D. Grieve

发表

Diabetic Nephropathy: a Tangled Web to Unweave

D. Brazil, C. Magee, D. Grieve, 2017, Cardiovascular Drugs and Therapy.

Endothelial NADPH oxidase-2 promotes interstitial cardiac fibrosis and diastolic dysfunction through proinflammatory effects and endothelial-mesenchymal transition.

Simon J. Walker, S. Heymans, A. Shah, 2014, Journal of the American College of Cardiology.

Endothelial Nox4 NADPH Oxidase Enhances Vasodilatation and Reduces Blood Pressure In Vivo

Philip Eaton, Robin Ray, Simon J. Walker, 2011, Arteriosclerosis, thrombosis, and vascular biology.

Role of oxidative stress in cardiac remodelling after myocardial infarction.

A. Shah, D. Grieve, J. Byrne, 2004, Heart, lung & circulation.

Essential role of troponin I in the positive inotropic response to isoprenaline in mouse hearts contracting auxotonically

A. Shah, A. Shah, D. Grieve, 2004, The Journal of physiology.

Role of A Novel Angiogenesis FKBPL-CD44 Pathway in Preeclampsia Risk Stratification and Mesenchymal Stem Cell Treatment

I. Young, L. Kenny, V. Garovic, 2020, The Journal of clinical endocrinology and metabolism.

NADPH oxidase and heart failure.

A. Shah, D. Grieve, A. Cave, 2006, Current opinion in pharmacology.

NADPH oxidase-derived reactive oxygen species in cardiac pathophysiology

Min Zhang, A. Shah, D. Grieve, 2005, Philosophical Transactions of the Royal Society B: Biological Sciences.

The RNA-binding protein QKI controls alternative splicing in vascular cells, producing an effective model for therapy

Alan W. Stitt, D. Grieve, Chunbo Yang, 2019, Journal of Cell Science.

Enhanced Function of Induced Pluripotent Stem Cell‐Derived Endothelial Cells Through ESM1 Signaling

A. Zampetaki, Alan W. Stitt, R. Medina, 2018, Stem cells.

Involvement of Nox2 NADPH Oxidase in Adverse Cardiac Remodeling After Myocardial Infarction

Simon J. Walker, A. Shah, M. Marber, 2008, Hypertension.

Involvement of Nox 2 NADPH Oxidase in Adverse Cardiac Remodeling After Myocardial Infarction

Simon J. Walker, A. Shah, M. Marber, 2008 .

Oxidative stress in heart failure. More than just damage.

A. Shah, D. Grieve, 2003, European heart journal.

Analysis of ex vivo left ventricular pressure–volume relations in the isolated murine ejecting heart

A. Shah, D. Grieve, J. Byrne, 2004, Experimental physiology.

Treatment of lean and diet-induced obesity (DIO) mice with a novel stable obestatin analogue alters plasma metabolite levels as detected by untargeted LC–MS metabolomics

B. Green, D. Grieve, S. Graham, 2016, Metabolomics.

The gastrointestinal peptide obestatin induces vascular relaxation via specific activation of endothelium‐dependent NO signalling

A. Harvey, B. Green, D. Grieve, 2012, British journal of pharmacology.

Vascular endothelial function and blood pressure homeostasis in mice overexpressing IGF binding protein-1.

A. Shah, M. Kearney, D. Grieve, 2003, Diabetes.

Nox2 NADPH oxidase promotes pathologic cardiac remodeling associated with Doxorubicin chemotherapy.

A. Shah, A. Harvey, D. Grieve, 2010, Cancer research.

Selective targeting of glucagon‐like peptide‐1 signalling as a novel therapeutic approach for cardiovascular disease in diabetes

M. Tate, B. Green, D. Grieve, 2015, British journal of pharmacology.

Reactive oxygen species signalling in the diabetic heart: emerging prospect for therapeutic targeting

A. J. Wilson, D. Grieve, C. Watson, 2017, Heart.

NOX 4 is a major regulator of cord blood-derived endothelial colony-forming cells which promotes post-ischaemic revascularization

Alan W. Stitt, M. Yoder, R. Medina, 2019 .

NOX4 is a major regulator of cord blood-derived endothelial colony-forming cells which promotes postischaemic revascularisation.

Alan W. Stitt, M. Yoder, R. Medina, 2019, Cardiovascular research.

FKBPL and SIRT-1, key angiogenesis proteins, are downregulated by diabetes in pregnancy

I. Young, D. Grieve, C. Watson, 2020, medRxiv.

Strain-dependent variation in vascular responses to nitric oxide in the isolated murine heart.

A. Shah, D. Grieve, A. Cave, 2002, Journal of molecular and cellular cardiology.

Leptin is an endothelial-independent vasodilator in humans with coronary artery disease: Evidence for tissue specificity of leptin resistance.

A. Shah, M. Kearney, D. Grieve, 2006, European heart journal.

Divergent Biological Actions of Coronary Endothelial Nitric Oxide During Progression of Cardiac Hypertrophy

A. Shah, D. Grieve, P. MacCarthy, 2001, Hypertension.

Impaired Endothelial Regulation of Ventricular Relaxation in Cardiac Hypertrophy: Role of Reactive Oxygen Species and NADPH Oxidase

F. Kelly, Jian-Mei Li, D. Grieve, 2001, Circulation.

The Interaction between Oxidised Chylomicron Remnants and the Aorta of Rats Fed a Normocholesterolaemic or Hypercholesterolaemic Diet

D. Grieve, J. Elliott, M. Avella, 2000, Journal of Vascular Research.

The influence of chylomicron remnants on endothelial cell function in the isolated perfused rat aorta.

D. J. Grieve, D. Grieve, J. Elliott, 1998, Atherosclerosis.

Follistatin‐Like 3 Enhances the Function of Endothelial Cells Derived from Pluripotent Stem Cells by Facilitating β‐Catenin Nuclear Translocation Through Inhibition of Glycogen Synthase Kinase‐3β Activity

Alan W. Stitt, C. Magee, D. Grieve, 2018, Stem cells.

Adult cardiac fibroblast proliferation is modulated by calcium/calmodulin-dependent protein kinase II in normal and hypertrophied hearts

R. Plevin, D. Grieve, E. Robinson, 2013, Pflügers Archiv - European Journal of Physiology.

Effects of chylomicrons and chylomicron remnants on endothelium-dependent relaxation of rat aorta.

D. Grieve, J. Elliott, M. Avella, 1998, European journal of pharmacology.

Surgical optimization and characterization of a minimally invasive aortic banding procedure to induce cardiac hypertrophy in mice

D. Grieve, E. Robinson, S. Currie, 2012, Experimental physiology.

Metabolically-inactive glucagon-like peptide-1(9–36)amide confers selective protective actions against post-myocardial infarction remodelling

M. Tate, B. Green, D. Grieve, 2016, Cardiovascular Diabetology.

Exendin-4 attenuates adverse cardiac remodelling in streptozocin-induced diabetes via specific actions on infiltrating macrophages

M. Tate, B. Green, D. Grieve, 2015, Basic Research in Cardiology.

Protection against endotoxemia‐induced contractile dysfunction in mice with cardiac‐specific expression of slow skeletal troponin I

A. Shah, D. Grieve, R. Solaro, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Conformational change of mitochondrial complex I increases ROS sensitivity during ischemia.

D. Grieve, E. Robinson, A. Galkin, 2013, Antioxidants & redox signaling.

NADPH Oxidase-4 Driven Cardiac Macrophage Polarization Protects Against Myocardial Infarction–Induced Remodeling

Alberto Smith, Min Zhang, A. Shah, 2017, JACC. Basic to translational science.

NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis

Simon J. Walker, A. Shah, R. Brandes, 2010, Proceedings of the National Academy of Sciences.

Loss of TRPV2-mediated blood flow autoregulation recapitulates diabetic retinopathy in rats

T. Curtis, Alan W. Stitt, P. Barabas, 2022, JCI insight.

The influence of vestibular stimulation on metabolism and body composition

P. McGeoch, D. Grieve, J. McKeown, 2019, Diabetic medicine : a journal of the British Diabetic Association.

Impaired Function in Diabetic Patient iPSCs-derived Blood Vessel Organoids Stem from a Subpopulation of Vascular Cells

A. Zampetaki, P. Dunne, D. Grieve, 2022, bioRxiv.

A Nox2-containing NADPH oxidase contributes to cardiac remodeling after myocardial infarction

Simon J. Walker, A. Shah, D. Grieve, 2005 .

Signalling mechanisms underlying doxorubicin and Nox2 NADPH oxidase‐induced cardiomyopathy: involvement of mitofusin‐2

P. Dunne, D. Grieve, B. McDermott, 2017, British journal of pharmacology.

Contrasting Roles of NADPH Oxidase Isoforms in Pressure-Overload Versus Angiotensin II–Induced Cardiac Hypertrophy

A. Shah, Jian-Mei Li, J. Lambeth, 2003, Circulation research.

Chylomicron remnants potentiate phenylephrine-induced contractions of rat aorta by an endothelium-dependent mechanism.

D. Grieve, J. Elliott, M. Avella, 2000, Atherosclerosis.

In Vitro and In Vivo Effects of Natural Putative Secretagogues of Glucagon-Like Peptide-1 (GLP-1)

C. Elliott, O. Chevallier, B. Green, 2011, Scientia pharmaceutica.

GSTM1 Modulates Expression of Endothelial Adhesion Molecules in Uremic Milieu

T. Simić, D. Grieve, A. Alqudah, 2021, Oxidative medicine and cellular longevity.

NADPH oxidases in cardiovascular health and disease.

Simon J. Walker, A. Shah, D. Grieve, 2006, Antioxidants & redox signaling.

Epigenetic Regulation of Endothelial Cell Function by Nucleic Acid Methylation in Cardiac Homeostasis and Disease

D. Grieve, C. Watson, A. Russell-Hallinan, 2020, Cardiovascular Drugs and Therapy.

Quaking Is a Key Regulator of Endothelial Cell Differentiation, Neovascularization, and Angiogenesis

Qingbo Xu, Alan W. Stitt, C. Magee, 2017, Stem cells.

Aldosterone mediates angiotensin II‐induced interstitial cardiac fibrosis via a Nox2‐containing NADPH oxidase

A. Shah, D. Grieve, A. Cave, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Blood pressure and vascular endothelial function in transgenic mice with overexpression of insulin-like growth factor binding protein (IGFBP)-1

A. Shah, M. Kearney, D. Grieve, 2002 .

Significance of peroxisome proliferator-activated receptors in the cardiovascular system in health and disease.

D. Grieve, E. Robinson, 2009, Pharmacology & therapeutics.

Activation of NADPH Oxidase During Progression of Cardiac Hypertrophy to Failure

A. Shah, Jian-Mei Li, D. Grieve, 2002, Hypertension.

Adult cardiac fibroblast proliferation is modulated by calcium/calmodulin-dependent protein kinase II in normal and hypertrophied hearts

R. Plevin, D. Grieve, E. Robinson, 2014, Pflügers Archiv - European Journal of Physiology.

The association between saphenous vein endothelial function, systemic inflammation, and statin therapy in patients undergoing coronary artery bypass surgery.

A. Shah, M. Kearney, D. Grieve, 2007, The Journal of thoracic and cardiovascular surgery.

Targeting QKI-7 in vivo restores endothelial cell function in diabetes

A. Zampetaki, Alan W. Stitt, D. Grieve, 2020, Nature Communications.

Are targeted therapies for diabetic cardiomyopathy on the horizon?

M. Tate, R. Ritchie, D. Grieve, 2017, Clinical science.

Exendin-4 protects against post-myocardial infarction remodelling via specific actions on inflammation and the extracellular matrix

Youyou Zhao, Barbara J. McDermott, Mary K. McGahon, 2015, Basic Research in Cardiology.

The RNA binding protein QKI controls alternative splicing as a model of vascular therapies.

Alan W. Stitt, D. Grieve, Chunbo Yang, 2019, Journal of cell science.

Cardiac sub-volume targeting demonstrates regional radiosensitivity in the mouse heart.

M. V. van Herk, M. Aznar, A. McWilliam, 2020, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Emerging cardiovascular actions of the incretin hormone glucagon‐like peptide‐1: potential therapeutic benefits beyond glycaemic control?

B. Green, D. Grieve, R. Cassidy, 2009, British journal of pharmacology.

Obestatin as a key regulator of metabolism and cardiovascular function with emerging therapeutic potential for diabetes

B. Green, D. Grieve, E. Cowan, 2016, British journal of pharmacology.

B. Green, D. Grieve, Roslyn S. Cassidy, 2008, Archives of biochemistry and biophysics.

Downregulation of PPARα during Experimental Left Ventricular Hypertrophy is Critically Dependent on Nox2 NADPH Oxidase Signalling

P. Dunne, A. Harvey, D. Grieve, 2020, International journal of molecular sciences.

Involvement of the nicotinamide adenosine dinucleotide phosphate oxidase isoform Nox2 in cardiac contractile dysfunction occurring in response to pressure overload.

A. Shah, D. Grieve, A. Siva, 2006, Journal of the American College of Cardiology.

Divergent effects of a Nox2-containing NADPH oxidase on cardiac contractile function and hypertrophy after imposition of chronic pressure overload

A. Shah, D. Grieve, A. Siva, 2004 .

FKBPL and SIRT-1 Are Downregulated by Diabetes in Pregnancy Impacting on Angiogenesis and Endothelial Function

I. Young, D. Grieve, C. Watson, 2021, Frontiers in Endocrinology.

Investigating the effects of physiological bile acids on GLP-1 secretion and glucose tolerance in normal and GLP-1R-/- mice

B. Green, D. Grieve, C. E. Elliott, 2011, Biological chemistry.

FKBPL, a novel player in cardiac ischaemia and fibrosis

D. Grieve, B. Rayner, A. Alqudah, 2020 .

Biochemical properties and biological actions of obestatin and its relevence in type 2 diabetes

B. Green, D. Grieve, 2018, Peptides.

Targeted Mobilisation of Endogenous Endothelial Progenitor Cells - an Alternate Approach to Allogeneic Therapy for Ischaemic Cardiovasular Disease?

D. Grieve, Karla M. O’Neill, 2023, Cardiovascular drugs and therapy.

Refinement of a mouse cardiovascular model : Development , application and dissemination

D. Grieve, 2019 .

Endothelial Cells Derived From Patients With Diabetic Macular Edema Recapitulate Clinical Evaluations of Anti-VEGF Responsiveness Through the Neuronal Pentraxin 2 Pathway

Alan W. Stitt, G. Virgili, D. Grieve, 2020, Diabetes.

Author Correction: Targeting QKI-7 in vivo restores endothelial cell function in diabetes

A. Zampetaki, Alan W. Stitt, D. Grieve, 2020, Nature Communications.

NADPH Oxidase-4 Driven Cardiac Macrophage Polarization Protects Against Myocardial Infarction–Induced Remodeling

Alberto Smith, Min Zhang, A. Shah, 2017, JACC. Basic to translational science.

NADPH oxidase-derived reactive oxygen species in cardiac pathophysiology.

Min Zhang, A. Shah, D. Grieve, 2005, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

A gp91-phox-containing NADPH oxidase is critical for angiotensin II-induced interstitial cardiac fibrosis

A. Shah, D. Grieve, A. Cave, 2004 .

ECSIT is a critical limiting factor for cardiac function

D. Stolz, D. Grieve, C. Watson, 2021, JCI insight.

Endothelial Nox4 NADPH Oxidase Enhances Vasodilatation and Reduces Blood Pressure In Vivo

Simon J. Walker, A. Shah, D. Grieve, 2011, Arteriosclerosis, thrombosis, and vascular biology.

Involvement of Nox2 NADPH Oxidase in Adverse Cardiac Remodeling After Myocardial Infarction

Simon J. Walker, A. Shah, M. Marber, 2008, Hypertension.

Signalling mechanisms underlying doxorubicin and Nox2 NADPH oxidase‐induced cardiomyopathy: involvement of mitofusin‐2

P. Dunne, D. Grieve, B. McDermott, 2017, British journal of pharmacology.

Conformational change of mitochondrial complex I increases ROS sensitivity during ischemia.

D. Grieve, E. Robinson, A. Galkin, 2013, Antioxidants & redox signaling.

Surgical optimization and characterization of a minimally invasive aortic banding procedure to induce cardiac hypertrophy in mice

D. Grieve, E. Robinson, S. Currie, 2012, Experimental physiology.

Nox2 NADPH oxidase promotes pathologic cardiac remodeling associated with Doxorubicin chemotherapy.

A. Shah, A. Harvey, D. Grieve, 2010, Cancer research.

Quaking Is a Key Regulator of Endothelial Cell Differentiation, Neovascularization, and Angiogenesis

Qingbo Xu, Alan W. Stitt, C. Magee, 2017, Stem cells.

Obestatin as a key regulator of metabolism and cardiovascular function with emerging therapeutic potential for diabetes

B. Green, D. Grieve, E. Cowan, 2016, British journal of pharmacology.

Vascular endothelial function and blood pressure homeostasis in mice overexpressing IGF binding protein-1.

A. Shah, M. Kearney, D. Grieve, 2003, Diabetes.

Nox2 NADPH oxidase promotes pathologic cardiac remodeling associated with Doxorubicin chemotherapy.

A. Shah, D. Grieve, E. Robinson, 2010, Cancer research.

New insights into cardiotoxicity caused by chemotherapeutic agents

S. Davidson, D. Grieve, 2017, British journal of pharmacology.