P. Hu

发表

A unified strategy in selection of the best allometric scaling methods to predict human clearance based on drug disposition pathway

Dongyang Liu, Hanlin Song, Ling Song, 2016, Xenobiotica; the fate of foreign compounds in biological systems.

Relative contributions of the major human CYP450 to the metabolism of icotinib and its implication in prediction of drug–drug interaction between icotinib and CYP3A4 inhibitors/inducers using physiologically based pharmacokinetic modeling

Dongyang Liu, Ji Jiang, P. Hu, 2015, Expert opinion on drug metabolism & toxicology.

Combining ‘Bottom-Up’ and ‘Top-Down’ Methods to Assess Ethnic Difference in Clearance: Bitopertin as an Example

P. Hu, N. Parrott, M. Martin-Facklam, 2015, Clinical Pharmacokinetics.

Pharmacokinetics, pharmacodynamics, and safety of esomeprazole injection/infusion in healthy Chinese volunteers: A five‐way crossover study

J. Qian, Jingnan Li, Ji Jiang, 2013, Journal of gastroenterology and hepatology.

Pharmacokinetics of 8-hour intravenous infusion of NXY-059: a phase I, randomized, double-blind (within dose panels), placebo-controlled study in healthy Chinese volunteers.

Ji Jiang, P. Hu, D. Nilsson, 2008, Clinical therapeutics.

Dipeptidyl-Peptidase-IV Inhibitors, Imigliptin and Alogliptin, Improve Beta-Cell Function in Type 2 Diabetes

Xinhua Xiao, Dongyang Liu, Yang Liu, 2021, Frontiers in Endocrinology.

A UPLC-MS/MS method for quantification of 5α-androst-3β,5,6β-triol in human plasma: development, validation and its application in clinical pharmacokinetic study.

Ji Jiang, P. Hu, Qian Zhao, 2017, Bioanalysis.

First-in-human phase I study of BPI-9016M, a dual MET/Axl inhibitor, in patients with non-small cell lung cancer

Yuankai Shi, X. Hao, P. Hu, 2020, Journal of Hematology & Oncology.

A high‐performance liquid chromatography‐tandem mass spectrometry method for the determination of lifrafenib, a novel RAF kinase and EGFR inhibitor, in human plasma and urine and its application in clinical pharmacokinetic study

Dongyang Liu, Ling Song, Yang Liu, 2019, Journal of pharmaceutical and biomedical analysis.

Reduced Effectiveness and Comparable Safety in Biweekly vs. Weekly PEGylated Recombinant Human Growth Hormone for Children With Growth Hormone Deficiency: A Phase IV Non-Inferiority Threshold Targeted Trial

P. Hu, Qian Zhao, Chengjun Sun, 2021, Frontiers in Endocrinology.

Development of a Physiologically Based Pharmacokinetic Model for Sinogliatin, a First-in-Class Glucokinase Activator, by Integrating Allometric Scaling, In Vitro to In Vivo Exploration and Steady-State Concentration–Mean Residence Time Methods: Mechanistic Understanding of its Pharmacokinetics

Dongyang Liu, Ling Song, Ji Jiang, 2018, Clinical Pharmacokinetics.

Pharmacokinetics, Pharmacodynamics and Preliminary Observations for Clinical Activity and Safety of Multiple Doses of Human Mouse Chimeric Anti-CD22 Monoclonal Antibody (SM03) in Chinese Patients with Systemic Lupus Erythematosus

Xia Chen, Ji Jiang, P. Hu, 2016, Clinical Drug Investigation.

Liquid chromatography-tandem mass spectrometry methods for quantification of roxadustat (FG-4592) in human plasma and urine and the applications in two clinical pharmacokinetic studies.

Xia Chen, Ji Jiang, P. Hu, 2022, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Pharmacokinetic and Pharmacodynamic Profiles of a Fixed-Dose Combination of Olmesartan Medoxomil and Amlodipine in Healthy Chinese Males and Females

Tao Liu, Xia Chen, Ji Jiang, 2012, Clinical Drug Investigation.

Translational Prediction of first-in-human Pharmacokinetics and Pharmacodynamics of janagliflozin, a selective SGLT2 inhibitor, using Allometric Scaling, Dedrick and PK/PD Modeling Methods.

Dongyang Liu, Ling Song, Yang Liu, 2020, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Development of an HPLC-MS/MS method to determine janagliflozin in human plasma and urine: application in clinical study.

Dongyang Liu, Ling Song, Yang Liu, 2018, Bioanalysis.

Pharmacokinetics, Pharmacodynamics, and Tolerability of Single Ascending Doses of RCT-18 in Chinese Patients with Rheumatoid Arthritis

Xia Chen, Ji Jiang, P. Hu, 2014, Clinical Pharmacokinetics.

Safety, Pharmacokinetics, and Pharmacogenetics of Single-Dose Teriflunomide Sodium and Leflunomide in Healthy Chinese Subjects

Xia Chen, Dongyang Liu, Ji Jiang, 2019, Clinical Drug Investigation.

Pharmacokinetic and Pharmacodynamic Properties of Cinacalcet (KRN1493) in Chinese Healthy Volunteers: A Randomized, Open-label, Single Ascending-dose and Multiple-dose, Parallel-group Study.

F. Gao, Tao Liu, Xia Chen, 2016, Clinical therapeutics.

Preserved pharmacokinetics and pharmacodynamics of insulin degludec and liraglutide when administered as insulin degludec/liraglutide in a Chinese population

Xia Chen, S. Ingwersen, P. Hu, 2021, Journal of diabetes investigation.

Pharmacokinetics of single- and multiple-dose roflumilast: an open-label, three-way crossover study in healthy Chinese volunteers

P. Hu, Chengxian Guo, Chengxiao Fu, 2018, Drug design, development and therapy.

Effects of four traditional Chinese medicines on the pharmacokinetics of simvastatin

Ji Jiang, P. Hu, Qian Zhao, 2015, Xenobiotica; the fate of foreign compounds in biological systems.

Safety, pharmacokinetics, and efficacy of BPI-15086 in patients with EGFR T790M-mutated advanced non-small-cell lung cancer: results from a phase I, single-arm, multicenter study

P. Xing, P. Hu, X. Chen, 2022, ESMO open.

Clinical pharmacokinetics, safety, and preliminary efficacy evaluation of icotinib in patients with advanced non-small cell lung cancer.

Dongyang Liu, Ji Jiang, P. Hu, 2015, Lung cancer.

Cerebrospinal fluid concentrations of gefitinib in patients with lung adenocarcinoma.

Jing Zhao, Li Zhang, Yi Xiao, 2013, Clinical lung cancer.

Therapeutic effects and adverse drug reactions are affected by icotinib exposure and CYP2C19 and EGFR genotypes in Chinese non-small cell lung cancer patients.

Dongyang Liu, Ji Jiang, P. Hu, 2014, Asian Pacific journal of cancer prevention : APJCP.

Determination of phenylephrine in human plasma using ultra-performance liquid chromatography-tandem mass spectrometry.

Ji Jiang, P. Hu, Qian Zhao, 2013, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

A Novel Third-generation EGFR Tyrosine Kinase Inhibitor Abivertinib for EGFR T790M-mutant Non–Small Cell Lung Cancer: a Multicenter Phase I/II Study

Ying Cheng, Yi-long Wu, B. Han, 2021, Clinical cancer research : an official journal of the American Association for Cancer Research.

A high-performance liquid chromatography-tandem mass spectrometry method for simultaneous determination of imigliptin, its five metabolites and alogliptin in human plasma and urine and its application to a multiple-dose pharmacokinetic study.

Dongyang Liu, Ling Song, Yang Liu, 2018, Biomedical chromatography : BMC.

Measurement of 1- and 3-methylhistidine in human urine by ultra performance liquid chromatography-tandem mass spectrometry.

Ji Jiang, P. Hu, Hongyun Wang, 2012, Clinica chimica acta; international journal of clinical chemistry.

Rapid Determination of Underivatized Arginine, Ornithine, Citrulline and Symmetric/Asymmetric Dimethylarginine in Human Plasma by LC–MS

Ji Jiang, P. Hu, Hongyun Wang, 2010 .

The Pharmacokinetics, Pharmacodynamics, and Tolerability of Liraglutide, a Once‐Daily Human GLP‐1 Analogue, After Multiple Subcutaneous Administration in Healthy Chinese Male Subjects

Ji Jiang, P. Hu, L. Jacobsen, 2011, Journal of clinical pharmacology.

Pharmacokinetics and Pharmacodynamics of Vildagliptin in Healthy Chinese Volunteers

Yan-Ling He, Dongyang Liu, Ji Jiang, 2009, Journal of clinical pharmacology.

Metabolites characterization of a novel DPP‐4 inhibitor, imigliptin in humans and rats using ultra‐high performance liquid chromatography coupled with synapt high‐resolution mass spectrometry

Dongyang Liu, Ling Song, Yang Liu, 2018, Journal of pharmaceutical and biomedical analysis.

[Interaction of butylphthalide with rat and human liver CYP450 isoenzymes].

Ji Jiang, P. Hu, Yan Li, 2015, Yao xue xue bao = Acta pharmaceutica Sinica.

A single and multiple dose study to investigate the pharmacokinetics of a prolonged release formulation of ropinirole in healthy Chinese subjects

Tao Liu, Xia Chen, Ji Jiang, 2014, Clinical pharmacology in drug development.

Pharmacokinetics of Rasagiline in Healthy Adult Chinese Volunteers with Various Genotypes: A Single-Center, Open-Label, Multiple-Dose Study

Xia Chen, Ji Jiang, P. Hu, 2016, Clinical Drug Investigation.

Pharmacokinetics of LBPT and its primary metabolites, as well as tolerability in the first‐in‐human study

Ji Jiang, P. Hu, Ming Liu, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Metabolite characterization of a novel anti-cancer agent, icotinib, in humans through liquid chromatography/quadrupole time-of-flight tandem mass spectrometry.

Dongyang Liu, Ji Jiang, P. Hu, 2011, Rapid communications in mass spectrometry : RCM.

Pharmacodynamics and Pharmacokinetics of Fluticasone Furoate/Vilanterol in Healthy Chinese Subjects

Xia Chen, Ji Jiang, P. Hu, 2015, Pharmacotherapy.

Simultaneous determination of a novel antifibrotic agent and three metabolites in human urine by LC-MS/MS.

Ji Jiang, P. Hu, Ao Peng, 2010, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Application of a physiologically based pharmacokinetic model for the evaluation of single-point plasma phenotyping method of CYP2D6.

P. Hu, A. Rostami-Hodjegan, Jun Shi, 2016, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Evaluating a physiologically based pharmacokinetic model for prediction of omeprazole clearance and assessing ethnic sensitivity in CYP2C19 metabolic pathway

P. Hu, N. Parrott, O. Yin, 2015, European Journal of Clinical Pharmacology.

Pharmacokinetics, pharmacodynamics, short term efficacy and safety of RCT-18, a novel BLyS/APRIL fusion protein, in patients with rheumatoid arthritis.

Xia Chen, Ji Jiang, P. Hu, 2016, British journal of clinical pharmacology.

A Phase I study to evaluate the pharmacokinetics of axitinib (AG-13736) in healthy Chinese volunteers.

P. Hu, Y. Pithavala, M. Tortorici, 2011, International journal of clinical pharmacology and therapeutics.

First-In-Human Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of SHR2285, a Small-Molecule Factor XIa Inhibitor in Healthy Subjects

Shuyang Zhang, P. Hu, J. Zou, 2022, Frontiers in Pharmacology.

Simultaneous determination of roflumilast and its metabolite in human plasma by LC-MS/MS: Application for a pharmacokinetic study.

Ji Jiang, P. Hu, Jie Huang, 2016, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Pharmacokinetic analysis of gefitinib in a patient with advanced non‐small cell lung cancer undergoing hemodialysis

K. Zheng, Yi Xiao, P. Hu, 2015, Thoracic Cancer.

Use of Stable Calcium Isotopes (42Ca & 44Ca) in Evaluation of Calcium Absorption in Beijing Adolescents with Low Vitamin D Status

J. Cheng, Ji Jiang, P. Hu, 2002, Food and nutrition bulletin.

Calcium Absorption Measured by Stable Calcium Isotopes (42Ca & 44Ca) among Northern Chinese Adolescents with Low Vitamin D Status

Jack C. Y. Cheng, Ji Jiang, P. Hu, 2002, Journal of orthopaedic surgery.

Pharmacokinetic and Pharmacodynamic Properties of Cinacalcet ( KRN 1493 ) in Chinese Healthy Volunteers : A Randomized , Open-label , Single Ascending – dose and Multiple-dose , Parallel-group Study

Tao Liu, Xia Chen, F. Gao, 2016 .

Determination of a PDE4 inhibitor Hemay005 in human plasma and urine by UPLC-MS/MS and its application to a PK study.

Ji Jiang, P. Hu, Hongyun Wang, 2018, Bioanalysis.

UHPLC-MS/MS method to determine FP-208 in human plasma and its application to a pharmacokinetic study.

Ji Jiang, P. Hu, Qian Zhao, 2020, Bioanalysis.

Nilotinib for imatinib-resistant or -intolerant chronic myeloid leukemia in chronic phase, accelerated phase, or blast crisis: a single- and multiple-dose, open-label pharmacokinetic study in Chinese patients.

Jianxiang Wang, P. Hu, O. Yin, 2009, Clinical therapeutics.

Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphoma

Ji Jiang, P. Hu, Fen Yang, 2018, Front. Pharmacol..

Determination of free and total vincristine in human plasma after intravenous administration of vincristine sulfate liposome injection using ultra-high performance liquid chromatography tandem mass spectrometry.

Ji Jiang, P. Hu, Fen Yang, 2013, Journal of chromatography. A.

Population Pharmacokinetic Analysis of Yimitasvir in Chinese Healthy Volunteers and Patients With Chronic Hepatitis C Virus Infection

Dan Wu, P. Hu, Hongming Xie, 2020, Frontiers in Pharmacology.

Pharmacokinetics, Pharmacodynamics, and Safety of Single-Dose Canagliflozin in Healthy Chinese Subjects.

Xia Chen, P. Hu, S. Weiner, 2015, Clinical therapeutics.

The impact of CYP2D6*41 on CYP2D6 enzyme activity using phenotyping methods in urine, plasma, and saliva

Shuyang Zhang, P. Hu, Xin Zheng, 2022, Frontiers in Pharmacology.

Metoclopramide as pharmacological tool to assess vasopressinergic co-activation of the hypothalamus–pituitary–adrenal (HPA) axis: A study in healthy volunteers

F. Zitman, P. Hu, J. V. Gerven, 2010, European Neuropsychopharmacology.

Pharmacokinetics and safety of subcutaneous pasireotide and intramuscular pasireotide long-acting release in Chinese male healthy volunteers: a phase I, single-center, open-label, randomized study.

Xia Chen, Ji Jiang, P. Hu, 2014, Clinical therapeutics.

Conteltinib (CT-707) in patients with advanced ALK-positive non-small cell lung cancer: a multicenter, open-label, first-in-human phase 1 study

Li Zhang, P. Xing, P. Hu, 2022, BMC Medicine.

Non-Compartmental Pharmacokinetics and Safety of Single-Dose Eldecalcitol (ED-71) in Healthy Chinese Adult Males

Ji Jiang, P. Hu, Qian Zhao, 2018, Clinical Drug Investigation.

Odanacatib Pharmacokinetics Comparison Between Chinese and Non‐Chinese Postmenopausal Women

Xia Chen, Ji Jiang, P. Hu, 2018, Clinical pharmacology in drug development.

Simultaneous determination of remimazolam and its carboxylic acid metabolite in human plasma using ultra-performance liquid chromatography-tandem mass spectrometry.

Ji Jiang, P. Hu, Ying Zhou, 2015, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

A high-performance liquid chromatography-tandem mass spectrometry method coupled with protein precipitation for determination of granisetron in human plasma and its application to a comparative pharmacokinetic study.

Ji Jiang, P. Hu, Ying Zhou, 2014, Biomedical chromatography : BMC.

Determination of LBPT in human plasma by high performance liquid chromatography-tandem mass spectrometry.

Ji Jiang, P. Hu, Fen Yang, 2014, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Determination of pseudo-ginsenoside GQ in human plasma by high performance liquid chromatography-tandem mass spectrometry.

Ji Jiang, P. Hu, Jinping Liu, 2013, Biomedical chromatography : BMC.

Simultaneous determination of blonanserin and its four metabolites in human plasma using ultra-performance liquid chromatography-tandem mass spectrometry.

Ji Jiang, P. Hu, Ying Zhou, 2013, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

LC–MS–MS Quantitative Determination of Gefitinib in Human Serum and Cerebrospinal Fluid

Ji Jiang, P. Hu, W. Zhong, 2011 .

Determination of higenamine in human plasma and urine using liquid chromatography coupled to positive electrospray ionization tandem mass spectrometry.

Ji Jiang, P. Hu, Sheng Feng, 2011, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Measurement of endogenous uracil and dihydrouracil in plasma and urine of normal subjects by liquid chromatography-tandem mass spectrometry.

Hao Jiang, Ji Jiang, P. Hu, 2002, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Phase I pharmacokinetic study of an oral, small-molecule MEK inhibitor tunlametinib in patients with advanced NRAS mutant melanoma

P. Hu, Qian Zhao, Ying Cheng, 2022, Frontiers in Pharmacology.

Simultaneous determination of olmesartan and amlodipine in human plasma and urine by ultra performance liquid chromatography tandem mass spectrometry.

Ji Jiang, P. Hu, Qian Zhao, 2013, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

An Open-label, Single-dose, Pharmacokinetic Study of Factor VIII Activity After Administration of Moroctocog Alfa (AF-CC) in Male Chinese Patients With Hemophilia A.

P. Hu, S. Nepal, Yali Liang, 2017, Clinical therapeutics.

Validation and Application of an LC-MS-MS Method for the Determination of Ceftizoxime in Human Serum and Urine.

Ji Jiang, P. Hu, Jia Chen, 2016, Journal of chromatographic science.

Pharmacokinetics, Pharmacodynamics and Safety of Multiple-Infusion Ilaprazole in Healthy Chinese Subjects

Ji Jiang, P. Hu, L. Lang, 2016, Clinical Drug Investigation.

Quantitative determination of olmesartan in human plasma and urine by liquid chromatography coupled to tandem mass spectrometry.

Dongyang Liu, Ji Jiang, P. Hu, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Single‐Dose and Multiple‐Dose Pharmacokinetics and Safety of Telbivudine After Oral Administration in Healthy Chinese Subjects

Ji Jiang, P. Hu, N. Brown, 2006, Journal of clinical pharmacology.

Pharmacokinetics and tolerability of olmesartan medoxomil plus hydrochlorothiazide combination in healthy Chinese subjects: drug-drug interaction, bioequivalence, and accumulation.

Ji Jiang, P. Hu, Jian-yan Zhang, 2014, International journal of clinical pharmacology and therapeutics.

Quantitative determination of atorvastatin and para-hydroxy atorvastatin in human plasma by LC-MS-MS.

Dongyang Liu, Ji Jiang, P. Hu, 2008, Journal of chromatographic science.

Pharmacokinetics and pharmacodynamics of intravenous ilaprazole in healthy subjects after single ascending doses

Ji Jiang, P. Hu, L. Lang, 2016, Xenobiotica; the fate of foreign compounds in biological systems.

The pharmacokinetics of lamivudine in healthy Chinese subjects.

P. Hu, A. Harker, J. Jiang, 1999, British journal of clinical pharmacology.

Quantitative determination of icotinib in human plasma and urine using liquid chromatography coupled to tandem mass spectrometry.

Dongyang Liu, Ji Jiang, P. Hu, 2009, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Metabolite characterization of a novel sedative drug, remimazolam in human plasma and urine using ultra high‐performance liquid chromatography coupled with synapt high‐definition mass spectrometry

Ji Jiang, P. Hu, Ying Zhou, 2017, Journal of pharmaceutical and biomedical analysis.

Simultaneous determination of TPN729 and its five metabolites in human plasma and urine by liquid chromatography coupled to tandem mass spectrometry

Dongyang Liu, Hanlin Song, Ling Song, 2018, Journal of pharmaceutical and biomedical analysis.

Simultaneous determination of imigliptin and its three metabolites in human plasma and urine by liquid chromatography coupled to tandem mass spectrometry.

Dongyang Liu, Hanlin Song, Yang Liu, 2015, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Development of population pharmacokinetics model of icotinib with non-linear absorption characters in healthy Chinese volunteers to assess the CYP2C19 polymorphism and food-intake effect

Dongyang Liu, Ji Jiang, P. Hu, 2015, European Journal of Clinical Pharmacology.

Clinical pharmacokinetics of Icotinib, an anti-cancer drug: evaluation of dose proportionality, food effect, and tolerability in healthy subjects

Dongyang Liu, Ji Jiang, P. Hu, 2014, Cancer Chemotherapy and Pharmacology.

Effect of the CYP2C19 genotype on the pharmacokinetics of icotinib in healthy male volunteers

Dongyang Liu, Ji Jiang, P. Hu, 2012, European Journal of Clinical Pharmacology.

Important Role of the Dihydrouracil/Uracil Ratio in Marked Interpatient Variations of Fluoropyrimidine Pharmacokinetics and Pharmacodynamics

Hao Jiang, Ji Jiang, P. Hu, 2004, Journal of clinical pharmacology.

First‐in‐Human Phase I Study of AC0010, a Mutant‐Selective EGFR Inhibitor in Non–Small Cell Lung Cancer: Safety, Efficacy, and Potential Mechanism of Resistance

Yang Zhang, Ji Jiang, P. Hu, 2018, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

An LC–MS/MS method for quantification of AC0010, a novel mutant‐selective epidermal growth factor receptor (EGFR) inhibitor, and its metabolites in human plasma and the application to a pharmacokinetic study

Ji Jiang, P. Hu, Xin Zheng, 2017, Journal of pharmaceutical and biomedical analysis.

Validation of an UPLC-MS-MS Method for Quantitative Analysis of Vincristine in Human Urine After Intravenous Administration of Vincristine Sulfate Liposome Injection.

Ji Jiang, P. Hu, Fen Yang, 2015, Journal of chromatographic science.

Population Pharmacokinetic/Pharmacodynamic Model-Guided Dosing Optimization of a Novel Sedative HR7056 in Chinese Healthy Subjects

Yuguang Huang, Xia Chen, Ji Jiang, 2018, Front. Pharmacol..

Psychomotor Recovery Following Remimazolam-Induced Sedation and the Effectiveness of Flumazenil as an Antidote.

Yuguang Huang, Xia Chen, Ji Jiang, 2020, Clinical therapeutics.

Evaluating a physiologically based pharmacokinetic model for predicting the pharmacokinetics of midazolam in Chinese after oral administration

Pei Hu, Jun Shi, Ji Jiang, 2015, Acta Pharmacologica Sinica.

An UPLC–MS/MS method to determine CT‐707 and its two metabolites in plasma of ALK‐positive advanced non‐small cell lung cancer patients

Ji Jiang, P. Hu, Qian Zhao, 2018, Journal of pharmaceutical and biomedical analysis.

Determination of BPI15086 and its metabolite in human plasma by ultra-high performance liquid chromatography-MS/MS and its application to a pharmacokinetic study.

Ji Jiang, P. Hu, Xin Zheng, 2019, Bioanalysis.

Phase 1 study to investigate the pharmacokinetic properties of dacomitinib in healthy adult Chinese subjects genotyped for CYP2D6

Xia Chen, Ji Jiang, P. Hu, 2018, Xenobiotica; the fate of foreign compounds in biological systems.

Pharmacokinetics of Single Ascending Doses and Multiple Doses of 20(S)-Ginsenoside Rg3 in Chinese Healthy Volunteers

Ji Jiang, P. Hu, Qian Zhao, 2016, European Journal of Drug Metabolism and Pharmacokinetics.

AC0010, an Irreversible EGFR Inhibitor Selectively Targeting Mutated EGFR and Overcoming T790M-Induced Resistance in Animal Models and Lung Cancer Patients

Xiaoying Zhang, Xiao Xu, Ji Jiang, 2016, Molecular Cancer Therapeutics.

AC0010,an IrreversibleEGFRInhibitorSelectively Targeting Mutated EGFR and Overcoming T790M-Induced Resistance in Animal Models and Lung Cancer Patients

Xiaoying Zhang, Wei Tang, Xiao Xu, 2016 .

Penetration of the blood-brain barrier by avitinib and its control of intra/extra-cranial disease in non-small cell lung cancer harboring the T790M mutation.

Li Zhang, P. Hu, Mengzhao Wang, 2018, Lung cancer.

Simultaneous determination of morphine-6-d-glucuronide, morphine-3-d-glucuronide and morphine in human plasma and urine by ultra-performance liquid chromatography-tandem mass spectrometry: Application to M6G injection pharmacokinetic study.

Xia Chen, Ji Jiang, P. Hu, 2018, Biomedical chromatography : BMC.

A validated UPLC–MS/MS method for the quantitation of an unstable peptide, monocyte locomotion inhibitory factor (MLIF) in human plasma and its application to a pharmacokinetic study

Ji Jiang, P. Hu, Hongyun Wang, 2018, Journal of pharmaceutical and biomedical analysis.

Quantitative determination of trimebutine maleate and its three metabolites in human plasma by liquid chromatography-tandem mass spectrometry.

Ji Jiang, P. Hu, T. Mayumi, 2002, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Efficacy and safety of lanreotide autogel compared with lanreotide 40 mg prolonged release in Chinese patients with active acromegaly: results from a phase 3, prospective, randomized, and open-label study (LANTERN)

Ming Zhu, P. Hu, X. Chen, 2020, BMC Endocrine Disorders.

Pharmacokinetics Analysis Based on Target-Mediated Drug Distribution for RC18, a novel BLyS/APRIL fusion protein to treat Systemic Lupus Erythematosus and Rheumatoid Arthritis.

Xia Chen, Dongyang Liu, Ji Jiang, 2021, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

A population pharmacokinetic study to accelerate early phase clinical development for a novel drug, teriflunomide sodium, to treat systemic lupus erythematosus.

Xia Chen, Dongyang Liu, Ji Jiang, 2019, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Pharmacokinetic and Pharmacodynamic Modeling Analysis of Intravenous Esomeprazole in Healthy Volunteers

Dongyang Liu, Ji Jiang, P. Hu, 2016, Journal of clinical pharmacology.

First-in-human phase I dose-escalation and dose-expansion trial of the selective MEK inhibitor HL-085 in patients with advanced melanoma harboring NRAS mutations

P. Hu, Qian Zhao, D. Ji, 2023, BMC Medicine.

CYP2D6 Phenotyping Using Urine, Plasma, and Saliva Metabolic Ratios to Assess the Impact of CYP2D6∗10 on Interindividual Variation in a Chinese Population

P. Hu, Xin Zheng, Rui Chen, 2017, Front. Pharmacol..

Population Pharmacokinetic/Pharmacodynamic Analysis of PEG-rhGH Enhances Confidence in Exploring Dosing Schemes with Longer Intervals.

P. Hu, Qian Zhao, G. Zhong, 2022, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Development of a simple HPLC-MS/MS method to simultaneously determine teriflunomide and its metabolite in human plasma and urine: Application to clinical pharmacokinetic study of teriflunomide sodium and leflunomide.

Dongyang Liu, Ling Song, Yang Liu, 2019, Biomedical chromatography : BMC.

Fixed dosing of kukoamine B in sepsis patients: Results from population pharmacokinetic modelling and simulation

Bin Du, Ji Jiang, P. Hu, 2022, British journal of clinical pharmacology.

Exposure-Response Modeling to Support Dosing Selection for Phase IIb Development of Kukoamine B in Sepsis Patients

Ji Jiang, P. Hu, B. Du, 2021, Frontiers in Pharmacology.

Development and validation of a rapid and sensitive UPLC–MS/MS method for quantification of kukoamine B in human plasma: Application to a clinical pharmacokinetic study

Ji Jiang, P. Hu, Qian Zhao, 2017, Journal of pharmaceutical and biomedical analysis.

An ultra HPLC-MS/MS method for quantification of hypidone hydrochloride (YL-0919) and application to a pharmacokinetic study.

Ji Jiang, P. Hu, Qian Zhao, 2019, Bioanalysis.

A model‐based meta analysis study of sodium glucose co‐transporter‐2 inhibitors

Dongyang Liu, Ling Song, P. Hu, 2023, CPT: pharmacometrics & systems pharmacology.

A phase I study on pharmacokinetics and pharmacodynamics of higenamine in healthy Chinese subjects

Tao Liu, Ji Jiang, P. Hu, 2012, Acta Pharmacologica Sinica.

Evaluating a physiologically based pharmacokinetic model for prediction of omeprazole clearance and assessing ethnic sensitivity in CYP2C19 metabolic pathway

P. Hu, N. Parrott, O. Yin, 2015, European Journal of Clinical Pharmacology.

Pharmacokinetics and Safety of Tedizolid after Single and Multiple Intravenous/Oral Sequential Administrations in Healthy Chinese Subjects.

P. Hu, Kai Shen, Toshiaki Tanaka, 2016, Clinical therapeutics.

Safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of WBP216, a novel IL-6 monoclonal antibody, in patients with rheumatoid arthritis: A phase Ia randomized placebo-controlled study

P. Hu, X. Leng, Xiao-duo Guan, 2023, Frontiers in Immunology.

Modeling and Simulation to Support Phase Ib/IIa Dose Selection for WBP216, A Long Half-Life Fully Human Monoclonal Antibody Against Interleukin-6

P. Hu, Xiaofeng Zeng, Xiao-duo Guan, 2021, Frontiers in Pharmacology.

Calcium bioavailability of calcium L-threonate in healthy Chinese subjects measured with stable isotopes (44Ca and 42Ca)

Ji Jiang, P. Hu, Hongyun Wang, 2013, European Journal of Clinical Pharmacology.

Simultaneous quantitative determination of olmesartan and hydrochlorothiazide in human plasma and urine by liquid chromatography coupled to tandem mass spectrometry.

Dongyang Liu, Ji Jiang, P. Hu, 2010, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

A phase 1 pharmacokinetic study of oral NEPA, the fixed combination of netupitant and palonosetron, in Chinese healthy volunteers

P. Hu, A. Bernareggi, S. Chessari, 2021, Cancer Chemotherapy and Pharmacology.

Pharmacokinetics and safety evaluation of oral Palonosetron in Chinese healthy volunteers: A phase 1, open-label, randomized, cross-over study.

P. Hu, A. Bernareggi, S. Chessari, 2021, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Development and validation of a UPLC-MS/MS method for simultaneous determination of fotagliptin and its two major metabolites in human plasma and urine.

Ji Jiang, P. Hu, Qian Zhao, 2017, Bioanalysis.

A Model-Informed Approach to Accelerate the Clinical Development of Janagliflozin, an Innovative SGLT2 Inhibitor

Dongyang Liu, Ling Song, P. Hu, 2023, Clinical Pharmacokinetics.

Determination of idebenone in plasma by HPLC/MS.

P. Hu, H. Xie, J. Jiang, 2000, Acta Pharmacologica Sinica.

Determination of ginsenoside Rg3 in human plasma and urine by high performance liquid chromatography-tandem mass spectrometry.

Ji Jiang, P. Hu, Xin Zheng, 2010, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Development and validation of a UPLC-MS/MS method for quantification of osimertinib (AZD9291) and its metabolite AZ5104 in human plasma.

Ji Jiang, P. Hu, Yu-xiang Ma, 2018, Biomedical chromatography : BMC.

Determination of nicousamide in human plasma by liquid chromatography-tandem mass spectrometry.

Ji Jiang, P. Hu, Qian Zhao, 2013, Journal of pharmaceutical and biomedical analysis.

Pharmacokinetics, Pharmacodynamics, Safety, and Clinical Activity of Multiple Doses of RCT‐18 in Chinese Patients With Systemic Lupus Erythematosus

Xia Chen, Ji Jiang, P. Hu, 2016, Journal of clinical pharmacology.

Pharmacokinetic characteristics of golidocitinib, a highly selective JAK1 inhibitor, in healthy adult participants

P. Hu, Ziyi Liu, Kan Chen, 2023, Frontiers in Immunology.

Cytochrome P450 2D6 genotype affects the pharmacokinetics of controlled-release paroxetine in healthy Chinese subjects: comparison of traditional phenotype and activity score systems

P. Hu, Jun Shi, Kai Shen, 2015, European Journal of Clinical Pharmacology.

Determination of L-threonate in human plasma and urine by high performance liquid chromatography-tandem mass spectrometry.

Ji Jiang, P. Hu, Hongyun Wang, 2006, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Development of an LC-MS/MS method for quantifying two main metabolites of abivertinib in human plasma.

Ji Jiang, P. Hu, Yu-xiang Ma, 2020, Biomedical chromatography : BMC.

Determination of cinacalcet hydrochloride in human plasma by liquid chromatography-tandem mass spectrometry.

Ji Jiang, P. Hu, Fen Yang, 2012, Journal of pharmaceutical and biomedical analysis.

Quantitative prediction of human pharmacokinetics and pharmacodynamics of imigliptin, a novel DPP-4 inhibitor, using allometric scaling, IVIVE and PK/PD modeling methods.

Dongyang Liu, Yang Liu, Ji Jiang, 2016, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Safety, tolerability, pharmacokinetics, and efficacy of kukoamine B in patients with sepsis: A randomized phase IIa trial.

B. Zang, Yunbo Sun, P. Hu, 2023, Journal of critical care.

Pharmacokinetics, Safety and Tolerability of Single and Multiple Oral Doses of Aliskiren in Healthy Chinese Subjects

Shuyang Zhang, Ji Jiang, P. Hu, 2010, Clinical drug investigation.

Method Transfer, Partial Validation, and Cross Validation: Recommendations for Best Practices and Harmonization from the Global Bioanalysis Consortium Harmonization Team

K. S. Mahesh, P. Hu, F. Vazvaei, 2014, The AAPS Journal.

An UHPLC-MS/MS method to determine FLZ major active metabolites in human plasma: application to a pharmacokinetic study.

Ji Jiang, P. Hu, Qian Zhao, 2020, Bioanalysis.

Simultaneous determination of FLZ and its metabolite (M1) in human plasma and urine by UHPLC‐MS/MS: Application to a pharmacokinetic study

Wei Wang, Ji Jiang, P. Hu, 2019, Journal of pharmaceutical and biomedical analysis.

Pharmacokinetics of vorapaxar and its metabolite following oral administration in healthy Chinese and American subjects.

Xia Chen, Ji Jiang, P. Hu, 2014, International journal of clinical pharmacology and therapeutics.