D. Trenk

Cornelius Lehane, F. Beyersdorf, D. Trenk, 2011, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

TIME COURSE OF CYCLOSPORIN/ITRACONAZOLE INTERACTION

D. Trenk, D. Birnbaum, E. Jähnchen, 1987, The Lancet.

Pharmacodynamic and Pharmacokinetic Evaluation of a New Transdermal Delivery System with a Time‐Dependent Release of Glyceryl Trinitrate

D. Trenk, A. Wiegand, R. Bonn, 1992, Journal of clinical pharmacology.

Response variability to P2Y12 receptor inhibitors: expectations and reality.

K. Huber, M. Gawaz, K. Schrör, 2013, JACC. Cardiovascular interventions.

Diabetes and Outcomes following Guided De-Escalation of Antiplatelet Treatment in Acute Coronary Syndrome Patients Undergoing Percutaneous Coronary Intervention: A Prespecified Analysis from the Randomized TROPICAL-ACS Trial.

M. Hadamitzky, H. Ince, B. Merkely, 2019, EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology.

Randomized Comparison of Oral P2Y12-Receptor Inhibitor Loading Strategies for Transitioning From Cangrelor: The ExcelsiorLOAD2 Trial.

F. Neumann, M. Amann, D. Trenk, 2017, JACC. Cardiovascular interventions.

Comparison of Immature Platelet Count to Established Predictors of Platelet Reactivity During Thienopyridine Therapy.

F. Neumann, M. Amann, D. Trenk, 2016, Journal of the American College of Cardiology.

Pharmacodynamic safety of clopidogrel monotherapy in patients under oral anticoagulation with a vitamin K antagonist undergoing coronary stent implantation

F. Neumann, D. Trenk, W. Hochholzer, 2018, Platelets.

A randomised trial on platelet function-guided de-escalation of antiplatelet treatment in ACS patients undergoing PCI

M. Hadamitzky, J. Mehilli, F. Neumann, 2016, Thrombosis and Haemostasis.

Randomized Comparison of Different Thienopyridine Loading Strategies in Patients Undergoing Elective Coronary Intervention: The ExcelsiorLOAD Trial.

F. Neumann, M. Amann, D. Trenk, 2016, JACC. Cardiovascular interventions.

Abstract 2126: CYP2C19 Genetic Variants and Clinical Outcomes With Clopidogrel: A Collaborative Meta-Analysis

J. Mega, B. Horne, Jeffrey L. Anderson, 2009 .

Antagonizing P2Y12 Receptor Inhibitors: Current and Future Options

K. Schrör, D. Sibbing, D. Aradi, 2019, Thrombosis and Haemostasis.

Validation of a P2Y12-receptor specific whole blood platelet aggregation assay

F. Neumann, M. Amann, D. Trenk, 2016, Platelets.

Prasugrel Compared With High Loading– and Maintenance–Dose Clopidogrel in Patients With Planned Percutaneous Coronary Intervention: The Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation–Thrombolysis in Myocardial Infarction 44 Trial

E. Antman, E. Braunwald, Richard Cairns, 2007, Circulation.

Clopidogrel pretreatment of patients with ST-elevation myocardial infarction does not affect platelet reactivity after subsequent prasugrel-loading: Platelet reactivity in an observational study

F. Neumann, M. Amann, D. Trenk, 2013, Platelets.

Cilostazol: the "poor man's" replacement of drug-eluting stents and balloons?

D. Trenk, T. Zeller, 2013, Circulation.

37th International Symposium on Intensive Care and Emergency Medicine (part 2 of 3)

G. Auzinger, D. Pavelescu, M. Dickinson, 2017, Critical Care.

Pharmacokinetics of Moxonidine After Single and Repeated Daily Doses in Healthy Volunteers

D. Trenk, F. Wagner, E. Jähnchen, 1987, Journal of clinical pharmacology.

Platelet reactivity and clinical outcomes in acute coronary syndrome patients treated with prasugrel and clopidogrel: a pre-specified exploratory analysis from the TROPICAL-ACS trial.

M. Hadamitzky, F. Neumann, B. Merkely, 2019, European heart journal.

Pharmacodynamic evaluation of switching from ticagrelor to prasugrel in patients with stable coronary artery disease: Results of the SWAP-2 Study (Switching Anti Platelet-2).

M. Effron, N. Curzen, D. Angiolillo, 2014, Journal of the American College of Cardiology.

Consensus and update on the definition of on-treatment platelet reactivity to adenosine diphosphate associated with ischemia and bleeding.

Deepak L. Bhatt, Sunil V. Rao, M. Price, 2013, Journal of the American College of Cardiology.

Guided de-escalation of antiplatelet treatment in patients with acute coronary syndrome undergoing percutaneous coronary intervention (TROPICAL-ACS): a randomised, open-label, multicentre trial

M. Hadamitzky, P. Boekstegers, J. Mehilli, 2017, The Lancet.

Ticagrelor or Prasugrel in Patients With ST-Segment–Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

H. Schunkert, M. Joner, A. Kastrati, 2020, Circulation.

Use of B-type natriuretic peptide to predict blood pressure improvement after percutaneous revascularisation for renal artery stenosis.

A. Jacob, M. Aschwanden, K. Jaeger, 2010, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

Ticagrelor or Prasugrel in Patients With Non-ST-Segment Elevation Acute Coronary Syndromes.

H. Schunkert, M. Joner, A. Kastrati, 2020, Journal of the American College of Cardiology.

Pharmacogenomic Polygenic Response Score Predicts Ischemic Events and Cardiovascular Mortality in Clopidogrel-Treated Patients.

R. Altman, L. Gong, T. Klein, 2019, European heart journal. Cardiovascular pharmacotherapy.

CLINICAL RESEARCH Interventional Cardiology Impact of the Degree of Peri-Interventional Platelet Inhibition After Loading With Clopidogrel on Early Clinical Outcome of Elective Coronary Stent Placement

F. Neumann, D. Trenk, A. Caputo, 2006 .

The impact of platelet count on mortality in unstable angina/non-ST-segment elevation myocardial infarction.

F. Neumann, C. Mueller, D. Trenk, 2006, American heart journal.

Pharmacy‐based interdisciplinary intervention for patients with chronic heart failure: results of the PHARM‐CHF randomized controlled trial

S. Anker, F. Koehler, U. Laufs, 2019, European journal of heart failure.

Age- and Weight-Adapted Dose of Prasugrel Versus Standard Dose of Ticagrelor in Patients With Acute Coronary Syndromes

H. Schunkert, A. Kastrati, F. Neumann, 2020, Annals of Internal Medicine.

Impact of smoking on antiplatelet effect of clopidogrel and prasugrel after loading dose and on maintenance therapy.

J. Mega, M. Sabatine, A. Kastrati, 2011, American heart journal.

Smoking and Outcomes Following Guided De-escalation of Antiplatelet Treatment in Acute Coronary Syndrome Patients: A Substudy from the Randomized TROPICAL-ACS Trial.

M. Hadamitzky, K. Huber, J. Rieber, 2019, European heart journal. Cardiovascular pharmacotherapy.

PON1 Q192R genetic variant and response to clopidogrel and prasugrel: pharmacokinetics, pharmacodynamics, and a meta-analysis of clinical outcomes

E. Antman, J. Mega, M. Price, 2015, Journal of Thrombosis and Thrombolysis.

High on-treatment platelet reactivity and P2Y12 antagonists in clinical trials

F. Neumann, S. Kristensen, D. Trenk, 2012, Thrombosis and Haemostasis.

Paraoxonase-1 Q192R Polymorphism and Antiplatelet Effects of Clopidogrel in Patients Undergoing Elective Coronary Stent Placement

M. Fromm, F. Neumann, D. Trenk, 2011, Circulation. Cardiovascular genetics.

Cytochrome P 450 2 C 19 681 G > A Polymorphism and High On-Clopidogrel Platelet Reactivity Associated With Adverse 1-Year Clinical Outcome of Elective Percutaneous Coronary Intervention With Drug-Eluting or Bare-Metal Stents

M. Fromm, F. Neumann, D. Trenk, 2008 .

Specific Electrogram Characteristics Identify the Extra-Pulmonary Vein Arrhythmogenic Sources of Persistent Atrial Fibrillation – Characterization of the Arrhythmogenic Electrogram Patterns During Atrial Fibrillation and Sinus Rhythm

O. Dössel, F. Neumann, A. Loewe, 2020, Scientific Reports.

Argatroban pharmacokinetics and pharmacodynamics in critically ill cardiac surgical patients with suspected heparin-induced thrombocytopenia

D. Trenk, M. Bek, C. Keyl, 2016, Thrombosis and Haemostasis.

Intrinsic platelet reactivity before start with clopidogrel as predictor for on-clopidogrel platelet function and long-term clinical outcome

F. Neumann, M. Amann, D. Trenk, 2015, Thrombosis and Haemostasis.

International Expert Consensus on Switching Platelet P2Y12 Receptor–Inhibiting Therapies

Deepak L. Bhatt, M. Price, R. Mehran, 2017, Circulation.

Intrinsic platelet reactivity before P2Y12 blockade contributes to residual platelet reactivity despite high-level P2Y12 blockade by prasugrel or high-dose clopidogrel

E. Antman, E. Braunwald, C. McCabe, 2011, Thrombosis and Haemostasis.

Antiplatelet response to the 150-mg maintenance dose of clopidogrel in patients with insufficient platelet inhibition after clopidogrel loading for elective coronary stent placement.

F. Neumann, D. Trenk, W. Hochholzer, 2008, EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology.

Age-dependent differences in the anticoagulant effect of phenprocoumon in patients after heart valve surgery

C. Gohlke-Bärwolf, D. Trenk, H. Roskamm, 1997, European Journal of Clinical Pharmacology.

Transcriptome Analysis in Patients with Progressive Coronary Artery Disease: Identification of Differential Gene Expression in Peripheral Blood

T. Kurz, H. Binder, F. Neumann, 2013, Journal of Cardiovascular Translational Research.

Vericiguat in combination with isosorbide mononitrate in patients with chronic coronary syndromes: The randomized, phase Ib, VISOR study

D. Trenk, G. Mikus, M. Boettcher, 2022, Clinical and translational science.

Differences in the antiischaemic effects of molsidomine and isosorbide dinitrate (ISDN) during acute and short-term administration in stable angina pectoris.

C. Gohlke-Bärwolf, D. Trenk, H. Roskamm, 1991, European heart journal.

Lack of Effect of Enoximone on the Pharmacokinetics of Digoxin in Patients with Congestive Heart Failure

B. Winkelmann, D. Trenk, H. Dieterich, 1990, Journal of clinical pharmacology.

Pharmacodynamics, pharmacokinetics, and safety of single-dose subcutaneous administration of selatogrel, a novel P2Y12 receptor antagonist, in patients with chronic coronary syndromes

G. Dangas, P. van der Harst, V. Kunadian, 2019, European heart journal.

Thrombelastography Compared with Multiple Impedance Aggregometry to Assess High On-Clopidogrel Reactivity in Patients with Atrial Fibrillation Undergoing Percutaneous Coronary Intervention

D. Trenk, D. Duerschmied, S. Leggewie, 2022, Journal of clinical medicine.

Drug interaction between propafenone and metoprolol.

D. Trenk, H. Roskamm, F. Wagner, 1987, British journal of clinical pharmacology.

Predictors of high-sensitivity cardiac troponin in stable patients undergoing coronary angiography.

F. Neumann, M. Amann, D. Trenk, 2016, EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology.

Impact of On-Clopidogrel Platelet Reactivity on Incidence of Peri-Interventional Bleeding in Patients Undergoing Transcatheter Aortic Valve Implantation

F. Neumann, D. Trenk, W. Hochholzer, 2020, Journal of clinical medicine.

Impact of On-clopidogrel Platelet Reactivity on Incidence of Hypo-attenuated Leaflet Thickening after Transcatheter Aortic Valve Implantation

F. Neumann, D. Trenk, P. Ruile, 2018 .

Temporal variability in the antiplatelet effects of clopidogrel and aspirin after elective drug-eluting stent implantation

G. Stone, A. Kirtane, F. Neumann, 2015, Thrombosis and Haemostasis.

Updated Expert Consensus Statement on Platelet Function and Genetic Testing for Guiding P2Y12 Receptor Inhibitor Treatment in Percutaneous Coronary Intervention.

Marco Valgimigli, Gregg W Stone, Matthew J Price, 2019, JACC. Cardiovascular interventions.

Pharmacodynamics, pharmacokinetics, and safety of single-dose subcutaneous administration of selatogrel, a novel P2Y 12 receptor antagonist, in patients with chronic coronary syndromes Thrombosis and antithrombotic therapy

P. Harst, G. Dangas, V. Kunadian, 2020 .

Determinants of fibrotic atrial cardiomyopathy in atrial fibrillation. A multicenter observational study of the RETAC (reseau européen de traîtement d’arrhythmies cardiaques)-group

F. Neumann, T. Arentz, J. Albenque, 2021, Clinical Research in Cardiology.

[Clinico-pharmacologic aspects of therapy with enoximone].

D. Trenk, E. Jähnchen, 1994, Zeitschrift fur Kardiologie.

Low-dose almitrine bismesylate in the treatment of hypoxemia due to chronic obstructive pulmonary disease.

B. Winkelmann, D. Trenk, H. Kronenberger, 1994, Chest.

Monitoring anticoagulation with argatroban in critically ill patients: activated partial thromboplastin time versus diluted thrombin time

Cornelius Lehane, D. Trenk, C. Keyl, 2016, Thrombosis and Haemostasis.

Rotational thromboelastometry and conventional coagulation tests in patients undergoing major cardiac or aortic surgery: a retrospective single-center cohort study

F. Beyersdorf, D. Trenk, C. Keyl, 2021, Journal of Thrombosis and Thrombolysis.

Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel: A Study by the International Clopidogrel Pharmacogenomics Consortium

R. Altman, L. Gong, T. Klein, 2020, Clinical pharmacology and therapeutics.

The use of B-type natriuretic peptides in the detection of myocardial ischemia in settings with rapid access to coronary angiography.

D. Conen, F. Neumann, N. Jander, 2007, International journal of cardiology.

Impact of cytochrome P450 3A4-metabolized statins on the antiplatelet effect of a 600-mg loading dose clopidogrel and on clinical outcome in patients undergoing elective coronary stent placement

F. Neumann, D. Trenk, W. Hochholzer, 2007, Thrombosis and Haemostasis.

Whole blood aggregometry for evaluation of the antiplatelet effects of clopidogrel.

F. Neumann, D. Trenk, W. Hochholzer, 2007, Thrombosis research.

Apixaban and Valve Thrombosis After Transcatheter Aortic Valve Replacement: The ATLANTIS-4D-CT Randomized Clinical Trial Substudy.

E. Vicaut, P. Leprince, F. Neumann, 2022, JACC. Cardiovascular interventions.

A Pharmacodynamic Evaluation of Switching From Ticagrelor to Prasugrel in Patients With Stable Coronary Artery Disease: Results of the SWAP-2 Study

M. Effron, N. Curzen, P. Gurbel, 2013 .

Observational Study of Platelet Reactivity in Patients Presenting With ST-Segment Elevation Myocardial Infarction Due to Coronary Stent Thrombosis Undergoing Primary Percutaneous Coronary Intervention: Results From the European PREvention of Stent Thrombosis by an Interdisciplinary Global European E

W. Desmet, J. Wykrzykowska, M. Joner, 2017, JACC. Cardiovascular interventions.

Resistance to antiplatelet drugs: clopidogrel

F. Neumann, D. Trenk, C. Valina, 2008 .

Aspirin resistance an underestimated risk in patients with drug-eluting stents?

F. Neumann, D. Trenk, 2008, Journal of the American College of Cardiology.

An Underestimated Risk in Patients With Drug-Eluting Stents?*

F. Neumann, D. Trenk, 2008 .

D. Trenk, S. Øie, E. Jähnchen, 1988, The Journal of pharmacy and pharmacology.

TCT-747 Efficacy and safety of intensified antiplatelet therapy on the basis of platelet reactivity testing in patients after percutaneous coronary intervention: Systematic review and meta-analysis

M. Price, M. Valgimigli, D. Sibbing, 2012 .

Extent and spatial distribution of left atrial arrhythmogenic sites, late gadolinium enhancement at magnetic resonance imaging, and low-voltage areas in patients with persistent atrial fibrillation: comparison of imaging vs. electrical parameters of fibrosis and arrhythmogenesis.

P. Kohl, M. Haissaguerre, P. Jais, 2019, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

The Duration of the Amplified Sinus-P-Wave Identifies Presence of Left Atrial Low Voltage Substrate and Predicts Outcome After Pulmonary Vein Isolation in Patients With Persistent Atrial Fibrillation.

F. Neumann, T. Arentz, A. Jadidi, 2018, JACC. Clinical electrophysiology.

Echocardiographic and Electrocardiographic Determinants of Atrial Cardiomyopathy Identify Patients with Atrial Fibrillation at Risk for Left Atrial Thrombogenesis

F. Neumann, T. Arentz, A. Jadidi, 2022, Journal of clinical medicine.

Short-term hemodynamic, anti-ischemic, and antianginal effects of pirsidomine, a new sydnonimine.

D. Trenk, H. Roskamm, E. Jähnchen, 1996, The American journal of cardiology.

Ultrastructural, transcriptional, and functional differences between human reticulated and non‐reticulated platelets

F. Neumann, B. Grüning, L. Hein, 2020, Journal of thrombosis and haemostasis : JTH.

Mechanism of Cephalosporin‐induced Hypoprothrombinemia: Relation to Cephalosporin Side Chain, Vitamin K Metabolism, and Vitamin K Status

M. Shearer, E. Ritz, D. Trenk, 1988, Journal of clinical pharmacology.

Important reduction of the radiation dose for pulmonary vein isolation using a multimodal approach

T. Arentz, A. Jadidi, D. Trenk, 2018, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

Alteration of von Willebrand Factor after Transcatheter Aortic Valve Replacement in the Absence of Paravalvular Regurgitation

F. Neumann, F. Beyersdorf, D. Trenk, 2018, Thrombosis and Haemostasis.

Do Atrial Differences in Endothelial Damage, Leukocyte and Platelet Activation, or Tissue Factor Activity Contribute to Chamber‐Specific Thrombogenic Status in Patients with Atrial Fibrillation?

T. Arentz, O. Morel, D. Trenk, 2014, Journal of cardiovascular electrophysiology.

Pharmacokinetics and Pharmacodynamics of the 5‐HT2 Receptor Antagonist Ketanserin in Man

W. Kirch, T. Meinertz, D. Trenk, 1983, Journal of cardiovascular pharmacology.

Double-blind comparison of haloperidol decanoate and fluphenazine decanoate effectiveness, side-effects, dosage and serum levels during a six months' treatment for relapse prevention.

H. Möller, Werner Kissling, D. Trenk, 1985, Pharmacopsychiatry.

Cytochrome P450 2C19 681G>A polymorphism and high on-clopidogrel platelet reactivity associated with adverse 1-year clinical outcome of elective percutaneous coronary intervention with drug-eluting or bare-metal stents.

M. Fromm, F. Neumann, D. Trenk, 2008, Journal of the American College of Cardiology.

Determination of the anti-ischemic activity of nebivolol in comparison with atenolol.

D. Trenk, H. Roskamm, E. Jähnchen, 1994, International journal of cardiology.

Dose-Dependent β-Sympatholytic Activity of Nebivolol in Comparison with Atenolol

D. Trenk, M. Buschmann, E. Jähnchen, 1991 .

Validating left atrial fractionation and low-voltage substrate during atrial fibrillation and sinus rhythm—A high-density mapping study in persistent atrial fibrillation

T. Arentz, A. Jadidi, D. Westermann, 2022, Frontiers in Cardiovascular Medicine.

[Pharmacology and pharmacokinetics of enoximone].

D. Trenk, E. Jähnchen, 1991, Zeitschrift für Kardiologie.

Histopathological evaluation of thrombus in patients presenting with stent thrombosis. A multicenter European study: a report of the prevention of late stent thrombosis by an interdisciplinary global European effort consortium†

W. Desmet, J. Wykrzykowska, V. Ntziachristos, 2015, European heart journal.

Pharmacokinetics and pharmacodynamics of ramipril and piretanide administered alone and in combination

D. Trenk, E. Jähnchen, H. Luus, 2004, European Journal of Clinical Pharmacology.

Impact of cytochrome P450 2C19 loss-of-function polymorphism and of major demographic characteristics on residual platelet function after loading and maintenance treatment with clopidogrel in patients undergoing elective coronary stent placement.

M. Fromm, F. Neumann, D. Trenk, 2010, Journal of the American College of Cardiology.

Pharmacokinetics of Tilidine in Terminal Renal Failure

D. Trenk, E. Jähnchen, U. Brennscheidt, 2001, Journal of clinical pharmacology.

Dose-dependent metabolism and hepatic distribution of phenprocoumon in rats

D. Trenk, S. Øie, E. Jähnchen, 1988, Journal of Pharmacokinetics and Biopharmaceutics.

Age‐dependent differences in the effect of phenprocoumon on the vitamin K1‐epoxide cycle in rats †

F. Oesch, D. Trenk, E. Jähnchen, 1980, The Journal of pharmacy and pharmacology.

Cellular damage, platelet activation, and inflammatory response after pulmonary vein isolation: a randomized study comparing radiofrequency ablation with cryoablation.

T. Arentz, O. Morel, D. Trenk, 2012, Heart rhythm.

Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate.

Deepak L. Bhatt, M. Price, R. Becker, 2010, Journal of the American College of Cardiology.

Predicted and measured plasma propofol concentration and bispectral index during deep sedation in patients with impaired left ventricular function.

D. Trenk, C. Keyl, C. Wiesenack, 2009, Journal of cardiothoracic and vascular anesthesia.

Absorption of mexiletine after treatment with gastric antacids.

T. Meinertz, D. Trenk, W. Kasper, 1982, British journal of clinical pharmacology.

Identification of 5-HT3 receptors on human platelets: Increased surface immunoreactivity after activation with adenosine diphosphate (ADP) and thrombin receptor-activating peptide (TRAP)

F. Neumann, B. Fiebich, D. Trenk, 2008, Thrombosis and Haemostasis.

Effects of aspirin and desmopressin on platelet reactivity in patients undergoing cardiac surgery with extracorporeal circulation

D. Trenk, C. Keyl, Eliane Kmitta, 2010, Thrombosis and Haemostasis.

Plasma protein binding of azapropazone in patients with kidney and liver disease.

T. Meinertz, D. Trenk, K. Breuing, 1981, British journal of clinical pharmacology.

Effect of serum protein binding on pharmacokinetics and anticoagulant activity of phenprocoumon in rats

D. Trenk, E. Jähnchen, 1980, Journal of Pharmacokinetics and Biopharmaceutics.

Analysis of the amplified p-wave enables identification of patients with atrial fibrillation during sinus rhythm

T. Arentz, D. Westermann, D. Trenk, 2023, Frontiers in Cardiovascular Medicine.

Comparison of various late gadolinium enhancement magnetic resonance imaging methods with high-definition voltage and activation mapping for detection of atrial cardiomyopathy.

R. M. Figueras i Ventura, F. Neumann, T. Arentz, 2022, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

Structural and electrophysiological determinants of atrial cardiomyopathy identify remodeling discrepancies between paroxysmal and persistent atrial fibrillation

A. Loewe, T. Arentz, D. Westermann, 2023, Frontiers in Cardiovascular Medicine.

Prospective, randomised trial of the time dependent antiplatelet effects of 500 mg and 250 mg acetylsalicylic acid i. v. and 300 mg p. o. in ACS (ACUTE)

R. Erbel, T. Münzel, T. Hohlfeld, 2017, Thrombosis and Haemostasis.

Time Dependence of Platelet Inhibition After a 600-mg Loading Dose of Clopidogrel in a Large, Unselected Cohort of Candidates for Percutaneous Coronary Intervention

F. Neumann, D. Trenk, W. Hochholzer, 2005, Circulation.

Pharmacokinetics of Mesalazine Pellets in Children With Inflammatory Bowel Disease

M. Benninga, K. Dilger, D. Trenk, 2004, Inflammatory bowel diseases.

Large platelets but not putative endothelial progenitor cells are associated with low strut coverage after drug-eluting stent implantation.

H. Binder, F. Neumann, M. Amann, 2015, International journal of cardiology.

Disposition of vitamin K1 after intravenous and oral administration to subjects on phenprocoumon therapy

D. Trenk, T. Guentert, S. Øie, 1988 .

Possible coumarin-like mechanism of action for cephalosporins

T. Meinertz, D. Trenk, K. Andrassy, 1984, Klinische Wochenschrift.

Efficacy and safety of intensified antiplatelet therapy on the basis of platelet reactivity testing in patients after percutaneous coronary intervention: systematic review and meta-analysis.

M. Price, M. Valgimigli, D. Sibbing, 2013, International journal of cardiology.

Age and outcomes following guided de-escalation of antiplatelet treatment in acute coronary syndrome patients undergoing percutaneous coronary intervention: results from the randomized TROPICAL-ACS trial

M. Hadamitzky, J. Mehilli, F. Neumann, 2018, European heart journal.

Diurnal Variability of On-Treatment Platelet Reactivity in Clopidogrel versus Prasugrel Treated Acute Coronary Syndrome Patients: A Pre-Specified TROPICAL-ACS Sub-Study

K. Huber, D. Sibbing, T. Geisler, 2019, Thrombosis and Haemostasis.

Evaluation of an Alternative Staining Method Using SYTO 13 to Determine Reticulated Platelets

D. Trenk, T. Nührenberg, C. Stratz, 2019, Thrombosis and Haemostasis.

The impact of pharmacist/physician care on quality of life in elderly heart failure patients: results of the PHARM‐CHF randomized controlled trial

R. Wachter, S. Anker, F. Koehler, 2020, ESC heart failure.

The anti-inflammatory effects of the 5-HT3 receptor antagonist tropisetron are mediated by the inhibition of p38 MAPK activation in primary human monocytes

B. Fiebich, R. Akundi, D. Trenk, 2012, Brain, Behavior, and Immunity.

[Clinical pharmacology of current antiplatelet drugs].

D. Trenk, W. Hochholzer, C. Valina, 2014, Herz.

Relationship between pharmacokinetics and pharmacodynamics of molsidomine and its metabolites in humans.

T. Meinertz, D. Trenk, E. Jähnchen, 1985, American heart journal.

Genotype-Phenotype Association and Impact on Outcomes following Guided De-Escalation of Anti-Platelet Treatment in Acute Coronary Syndrome Patients: The TROPICAL-ACS Genotyping Substudy

M. Hadamitzky, M. Gawaz, D. Sibbing, 2018, Thrombosis and Haemostasis.

Pharmacokinetics and haemodynamic effects of ISDN following different dosage forms and routes of administration

D. Trenk, R. Bonn, E. Jähnchen, 2004, European Journal of Clinical Pharmacology.

Comparison of the effects of two different galenical preparations of glyceryl trinitrate on pulmonary artery pressure and on the finger pulse curve

D. Trenk, H. Roskamm, M. Buschmann, 2004, European Journal of Clinical Pharmacology.

Gender and Outcomes following Guided De-Escalation of Antiplatelet Treatment in Acute Coronary Syndrome Patients: The TROPICAL-ACS Gender Substudy

M. Hadamitzky, K. Huber, D. Sibbing, 2019, Thrombosis and Haemostasis.

Hemostasis in patients with normal and impaired renal function under treatment with cefodizime

D. Trenk, K. Andrassy, E. Jähnchen, 2005, Infection.

Improved method for quantitative analysis of vitamin K1 and vitamin K1 2,3-epoxide in human plasma by electron-capture gas-liquid capillary chromatography.

D. Trenk, E. Jähnchen, H. Bechtold, 1984, Journal of chromatography.

Ticagrelor or Prasugrel in Patients With Acute Coronary Syndromes and Diabetes Mellitus.

H. Schunkert, A. Kastrati, F. Neumann, 2020, JACC. Cardiovascular interventions.

Impact of On-Clopidogrel Platelet Reactivity on Incidence of Hypoattenuated Leaflet Thickening After Transcatheter Aortic Valve Replacement.

F. Neumann, D. Trenk, P. Ruile, 2019, JACC. Cardiovascular interventions.

PHARMacy‐based interdisciplinary program for patients with Chronic Heart Failure (PHARM‐CHF): rationale and design of a randomized controlled trial, and results of the pilot study

S. Anker, F. Koehler, U. Laufs, 2018, European journal of heart failure.

Impact of reticulated platelets on antiplatelet response to thienopyridines is independent of platelet turnover

F. Neumann, M. Amann, D. Trenk, 2016, Thrombosis and Haemostasis.

Prolongation of the PQ interval as a measure of therapeutic inequivalence between two formulations of diltiazem

D. Trenk, S. Santos, E. Jähnchen, 2004, European Journal of Clinical Pharmacology.

Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, diltiazem, and sparteine

M. Eichelbaum, D. Trenk, H. Roskamm, 1987, Klinische Wochenschrift.

Cyclic interconversion of vitamin K1 and vitamin K1 2,3-epoxide in man.

M. Rowland, T. Meinertz, D. Trenk, 1983, British journal of clinical pharmacology.

Drug–Drug Interaction between Antiplatelet Therapy and Lipid-Lowering Agents (Statins and PCSK9 Inhibitors)

K. Schrör, F. Verheugt, D. Trenk, 2022, Thrombosis and Haemostasis.

Sequential First‐Pass Metabolism of Nortilidine: The Active Metabolite of the Synthetic Opioid Drug Tilidine

D. Trenk, S. Øie, E. Jähnchen, 2002, Journal of clinical pharmacology.

Uncontrolled Diabetes Mellitus Has No Major Influence on the Platelet Transcriptome

H. Binder, F. Neumann, B. Grüning, 2018, BioMed research international.

37th International Symposium on Intensive Care and Emergency Medicine (part 3 of 3)

Hester F. Lingsma, J. M. Vieira, M. Majdan, 2017, Critical Care.

High-sensitivity cardiac troponin for risk prediction in patients with and without coronary heart disease.

F. Neumann, M. Amann, D. Trenk, 2014, International journal of cardiology.

Impact of Reticulated Platelets on the Antiplatelet Effect of the Intravenous P2Y12-Receptor Inhibitor Cangrelor

F. Neumann, K. Mashayekhi, D. Trenk, 2018, Thrombosis and Haemostasis.

Clinical implications of drug–drug interactions with P2Y12 receptor inhibitors

S. Krähenbühl, A. Michelson, D. Trenk, 2014, Journal of thrombosis and haemostasis : JTH.

Prognostic Value of High-Sensitivity Cardiac Troponin T Compared with Risk Scores in Stable Cardiovascular Disease.

F. Neumann, H. Katus, E. Giannitsis, 2017, The American journal of medicine.

Non-invasive body surface electrocardiographic imaging for diagnosis of atrial cardiomyopathy.

F. Neumann, A. Loewe, T. Arentz, 2021, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

Platelet activation and myocardial necrosis in patients undergoing radiofrequency and cryoablation of isthmus-dependent atrial flutter.

F. Neumann, T. Arentz, D. Trenk, 2007, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

O. Dössel, F. Neumann, A. Loewe, 2020, Scientific Reports.

The anti-inflammatory effects of the 5-HT3 receptor antagonist tropisetron are mediated by the inhibition of p38 MAPK activation in primary human monocytes

B. Fiebich, R. Akundi, D. Trenk, 2013, Brain, behavior, and immunity.

Drug–Drug Interaction between Antiplatelet Therapy and Lipid-Lowering Agents (Statins and PCSK9 Inhibitors)

K. Schrör, F. Verheugt, D. Trenk, 2022, Thrombosis and Haemostasis.

Pharmacokinetic characterization of the antiarrhythmic drug diprafenone in man

D. Trenk, F. Wagner, E. Jähnchen, 2004, European Journal of Clinical Pharmacology.

Drug-eluting coronary stents: as safe as bare-metal stents, but optimized antiplatelet therapy may further improve clinical outcome

F. Neumann, D. Trenk, Franz-Josef Neumann, 2008, European Journal of Clinical Pharmacology.

Micro-array profiling exhibits remarkable intra-individual stability of human platelet micro-RNA

H. Binder, B. Fiebich, D. Trenk, 2012, Thrombosis and Haemostasis.

Comparison of the Initial Hemodynamic Effects of Immediate‐Release versus Sustained‐Release Isosorbide‐5‐Mononitrate following Single Oral Doses

D. Trenk, M. Hinder, R. Bonn, 2000, Journal of clinical pharmacology.

Digital pulse plethysmography as a non-invasive method for predicting drug-induced changes in left ventricular preload

D. Trenk, H. Roskamm, E. Jähnchen, 1996, European Journal of Clinical Pharmacology.

Factors responsible for interindividual differences in the dose requirement of phenprocoumon

T. Meinertz, H. Althen, D. Trenk, 2004, European Journal of Clinical Pharmacology.

Lack of Effect of Cefixime on the Metabolism of Vitamin K1

D. Trenk, F. Wagner, E. Jähnchen, 1990, Journal of clinical pharmacology.

CYCLICINTERCONVERSIONOFVITAMINK1AND VITAMIN K12,3-EPOXIDE INMAN

M. Rowland, T. Meinertz, D. Trenk, 1983 .

[Cardiovascular pharmacotherapy in old age].

D. Trenk, M. Schulz, U. Laufs, 2023, Herz.

Controlled type II diabetes mellitus has no major influence on platelet micro-RNA expression

Harald Binder, Asit Kumar, H. Binder, 2013, Thrombosis and Haemostasis.

Cilostazol: the "poor man's" replacement of drug-eluting stents and balloons?

D. Trenk, T. Zeller, 2013, Circulation.

37th International Symposium on Intensive Care and Emergency Medicine (part 3 of 3)

Hester F. Lingsma, J. M. Vieira, M. Majdan, 2017, Critical Care.

Pharmacodynamic evaluation of switching from ticagrelor to prasugrel in patients with stable coronary artery disease: Results of the SWAP-2 Study (Switching Anti Platelet-2).

M. Effron, N. Curzen, D. Angiolillo, 2014, Journal of the American College of Cardiology.

Reduced-Function CYP2C19 Genotype and Risk of Adverse Clinical Outcomes Among Patients Treated With Clopidogrel Predominantly for PCI

E. Antman, J. Mega, B. Horne, 2017 .

Accuracy of a Rapid Diagnostic Test for the Presence of Direct Oral Factor Xa or Thrombin Inhibitors in Urine—A Multicenter Trial

P. Verhamme, I. Ahrens, H. Darius, 2019, Thrombosis and Haemostasis.