J. Troutman

发表

Extrapolation of systemic bioavailability assessing skin absorption and epidermal and hepatic metabolism of aromatic amine hair dyes in vitro.

T. Baker, N. Hewitt, J. Manwaring, 2015, Toxicology and applied pharmacology.

Introduction of a methoxymethyl side chain into p-phenylenediamine attenuates its sensitizing potency and reduces the risk of allergy induction.

H. Rothe, J. Troutman, C. Goebel, 2014, Toxicology and applied pharmacology.

Utilization of Peptide Reactivity Assays for the Prediction of Skin Sensitization

J. Troutman, G. Gerberick, L. Foertsch, 2017 .

Refinement of the Peroxidase Peptide Reactivity Assay and Prediction Model for Assessing Skin Sensitization Potential.

J. Troutman, C. Ryan, G. Gerberick, 2020, Toxicological sciences : an official journal of the Society of Toxicology.

Novel Insights into Pyrrolizidine Alkaloid Toxicity and Implications for Risk Assessment: Occurrence, Genotoxicity, Toxicokinetics, Risk Assessment–AWorkshop Report

D. Schrenk, G. Lin, S. Pfuhler, 2021 .

Novel Insights into Pyrrolizidine Alkaloid Toxicity and Implications for Risk Assessment: Occurrence, Genotoxicity, Toxicokinetics, Risk Assessment–A Workshop Report

D. Schrenk, G. Lin, S. Pfuhler, 2021, Planta Medica.

Intrinsic relative potency of a series of pyrrolizidine alkaloids characterized by rate and extent of metabolism.

C. Obringer, J. Troutman, A. Roe, 2019, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Cosmetics Europe evaluation of 6 in silico skin penetration models

E. Fabian, N. Hewitt, J. Troutman, 2021, Computational Toxicology.

Development of a physiologically-based pharmacokinetic model of 2-phenoxyethanol and its metabolite phenoxyacetic acid in rats and humans to address toxicokinetic uncertainty in risk assessment.

Jeffrey Fisher, John A Troutman, Sharon B Stuard, 2015, Regulatory toxicology and pharmacology : RTP.

A framework incorporating the impact of exposure scenarios and application conditions on risk assessment of chemicals applied to skin

J. Jaworska, J. Troutman, Y. Dancik, 2013, In Silico Pharmacology.

The incorporation of lysine into the peroxidase peptide reactivity assay for skin sensitization assessments.

Petra S Kern, G Frank Gerberick, Jean-Pierre Lepoittevin, 2011, Toxicological sciences : an official journal of the Society of Toxicology.

Investigation of peptide reactivity of pro-hapten skin sensitizers using a peroxidase-peroxide oxidation system.

G Frank Gerberick, Jean-Pierre Lepoittevin, Carsten Goebel, 2009, Toxicological sciences : an official journal of the Society of Toxicology.

Use of in vitro metabolism and biokinetics assays to refine predicted in vivo and in vitro internal exposure to the cosmetic ingredient, phenoxyethanol, for use in risk assessment.

N. Hewitt, G. Ouedraogo, J. Troutman, 2022, Regulatory toxicology and pharmacology : RTP.

Reactivity of chemical respiratory allergens in the Peroxidase Peptide Reactivity Assay.

I Kimber, A M Api, G F Gerberick, 2013, Toxicology in vitro : an international journal published in association with BIBRA.

EURL ECVAM WORKSHOP ON NEW GENERATION OF PHYSIOLOGICALLY-BASED KINETIC MODELS IN RISK ASSESSMENT

George Loizou, Judith C. Madden, Eann A. Patterson, 2017 .

Estimation of in vivo dose of dermally applied chemicals leading to estrogen/androgen receptor-mediated toxicity from in vitro data--Illustration with four reproductive toxicants.

Yuri Dancik, Joanna Jaworska, John A Troutman, 2015, Reproductive toxicology.

In vitro to in vivo extrapolation for high throughput prioritization and decision making.

Alicia Paini, Annie Lumen, Judy Strickland, 2018, Toxicology in vitro : an international journal published in association with BIBRA.

Next generation physiologically based kinetic (NG-PBK) models in support of regulatory decision making

A Worth, N Suciu, J C Madden, 2019, Computational toxicology.

Development of growth equations from longitudinal studies of body weight and height in the full term and preterm neonate: From birth to four years postnatal age

J. Fisher, J. Troutman, G. Carr, 2018, Birth defects research.

Predicting the pharmacokinetics of piperacillin and tazobactam in preterm and term neonates using physiologically based pharmacokinetic modeling

J. Fisher, M. Cohen-Wolkowiez, J. Troutman, 2019, Computational Toxicology.

A Mechanistic Bayesian Inferential Workflow for Estimation of In Vivo Skin Permeation From In Vitro Measurements.

J. Troutman, A. Najjar, A. Edginton, 2021, Journal of pharmaceutical sciences.

Effect of chain length and branching on the in vitro metabolism of a series of parabens in human liver S9, human skin S9, and human plasma.

C. Obringer, J. Troutman, Shengde Wu, 2021, Regulatory toxicology and pharmacology : RTP.

Ontogeny equations with probability distributions for anthropomorphic measurements in preterm and term neonates and infants for use in a PBPK model

J. Fisher, J. Troutman, Jian Wang, 2019, Computational Toxicology.

Assessment of Vehicle Volatility and Deposition Layer Thickness in Skin Penetration Models

J. Troutman, A. Edginton, A. Hamadeh, 2021, Pharmaceutics.