C. Grootaert

发表

Microplastics in the human digestive environment: A focus on the potential and challenges facing in vitro gut model development.

E. Fournier, L. Etienne-Mesmin, C. Grootaert, 2021, Journal of hazardous materials.

Co-Ingestion of Black Carrot and Strawberry. Effects on Anthocyanin Stability, Bioaccessibility and Uptake

Senem Kamiloglu, M. Hendrickx, J. Van Camp, 2020, Foods.

Use of metabolomics and fluorescence recovery after photobleaching to study the bioavailability and intestinal mucus diffusion of polyphenols from cauliflower waste

J. Camp, N. Rigby, G. Smagghe, 2015 .

Butyrate-producing bacteria supplemented in vitro to Crohn’s disease patient microbiota increased butyrate production and enhanced intestinal epithelial barrier integrity

D. Laukens, M. De Vos, T. van de Wiele, 2017, Scientific Reports.

Comparison of prebiotic effects of arabinoxylan oligosaccharides and inulin in a simulator of the human intestinal microbial ecosystem.

W. Verstraete, J. Delcour, M. Marzorati, 2009, FEMS microbiology ecology.

The prenylflavonoid isoxanthohumol from hops (Humulus lupulus L.) is activated into the potent phytoestrogen 8-prenylnaringenin in vitro and in the human intestine.

W. Verstraete, S. Rabot, T. van de Wiele, 2006, The Journal of nutrition.

Nutrient Physiology , Metabolism , and Nutrient-Nutrient Interactions The Prenylflavonoid Isoxanthohumol from Hops ( Humulus lupulus L . ) Is Activated into the Potent Phytoestrogen 8-Prenylnaringenin In Vitro and in the Human Intestine 1

T. Wiele, W. Verstraete, S. Rabot, 2006 .

Sustained accumulation of prelamin A and depletion of lamin A/C both cause oxidative stress and mitochondrial dysfunction but induce different cell fates

W. D. De Vos, A. Rajković, J. Broers, 2015, Nucleus.

Aronia (Aronia melanocarpa) Polyphenols Modulate the Microbial Community in a Simulator of the Human Intestinal Microbial Ecosystem (SHIME) and Decrease Secretion of Proinflammatory Markers in a Caco‐2/endothelial Cell Coculture Model

Senem Kamiloglu, T. van de Wiele, J. Van Camp, 2018, Molecular nutrition & food research.

Egg-derived bioactive peptides with ACE-inhibitory properties: a literature update.

J. Van Camp, G. Smagghe, S. Voorspoels, 2017, Food & function.

Adherence and viability of intestinal bacteria to differentiated Caco-2 cells quantified by flow cytometry.

W. Verstraete, T. van de Wiele, N. Boon, 2011, Journal of microbiological methods.

Self-assembly, functionality, and in-vitro properties of quercetin loaded nanoparticles based on shellac-almond gum biological macromolecules.

K. Dewettinck, P. Van der Meeren, J. Van Camp, 2019, International journal of biological macromolecules.

Biocatalytic Synthesis of the Rare Sugar Kojibiose: Process Scale-Up and Application Testing.

Senem Kamiloglu, K. Dewettinck, T. van de Wiele, 2017, Journal of agricultural and food chemistry.

Gastrointestinal Simulation Model TWIN-SHIME Shows Differences between Human Urolithin-Metabotypes in Gut Microbiota Composition, Pomegranate Polyphenol Metabolism, and Transport along the Intestinal Tract.

J. Van Camp, G. Smagghe, J. Espín, 2017, Journal of agricultural and food chemistry.

Ferulic acid-4-O-sulfate rather than ferulic acid relaxes arteries and lowers blood pressure in mice.

G. Williamson, J. Van Camp, G. Smagghe, 2017, The Journal of nutritional biochemistry.

Angiopoietin-like protein 4: health effects, modulating agents and structure–function relationships

W. Verstraete, T. van de Wiele, C. Grootaert, 2012, Expert review of proteomics.

Bacterial monocultures, propionate, butyrate and H2O2 modulate the expression, secretion and structure of the fasting-induced adipose factor in gut epithelial cell lines.

W. Verstraete, T. van de Wiele, A. Vercoutter-Edouart, 2011, Environmental microbiology.

Vasorelaxant activity of twenty-one physiologically relevant (poly)phenolic metabolites on isolated mouse arteries.

G. Williamson, J. Van Camp, P. Kroon, 2017, Food & function.

A two-front nutritional environment fuels colorectal cancer: perspectives for dietary intervention

O. De Wever, J. Van Camp, C. Grootaert, 2021, Trends in Endocrinology & Metabolism.

Development of an oral mucosa model to study host-microbiome interactions during wound healing

T. Wiele, S. Swift, F. Kerckhof, 2014, Applied Microbiology and Biotechnology.

Intracellular quercetin accumulation and its impact on mitochondrial dysfunction in intestinal Caco-2 cells.

A. Rajković, N. Boon, G. Goeminne, 2021, Food research international.

Flavonoid interactions during digestion, absorption, distribution and metabolism: a sequential structure–activity/property relationship-based approach in the study of bioavailability and bioactivity

J. Camp, G. Smagghe, C. Grootaert, 2015, Drug metabolism reviews.

Two- and three-dimensional quantitative structure–permeability relationship of flavonoids in Caco-2 cells using stepwise multiple linear regression (SMLR), partial least squares regression (PLSR), and pharmacophore (GALAHAD)-based comparative molecular similarity index analysis (COMSIA)

J. Camp, G. Smagghe, C. Grootaert, 2015, Medicinal Chemistry Research.

Bioenergetic Status of the Intestinal and Hepatic Cells after Short Term Exposure to Fumonisin B1 and Aflatoxin B1

A. Rajković, C. Grootaert, Mohamed F. Abdallah, 2022, International journal of molecular sciences.

Cell line-dependent increase in cellular quercetin accumulation upon stress induced by valinomycin and lipopolysaccharide, but not by TNF-α.

A. Rajković, T. van de Wiele, J. Van Camp, 2019, Food research international.

Quercetin mitigates valinomycin-induced cellular stress via stress-induced metabolism and cell uptake.

A. Rajković, T. van de Wiele, J. Van Camp, 2016, Molecular nutrition & food research.

Anthocyanin Absorption and Metabolism by Human Intestinal Caco-2 Cells—A Review

E. Çapanoğlu, Senem Kamiloglu, J. Van Camp, 2015, International journal of molecular sciences.

Review on the Use of Cell Cultures to Study Metabolism, Transport, and Accumulation of Flavonoids: From Mono-Cultures to Co-Culture Systems

J. Camp, G. Smagghe, C. Grootaert, 2015 .

A Critical Evaluation of In Vitro Hesperidin 2S Bioavailability in a Model Combining Luminal (Microbial) Digestion and Caco‐2 Cell Absorption in Comparison to a Randomized Controlled Human Trial

J. Van Camp, G. Smagghe, S. Voorspoels, 2018, Molecular nutrition & food research.

Resveratrol improves TNF-α-induced endothelial dysfunction in a coculture model of a Caco-2 with an endothelial cell line.

E. Çapanoğlu, Senem Kamiloglu, J. Van Camp, 2016, The Journal of nutritional biochemistry.

Aronia (Aronia melanocarpa) phenolics bioavailability in a combined in vitro digestion/Caco-2 cell model is structure and colon region dependent

Senem Kamiloglu, J. Camp, G. Smagghe, 2017 .

Quercetin Mitigates Endothelial Activation in a Novel Intestinal-Endothelial-Monocyte/Macrophage Coculture Setup

N. Boon, J. Van Camp, G. Smagghe, 2022, Inflammation.

Flow Cytometric Method for the Detection of Flavonoids in Cell Lines

T. van de Wiele, J. Van Camp, G. Smagghe, 2016, Journal of biomolecular screening.

Chronic exposure to short-chain fatty acids modulates transport and metabolism of microbiome-derived phenolics in human intestinal cells

G. Williamson, S. Tumova, J. Van Camp, 2017, The Journal of nutritional biochemistry.

Microbiome Metabolic Potency Towards Plant Bioactives and Consequences for Health Effects

T. Wiele, C. Grootaert, 2018, Health Consequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids.

Cu isotope fractionation response to oxidative stress in a hepatic cell line studied using multi-collector ICP-mass spectrometry

J. Camp, F. Vanhaecke, C. Grootaert, 2018, Analytical and Bioanalytical Chemistry.

Anti‐inflammatory potential of black carrot (Daucus carota L.) polyphenols in a co‐culture model of intestinal Caco‐2 and endothelial EA.hy926 cells

E. Çapanoğlu, Senem Kamiloglu, J. Van Camp, 2017, Molecular nutrition & food research.

Impact of heat and enzymatic treatment on ovalbumin amyloid-like fibril formation and enzyme-induced gelation

J. Delcour, F. Rousseau, K. Dewettinck, 2022, Food Hydrocolloids.

Rational Design of Amyloid-Like Fibrillary Structures for Tailoring Food Protein Techno-Functionality and Their Potential Health Implications.

J. Delcour, F. Rousseau, P. Van der Meeren, 2018, Comprehensive reviews in food science and food safety.

Foodborne pathogens in the plastisphere: Can microplastics in the food chain threaten microbial food safety?

A. Rajković, M. Callens, C. Grootaert, 2022, Trends in Food Science & Technology.

Sweet Biotechnology: Enzymatic Production and Digestibility Screening of Novel Kojibiose and Nigerose Analogues.

J. Van Camp, C. Grootaert, Koen Beerens, 2022, Journal of agricultural and food chemistry.

Chemical composition, antioxidant, antimicrobial and antiproliferative activities of the extracts isolated from the pomace of rowanberry (Sorbus aucuparia L.).

J. Van Camp, C. Grootaert, Petras Rimantas Venskutonis, 2020, Food research international.

J. Camp, G. Smagghe, C. Grootaert, 2015, Medicinal Chemistry Research.

Flavonoids and cellular stress: a complex interplay affecting human health

J. Van Camp, G. Smagghe, C. Grootaert, 2021, Critical reviews in food science and nutrition.

Natural Fe isotope fractionation in an intestinal Caco-2 cell line model

J. Camp, F. Vanhaecke, C. Grootaert, 2017 .

Development of an oral mucosa model to study host-microbiome interactions during wound healing

T. Wiele, S. Swift, F. Kerckhof, 2014, Applied Microbiology and Biotechnology.

Synthesis and biological assessment of novel N-(hydroxy/methoxy)alkyl β-enaminone curcuminoids.

J. Van Camp, C. Grootaert, M. D’hooghe, 2016, Bioorganic & medicinal chemistry letters.

Anthocyanin determination in blueberry extracts from various cultivars and their antiproliferative and apoptotic properties in B16-F10 metastatic murine melanoma cells.

R. Pop, A. Pintea, C. Grootaert, 2013, Phytochemistry.

Synthesis of 1,4-thiazepane-based curcuminoids with promising anticancer activity.

J. Van Camp, C. Grootaert, K. Van Hecke, 2019, Chemistry.

Protein hydrolysate from canned sardine and brewing by-products improves TNF-α-induced inflammation in an intestinal–endothelial co-culture cell model

J. Camp, C. Grootaert, I. Ferreira, 2018, European Journal of Nutrition.

The response of five intestinal cell lines to anoxic conditions in vitro

A. Rajković, T. van de Wiele, M. Calatayud, 2019, Biology of the cell.

Synthesis of novel curcuminoids accommodating a central β-enaminone motif and their impact on cell growth and oxidative stress.

J. Van Camp, C. Grootaert, M. D’hooghe, 2016, European journal of medicinal chemistry.

Cell Systems to Investigate the Impact of Polyphenols on Cardiovascular Health

E. Çapanoğlu, Senem Kamiloglu, J. Van Camp, 2015, Nutrients.

Microbial metabolism and prebiotic potency of arabinoxylan oligosaccharides in the human intestine

T. Wiele, W. Verstraete, J. Delcour, 2007 .

The Intestinal Fate of Citrus Flavanones and Their Effects on Gastrointestinal Health

J. Camp, A. Masclee, D. Jonkers, 2019, Nutrients.

The intestinal environment in health and disease - recent insights on the potential of intestinal bacteria to influence human health.

W. Verstraete, M. Marzorati, T. van de Wiele, 2009, Current pharmaceutical design.

Bioaccessibility of Polyphenols from Plant-Processing Byproducts of Black Carrot (Daucus carota L.).

E. Çapanoğlu, Senem Kamiloglu, T. van de Wiele, 2016, Journal of agricultural and food chemistry.

Method for beta-carotene extraction from processed baby foods as a model for plant-based fatty food products.

J. Van Camp, C. Grootaert, B. De Meulenaer, 2021, Food research international.

Prebiotics to manage the microbial control of energy homeostasis.

T. Wiele, M. Marzorati, P. van den Abbeele, 2011, Beneficial microbes.

Propionate as a health-promoting microbial metabolite in the human gut.

W. Verstraete, T. van de Wiele, C. Grootaert, 2011, Nutrition reviews.

Microbial inhibition of oral epithelial wound recovery: potential role for quorum sensing molecules?

T. van de Wiele, C. Stevens, C. Grootaert, 2015, AMB Express.

Synthesis of Novel Aza‐aromatic Curcuminoids with Improved Biological Activities towards Various Cancer Cell Lines

J. Van Camp, C. Grootaert, T. Desmet, 2018, ChemistryOpen.

Rare mono- and disaccharides as healthy alternative for traditional sugars and sweeteners?

J. Van Camp, C. Grootaert, Amar van Laar, 2020, Critical reviews in food science and nutrition.

Microbial Community Development in a Dynamic Gut Model Is Reproducible, Colon Region Specific, and Selective for Bacteroidetes and Clostridium Cluster IX

E. Zoetendal, M. Kleerebezem, W. Verstraete, 2010, Applied and Environmental Microbiology.

In vitro model to study the modulation of the mucin-adhered bacterial community

W. Verstraete, P. van den Abbeele, T. van de Wiele, 2009, Applied Microbiology and Biotechnology.

Arabinoxylan‐oligosaccharides (AXOS) affect the protein/carbohydrate fermentation balance and microbial population dynamics of the Simulator of Human Intestinal Microbial Ecosystem

T. Wiele, W. Verstraete, J. Delcour, 2008, Microbial biotechnology.

Synthesis of Non‐Symmetrical Nitrogen‐Containing Curcuminoids in the Pursuit of New Anticancer Candidates

J. Van Camp, C. Grootaert, K. Van Hecke, 2019, ChemistryOpen.

Transepithelial transport of dry-cured ham peptides with ACE inhibitory activity through a Caco-2 cell monolayer

J. Camp, F. Toldrá, L. Mora, 2016 .

Metabolism and Health Effects of Rare Sugars in a CACO-2/HepG2 Coculture Model

D. Deforce, J. Van Camp, F. van Nieuwerburgh, 2022, Nutrients.

Quantification of egg ovalbumin hydrolysate-derived anti-hypertensive peptides in an in vitro model combining luminal digestion with intestinal Caco-2 cell transport.

J. Van Camp, G. Smagghe, S. Voorspoels, 2017, Food research international.

Rare Sugar Metabolism and Impact on Insulin Sensitivity along the Gut–Liver–Muscle Axis In Vitro

A. Rajković, J. Van Camp, C. Grootaert, 2023, Nutrients.

INTRACELLULAR ACCUMULATION OF QUERCETIN AND ITS IMPACT ON CELLULAR STRESS: AN IN VITRO STUDY

C. Grootaert, H. Vissenaekens, Hanne Criel, 2019 .

Chemopreventive effects from prebiotic inulin towards microbial 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine bioactivation

W. Verstraete, T. van de Wiele, L. Vanhaecke, 2009, Journal of applied microbiology.

Sub-Emetic Toxicity of Bacillus cereus Toxin Cereulide on Cultured Human Enterocyte-Like Caco-2 Cells

A. Rajković, B. Meulenaer, M. Uyttendaele, 2014, Toxins.

Clinical aspects of egg bioactive peptide research: a review

J. Van Camp, S. Voorspoels, G. Jacobs, 2019, International Journal of Food Science & Technology.

In vitro bioaccessibility and uptake of β-carotene from encapsulated carotenoids from mango by-products in a coupled gastrointestinal digestion/Caco-2 cell model.

T. van de Wiele, J. Van Camp, J. Ruales, 2022, Food research international.

Obesity, bacteria and fat

T. Wiele, W. Verstraete, C. Grootaert, 2010 .

Butyrate-producing bacteria supplemented in vitro to Crohn’s disease patient microbiota increased butyrate production and enhanced intestinal epithelial barrier integrity

D. Laukens, M. De Vos, T. van de Wiele, 2017, Scientific Reports.

Synthesis and cancer cell cytotoxicity of 2-aryl-4-(4-aryl-2-oxobut-3-en-1-ylidene)-substituted benzothiazepanes

J. Van Camp, D. Schols, C. Grootaert, 2023, Phytochemistry Letters.

Bioavailability and Health Impact of Ingested Amyloid-like Protein Fibrils and their Link with Inflammatory Status: a Need for More Research?

J. Delcour, F. Rousseau, J. Van Camp, 2022, Molecular nutrition & food research.

New insights into the combined toxicity of aflatoxin B1 and fumonisin B1 in HepG2 cells using Seahorse respirometry analysis and RNA transcriptome sequencing.

A. Rajković, F. van Nieuwerburgh, C. Grootaert, 2023, Environment international.

Anthocyanin determination in blueberry extracts from various cultivars and their antiproliferative and apoptotic properties in B16-F10 metastatic murine melanoma cells.

R. Pop, A. Pintea, C. Grootaert, 2013, Phytochemistry.