongyang Liu, F. Salem, Xueting Yao, 2021, Frontiers in Pharmacology.

Preliminary physiologically based pharmacokinetic modeling of renally cleared drugs in Chinese pregnant women

Dongyang Liu, Ling Song, T. Zhou, 2020, Biopharmaceutics & drug disposition.

Review on the clinical pharmacology of hydroxychloroquine sulfate for the treatment of COVID-19.

Dongyang Liu, Xueting Yao, Cheng Cui, 2020, Current drug metabolism.

Updates on the Pharmacology of Chloroquine against Coronavirus Disease 2019 (COVID-19): A Perspective on its Use in the General and Geriatric Population.

Dongyang Liu, Xueting Yao, Miao Zhang, 2020, Current drug metabolism.

Cytotoxicity evaluation of chloroquine and hydroxychloroquine in multiple cell lines and tissues by dynamic imaging system and PBPK model

L. Xue, Dongyang Liu, Zhengyang Guo, 2020, bioRxiv.

Quantitative determination of olmesartan in human plasma and urine by liquid chromatography coupled to tandem mass spectrometry.

Dongyang Liu, Ji Jiang, P. Hu, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Quantitative determination of atorvastatin and para-hydroxy atorvastatin in human plasma by LC-MS-MS.

Dongyang Liu, Ji Jiang, P. Hu, 2008, Journal of chromatographic science.

Quantitative determination of icotinib in human plasma and urine using liquid chromatography coupled to tandem mass spectrometry.

Dongyang Liu, Ji Jiang, P. Hu, 2009, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Simultaneous determination of TPN729 and its five metabolites in human plasma and urine by liquid chromatography coupled to tandem mass spectrometry

Dongyang Liu, Hanlin Song, Ling Song, 2018, Journal of pharmaceutical and biomedical analysis.

Simultaneous determination of imigliptin and its three metabolites in human plasma and urine by liquid chromatography coupled to tandem mass spectrometry.

Dongyang Liu, Hanlin Song, Yang Liu, 2015, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Development of population pharmacokinetics model of icotinib with non-linear absorption characters in healthy Chinese volunteers to assess the CYP2C19 polymorphism and food-intake effect

Dongyang Liu, Ji Jiang, P. Hu, 2015, European Journal of Clinical Pharmacology.

Clinical pharmacokinetics of Icotinib, an anti-cancer drug: evaluation of dose proportionality, food effect, and tolerability in healthy subjects

Dongyang Liu, Ji Jiang, P. Hu, 2014, Cancer Chemotherapy and Pharmacology.

Effect of the CYP2C19 genotype on the pharmacokinetics of icotinib in healthy male volunteers

Dongyang Liu, Ji Jiang, P. Hu, 2012, European Journal of Clinical Pharmacology.

Assessment of Aging-Related Function Variations of P-gp Transporter in Old-Elderly Chinese CHF Patients Based on Modeling and Simulation

Dongyang Liu, Cheng Cui, Haiyan Li, 2022, Clinical pharmacokinetics.

Physiologically-based pharmacokinetic modeling to predict drug-drug interactions of dabigatran etexilate and rivaroxaban in the Chinese older adults

Dongyang Liu, Cheng Cui, Haiyan Li, 2023, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Prediction of pyrotinib exposure based on physiologically-based pharmacokinetic model and endogenous biomarker

Dongyang Liu, Xueting Yao, Miao Zhang, 2022, Frontiers in Pharmacology.

Scaling Pharmacodynamics from Rats to Humans to Support Erythropoietin and Romiplostim Combination Therapy to Treat Erythropoietin-Resistant Anemia

Dongyang Liu, R. Wong, W. Krzyzanski, 2023, Pharmaceutics.

Mechanistic Prediction of First-in-Human Dose for Bispecific CD3/EpCAM T-cell engager Antibody M701, using an Integrated PK/PD Modeling Method.

Dongyang Liu, Ling Song, T. Zhou, 2020, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Pharmacokinetics Analysis Based on Target-Mediated Drug Distribution for RC18, a novel BLyS/APRIL fusion protein to treat Systemic Lupus Erythematosus and Rheumatoid Arthritis.

Xia Chen, Dongyang Liu, Ji Jiang, 2021, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

A population pharmacokinetic study to accelerate early phase clinical development for a novel drug, teriflunomide sodium, to treat systemic lupus erythematosus.

Xia Chen, Dongyang Liu, Ji Jiang, 2019, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Pharmacokinetic and Pharmacodynamic Modeling Analysis of Intravenous Esomeprazole in Healthy Volunteers

Dongyang Liu, Ji Jiang, P. Hu, 2016, Journal of clinical pharmacology.

Development of a simple HPLC-MS/MS method to simultaneously determine teriflunomide and its metabolite in human plasma and urine: Application to clinical pharmacokinetic study of teriflunomide sodium and leflunomide.

Dongyang Liu, Ling Song, Yang Liu, 2019, Biomedical chromatography : BMC.

A model‐based meta analysis study of sodium glucose co‐transporter‐2 inhibitors

Dongyang Liu, Ling Song, P. Hu, 2023, CPT: pharmacometrics & systems pharmacology.

Safety, tolerability, pharmacokinetics, and pharmacodynamics of the glucokinase activator PB-201 and its effects on the glucose excursion profile in drug-naïve Chinese patients with type 2 diabetes: a randomised controlled, crossover, single-centre phase 1 trial

L. Ji, Dongyang Liu, Xueting Yao, 2021, EClinicalMedicine.

Simultaneous quantitative determination of olmesartan and hydrochlorothiazide in human plasma and urine by liquid chromatography coupled to tandem mass spectrometry.

Dongyang Liu, Ji Jiang, P. Hu, 2010, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

A Model-Informed Approach to Accelerate the Clinical Development of Janagliflozin, an Innovative SGLT2 Inhibitor

Dongyang Liu, Ling Song, P. Hu, 2023, Clinical Pharmacokinetics.

Evaluation of the efficacy and safety of hydroxychloroquine in comparison with chloroquine in moderate and severe patients with COVID-19

Jianping Dong, Yahong Chen, J. Qiao, 2021, Science China. Life sciences.

A method for quantification of human transporter proteins by liquid chromatography–tandem mass spectrometry

Dongyang Liu, Guangqin Zhang, Lei Zhang, 2023, SEPARATION SCIENCE PLUS.

Quantitative prediction of human pharmacokinetics and pharmacodynamics of imigliptin, a novel DPP-4 inhibitor, using allometric scaling, IVIVE and PK/PD modeling methods.

Dongyang Liu, Yang Liu, Ji Jiang, 2016, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Translational Modeling and Simulation in Supporting Early-Phase Clinical Development of New Drug: A Learn–Research–Confirm Process

Pei Hu, Yi Zhang, Ji Jiang, 2017, Clinical Pharmacokinetics.

A simple LC-MS/MS method for the simultaneous quantification of drug metabolic enzymes.

Dongyang Liu, Ling Song, Hui Li, 2022, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Simultaneous Determination of Ebastine and Its Active Metabolite (Carebastine) in Human Plasma Using LC–MS–MS

Dongyang Liu, Ji Jiang, P. Hu, 2009 .

Development of a PBPK model to quantitatively understand absorption and disposition mechanism and support future clinical trials for PB‐201

Dongyang Liu, Xueting Yao, Miao Zhang, 2023, CPT: pharmacometrics & systems pharmacology.

Dongyang Liu, Xueting Yao, Miao Zhang, .

PEGylated exenatide injection (PB-119) improves beta-cell function and insulin resistance in treatment-naïve type 2 diabetes mellitus patients

Dongyang Liu, Ling Song, Cheng Cui, 2023, Frontiers in pharmacology.

Potential drug-drug interaction of olverembatinib (HQP1351) using physiologically based pharmacokinetic models

Yangyu Zhao, Y. Zhai, Dongyang Liu, 2022, Frontiers in Pharmacology.

Effect of the CYP2C19 genotype on the pharmacokinetics of icotinib in healthy male volunteers

Dongyang Liu, Ji Jiang, P. Hu, 2012, European Journal of Clinical Pharmacology.

Pharmacokinetic and safety profile of olmesartan medoxomil in healthy Chinese subjects after single and multiple administrations.

Dongyang Liu, Ji Jiang, P. Hu, 2009, Die Pharmazie.

A physiologically based toxicokinetic model of P-glycoprotein transporter-mediated placenta perfusion of dexamethasone in the pregnant rat.

Dongyang Liu, Xiaoqi Zhao, Ling Song, 2023, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Simultaneous determination of imigliptin and its three metabolites in human plasma and urine by liquid chromatography coupled to tandem mass spectrometry.

Dongyang Liu, Hanlin Song, Yang Liu, 2015, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

A single-dose study investigating the pharmacokinetics and pharmacodynamics of edoxaban at 30–90 mg in healthy Chinese volunteers

Xia Chen, Dongyang Liu, Hanlin Song, 2017, Xenobiotica; the fate of foreign compounds in biological systems.