M. Corsi

发表

Pharmacological characterization of tachykinin NK2 receptors on isolated human urinary bladder, prostatic urethra and prostate.

S. Palea, M. Corsi, W. Artibani, 1996, The Journal of pharmacology and experimental therapeutics.

Brain reinforcement system function is ghrelin dependent: studies in the rat using pharmacological fMRI and intracranial self‐stimulation

A. Gozzi, A. Bifone, S. Melotto, 2012, Addiction biology.

Cholecystokinin (CCK) Assays

M. Corsi, D. Trist, 1999, Current protocols in pharmacology.

Pharmacological characterization of thromboxane and prostanoid receptors in human isolated urinary bladder

S. Palea, M. Corsi, W. Artibani, 1998, British journal of pharmacology.

Failure of the putative neuropeptide Y antagonists, benextramine and PYX‐2, to inhibit Y2 receptors in rat isolated prostatic vas deferens

J. Rimland, S. Palea, M. Corsi, 1995, British journal of pharmacology.

Analysis of the CCKB receptor antagonism of virginiamycin in guinea‐pig ileum longitudinal myenteric plexus

G. Gaviraghi, M. Corsi, C. Pietra, 1993, British journal of pharmacology.

Pharmacological analysis of 5‐hydroxytryptamine effects on electrically stimulated human isolated urinary bladder

M. Corsi, W. Artibani, C. Pietra, 1991, British journal of pharmacology.

Potentiation of NMDA and AMPA responses by the specific mGluR5 agonist CHPG in spinal cord motoneurons

F. Bordi, M. Corsi, A. Ugolini, 1999, Neuropharmacology.

Estimation of the Relative Potency of Two Glycine Antagonists on NMDA‐induced Depolarizations in BRSC and ARCS

M. Corsi, D. Trist, L. Bettelini, 1997, Annals of the New York Academy of Sciences.

Genomic Organization of the Human Metabotropic Glutamate Receptor Subtype 3

J. Xuereb, F. Ferraguti, C. Corti, 2000, Journal of neurogenetics.

Latest advancements in the pharmacological treatment of binge eating disorder.

D. Marazziti, M. Corsi, S. Baroni, 2012, European review for medical and pharmacological sciences.

Inhibition of the Casein-Kinase-1-Epsilon/Delta Prevents Relapse-Like Alcohol Drinking

R. Spanagel, C. Corti, M. Corsi, 2012, Neuropsychopharmacology.

Atropisomerism and Conformational Equilibria: Impact on PI3Kδ Inhibition of 2-((6-Amino-9H-purin-9-yl)methyl)-5-methyl-3-(o-tolyl)quinazolin-4(3H)-one (IC87114) and Its Conformationally Restricted Analogs.

A. Capelli, M. Mor, M. Corsi, 2017, Journal of medicinal chemistry.

Glutamate receptor mGlu2 and mGlu3 knockout striata are dopamine supersensitive, with elevated D2High receptors and marked supersensitivity to the dopamine agonist (+)PHNO

P. Seeman, C. Corti, G. Battaglia, 2009, Synapse.

Selective Silencing of Individual Dendritic Branches by an mGlu2-Activated Potassium Conductance in Dentate Gyrus Granule Cells

U. Gerber, F. Ferraguti, C. Corti, 2013, The Journal of Neuroscience.

Synthesis and structure-activity relationship of new 1,5-dialkyl-1,5-benzodiazepines as cholecystokinin-2 receptor antagonists.

G. Tedesco, A. Reggiani, R. Barnaby, 2011, Bioorganic & medicinal chemistry.

Synthesis and SAR of new 5-phenyl-3-ureido-1,5-benzodiazepines as cholecystokinin-B receptor antagonists.

A. Capelli, G. Tedesco, G. Gaviraghi, 2000, Journal of medicinal chemistry.

Novel 1,5‐Benzodiazepines as CCK‐B Ligands. Effect of Aryl‐Carbamic Substituents at the C‐3 Position Together with Halogen Substitution on the Benzo‐Fused Ring

G. Tarzia, M. Corsi, D. Donati, 1997, Archiv der Pharmazie.

Synthesis and structure-activity relationship of new 1,5 benzodiazepine CCK-B antagonists

G. Tedesco, G. Gaviraghi, A. Reggiani, 1996 .

Paradoxical response to the sedative effects of diazepam and alcohol in C57BL/6J mice lacking the neuropeptide S receptor

C. Corti, R. Ciccocioppo, M. Corsi, 2014, Peptides.

Role of Orexin-1 Receptor Mechanisms on Compulsive Food Consumption in a Model of Binge Eating in Female Rats

C. Cifani, R. Ciccocioppo, M. Massi, 2012, Neuropsychopharmacology.

Discovery process and pharmacological characterization of a novel dual orexin 1 and orexin 2 receptor antagonist useful for treatment of sleep disorders.

K. Thewlis, E. Chiarparin, Christopher N. Johnson, 2011, Bioorganic & medicinal chemistry letters.

Functional and binding kinetic studies make a distinction between OX1 and OX2 orexin receptor antagonists.

M. Corsi, E. Merlo Pich, R. Di Fabio, 2012, European journal of pharmacology.

Mechanisms of Non-Competitive Antagonism and Co-Agonism

M. Corsi, D. Trist, 2000 .

Discovery Process and Characterization of Novel Carbohydrazide Derivatives as Potent and Selective GHSR1a Antagonists

S. Bromidge, S. Melotto, M. Corsi, 2010, ChemMedChem.

Identification, biological characterization and pharmacophoric analysis of a new potent and selective NK1 receptor antagonist clinical candidate.

Michael K. Trower, R. Carletti, S. Melotto, 2013, Bioorganic & medicinal chemistry.

Potency, efficacy, and selectivity of GR64349 at human recombinant neurokinin NK2 and NK1 receptors

K. Thor, M. Corsi, D. Ricca, 2019, Neuroscience Letters.

Affinity, potency, efficacy, and selectivity of neurokinin A analogs at human recombinant NK2 and NK1 receptors

K. Thor, E. Burgard, M. Corsi, 2018, PloS one.

In vitro and in vivo characterization of the novel GABAB receptor positive allosteric modulator, 2-{1-[2-(4-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]-2-piperidinyl}ethanol (CMPPE)

A. Capelli, M. Corsi, L. Gordon, 2011, Neuropharmacology.

Discovery and biological characterization of (2R,4S)-1'-acetyl-N-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl}-2-(4-fluoro-2-methylphenyl)-N-methyl-4,4'-bipiperidine-1-carboxamide as a new potent and selective neurokinin 1 (NK1) receptor antagonist clinical candidate.

S. Melotto, M. Corsi, D. Montanari, 2011, Journal of medicinal chemistry.

[3H]GR205171 displays similar NK1 receptor binding profile in gerbil and human brain

R. Carletti, M. Corsi, Cristiana Griffante, 2006, British journal of pharmacology.

The mGluR2/3 Agonist LY379268 Induced Anti-Reinstatement Effects in Rats Exhibiting Addiction-like Behavior

R. Spanagel, A. Hansson, C. Corti, 2013, Neuropsychopharmacology.

Azabicyclo[3.1.0]hexane‐1‐carbohydrazides as Potent and Selective GHSR1a Ligands Presenting a Specific in vivo Behavior

S. Bromidge, S. Melotto, M. Corsi, 2011, ChemMedChem.

Discovery process and pharmacological characterization of 2-(S)-(4-fluoro-2-methylphenyl)piperazine-1-carboxylic acid [1-(R)-(3,5-bis-trifluoromethylphenyl)ethyl]methylamide (vestipitant) as a potent, selective, and orally active NK1 receptor antagonist.

S. Melotto, M. Corsi, D. Montanari, 2009, Journal of medicinal chemistry.

Synthesis and pharmacological characterization of constrained analogues of Vestipitant as in vitro potent and orally active NK(1) receptor antagonists.

A. Capelli, S. Melotto, M. Corsi, 2010, Bioorganic & medicinal chemistry letters.

Discrimination by benextramine between the NPY‐Y1 receptor subtypes present in rabbit isolated vas deferens and saphenous vein

J. Rimland, S. Palea, M. Corsi, 1995, British journal of pharmacology.

Different Levels of Receptor Expression as a New Procedure to Estimate Agonist Affinity Constant

F. Ferraguti, C. Corti, M. Corsi, 1997, Annals of the New York Academy of Sciences.

Spontaneous preference for ethanol in naive rats is influenced by cholecystokinin A receptor antagonism.

G. Gaviraghi, M. Corsi, F. Crespi, 1997, Alcohol.

Structure-Activity Studies on Neuropeptide S

S. Salvadori, C. Corti, G. Calo’, 2006, Journal of Biological Chemistry.

Identification and characterization of the promoter region of the GRM3 gene.

J. Xuereb, F. Ferraguti, C. Corti, 2001, Biochemical and biophysical research communications.

Activation of the extracellular signal‐regulated kinase 2 by metabotropic glutamate receptors

S. Nakanishi, F. Ferraguti, C. Corti, 1999, The European journal of neuroscience.

Potentiation of NMDA and AMPA responses by group I mGluR in spinal cord motoneurons

F. Bordi, M. Corsi, A. Ugolini, 1997, Neuropharmacology.

Manganese-enhanced magnetic resonance imaging investigation of the interferon-α model of depression in rats.

Angelo Bifone, Alessandro Daducci, Andrea Sbarbati, 2014, Magnetic resonance imaging.

Effects of antidepressant drugs and GR 205171, an neurokinin-1 (NK1) receptor antagonist, on the response in the forced swim test and on monoamine extracellular levels in the frontal cortex of the mouse

M. Corsi, M. Marchi, L. Bettelini, 2003, Neuroscience Letters.

UPREGULATION OF SPINAL GLUTAMATE RECEPTORS IN CHRONIC PAIN

M. Bentivoglio, M. Corsi, J. A. Harris, 1996, Neuroscience.

Bidirectional Regulation of Neurite Elaboration by Alternatively Spliced Metabotropic Glutamate Receptor 5 (mGluR5) Isoforms

R. Shigemoto, F. Ferraguti, C. Corti, 2001, Molecular and Cellular Neuroscience.

Allosteric modulation of [3H]‐CGP39653 binding through the glycine site of the NMDA receptor: further studies in rat and human brain

N. Bowery, M. Corsi, M. Mugnaini, 2001, British journal of pharmacology.

Discrimination bybenextramine between theNPY-Y1receptor subtypes present inrabbit isolated vas deferens andsaphenous vein

J. Rimland, M. Corsi, D. Trist, 1995 .

Neurokinin 1 receptor and relative abundance of the short and long isoforms in the human brain

Y. Hurd, P. Murdock, R. Carletti, 2003, The European journal of neuroscience.

Neuroimaging Evidence of Altered Fronto-Cortical and Striatal Function after Prolonged Cocaine Self-Administration in the Rat

Angelo Bifone, Alessandro Gozzi, Federica Agosta, 2011, Neuropsychopharmacology.

Cloning and characterization of alternative mRNA forms for the rat metabotropic glutamate receptors mGluR7 and mGluR8

F. Ferraguti, J. Pin, I. Brabet, 1998, The European journal of neuroscience.

The CaV3.3 calcium channel is the major sleep spindle pacemaker in thalamus

Ralf D Wimmer, Paul Franken, Andrea Volterra, 2011, Proceedings of the National Academy of Sciences.

Drug discovery for the treatment of substance use disorders: novel targets, repurposing, and the need for new paradigms

C. Chiamulera, L. Padovani, M. Corsi, 2017, Current opinion in pharmacology.

The Use of Knock-Out Mice Unravels Distinct Roles for mGlu2 and mGlu3 Metabotropic Glutamate Receptors in Mechanisms of Neurodegeneration/Neuroprotection

F. Nicoletti, A. Pittaluga, C. Corti, 2007, The Journal of Neuroscience.

Down‐regulation of amygdala preprotachykinin A mRNA but not 3H‐SP receptor binding sites in subjects affected by mood disorders and schizophrenia

R. Carletti, S. Melotto, M. Corsi, 2005, The European journal of neuroscience.

Receptor binding characteristics of the novel NMDA receptor glycine site antagonist [3H]GV150526A in rat cerebral cortical membranes.

M. Corsi, M. Mugnaini, B. Bunnemann, 2000, European journal of pharmacology.

GV196771A, an NMDA receptor/glycine site antagonist, attenuates mechanical allodynia in neuropathic rats and reduces tolerance induced by morphine in mice.

M. Corsi, L. Bettelini, N. Fasdelli, 2001, European journal of pharmacology.

Differential Effects of the CRF-R1 Antagonist GSK876008 on Fear-Potentiated, Light- and CRF-Enhanced Startle Suggest Preferential Involvement in Sustained versus Phasic Threat Responses

M. Davis, D. Walker, M. Corsi, 2008, Neuropsychopharmacology.

Activation of mGlu3 Receptors Stimulates the Production of GDNF in Striatal Neurons

N. Belluardo, F. Nicoletti, V. Di Liberto, 2009, PloS one.

[3H]5,7-dichlorokynurenic acid recognizes two binding sites in rat cerebral cortex membranes.

M. Corsi, M. Mugnaini, F. V. van Amsterdam, 1998, Journal of receptor and signal transduction research.

Inhibition of glycine transporter‐1 reduces cue‐induced nicotine‐seeking, but does not promote extinction of conditioned nicotine cue responding in the rat

E. Pich, L. Cervo, A. Gozzi, 2013, Addiction biology.

Application of an "inhalation by design" approach to the identification and in-vitro evaluation of novel purine based PI3Kδ inhibitors.

A. Capelli, M. Corsi, M. Roberti, 2023, European journal of medicinal chemistry.

Synthesis and pharmacological characterisation of 2,4-dicarboxy-pyrroles as selective non-competitive mGluR1 antagonists.

C. Chiamulera, A. Capelli, F. Ferraguti, 2003, Bioorganic & medicinal chemistry.

Reinforcing and locomotor stimulant effects of cocaine are absent in mGluR5 null mutant mice

F. Conquet, C. Chiamulera, F. Orzi, 2001, Nature Neuroscience.

Anxiolytic-like effects of the neurokinin 1 receptor antagonist GR-205171 in the elevated plus maze and contextual fear-potentiated startle model of anxiety in gerbils

Michael Davis, K. Ressler, M. Corsi, 2009, Behavioural pharmacology.

GSK1614343, a Novel Ghrelin Receptor Antagonist, Produces an Unexpected Increase of Food Intake and Body Weight in Rodents and Dogs

S. Melotto, M. Corsi, M. Tessari, 2011, Neuroendocrinology.

6-(3,4-dichlorophenyl)-1-[(methyloxy)methyl]-3-azabicyclo[4.1.0]heptane: a new potent and selective triple reuptake inhibitor.

K. Read, G. Tedesco, R. Carletti, 2010, Journal of medicinal chemistry.

Altered levels of glutamatergic receptors and Na+/K+ ATPase-α1 in the prefrontal cortex of subjects with schizophrenia

L. Crepaldi, J. Xuereb, F. Ferraguti, 2011, Schizophrenia Research.

The relative importance of the time-course of receptor occupancy and response decay on apparent antagonist potency in dynamic assays.

T. Kenakin, M. Corsi, 2000, Journal of autonomic pharmacology.

Combined treatment with a selective PDE10A inhibitor TAK‐063 and either haloperidol or olanzapine at subeffective doses produces potent antipsychotic‐like effects without affecting plasma prolactin levels and cataleptic responses in rodents

M. Corsi, A. Ugolini, Clizia Capuani, 2017, Pharmacology research & perspectives.

Evidence for the presence of both pre‐ and postjunctional P2‐purinoceptor subtypes in human isolated urinary bladder

S. Palea, M. Corsi, W. Artibani, 1995, British journal of pharmacology.

Co-agonism in drug-receptor interaction: illustrated by the NMDA receptors.

M. Corsi, D. Trist, P. Fina, 1996, Trends in pharmacological sciences.

Pharmacological characterization of the ghrelin receptor antagonist, GSK1614343 in rat RC-4B/C cells natively expressing GHS type 1a receptors.

C. Corti, M. Corsi, E. Perdona', 2011, European journal of pharmacology.

Inhibition of SK3 channels in the TE671 human medulloblastoma cell line by desipramine and imipramine.

M. Corsi, C. Carignani, 2002, European journal of pharmacology.

Functional Magnetic Resonance Imaging Reveals Different Neural Substrates for the Effects of Orexin-1 and Orexin-2 Receptor Antagonists

Angelo Bifone, Alessandro Gozzi, Dino Montanari, 2011, PloS one.

Functional magnetic resonance mapping of intracerebroventricular infusion of a neuroactive peptide in the anaesthetised rat

Angelo Bifone, Alessandro Gozzi, Adam J. Schwarz, 2005, Journal of Neuroscience Methods.

Potent antihyperalgesic activity without tolerance produced by glycine site antagonist of N-methyl-D-aspartate receptor GV196771A.

A. Reggiani, F. Belardetti, M. Corsi, 1999, The Journal of pharmacology and experimental therapeutics.

rKv1.2 overexpression in the central medial thalamic area decreases caffeine‐induced arousal

A. Lüthi, C. Corti, Z. Rovó, 2011, Genes, brain, and behavior.

Regulation of Group II Metabotropic Glutamate Receptors by G Protein-Coupled Receptor Kinases: mGlu2 Receptors Are Resistant to Homologous Desensitization

F. Nicoletti, C. Corti, G. Battaglia, 2009, Molecular Pharmacology.

Chiral tetrahydroquinoline derivatives as potent anti-hyperalgesic agents in animal models of sustained inflammation and chronic neuropathic pain.

R. Barnaby, M. Corsi, E. Ratti, 2007, Bioorganic & medicinal chemistry letters.

Enhancement of CA3 hippocampal network activity by activation of group II metabotropic glutamate receptors

Benjamin F. Grewe, F. Helmchen, U. Gerber, 2011, Proceedings of the National Academy of Sciences.

GV 196771A, a New Glycine Site Antagonist of the NMDA Receptor with Potent Antihyperalgesic Activity

M. Corsi, M. Mugnaini, D. Trist, 2003 .

Short Communication Glutamate Receptor mGlu2 and mGlu3 Knockout Striata are Dopamine Supersensitive, With Elevated D2 High Receptors and Marked Supersensitivity to the Dopamine Agonist (1)PHNO

P. Seeman, C. Corti, G. Battaglia, 2009 .

Discovery of Pyrazolo[1,5-a]pyrazin-4-ones as Potent and Brain Penetrant GluN2A-Selective Positive Allosteric Modulators Reducing AMPA Receptor Binding Activity.

Tomoaki Hasui, M. Corsi, M. Kamata, 2021, Bioorganic & medicinal chemistry.

IN RAT CEREBRAL CORTEX MEMBRANES

M. Corsi, M. Mugnaini, M. Antolini, 1998 .

Individual contribution of metabotropic glutamate receptor (mGlu) 2 and 3 to c-Fos expression pattern evoked by mGlu2/3 antagonism

F. Ferraguti, C. Corti, N. Singewald, 2008, Psychopharmacology.

Design and synthesis of 6-methylpyridin-2-one derivatives as novel and potent GluN2A positive allosteric modulators for the treatment of cognitive impairment.

Tomoaki Hasui, M. Corsi, H. Kakei, 2022, Bioorganic & medicinal chemistry.

Synergistic effects of cAMP-dependent signalling pathways and IL-1 on IL-6 production by H19-7/IGF-IR neuronal cells.

A. Bergamaschi, M. Corsi, M. Garnier, 2006, Cellular signalling.

Inhibition of glycine transporter‐1 reduces cue‐induced nicotine‐seeking, but does not promote extinction of conditioned nicotine cue responding in the rat

E. Pich, L. Cervo, A. Gozzi, 2013, Addiction biology.

ADP beta S induces contraction of the human isolated urinary bladder through a purinoceptor subtype different from P2X and P2Y.

G. Gaviraghi, S. Palea, M. Corsi, 1994, The Journal of pharmacology and experimental therapeutics.

AMN082, an allosteric mGluR7 agonist that inhibits afferent glutamatergic transmission in rat basolateral amygdala

C. Large, M. Corsi, A. Ugolini, 2008, Neuropharmacology.