G. Becker

发表

Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor.

F. Bymaster, G. Nomikos, C. Felder, 2002, The Journal of pharmacology and experimental therapeutics.

High-Throughput Biophysical Approaches to Therapeutic Protein Development

C. R. Middaugh, V. Razinkov, G. Becker, 2013 .

Osteonectin/SPARC is a product of articular chondrocytes/cartilage and is regulated by cytokines and growth factors.

M. G. Johnson, A. Harvey, S. Chandrasekhar, 1994, Biochimica et biophysica acta.

Biochemical characterization of penicillin-resistant and -sensitive penicillin-binding protein 2x transpeptidase activities of Streptococcus pneumoniae and mechanistic implications in bacterial resistance to beta-lactam antibiotics

G. Becker, R. Carnahan, W. Yeh, 1997, Journal of bacteriology.

Threonine phosphorylations induced by RX-871024 and insulin secretagogues in βTC6-F7 cells.

J. An, J. Hale, Yuguang Shi, 1999, American journal of physiology. Endocrinology and metabolism.

Characterization by Electrospray Mass Spectrometry of Human Ca2+–sensitive Cytosolic Phospholipase A2 Produced in Baculovirus–infected Insect Cells

James R. Miller, G. Becker, R. Kramer, 1994, Bio/Technology.

Mechanisms Involved in Degradation of Human Insulin by Cytosolic Fractions of Human, Monkey, and Rat Liver

V. Wroblewski, G. Becker, M. Masnyk, 1992, Diabetes.

1 BIOTECHNOLOGY-DERIVED DRUG PRODUCT DEVELOPMENT

K. Morris, G. Knipp, G. Becker, 2008 .

Purification of the O-glycosylated protein p135 and identification as O-GlcNAc transferase.

J. E. Kudlow, J. Hale, G. Becker, 2001, Biochemical and biophysical research communications.

Isolation and Characterization of a Sulfoxide and a Desamido Derivative of Biosynthetic Human Growth Hormone

G. Becker, R. Riggin, W. Bromer, 1988, Biotechnology and applied biochemistry.

Isolation and measurement of the endogenous cannabinoid receptor agonist, anandamide, in brain and peripheral tissues of human and rat

M. Palkovits, S. Paul, J. Axelrod, 1996, FEBS letters.

Biosynthesis of phosphoinositol-containing sphingolipids from phosphatidylinositol by a membrane preparation from Saccharomyces cerevisiae

G. Becker, R. Lester, 1980, Journal of bacteriology.

Liquid chromatographic control of the identity, purity and "potency" of biomolecules used as drugs.

L. M. Atkins, G. Becker, N. Farid, 1989, Journal of pharmaceutical and biomedical analysis.

Decoy receptor 3 (DcR3) is proteolytically processed to a metabolic fragment having differential activities against Fas ligand and LIGHT.

D. Witcher, V. Wroblewski, J. Richardson, 2003, Biochemical pharmacology.

Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors.

E. Diamandis, G. Sotiropoulou, G. Becker, 2003, Biochemical and biophysical research communications.

Clusterin (Apo J) protects against in vitro amyloid-beta (1-40) neurotoxicity.

P. May, G. Becker, D. Mcclure, 1996, Journal of neurochemistry.

Changes in phospholipids of Saccharomyces cerevisiae associated with inositol-less death.

G. Becker, R. Lester, 1977, The Journal of biological chemistry.

Design, synthesis, and proposed active site binding analysis of monocyclic 2-azetidinone inhibitors of prostate specific antigen.

G. Becker, B. Neubauer, R. Hermann, 2001, Journal of medicinal chemistry.

The Role of Anandamide and Related Fatty Acid Ethanolamides as Endogenous Ligands for the CB1 and CB2 Cannabinoid Receptors

M. Palkovits, J. Richardson, C. Felder, 1996 .

Prostate-specific antigen (PSA)-mediated proliferation, androgenic regulation and inhibitory effects of LY312340 in HOS-TE85 (TE85) human osteosarcoma cells.

E. Dixon, G. Becker, B. Neubauer, 2002, Anticancer research.

Purification of NADH-cytochromeb5 reductase from rat liver plasma membranes

F. L. Crane, D. Morré, G. Becker, 1995, Protoplasma.

Human cytomegalovirus maturational proteinase: expression in Escherichia coli, purification, and enzymatic characterization by using peptide substrate mimics of natural cleavage sites

H. Hsiung, D. P. Smith, W. Gibson, 1994, Journal of virology.

Design and synthesis of novel monocyclic β-lactam inhibitors of prostate specific antigen

G. Becker, B. Neubauer, R. Hermann, 1997 .

Design and Synthesis of Novel Monocyclic β-Lactam Inhibitors of Prostate Specific Antigen.

G. Becker, B. Neubauer, R. Hermann, 1997 .

Secondary structure of amyloid beta peptide correlates with neurotoxic activity in vitro.

D. Brems, R. Rydel, I. Lieberburg, 1994, Molecular pharmacology.

Use of Bacteriocin Release Protein in E. Coli for Excretion of Human Growth Hormone into the Culture Medium

H. Hsiung, B. Oudega, G. Becker, 1989, Bio/Technology.

High–Level Expression, Efficient Secretion and Folding of Human Growth Hormone in Escherichia coli

H. Hsiung, G. Becker, N. Mayne, 1986, Bio/Technology.

Proteolysis of Human Growth Hormone by Rat Thyroid Gland in Vitro: Application of Electrospray Mass Spectrometry and N-Terminal Sequencing to Elucidate a Metabolic Pathway

V. Wroblewski, G. Becker, R. Kaiser, 1993, Pharmaceutical Research.

Hormones, Human Growth Hormone

V. Wroblewski, G. Becker, R. Riggin, 2000 .

Isolation and characterization of human liver cytochrome P450 2C19: correlation between 2C19 and S-mephenytoin 4'-hydroxylation.

S. Wrighton, J. Stevens, G. Becker, 1993, Archives of biochemistry and biophysics.

Leptin is a four‐helix bundle: secondary structure by NMR

G W Becker, J. Richardson, J. Hale, 1997, FEBS letters.

Isolation and characterization of the principal ATPase associated with transitional endoplasmic reticulum of rat liver

L. Zhang, D. Morré, G. Becker, 1994, The Journal of cell biology.

Alloxan is an inhibitor of the enzyme O-linked N-acetylglucosamine transferase.

Fengxue Zhang, J. Hale, G. Becker, 2002, Biochemical and biophysical research communications.

Expression, secretion and folding of human growth hormone in Escherichia coli

H. Hsiung, G. Becker, 1986, FEBS letters.

Cloning and Expression of the Fungal Expandase/hydroxylase Gene Involved in Cephalosporin Biosynthesis

James R. Miller, G. Becker, W. Yeh, 1987, Bio/Technology.

β-amyloid peptide in vitro toxicity: Lot-to-lot variability

P. May, G. Becker, B. Gitter, 1992, Neurobiology of Aging.

Zyme, a Novel and Potentially Amyloidogenic Enzyme cDNA Isolated from Alzheimer’s Disease Brain*

James R. Miller, D. Stephenson, E. Dixon, 1997, The Journal of Biological Chemistry.

Increased sensitivity of tryptic peptide detection by MALDI-TOF mass spectrometry is achieved by conversion of lysine to homoarginine.

J. Hale, G. Becker, M. Knierman, 2000, Analytical biochemistry.

Protein mass spectrometry: applications to analytical biotechnology.

G. Becker, R. Riggin, D. Nguyen, 1995, Journal of chromatography. A.

Evidence of free and bound leptin in human circulation. Studies in lean and obese subjects and during short-term fasting.

J. Ohannesian, M. Heiman, J. Hale, 1996, The Journal of clinical investigation.

Proteolytic cleavage of human growth hormone (hGH) by rat tissues in vitro: influence on the kinetics of exogenously administered hGH.

V. Wroblewski, G. Becker, M. Masnyk, 1991, Endocrinology.

Chapter 14 Frontal Boundary Analysis In Size Exclusion Chromatography of Self-Associating Proteins

G. Becker, 1988 .

Equilibrium denaturation of human growth hormone and its cysteine-modified forms.

G W Becker, D. Brems, G. Becker, 1990, The Journal of biological chemistry.

Growth regulation of prostatic stromal cells by prostate-specific antigen.

G W Becker, H. Hsiung, P. Cohen, 1999, Journal of the National Cancer Institute.

High-throughput dynamic light scattering method for measuring viscosity of concentrated protein solutions.

Jennifer R Litowski, Linda O Narhi, Feng He, 2010, Analytical biochemistry.

Detection of IgG aggregation by a high throughput method based on extrinsic fluorescence.

Robert Bailey, Linda O Narhi, Feng He, 2010, Journal of pharmaceutical sciences.

Peptide and protein mapping by 252Cf-plasma desorption mass spectrometry.

G. Becker, A. Tsarbopoulos, I. Jardine, 1988, Analytical biochemistry.

Accelerated Formulation Development of Monoclonal Antibodies (mAbs) and mAb-Based Modalities

Vladimir I Razinkov, Michael J Treuheit, Gerald W Becker, 2015, Journal of biomolecular screening.

High-Throughput Screening and Stability Optimization of Anti-Streptavidin IgG1 and IgG2 Formulations

Vladimir I. Razinkov, M. Treuheit, V. Razinkov, 2014, Journal of biomolecular screening.

Clusterin (Apo J) Protects Against In Vitro Amyloid‐β(1–40) Neurotoxicity

P. May, G. Becker, D. Mcclure, 1996 .

Expression, purification, and characterization of active recombinant prostate‐specific antigen in Pichia pastoris (yeast)

J. Richardson, J. Hale, G. Becker, 2001, The Prostate.

Catalytic hydrogenolysis of poly-iodinated recombinant human insulin-like growth factor II (IGF-II): a potentially useful method for the tritiation of IGF-II.

J. Cook, W. J. Wheeler, G. Becker, 1991, Analytical Biochemistry.

High-throughput assessment of thermal and colloidal stability parameters for monoclonal antibody formulations.

Linda O Narhi, Feng He, Vladimir I Razinkov, 2011, Journal of pharmaceutical sciences.

Identification of a BRCA1-associated kinase with potential biological relevance

K. Cocke, S. Lemke, T. Burke, 1998, Oncogene.

Outer membrane and porin characteristics of Serratia marcescens grown in vitro and in rat intraperitoneal diffusion chambers

G. D. Campbell, G. Becker, F. Malouin, 1990, Infection and immunity.

Crystallization of Authentic Recombinant Human Growth Hormone

G. Becker, N. D. Jones, P. M. Tackitt, 1987, Bio/Technology.

Effects of sucrose and benzyl alcohol on GCSF conformational dynamics revealed by hydrogen deuterium exchange mass spectrometry.

Jun Zhang, Feng He, Michael J Treuheit, 2015, Journal of pharmaceutical sciences.

Stable isotopic labeling of proteins for quantitative proteomic applications.

G. Becker, 2008, Briefings in functional genomics & proteomics.

Screening of monoclonal antibody formulations based on high-throughput thermostability and viscosity measurements: design of experiment and statistical analysis.

Feng He, J. Litowski, L. Narhi, 2011, Journal of pharmaceutical sciences.

Screening of monoclonal antibody formulations based on high-throughput thermostability and viscosity measurements: design of experiment and statistical analysis.

J. Litowski, L. Narhi, B. Kerwin, 2011, Journal of pharmaceutical sciences.

Methods of high throughput biophysical characterization in biopharmaceutical development.

M. Treuheit, V. Razinkov, G. Becker, 2013, Current drug discovery technologies.

Two monoclonal antibodies recognizing different epitopes on rat cytochrome IIB1 react with human IIE1.

S. Wrighton, S. D. Black, P. Thomas, 1992, Molecular pharmacology.

High-Throughput Screening and Analysis of Charge Variants of Monoclonal Antibodies in Multiple Formulations

M. Treuheit, V. Razinkov, G. Becker, 2017, SLAS discovery : advancing life sciences R & D.

Purification and kinetic characterization of human cytomegalovirus assemblin.

J. Cook, G. Becker, E. Villarreal, 1994, Methods in enzymology.

Characterization of truncated kirsten-ras purified from baculovirus infected insect cells indicates heterogeneity due to N-terminal processing and nucleotide dissociation

N. Rankl, J. Richardson, J. Hale, 1997 .