J. Downie

发表

Genome sequence and genetic diversity of European ash trees

Bernardo J. Clavijo, D. Swarbreck, M. Cáccamo, 2016, Nature.

Genes involved in the formation and assembly of rhizobial cytochromes and their role in symbiotic nitrogen fixation.

M. Delgado, E. Bedmar, J. Downie, 1998, Advances in microbial physiology.

Amino-acid cycling drives nitrogen fixation in the legume–Rhizobium symbiosis

D. Allaway, P. Poole, K. Findlay, 2003, Nature.

Coordinating nodule morphogenesis with rhizobial infection in legumes.

J. Downie, G. Oldroyd, 2008, Annual review of plant biology.

Nodulation Signaling in Legumes Requires NSP2, a Member of the GRAS Family of Transcriptional Regulators

J. F. Marsh, J. Rogers, S. Sims, 2005, Science.

Legume nodulation

J. Downie, 2014, Current Biology.

The nodD gene of Rhizobium leguminosarum is autoregulatory and in the presence of plant exudate induces the nodA,B,C genes

C. Shearman, J. Downie, L. Rossen, 1985, The EMBO journal.

The Rhizobium leguminosarum nodulation gene nodF encodes a polypeptide similar to acyl‐carrier protein and is regulated by nodD plus a factor in pea root exudate

C. Shearman, J. Downie, L. Rossen, 1986, The EMBO journal.

Characterization of the Rhizobium leguminosarum genes nodLMN involved in efficient host‐specific nodulation

J. Downie, B. Surin, 1988, Molecular microbiology.

Functions of Rhizobial Nodulation Genes

J. Downie, 1998 .

Signalling strategies for nodulation of legumes by rhizobia.

J. Downie, 1994, Trends in microbiology.

The psi operon of Rhizobium leguminosarum biovar phaseoli: identification of two genes whose products are located at the bacterial cell surface.

M. Mimmack, D. Borthakur, J. Downie, 1994, Microbiology.

The sym plasmid pRP2JI and at least two other loci of Rhizobium leguminosarum biovar phaseoli can confer resistance to infection by the virulent bacteriophage RL38

J. Downie, A. Johnston, G. Jun, 1993 .

Molecular characterization and regulation of the rhizosphere-expressed genes rhiABCR that can influence nodulation by Rhizobium leguminosarum biovar viciae

J. Downie, G. Murphy, A. Economou, 1992, Journal of bacteriology.

Cloning of the symbiotic region of Rhizobium leguminosarum: the nodulation genes are between the nitrogenase genes and a nifA‐like gene

J. Downie, C. Knight, A. Johnston, 1983, The EMBO journal.

Cloning of the nodulation (nod) genes of Rhizobium phaseoli and their homology to R. leguminosarum nod DNA.

J. Downie, J. Lamb, A. Johnston, 1985, Gene.

psi, a plasmid-linked Rhizobium phaseoli gene that inhibits exopolysaccharide production and which is required for symbiotic nitrogen fixation

D. Borthakur, J. Downie, J. Lamb, 1985, Molecular and General Genetics MGG.

Cloned nodulation genes of Rhizobium leguminosarum determine host-range specificity

J. Downie, C. Knight, A. Johnston, 1983, Molecular and General Genetics MGG.

Molecular characterization of the nodulation gene, nodT, from two biovars of Rhizobium leguminosarum

J. Watson, J. Downie, W. Hamilton, 1990, Molecular microbiology.

Identification and DNA sequence of fixZ, a nifB-like gene from Rhizobium leguminosarum.

J. Downie, L. Rossen, A. Johnston, 1984, Nucleic acids research.

Nonlinear Time Series Analysis of Nodulation Factor Induced Calcium Oscillations: Evidence for Deterministic Chaos?

Derin B. Wysham, R. Morris, J. Downie, 2009, PloS one.

Quorum sensing as a population-density-dependent determinant of bacterial physiology.

N. A. Whitehead, G. Salmond, S. Swift, 2001, Advances in microbial physiology.

Atypical Receptor Kinase RINRK1 Required for Rhizobial Infection But Not Nodule Development in Lotus japonicus1[OPEN]

J. Stougaard, S. U. Andersen, J. Downie, 2019, Plant Physiology.

The roles of extracellular proteins, polysaccharides and signals in the interactions of rhizobia with legume roots.

J. Downie, 2010, FEMS microbiology reviews.

Bacterial conversations : talking , listening and eavesdropping

I. Joint, J. Downie, 2008 .

Identification of symbiosis-specific c-type cytochromes and a putative oxidase in bacteroids of Rhizobium leguminosarum biovar viciae.

C. Vargas, M. Delgado, R. Poole, 1996, Microbiology.

The Structure and Regulation of the Nodulation Genes of Rhizobium Leguminosarum

I. J. Evans, C. Shearman, J. Downie, 1985 .

The Rhizobium leguminosarum prsDE genes are required for secretion of several proteins, some of which influence nodulation, symbiotic nitrogen fixation and exopolysaccharide modification

C. Finnie, K. Findlay, J. Downie, 1997, Molecular microbiology.

The nodulation-signaling protein NodO from Rhizobium leguminosarum biovar viciae forms ion channels in membranes.

J. Downie, J. M. Sutton, E. Lea, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Heterologous expression of the immune receptor EFR in Medicago truncatula reduces pathogenic infection, but not rhizobial symbiosis

C. Zipfel, J. Downie, N. Peeters, 2017, bioRxiv.

Analysis of N-acyl homoserine-lactone quorum-sensing molecules made by different strains and biovars of Rhizobium leguminosarum containing different symbiotic plasmids

J. Downie, J. Jones, V. Danino, 2004, Plant and Soil.

Analysis of N-acyl homoserine-lactone quorum-sensing molecules made by different strains and biovars of Rhizobium leguminosarum containing different symbiotic plasmids

J. Downie, J. Jones, V. Danino, 2002 .

MgtE From Rhizobium leguminosarum Is a Mg²⁺ Channel Essential for Growth at Low pH and N2 Fixation on Specific Plants.

P. Poole, J. Downie, R. Karunakaran, 2015, Molecular plant-microbe interactions : MPMI.

The ERN1 transcription factor gene is a target of the CCaMK/CYCLOPS complex and controls rhizobial infection in Lotus japonicus.

Trevor L. Wang, M. Parniske, Quanhui Wang, 2017, The New phytologist.

A Pectate Lyase Required for Plant Cell‐Wall Remodeling During Infection of Legumes by Rhizobia

J. Downie, Fang Xie, 2015 .

Legume pectate lyase required for root infection by rhizobia

A. Edwards, J. Murray, J. Downie, 2011, Proceedings of the National Academy of Sciences.

A sound approach to GM debate

D. Goldhaber-Gordon, J. Young, J. Downie, 2001, Nature.

Rhizobium leguminosarum has two glucosamine syntheses, GImS and NodM, required for nodulation and development of nitrogen‐fixing nodules

J. Downie, C. Marie, M. Barny, 1992, Molecular microbiology.

A nucleoporin is required for induction of Ca2+ spiking in legume nodule development and essential for rhizobial and fungal symbiosis.

S. Tabata, T. Jensen, Yasukazu Nakamura, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Analysis of Nod-factor-induced calcium signaling in root hairs of symbiotically defective mutants of Lotus japonicus.

J. Downie, G. Oldroyd, Jongho Sun, 2006, Molecular plant-microbe interactions : MPMI.

Rhizobial and Mycorrhizal Symbioses in Lotus japonicus Require Lectin Nucleotide Phosphohydrolase, Which Acts Upstream of Calcium Signaling1[C][W][OA]

M. Etzler, A. Rose, A. Edwards, 2012, Plant Physiology.

Positional cloning identifies Lotus japonicus NSP2, a putative transcription factor of the GRAS family, required for NIN and ENOD40 gene expression in nodule initiation.

H. Kouchi, S. Kawasaki, M. Kawaguchi, 2006, DNA research : an international journal for rapid publication of reports on genes and genomes.

The superoxide dismutase SodA is targeted to the periplasm in a SecA‐dependent manner by a novel mechanism

A. Edwards, M. Krehenbrink, J. Downie, 2011, Molecular microbiology.

Conservation in function of a SCAR/WAVE component during infection thread and root hair growth in Medicago truncatula.

Colby G Starker, J. Downie, G. Oldroyd, 2010, Molecular plant-microbe interactions : MPMI.

Mapping of the nodulation loci sym9 and sym10 of pea (Pisum sativum L.)

G. Duc, T. Ellis, M. Sagan, 2002, Theoretical and Applied Genetics.

The ash dieback invasion of Europe was founded by two genetically divergent individuals

Neil Hall, Bernardo J. Clavijo, Mark Blaxter, 2018, Nature Ecology & Evolution.

Ash dieback epidemic in Europe: How can molecular technologies help?

J. Downie, 2017, PLoS pathogens.

Dissection of nodulation signaling using pea mutants defective for calcium spiking induced by nod factors and chitin oligomers.

J. Downie, V. Viprey, S. Walker, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Why Should Nodule Cysteine-Rich (NCR) Peptides Be Absent From Nodules of Some Groups of Legumes but Essential for Symbiotic N-Fixation in Others?

E. Kondorosi, J. Downie, 2021, Frontiers in Agronomy.

Bacterial‐induced calcium oscillations are common to nitrogen‐fixing associations of nodulating legumes and non‐legumes

P. Normand, R. Morris, R. Geurts, 2015, The New phytologist.

Arabinose and protocatechuate catabolism genes are important for growth of Rhizobium leguminosarum biovar viciae in the pea rhizosphere

A. Edwards, P. Poole, P. García-Fraile, 2015, Plant and Soil.

SCARN a Novel Class of SCAR Protein That Is Required for Root-Hair Infection during Legume Nodulation

Trevor L. Wang, M. Parniske, Shusei Sato, 2015, PLoS genetics.

Rearrangement of Actin Cytoskeleton Mediates Invasion of Lotus japonicus Roots by Mesorhizobium loti[C][W]

M. Hossain, S. Tabata, J. Stougaard, 2009, The Plant Cell Online.

Development and good breeding in legume models: poise and peas?: Molecular Genetics of Model Legumes.

P. Bonfante, J. Downie, 2000, The New phytologist.

Plant responses to nodulation factors.

J. Downie, S. Walker, 1999, Current opinion in plant biology.

Annexins - calcium- and membrane-binding proteins in the plant kingdom: potential role in nodulation and mycorrhization in Medicago truncatula.

J. Downie, J. Cullimore, Fernanda de Carvalho-Niebel, 2009, Acta biochimica Polonica.

Cloning and mutagenesis of nodulation genes from Rhizobium leguminosarum TOM, a strain with extended host range

J. Downie, N. J. Brewin, N. Dibb, 1984, Molecular and General Genetics MGG.

The nodI gene product of Rhizobium leguminosarum is closely related to ATP-binding bacterial transport proteins; nucleotide sequence analysis of the nodI and nodJ genes.

I. J. Evans, J. Downie, 1986, Gene.

35 – RHIZOBIUM GENETICS AND ITS APPLICATIONS

J. Downie, N. J. Brewin, A. Johnston, 1985 .

What makes the rhizobia-legume symbiosis so special?

A. Hirsch, J. Downie, M. Lum, 2001, Plant physiology.

Update on Rhizobia-Legume Symbiosis What Makes the Rhizobia-Legume Symbiosis So Special ? 1

A. Hirsch, J. Downie, M. Lum, 2001 .

Plant-Microorganism Symbiosis

J. Downie, N. J. Brewin, 1999 .

The PTSNtr system globally regulates ATP‐dependent transporters in Rhizobium leguminosarum

P. Poole, J. Downie, R. Karunakaran, 2012, Molecular microbiology.

Determinants of Nodulation Efficiency in the Symbiosis between Pisum Sativum and Rhizobium Leguminosarum

C. Finnie, J. Downie, J. Firmin, 1995 .

Rhizobium leguminosarum NodT is related to a family of outer-membrane transport proteins that includes TolC, PrtF, CyaE and AprF.

R. Rivilla, J. Downie, J. M. Sutton, 1995, Gene.

Bacterial Biosensors for in Vivo Spatiotemporal Mapping of Root Secretion1[CC-BY]

Marcela A. Mendoza-Suárez, J. Tomek, A. Edwards, 2017, Plant Physiology.

Breakthrough Technologies Bacterial Biosensors for in Vivo Spatiotemporal Mapping of Root Secretion 1 [ CC-BY ]

Marcela A. Mendoza-Suárez, J. Tomek, A. Edwards, 2017 .

Analysis of the Rhizobium leguminosarum siderophore-uptake gene fhuA: differential expression in free-living bacteria and nitrogen-fixing bacteroids and distribution of an fhuA pseudogene in different strains.

F. Wisniewski-Dyé, J. Downie, J. B. Stevens, 2000, Microbiology.

NodO: A Nodulation Protein That Forms Pores in Membranes

R. Rivilla, J. Downie, E. Lea, 1993 .

Plant biology: Locks, keys and symbioses

M. Parniske, J. Downie, J. A. Downie, 2003, Nature.

Molecular markers for tolerance of European ash (Fraxinus excelsior) to dieback disease identified using Associative Transcriptomics

Sophie H. Janacek, M. Trick, I. Bancroft, 2016, Scientific Reports.

Identification of genes and gene products involved in the nodulation of peas by Rhizobium leguminosarum

J. Downie, C. Knight, L. Rossen, 1985, Molecular and General Genetics MGG.

Secretion of the Rhizobium leguminosarum nodulation protein NodO by haemolysin‐type systems

G. Hong, J. Downie, A. Economou, 1992, Molecular microbiology.

Transcriptomic analysis of Rhizobium leguminosarum bacteroids in determinate and indeterminate nodules

P. Poole, J. Downie, R. Karunakaran, 2019, Microbial genomics.

The cytochrome bc1 complex but not CycM is necessary for symbiotic nitrogen fixation by Rhizobium leguminosarum.

C. Vargas, M. Delgado, G. Wu, 1996, Microbiology.

Characterization of the cycHJKL genes involved in cytochrome c biogenesis and symbiotic nitrogen fixation in Rhizobium leguminosarum

C. Vargas, M. Delgado, G. Wu, 1995, Journal of bacteriology.

Structural implications of mutations in the pea SYM8 symbiosis gene, the DMI1 ortholog, encoding a predicted ion channel.

A. Edwards, G. Duc, J. Downie, 2007, Molecular plant-microbe interactions : MPMI.

Entry of Rhizobium leguminosarum bv.viciae into root hairs requires minimal Nod factor specificity, but subsequent infection thread growth requires nodO or nodE.

J. Downie, S. Walker, J. A. Downie, 2000, Molecular plant-microbe interactions : MPMI.

Sym2 of Pea Is Involved in a Nodulation Factor-Perception Mechanism That Controls the Infection Process in the Epidermis

T. Bisseling, R. Geurts, A. van Kammen, 1997, Plant physiology.

Genetic mapping and functional analysis of a nodulation-defective mutant (sym19) of pea (Pisum sativum L.)

T. Ellis, M. Sagan, S. Poyser, 1999, Molecular and General Genetics MGG.

Crystallization and preliminary diffraction studies of NodL, a rhizobial O‐acetyl‐transferase involved in the host‐specific nodulation of legume roots

W. V. Shaw, P. Moody, J. Downie, 1996, Protein science : a publication of the Protein Society.

The Rhizobium leguminosarum bv. viciae NodO protein compensates for the exported signal made by the host-specific nodulation genes

J. Downie, A. Economou, C. Marie, 1990 .

Exopolysaccharide II Production Is Regulated by Salt in the Halotolerant Strain Rhizobium melilotiEFB1

J. M. Rubio, J. Lloret, R. Rivilla, 1998, Applied and Environmental Microbiology.

RPG interacts with E3-ligase CERBERUS to mediate rhizobial infection in Lotus japonicus

Trevor L. Wang, M. Parniske, J. Downie, 2022, bioRxiv.

The nodL gene from Rhizobium leguminosarum is homologous to the acetyl transferases encoded by lacA and cysE

J. Downie, 1989, Molecular microbiology.

A H+-ATPase That Energizes Nutrient Uptake during Mycorrhizal Symbioses in Rice and Medicago truncatulaC

K. Mysore, J. Murray, J. Downie, 2014 .

Nodulation of legumes by rhizobium

J. Downie, A. Johnston, 1988 .

Molecular analysis of the Rhizobium genes involved in the induction of nitrogen-fixing nodules on legumes

R. Haselkorn, C. Shearman, J. Sprent, 1987 .

The Nodulation Genes of Rhizobium Leguminosarum

I. J. Evans, C. Shearman, J. Downie, 1984 .

Extracellular Glycanases of Rhizobium leguminosarum Are Activated on the Cell Surface by an Exopolysaccharide-Related Component

C. Finnie, J. Downie, Á. Zorreguieta, 2000, Journal of bacteriology.

Identification of a Rhizobium leguminosarum gene homologous to nodT but located outside the symbiotic plasmid.

R. Rivilla, J. Downie, 1994, Gene.

Co‐ordination of quorum‐sensing regulation in Rhizobium leguminosarum by induction of an anti‐repressor

A. Edwards, J. Downie, C. McAnulla, 2011, Molecular microbiology.

Molecular cloning and genetic organization of C4-dicarboxylate transport genes from Rhizobium leguminosarum

C. Ronson, J. Downie, P. Astwood, 1984, Journal of bacteriology.

A mutation that blocks exopolysaccharide synthesis prevents nodulation of peas by Rhizobium leguminosarum but not of beans by R. phaseoli and is corrected by cloned DNA from Rhizobium or the phytopathogen Xanthomonas

D. Borthakur, J. Downie, J. Lamb, 1986, Molecular and General Genetics MGG.

Rhizobium leguminosarum nodulation gene (nod) expression is lowered by an allele-specific mutation in the dicarboxylate transport gene dctB.

P. Poole, J. Downie, A. Johnston, 1995, Microbiology.

The Rhizobium leguminosarum biovar viciae nodO gene can enable a nodE mutant of Rhizobium leguminosarum biovar trifolii to nodulate vetch

J. Downie, A. Economou, A. Johnston, 1994 .

Identification of symbiotically defective mutants of Lotus japonicus affected in infection thread growth.

J. Perry, Trevor L. Wang, M. Parniske, 2006, Molecular plant-microbe interactions : MPMI.

Quorum-Sensing Regulation in Rhizobium leguminosarum biovar viciae

J. Downie, 2015 .

Cell-to-Cell Communication in Rhizobia: Quorum Sensing and Plant Signaling

J. Downie, Juan E. González, 2008 .

Identification of a gene encoding a thioredoxin-like product necessary for cytochrome c biosynthesis and symbiotic nitrogen fixation in Rhizobium leguminosarum

C. Vargas, G. Wu, J. Downie, 1994, Journal of bacteriology.

Role of polyhydroxybutyrate and glycogen as carbon storage compounds in pea and bean bacteroids.

P. Poole, T. Wheeler, K. Findlay, 2005, Molecular plant-microbe interactions : MPMI.

Nodulation inhibition by Rhizobium leguminosarum multicopy nodABC genes and analysis of early stages of plant infection

J. Downie, C. Knight, L. Rossen, 1986, Journal of bacteriology.

raiIR Genes Are Part of a Quorum-Sensing Network Controlled by cinI and cinR in Rhizobium leguminosarum

F. Wisniewski-Dyé, J. Downie, J. Jones, 2002, Journal of bacteriology.

Calcium, kinases and nodulation signalling in legumes

J. Downie, G. Oldroyd, 2004, Nature Reviews Molecular Cell Biology.

A Ca2+/calmodulin-dependent protein kinase required for symbiotic nodule development: Gene identification by transcript-based cloning.

A. Edwards, J. Downie, G. Oldroyd, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Proteins Exported via the PrsD-PrsE Type I Secretion System and the Acidic Exopolysaccharide Are Involved in Biofilm Formation by Rhizobium leguminosarum

A. Edwards, C. Finnie, J. Downie, 2006, Journal of bacteriology.

Buffering Capacity Explains Signal Variation in Symbiotic Calcium Oscillations1[C][W][OA]

Derin B. Wysham, K. Tsaneva-Atanasova, R. Morris, 2012, Plant Physiology.

Physiology Of Root-Nodule Bacteria

P. Poole, M. Hynes, J. Downie, 2008 .

Differential and chaotic calcium signatures in the symbiosis signaling pathway of legumes

Richard J Morris, Saul Hazledine, R. Morris, 2008, Proceedings of the National Academy of Sciences.

Lipopolysaccharide O-Chain Core Region Required for Cellular Cohesion and Compaction of In Vitro and Root Biofilms Developed by Rhizobium leguminosarum

J. Downie, Á. Zorreguieta, P. Abdian, 2014, Applied and Environmental Microbiology.

The O-chain core region of the lipopolysaccharide is required for cellular cohesion 1 and compaction of in vitro and root biofilms developed by Rhizobium 2 leguminosarum 3 4

J. Downie, P. Abdian, E. Kannenberg, 2014 .

Glucomannan-Mediated Attachment of Rhizobium leguminosarum to Pea Root Hairs Is Required for Competitive Nodule Infection

M. Krehenbrink, J. Downie, Á. Zorreguieta, 2008, Journal of bacteriology.

A plant arabinogalactan-like glycoprotein promotes a novel type of polar surface attachment by Rhizobium leguminosarum.

A. Edwards, J. Downie, Fang Xie, 2012, Molecular plant-microbe interactions : MPMI.

Mutation of praR in Rhizobium leguminosarum enhances root biofilms, improving nodulation competitiveness by increased expression of attachment proteins

A. Edwards, P. Poole, M. Sánchez-Contreras, 2014, Molecular microbiology.

Identification of protein secretion systems and novel secreted proteins in Rhizobium leguminosarum bv. viciae

M. Krehenbrink, J. Downie, 2008, BMC Genomics.

Characterization of Rhizobium leguminosarum Exopolysaccharide Glycanases That Are Secreted via a Type I Exporter and Have a Novel Heptapeptide Repeat Motif

C. Finnie, J. Downie, N. Hartley, 1998, Journal of bacteriology.

Research NotesIdentification of the NodC Protein in the Inner but Not the Outer Membrane ofRhizobium leguminosarum

J. Downie, M. Barny, 1993 .

DNA sequence of the Rhizobium leguminosarum nodulation genes nodAB and C required for root hair curling.

J. Downie, L. Rossen, A. Johnston, 1984, Nucleic acids research.

A Common Genomic Framework for a Diverse Assembly of Plasmids in the Symbiotic Nitrogen Fixing Bacteria

Georgios S. Vernikos, Lisa C. Crossman, J. Parkhill, 2008, PloS one.

The rules of engagement in the legume-rhizobial symbiosis.

P. Poole, J. Murray, J. Downie, 2011, Annual review of genetics.

A eulogy to Adam Kondorosi.

J. Downie, 2011, Molecular plant-microbe interactions : MPMI.

Morphotype of bacteroids in different legumes correlates with the number and type of symbiotic NCR peptides

R. Herczeg, B. Bálint, E. Kondorosi, 2017, Proceedings of the National Academy of Sciences.

The Root Hair “Infectome” of Medicago truncatula Uncovers Changes in Cell Cycle Genes and Reveals a Requirement for Auxin Signaling in Rhizobial Infection[W][OPEN]

M. Trick, K. Mysore, A. Breakspear, 2014, Plant Cell.

Infectious Heresy

J. Downie, 2007, Science.

Resistance to nodulation of cv. Afghanistan peas is overcome by nodX, which mediates an O‐acetylation of the Rhizobium leguminosarum lipo‐oligosaccharide nodulation factor

J. Downie, R. Carlson, J. Firmin, 1993, Molecular microbiology.

Conservation of nolR in the Sinorhizobium and Rhizobium Genera of the Rhizobiaceae Family

E. Kondorosi, A. Kondorosi, J. Downie, 1998 .

GRAS Proteins Form a DNA Binding Complex to Induce Gene Expression during Nodulation Signaling in Medicago truncatula[W]

A. Muñoz, J. Downie, G. Oldroyd, 2009, The Plant Cell Online.

Widely conserved AHL transcription factors are essential for NCR gene expression and nodule development in Medicago

E. Kondorosi, A. Pettkó-Szandtner, J. Downie, 2023, Nature Plants.

Lotus japonicus Nodulation Requires Two GRAS Domain Regulators, One of Which Is Functionally Conserved in a Non-Legume1[C][W]

J. Perry, Trevor L. Wang, M. Parniske, 2006, Plant Physiology.

The Nodulation of Legumes by Rhizobia

J. Downie, A. Economou, 1992 .

Analysis of calcium spiking using a cameleon calcium sensor reveals that nodulation gene expression is regulated by calcium spike number and the developmental status of the cell.

J. Downie, G. Oldroyd, Jongho Sun, 2006, The Plant journal : for cell and molecular biology.

Natural variation in host-specific nodulation of pea is associated with a haplotype of the SYM37 LysM-type receptor-like kinase.

A. Edwards, M. Knox, T. Ellis, 2011, Molecular plant-microbe interactions : MPMI.

Competitive nodulation blocking of cv. Afghanistan pea is related to high levels of nodulation factors made by some strains of Rhizobium leguminosarum bv. viciae.

T. Bisseling, J. Downie, Bridget V. Hogg, 2002, Molecular plant-microbe interactions : MPMI.

The C‐terminal domain of the Rhizobium leguminosarum chitin synthase NodC is important for function and determines the orientation of the N‐terminal region in the inner membrane

J. Downie, A. Economou, A. Johnston, 1996, Molecular microbiology.

Calcium signals in plant immunity: a spiky issue.

J. Downie, 2014, The New phytologist.

The Medicago truncatula DMI1 Protein Modulates Cytosolic Calcium Signaling1[W][OA]

A. Edwards, Jean-Michel Ané, E. Peiter, 2007, Plant Physiology.

The Medicago truncatula DMI 1 Protein Modulates Cytosolic Calcium Signaling 1

A. Edwards, Jean-Michel Ané, E. Peiter, 2007 .

The Rhizobium nodulation gene nodO encodes a Ca2(+)‐binding protein that is exported without N‐terminal cleavage and is homologous to haemolysin and related proteins.

J. Downie, W. Hamilton, A. Economou, 1990, The EMBO journal.

Nuclear calcium changes at the core of symbiosis signalling.

J. Downie, G. Oldroyd, 2006, Current opinion in plant biology.

Plastid proteins crucial for symbiotic fungal and bacterial entry into plant roots

Naoya Takeda, Satoshi Tabata, Hiroshi Kouchi, 2005, Nature.

Crowdsourced analysis of ash and ash dieback through the Open Ash Dieback project: A year 1 report on datasets and analyses contributed by a self-organising community

Bernardo J. Clavijo, Graham J. Etherington, Lisa C. Crossman, 2014, bioRxiv.

The biocontrol strain Pseudomonas fluorescens F113 produces the Rhizobium small bacteriocin, N-(3-hydroxy-7-cis-tetradecenoyl)homoserine lactone, via HdtS, a putative novel N-acylhomoserine lactone synthase.

F. O'Gara, J. Downie, P. Williams, 2000, Microbiology.

Identification of the host-range DNA which allows Rhizobium leguminosarum strain TOM to nodulate cv. Afghanistan peas

I. J. Evans, J. Downie, A. Johnston, 1985, Molecular and General Genetics MGG.

Molecular genetics of mutants of Rhizobium leguminosarum which fail to fix nitrogen

J. Downie, A. Johnston, Q. Ma, 1982, Molecular and General Genetics MGG.

Genetic Analysis of pRL1 JI, a Symbiotic Plasmid of Rhizobium leguminosarum

J. Downie, C. Knight, A. Johnston, 1983 .

Analysis of Quorum-Sensing-Dependent Control of Rhizosphere-Expressed (rhi) Genes in Rhizobium leguminosarum bv. viciae

F. Wisniewski-Dyé, J. Downie, A. Economou, 1999, Journal of bacteriology.

Cell-to-cell signaling in the symbiotic nitrogen-fixing bacterium Rhizobium leguminosarum: autoinduction of a stationary phase and rhizosphere-expressed genes

E. Greenberg, J. Downie, J. Pearson, 1996, Journal of bacteriology.

Genome sequencing: The ABC of symbiosis

J. Young, J. Downie, 2001, Nature.

LIN, a Novel Type of U-Box/WD40 Protein, Controls Early Infection by Rhizobia in Legumes1[C][W][OA]

J. Downie, G. Oldroyd, E. Kiss, 2009, Plant Physiology.

Nuclear membranes control symbiotic calcium signaling of legumes

Derin B. Wysham, Jean-Michel Ané, R. Morris, 2011, Proceedings of the National Academy of Sciences.

Mastoparan Activates Calcium Spiking Analogous to Nod Factor-Induced Responses in Medicago truncatula Root Hair Cells1[W][OA]

J. Downie, G. Oldroyd, Jongho Sun, 2007, Plant Physiology.

NUCLEOPORIN85 Is Required for Calcium Spiking, Fungal and Bacterial Symbioses, and Seed Production in Lotus japonicus

S. Tabata, M. Parniske, E. Asamizu, 2007, The Plant Cell Online.

N-Acyl-Homoserine Lactone Inhibition of Rhizobial Growth Is Mediated by Two Quorum-Sensing Genes That Regulate Plasmid Transfer

F. Wisniewski-Dyé, J. Downie, A. Wilkinson, 2002, Journal of bacteriology.

The regulatory locus cinRI in Rhizobium leguminosarum controls a network of quorum‐sensing loci

F. Wisniewski-Dyé, J. Downie, B. Rodelas, 2000, Molecular microbiology.

Plant cysteine-rich peptides that inhibit pathogen growth and control rhizobial differentiation in legume nodules.

G. Maróti, E. Kondorosi, J. Downie, 2015, Current opinion in plant biology.

News & Notes: Primary Structure of the DNA Polymerase I Gene of an α-Proteobacterium, Rhizobium leguminosarum, and Comparison with Other Family A DNA Polymerases

J. Ito, J. Downie, Yi-Ping Huang, 1999, Current Microbiology.

Biochemical and molecular studies of symbiotic nitrogen fixation.

F. J. Bruijn, J. Downie, 1991, Current opinion in biotechnology.

Manganese transport is essential for N2‐fixation by Rhizobium leguminosarum in bacteroids from galegoid but not phaseoloid nodules

P. Poole, J. Downie, V. Ramachandran, 2017, Environmental microbiology.

Two of the three groEL homologues in Rhizobium leguminosarum are dispensable for normal growth

Phillip S. Gould, P. Lund, J. Downie, 2005, Archives of Microbiology.

Effects of calcium and protons on the secondary structure of the nodulation protein NodO from Rhizobium leguminosarum biovar viciae.

J. Downie, M. Serra, G. Menestrina, 1999, Biochemical and biophysical research communications.

Adaptation of Rhizobium leguminosarum to pea, alfalfa and sugar beet rhizospheres investigated by comparative transcriptomics

P. Poole, J. Downie, R. Karunakaran, 2011, Genome Biology.

Either of two nod gene loci can complement the nodulation defect of a nod deletion mutant of Rhizobium leguminosarum bv viciae

J. Downie, B. Surin, 1990, Molecular and General Genetics MGG.

Protein domains and architectural innovation in plant-associated Proteobacteria

David J Studholme, Gail M Preston, D. Studholme, 2005, BMC Genomics.

A H+-ATPase That Energizes Nutrient Uptake during Mycorrhizal Symbioses in Rice and Medicago truncatula[C][W][OPEN]

K. Mysore, J. Murray, J. Downie, 2014, Plant Cell.

Legume Haemoglobins: Symbiotic Nitrogen Fixation Needs Bloody Nodules

J. Downie, Allan Downie, 2005, Current Biology.

Enhanced Symbiotic Performance by Rhizobium tropici Glycogen Synthase Mutants

Francisco Temprano, M. Megias, M. Soberón, 2001, Journal of bacteriology.

High affinity iron acquisition in Rhizobium leguminosarum requires the cycHJKL operon and the feuPQ gene products, which belong to the family of two-component transcriptional regulators.

M. Delgado, J. Downie, M. Wexler, 1997, Microbiology.

Rhizobium Leguminosarum Genes Involved in Early Stages of Nodulation

J. Downie, C. Knight, L. Rossen, 1985, Journal of Cell Science.

Identification of a rhizosphere protein encoded by the symbiotic plasmid of Rhizobium leguminosarum

J. Downie, N. J. Brewin, N. Dibb, 1984, Journal of bacteriology.

MtLAX2, a Functional Homologue of the Arabidopsis Auxin Influx Transporter AUX1, Is Required for Nodule Organogenesis1[CC-BY]

M. Bennett, Xiaofei Cheng, R. Swarup, 2017, Plant Physiology.

MtLAX 2 , a Functional Homologue of the Arabidopsis Auxin In fl ux Transporter AUX 1 , Is Required for Nodule Organogenesis 1 [ CC-BY ]

M. Bennett, Xiaofei Cheng, R. Swarup, 2017 .

Host-specific Nod-factors associated with Medicago truncatula nodule infection differentially induce calcium influx and calcium spiking in root hairs

R. Morris, H. Driguez, J. Downie, 2013, The New phytologist.

The Legume–Rhizobium Symbiosis: A Cell Surface Interaction

J. Downie, N. J. Brewin, C. Knight, 1985, Journal of Cell Science.

Plant biology: Fixation with regulation

M. Parniske, J. Downie, 2002, Nature.

Quorum-sensing in Rhizobium

F. Wisniewski-Dyé, J. Downie, J. Downie, 2002, Antonie van Leeuwenhoek.

Recipient‐induced transfer of the symbiotic plasmid pRL1JI in Rhizobium leguminosarum bv. viciae is regulated by a quorum‐sensing relay

A. Edwards, J. Downie, A. Wilkinson, 2003, Molecular microbiology.

Analysis of the C-terminal secretion signal of the Rhizobium leguminosarum nodulation protein NodO; a potential system for the secretion of heterologous proteins during nodule invasion.

J. Downie, J. Peart, G. Dean, 1996, Molecular plant-microbe interactions : MPMI.

Cloning of a multicopy plasmid from the actinorhizad nitrogen-fixing bacterium Frankia sp. and determination of its restriction map.

P. Normand, J. Downie, T. Kieser, 1985, Gene.

The cin and rai Quorum-Sensing Regulatory Systems in Rhizobium leguminosarum Are Coordinated by ExpR and CinS, a Small Regulatory Protein Coexpressed with CinI

A. Edwards, F. Wisniewski-Dyé, J. Downie, 2009, Journal of bacteriology.

Expression of the Arabidopsis thaliana immune receptor EFR in Medicago truncatula reduces infection by a root pathogenic bacterium, but not nitrogen‐fixing rhizobial symbiosis

C. Zipfel, J. Downie, N. Peeters, 2018, Plant biotechnology journal.

Isolation of a DNA polymerase I (polA) mutant of Rhizobium leguminosarum that has significantly reduced levels of an IncQ-group plasmid

J. Downie, S. Crank, 2004, Molecular and General Genetics MGG.

Quorum-sensing-regulated transcriptional initiation of plasmid transfer and replication genes in Rhizobium leguminosarum biovar viciae.

Craig McAnulla, A. Edwards, R. Sawers, 2007, Microbiology.

Author response: Lessons from Fraxinus, a crowd-sourced citizen science game in genomics

Bernardo J. Clavijo, D. Swarbreck, D. MacLean, 2015 .