J. Poirier

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Comparative Pharmacokinetics of Intravenous Propranolol in Obese and Normal Volunteers

J. Barré, G. Cheymol, J. Poirier, 1987, Journal of clinical pharmacology.

Variability of cytochrome P450 1A2 activity over time in young and elderly healthy volunteers.

T. Simon, C. Funck-Brentano, J. Poirier, 2001, British journal of clinical pharmacology.

Amiodarone pharmacokinetics in coronary patients: Differences between acute and one-month chronic dosing

P. Coumel, G. Cheymol, J. Poirier, 2010, European Journal of Drug Metabolism and Pharmacokinetics.

Suppression of arrhythmias within hours after a single oral dose of amiodarone and relation to plasma and myocardial concentrations.

P. Coumel, P. Maison-Blanche, P. Menasche, 1985, The American journal of cardiology.

Week 96 efficacy of lopinavir/ritonavir monotherapy in virologically suppressed patients with HIV: a randomized non-inferiority trial (ANRS 140 DREAM)

C. Fagard, Y. Yazdanpanah, B. Spire, 2018, The Journal of antimicrobial chemotherapy.

Optimisation of Itraconazole Therapy Using Target Drug Concentrations

G. Cheymol, J. Poirier, Georges Cheymol, 1998, Clinical pharmacokinetics.

Measurement of CYP2D6 and CYP3A4 activity in vivo with dextromethorphan: sources of variability and predictors of adverse effects in 419 healthy subjects

P. Böelle, C. Funck-Brentano, J. Poirier, 2005, European Journal of Clinical Pharmacology.

Arrhythmogenic activities of antiarrhythmic drugs in conscious hypokalemic dogs with atrioventricular block: comparison between quinidine, lidocaine, flecainide, propranolol and sotalol.

J. Davy, G. Cheymol, J. Poirier, 1991, The Journal of pharmacology and experimental therapeutics.

Effects of chronic treatment by amiodarone on transmural heterogeneity of canine ventricular repolarization in vivo: interactions with acute sotalol.

F. Charpentier, J. Poirier, J. Weissenburger, 1999, Cardiovascular research.

Efficacy and tolerance of telaprevir in HIV-hepatitis C virus genotype 1-coinfected patients failing previous antihepatitis C virus therapy: 24-week results

J. Poirier, K. Lacombe, A. Boyd, 2013, AIDS.

Epidemiological aspects of diabetes in Cameroon: what is the role of tropical diabetes?

J. Poirier, B. Bauduceau, M. Ducorps, 1997, Diabetes & metabolism.

Influence of liver fibrosis stage on plasma levels of efavirenz in HIV-infected patients with chronic hepatitis B or C.

J. Poirier, K. Lacombe, P. Girard, 2009, The Journal of antimicrobial chemotherapy.

Pharmacokinetics of β-adrenoceptor blockers in obese and normal volunteers

P. Carrupt, B. Testa, E. Snoeck, 1997 .

Assessment of CYP2D6 and CYP2C19 activity in vivo in humans: A cocktail study with dextromethorphan and chloroguanide alone and in combination

C. Funck-Brentano, J. Poirier, C. Verstuyft, 1999, Clinical pharmacology and therapeutics.

Pharmacokinetic study and cardiovascular monitoring of nebivolol in normal and obese subjects

E. Snoeck, J. Levron, G. Cheymol, 1997, European Journal of Clinical Pharmacology.

Effect of interferon α‐ribavirin bitherapy on cytochrome P450 1A2 and 2D6 and N‐acetyltransferase‐2 activities in patients with chronic active hepatitis C

C. Funck-Brentano, O. Chazouilleres, J. Poirier, 2002, Clinical pharmacology and therapeutics.

Influence of amiodarone on genetically determined drug metabolism in humans

A. Leenhardt, C. Funck-Brentano, J. Poirier, 1991, Clinical pharmacology and therapeutics.

Quantification of the HIV-integrase inhibitor raltegravir (MK-0518) in human plasma by high-performance liquid chromatography with fluorescence detection.

J. Poirier, P. Jaillon, P. Robidou, 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Asymmetric hydrolysis of pro-chiral 3,3-disubstituted 2,4-diacetoxycyclohexa-1,4-dienes

J. Poirier, P. Renouf, P. Duhamel, 1997 .

Combination of Sotalol and Quinidine in a Canine Model of Torsades de Pointes

J. Davy, G. Cheymol, J. Poirier, 1998, Journal of cardiovascular electrophysiology.

Pharmacokinetics of intravenous bisoprolol in obese and non-obese volunteers

G. Cheymol, J. Poirier, F. Hugues, 2004, European Journal of Clinical Pharmacology.

[Pharmacokinetic study of sotalol administered intravenously to healthy men. Application of high performance liquid chromatography (author's transl)].

G. Cheymol, J. Poirier, P. Jaillon, 1981, Therapie.

Asymmetric synthesis by enzymatic hydrolysis of prochiral dienol diacetate.

J. Poirier, D. Cahard, P. Renouf, 1994 .

Influence of CYP 2 D 6-dependent metabolism on the steady-state pharmacokinetics and pharmacodynamics of metoprolol and nicardipine , alone and in combination

J. Poirier, P. Jaillon, D. Decolin, 2006 .

Influence of CYP2D6-dependent metabolism on the steady-state pharmacokinetics and pharmacodynamics of metoprolol and nicardipine, alone and in combination.

C. Funck-Brentano, J. Poirier, P. Jaillon, 1993, British journal of clinical pharmacology.

Transitory increased blood pressure after upper airway surgery for snoring and sleep apnea correlates with the apnea-hypopnea respiratory disturbance index.

B. Fleury, M. Ouayoun, J. Poirier, 2003, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Experimental Arrhythmogenicity of Quinidine: Effects of Dose and Route of Administration

J. Davy, G. Cheymol, J. Poirier, 1989 .

Sustained Increase of HDL Cholesterol Over a 72-Week Period in HIV-Infected Patients Exposed to an Antiretroviral Regimen Including Lopinavir/Ritonavir

J. Poirier, K. Lacombe, P. Benlian, 2008, Journal of the International Association of Physicians in AIDS Care.

Pharmacokinetics of beta-adrenoceptor blockers in obese and normal volunteers.

P. Carrupt, B. Testa, E. Snoeck, 1997, British journal of clinical pharmacology.

Rapid and sensitive column liquid chromatographic determination of sotalol in plasma.

G. Cheymol, J. Poirier, M. Lebot, 1989, Journal of chromatography.

Polymorphism of dextromethorphan metabolism: relationships between phenotype, genotype and response to the administration of encainide in humans.

G. Béréziat, T. Simon, C. Funck-Brentano, 1992, The Journal of pharmacology and experimental therapeutics.

Pharmacokinetic and pharmacodynamic drug interactions between digoxin and macrogol 4000, a laxative polymer, in healthy volunteers.

C. Funck-Brentano, J. Poirier, P. Jaillon, 1999, British journal of clinical pharmacology.

Critical drug interaction between ritonavir-boosted atazanavir regimen and non-nucleoside reverse transcriptase inhibitors.

J. Poirier, G. Pialoux, P. Jaillon, 2006, AIDS.

Effects of malnutrition on cytochrome P450 1A2 activity in elderly patients.

B. Hamon-Vilcot, F. Piette, T. Simon, 2004, Therapie.

A Facile Isomerization Procedure for the Access to Thermodynamic Silyl Enol Ethers

J. Poirier, G. Dujardin, A. Deyine, 1998 .

Conjugate addition of furans to enones or their synthetic equivalents

J. Poirier, G. Dujardin, 1987 .

2-Alkoxy-3-oxoalkyl-tetrahydropyrans and -tetrahydrofurans: versatile intermediates in heterocyclic synthesis

J. Poirier, G. Dujardin, G. Plé, 1995 .

Lewis acid catalysed Michael-type addition. A new regio- and diastereo-selective annulation method using methyl vinyl ketone

J. Poirier, L. Hennequin, G. Dujardin, 1992 .

1,5-Dicarbonyl compounds : A general preparation method

J. Poirier, L. Hennequin, P. Duhamel, 1986 .

SYNTHESIS AND REACTIONS OF FUNCTIONALIZED SILYLENOL ETHERS. A REVIEW

J. Poirier, 1988 .

2-Substituted tetrahydrofurans of known absolute stereochemistry by ScN' chirality transfer

J. Poirier, G. Stork, 1983 .

Synthesis of racemic nitramine, isonitramine and sibirine

J. Poirier, L. Duhamel, P. Duhamel, 2005 .

A Facile Isomerization Procedure for the Access to Thermodynamic Silyl Enol Ethers.

J. Poirier, G. Dujardin, A. Deyine, 1998 .

Unprecedented route to enolates from silyl enol ethers and enol acetates : reaction with hard and soft electrophiles

J. Poirier, D. Cahard, P. Duhamel, 1993 .

Regression d'heterocycle a partir de sels d'iminiums α-halogenes et d'enamines β-halogenees de la serie heterocycliques

J. Poirier, L. Duhamel, 1976 .

[Applications analytiques des oxocarbones-I: composition et constantes de stabilite des complexes molybdiques de l'ion bromanilate: dosage spectrophotometrique du molybdene(VI)].

J. Poirier, J. Verchere, 1979, Talanta.

[Applications analytiques des oxocarbones-II: composition des complexes tungstiques des ions bromanilate et chloranilate: dosage spectrophotometrique du tungstene(VI)].

J. Poirier, J. Verchere, 1979, Talanta.

Alkali Enolates of Unsymmetrical Ketones from Silyl Enol Ethers. Highly Regioselective Aldol Reactions Dependent on the Nature of the Cation

J. Poirier, D. Cahard, P. Duhamel, 1996 .

β‐Iodotrimethylsilylenol Ether and α‐Iodoaldehydes and Ketones from α‐Chloro‐ and α‐Bromocarbonyl Compounds.

J. Poirier, 1986 .

β-Lithiated Enamines as Enolate Equivalents in Michael Additions to Enoates. A Novel Entry to Mono- and Disubstituted 5-Oxo Esters

D. Enders, J. Poirier, G. Raabe, 1991 .

.beta.-Lithioenamines from .beta.-chloroenamine. A convenient preparation method of hindered ketones

J. Poirier, L. Duhamel, 1979 .

.beta.-Lithioenamines. New reagents for synthesis

J. Poirier, L. Duhamel, 1977 .

COMPARATIVE HEMODYNAMIC STUDY OF A NEW AMINOSTEROID: LND‐623 WITH ITS 20α‐ISOMER: LND‐369, AND WITH DIGOXIN AND DIGOXIGENIN‐RHAMNOSIDE IN THE ANESTHETIZED DOG

G. Cheymol, J. Poirier, P. Jaillon, 1989, Fundamental & clinical pharmacology.

A simple approach to 1-azaspiro[4,5]decanes

P. Granger, J. Poirier, L. Duhamel, 1979 .

Plasma itraconazole concentrations in patients with neutropenia: advantages of a divided daily dosage regimen.

G. Cheymol, J. Poirier, P. Tilleul, 1997, Therapeutic drug monitoring.

A rapid and specific liquid chromatographic assay for the determination of itraconazole and hydroxyitraconazole in plasma.

G. Cheymol, J. Poirier, 1997, Therapeutic drug monitoring.

Determination of Itraconazole and Its Active Metabolite in Plasma by Column Liquid Chromatography

G. Cheymol, J. Poirier, P. Descamps, 1994, Therapeutic drug monitoring.

[Prevention of aspergillosis with itraconazole in neutropenic patients: importance of drug monitoring].

G. Cheymol, J. Poirier, 1999, Bulletin de l'Academie nationale de medecine.

A SIMPLE APPROACH TO 1-AZASPIRO(4,5)DECANES

P. Granger, J. Poirier, L. Duhamel, 1980 .

Marked intra- and inter-patient variability of itraconazole steady state plasma concentrations.

G. Cheymol, J. Poirier, F. Isnard, 1996, Therapie.

Complexation and redox reactions of molybdenum ions with a quinonic reducible ligand in aqueous solution

J. Poirier, J. Verchere, 1986 .

Aldolisation-type reaction versus Michael-type addition. Hemiacetal vinylogs : versatile synthons

J. Poirier, J. Guillemont, P. Duhamel, 1993 .

Polyunsaturated aldehydes by direct polyvinylogation of carbonyl compounds using functionalized phosphonates.

J. Poirier, G. Plé, Y. Ramondenc, 1990 .

Aldolization-Type Reaction versus Michael-Type Addition. Hemiacetal Vinylogs: Versatile Synthons.

J. Poirier, J. Guillemont, P. Duhamel, 1993 .

Polyethylenic Aldehydes by Direct Polyvinylogation of Carbonyl Compounds Using Functionalized Phosphonates.

J. Poirier, J. Guillemont, G. Plé, 1991 .

Pharmacokinetics of intravenous and oral pentoxifylline in healthy volunteers and in cirrhotic patients

G. Cheymol, J. Poirier, R. Poupon, 1990, Clinical pharmacology and therapeutics.

Rapid and sensitive high-performance liquid chromatographic determination of bisoprolol in plasma and urine.

G. Cheymol, J. Poirier, P. Jaillon, 1988, Journal of chromatography.

Comparison of four beta‐blockers as assessed by 24‐hour ECG recording

P. Coumel, P. Maison-Blanche, J. Poirier, 1986, Clinical pharmacology and therapeutics.

The configuration of β‐halogenoenamines. The use of a new procedure for NOE measurements

P. Granger, J. Poirier, S. Chapelle, 1980 .

Sodium Amide in Organic Synthesis

J. Poirier, 1997 .

Highly selective ring-opening of 1,3,3-trihalogenoepoxycyclohexanes by boron trihalides; methodology for the determination of the regioselectivity in the cyclisation of 2,2,6,6-tetrahalogenocyclohexanols

J. Poirier, B. Leblond, P. Duhamel, 1994 .

Nucleophilic fluorination by selective ring opening of α-halooxiranes

J. Poirier, B. Leblond, P. Duhamel, 1993 .

Highly Selective Ring‐Opening of 1,3,3‐Trihalogenoepoxycyclohexanes by Boron Trihalides; Methodology for the Determination of the Regioselectivity in the Cyclization of 2,2,6,6‐ Tetrahalogenocyclohexanols.

J. Poirier, B. Leblond, P. Duhamel, 1995 .

A general synthesis of (2Z)-terpenoic acids

J. Poirier, D. Cahard, L. Duhamel, 2000 .

Simple and Simultaneous Determination of the HIV-Protease Inhibitors Amprenavir, Atazanavir, Indinavir, Lopinavir, Nelfinavir, Ritonavir and Saquinavir Plus M8 Nelfinavir Metabolite and the Nonnucleoside Reverse Transcriptase Inhibitors Efavirenz and Nevirapine in Human Plasma by Reversed-Phase Liqu

J. Poirier, P. Jaillon, P. Robidou, 2005, Therapeutic drug monitoring.

Determination of indinavir in plasma by solid-phase extraction and column liquid chromatography.

J. Poirier, P. Jaillon, P. Robidou, 1999, Therapeutic drug monitoring.

The impact of CCL3L1 copy number in an HIV-1-infected white population

F. Lescure, J. Poirier, G. Pialoux, 2010, AIDS.

High Variability of Plasma Drug Concentrations in Dual Protease Inhibitor Regimens

W. Rozenbaum, J. Poirier, G. Pialoux, 2003, Antimicrobial Agents and Chemotherapy.

The pharmacokinetics of d-sotalol and d,l-sotalol in healthy volunteers

G. Cheymol, J. Poirier, B. Lecocq, 2004, European Journal of Clinical Pharmacology.

Nucleophilic Fluorination by Selective Ring Opening of α‐ Halooxiranes.

J. Poirier, B. Leblond, P. Duhamel, 1993 .

Application of the retroaldol reaction to asymmetric synthesis: a new concept in organic syntheses

J. Poirier, L. Toupet, L. Duhamel, 1999 .

Cardiac electrophysiological effects of propafenone and its 5-hydroxylated metabolite in the conscious dog.

J. Poirier, C. Chassaing, M. Boucher, 1996, European journal of pharmacology.

Comparison of Electrophysiological Effects of Quinidine and Hydroquinidine in Anesthetized Dogs

J. Davy, J. Poirier, M. Biour, 1988 .

Rapid and sensitive liquid chromatographic assay of mefenamic acid in plasma.

G. Cheymol, J. Poirier, M. Lebot, 1992, Therapeutic drug monitoring.

Analysis of encainide and its three major metabolites in plasma by column liquid chromatography.

G. Cheymol, J. Poirier, M. Lebot, 1990, Journal of chromatography.

Mexiletine antagonizes effects of sotalol on QT interval duration and its proarrhythmic effects in a canine model of torsade de pointes.

J Weissenburger, J. Davy, J. Poirier, 1995, Journal of the American College of Cardiology.

Ventricular Arrhythmias: A Double-Blind Placebo-Controlled Crossover Study

C. Libersa, J. Poirier, B. Dupuis, 2010 .

Comparative study of encainide and disopyramide in chronic ventricular arrhythmias: a double-blind placebo-controlled crossover study.

C. Libersa, J. Poirier, B. Dupuis, 1985, Journal of the American College of Cardiology.

Long-term efficacy and safety of oral encainide in the treatment of chronic ventricular ectopic activity: relationship to plasma concentrations--a French multicenter trial.

P. Coumel, J. Valty, G. Cheymol, 1985, American heart journal.

Comparison of Propranolol and Sotalol Pharmacokinetics in Obese Subjects

J. Barré, G. Cheymol, J. Poirier, 1990, The Journal of pharmacy and pharmacology.

Cyclosporine in Whole Blood: Drug Monitoring Difficulties and Presentation of a Reliable Normal‐Phase Liquid Chromatographic Assay

J. Poirier, Georges Cheymol, Martine Lebot, 1994, Therapeutic drug monitoring.

The pharmacokinetics of dexfenfluramine in obese and non-obese subjects.

J Weissenburger, G Cheymol, G. Cheymol, 1995, British journal of clinical pharmacology.

Atazanavir urinary stones in an HIV-infected patient.

I. Petit, J. Poirier, P. Girard, 2006, AIDS.

Rate dependence of sotalol-induced prolongation of ventricular repolarization during exercise in humans.

A. Mallet, C. Funck-Brentano, J. Poirier, 1991, Circulation.

Simultaneous Determination of the Six HIV Protease Inhibitors (Amprenavir, Indinavir, Lopinavir, Nelfinavir, Ritonavir, and Saquinavir) Plus M8 Nelfinavir Metabolite and the Nonnucleoside Reverse Transcription Inhibitor Efavirenz in Human Plasma by Solid-Phase Extraction and Column Liquid Chromatogr

J. Poirier, P. Jaillon, P. Robidou, 2002, Therapeutic drug monitoring.

Study of cyclosporin A blood level during the early post-liver-transplantation period.

A. Lienhart, B. Nordlinger, P. Balladur, 1993, Therapie.

[Electrophysiological effects of intravenous sotalol. Relation with plasma levels].

J. Valty, G. Cheymol, J. Poirier, 1985, Archives des maladies du coeur et des vaisseaux.

Oral Pharmacokinetics of Bisoprolol in Resting and Exercising Healthy Volunteers

J. Poirier, B. Lecocq, P. Jaillon, 1991, Journal of cardiovascular pharmacology.

Impact of reduced dosing of lopinavir/ritonavir in virologically controlled HIV-infected patients: the Kaledose trial.

J. Poirier, K. Lacombe, M. Valantin, 2010, The Journal of antimicrobial chemotherapy.

Simultaneous determination of the five HIV-protease inhibitors: amprenavir, indinavir, nelfinavir, ritonavir, and saquinavir in human plasma by solid-phase extraction and column liquid chromatography.

J. Poirier, P. Jaillon, P. Robidou, 2000, Therapeutic drug monitoring.

Efficacy of darunavir despite low plasma trough levels during late pregnancy in an HIV-hepatitis C virus-infected patient.

J. Poirier, P. Girard, L. Morand‐Joubert, 2009, AIDS.

Is diclofenac a valuable CYP2C9 probe in humans?

M. Loriot, C. Funck-Brentano, J. Poirier, 2001, European Journal of Clinical Pharmacology.

Lack of interaction between atazanavir and proton pump inhibitors in HIV-infected patients treated with ritonavir-boosted atazanavir.

J. Poirier, J. Meynard, P. Bonnard, 2006, Journal of acquired immune deficiency syndromes.

Prediction of sotalol‐induced maximum steady‐state QTc prolongation from single‐dose administration in healthy volunteers

C. Funck-Brentano, J. Poirier, P. Jaillon, 1992, Clinical pharmacology and therapeutics.

Comparison of the Cardiac Electrophysiological Effects of Flecainide and Hydroquinidine in Anesthetized Dog: Concentration‐Response Relationship

J. Davy, G. Cheymol, J. Poirier, 1990, Journal of cardiovascular pharmacology.

Proton pump inhibitors do not reduce atazanavir concentrations in HIV-infected patients treated with ritonavir-boosted atazanavir.

J. Poirier, G. Pialoux, P. Jaillon, 2005, AIDS.