D. R. Compton

发表

The pharmacological activity of anandamide, a putative endogenous cannabinoid, in mice.

P. Smith, R. Mechoulam, D. R. Compton, 1994, The Journal of pharmacology and experimental therapeutics.

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors.

Z. Vogel, S. Almog, N. Kaminski, 1995, Biochemical pharmacology.

Evaluation of cannabinoid receptor binding and in vivo activities for anandamide analogs.

B. Thomas, D. R. Compton, R. Razdan, 1995, The Journal of pharmacology and experimental therapeutics.

Modeling the cannabinoid receptor: a three-dimensional quantitative structure-activity analysis.

S. Semus, B. Thomas, D. R. Compton, 1991, Molecular pharmacology.

Ontogeny of mu opioid agonist anti-nociception in postnatal rats.

S. R. Thornton, F. L. Smith, D. R. Compton, 1998, Brain research. Developmental brain research.

Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors.

D. R. Compton, B. Martin, G. Kunos, 1997, The Journal of pharmacology and experimental therapeutics.

Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands.

D. R. Compton, B. Martin, V. Showalter, 1996, The Journal of pharmacology and experimental therapeutics.

Cannabinoid structure-activity relationships: correlation of receptor binding and in vivo activities.

K. Rice, M. Johnson, L. Melvin, 1993, The Journal of pharmacology and experimental therapeutics.

Proarrhythmic mechanisms of the common anti-diarrheal medication loperamide: revelations from the opioid abuse epidemic

Roy J. Vaz, D. R. Compton, Jiesheng Kang, 2016, Naunyn-Schmiedeberg's Archives of Pharmacology.

In vivo characterization of a specific cannabinoid receptor antagonist (SR141716A): inhibition of delta 9-tetrahydrocannabinol-induced responses and apparent agonist activity.

J. Lowe, M. Aceto, D. R. Compton, 1996, The Journal of pharmacology and experimental therapeutics.

Stereochemical effects of 11-OH-Δ 8-THC-dimethylheptyl in mice and dogs

P. Little, R. Mechoulam, D. R. Compton, 1989, Pharmacology Biochemistry and Behavior.

Structure-activity relationships of indole- and pyrrole-derived cannabinoids.

D. R. Compton, B. Martin, J. Wiley, 1998, The Journal of pharmacology and experimental therapeutics.

Characterization of the lipophilicity of natural and synthetic analogs of delta 9-tetrahydrocannabinol and its relationship to pharmacological potency.

B. Thomas, D. R. Compton, B. Martin, 1990, The Journal of pharmacology and experimental therapeutics.

Behavioral, biochemical, and molecular modeling evaluations of cannabinoid analogs

R. Mechoulam, B. Thomas, L. Melvin, 1991, Pharmacology Biochemistry and Behavior.

Investigation of the role of the phenolic hydroxyl in cannabinoid activity.

D. R. Compton, B. Martin, P. Reggio, 1990, Molecular pharmacology.

Evaluation of Agonist-antagonist Properties of Nitrogen Mustard and Cyano Derivatives of Δ8-Tetrahydrocannabinol

A. Lichtman, Aloke K. Dutta, C. Siegel, 1996, Neuropharmacology.

5'-Azido-delta 8-THC: a novel photoaffinity label for the cannabinoid receptor.

A. Makriyannis, A. Howlett, D. R. Compton, 1992, Journal of medicinal chemistry.

Pharmacology and stereoselectivity of structurally novel cannabinoids in mice.

P. Little, M. Johnson, L. Melvin, 1988, The Journal of pharmacology and experimental therapeutics.

Pharmacological evaluation of dimethylheptyl analogs of delta 9-THC: reassessment of the putative three-point cannabinoid-receptor interaction.

R. L. Barrett, D. R. Compton, R. Razdan, 1995, Drug and alcohol dependence.

Structure-Activity Relationships of Indole-and Pyrrole-Derived Cannabinoids 1

D. R. Compton, B. Martin, J. Wiley, 1998 .

Synthesis, pharmacology, and molecular modeling of novel 4-alkyloxy indole derivatives related to cannabimimetic aminoalkyl indoles (AAIs).

Aloke K. Dutta, B. Thomas, D. R. Compton, 1997, Bioorganic & medicinal chemistry.

1-Alkyl-3-(1-naphthoyl)pyrroles: A New Class of Cannabinoid.

D. R. Compton, B. Martin, J. Huffman, 1995 .

Pharmacological evaluation of halogenated Δ 8-THC analogs

A. Makriyannis, D. R. Compton, B. Martin, 1991, Pharmacology Biochemistry and Behavior.

Abuse liability assessment for biologic drugs – All molecules are not created equal

D. R. Compton, T. Hudzik, C. Markgraf, 2018, Regulatory toxicology and pharmacology : RTP.

Agonist-antagonist characterization of 6'-cyanohex-2'-yne-delta 8-tetrahydrocannabinol in two isolated tissue preparations.

R. Pertwee, G. Griffin, D. R. Compton, 1996, European journal of pharmacology.

Aminoalkylindole analogs: cannabimimetic activity of a class of compounds structurally distinct from delta 9-tetrahydrocannabinol.

L. Gold, D. R. Compton, B. Martin, 1992, The Journal of pharmacology and experimental therapeutics.

1-ALKYL-3-(1-NAPHTHOYL)PYRROLES : A NEW CLASS OF CANNABINOID

D. R. Compton, B. Martin, J. Huffman, 1995 .

Free-radical inhibition of ATPase in hamster cheek pouch homogenates.

D. R. Compton, J. Hilton, G. Hambrecht, 1983, Life sciences.

Effects of acute and chronic clozapine and haloperidol on in vitro release of acetylcholine and dopamine from striatum and nucleus accumbens.

D. R. Compton, K. Johnson, 1989, The Journal of pharmacology and experimental therapeutics.

Pharmacological and behavioral evaluation of alkylated anandamide analogs.

D. R. Compton, R. Razdan, B. Martin, 1995, Life sciences.

Synthesis and pharmacological comparison of dimethylheptyl and pentyl analogs of anandamide.

B. Thomas, R. Pertwee, D. R. Compton, 1997, Journal of medicinal chemistry.

Development of cross-tolerance between delta 9-tetrahydrocannabinol, CP 55,940 and WIN 55,212.

L. Melvin, D. R. Compton, B. Martin, 1994, The Journal of pharmacology and experimental therapeutics.

A novel class of potent tetrahydrocannabinols (THCS): 2′-YNE-Δ8- and Δ9-THCS

D. R. Compton, R. Razdan, B. Martin, 1995 .

Side chain methyl analogues of Δ8-THC

D. R. Compton, B. Martin, J. Wiley, 1997 .

Pharmacological profile of a series of bicyclic cannabinoid analogs: classification as cannabimimetic agents.

M. Johnson, L. Melvin, D. R. Compton, 1992, The Journal of pharmacology and experimental therapeutics.

Synthesis and pharmacological properties of 11-hydroxy-3-(1',1'-dimethylheptyl)hexahydrocannabinol: a high-affinity cannabinoid agonist.

A. Makriyannis, D. R. Compton, B. Martin, 1994, Journal of medicinal chemistry.

Pharmacological evaluation of iodo and nitro analogs of Δ 8-THC and Δ 9-THC

S. Semus, Sonyuan Lin, J. Grzybowska, 1993, Pharmacology Biochemistry and Behavior.

Synthesis and pharmacological evaluation of ether and related analogues of delta 8-, delta 9-, and delta 9,11-tetrahydrocannabinol.

C. Siegel, D. R. Compton, R. Razdan, 1991, Journal of medicinal chemistry.

Synthesis and pharmacological evaluation of amino, azido, and nitrogen mustard analogues of 10-substituted cannabidiol and 11- or 12-substituted delta 8-tetrahydrocannabinol.

P. Little, D. R. Compton, R. Razdan, 1990, Journal of medicinal chemistry.

Synthesis and pharmacological evaluation of mercapto and thioacetyl analogues of cannabidiol and Δ8-tetrahydrocannabinol

P. Little, D. R. Compton, R. Razdan, 1989 .

Design, synthesis and pharmacology of cannabimimetic indoles

John W. Huffman, D. R. Compton, B. Martin, 1994 .

Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors.

T. Bonner, A. Zimmer, É. Mezey, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Cannabis dependence and tolerance production.

D. R. Compton, B. Martin, W. Dewey, 1990, Advances in alcohol & substance abuse.

Stereoselective synthesis of the epimeric Δ7-tetrahydrocannabinols

D. R. Compton, B. Martin, P. Reggio, 1995 .

Modification of phencyclidine intoxification and biodisposition by charcoal and other treatments

B. Thomas, D. R. Compton, B. Martin, 1988, Pharmacology Biochemistry and Behavior.

The effect of the enzyme inhibitor phenylmethylsulfonyl fluoride on the pharmacological effect of anandamide in the mouse model of cannabimimetic activity.

D. R. Compton, B. Martin, 1997, The Journal of pharmacology and experimental therapeutics.

Assessment of anandamide interaction with the cannabinoid brain receptor: SR 141716A antagonism studies in mice and autoradiographic analysis of receptor binding in rat brain.

D. R. Compton, B. Martin, I. B. Adams, 1998, The Journal of pharmacology and experimental therapeutics.

Cannabinoid receptors in developing rats: detection of mRNA and receptor binding.

D. R. Compton, B. Martin, M. Abood, 1994, Drug and alcohol dependence.

Neurochemistry of Abuse Liability Assessment and Primary Behavioral Correlates

D. R. Compton, T. Hudzik, 2015 .

AAV2-hAADC (Eladocagene Exuparvovec) Biodistribution and Expression: Superiority of Intraputaminal versus Intracerebroventricular and Intrathecal (Lumbar) Routes of Administration

P. Yalamanchili, S. DeMarco, D. R. Compton, 2022, International journal of toxicology.

Pharmacological characterization of BNMPA (alpha-benzyl-N-methylphenethylamine), an impurity of illicit methamphetamine synthesis.

D. R. Compton, J. Woodward, A. Poklis, 1996, European journal of pharmacology.

Pharmacological evaluation of water soluble cannabinoids and related analogs.

D. R. Compton, B. Martin, 1990, Life sciences.

Proarrhythmic mechanisms of the common anti-diarrheal medication loperamide: revelations from the opioid abuse epidemic

Roy J. Vaz, D. R. Compton, Jiesheng Kang, 2016, Naunyn-Schmiedeberg's Archives of Pharmacology.

Synthesis and pharmacology of a very potent cannabinoid lacking a phenolic hydroxyl with high affinity for the CB2 receptor.

D. R. Compton, B. Martin, J. Wiley, 1996, Journal of medicinal chemistry.

Gene therapy in the putamen for curing AADC deficiency and Parkinson's disease

K. Kiening, Takeshi Nakajima, T. Roujeau, 2021, EMBO molecular medicine.

(+)- and (-)-N-allylnormetazocine binding sites in mouse brain: in vitro and in vivo characterization and regional distribution.

D. R. Compton, B. Martin, J. Katzen, 1987, Life sciences.

Regulation of bacterial glycogen synthesis. Stimulation of glycogen synthesis by endogenous and exogenous cyclic adenosine 3':5'-monophosphate in Escherichia coli and the requirement for a functional CRP gene.

D. R. Compton, R. Ng, D. Dietzler, 1983, The Journal of biological chemistry.

A rational search for the separation of psychoactivity and analgesia in cannabinoids

G. McGaughey, D. R. Compton, B. Martin, 1991, Pharmacology Biochemistry and Behavior.

Comparative effects of interferon alpha-2b and pegylated interferon alpha-2b on menstrual cycles and ovarian hormones in cynomolgus monkeys.

B. McIntyre, D. R. Compton, B. Enright, 2009, Birth defects research. Part B, Developmental and reproductive toxicology.

Striatal synaptosomal dopamine synthesis: evidence against direct regulation by an autoreceptor mechanism.

D. R. Compton, K. Johnson, 1985, European journal of pharmacology.

A novel class of potent tetrahydrocannabinols (THCS): 2'-yne-delta 8- and delta 9-THCS.

D. R. Compton, R. Razdan, B. Martin, 1995, Life sciences.

Pharmacological evaluation of agonistic and antagonistic activity of cannabinoids.

D. R. Compton, Billy R. Martin, Little Pj, 1987, NIDA research monograph.

Stereochemical effects of 11-OH-delta 8-THC-dimethylheptyl in mice and dogs.

P. Little, R. Mechoulam, D. R. Compton, 1989, Pharmacology, biochemistry, and behavior.