I. Peng

发表

Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins

S. Gygi, J. Paulo, Z. Modrušan, 2017, eLife.

Lead optimization of a 4-aminopyridine benzamide scaffold to identify potent, selective, and orally bioavailable TYK2 inhibitors.

Adam R. Johnson, Jun Liang, J. DeVoss, 2013, Journal of medicinal chemistry.

Actin-Bundling Protein L-Plastin Regulates T Cell Activation

D. Danilenko, J. DeVoss, P. Allen, 2010, The Journal of Immunology.

RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury

N. van Bruggen, M. Hedehus, J. DeVoss, 2016, Cell Death and Differentiation.

IL-17RC Is Required for IL-17A– and IL-17F–Dependent Signaling and the Pathogenesis of Experimental Autoimmune Encephalomyelitis

D. Danilenko, W. Ouyang, P. Caplazi, 2010, The Journal of Immunology.

Lung-restricted inhibition of Janus kinase 1 is effective in rodent models of asthma

Adam R. Johnson, N. C. Ray, G. Cain, 2018, Science Translational Medicine.

CXCL14 is a candidate biomarker for Hedgehog signalling in idiopathic pulmonary fibrosis

M. Yaylaoglu, H. Collard, J. Egen, 2017, Thorax.

Targeted depletion of lymphotoxin-α–expressing TH1 and TH17 cells inhibits autoimmune disease

M. Balázs, L. Diehl, E. Chiang, 2009, Nature Medicine.

An anti-B7-H4 antibody-drug conjugate for the treatment of breast cancer.

J. DeVoss, T. Pham, Cécile Chalouni, 2015, Molecular pharmaceutics.

Potassium channels Kv1.3 and KCa3.1 cooperatively and compensatorily regulate antigen-specific memory T cell functions

J. DeVoss, S. Warming, Tianbo Li, 2017, Nature Communications.

Dendritic cells require NIK for CD40-dependent cross-priming of CD8+ T cells

I. Mellman, Lawren C. Wu, L. Delamarre, 2015, Proceedings of the National Academy of Sciences.

Critical role of activation induced cytidine deaminase in Experimental Autoimmune Encephalomyelitis

J. DeVoss, A. Zarrin, S. Warming, 2012, Autoimmunity.

Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model.

Adam R. Johnson, Jun Liang, J. DeVoss, 2017, Bioorganic & medicinal chemistry letters.

A Crohn’s disease variant in Atg16l1 enhances its degradation by caspase 3

J. DeVoss, R. Graham, L. Diehl, 2014, Nature.

Selective autophagy of the adaptor TRIF regulates innate inflammatory signaling

M. van Lookeren Campagne, J. Hackney, E. Verschueren, 2018, Nature Immunology.

Inhibition of the kinase ITK in a mouse model of asthma reduces cell death and fails to inhibit the inflammatory response

J. DeVoss, A. Zarrin, Lawren C. Wu, 2015, Science Signaling.

The kinase TPL2 activates ERK and p38 signaling to promote neutrophilic inflammation

Z. Modrušan, J. DeVoss, A. Zarrin, 2017, Science Signaling.

Genetic inactivation of RIP1 kinase activity in rats protects against ischemic brain injury

K. Stark, J. Webster, E. Verschueren, 2021, Cell Death and Disease.

PILRα Negatively Regulates Mouse Inflammatory Arthritis

S. Kummerfeld, W. Ouyang, J. DeVoss, 2014, The Journal of Immunology.

Tumor suppressor BAP1 is essential for thymic development and proliferative responses of T lymphocytes

Thijs J. Hagenbeek, Steve Lianoglou, S. Rutz, 2018, Science Immunology.

NRROS negatively regulates reactive oxygen species during host defence and autoimmunity

S. Rutz, P. Valdez, Z. Modrušan, 2014, Nature.