D. Clewell

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Enterococcus faecalis sex pheromone plasmid pAM373: analyses of TraA and evidence for its interaction with RpoB.

Y. Ozawa, E. D. De Boever, D. Clewell, 2005, Plasmid.

Conjugation and Genetic Exchange in Enterococci

G. Dunny, D. Clewell, 2002 .

Regulation of the pAD1-encoded sex pheromone response in Enterococcus faecalis: expression of the positive regulator TraE1

D. Clewell, K. Tanimoto, 1993, Journal of bacteriology.

Unconstrained bacterial promiscuity: the Tn916-Tn1545 family of conjugative transposons.

D. Clewell, S. Flannagan, D. D. Jaworski, 1995, Trends in microbiology.

PCR Fragment Length Polymorphism Analysis of Vancomycin-Resistant Enterococcus faecium

B. Robinson-Dunn, M. Zervos, J. Chow, 2000, Journal of Clinical Microbiology.

Molecular Analysis of Glycopeptide-ResistantEnterococcus faecium Isolates Collected from Michigan Hospitals over a 6-Year Period

Don B. Clewell, Marcus J. Zervos, B. Robinson-Dunn, 1998, Journal of Clinical Microbiology.

Characterization of Three Plasmid Deoxyribonucleic Acid Molecules in a Strain of Streptococcus faecalis: Identification of a Plasmid Determining Erythromycin Resistance

G. Dunny, D. Clewell, Y. Yagi, 1974, Journal of bacteriology.

Properties of erythromycin-inducible transposon Tn917 in Streptococcus faecalis

D. Clewell, P. Tomich, F. An, 1980, Journal of bacteriology.

Mapping of Streptococcus faecalis plasmids pAD1 and pAD2 and studies relating to transposition of Tn917

D. Clewell, P. Tomich, F. An, 1982, Journal of bacteriology.

Modification of Streptococcus faecalis sex pheromones after acquisition of plasmid DNA.

B. White, R. Craig, D. Clewell, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Streptococcus faecalis sex pheromone (cAM373) also produced by Staphylococcus aureus and identification of a conjugative transposon (Tn918)

B. White, D. Clewell, F. An, 1985, Journal of bacteriology.

A functional origin of transfer (oriT) on the conjugative transposon Tn916

D. Clewell, D. D. Jaworski, Anddon B. Clewell, 1995, Journal of bacteriology.

D. Clewell, S. Flannagan, C. Sedgley, 2011, Probiotics and antimicrobial proteins.

The enterococci : pathogenesis, molecular biology, and antibiotic resistance

M. Gilmore, D. Clewell, 2002 .

Quantitative real-time PCR detection of oral Enterococcus faecalis in humans.

D. Clewell, C. Sedgley, C. Shelburne, 2005, Archives of oral biology.

Effect of Growth Conditions on the Formation of the Relaxation Complex of Supercoiled ColE1 Deoxyribonucleic Acid and Protein in Escherichia coli

D. Helinski, D. Clewell, 1972, Journal of bacteriology.

Evidence for a chromosome-borne resistance transposon (Tn916) in Streptococcus faecalis that is capable of "conjugal" transfer in the absence of a conjugative plasmid

D. Clewell, A. Franke, Arthur E. FRANKEt, 1981, Journal of bacteriology.

Identification of a gene, rgg, which regulates expression of glucosyltransferase and influences the Spp phenotype of Streptococcus gordonii Challis

D. Clewell, M. Sulavik, G. Tardif, 1992, Journal of bacteriology.

Rgg is a positive transcriptional regulator of the Streptococcus gordonii gtfG gene

D. Clewell, M. Sulavik, 1996, Journal of bacteriology.

Identification and Characterization of a Determinant (eep) on the Enterococcus faecalisChromosome That Is Involved in Production of the Peptide Sex Pheromone cAD1

D. Clewell, F. An, M. Sulavik, 1999, Journal of bacteriology.

Enterococcal sex pheromone precursors are part of signal sequences for surface lipoproteins

G. Dunny, D. Clewell, S. Flannagan, 2000, Molecular microbiology.

Analysis of plasmid deoxyribonucleic acid in a cariogenic strain of Streptococcus faecalis: an approach to identifying genetic determinants on cryptic plasmids

D. Clewell, D. R. Oliver, B. L. Brown, 1977, Journal of bacteriology.

Plasmid-determined tetracycline resistance in Streptococcus faecalis: tandemly repeated resistance determinants in amplified forms of pAMalpha1 DNA.

D. Clewell, Y. Yagi, 1976, Journal of molecular biology.

Transmissible toxin (hemolysin) plasmid in Streptococcus faecalis and its mobilization of a noninfectious drug resistance plasmid

G. Dunny, D. Clewell, 1975, Journal of bacteriology.

A New High-Level Gentamicin Resistance Gene,aph(2")-Id, in Enterococcus spp

M. Zervos, J. Chow, D. Clewell, 1998, Antimicrobial Agents and Chemotherapy.

Characterization of a Small Plasmid Determining Resistance to Erythromycin, Lincomycin, and Vernamycin Bα in a Strain of Streptococcus sanguis Isolated from Dental Plaque

D. Clewell, Y. Yagi, W. Frez, 1978, Antimicrobial Agents and Chemotherapy.

Plasmid-Determined Resistance to Erythromycin: Comparison of Strains of Streptococcus faecalis and Streptococcus pyogenes with Regard to Plasmid Homology and Resistance Inducibility

D. Clewell, Y. Yagi, A. Franke, 1975, Antimicrobial Agents and Chemotherapy.

Identification of the cAD1 Sex Pheromone Precursor in Enterococcus faecalis

D. Clewell, F. An, 2002, Journal of bacteriology.

Nucleotide sequence of the 18-kb conjugative transposon Tn916 from Enterococcus faecalis.

Y. Su, D. Clewell, S. Flannagan, 1994, Plasmid.

Highly efficient protoplast transformation system for Streptococcus faecalis and a new Escherichia coli-S. faecalis shuttle vector

R. Wirth, D. Clewell, F. An, 1986, Journal of bacteriology.

The Conjugative Transposons of Gram-Positive Bacteria

D. Clewell, S. Flannagan, 1993 .

Completion of the nucleotide sequence of the Enterococcus faecalis conjugative virulence plasmid pAD1 and identification of a second transfer origin.

R. Wirth, M. Gilmore, K. Weaver, 2001, Plasmid.

Identification and partial purification of a dipeptidyl aminopeptidase from Streptococcus faecalis.

B. White, D. Clewell, 1986, Journal of general microbiology.

Evidence for conjugal transfer of a Streptococcus faecalis transposon (Tn916) from a chromosomal site in the absence of plasmid DNA.

D. Clewell, A. Franke, 1981, Cold Spring Harbor symposia on quantitative biology.

Conjugative transfer of Tn916 in Enterococcus faecalis: trans activation of homologous transposons

D. Clewell, S. Flannagan, 1991, Journal of bacteriology.

Conjugative transposons and the dissemination of antibiotic resistance in streptococci.

D. Clewell, C. Gawron-Burke, 1986, Annual review of microbiology.

A transposon in Streptococcus faecalis with fertility properties

D. Clewell, C. Gawron-Burke, 1982, Nature.

High incidence of hemolysin production by Enterococcus (Streptococcus) faecalis strains associated with human parenteral infections

D. Clewell, Y. Ike, H. Hashimoto, 1987, Journal of clinical microbiology.

Generation of Tn5 insertions in streptococcal conjugative transposon Tn916

M. Yamamoto, D. Clewell, C. Gawron-Burke, 1987, Applied and environmental microbiology.

Spontaneous switching of the sucrose-promoted colony phenotype in Streptococcus sanguis

D. Clewell, G. Jones, M. Sulavik, 1989, Infection and immunity.

Enterococci Are Gram-positive Cocci That Prevalence, Phenotype and Genotype of Oral Enterococci

D. Clewell, C. Sedgley, S. Lennan, 2022 .

Phase variation of Enterococcus faecalis pAD1 conjugation functions relates to changes in iteron sequence region

K. Weaver, D. Clewell, F. An, 1995, Journal of bacteriology.

Characterization of an Active Partition System for the Enterococcus faecalis Pheromone-Responding Plasmid pAD1

K. Weaver, D. Clewell, M. Francia, 2007, Journal of bacteriology.

Replication of Enterococcus faecalis Pheromone-Responding Plasmid pAD1: Location of the Minimal Replicon and oriV Site and RepA Involvement in Initiation of Replication

K. Weaver, D. Clewell, M. Francia, 2004, Journal of bacteriology.

Evidence that the hemolysin/bacteriocin phenotype of Enterococcus faecalis subsp. zymogenes can be determined by plasmids in different incompatibility groups as well as by the chromosome

D. Clewell, Y. Ike, 1992, Journal of bacteriology.

Molecular analysis of Streptococcus gordonii glucosyltransferase phase variants.

D. Clewell, M. Vickerman, M. Sulavik, 1995, Developments in biological standardization.

Ecological implications of glucosyltransferase phase variation in Streptococcus gordonii

D. Clewell, M. Vickerman, G. Jones, 1991, Applied and environmental microbiology.

Amino acid sequence of pheromone‐inducible surface protein in Enterococcus faecalis, that is encoded on the conjugative plasmid pPD1

H. Nagasawa, J. Nakayama, D. Clewell, 1990, FEBS letters.

Construction of recombination-deficient strains of Streptococcus gordonii by disruption of the recA gene

D. Clewell, M. Vickerman, D. Heath, 1993, Journal of bacteriology.

Recombination-deficient mutant of Streptococcus faecalis

D. Clewell, Y. Yagi, 1980, Journal of bacteriology.

Regulation of the pAD1 sex pheromone response in Enterococcus faecalis: construction and characterization of lacZ transcriptional fusions in a key control region of the plasmid

K. Weaver, D. Clewell, 1988, Journal of bacteriology.

Hemolysin of Streptococcus faecalis subspecies zymogenes contributes to virulence in mice

D. Clewell, Y. Ike, H. Hashimoto, 1984, Infection and immunity.

Genetic organization of the bacterial conjugative transposon Tn916

M. Yamamoto, D. Clewell, C. Gawron-Burke, 1988, Journal of bacteriology.

Infectivity of a glucan synthesis-defective mutant of Streptococcus gordonii (Challis) in a rat endocarditis model.

C. Munro, D. Clewell, M. Sulavik, 1993, FEMS microbiology letters.

Evidence that coupling sequences play a frequency-determining role in conjugative transposition of Tn916 in Enterococcus faecalis

D. Clewell, D. D. Jaworski, Don B. CLEWELLl, 1994, Journal of bacteriology.

Hyperhemolytic phenomena associated with insertions of Tn916 into the hemolysin determinant of Enterococcus faecalis plasmid pAD1

D. Clewell, S. Flannagan, Y. Ike, 1992, Journal of bacteriology.

Multiple phase variation in haemolytic, adhesive and antigenic properties of Streptococcus gordonii.

D. Clewell, M. Vickerman, G. Jones, 1996, Microbiology.

Characterization of the left 4 kb of conjugative transposon Tn916: determinants involved in excision.

Y. Su, D. Clewell, Yan A. Su, 1993, Plasmid.

Buoyant densities of DNA from various strains of Streptococcus mutans.

G. Dunny, D. Clewell, T. Hausner, 1972, Archives of oral biology.

Isolation of supercoiled colicinogenic factor E 1 DNA sensitive to ribonuclease and alkali.

D. Sherratt, D. Helinski, D. Blair, 1972, Proceedings of the National Academy of Sciences of the United States of America.

Return of Streptococcus faecalis DNA cloned in Escherichia coli to its original host via transformation of Streptococcus sanguis followed by conjugative mobilization

M. Smith, D. Clewell, Michael D. SMITHt, 1984, Journal of bacteriology.

[Sex pheromones and plasmid transfer in Streptococcus faecalis].

B. White, D. Clewell, Y. Ike, 1985, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme.

The conjugative transposon Tn916 of Enterococcus faecalis: structural analysis and some key factors involved in movement.

Y. Su, D. Clewell, S. Flannagan, 1995, Developments in biological standardization.

Deletions in the carboxyl-terminal region of Streptococcus gordonii glucosyltransferase affect cell-associated enzyme activity and sucrose-associated accumulation of growing cells

D. Clewell, M. Vickerman, 1997, Applied and environmental microbiology.

Oral streptococci with genetic determinants similar to the glucosyltransferase regulatory gene, rgg

D. Clewell, M. Vickerman, M. Sulavik, 1995, Infection and immunity.

Degenerate oligonucleotide primers for enzymatic amplification of recA sequences from gram-positive bacteria and mycoplasmas

K. Dybvig, D. Clewell, S. Hollingshead, 1992, Journal of bacteriology.

Plasmid-determined tetracycline resistance in Streptococcus faecalis: evidence for gene amplification during growth in presence of tetracycline.

D. Clewell, Y. Yagi, B. Bauer, 1975, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of the determinant (traB) encoding sex pheromone shutdown by the hemolysin/bacteriocin plasmid pAD1 in Enterococcus faecalis.

D. Clewell, F. An, 1994, Plasmid.

Glucosyltransferase phase variation in Streptococcus gordonii tnodifies adhesion to saliva-coated hydroxyapatite surfaces in a siicrose-itidependctit tnanner

D. Clewell, G. Jones, '. M.M.Vickerman, 2005 .

Glucosyltransferase phase variation in Streptococcus gordonii modifies adhesion to saliva-coated hydroxyapatite surfaces in a sucrose-independent manner.

D. Clewell, M. Vickerman, G. Jones, 1992, Oral microbiology and immunology.

Sucrose-promoted accumulation of growing glucosyltransferase variants of Streptococcus gordonii on hydroxyapatite surfaces

D. Clewell, M. Vickerman, G. Jones, 1991, Infection and immunity.

Plasmid transfer in Streptococcus faecalis: production of multiple sex pheromones by recipients.

R. Craig, G. Dunny, D. Clewell, 1979, Plasmid.

Identification, characterization, and nucleotide sequence of a region of Enterococcus faecalis pheromone-responsive plasmid pAD1 capable of autonomous replication

K. Weaver, D. Clewell, F. An, 1993, Journal of bacteriology.

Sex Pheromones and the Plasmid-Encoded Mating Response in Enterococcus faecalis

D. Clewell, 1993 .

Identification and characterization of a small sequence located at two sites on the amplifiable tetracycline resistance plasmid pAMalpha1 in Streptococcus faecalis

D. Clewell, Y. Yagi, 1977, Journal of bacteriology.

In vitro susceptibility and molecular analysis of gentamicin-resistant enterococci.

M. Zervos, J. Chow, D. Clewell, 1998, Diagnostic microbiology and infectious disease.

Isolation and Characterization of Plasmid Deoxyribonucleic Acid from Streptococcus mutans

G. Dunny, D. Clewell, N. Birch, 1973, Journal of bacteriology.

Direct inhibition of Col E 1 plasmid DNA replication in Escherichia coli by rifampicin.

D. Clewell, J. Cranston, B. Evenchik, 1972, Nature: New biology.

Chairmen’s Introduction: Plasmid Transfer

D. Clewell, N. Willetts, 1985 .

Plasmids, drug resistance, and gene transfer in the genus Streptococcus.

D. Clewell, 1981, Microbiological reviews.

D. Clewell, P. Tomich, F. An, 1979, Antimicrobial Agents and Chemotherapy.

Characterization of a Plasmid Determining Resistance to Erythromycin, Lincomycin, and Vernamycin Bα in a Strain of Streptococcus pyogenes

D. Clewell, A. Franke, Don B. Clewell, 1974, Antimicrobial Agents and Chemotherapy.

Supercoiled circular DNA-protein complex in Escherichia coli: purification and induced conversion to an opern circular DNA form.

D. Helinski, D. Clewell, 1969, Proceedings of the National Academy of Sciences of the United States of America.

Nature of Col E1 Plasmid Replication in Escherichia coli in the Presence of Chloramphenicol

D. Clewell, D B Clewell, 1972, Journal of bacteriology.

Detection of the High-Level Aminoglycoside Resistance Gene aph(2")-Ib in Enterococcus faecium

M. Zervos, J. Chow, D. Clewell, 2000, Antimicrobial Agents and Chemotherapy.

Molecular characterization of highly gentamicin-resistant Enterococcus faecalis isolates lacking high-level streptomycin resistance

M. Zervos, J. Chow, D. Clewell, 1993, Antimicrobial Agents and Chemotherapy.

Prevalence, phenotype and genotype of oral enterococci.

D. Clewell, D B Clewell, C M Sedgley, 2004, Oral microbiology and immunology.

Genetic analysis of the pAD1 hemolysin/bacteriocin determinant in Enterococcus faecalis: Tn917 insertional mutagenesis and cloning

M. Gilmore, D. Clewell, Y. Ike, 1990, Journal of bacteriology.

Genetic Analysis of a High-Level Vancomycin-Resistant Isolate of Staphylococcus aureus

J. Shetty, S. Gill, F. Tenover, 2003, Science.

Simple and Reliable Multiplex PCR Assay for Surveillance Isolates of Vancomycin-Resistant Enterococci

H. Kumon, J. Chow, D. Clewell, 2000, Journal of Clinical Microbiology.

Nucleotide sequence of the gelatinase gene (gelE) from Enterococcus faecalis subsp. liquefaciens

Y. Su, R. Wirth, D. Clewell, 1991, Infection and immunity.

Bacterial sex pheromone-induced plasmid transfer

Don B. Clewell, D. Clewell, 1993, Cell.

Properties of Enterococcus faecalis plasmid pAD1, a member of a widely disseminated family of pheromone-responding, conjugative, virulence elements encoding cytolysin.

D. Clewell, 2007, Plasmid.

Complete nucleotide sequence of macrolide-lincosamide-streptogramin B-resistance transposon Tn917 in Streptococcus faecalis

D. Clewell, J. H. Shaw, J. H. Shaw, 1985, Journal of bacteriology.

Bacterial Conjugation

D. Clewell, Peter T. Barth, M. Brian, 1993, Springer US.

Genetic structure of the Enterococcus faecalis plasmid pAD1-encoded cytolytic toxin system and its relationship to lantibiotic determinants

M. Gilmore, P. Charles, D. Clewell, 1994, Journal of bacteriology.

Aminoglycoside Resistance Genesaph(2")-Ib and aac(6′)-Im Detected Together in Strains of both Escherichia coli andEnterococcus faecium

J. Chow, D. Clewell, S. Lerner, 2001, Antimicrobial Agents and Chemotherapy.

A Genetic Determinant in Streptococcus gordonii Challis Encodes a Peptide with Activity Similar to That of Enterococcal Sex Pheromone cAM373, Which Facilitates Intergeneric DNA Transfer

D. Clewell, S. Flannagan, M. Vickerman, 2010, Journal of bacteriology.

Properties of a supercoiled deoxyribonucleic acid-protein relaxation complex and strand specificity of the relaxation event.

D. Helinski, D. Clewell, D R Helinski, 1970, Biochemistry.

Induced cell aggregation and mating in Streptococcus faecalis: evidence for a bacterial sex pheromone.

G. Dunny, D. Clewell, B. L. Brown, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Plasmids, drug resistance, and gene transfer in the genus Streptococcus

D. Clewell, 1981 .

Mutations in the aph(2")-Ic Gene Are Responsible for Increased Levels of Aminoglycoside Resistance

J. Chow, S. Vakulenko, D. Clewell, 2002, Antimicrobial Agents and Chemotherapy.

Bacterial plasmids in the oral and endodontic microflora

D. Clewell, C. Sedgley, 2004 .

Conjugation and Resistance Transfer in Streptococci and Other Gram Positive Species: Plasmids, Sex Pheromones and “Conjugative Transposons” (A Review)

D. Clewell, 1981 .

Effects of rifampicin, streptolydigin and actinomycin D on the replication of Col E1 plasmid DNA in Escherichia coli.

D. Clewell, B. Evenchik, 1973, Journal of molecular biology.

Conjugative transfer of R-plasmids from Streptococcus faecalis to Staphylococcus aureus

D. Clewell, D. Schaberg, L. Glatzer, 1982, Antimicrobial Agents and Chemotherapy.

Regulation of the pAD1 sex pheromone response of Enterococcus faecalis by direct interaction between the cAD1 peptide mating signal and the negatively regulating, DNA-binding TraA protein.

D. Clewell, S. Fujimoto, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Construction of Enterococcus faecalis pAD1 miniplasmids: identification of a minimal pheromone response regulatory region and evaluation of a novel pheromone-dependent growth inhibition.

K. Weaver, D. Clewell, 1989, Plasmid.

Plasmid-associated hemolysin and aggregation substance production contribute to virulence in experimental enterococcal endocarditis

M. Zervos, J. Chow, D. Clewell, 1993, Antimicrobial Agents and Chemotherapy.

Purification and substrate specificity of a strongly hydrophobic extracellular metalloendopeptidase ("gelatinase") from Streptococcus faecalis (strain 0G1-10).

D. Clewell, F. An, K. Mäkinen, 1989, The Journal of biological chemistry.

Enterococcal plasmid transfer: sex pheromones, transfer origins, relaxases, and the Staphylococcus aureus issue.

D. Clewell, M. Francia, S. Flannagan, 2002, Plasmid.

Amplification of the Tetracycline Resistance Determinant of pAMα1 in Enterococcus faecalis Requires a Site-Specific Recombination Event Involving Relaxase

D. Clewell, M. Francia, 2002, Journal of bacteriology.

Transfer origins in the conjugative Enterococcus faecalis plasmids pAD1 and pAM373: identification of the pAD1 nic site, a specific relaxase and a possible TraG‐like protein

D. Clewell, M. Francia, 2002, Molecular microbiology.

Plasmid Content of a Vancomycin-Resistant Enterococcus faecalis Isolate from a Patient Also Colonized by Staphylococcus aureus with a VanA Phenotype

M. Zervos, J. Chow, Y. Ozawa, 2003, Antimicrobial Agents and Chemotherapy.

Vancomycin Resistance Plasmid in Enterococcus faecalis That Encodes Sensitivity to a Sex Pheromone Also Produced by Staphylococcus aureus

E. D. De Boever, D. Clewell, S. Showsh, 2001, Antimicrobial Agents and Chemotherapy.

Possible Connection between a Widely Disseminated Conjugative Gentamicin Resistance (pMG1-Like) Plasmid and the Emergence of Vancomycin Resistance in Enterococcus faecium

D. Clewell, H. Tomita, Y. Ike, 2002, Journal of Clinical Microbiology.

Strand-specific supercoiled DNA-protein relaxation complexes: comparison of the complexes of bacterial plasmids ColE1 and ColE2.

D. Helinski, D. Blair, D. Clewell, 1971, Proceedings of the National Academy of Sciences of the United States of America.

Regeneration of insertionally inactivated streptococcal DNA fragments after excision of transposon Tn916 in Escherichia coli: strategy for targeting and cloning of genes from gram-positive bacteria

D. Clewell, C. Gawron-Burke, 1984, Journal of bacteriology.

Sex pheromones and plasmid transfer in Enterococcus faecalis.

K. Weaver, D. Clewell, D B Clewell, 1989, Plasmid.

Identification and characterization of genes encoding sex pheromone cAM373 activity in Enterococcus faecalis and Staphylococcus aureus

D. Clewell, S. Flannagan, 2002, Molecular microbiology.

Identification and characterization of genes encoding sex pheromone cAM 373 activity in Enterococcus faecalis and Staphylococcus aureus

D. Clewell, S. Flannagan, 2002 .

Nucleotide sequence analysis of the Streptococcus gordonii glucosyltransferase gene, gtfG.

D. Clewell, M. Vickerman, G. Jones, 1997, DNA sequence : the journal of DNA sequencing and mapping.

Changes in the carboxyl-terminal repeat region affect extracellular activity and glucan products of Streptococcus gordonii glucosyltransferase

D. Clewell, M. Vickerman, M. Sulavik, 1996, Infection and immunity.

Novel shuttle plasmid vehicles for Escherichia-Streptococcus transgeneric cloning.

R. P. Evans, K. R. Jones, D. Clewell, 1983, Gene.

A cloning vector able to replicate in Escherichia coli and Streptococcus sanguis.

R. P. Evans, K. R. Jones, D. Clewell, 1982, Gene.

Regulates Expression of Glucosyltransferase and Influences the Spp Phenotype of Streptococcus

D. Clewell, M. Sulavik, G. Tardif, 2022 .

Electron microscopic mapping of deletions on a streptococcal plasmid carrying extraordinarily long inverted repeats.

D. Clewell, P. Tomich, D. Behnke, 1980, Plasmid.

Structure and Evolution

David A. Jackson, Don B. Clewell, Stanley N Cohen, 1985 .

Characterization of the tet(M) determinant of Tn916: evidence for regulation by transcription attenuation

Y. Su, D. Clewell, P. He, 1992, Antimicrobial Agents and Chemotherapy.

Existence of the colicinogenic factor-sex factor ColI-b-P9 as a supercoiled circular DNA-protein relaxation complex.

D. Helinski, D. Clewell, D. Helinski, 1970, Biochemical and biophysical research communications.

Targeted disruption of the PD 78 gene ( truF ) reduces pheromone-inducible conjugal transfer of the bacteriocin plasmid pPD 1 in Enterococcus faecalis

J. Nakayama, D. Clewell, A. a, 2003 .

Targeted disruption of the PD78 gene (traF) reduces pheromone-inducible conjugal transfer of the bacteriocin plasmid pPD1 in Enterococcus faecalis.

J. Nakayama, D. Clewell, A. Suzuki, 1995, FEMS microbiology letters.

Transfer functions of the Streptococcus faecalis plasmid pAD1: organization of plasmid DNA encoding response to sex pheromone

E. Ehrenfeld, D. Clewell, 1987, Journal of bacteriology.

Identification of pheromone-induced surface proteins in Streptococcus faecalis and evidence of a role for lipoteichoic acid in formation of mating aggregates

E. Ehrenfeld, D. Clewell, R. Kessler, 1986, Journal of bacteriology.

Sex pheromones and plasmid transfer in Streptococcus faecalis: a pheromone, cAM373, which is also excreted by Staphylococcus aureus.

B. White, D. Clewell, F. An, 1985, Basic life sciences.

Genetic analysis of the pAD1 pheromone response in Streptococcus faecalis, using transposon Tn917 as an insertional mutagen

D. Clewell, Y. Ike, 1984, Journal of bacteriology.

Genetic Analysis ofthepAD1Pheromone Response in Streptococcus faecalis, UsingTransposon Tn917as an Insertional Mutagen

D. Clewell, 1984 .

Plasmid content of Streptococcus faecalis strain 39-5 and identification of a pheromone (cPD1)-induced surface antigen.

D. Clewell, Y. Yagi, D. Lopatin, 1983, Journal of general microbiology.

A novel gentamicin resistance gene in Enterococcus

S. Tsai, M. Zervos, J. Chow, 1997, Antimicrobial agents and chemotherapy.

Enterococcus faecalis pheromone-responding plasmid pAD1 gives rise to an aggregation (clumping) response when cells are exposed to subinhibitory concentrations of chloramphenicol, erythromycin, or tetracycline.

K. Wu, D. Clewell, F. An, 1999, Plasmid.

Sequence analysis of termini of conjugative transposon Tn916

D. Clewell, S. Flannagan, Y. Ike, 1988, Journal of bacteriology.

Virulence, phenotype and genotype characteristics of endodontic Enterococcus spp.

D. Clewell, S. Flannagan, G. Dahlén, 2005, Oral microbiology and immunology.

Characterization ofaSmallPlasmid Determining Resistance toErythromycin, Lincomycin, andVernamycin BainaStrain ofStreptococcus sanguis Isolated fromDental Plaque

D. Clewell, 1978 .

Plasmids and pheromone response of the beta-lactamase producer Streptococcus (Enterococcus) faecalis HH22

D. Clewell, B. Murray, F. An, 1988, Antimicrobial Agents and Chemotherapy.

Indication of Transposition of a Mobile DNA Element Containing the vat(D) and erm(B) Genes inEnterococcus faecium

L. Jensen, D. Clewell, S. Flannagan, 2001, Antimicrobial Agents and Chemotherapy.

Movable genetic elements and antibiotic resistance in enterococci

D. Clewell, 1990, European Journal of Clinical Microbiology and Infectious Diseases.

Characterization of a class of nonformylated Enterococcus faecalis-derived neutrophil chemotactic peptides: the sex pheromones.

W. Marasco, R. Craig, M. Fujino, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of the traC determinant of the Enterococcus faecalis hemolysin-bacteriocin plasmid pAD1: binding of sex pheromone

D. Clewell, K. Tanimoto, F. An, 1993, Journal of bacteriology.

Regulation of the pAD1 sex pheromone response in Enterococcus faecalis: effects of host strain and traA, traB, and C region mutants on expression of an E region pheromone-inducible lacZ fusion

K. Weaver, D. Clewell, 1990, Journal of bacteriology.

A pAD1-Encoded Small RNA Molecule, mD, Negatively Regulates Enterococcus faecalis Pheromone Response by Enhancing Transcription Termination

D. Clewell, H. Tomita, 2000, Journal of bacteriology.

Regulation of the pAD1-encoded sex pheromone response in Enterococcus faecalis: nucleotide sequence analysis of traA

D. Clewell, L. Pontius, 1992, Journal of bacteriology.

Regulation of transfer of the Enterococcus faecalis pheromone-responding plasmid pAD1: temperature-sensitive transfer mutants and identification of a new regulatory determinant, traD

D. Clewell, K. Tanimoto, M. D. C. de Freire Bastos, 1997, Journal of bacteriology.

Enterococcus faecalis conjugative plasmid pAM373: complete nucleotide sequence and genetic analyses of sex pheromone response

C. Fraser, E. D. De Boever, D. Clewell, 2000, Molecular microbiology.

Conjugative transfer of Enterococcus faecalis plasmid pAD1: nucleotide sequence and transcriptional fusion analysis of a region involved in positive regulation

D. Clewell, L. Pontius, 1992, Journal of bacteriology.

Nucleotide sequence of the sex pheromone inhibitor (iAD1) determinant of Enterococcus faecalis conjugative plasmid pAD1.

J. Nakayama, D. Clewell, A. Suzuki, 1990, Plasmid.

Isolation and structure of the sex pheromone inhibitor, iPD1, excreted by Streptococcus faecalis donor strains harboring plasmid pPD1

Y. Sakagami, C. Kitada, M. Fujino, 1987, Journal of Bacteriology.

Streptococcus faecalis sex pheromone (cAD1) response: evidence that the peptide inhibitor excreted by pAD1-containing cells may be plasmid determined.

D. Clewell, A. Suzuki, Y. Ike, 1987, Plasmid.

Isolation and Structure of the Streptococcus faecalis Sex Pheromone Inhibitor, iAD1, That Is Excreted by the Donor Strain Harboring Plasmid pAD1

Y. Sakagami, C. Kitada, M. Fujino, 1986 .

Broad geographical distribution of a cytotoxin gene mediating beta-hemolysis and bacteriocin activity among Streptococcus faecalis strains

D. Clewell, D. J. Leblanc, D. Behnke, 1983, Infection and immunity.

Sex pheromone cAD1 in Streptococcus faecalis: induction of a function related to plasmid transfer

D. Clewell, B. L. Brown, 1980, Journal of Bacteriology.

Cloning and characterization of a region of Enterococcus faecalis plasmid pPD1 encoding pheromone inhibitor (ipd), pheromone sensitivity (traC), and pheromone shutdown (traB) genes

K. Yoshida, J. Nakayama, D. Clewell, 1995, Journal of bacteriology.

A phase variation event that activates conjugation functions encoded by the Enterococcus faecalis plasmid pAD1.

D. Clewell, L. Pontius, 1991, Plasmid.

Control of Enterococcus faecalis sex pheromone cAD1 elaboration: effects of culture aeration and pAD1 plasmid-encoded determinants.

K. Weaver, D. Clewell, 1991, Plasmid.

The origin of transfer (oriT) of the enterococcal, pheromone-responding, cytolysin plasmid pAD1 is located within the repA determinant.

D. Clewell, F. An, 1997, Plasmid.

Quantitative analysis for pheromone inhibitor and pheromone shutdown in Enterococcus faecalis.

J. Nakayama, G. Dunny, D. Clewell, 1995, Developments in biological standardization.

Identification and Characterization of a Determinant ( eep ) on the Enterococcus faecalis Chromosome That Is Involved in Production of the Peptide Sex Pheromone cAD 1

D. Clewell, M. Sulavik, AN FLORENCEY., 1999 .

Conjugative Transfer ofEnterococcus faecalis Plasmid pADi: Nucleotide Sequence andTranscriptional Fusion Analysis ofaRegion Involved inPositive Regulation

D. Clewell, 1992 .

Characterization of plasmids determining hemolysin and bacteriocin production in Streptococcus faecalis 5952

D. Clewell, D. R. Oliver, B. L. Brown, 1977, Journal of bacteriology.

Isolation and structure of bacterial sex pheromone, cPD1.

R. Craig, Y. Sakagami, C. Kitada, 1984, Science.

Isolation and structure of the Streptococcus faecalis sex pheromone, cAM373

B. White, Y. Sakagami, C. Kitada, 1986, FEBS letters.

The Enterococcus faecalis pheromone-responsive plasmid pAM373 does not encode an entry exclusion function.

E. D. De Boever, D. Clewell, 2001, Plasmid.

A transposon (Tn917) in Streptococcus faecalis that exhibits enhanced transposition during induction of drug resistance.

D. Clewell, P. Tomich, F. An, 1979, Cold Spring Harbor symposia on quantitative biology.

Catalytic domain of plasmid pAD1 relaxase TraX defines a group of relaxases related to restriction endonucleases

F. de la Cruz, G. Moncalián, D. Clewell, 2013, Proceedings of the National Academy of Sciences.

The catalytic domain of plasmid pAD 1 relaxase TraX defines a novel group of relaxases related to restriction endonucleases

D. Clewell, M. Francia, F. Cruz, 2013 .

Transfer Functions oftheStreptococcus faecalis Plasmid pADl: Organization ofPlasmid DNA Encoding Response to SexPheromone

D. Clewell, Elizabeth E. EHRENFELDt, 1987 .

Tn917 transposase. Sequence correction reveals a single open reading frame corresponding to the tnpA determinant of Tn3-family elements.

D. Clewell, F. An, 1991, Plasmid.

Tales of conjugation and sex pheromones

D. Clewell, 2011, Mobile Genetic Elements.

Molecular analysis of representative Streptococcus gordonii Spp phase variants reveals no differences in the glucosyltransferase structural gene, gtfG.

D. Clewell, M. Vickerman, G. Jones, 1997, Oral microbiology and immunology.

Immunological Characterization of Pheromone-induced Proteins Associated with Sexual Aggregation in Enterococcus faecalis.

H. Nagasawa, J. Nakayama, D. Clewell, 1992, Bioscience, biotechnology, and biochemistry.

C-terminal identification of AD74, a proteolytic product of Enterococcus faecalis aggregation substance: application of liquid chromatography/mass spectrometry.

J. Nakayama, D. Clewell, A. Isogai, 1992, Bioscience, biotechnology, and biochemistry.

Prevention of x-ray-induced leukemia in mice. I. Action of a radiation leukemia protection factor in several mouse strains following leukemogenic or sublethal doses of x-ray.

M. Hodes, D. Clewell, J. Hubbard, 1966, Cancer research.

Fractionation of spleen and serum in attempts to isolate the radiation-leukemia protection factor.

M. Hodes, D. Clewell, L. Yip, 1969, Cancer research.

Conjugation in Gram-Positive Bacteria

D. Clewell, Clewell Db, M. Francia, 2004 .

A conjugative transposon (Tn919) in Streptococcus sanguis

D. Clewell, Gerald F. FITZGERALDt, 1985, Infection and immunity.

Effect ofGrowth Conditions on theFormation oftheRelaxation Complex ofSupercoiled ColEl Deoxyribonucleic AcidandProtein in Escherichia coli

D. Helinski, D. Clewell, 1972 .

Antimutagenesis and Anticarcinogenesis Mechanisms

A. Hollaender, D. Clewell, D. Shankel, 1986, Basic Life Sciences.

Amplification of the tetracycline resistance determinant of plasmid pAM alpha 1 in Streptococcus faecalis: dependence on host recombination machinery

D. Clewell, Y. Yagi, 1980, Journal of bacteriology.

Recombination Sequences and the Amplification of the Tetracycline-Resistance Determinant in Plasmid pAMα1 of Streptococcus Faecalis

D. Clewell, Y. Yagi, 1977 .

Tn924, a chromosome-borne transposon encoding high-level gentamicin resistance in Enterococcus faecalis

M. Zervos, J. Chow, D. Clewell, 1994, Antimicrobial Agents and Chemotherapy.