J. Duley

A. V. van Kuilenburg, N. Helsby, J. Duley, 2016, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Allele Frequency of Inosine Triphosphate Pyrophosphatase Gene Polymorphisms in a Japanese Population

J. Duley, L. Fairbanks, A. Marinaki, 2004, Nucleosides, nucleotides & nucleic acids.

Adenylosuccinate Lyase Deficiency—First British Case

H. Simmonds, J. Duley, M. Vincent, 2004, Nucleosides, nucleotides & nucleic acids.

Deep sequencing of the 16S ribosomal RNA of the neonatal oral microbiome: a comparison of breast-fed and formula-fed infants

J. Duley, D. Cowley, P. N. Shaw, 2016, Scientific Reports.

Novel disease-causing mutations in the dihydropyrimidine dehydrogenase gene interpreted by analysis of the three-dimensional protein structure.

Hans R Waterham, Y. Lindqvist, H. Waterham, 2002, The Biochemical journal.

S-adenosylmethionine increases erythrocyte ATP in vitro by a route independent of adenosine kinase.

H. Simmonds, J. Duley, R. Smolenski, 1990, Biochemical pharmacology.

Adenylosuccinate lyase deficiency in a Malaysian patient, with novel adenylosuccinate lyase gene mutations

J. Pitt, J. Duley, M. Thong, 2010, Journal of Inherited Metabolic Disease.

Ecto-nucleotidases in isolated intact rat vagi, nodose ganglia, and superior cervical ganglia.

J. Duley, C. Demaine, G. P. Connolly, 1997, Advances in experimental medicine and biology.

Determination of nicotinamide phosphoribosyltransferase activity in human erythrocytes: high-performance liquid chromatography-linked method.

V. Micheli, H. Simmonds, J. Duley, 1992, Analytical biochemistry.

Accelerated purine base salvage--a possible cause of elevated nucleotide pool in the erythrocytes of patients with uraemia.

H. Simmonds, B. Rutkowski, J. Duley, 1994, Advances in experimental medicine and biology.

Comparing the effects of hydrostatic high-pressure processing vs holder pasteurisation on the microbial, biochemical and digestion properties of donor human milk.

J. Duley, D. Cowley, P. N. Shaw, 2021, Food chemistry.

The Results of Different Heating Temperatures on Activities of Bioactive Proteins in Human Milk

J. Duley, D. Cowley, P. Koorts, 2022, Journal of human lactation : official journal of International Lactation Consultant Association.

Nanosecond pulsed electric field treatment of human milk: Effects on microbiological inactivation, whey proteome and bioactive protein.

Firuz Zare, J. Duley, D. Cowley, 2022, Food Chemistry.

The effect of breastmilk and saliva combinations on the in vitro growth of oral pathogenic and commensal microorganisms

J. Duley, D. Cowley, P. N. Shaw, 2018, Scientific Reports.

Preliminary Evidence for Enhanced Thymine Absorption: A Putative New Phenotype Associated With Fluoropyrimidine Toxicity in Cancer Patients

A. V. van Kuilenburg, N. Helsby, J. Duley, 2018, Therapeutic drug monitoring.

Mitochondrial disease mimicking Charcot–Marie Tooth disease

C. Sue, J. Duley, M. Needham, 2009, BMJ Case Reports.

Mechanisms of deoxyguanosine lymphotoxicity. Human thymocytes, but not peripheral blood lymphocytes accumulate deoxy-GTP in conditions simulating purine nucleoside phosphorylase deficiency.

H. Simmonds, J. Duley, A. Taddeo, 1990, Journal of immunology.

Simultaneous determination of thymine and its sequential catabolites dihydrothymine and β-ureidoisobutyrate in human plasma and urine using liquid chromatography-tandem mass spectrometry with pharmacokinetic application.

J. Duley, R. McGeary, B. Charles, 2013, Journal of pharmaceutical and biomedical analysis.

A case–control study to assess the ability of the thymine challenge test to predict patients with severe to life threatening fluoropyrimidine‐induced gastrointestinal toxicity

N. Helsby, J. Duley, M. Findlay, 2020, British journal of clinical pharmacology.

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J. Duley, 1993, BMJ.

Quantitation of Purines from Pigeon Guano and Implications for Cryptococcus neoformans Survival During Infection

J. Fraser, M. Cooper, J. Duley, 2019, Mycopathologia.

An alternative pathway of adenylate and ATP synthesis.

H. Simmonds, J. Duley, R. Smolenski, 1991, Advances in experimental medicine and biology.

Renal urate hypoexcretion preceding renal disease in a new kindred with familial juvenile gouty nephropathy (FJGN).

H. Simmonds, J. Duley, C. Chantler, 1991, Advances in experimental medicine and biology.

Succinylpurines do not modify glutamate or adenosine effects in the CNS.

H. Simmonds, J. Duley, M. Vincent, 1998, Advances in experimental medicine and biology.

Phosphoribosylpyrophosphate synthetase superactivity

J. Christodoulou, A. Brouwer, J. Duley, 2015 .

A new mechanism of toxicity of 2-chlorodeoxyadenosine (2CdA).

J. Duley, K. Fabianowska-Majewska, K. Warzocha, 1994, Advances in experimental medicine and biology.

Phosphoribosylpyrophosphate synthetase superactivity and recurrent infections is caused by a p.Val142Leu mutation in PRS‐I

S. Nabuurs, H. van Bokhoven, J. Christodoulou, 2012, American journal of medical genetics. Part A.

Allogeneic bone marrow transplantation corrects the immunodeficiency in PNP deficiency but does not reverse the neurological abnormalities

H. Simmonds, J. Duley, L. Fairbanks, 1999 .

Co-therapy with S-adenosylmethionine and nicotinamide riboside improves t-cell survival and function in Arts Syndrome (PRPS1 deficiency)

A. V. van Kuilenburg, J. Christodoulou, M. Huemer, 2021, Molecular genetics and metabolism reports.

HPLC assay of uridine monophosphate synthase (UMPS) in chorionic villus samples (CVS) and erythrocytes (RBC).

H. Simmonds, J. Duley, L. Fairbanks, 1991, Advances in Experimental Medicine and Biology.

Further evidence for a 'new' purine defect, inosine triphosphate (ITP) pyrophosphohydrolase deficiency.

V. Micheli, H. Simmonds, R. Levinsky, 1989 .

Importance of the human erythrocyte in the diagnosis of inherited purine and pyrimidine disorders.

V. Micheli, H. Simmonds, J. Duley, 1990, Biomedica biochimica acta.

Mutation in the ITPA gene predicts intolerance to azathioprine

J. Sanderson, J. Duley, T. Marinaki, 2003 .

Normal uric acid concentrations in a purine nucleoside phosphorylase (PNP) deficient child presenting with severe chicken pox, possible immunodeficiency and developmental delay.

H. Simmonds, J. Duley, L. Fairbanks, 1994, Advances in Experimental Medicine and Biology.

Treatment of zero and intermediate TPMT patients with a tailored dose of azathioprine

J. Sanderson, J. Duley, M. Escudier, 2003 .

Phosphoribosylpyrophosphate synthetase superactivity and recurrent infections is caused by a p.Val142Leu mutation in PRS‐I

S. Nabuurs, H. van Bokhoven, J. Christodoulou, 2012, American journal of medical genetics. Part A.

P072 A novel mouse model relates thiopurine hepatic sinusoidal obstructive syndrome to dose-exposure of 6-thioguanosine nucleotides

I. Winkler, M. McGuckin, T. Florin, 2012 .

Azathioprine co-therapy with allopurinol for inflammatory bowel disease: Trials and tribulations

J. Duley, A. Ansari, 2012 .

Thiopurine methyl transferase activity predicts both toxicity and clinical response to azathioprine in inflammatory bowel disease: The London IBD forum prospective study

J. Sanderson, J. Lindsay, J. Duley, 2004 .

Splitting a Therapeutic Dose of Thioguanine May Avoid Liver Toxicity and Be an Efficacious Treatment for Severe Inflammatory Bowel Disease: A 2-Center Observational Cohort Study

T. Florin, J. Duley, P. Pavlidis, 2014, Inflammatory bowel diseases.

Is thioguanine-associated sinusoidal obstruction syndrome avoidable? Lessons learned from 6-thioguanine treatment of inflammatory bowel disease and a mouse model

T. Florin, J. Duley, I. Oancea, 2012 .

Morphogenesis of B103 neuroblastoma and B103-4C its mutant derivative: modelling Lesch-Nyhan syndrome

J. Duley, G. P. Connolly, N. Stacey, 1999 .

Adenylosuccinate Lyase Deficiency — First British Case

J. Duley, L. Fairbanks, G. Berghe, 2005 .

A novel route of ATP synthesis.

H. Simmonds, J. Duley, K. Fabianowska-Majewska, 1992, Biochemical pharmacology.