G. Tiger

发表

Design, synthesis, and biological evaluation of new inhibitors of the endocannabinoid uptake: comparison with effects on fatty acid amidohydrolase.

J. Ramos, J. Fernández-Ruiz, M. López-Rodríguez, 2003, Journal of medicinal chemistry.

Fatty acid amide hydrolase: biochemistry, pharmacology, and therapeutic possibilities for an enzyme hydrolyzing anandamide, 2-arachidonoylglycerol, palmitoylethanolamide, and oleamide.

C. Fowler, G. Tiger, K. Jonsson, 2001, Biochemical pharmacology.

Serum-dependent effects of tamoxifen and cannabinoids upon C6 glioma cell viability.

C. Fowler, G. Tiger, M. Stridh, 2000, Biochemical pharmacology.

Inhibition of monoacylglycerol lipase and fatty acid amide hydrolase by analogues of 2‐arachidonoylglycerol

R. Pertwee, R. Razdan, B. Martin, 2004, British journal of pharmacology.

Inhibition of Fatty Acid Amidohydrolase, the Enzyme Responsible for the Metabolism of the Endocannabinoid Anandamide, by Analogues of Arachidonoyl-serotonin

J. Ramos, M. López-Rodríguez, A. Viso, 2003, Journal of enzyme inhibition and medicinal chemistry.

Cyclooxygenation of the arachidonoyl side chain of 1-arachidonoylglycerol and related compounds block their ability to prevent anandamide and 2-oleoylglycerol metabolism by rat brain in vitro.

C. Fowler, G. Tiger, 2005, Biochemical pharmacology.

Effects of homologues and analogues of palmitoylethanolamide upon the inactivation of the endocannabinoid anandamide

C. Fowler, G. Tiger, S. Vandevoorde, 2001, British journal of pharmacology.

The endocannabinoid signaling system: Pharmacological and therapeutic aspects

C. Fowler, G. Tiger, K. Jonsson, 2005, Pharmacology Biochemistry and Behavior.

Acidic Nonsteroidal Anti-inflammatory Drugs Inhibit Rat Brain Fatty Acid Amide Hydrolase in a pH-dependent Manner

C. Fowler, G. Tiger, S. Holt, 2003, Journal of enzyme inhibition and medicinal chemistry.

Ibuprofen inhibits rat brain deamidation of anandamide at pharmacologically relevant concentrations. Mode of inhibition and structure-activity relationship.

C. Fowler, G. Tiger, A. Stenström, 1997, The Journal of pharmacology and experimental therapeutics.

Ibuprofen inhibits the metabolism of the endogenous cannabimimetic agent anandamide.

C. Fowler, G. Tiger, A. Stenström, 1997, Pharmacology & toxicology.

Effects of water-soluble cigarette smoke extracts upon the release of β-hexosaminidase from RBL-2H3 basophilic leukaemia cells in response to substance P, compound 48/80, concanavalin A and antigen stimulation

C. Fowler, G. Tiger, M. Sandberg, 2003, Inflammation Research.

Pharmacological properties of rat brain fatty acid amidohydrolase in different subcellular fractions using palmitoylethanolamide as substrate.

C. Fowler, G. Tiger, A. Stenström, 2000, Biochemical pharmacology.

Veratrine-Stimulated Phosphoinositide Breakdown as an Assay for Local Anesthetic Actions at Na+ Channels

C. Fowler, G. Tiger, D. Lundin, 1995, Anesthesia and analgesia.

[3H]Imipramine Binding of Protein Nature in Human Platelets: Inhibition by 5‐Hydroxytryptamine and 5‐Hydroxytryptamine Uptake Inhibitors

J. Marcusson, G. Tiger, 1988, Journal of neurochemistry.

Differences in the pharmacological properties of rat and chicken brain fatty acid amidohydrolase

C. Fowler, G. Tiger, Magnus Börjesson, 2000, British journal of pharmacology.

Modulation of receptor-mediated inositol phospholipid breakdown in the brain

C. Fowler, G. Tiger, 1991, Neurochemistry International.

Signal transduction in the brain : modulation of receptor-mediated inositol phospholipid breakdown by potassium and fluoride ions

G. Tiger, 1990 .

Effect of monovalent ions upon G proteins coupling muscarinic receptors to phosphoinositide hydrolysis in the rat cerebral cortex.

R. Cowburn, B. Wiehager, C. Fowler, 1990, European journal of pharmacology.

Selective inhibition of anandamide cellular uptake versus enzymatic hydrolysis--a difficult issue to handle.

V. Di Marzo, M. López-Rodríguez, C. Fowler, 2004, European journal of pharmacology.

Enhancement by Potassium of Carbachol‐Stimulated Inositol Phospholipid Breakdown in Rat Cerebral Cortical Miniprisms: Comparison with Other Depolarising Agents

R. Cowburn, C. Fowler, G. Tiger, 1989, Journal of neurochemistry.

Differential enhancement by potassium ions of M1-type and M2-type muscarinic receptor-mediated phosphoinositide breakdown in the rat brain

C. Fowler, G. Tiger, P. Björklund, 1990, Neuroscience Letters.

Design, synthesis and biological evaluation of new endocannabinoid transporter inhibitors.

J. Ramos, J. Fernández-Ruiz, M. López-Rodríguez, 2003, European journal of medicinal chemistry.

Characterization of the enzymatic activity for biphasic competition by guanoxabenz (1-(2,6-dichlorobenzylidene-amino)-3-hydroxyguanidine) at alpha2-adrenoceptors. I. Description of an enzymatic activity in spleen membranes.

J. Wikberg, G. Tiger, M. Dambrova, 1998, Biochemical pharmacology.

Temporal studies of the inhibition of voluntary ethanol intake in the rat induced by intermittent ethanol treatment and some long term neurochemical consequences.

A. Nordberg, G. Tiger, G. Wahlström, 1991, Drug and alcohol dependence.

Influence of age on effects induced by intermittent ethanol treatment on the ethanol drinking pattern and related neurochemical changes in the rat.

A. Nordberg, C. Fowler, G. Tiger, 1988, Drug and alcohol dependence.

Stimulation of inositol phospholipid breakdown in rat cortical and hippocampal miniprisms by noradrenaline, 5-hydroxytryptamine and carbachol: some methodological aspects.

J. Court, C. Fowler, G. Tiger, 1987, Pharmacology & toxicology.

Impaired performance of rats in the Morris swim-maize test late in abstinence following long-term sodium barbital treatment.

A. Nordberg, T. Archer, A. Mohammed, 1987, Drug and alcohol dependence.

Serotonin-stimulated calcium responses in human platelets: assay buffer dependency.

C. Fowler, G. Tiger, 1998, Cellular signalling.

Neurotoxicity of glutamate in chick telencephalon neurons: reduction of toxicity by preincubation with carbachol, but not by the endogenous fatty acid amides anandamide and palmitoylethanolamide

C. Fowler, G. Tiger, K. Jonsson, 2000, Archives of Toxicology.

Effects of pH on the inhibition of fatty acid amidohydrolase by ibuprofen

C. Fowler, G. Tiger, J. Nilsson, 2001, British journal of pharmacology.

Inhibition of anandamide hydrolysis by the enantiomers of ibuprofen, ketorolac, and flurbiprofen.

R. Johnson, C. Fowler, G. Tiger, 1999, Archives of biochemistry and biophysics.

Multiple actions of fluoride ions upon the phosphoinositide cycle in the rat brain

C. Fowler, G. Tiger, G. Brännström, 1990, Brain Research.

Pharmacological properties of cannabinoid receptors in the avian brain: similarity of rat and chicken cannabinoid1 receptor recognition sites and expression of cannabinoid2 receptor-like immunoreactivity in the embryonic chick brain.

C. Fowler, G. Tiger, G. Disney, 2001, Pharmacology & toxicology.

Serotonin stimulation of calcium mobilisation in human platelets: choice of units of measurement, effects of age and tobacco use, and correlation with serotonin2A receptor density.

C. Fowler, G. Tiger, E. Sjöberg, 1999, Clinica chimica acta; international journal of clinical chemistry.

Calibration of Fura-2 signals introduces errors into measurement of thrombin-stimulated calcium mobilisation in human platelets.

C. Fowler, G. Tiger, 1997, Clinica chimica acta; international journal of clinical chemistry.

Comparison of the Binding Activities of Some Drugs on α2A, α2B and α2C‐Adrenoceptors and Non‐Adrenergic Imidazoline Sites in the Guinea Pig

Staffan Uhlén, Jarl E. S. Wikberg, J. Wikberg, 1995 .

Comparison of the binding activities of some drugs on alpha 2A, alpha 2B and alpha 2C-adrenoceptors and non-adrenergic imidazoline sites in the guinea pig.

J. Wikberg, G. Tiger, R. Muceniece, 1995, Pharmacology & toxicology.

Quantification of alpha2A and alpha2C adrenoceptors in the rat striatum and in different regions of the spinal cord.

J. Wikberg, G. Tiger, J. Lindblom, 1997, Acta physiologica Scandinavica.

Comparison of the effects of hydrogen peroxide, 4-hydroxy-2-nonenal and β-amyloid (25–35) upon calcium signalling

C. Fowler, G. Tiger, Gunnar Tiger, 1998, Neurochemistry International.

Modulation of carbachol-stimulated inositol phospholipid breakdown in rat cerebral cortical miniprisms by excitatory amino acids and by BAY K-8644 is dependent upon the assay calcium and potassium concentrations used.

C. Fowler, G. Tiger, 1991, Life sciences.

Stimulation of inositol phospholipid breakdown in pig brain miniprisms by carbachol and monoamines: effect of K+.

C. Fowler, G. Tiger, P. Björklund, 1989, The International journal of biochemistry.

The sulphydryl oxidizing reagent diamide affects phosphoinositide-mediated signal transduction: implications for the pathogenesis of Alzheimer's disease.

C. Fowler, G. Tiger, 1998, Cellular signalling.

The Na+, K(+)-ATPase inhibitor ouabain and the Na+ ionophore monensin have opposite effects upon carbachol-stimulated inositol phospholipid breakdown in rat cerebral cortical miniprisms.

C. Fowler, G. Tiger, 1991, Cellular signalling.

Further validation of a simple biochemical method for evaluation of local anesthetic effects at sodium channels.

C. Fowler, G. Tiger, 1996, Methods and Findings in Experimental and Clinical Pharmacology.

Comparison of the effects of a series of kappa-opioid receptor agonists upon sodium channel function in rat brain miniprisms.

C. Fowler, G. Tiger, 1997, Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology.

The effects of cyanide on the extracellular levels of dopamine, 3,4-dihydroxyphenylacetic acid, homovanillic acid, 5-hydroxyindoleacetic acid and inositol phospholipid breakdown in the brain.

G. Cassel, G. Tiger, M. Koch, 1995, Neurotoxicology.