Miguel A. Prado

发表

Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins

S. Gygi, J. Paulo, Z. Modrušan, 2017, eLife.

Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals

Robert W. Williams, S. Gygi, J. Auwerx, 2017, The Journal of cell biology.

A TRAF 2 binding independent region of TNFR 2 is responsibl for TRAF 2 depletion and enhancement of cytotoxicity driven b TNFR 1

Miguel A. Prado, P. Casado, B. Darnay, 2014 .

An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons

Steven P. Gygi, Stephen J. Haggarty, Byung-Hoon Lee, 2017, The Journal of Biological Chemistry.

The Proteasome and Its Network: Engineering for Adaptability.

D. Finley, Miguel A. Prado, 2019, Cold Spring Harbor perspectives in biology.

Chromatin accessibility promotes hematopoietic and leukemia stem cell activity

Henry W. Long, C. T. Mowery, S. Gygi, 2020, Nature Communications.

Global proteomics of Ubqln2-based murine models of ALS

S. Gygi, J. Paulo, John Szpyt, 2020, bioRxiv.

Microtubule interfering agents and KSP inhibitors induce the phosphorylation of the nuclear protein p54(nrb), an event linked to G2/M arrest.

A. Burlingame, Miguel A. Prado, P. Casado, 2009, Journal of proteomics.

Characterization of HSP27 phosphorylation induced by microtubule interfering agents: implication of p38 signalling pathway.

C. Martínez-Campa, J. Iglesias, Miguel A. Prado, 2007, Archives of biochemistry and biophysics.

mTOR inhibitor-independent Autophagy Activator Ameliorates Tauopathy and Prionopathy Neurodegeneration Phenotypes

H. M. Petrassi, S. Lipton, S. Haggarty, 2022, bioRxiv.

Global proteome metastability response in isogenic animals to missense mutations and polyglutamine expansions in aging

S. Gygi, J. Paulo, R. Morimoto, 2022, bioRxiv.

Thiol-based direct threat sensing by the stress-activated protein kinase Hog1

S. Gygi, J. Paulo, D. Finley, 2019, Science Signaling.

Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice

Christopher R. Sibley, F. Villarroya, S. Gygi, 2022, Nature metabolism.

Structure‐Based Design of New KSP‐Eg5 Inhibitors Assisted by a Targeted Multicomponent Reaction

X. García‐Mera, J. Azuaje, E. Sotelo, 2014, Chembiochem : a European journal of chemical biology.

Altered patterns of global protein synthesis and translational fidelity in RPS15-mutated chronic lymphocytic leukemia.

S. Gygi, A. López-Guillermo, E. Campo, 2018, Blood.

USP14 deubiquitinates proteasome-bound substrates that are ubiquitinated at multiple sites

S. Gygi, Ying Lu, D. Finley, 2016, Nature.

ALS/FTD mutations in UBQLN2 impede autophagy by reducing autophagosome acidification through loss of function

R. Faull, C. Shaw, T. Siddique, 2020, Proceedings of the National Academy of Sciences.

Structures of chaperone-associated assembly intermediates reveal coordinated mechanisms of proteasome biogenesis

S. Gygi, J. Paulo, D. Finley, 2021, Nature Structural & Molecular Biology.

UBE2O remodels the proteome during terminal erythroid differentiation

M. Justice, S. Gygi, M. Fleming, 2017, Science.

Maternal Iron Deficiency Modulates Placental Transcriptome and Proteome in Mid-Gestation of Mouse Pregnancy.

M. Fleming, J. Paulo, D. Finley, 2021, The Journal of nutrition.

ALS/FTD mutations in UBQLN2 are linked to mitochondrial dysfunction through loss-of-function in mitochondrial protein import.

D. Finley, M. Monteiro, Miguel A. Prado, 2021, Human molecular genetics.

Membrane skeleton modulates erythroid proteome remodeling and organelle clearance.

S. Gygi, J. Paulo, D. Finley, 2020, Blood.

The deubiquitinating enzyme Usp14 controls ciliogenesis and Hedgehog signaling

D. Finley, M. Cesana, Byung-Hoon Lee, 2018, Human molecular genetics.

Frontotemporal Dementia Patient Neurons With Progranulin Deficiency Display Protein Dyshomeostasis

S. Gygi, S. Finkbeiner, J. Paulo, 2023, bioRxiv.

Loss of the deubiquitinase USP36 destabilizes the RNA helicase DHX33 and causes preimplantation lethality in mice

S. Gygi, J. Martín-Subero, C. López-Otín, 2017, The Journal of Biological Chemistry.

Highly Multiplexed Quantitative Mass Spectrometry Analysis of Ubiquitylomes.

S. Gygi, J. Harper, Mark P. Jedrychowski, 2016, Cell systems.

TRAF-mediated modulation of NF-kB AND JNK activation by TNFR2.

Miguel A. Prado, Lucía Cabal-Hierro, P. S. Lazo, 2014, Cellular signalling.

Proteostasis and lysosomal quality control deficits in Alzheimer’s disease neurons

S. Gygi, J. Frydman, T. Wyss-Coray, 2023, bioRxiv.

Chromatin accessibility promotes hematopoietic and leukemia stem cell activity

Henry W. Long, S. Gygi, B. Bernstein, 2020, Nature Communications.

Correction for Wu et al., ALS/FTD mutations in UBQLN2 impede autophagy by reducing autophagosome acidification through loss of function

C. Shaw, T. Siddique, Alexandra, 2021, Proceedings of the National Academy of Sciences of the United States of America.

Targeting pleckstrin-2/Akt signaling reduces proliferation in myeloproliferative neoplasm models

J. Paulo, L. Stephens, P. Weber, 2023, Journal of Clinical Investigation.

PROTEOSTASIS UBE 2 O remodels the proteome during terminal erythroid differentiation

M. Justice, S. Gygi, M. Fleming, 2017 .

Phosphorylation of human eukaryotic elongation factor 1Bγ is regulated by paclitaxel

C. Martínez-Campa, Miguel A. Prado, P. Casado, 2007, Proteomics.