Jun Chen

发表

Discovery and Design of Novel HSP90 Inhibitors Using Multiple Fragment‐based Design Strategies

Jean M. Severin, P. Hajduk, J. R. Huth, 2007, Chemical biology & drug design.

Pentacyclic triterpenes. Part 3: Synthesis and biological evaluation of oleanolic acid derivatives as novel inhibitors of glycogen phosphorylase.

Luyong Zhang, Jun Chen, Jun O. Liu, 2006, Bioorganic & medicinal chemistry letters.

Discovery of a novel small molecule binding site of human survivin.

Jun Chen, Saul H Rosenberg, Kenneth M Comess, 2007, Bioorganic & medicinal chemistry letters.

ALARM NMR: a rapid and robust experimental method to detect reactive false positives in biochemical screens.

Renaldo Mendoza, Jun Chen, P. Hajduk, 2005, Journal of the American Chemical Society.

Discovery of N-[4-[6-tert-butyl-5-methoxy-8-(6-methoxy-2-oxo-1H-pyridin-3-yl)-3-quinolyl]phenyl]methanesulfonamide (RG7109), a potent inhibitor of the hepatitis C virus NS5B polymerase.

D. Davis, A. Railkar, Amy D. Fung, 2014, Journal of medicinal chemistry.

Molecular modelling studies of 3,5-dipyridyl-1,2,4-triazole derivatives as xanthine oxidoreductase inhibitors using 3D-QSAR, Topomer CoMFA, molecular docking and molecular dynamic simulations

Jun Chen, Jia-Huang Li, Hong-Jin Tang, 2016 .

Exploring the interaction between Salvia miltiorrhiza and xanthine oxidase: insights from computational analysis and experimental studies combined with enzyme channel blocking

L. Yang, Jun Chen, Jia-Huang Li, 2016 .

Synthesis and Antiproliferative Activity of New Thiosemicarboxamide Derivatives

Jun Chen, Yafei Guo, Hongyu Hu, 2021, Chemistry & biodiversity.

Synthesis and bioactivities of amino acid ester conjugates of phenazine-1-carboxylic acid.

Zhihong Xu, Jun Chen, Junfan Niu, 2016, Bioorganic & medicinal chemistry letters.

Design, synthesis and antifungal activities in vitro of novel tetralin compounds

Jun Chen, Youjun Zhou, Ju Zhu, 2008 .

Synthesis and biological evaluation of tanshinone IIA derivatives as novel endothelial protective agents.

Jun Chen, Kuojun Zhang, Jin-Xing Wang, 2017, Future medicinal chemistry.

Synthesis and antifungal activities of novel 2-aminotetralin derivatives.

Haitao Ji, Jun Chen, Yuan-Ying Jiang, 2007, Journal of medicinal chemistry.

Phenols and diketopiperazines isolated from Antarctic-derived fungi, Penicillium citreonigrum SP-6

Jun Chen, Qi-Hang Zou, Jia Huang, 2018, Phytochemistry Letters.

Synthesis and Biological Evaluation of Asiatic Acid Derivatives as Inhibitors of Glycogen Phosphorylases

Luyong Zhang, Jun Chen, Jun O. Liu, 2009, Chemistry & biodiversity.

Synthesis and evaluation of xanthine oxidase inhibitory and antioxidant activities of 2-arylbenzo[b]furan derivatives based on salvianolic acid C.

Jun Chen, Xiaowei Zhang, Hong-Jin Tang, 2016, European journal of medicinal chemistry.

Design and synthesis of adamantyl-substituted flavonoid derivatives as anti-inflammatory Nur77 modulators: Compound B7 targets Nur77 and improves LPS-induced inflammation in vitro and in vivo.

Zhanghua Wu, Boqun Li, Yuqing Qian, 2022, Bioorganic chemistry.

Design, synthesis and biological evaluation of novel xanthine oxidase inhibitors bearing a 2-arylbenzo[b]furan scaffold.

Jun Chen, Mei Zhou, Hong-Jin Tang, 2018, European journal of medicinal chemistry.

Pentacyclic Triterpenes. Part 3. Synthesis and Biological Evaluation of Oleanolic Acid Derivatives as Novel Inhibitors of Glycogen Phosphorylase.

Luyong Zhang, Jun Chen, Jun O. Liu, 2006 .

N-aryl-benzimidazolones as novel small molecule HSP90 inhibitors.

Jun Chen, Saul H Rosenberg, Xiaohong Song, 2010, Bioorganic & medicinal chemistry letters.

Triterpenoid saponins in roots of Achyranthese bidentata

Yan-jing Li, Jun Chen, L. Ping, 2012 .

Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.

Hualiang Jiang, Honglin Li, Hong Liu, 2011, European journal of medicinal chemistry.

Chemical constituents from the aerial parts of Codonopsis nervosa

Jun Chen, Hui-Jun Li, L. Ping, 2012 .

Synthesis and Biological Evaluation of Novel Pyrazolo[4,3‐b]oleanane Derivatives as Inhibitors of Glycogen Phosphorylase

Luyong Zhang, Jun Chen, Jun O. Liu, 2008, Chemistry & biodiversity.

Proteomic Analysis for Malonylastragaloside I in U937 Leukemia Cells by Modified Label-free Quantitative Strategy with LC Chip Q-TOF MS/MS

E-hu Liu, Jun Chen, Xiao-dong Wen, 2011 .