S. Khochbin

发表

Regulatory cross‐talk between lysine acetylation and ubiquitination: role in the control of protein stability

C. Caron, C. Boyault, S. Khochbin, 2005, BioEssays : news and reviews in molecular, cellular and developmental biology.

Histone Acylation beyond Acetylation: Terra Incognita in Chromatin Biology

S. Khochbin, S. Rousseaux, 2015, Cell journal.

Acetylation of histone H3 at lysine 64 regulates nucleosome dynamics and facilitates transcription

Andrew J. Bannister, J. Michaelis, T. Owen-Hughes, 2014, eLife.

The Evolution of the Differentiation-Specific Histone H1 Gene Basal Promoter

S. Khochbin, M. Peretti, 1997, Journal of Molecular Evolution.

Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification

Zhike Lu, Z. Ye, Fulai Jin, 2011, Cell.

What do linker histones do in chromatin?

A. Wolffe, S. Khochbin, S. Dimitrov, 1997, BioEssays : news and reviews in molecular, cellular and developmental biology.

MS_HistoneDB, a manually curated resource for proteomic analysis of human and mouse histones

A. Panchenko, D. Landsman, A. Shaytan, 2017, Epigenetics & Chromatin.

A unified phylogeny-based nomenclature for histone variants

S. Henikoff, D. Landsman, G. Cross, 2012, Epigenetics & Chromatin.

Ectopic Activation of Germline and Placental Genes Identifies Aggressive Metastasis-Prone Lung Cancers

Elisabeth Brambilla, Sophie Rousseaux, Aurélien de Reyniès, 2013, Science Translational Medicine.

Nut Directs p300-Dependent, Genome-Wide H4 Hyperacetylation in Male Germ Cells.

Yingming Zhao, D. Panne, Minjia Tan, 2018, Cell reports.

The combined detection of Amphiregulin, Cyclin A1 and DDX20/Gemin3 expression predicts aggressive forms of oral squamous cell carcinoma

Florent Chuffart, S. Khochbin, S. Rousseaux, 2021, British Journal of Cancer.

Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6

A. Bershadsky, Ralph Mazitschek, S. Khochbin, 2009, Journal of Cell Science.

UV Laser Footprinting and Protein-DNA Crosslinking

S. Dimitrov, S. Khochbin, D. Angelov, 1999 .

Histone acetylation influences both gene expression and development of Xenopus laevis.

A. Wolffe, G. Almouzni, S. Khochbin, 1994, Developmental biology.

Cancer hallmarks sustained by ectopic activations of placenta/male germline genes

S. Khochbin, S. Rousseaux, Jin Wang, 2013, Cell cycle.

Monitoring the interaction between DNA and a transcription factor ( MEF 2 A ) using fluorescence correlation spectroscopy Suivi d ' une interaction ADN – facteur de transcription ( MEF 2 A ) par spectroscopie à corrélation de fluorescence

C. Souchier, S. Khochbin, M. Robert-Nicoud, 2009 .

Structural insights into p300 regulation and acetylation-dependent genome organisation

M. Blackledge, Yingming Zhao, D. Panne, 2022, bioRxiv.

HSP27 is a ubiquitin-binding protein involved in I-kappaBalpha proteasomal degradation.

E. Solary, C. Garrido, S. Khochbin, 2003, Molecular and cellular biology.

Induction of autophagy and autophagy‐dependent apoptosis in diffuse large B‐cell lymphoma by a new antimalarial artemisinin derivative, SM1044

O. Hermine, S. Khochbin, S. Rousseaux, 2017, Cancer medicine.

Epigenetics and human reproduction

S. Khochbin, S. Rousseaux, 2011 .

The growing landscape of tubulin acetylation: lysine 40 and many more.

S. Khochbin, K. Sadoul, 2016, The Biochemical journal.

Multiple domains of the Receptor-Interacting Protein 140 contribute to transcription inhibition.

S. Khochbin, F. Vignon, A. Boulahtouf, 2004, Nucleic acids research.

Class II Histone Deacetylases Are Directly Recruited by BCL6 Transcriptional Repressor*

S. Khochbin, F. Puvion-Dutilleul, O. Albagli, 2002, The Journal of Biological Chemistry.

Developmentally regulated expression of linker-histone variants in vertebrates.

A. Wolffe, S. Khochbin, 1994, European journal of biochemistry.

HSP27 favors ubiquitination and proteasomal degradation of p27Kip1 and helps S‐phase re‐entry in stressed cells

E. Solary, K. Nakayama, K. Nakayama, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The RNA-binding protein Mex3b regulates the spatial organization of the Rap1 pathway

D. Nègre, Julien Courchet, D. Segretain, 2014, Development.

Receptor-Independent Ectopic Activity of Prolactin Predicts Aggressive Lung Tumors and Indicates HDACi-Based Therapeutic Strategies.

E. Brambilla, C. Brambilla, Minoru Yoshida, 2015, Antioxidants & redox signaling.

Muscle hypertrophy in hypoxia with inflammation is controlled by bromodomain and extra-terminal domain proteins

R. Prinjha, U. Schlattner, C. Pison, 2017, Scientific Reports.

Inhibition of BET Proteins Reduces Right Ventricle Hypertrophy and Pulmonary Hypertension Resulting from Combined Hypoxia and Pulmonary Inflammation

R. Prinjha, U. Schlattner, C. Pison, 2018, International journal of molecular sciences.

Amphiregulin promotes resistance to gefitinib in nonsmall cell lung cancer cells by regulating Ku70 acetylation.

L. Sancey, J. Coll, V. Josserand, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

HDAC6 a new cellular stress surveillance factor

Minoru Yoshida, P. Matthias, S. Khochbin, 2008, Cell cycle.

p14 Activates a Tip60-Dependent and p53-Independent ATM/ATR/CHK Pathway in Response to Genotoxic Stress

E. Brambilla, P. Claverie, B. Eymin, 2006 .

p14ARF promotes RB accumulation through inhibition of its Tip60-dependent acetylation

E. Brambilla, P. Claverie, B. Eymin, 2006, Oncogene.

Histone Deacetylase 6 Is a FoxO Transcription Factor-dependent Effector in Skeletal Muscle Atrophy*

L. Schaeffer, M. Sandri, P. Matthias, 2014, The Journal of Biological Chemistry.

Genome-scale acetylation-dependent histone eviction during spermatogenesis.

S. Khochbin, S. Rousseaux, H. Shiota, 2014, Journal of molecular biology.

Regulation of histone H10 accumulation during induced differentiation of murine erythroleukemia cells

D. Rousseau, J. Lawrence, S. Khochbin, 1991 .

Recovery of RNA from flow-sorted fixed cells.

D. Grunwald, J. Lawrence, S. Khochbin, 1990, Cytometry.

Developmentally regulated activity of CRM1/XPO1 during early Xenopus embryogenesis.

N. Kudo, M. Yoshida, M. Callanan, 2000, Journal of cell science.

Relationship between core histone acetylation and histone H1(0) gene activity.

M. Yoshida, J. Lawrence, T. Rabilloud, 1994, European journal of biochemistry.

Chromatin-to-nucleoprotamine transition is controlled by the histone H2B variant TH2B.

Yingming Zhao, C. Petosa, Minjia Tan, 2013, Genes & development.

Identity crisis in pulmonary arterial hypertension

F. Perros, S. Provencher, S. Bonnet, 2017, Pulmonary circulation.

Combination of arsenic trioxide and Dasatinib: a new strategy to treat Philadelphia chromosome‐positive acute lymphoblastic leukaemia

S. Khochbin, S. Rousseaux, J. Mi, 2017, Journal of cellular and molecular medicine.

Histone lysine methacrylation is a dynamic post-translational modification regulated by HAT1 and SIRT2

Yingming Zhao, M. Parthun, Prabakaran Nagarajan, 2021, Cell Discovery.

Chidamide inhibits the NOTCH1-MYC signaling axis in T-cell acute lymphoblastic leukemia

Florent Chuffart, S. Khochbin, S. Rousseaux, 2021, Frontiers of Medicine.

Ectopic Expression of a Combination of 5 Genes Detects High Risk Forms of Adult T-cell Acute Lymphoblastic Leukemia

Yuan-fang Liu, M. Geng, Florent Chuffart, 2021 .

Lessons from Yeast on Emerging Roles of the ATAD2 Protein Family in Gene Regulation and Genome Organization

A. Verdel, S. Khochbin, S. Rousseaux, 2014, Molecules and cells.

Malignant genome reprogramming by ATAD2.

S. Khochbin, S. Rousseaux, F. Boussouar, 2013, Biochimica et biophysica acta.

Bromodomain‐dependent stage‐specific male genome programming by Brdt

D. Wolgemuth, J. Imbert, S. Khochbin, 2012, The EMBO journal.

In the heart of a dynamic chromatin.

S. Khochbin, 2011, Chemistry & biology.

Motor-driven marginal band coiling promotes cell shape change during platelet activation

A. Grichine, S. Khochbin, Boubou Diagouraga, 2014, The Journal of cell biology.

HMGB4, a Novel Member of the HMGB Family, Is Preferentially Expressed in the Mouse Testis and Localizes to the Basal Pole of Elongating Spermatids1

C. Caron, S. Khochbin, I. Davidson, 2009, Biology of reproduction.

When are the BET factors the most sensitive to bromodomain inhibitors?

S. Khochbin, 2013, Transcription.

Functional Interaction between Class II Histone Deacetylases and ICP0 of Herpes Simplex Virus Type 1

A. Epstein, Joëlle Thomas, C. Caron, 2004, Journal of Virology.

Functional Interaction between Class II Histone Deacetylases and ICP 0 of Herpes Simplex Virus Type 1

A. Epstein, Joëlle Thomas, C. Caron, 2004 .

Two Catalytic Domains Are Required for Protein Deacetylation*

P. Matthias, S. Khochbin, Benoît Gilquin, 2006, Journal of Biological Chemistry.

Combined proteomic and in silico approaches to decipher post-meiotic male genome reprogramming in mice

S. Khochbin, S. Rousseaux, 2012, Systems biology in reproductive medicine.

Characterization of the tumor suppressor protein p53 as a protein kinase C substrate and a S100b-binding protein.

D. Grunwald, C. Delphin, J. Lawrence, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Transcription factor dimerization activates the p300 acetyltransferase

E. Ortega, A. Holehouse, D. Panne, 2018, Nature.

Brief report HDAC6 controls the kinetics of platelet activation

P. Matthias, B. Polack, S. Khochbin, 2012 .

Optimized outcome prediction of oncogenetic mutations in non-early T-cell precursor acute lymphoblastic leukemia.

S. Khochbin, S. Rousseaux, J. Mi, 2022, Immunobiology.

Histone acetylation-mediated chromatin compaction during mouse spermatogenesis.

C. Caron, S. Khochbin, S. Rousseaux, 2006, Ernst Schering Research Foundation workshop.

HDAC6-induced premature chromatin compaction in mouse oocytes and fertilised eggs

A. Verdel, S. Khochbin, D. Seigneurin-Berny, 2003, Zygote.

Characterization of Post-Meiotic Male Germ Cell Genome Organizational States.

S. Khochbin, S. Rousseaux, T. Buchou, 2018, Methods in molecular biology.

Purification and Analysis of Male Germ Cells from Adult Mouse Testis.

Minjia Tan, S. Khochbin, S. Rousseaux, 2017, Methods in molecular biology.

A specific CBP/p300‐dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis

S. Barral, S. Khochbin, S. Rousseaux, 2014, Andrology.

A new insight into male genome reprogramming by histone variants and histone code

S. Khochbin, S. Rousseaux, F. Boussouar, 2008, Cell cycle.

Expression of Serpinb6 serpins in germ and somatic cells of mouse gonads

J. Vassalli, S. Nef, S. Khochbin, 2006, Molecular reproduction and development.

Differentiation of NUT midline carcinoma by epigenomic reprogramming.

J. Aster, J. Bradner, S. Sallan, 2011, Cancer research.

NUT Is a Driver of p300-Mediated Histone Hyperacetylation: From Spermatogenesis to Cancer

S. Khochbin, N. Reynoird, S. Rousseaux, 2022, Cancers.

Nut Directs p 300-Depende nt , Genome-Wide H 4 Hyperacetylation in Male Germ Cells Graphical

Yingming Zhao, D. Panne, Minjia Tan, 2018 .

Effects of downregulated HDAC6 expression on the proliferation of lung cancer cells.

S. Horinouchi, T. Yao, Minoru Yoshida, 2008, Biochemical and biophysical research communications.

Flow cytofluorimetric determination of protein distribution throughout the cell cycle.

J. Lawrence, S. Khochbin, P. Albert, 1989, Cytometry.

Scientific Report

C. Caron, S. Khochbin, S. Rousseaux, 2022 .

Chromatin-associated YTHDC1 coordinates heat-induced reprogramming of gene expression.

Y. Couté, A. Verdel, Florent Chuffart, 2022, Cell reports.

[Spermiogenesis: histone acetylation triggers male genome reprogramming].

J. Thevenon, C. Caron, S. Khochbin, 2009, Gynecologie, obstetrique & fertilite.

Structural insights into p300 regulation and acetylation-dependent genome organisation

M. Blackledge, Yingming Zhao, D. Panne, 2022, Nature communications.

Mouse Oocytes and Early Embryos Express Multiple Histone H1 Subtypes1

A. Skoultchi, S. Khochbin, H. Clarke, 2003, Biology of reproduction.

HSP27 Is a Ubiquitin-Binding Protein Involved in I-κBα Proteasomal Degradation

E. Solary, C. Garrido, S. Khochbin, 2003, Molecular and Cellular Biology.

Structural insights into the regulation of acetylation-dependent genome condensation

M. Blackledge, Yingming Zhao, D. Panne, 2022, bioRxiv.

Histone crotonylation specifically marks the haploid male germ cell gene expression program

Yingming Zhao, S. Khochbin, Emilie Montellier, 2012, BioEssays : news and reviews in molecular, cellular and developmental biology.

Post-meiotic Shifts in HSPA2/HSP70.2 Chaperone Activity during Mouse Spermatogenesis*

J. Garin, L. Kuhn, M. Ferro, 2006, Journal of Biological Chemistry.

Misregulation of histone acetylation in Sertoli cell-only syndrome and testicular cancer.

M. Péoc'h, S. Khochbin, S. Rousseaux, 2003, Molecular human reproduction.

Regulated hyperacetylation of core histones during mouse spermatogenesis: involvement of histone deacetylases.

Y. Usson, S. Khochbin, S. Rousseaux, 2000, European journal of cell biology.

Site-specific introduction of an acetyl-lysine mimic into peptides and proteins by cysteine alkylation.

Ronen Marmorstein, Blair C. R. Dancy, R. Cole, 2010, Journal of the American Chemical Society.

Induction of H10‐gene expression in B16 murine melanoma cells

D. Rousseau, J. Lawrence, S. Khochbin, 1992 .

Application of bromodeoxyuridine incorporation measurements to the determination of cell distribution within the S phase of the cell cycle.

J. Lawrence, S. Khochbin, P. Albert, 1988, Cytometry.

Acetylation-Dependent Chromatin Reorganization by BRDT, a Testis-Specific Bromodomain-Containing Protein

C. Caron, S. Khochbin, S. Rousseaux, 2003, Molecular and Cellular Biology.

Establishment of male-specific epigenetic information.

C. Caron, S. Khochbin, S. Rousseaux, 2005, Gene.

Epigenetic reprogramming of the male genome during gametogenesis and in the zygote.

J. Thevenon, C. Caron, S. Khochbin, 2008, Reproductive biomedicine online.

Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains

H. Kimura, P. Cole, D. Panne, 2010, The EMBO journal.

Acetylation and phosphorylation of SRSF2 control cell fate decision in response to cisplatin

E. Brambilla, B. Eymin, C. Brambilla, 2011, The EMBO journal.

1q12 chromosome translocations form aberrant heterochromatic foci associated with changes in nuclear architecture and gene expression in B cell lymphoma

Y. Usson, J. de Vos, A. Grichine, 2010, EMBO molecular medicine.

Stress-induced transcription of satellite III repeats

M. Vigneron, B. Turner, A. Metz, 2004, The Journal of cell biology.

Histone H1 diversity: bridging regulatory signals to linker histone function.

S. Khochbin, S Khochbin, 2001, Gene.

Monitoring the interaction between DNA and a transcription factor (MEF2A) using fluorescence correlation spectroscopy.

C. Souchier, S. Khochbin, Guillaume G. Octobre, 2005, Comptes rendus biologies.

How to pack the genome for a safe trip.

C. Caron, S. Khochbin, S. Rousseaux, 2005, Progress in molecular and subcellular biology.

The role of histones in chromatin remodelling during mammalian spermiogenesis.

C. Caron, S. Khochbin, S. Rousseaux, 2004, European journal of biochemistry.

Differential Recognition of Histone H10 by Monoclonal Antibodies during Cell Differentiation and the Arrest of Cell Proliferation*

S. Khochbin, C. Gorka, M. Brocard, 1998, The Journal of Biological Chemistry.

Role of the Tetradecapeptide Repeat Domain of Human Histone Deacetylase 6 in Cytoplasmic Retention*

N. Bertos, Xiang-Jiao Yang, G. Chan, 2004, Journal of Biological Chemistry.

Active maintenance of mHDA2/mHDAC6 histone-deacetylase in the cytoplasm

Minoru Yoshida, A. Verdel, S. Khochbin, 2000, Current Biology.

Functional significance of histone deacetylase diversity.

A. Verdel, S. Khochbin, D. Seigneurin-Berny, 2001, Current opinion in genetics & development.

The histone variant macroH2A interferes with transcription factor binding and SWI/SNF nucleosome remodeling.

D. Angelov, S. Dimitrov, F. Hans, 2003, Molecular cell.

Molecular Cloning and Cell Cycle-dependent Expression of Mammalian CRM1, a Protein Involved in Nuclear Export of Proteins*

M. Yanagida, N. Kudo, S. Horinouchi, 1997, The Journal of Biological Chemistry.

Differential histone modifications mark mouse imprinting control regions during spermatogenesis

R. Feil, S. Khochbin, S. Rousseaux, 2007, The EMBO journal.

Maternal exposure to cigarette smoking induces immediate and durable changes in placental DNA methylation affecting enhancer and imprinting control regions

R. Slama, B. Heude, V. Siroux, 2019, bioRxiv.

Mechanism for Nucleocytoplasmic Shuttling of Histone Deacetylase 7*

A. Verdel, S. Khochbin, H. Juguilon, 2001, The Journal of Biological Chemistry.

Identification of a novel BET bromodomain inhibitor-sensitive, gene regulatory circuit that controls Rituximab response and tumour growth in aggressive lymphoid cancers

J. Garin, C. Petosa, M. Callanan, 2013, EMBO molecular medicine.

HDAC6–ubiquitin interaction controls the duration of HSF1 activation after heat shock

S. Khochbin, C. Vourc’h, Benoît Gilquin, 2014, Molecular biology of the cell.

HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates.

T. Yao, C. Garrido, P. Matthias, 2007, Genes & development.

Cooperative binding of two acetylation marks on a histone tail by a single bromodomain

Jeroen Krijgsveld, Karin Sadoul, Montserrat Soler-López, 2009, Nature.

Testis-specific histone variants H2AL1/2 rapidly disappear from paternal heterochromatin after fertilization.

Fang Wu, C. Caron, S. Khochbin, 2008, The Journal of reproduction and development.

Pericentric heterochromatin reprogramming by new histone variants during mouse spermiogenesis

J. Garin, J. Thevenon, L. Kuhn, 2007, The Journal of cell biology.

HDAC6–p97/VCP controlled polyubiquitin chain turnover

V. Rybin, C. Müller, E. Garman, 2006, The EMBO journal.

PenDA, a rank-based method for personalized differential analysis: Application to lung cancer

Daniel Jost, Florent Chuffart, Elisabeth Brambilla, 2020, PLoS Comput. Biol..

Phosphorylation of histone H4 Ser1 regulates sporulation in yeast and is conserved in fly and mouse spermatogenesis.

Karen Schindler, S. Berger, C. Allis, 2006, Genes & development.

Biology of Human Tumors Lung Squamous Cell Carcinomas with Basaloid Histology Represent a Speci fi c Molecular Entity

P. Hainaut, E. Brambilla, S. Lantuejoul, 2014 .

Induced malignant genome reprogramming in somatic cells by testis-specific factors.

M. Callanan, S. Khochbin, S. Rousseaux, 2011, Biochimica et biophysica acta.

[Epigenetic perturbations and cancer: innovative therapeutic strategies against cancer].

S. Khochbin, N. Reynoird, S. Rousseaux, 2010, Bulletin du cancer.

New hypotheses for large-scale epigenome alterations in somatic cancer cells: a role for male germ-cell-specific regulators.

S. Khochbin, S. Rousseaux, 2009, Epigenomics.

Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters

R. Roeder, Yingming Zhao, C. Petosa, 2016, Molecular cell.

HDAC6, at the crossroads between cytoskeleton and cell signaling by acetylation and ubiquitination

C. Boyault, S. Khochbin, K. Sadoul, 2007, Oncogene.

Identification of a New Family of Higher Eukaryotic Histone Deacetylases

A. Verdel, S. Khochbin, 1999, The Journal of Biological Chemistry.

Histone deacetylase 9 couples neuronal activity to muscle chromatin acetylation and gene expression

Laurent Schaeffer, E. Olson, L. Schaeffer, 2005, Nature Neuroscience.

mHDA1/HDAC5 Histone Deacetylase Interacts with and Represses MEF2A Transcriptional Activity*

A. Verdel, S. Khochbin, C. Lemercier, 2000, The Journal of Biological Chemistry.

Regulation of protein turnover by acetyltransferases and deacetylases.

C. Boyault, S. Khochbin, K. Sadoul, 2008, Biochimie.

Tip60 is targeted to proteasome‐mediated degradation by Mdm2 and accumulates after UV irradiation

L. Linares, M. Scheffner, D. Trouche, 2002, The EMBO journal.

p14ARF Activates a Tip60-Dependent and p53-Independent ATM/ATR/CHK Pathway in Response to Genotoxic Stress

E. Brambilla, P. Claverie, B. Eymin, 2006, Molecular and Cellular Biology.

Higher concentrations of histone macroH2A in the Barr body are correlated with higher nucleosome density

C. Souchier, S. Dimitrov, S. Khochbin, 2000, Current Biology.

Immediate and durable effects of maternal tobacco consumption alter placental DNA methylation in enhancer and imprinted gene-containing regions

R. Slama, I. Annesi-Maesano, B. Heude, 2020, BMC Medicine.

From meiosis to postmeiotic events: The secrets of histone disappearance

S. Khochbin, Emilie Montellier, N. Reynoird, 2010, The FEBS journal.

Pregnancy exposure to atmospheric pollution and meteorological conditions and placental DNA methylation.

J. Schwartz, R. Slama, B. Heude, 2018, Environment international.

Processing of p53 mRNA during induced differentiation of murine erythroleukemia cells: is an altered splicing mechanism responsible for the post-transcriptional control of gene expression?

J. Lawrence, S. Khochbin, 1988 .

The Histone Acetyltransferase, hGCN5, Interacts with and Acetylates the HIV Transactivator, Tat*

A. Favier, C. Caron, S. Khochbin, 2001, The Journal of Biological Chemistry.

Asymmetric nuclear reprogramming in somatic cell nuclear transfer?

S. Khochbin, P. Loi, G. Ptak, 2008, BioEssays : news and reviews in molecular, cellular and developmental biology.

Mice Lacking Histone Deacetylase 6 Have Hyperacetylated Tubulin but Are Viable and Develop Normally

F. Alt, Hwei-Ling Cheng, P. Matthias, 2008, Molecular and Cellular Biology.

Differences in nuclear positioning of 1q12 pericentric heterochromatin in normal and tumor B lymphocytes with 1q rearrangements

Y. Usson, M. Callanan, S. Khochbin, 2005, Genes, chromosomes & cancer.

CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin

R. Fässler, R. Massoumi, S. Khochbin, 2009, The EMBO journal.

A six gene expression signature defines aggressive subtypes and predicts outcome in childhood and adult acute lymphoblastic leukemia

B. Ycart, M. Callanan, W. Carroll, 2015, Oncotarget.

Lysine 2-hydroxyisobutyrylation is a widely distributed active histone mark.

Bing Ren, Chao Peng, Fulai Jin, 2014, Nature chemical biology.

The RNA-binding protein Mex 3 b regulates the spatial organization of the Rap 1 pathway

D. Nègre, Julien Courchet, D. Segretain, 2014 .

Bromodomain factors of BET family are new essential actors of pericentric heterochromatin transcriptional activation in response to heat shock

Z. Herceg, M. Vigneron, R. Schneider, 2017, Scientific Reports.

An antisense RNA involved in p53 mRNA maturation in murine erythroleukemia cells induced to differentiate.

J. Lawrence, S. Khochbin, Jean-Jacques Lawrence, 1989, The EMBO journal.

A transcriptomic analysis of human centromeric and pericentric sequences in normal and tumor cells

F. Berger, G. Fourel, E. Gilson, 2009, Nucleic acids research.

Structural Characterization of the Histone Variant macroH2A

K. Luger, S. Chakravarthy, C. Caron, 2005, Molecular and Cellular Biology.

The Tale of Protein Lysine Acetylation in the Cytoplasm

S. Khochbin, Boubou Diagouraga, Jin Wang, 2010, Journal of biomedicine & biotechnology.

Depletion of HDAC6 Enhances Cisplatin-Induced DNA Damage and Apoptosis in Non-Small Cell Lung Cancer Cells

G. Bepler, S. Nicosia, Shengyan Xiang, 2012, PloS one.

HDAC‐6 interacts with and deacetylates tubulin and microtubules in vivo

P. Matthias, D. Hess, C. Caron, 2003, The EMBO journal.

Early events in murine erythroleukemia cells induced to differentiate: variation of the cell cycle parameters in relation to p53 accumulation.

J. Lawrence, S. Khochbin, A. Chabanas, 1988, Experimental cell research.

Early events in murine erythroleukemia cells induced to differentiate. Accumulation and gene expression of the transformation-associated cellular protein p53.

J. Lawrence, S. Khochbin, A. Chabanas, 1988, Journal of molecular biology.

Tip60 Acetyltransferase Activity Is Controlled by Phosphorylation*

D. Trouche, J. Garin, G. Legube, 2003, The Journal of Biological Chemistry.

Histone variants: critical determinants in tumour heterogeneity

Florent Chuffart, S. Khochbin, S. Rousseaux, 2019, Frontiers of Medicine.

Loss of Histone H4K20 Trimethylation Occurs in Preneoplasia and Influences Prognosis of Non–Small Cell Lung Cancer

E. Brambilla, S. Lantuejoul, B. Eymin, 2008, Clinical Cancer Research.

Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells

S. Knapp, M. Gut, F. Cosset, 2016, Journal of molecular cell biology.

Functional characterization of ATAD2 as a new cancer/testis factor and a predictor of poor prognosis in breast and lung cancers

E. Brambilla, P. Barbry, C. Brambilla, 2010, Oncogene.

Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin.

M. Yoshida, S. Horinouchi, S. Khochbin, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Arsenic trioxide rewires mantle cell lymphoma response to bortezomib

Yuan-fang Liu, Saijuan Chen, R. Gressin, 2015, Cancer medicine.

Systematic screen reveals new functional dynamics of histones H3 and H4 during gametogenesis.

S. Berger, Jean A. Dorsey, S. Khochbin, 2010, Genes & development.

Nucleoside diphosphate kinases 1 and 2 regulate a protective liver response to a high-fat diet

C. Petosa, U. Schlattner, Y. Couté, 2023, bioRxiv.

Differential remodeling of the HIV-1 nucleosome upon transcription activators and SWI/SNF complex binding.

S. Dimitrov, J. Côté, S. Khochbin, 2000, Journal of molecular biology.

Remodeling somatic nuclei via exogenous expression of protamine 1 to create spermatid-like structures for somatic nuclear transfer

S. Khochbin, P. Loi, D. Iuso, 2016, Nature Protocols.

HIV‐1 Tat targets Tip60 to impair the apoptotic cell response to genotoxic stresses

D. Trouche, G. Legube, Minoru Yoshida, 2005, The EMBO journal.

Heat-shock factor 1 controls genome-wide acetylation in heat-shocked cells.

Karin Sadoul, Sabrina Fritah, Caroline Jolly, 2009, Molecular biology of the cell.

Histone Variant H2A.L.2 Guides Transition Protein-Dependent Protamine Assembly in Male Germ Cells.

H. Kurumizaka, Y. Couté, F. Fenaille, 2017, Molecular cell.

Chemical genomics: a key to the epigenome - an interview with Minoru Yoshida. Interview by Saadi Khochbin.

S. Khochbin, Minoru Yoshida, 2009, The International journal of developmental biology.

Histone deacetylase complexes: functional entities or molecular reservoirs

S. Khochbin, H. Kao, 2001, FEBS letters.

Editor's Note: Loss of Histone H4K20 Trimethylation Occurs in Preneoplasia and Influences Prognosis of Non–Small Cell Lung Cancer

E. Brambilla, S. Lantuejoul, B. Eymin, 2020, Clinical Cancer Research.

The origin and utility of histone deacetylases

A. Wolffe, S. Khochbin, Alan P Wolffe, 1997, FEBS letters.

Chromatin and epigenetics: dynamic organization meets regulated function.

D. Trouche, S. Dimitrov, S. Khochbin, 2003, Molecular cell.

Control of the histone-acetyltransferase activity of Tip60 by the HIV-1 transactivator protein, Tat.

S. Dimitrov, F. Hans, C. Caron, 1999, Biochemistry.

The viral control of cellular acetylation signaling

C. Caron, S. Khochbin, E. Col, 2003, BioEssays : news and reviews in molecular, cellular and developmental biology.

Assembly and mechanosensory function of focal adhesions: experiments and models.

Tom Shemesh, A. Bershadsky, M. Kozlov, 2006, European journal of cell biology.

Boyault C, Sadoul K, Pabion M, Khochbin S.. HDAC6, at the crossroads between cytoskeleton and cell signaling by acetylation and ubiquitination. Oncogene 26: 5468-5476

C. Boyault, S. Khochbin, K. Sadoul, 2007 .

Identification of Components of the Murine Histone Deacetylase 6 Complex: Link between Acetylation and Ubiquitination Signaling Pathways

J. Garin, A. Verdel, S. Khochbin, 2001, Molecular and Cellular Biology.

D. Grunwald, J. Lawrence, S. Khochbin, 1991, Experimental Cell Research.

A novel Rho-mDia2-HDAC6 pathway controls podosome patterning through microtubule acetylation in osteoclasts

F. Saltel, O. Destaing, S. Khochbin, 2005, Journal of Cell Science.

Sustaining cancer through addictive ectopic gene activation

S. Khochbin, S. Rousseaux, Jin Wang, 2014, Current opinion in oncology.

Developmental regulation and butyrate-inducible transcription of the Xenopus histone H1(0) promoter.

A. Wolffe, S. Khochbin, 1993, Gene.

Two mRNA species encoding the differentiation-associated histone H1(0) are produced by alternative polyadenylation in mouse.

D. Rousseau, J. Lawrence, S. Khochbin, 1994, European journal of biochemistry.

Seric factors influence cell cycle modifications during commitment of murine erythroleukemia cells to differentiation.

J. Lawrence, S. Khochbin, A. Chabanas, 1992, Cytometry.

In vivo destabilization of dynamic microtubules by HDAC6‐mediated deacetylation

S. Horinouchi, Minoru Yoshida, Akihisa Matsuyama, 2002, The EMBO journal.

AKR1B10, One of the Triggers of Cytokine Storm in SARS-CoV2 Severe Acute Respiratory Syndrome

J. Pépin, P. Poignard, M. Buisson, 2022, International journal of molecular sciences.

Structure of p300 in complex with acyl-CoA variants.

Yingming Zhao, E. Ortega, D. Panne, 2017, Nature chemical biology.

Parp2 is required for the differentiation of post-meiotic germ cells: identification of a spermatid-specific complex containing Parp1, Parp2, TP2 and HSPA2.

M. Mark, V. Schreiber, S. Khochbin, 2009, Experimental cell research.

Cacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsy

R. Dolmetsch, Y. Mori, V. Janssens, 2012, The EMBO journal.

HMGB 4 , a Novel Member of the HMGB Family , Is Preferentially Expressed in the Mouse Testis and Localizes to the Basal Pole of Elongating Spermatids 1

C. Caron, S. Khochbin, I. Davidson, 2009 .

Modulation of B2 containing small RNAs during induced differentiation of murine erythroleukemia cells.

D. Grunwald, J. Lawrence, S. Khochbin, 1991, Biochemical and biophysical research communications.

Real-time imaging of histone H4 hyperacetylation in living cells

Minoru Yoshida, S. Khochbin, N. Nishino, 2009, Proceedings of the National Academy of Sciences.

Accumulation of histone H1(0) during early Xenopus laevis development.

D. Grunwald, J. Lawrence, S. Khochbin, 1995, Experimental cell research.

Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution.

Yingming Zhao, Yuan-fang Liu, Minjia Tan, 2021, Cell reports.

In situ analysis of chromatin proteins during development and cell differentiation using flow cytometry.

D. Grunwald, S. Khochbin, C. Gorka, 1999, Methods in molecular biology.

Characterization of the two H1°-encoding genes from Xenopus laevis

D. Doenecke, S. Khochbin, M. Peretti, 1997 .

— Chromatin Structure and Function : Biological Implications in Epigenetics Histone variants : essential actors in male genome programming

S. Khochbin, S. Rousseaux, Sophie Barral, 2018 .

mHDA 1 / HDAC 5 Histone Deacetylase Interacts with and Represses MEF 2 A Transcriptional Activity *

A. Verdel, S. Khochbin, C. Lemercier, 2010 .

RNA-Guided Genomic Localization of H2A.L.2 Histone Variant

D. Puthier, Florent Chuffart, S. Khochbin, 2020, Cells.

A bromodomain–DNA interaction facilitates acetylation-dependent bivalent nucleosome recognition by the BET protein BRDT

V. Rybin, C. Müller, B. Simon, 2016, Nature Communications.

Exogenous Expression of Human Protamine 1 (hPrm1) Remodels Fibroblast Nuclei into Spermatid-like Structures

R. Feil, S. Khochbin, P. Loi, 2015, Cell reports.

Transcription factor dimerization activates the p300 acetyltransferase

E. Ortega, A. Holehouse, D. Panne, 2018, Nature.

Involvement of Retinoblastoma Protein and HBP1 in Histone H10 Gene Expression

Hui Zhang, A. Verdel, S. Khochbin, 2000, Molecular and Cellular Biology.

Developmentally regulated chromatin acetylation and histone H1(0) accumulation.

D. Grunwald, J. Lawrence, S. Khochbin, 1995, International Journal of Developmental Biology.

ATAD2 controls chromatin-bound HIRA turnover

A. Bougdour, C. Petosa, A. Verdel, 2021, Life science alliance.

Lung Squamous Cell Carcinomas with Basaloid Histology Represent a Specific Molecular Entity

P. Hainaut, E. Brambilla, S. Lantuejoul, 2014, Clinical Cancer Research.

HDAC6 controls the kinetics of platelet activation.

Karin Sadoul, P. Matthias, B. Polack, 2012, Blood.

A unified phylogeny-based nomenclature for histone variants

S. Henikoff, D. Landsman, G. Cross, 2012, Epigenetics & Chromatin.

Tat-controlled Protein Acetylation*

C. Caron, S. Khochbin, Benoît Gilquin, 2002, The Journal of Biological Chemistry.

Characterization of the two H1(zero)-encoding genes from Xenopus laevis.

D. Doenecke, S. Khochbin, M. Peretti, 1997, Gene.

Design and Synthesis of Cyclopeptide Analogues of the Potent Histone Deacetylase Inhibitor FR235222

L. Gomez‐Paloma, S. Khochbin, S. Terracciano, 2007, ChemMedChem.

Testis-specific histone H3 expression in somatic cells.

C. Caron, S. Khochbin, S. Rousseaux, 2005, Trends in biochemical sciences.

Chromatin Structure: Composition and Function During Spermiogenesis

S. Khochbin, W. S. Ward, W. Ward, 2014 .

The Role of Bromodomain Testis-Specific Factor, BRDT, in Cancer: A Biomarker and A Possible Therapeutic Target

Florent Chuffart, S. Khochbin, S. Rousseaux, 2017, Cell journal.

Genome-wide mapping of histone H4 serine-1 phosphorylation during sporulation in Saccharomyces cerevisiae

Jonathan Schug, J. Schug, S. Berger, 2010, Nucleic acids research.

Marginal band microtubules are acetylated by αTAT1

S. Khochbin, T. Buchou, Ekaterina Bourova-Flin, 2020, Platelets.

Oncogenesis by Unprogrammed Gene Activation: A Critical Evaluation of Cancer Testis Genes

S. Khochbin, S. Rousseaux, J. Mi, 2014 .

Thoracic NUT carcinoma: Common pathological features despite diversity of clinical presentations.

G. Ferretti, S. Lantuejoul, S. Khochbin, 2021, Lung cancer.

Reprogramming Differentiation of NUT Midline Carcinoma by Epigenomic

J. Aster, J. Bradner, S. Sallan, 2011 .

Structural insights into the regulation of acetylation-dependent genome 1 condensation 2 3 4

M. Blackledge, Yingming Zhao, D. Panne, 2022 .

Aberrant activation of five embryonic stem cell-specific genes robustly predicts a high risk of relapse in breast cancers

Florent Chuffart, S. Khochbin, S. Rousseaux, 2023, BMC Genomics.

JCB: REPORT

A. Grichine, C. Chu, B. Day, 2009 .

Antisense RNA and p53 Regulation in Induced Murine Cell Differentiation

D. Grunwald, J. Lawrence, S. Khochbin, 1992, Annals of the New York Academy of Sciences.

Ectopic expression of a combination of 5 genes detects high risk forms of T-cell acute lymphoblastic leukemia

Yuan-fang Liu, M. Geng, Florent Chuffart, 2022, BMC Genomics.

Parp2 is required for the differentiation of post-meiotic germ cells: identification of a spermatid-specific complex containing Parp1, Parp2, TP2 and HSPA2.

M. Mark, V. Schreiber, S. Khochbin, 2009, Experimental cell research.

Pericentric heterochromatin reprogramming by new histone variants during mouse spermiogenesis

J. Garin, J. Thevenon, L. Kuhn, 2007, The Journal of cell biology.

Long-term intermittent hypoxia in mice induces inflammatory pathways implicated in sleep apnea and steatohepatitis in humans

R. Tamisier, Florent Chuffart, S. Khochbin, 2024, iScience.

Receptor-Independent Ectopic Activity of Prolactin Predicts Aggressive Lung Tumors and Indicates HDACi-Based Therapeutic Strategies.

A. de Reyniès, S. Khochbin, A. Debernardi, 2015, Antioxidants & redox signaling.

Histone variants and sensing of chromatin functional states

S. Khochbin, J. Govin, 2013, Nucleus.

Research Highlights: Highlights from the latest articles in epigenomics

S. Khochbin, S. Rousseaux, H. Shiota, 2013 .

Transgenerational inheritance of chromatin states.

S. Khochbin, S. Rousseaux, H. Shiota, 2013, Epigenomics.

Effects of downregulated HDAC6 expression on the proliferation of lung cancer cells.

S. Horinouchi, T. Yao, Minoru Yoshida, 2008, Biochemical and biophysical research communications.

Histone crotonylation specifically marks the haploid male germ cell gene expression program

Yingming Zhao, S. Khochbin, Emilie Montellier, 2012, BioEssays : news and reviews in molecular, cellular and developmental biology.

In the heart of a dynamic chromatin.

S. Khochbin, 2011, Chemistry & biology.

Molecular models for post-meiotic male genome reprogramming

S. Khochbin, Emilie Montellier, N. Reynoird, 2011, Systems biology in reproductive medicine.

Proteomic strategy for the identification of critical actors in reorganization of the post-meiotic male genome.

J. Garin, M. Ferro, S. Khochbin, 2012, Molecular human reproduction.

Differentiation of NUT midline carcinoma by epigenomic reprogramming.

J. Aster, J. Bradner, S. Sallan, 2011, Cancer research.

The RNA-binding protein Mex3b regulates the spatial organization of the Rap1 pathway

D. Nègre, Julien Courchet, D. Segretain, 2014, Development.

Amphiregulin promotes resistance to gefitinib in nonsmall cell lung cancer cells by regulating Ku70 acetylation.

L. Sancey, J. Coll, V. Josserand, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

Supplementary Information Structure of p300 in complex with Acyl-CoA variants

Yingming Zhao, E. Ortega, D. Panne, 2016 .

Histone variants: essential actors in male genome programming.

S. Khochbin, S. Rousseaux, Sophie Barral, 2018, Journal of biochemistry.