Guang Yang

发表

Problems and Solutions in Click Chemistry Applied to Drug Probes

Honggang Zhou, Wei-long Zhong, Bo Sun, 2016, Scientific Reports.

Applications and Perspectives of Cascade Reactions in Bacterial Infection Control

H. C. van der Mei, Yijin Ren, H. Busscher, 2020, Frontiers in Chemistry.

Regorafenib-Attenuated, Bleomycin-Induced Pulmonary Fibrosis by Inhibiting the TGF-β1 Signaling Pathway

Honggang Zhou, Guang Yang, Cheng Yang, 2021, International journal of molecular sciences.

Synergy between “Probiotic” Carbon Quantum Dots and Ciprofloxacin in Eradicating Infectious Biofilms and Their Biosafety in Mice

H. C. van der Mei, Yijin Ren, H. Busscher, 2021, Pharmaceutics.

Salidroside improves the hypoxic tumor microenvironment and reverses the drug resistance of platinum drugs via HIF-1α signaling pathway

Wei-long Zhong, Yan-rong Liu, Guang Yang, 2018, EBioMedicine.

Ellagic Acid Attenuates BLM-Induced Pulmonary Fibrosis via Inhibiting Wnt Signaling Pathway

Xiaowei Liu, Hailong Li, Honggang Zhou, 2020, Frontiers in Pharmacology.

5α-Epoxyalantolactone Inhibits Metastasis of Triple-Negative Breast Cancer Cells by Covalently Binding a Conserved Cysteine of Annexin A2.

Xiang Liu, Cheng Lu, Guang Yang, 2021, Journal of medicinal chemistry.

First orally bioavailable prodrug of proteolysis targeting chimera (PROTAC) degrades cyclin-dependent kinases 2/4/6 in vivo.

Cheng Yang, Zhiwen Tang, Guang Yang, 2020, European journal of medicinal chemistry.

A Novel Anticancer Stem Cell Compound Derived from Pleuromutilin Induced Necroptosis of Melanoma Cells.

Zhiwen Tang, Ningning Li, Guang Yang, 2021, Journal of medicinal chemistry.

Liposomes with Water as a pH‐Responsive Functionality for Targeting of Acidic Tumor and Infection Sites

Yijin Ren, H. Busscher, Linqi Shi, 2021, Angewandte Chemie.

A novel Anti-Cancer Stem Cells compound optimized from the natural symplostatin 4 scaffold inhibits Wnt/β-catenin signaling pathway.

Honggang Zhou, Cheng Lu, Guang Yang, 2018, European journal of medicinal chemistry.

PKM2 promotes pulmonary fibrosis by stabilizing TGF-β1 receptor I and enhancing TGF-β1 signaling

Honggang Zhou, Guang Yang, Cheng Yang, 2022, Science advances.

Design and synthesis of Leukotriene A4 hydrolase inhibitors to alleviate idiopathic pulmonary fibrosis and acute lung injury.

Honggang Zhou, Xiang Liu, Cheng Lu, 2020, European journal of medicinal chemistry.

Deglycosylated Azithromycin Targets Transgelin to Enhance Intestinal Smooth Muscle Function

Bangmao Wang, Honggang Zhou, A. Roberts, 2020, iScience.

XPO1 inhibition synergizes with PARP1 inhibition in small cell lung cancer by targeting nuclear transport of FOXO3a.

Li Lin, T. Sun, Guang Yang, 2021, Cancer letters.

A novel epigenetic drug conjugating flavonoid and HDAC inhibitor confers to suppression of acute myeloid leukemogenesis.

Juan Zhang, Guang Yang, Cheng Yang, 2021, Clinical science.

Flavonoids from Mirabilis himalaica.

Guang Yang, Xuedong Yang, Xian Gao, 2018, Fitoterapia.

Synthesis of enantiopure 18F-trifluoromethyl cysteine as a structure-mimetic amino acid tracer for glioma imaging

Guang Yang, Shende Jiang, Ganghua Tang, 2019, Theranostics.

Design and synthesis of novel Flavone-based histone deacetylase inhibitors antagonizing activation of STAT3 in breast cancer.

Juan Zhang, Guang Yang, Cheng Yang, 2020, European journal of medicinal chemistry.

Discovery of novel and bioavailable histone deacetylases and cyclin-dependent kinases dual inhibitor to impair the stemness of leukemia cells.

Cheng Yang, Guang Yang, Yue Sun, 2023, European journal of medicinal chemistry.

Self-targeting, zwitterionic micellar dispersants enhance antibiotic killing of infectious biofilms—An intravital imaging study in mice

H. C. van der Mei, Yijin Ren, H. Busscher, 2020, Science Advances.

In vitro and in vivo degradation of programmed cell death ligand 1 (PD-L1) by a proteolysis targeting chimera (PROTAC).

Guang Yang, Cheng Yang, Jiefu Wang, 2021, Bioorganic chemistry.

Proteolysis-Targeting Chimera (PROTAC) Modification of Dovitinib Enhances the Antiproliferative Effect against FLT3-ITD-Positive Acute Myeloid Leukemia Cells.

Guang Yang, Cheng Yang, Xiaoji Wang, 2021, Journal of medicinal chemistry.

Synthesis and discovery of a drug candidate for treatment of idiopathic pulmonary fibrosis through inhibition of TGF-β1 pathway.

Honggang Zhou, Cheng Lu, Zhun Bi, 2018, European journal of medicinal chemistry.

Dihydroartemisinin inhibits EMT induced by platinum-based drugs via Akt–Snail pathway

Honggang Zhou, Wei-long Zhong, Shuang Chen, 2017, Oncotarget.

Structure optimization and discovery of novel compound for the treatment of insertion mutations within exon 20 of EGFR and HER2.

L. Zuo, Guang Yang, Fei Hou, 2023, Bioorganic & medicinal chemistry.

Self‐Targeted Co‐Delivery of an Antibiotic and a Cancer‐Chemotherapeutic from Synthetic Liposomes for the Treatment of Infected Tumors

H. C. van der Mei, Yijin Ren, H. Busscher, 2023, Advanced Functional Materials.

Targeted Drug-Loaded Chemical Probe Staining Assay to Predict Therapy Response and Function as an Independent Pathological Marker

Honggang Zhou, Wei-long Zhong, Bo Sun, 2019, iScience.

Discovery and Optimization of a Novel 2H-Pyrazolo[3,4-d]pyrimidine Derivative as a Potent Irreversible Pan-Fibroblast Growth Factor Receptor Inhibitor.

Honggang Zhou, Guang Yang, Cheng Yang, 2021, Journal of medicinal chemistry.

Design and discovery of new selective and potent VEGF receptor 2 tyrosine kinase inhibitors.

Guang Yang, Yue Meng, Yue Sun, 2023, Bioorganic & medicinal chemistry.

Vorapaxar proven to be a promising candidate for pulmonary fibrosis by intervening in the PAR1/JAK2/STAT1/3 signaling pathway-an experimental in vitro and vivo study.

Cheng Yang, Honggang Zhou, Guang Yang, 2023, European journal of pharmacology.

Discovery of a novel Pleuromutilin derivative as anti-IPF lead compound via high-throughput assay.

Cheng Yang, Honggang Zhou, Guang Yang, 2022, European journal of medicinal chemistry.

Design, synthesis and evaluation of a pyrazolo[3,4-d]pyrimidine derivative as a novel and potent TGFβ1R1 inhibitor.

Guang Yang, Mingming Wei, Yulin Liu, 2024, European journal of medicinal chemistry.

Synthesis and Discovery Novel Anti-Cancer Stem Cells Compounds Derived from the Natural Triterpenoic Acids.

Honggang Zhou, Cheng Lu, Guang Yang, 2018, Journal of Medicinal Chemistry.