Dennis Lee

发表

Antiinflammatory Activity in Animal Models Receptor That Demonstrates Antagonist of the Anaphylatoxin C3a Identification of a Selective Nonpeptide

McCafferty, J. Adams, K. Ward, 2001 .

In situ assembly of enzyme inhibitors using extended tethering

W. Delano, E. Gordon, Joni W. Lam, 2003, Nature Biotechnology.

The discovery of tertiary-amine LXR agonists with potent cholesterol efflux activity in macrophages.

M. Jaye, S. Thompson, Dennis Lee, 2009, Bioorganic & medicinal chemistry letters.

Prospects for caspase inhibitors.

T. O'Brien, Dennis Lee, 2004, Mini reviews in medicinal chemistry.

Novel Rho Kinase Inhibitors with Anti-inflammatory and Vasodilatory Activities

D. Behm, R. Bentley, C. Doe, 2007, Journal of Pharmacology and Experimental Therapeutics.

Assessing a novel depot delivery strategy for noninvasive administration of VEGF/PDGF RTK inhibitors for ocular neovascular disease.

P. Coffey, P. Adamson, D. Shima, 2013, Investigative ophthalmology & visual science.

In Vivo Imaging of Small Molecular Weight Peptides for Targeted Renal Drug Delivery: A Study in Normal and Polycystic Kidney Diseased Mice

A. Nadin, S. Lenhard, Shih-Hsun Cheng, 2019, The Journal of Pharmacology and Experimental Therapeutics.

Discovery of GSK2193874: An Orally Active, Potent, and Selective Blocker of Transient Receptor Potential Vanilloid 4.

Carl A. Brooks, D. Holt, W. Bao, 2017, ACS medicinal chemistry letters.

Antiinflammatory Activity in Animal Models Receptor That Demonstrates Antagonist of the Anaphylatoxin C3a Identification of a Selective Nonpeptide

McCafferty, J. Adams, K. Ward, 2001 .

Rho kinase inhibitors as potential therapeutic agents for cardiovascular diseases.

Dennis Lee, E. Hu, 2003, Current opinion in investigational drugs.

CCR2 receptor antagonists: optimization of biaryl sulfonamides to increase activity in whole blood.

J. Briand, C. Chung, N. Varga, 2011, Bioorganic & medicinal chemistry letters.

Identification of potent and novel small-molecule inhibitors of caspase-3.

W. Delano, E. Gordon, Joni W. Lam, 2003, Bioorganic & medicinal chemistry letters.

Identification of a Selective Nonpeptide Antagonist of the Anaphylatoxin C3a Receptor That Demonstrates Antiinflammatory Activity in Animal Models

J. Adams, K. Ward, H. Sarau, 2001, The Journal of Immunology.

2,4,5- triarylimidazole inhibitors of IL-1 biosynthesis

Jerry L. Adams, John C. Lee, J. Adams, 1995 .

Potent, selective and orally bioavailable dihydropyrimidine inhibitors of Rho kinase (ROCK1) as potential therapeutic agents for cardiovascular diseases.

S. Semus, D. Behm, R. Bentley, 2008, Journal of medicinal chemistry.

Tetrazole is an effective Sn-3 phosphate replacement in substrate analog inhibitors of 14 kDa phospholipase A2

J. Adams, L. Marshall, Dennis Lee, 1997 .

Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitors.

M. Jaye, J. Trill, R. Annan, 2009, Bioorganic & medicinal chemistry letters.

Development of dihydropyridone indazole amides as selective Rho-kinase inhibitors.

S. Semus, D. Behm, R. Bentley, 2007, Journal of medicinal chemistry.

Rho kinase as potential therapeutic target for cardiovascular diseases: opportunities and challenges

Dennis Lee, E. Hu, 2005, Expert opinion on therapeutic targets.

Discovery of aminofurazan-azabenzimidazoles as inhibitors of Rho-kinase with high kinase selectivity and antihypertensive activity.

S. Semus, M. Head, D. Behm, 2007, Journal of medicinal chemistry.

Identification of potent and selective small-molecule inhibitors of caspase-3 through the use of extended tethering and structure-based drug design.

Daniel A Erlanson, Christian Wiesmann, W. Delano, 2002, Journal of medicinal chemistry.

Regulation of stress-induced cytokine production by pyridinylimidazoles; inhibition of CSBP kinase.

J. Boehm, S. Kassis, John C. Lee, 1997, Bioorganic & medicinal chemistry.

Topical Drug Delivery to the Back of the Eye

T. Gadek, Dennis Lee, 2011 .