S. Oikawa

发表

Repetitive Glucose Spikes Accelerate Atherosclerotic Lesion Formation in C57BL/6 Mice

H. Sugihara, Y. Shuto, A. Asai, 2015, PloS one.

Sitagliptin Improves Plasma Apolipoprotein Profile in Type 2 Diabetes: A Randomized Clinical Trial of Sitagliptin Effect on Lipid and Glucose Metabolism (SLIM) Study.

J. Sasaki, S. Kono, H. Sugihara, 2020, Diabetes research and clinical practice.

Etiology of hypercholesterolemia in patients with anorexia nervosa.

S. Oikawa, Rina Ohwada, M. Hotta, 2006, The International journal of eating disorders.

Evaluation of right adrenal vein cannulation by computed tomography angiography in 140 consecutive patients undergoing adrenal venous sampling.

H. Sugihara, S. Oikawa, S. Kumita, 2014, European journal of endocrinology.

Adherence to Diabetes Self-Management Practices among Type Ii Diabetic Patients in Ethiopia; A Cross Sectional Study

S. Oikawa, 2013 .

Waist Circumference as a Cardiovascular and Metabolic Risk in Japanese Patients With Type 2 Diabetes

Y. Yamasaki, Y. Ohashi, H. Sone, 2009, Obesity.

Impact of lipoprotein glomerulopathy on the relationship between lipids and renal diseases.

S. Oikawa, A. Matsunaga, Takao Saito, 2006, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Association of a Novel 3-Amino Acid Deletion Mutation of Apolipoprotein E (Apo E Tokyo) with Lipoprotein Glomerulopathy

T. Saruta, J. Sasaki, S. Oikawa, 1999, Nephron.

A novel apolipoprotein E mutation, E2 (Arg25Cys), in lipoprotein glomerulopathy.

T. Kita, J. Sasaki, K. Arakawa, 1999, Kidney international.

A novel 18-amino acid deletion in apolipoprotein E associated with lipoprotein glomerulopathy.

J. Sasaki, K. Uchida, S. Oikawa, 1999, Kidney international.

Apolipoprotein E Sendai (arginine 145-->proline): a new variant associated with lipoprotein glomerulopathy.

J. Sasaki, H. Jingami, S. Oikawa, 1997, Journal of the American Society of Nephrology : JASN.

Effect of glucose concentration on foam cell formation in THP-1 cells.

S. Oikawa, T. Toyota, K. Hayasaka, 2001, Journal of atherosclerosis and thrombosis.

Diversity of molecular forms of plasma brain natriuretic peptide in heart failure—different proBNP-108 to BNP-32 ratios in atrial and ventricular overload

T. Ishimitsu, N. Minamino, T. Ieiri, 2009, Heart.

Special Report Guidelines for the Management of Familial Hypercholesterolemia

S. Yamashita, T. Okamura, H. Arai, 2012 .

The change in low-density lipoprotein cholesterol concentration is positively related to plasma docosahexaenoic acid but not eicosapentaenoic acid.

Y. Matsuzawa, K. Shimada, M. Matsuzaki, 2012, Journal of atherosclerosis and thrombosis.

Management of type IIb dyslipidemia.

S. Yamashita, H. Sone, H. Arai, 2012, Journal of atherosclerosis and thrombosis.

Amadori‐glycated phosphatidylethanolamine induces angiogenic differentiations in cultured human umbilical vein endothelial cells

K. Nakagawa, S. Oikawa, T. Miyazawa, 2003, FEBS letters.

Characterization of Pancreatic Islets in Two Selectively Bred Mouse Lines with Different Susceptibilities to High-Fat Diet-Induced Glucose Intolerance

S. Yagihashi, H. Sugihara, Y. Shuto, 2014, PloS one.

ACTH stimulation test and computed tomography are useful for differentiating the subtype of primary aldosteronism.

H. Tamura, H. Sugihara, Mototsugu Nagao, 2017, Endocrine journal.

Relationship Between Coronary Events and Serum Cholesterol During 10 Years of Low-Dose Simvastatin Therapy

Y. Matsuzawa, K. Shimamoto, M. Matsuzaki, 2008 .

Distinct effects of pravastatin, atorvastatin, and simvastatin on insulin secretion from a beta-cell line, MIN6 cells.

H. Shimano, N. Yamada, S. Oikawa, 2006, Journal of atherosclerosis and thrombosis.

Sustained reduction of serum cholesterol in low-dose 6-year simvastatin treatment with minimum side effects in 51,321 Japanese hypercholesterolemic patients.

Y. Matsuzawa, K. Shimamoto, M. Matsuzaki, 2003, Circulation journal : official journal of the Japanese Circulation Society.

Elevation of HDL-C in response to statin treatment is involved in the regression of carotid atherosclerosis.

S. Kono, H. Katagiri, Y. Oka, 2014, Journal of atherosclerosis and thrombosis.

Primary Cardiovascular Events and Serum Lipid Levels in Elderly Japanese with Hypercholesterolemia Undergoing 6‐Year Simvastatin Treatment: A Subanalysis of the Japan Lipid Intervention Trial

Y. Matsuzawa, K. Shimamoto, M. Matsuzaki, 2004, Journal of the American Geriatrics Society.

Large scale cohort study of the relationship between serum cholesterol concentration and coronary events with low-dose simvastatin therapy in Japanese patients with hypercholesterolemia and coronary heart disease: secondary prevention cohort study of the Japan Lipid Intervention Trial (J-LIT).

Y. Matsuzawa, K. Shimamoto, M. Matsuzaki, 2002, Circulation journal : official journal of the Japanese Circulation Society.

Design and baseline characteristics of a cohort study in Japanese patients with hypercholesterolemia: the Japan lipid intervention trial (J-LIT)

Y. Matsuzawa, K. Shimamoto, M. Matsuzaki, 2000 .

S. Oikawa, M. Kinoshita, T. Miyazawa, 2000, Clinical chemistry.

Dietary isohumulones, the bitter components of beer, raise plasma HDL-cholesterol levels and reduce liver cholesterol and triacylglycerol contents similar to PPARalpha activations in C57BL/6 mice.

K. Kondo, S. Oikawa, Y. Miura, 2005, The British journal of nutrition.

Transgenerational changes of metabolic phenotypes in two selectively bred mouse colonies for different susceptibilities to diet-induced glucose intolerance.

H. Sugihara, A. Asai, Mototsugu Nagao, 2015, Endocrine journal.

International clinical harmonization of glycated hemoglobin in Japan: From Japan Diabetes Society to National Glycohemoglobin Standardization Program values

T. Sanke, M. Noda, T. Hanafusa, 2012, Diabetology International.

Preventive effects of eicosapentaenoic acid on coronary artery disease in patients with peripheral artery disease.

Y. Matsuzawa, K. Shimada, M. Matsuzaki, 2010, Circulation journal : official journal of the Japanese Circulation Society.

The new worldwide definition of metabolic syndrome is not a better diagnostic predictor of cardiovascular disease in Japanese diabetic patients than the existing definitions: additional analysis from the Japan Diabetes Complications Study.

Y. Yamasaki, Y. Ohashi, H. Sone, 2006, Diabetes care.

Association of cholesteryl ester transfer protein activity and TaqIB polymorphism with lipoprotein variations in Japanese subjects.

J. Sasaki, N. Yamada, H. Mabuchi, 2003, Metabolism: clinical and experimental.

Polymorphisms in four genes related to triglyceride and HDL-cholesterol levels in the general Japanese population in 2000.

Y. Ouchi, Y. Matsuzawa, T. Kita, 2005, Journal of atherosclerosis and thrombosis.

Comparison of Various Lipid Variables as Predictors of Coronary Heart Disease in Japanese Men and Women With Type 2 Diabetes

Y. Ohashi, H. Sone, Shiro Tanaka, 2012, Diabetes Care.

Effectiveness and Safety of Lipid-Lowering Drug Treatments in Japanese Patients with Familial Hypercholesterolemia: Familial Hypercholesterolemia Expert Forum (FAME) Study

S. Yamashita, H. Daida, H. Arai, 2021, Journal of atherosclerosis and thrombosis.

Metformin Attenuates Early-Stage Atherosclerosis in Mildly Hyperglycemic Oikawa-Nagao Mice

H. Sugihara, Y. Shuto, A. Asai, 2019, Journal of atherosclerosis and thrombosis.

Relationship between coronary artery disease and non-HDL-C, and effect of highly purified EPA on the risk of coronary artery disease in hypercholesterolemic patients treated with statins: sub-analysis of the Japan EPA Lipid Intervention Study (JELIS).

Y. Matsuzawa, K. Shimada, M. Matsuzaki, 2012, Journal of atherosclerosis and thrombosis.

Isohumulones modulate blood lipid status through the activation of PPAR alpha.

S. Mizutani, K. Kondo, S. Oikawa, 2005, Biochimica et biophysica acta.

Diagnosis and management of type I and type V hyperlipoproteinemia.

S. Yamashita, H. Sone, H. Arai, 2012, Journal of atherosclerosis and thrombosis.

[Lipoprotein glomerulopathy].

S. Oikawa, 2001, Nihon rinsho. Japanese journal of clinical medicine.

Liquid chromatography-tandem mass spectrometry determination of human plasma 1-palmitoyl-2-hydroperoxyoctadecadienoyl-phosphatidylcholine isomers via promotion of sodium adduct formation.

K. Nakagawa, A. Asai, Mototsugu Nagao, 2015, Analytical biochemistry.

Effects of daily aspirin on cancer incidence and mortality in the elderly Japanese

K. Shimada, N. Ishizuka, S. Uchiyama, 2018, Research and practice in thrombosis and haemostasis.

A trilogy of primary prevention statin trials. Panel discussion.

A. Gotto, Y. Matsuzawa, F. Sacks, 2007, Atherosclerosis. Supplements.

Serum lipid survey and its recent trend in the general Japanese population in 2000.

Y. Ouchi, Y. Matsuzawa, T. Kita, 2005, Journal of atherosclerosis and thrombosis.

Clinical effects of rosuvastatin, a new HMG-CoA reductase inhibitor, in Japanese patients with primary hypercholesterolemia: an early phase II study.

Y. Matsuzawa, J. Sasaki, K. Arakawa, 2002, Journal of atherosclerosis and thrombosis.

Guidelines for the management of familial hypercholesterolemia.

S. Yamashita, T. Okamura, H. Arai, 2012, Journal of atherosclerosis and thrombosis.

Association of glycated albumin with the presence of carotid plaque in patients with type 2 diabetes

H. Tamura, H. Sugihara, A. Asai, 2013, Journal of diabetes investigation.

Proposed guidelines for hypertriglyceridemia in Japan with non-HDL cholesterol as the second target.

S. Yamashita, K. Shimamoto, Y. Kiyohara, 2008, Journal of atherosclerosis and thrombosis.

Selectively Bred Diabetes Models: GK Rats, NSY Mice, and ON Mice.

L. Eliasson, A. Wendt, H. Sugihara, 2020, Methods in molecular biology.

Potential Protection Against Type 2 Diabetes in Obesity Through Lower CD36 Expression and Improved Exocytosis in β-Cells

L. Eliasson, C. Wollheim, A. Wendt, 2020, Diabetes.

Anti-angiogenic effect of TGFβ in aqueous humor

S. Oikawa, T. Toyota, Y. Ishigaki, 1998 .

Lipoprotein glomerulopathy: glomerular lipoprotein thrombi in a patient with hyperlipoproteinemia.

S. Oikawa, K. Yoshinaga, H. Sato, 1989, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Abnormal lipoprotein and apolipoprotein pattern in lipoprotein glomerulopathy.

S. Oikawa, T. Toyota, T. Saito, 1991, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Factors Associated with Carotid Atherosclerosis and Achilles Tendon Thickness in Japanese Patients with Familial Hypercholesterolemia: A Subanalysis of the Familial Hypercholesterolemia Expert Forum (FAME) Study

S. Yamashita, H. Daida, H. Arai, 2021, Journal of atherosclerosis and thrombosis.

Increase of serum phosphatidylcholine hydroperoxide dependent on glycemic control in type 2 diabetic patients.

S. Oikawa, T. Miyazawa, Y. Ishigaki, 2002, Diabetes research and clinical practice.

Genetic suppression of ghrelin receptors activates brown adipocyte function and decreases fat storage in rats

T. Nemoto, H. Sugihara, S. Oikawa, 2010, Regulatory Peptides.

Multicenter study to determine the diagnosis criteria of heterozygous familial hypercholesterolemia in Japan.

S. Yamashita, T. Okamura, H. Arai, 2012, Journal of atherosclerosis and thrombosis.

Interactions of Obesity and Glucose-stimulated Insulin Secretion in Familial Hypertriglyceridemia

S. Oikawa, F. Okuguchi, Y. Maruhama, 1978, Diabetes.

Relation of Serum Lipoprotein(a) Levels to Lipoprotein and Apolipoprotein Profiles and Atherosclerotic Diseases in Japanese Patients with Heterozygous Familial Hypercholesterolemia: Familial Hypercholesterolemia Expert Forum (FAME) Study

S. Yamashita, H. Daida, H. Arai, 2021, Journal of atherosclerosis and thrombosis.

Chylomicronemia caused by lipoprotein lipase gene mutation related to a hyper-response of insulin secretion to glucose.

T. Murano, J. Kamegai, H. Tamura, 2002, Internal medicine.

Polymorphisms of apolipoprotein e and methylenetetrahydrofolate reductase in the Japanese population.

Y. Ouchi, Y. Matsuzawa, T. Kita, 2007, Journal of atherosclerosis and thrombosis.

Prevalence of the metabolic syndrome in elderly and middle-aged Japanese

Y. Ouchi, Y. Matsuzawa, T. Kita, 2010 .

Liver Transplantation for Homozygous Familial Hypercholesterolemia

H. Katagiri, S. Oikawa, S. Satomi, 2019, Journal of atherosclerosis and thrombosis.

The effects of partial use of formula diet on weight reduction and metabolic variables in obese type 2 diabetic patients--multicenter trial.

N. Sakane, N. Yamada, S. Ishibashi, 2013, Obesity research & clinical practice.

Hypothalamic growth hormone secretagogue receptor regulates growth hormone secretion, feeding, and adiposity.

J. Kamegai, H. Tamura, H. Sugihara, 2002, The Journal of clinical investigation.

Association of single-nucleotide polymorphisms in MTMR9 gene with obesity.

Yusuke Nakamura, A. Sekine, T. Tsunoda, 2007, Human molecular genetics.

Relationships between plasma fatty acid composition and coronary artery disease.

Y. Matsuzawa, K. Shimada, M. Matsuzaki, 2011, Journal of atherosclerosis and thrombosis.

Screening of 336 single-nucleotide polymorphisms in 85 obesity-related genes revealed McKusick–Kaufman syndrome gene variants are associated with metabolic syndrome

Yusuke Nakamura, K. Nakao, T. Funahashi, 2009, Journal of Human Genetics.

Effect of mulberry leaf extract with enriched 1‐deoxynojirimycin content on postprandial glycemic control in subjects with impaired glucose metabolism

Y. Kojima, K. Nakagawa, Toshiyuki Kimura, 2011, Journal of diabetes investigation.

Determination of lipid hydroperoxides in low density lipoprotein from human plasma using high performance liquid chromatography with chemiluminescence detection.

S. Oikawa, K. Fujimoto, T. Miyazawa, 1990, Biomedical chromatography : BMC.

Oxidized but not acetylated low-density lipoprotein reduces preproinsulin mRNA expression and secretion of insulin from HIT-T15 cells.

K. Nakagawa, H. Sugihara, S. Oikawa, 2005, Biochimica et biophysica acta.

Triiodothyronine (T3) stimulates food intake via enhanced hypothalamic AMP-activated kinase activity

J. Kamegai, H. Tamura, S. Ishii, 2008, Regulatory Peptides.

Effect of HMG-CoA reductase inhibitor on plasma cholesteryl ester transfer protein activity in primary hypercholesterolemia: comparison among CETP/TaqIB genotype subgroups.

S. Oikawa, Y. Ishigaki, H. Kotake, 2002, Journal of atherosclerosis and thrombosis.

Ion-trap tandem mass spectrometric analysis of Amadori-glycated phosphatidylethanolamine in human plasma with or without diabetes Published, JLR Papers in Press, September 8, 2005. DOI 10.1194/jlr.D500025-JLR200

H. Otani, K. Nakagawa, S. Oikawa, 2005, Journal of Lipid Research.

Fructose ingestion enhances atherosclerosis and deposition of advanced glycated end-products in cholesterol-fed rabbits.

S. Oikawa, T. Miyazawa, T. Toyota, 2005, Journal of atherosclerosis and thrombosis.

Antiangiogenic and anticancer potential of unsaturated vitamin E (tocotrienol).

K. Nakagawa, A. Asai, S. Oikawa, 2009, The Journal of nutritional biochemistry.

Abnormal response of pancreatic glucagon to glycemic changes in diabetes mellitus.

S. Oikawa, K. Watanabe, A. Ohneda, 1978, The Journal of clinical endocrinology and metabolism.

T lymphocytes increase the synthesis of esterified cholesterol in human monocyte-derived macrophages by activation of the scavenger pathway.

S. Oikawa, T. Toyota, K. Hayasaka, 1992, Biochimica et biophysica acta.

Effect of low density lipoprotein on DNA synthesis of cultured human arterial smooth muscle cells.

S. Oikawa, Y. Goto, S. Hori, 1987, Atherosclerosis.

Evidence for direct effect of growth hormone on capillary basement membrane thickness.

S. Oikawa, Y. Maruhama, Y. Goto, 1985, The Tohoku journal of experimental medicine.

Effect of Medium Glucose Concentration on Glucose Uptake by Rat Arterial Smooth Muscle Cells and Subcutaneous Fibroblasts in Culture

S. Oikawa, Y. Maruhama, 1980 .

Responsiveness to insulin of glucose metabolism in cultured rat and human arterial smooth muscle cells.

S. Oikawa, F. Okuguchi, Y. Maruhama, 1979, The Tohoku journal of experimental medicine.

Biliary lipid composition in heterozygous familial hypercholesterolemia and influence of treatment with probucol

S. Oikawa, T. Toyota, M. Koizumi, 1994, Digestive Diseases and Sciences.

Effect of taurine administration on serum lipid and biliary lipid composition in man.

S. Oikawa, T. Toyota, M. Koizumi, 1989, The Tohoku journal of experimental medicine.

ApoE-2/E-3 ratio of very low density lipoprotein in diabetes mellitus.

S. Oikawa, T. Toyota, R. Abe, 1985, The Tohoku journal of experimental medicine.

Generation of polyclonal antiserum against the growth hormone secretagogue receptor (GHS-R): evidence that the GHS-R exists in the hypothalamus, pituitary and stomach of rats.

J. Kamegai, H. Sugihara, I. Wakabayashi, 2001, Life sciences.

Prevention of diet-induced obesity by dietary isomerized hop extract containing isohumulones, in rodents

O. Ezaki, S. Oikawa, N. Tsuboyama-Kasaoka, 2005, International Journal of Obesity.

Erratum to “Effects of EPA on coronary artery disease in hypercholesterolemic patients with multiple risk factors: Sub-analysis of primary prevention cases from the Japan EPA Lipid Intervention Study (JELIS)” [Atherosclerosis 200 (2008) 135–140]

Y. Matsuzawa, K. Shimada, M. Matsuzaki, 2009 .

Insulin-like growth factor-I down-regulates ghrelin receptor (growth hormone secretagogue receptor) expression in the rat pituitary

J. Kamegai, H. Tamura, S. Ishii, 2005, Regulatory Peptides.

The effect of agouti-related protein on growth hormone secretion in adult male rats

J. Kamegai, H. Tamura, S. Ishii, 2005, Regulatory Peptides.

Ghrelin stimulates GH but not food intake in arcuate nucleus ablated rats.

J. Kamegai, H. Tamura, S. Ishii, 2002, Endocrinology.

Effects of insulin, leptin, and glucagon on ghrelin secretion from isolated perfused rat stomach

J. Kamegai, H. Tamura, S. Ishii, 2004, Regulatory Peptides.

Microalbuminuria is closely related to diabetic macroangiopathy.

S. Oikawa, T. Toyota, A. Sasaki, 1999, Diabetes research and clinical practice.

Familial hypercholesterolemia.

S. Kihara, S. Yamashita, T. Hiro, 2014, Journal of atherosclerosis and thrombosis.

Severe Insulin-resistant Diabetes due to Insulin Antibodies Associated with Eosinophilia.

H. Sugihara, Mototsugu Nagao, S. Oikawa, 2015, Internal medicine.

Virus-mediated Transduction of Apolipoprotein E (ApoE)-Sendai Develops Lipoprotein Glomerulopathy in ApoE-deficient Mice*

Takashi Suzuki, H. Sasano, J. Sasaki, 2000, The Journal of Biological Chemistry.

A non-acromegalic case of multiple endocrine neoplasia type 1 accompanied by a growth hormone-releasing hormone-producing pancreatic tumor

T. Tajiri, Z. Naito, J. Kamegai, 2007, Journal of endocrinological investigation.

Frequency of Achilles Tendon Xanthoma in Patients with Acute Coronary Syndrome

H. Sugihara, Mototsugu Nagao, S. Oikawa, 2017, Journal of atherosclerosis and thrombosis.

Role of ghrelin in streptozotocin-induced diabetic hyperphagia.

J. Kamegai, H. Tamura, S. Ishii, 2002, Endocrinology.

Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis

Y. Matsuzawa, K. Shimada, M. Matsuzaki, 2007, The Lancet.

Long-term outcome after living donor liver transplantation for two cases of homozygous familial hypercholesterolemia from a heterozygous donor.

S. Oikawa, Y. Akamatsu, S. Satomi, 2007, Journal of atherosclerosis and thrombosis.

The recovery of dysfunctional lipoprotein lipase (Asp204-Glu) activity by modification of substrate.

T. Murano, K. Shirai, S. Oikawa, 2005, Atherosclerosis.

[Hyperlipidemia in life style disease].

S. Oikawa, 2001, Journal of Nippon Medical School = Nippon Ika Daigaku zasshi.

The effect of serum on low density lipoprotein metabolism of human monocyte-derived macrophages.

S. Oikawa, T. Toyota, K. Hayasaka, 1993, The Tohoku journal of experimental medicine.

Oxidative Modification of Phosphatidylcholine in Atherosclerotic Vascular Disease

A. Asai, S. Oikawa, 2011 .

Apolipoprotein E phenotypes of normo- and hyperlipoproteinemia in Japanese.

S. Oikawa, T. Toyota, Y. Goto, 1988, The Tohoku journal of experimental medicine.

Effects of Mulberry Leaf Extract Rich in 1-Deoxynojirimycin on Blood Lipid Profiles in Humans

Y. Kojima, K. Nakagawa, Toshiyuki Kimura, 2010, Journal of clinical biochemistry and nutrition.

Food-grade mulberry powder enriched with 1-deoxynojirimycin suppresses the elevation of postprandial blood glucose in humans.

Y. Kojima, K. Nakagawa, H. Kubota, 2007, Journal of agricultural and food chemistry.

Lipoprotein glomerulopathy. Report of a normolipidemic case and review of the literature.

S. Oikawa, K. Yoshinaga, K. Abe, 1993, American journal of nephrology.

Report of the Japan Atherosclerosis Society (JAS) Guideline for Diagnosis and Treatment of Hyperlipidemia in Japanese adults.

S. Yamashita, J. Sasaki, N. Yamada, 2002, Journal of atherosclerosis and thrombosis.

Identical germline mutations in the TMEM127 gene in two unrelated Japanese patients with bilateral pheochromocytoma

H. Shimano, Tsuyoshi Watanabe, Yuria Saito, 2012, Clinical endocrinology.

In vivo angiogenesis is suppressed by unsaturated vitamin E, tocotrienol.

K. Nakagawa, S. Oikawa, T. Miyazawa, 2007, The Journal of nutrition.

Effects of EPA on coronary artery disease in hypercholesterolemic patients with multiple risk factors: sub-analysis of primary prevention cases from the Japan EPA Lipid Intervention Study (JELIS).

Y. Matsuzawa, K. Shimada, M. Matsuzaki, 2008, Atherosclerosis.

LC-MS/MS analysis of carboxymethylated and carboxyethylated phosphatidylethanolamines in human erythrocytes and blood plasma[S]

K. Nakagawa, A. Asai, S. Oikawa, 2010, Journal of Lipid Research.

Aminophospholipid glycation and its inhibitor screening system: a new role of pyridoxal 5′-phosphate as the inhibitor Published, JLR Papers in Press, February 9, 2006.

K. Nakagawa, S. Oikawa, T. Miyazawa, 2006, Journal of Lipid Research.

Animal Models of Diabetes: Methods and Protocols

L. Eliasson, A. Wendt, H. Sugihara, 2020 .

Comparison of three α‐glucosidase inhibitors for glycemic control and bodyweight reduction in Japanese patients with obese type 2 diabetes

M. Kawakami, H. Tamura, H. Sugihara, 2013, Journal of diabetes investigation.

Ion-trap tandem mass spectrometric analysis of squalene monohydroperoxide isomers in sunlight-exposed human skin Published, JLR Papers in Press, September 11, 2007.

K. Nakagawa, S. Oikawa, T. Miyazawa, 2007, Journal of Lipid Research.

Occurrence of orally administered mulberry 1-deoxynojirimycin in rat plasma.

K. Nakagawa, H. Kubota, Toshiyuki Kimura, 2007, Journal of agricultural and food chemistry.

Validation of an Ion Trap Tandem Mass Spectrometric Analysis of Mulberry 1-Deoxynojirimycin in Human Plasma: Application to Pharmacokinetic Studies

K. Nakagawa, H. Kubota, Toshiyuki Kimura, 2008, Bioscience, biotechnology, and biochemistry.

Analysis of the factors associated with Tc-99m pertechnetate uptake in thyrotoxicosis and graves' disease.

S. Oikawa, N. Emoto, Keiichi Cho, 2006, Journal of Nippon Medical School = Nippon Ika Daigaku zasshi.

Analysis of the Factors Associated with Tc-99 m Pertechnetate Uptake in Thyrotoxicosis and Graves ’ Disease

S. Oikawa, N. Emoto, Keiichi Cho, 2006 .

3. Obesity and Dyslipidemia.

S. Oikawa, 2011 .

Isohumulones, Bitter Acids Derived from Hops, Activate Both Peroxisome Proliferator-activated Receptor α and γ and Reduce Insulin Resistance*

O. Ezaki, S. Oikawa, N. Tsuboyama-Kasaoka, 2004, Journal of Biological Chemistry.

delta-Tocotrienol suppresses VEGF induced angiogenesis whereas alpha-tocopherol does not.

K. Nakagawa, S. Oikawa, T. Miyazawa, 2009, Journal of agricultural and food chemistry.

Lipoprotein Glomerulopathy: Renal Lipidosis Induced by Novel Apolipoprotein E Variants

J. Sasaki, S. Oikawa, Hiroshi Sato, 1999, Nephron.

Lipoprotein glomerulopathy: A new aspect of lipid induced glomerular injury

S. Oikawa, Hiroshi Sato, T. Saito, 1995 .

Tumor anti-angiogenic effect and mechanism of action of delta-tocotrienol.

K. Nakagawa, S. Oikawa, T. Miyazawa, 2008, Biochemical pharmacology.

The role of pituitary ghrelin in growth hormone (GH) secretion: GH-releasing hormone-dependent regulation of pituitary ghrelin gene expression and peptide content.

R. Kineman, J. Kamegai, H. Tamura, 2004, Endocrinology.

Isohumulones modulate blood lipid status through the activation of PPARa

S. Mizutani, K. Kondo, S. Oikawa, 2005 .

INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese

Yusuke Nakamura, K. Nakao, T. Funahashi, 2008, Journal of Human Genetics.

Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population

Yusuke Nakamura, K. Nakao, T. Funahashi, 2009, Journal of Human Genetics.

Gender difference in coronary events in relation to risk factors in Japanese hypercholesterolemic patients treated with low-dose simvastatin.

Y. Matsuzawa, K. Shimamoto, M. Matsuzaki, 2006, Circulation journal : official journal of the Japanese Circulation Society.

Postprandial Increase in Energy Expenditure Correlates with Body Weight Reduction in Patients with Type 2 Diabetes Receiving Diet Therapy

H. Sugihara, A. Asai, Mototsugu Nagao, 2017, Journal of atherosclerosis and thrombosis.

CDH13 Polymorphisms are Associated with Adiponectin Levels and Metabolic Syndrome Traits Independently of Visceral Fat Mass.

T. Kitamoto, T. Funahashi, Y. Matsuzawa, 2016, Journal of atherosclerosis and thrombosis.

ADIPOQ polymorphisms are associated with insulin resistance in Japanese women.

T. Kitamoto, T. Funahashi, Y. Matsuzawa, 2015, Endocrine journal.

Different pathogenesis of glucose intolerance in two subtypes of primary aldosteronism: Aldosterone‐producing adenoma and idiopathic hyperaldosteronism

H. Sugihara, Mototsugu Nagao, S. Oikawa, 2020, Journal of diabetes investigation.

Serum level of triglycerides is a potent risk factor comparable to LDL cholesterol for coronary heart disease in Japanese patients with type 2 diabetes: subanalysis of the Japan Diabetes Complications Study (JDCS).

Y. Yamasaki, Y. Ohashi, H. Sone, 2011, The Journal of clinical endocrinology and metabolism.

Telomere shortening of peripheral blood mononuclear cells in coronary disease patients with metabolic disorders.

T. Shimosegawa, S. Oikawa, Y. Kinouchi, 2003, Internal medicine.

Selective breeding of mice for different susceptibilities to high fat diet‐induced glucose intolerance: Development of two novel mouse lines, Selectively bred Diet‐induced Glucose intolerance‐Prone and ‐Resistant

H. Sugihara, A. Asai, Mototsugu Nagao, 2011, Journal of diabetes investigation.

Large scale cohort study of the relationship between serum cholesterol concentration and coronary events with low-dose simvastatin therapy in Japanese patients with hypercholesterolemia.

Y. Matsuzawa, K. Shimamoto, M. Matsuzaki, 2002, Circulation journal : official journal of the Japanese Circulation Society.

Fat intake and the development of type 2 diabetes.

H. Sugihara, A. Asai, Mototsugu Nagao, 2015, Endocrine journal.

Variations in the FTO gene are associated with severe obesity in the Japanese

Yusuke Nakamura, K. Nakao, T. Funahashi, 2008, Journal of Human Genetics.

Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity.

Yusuke Nakamura, A. Sekine, T. Tsunoda, 2007, The Journal of clinical endocrinology and metabolism.

Investigation of Obstructive Sleep Apnea Using Portable Monitors and Health Check Data in Japanese Drivers

H. Kokuto, H. Sugihara, S. Oikawa, 2018, Journal of atherosclerosis and thrombosis.

Comparison of pituitary–adrenal responsiveness between insulin tolerance test and growth hormone-releasing peptide-2 test: A pilot study

H. Tamura, S. Ishii, H. Sugihara, 2010, Peptides.

Growth hormone-releasing hormone (GHRH) neurons in the arcuate nucleus (Arc) of the hypothalamus are decreased in transgenic rats whose expression of ghrelin receptor is attenuated: Evidence that ghrelin receptor is involved in the up-regulation of GHRH expression in the arc.

T. Nemoto, H. Sugihara, S. Oikawa, 2006, Endocrinology.

Fasting plasma glucose level-based formula for estimating starting daily dose in basal-bolus insulin therapy

H. Sugihara, Mototsugu Nagao, S. Oikawa, 2023, Scientific Reports.

Multiple daily insulin injections ameliorate QT interval by lowering blood glucose levels in patients with type 2 diabetes

H. Sugihara, Mototsugu Nagao, S. Oikawa, 2021, Therapeutic advances in endocrinology and metabolism.

Severity and multiplicity of microvascular complications are associated with QT interval prolongation in patients with type 2 diabetes

H. Sugihara, A. Asai, Mototsugu Nagao, 2017, Journal of diabetes investigation.

Suppressive effect of EPA on the incidence of coronary events in hypercholesterolemia with impaired glucose metabolism: Sub-analysis of the Japan EPA Lipid Intervention Study (JELIS).

Y. Matsuzawa, K. Shimada, M. Matsuzaki, 2009, Atherosclerosis.

Hypothalamic Neuropeptide Y/Y1 Receptor Pathway Activated by a Reduction in Circulating Leptin, but Not by an Increase in Circulating Ghrelin, Contributes to Hyperphagia Associated with Triiodothyronine-Induced Thyrotoxicosis

J. Kamegai, H. Tamura, S. Ishii, 2003, Neuroendocrinology.

Leptin production capacity determines food intake and susceptibility to obesity-induced diabetes in Oikawa–Nagao Diabetes-Prone and Diabetes-Resistant mice

H. Sugihara, A. Asai, Mototsugu Nagao, 2020, Diabetologia.

Reduction in the Recurrence of Stroke by Eicosapentaenoic Acid for Hypercholesterolemic Patients: Subanalysis of the JELIS Trial

Kortaro Tanaka, Y. Matsuzawa, K. Shimada, 2008, Stroke.

Association of variations in the FTO, SCG3 and MTMR9 genes with metabolic syndrome in a Japanese population

T. Kitamoto, A. Sekine, K. Nakao, 2011, Journal of Human Genetics.

Association of serum apolipoprotein B48 level with the presence of carotid plaque in type 2 diabetes mellitus.

S. Yamashita, H. Tamura, S. Ishii, 2008, Diabetes research and clinical practice.

Effect of Cilostazol on Lipid, Uric Acid and Glucose Metabolism in Patients with Impaired Glucose Tolerance or Type 2 Diabetes Mellitus

S. Hisamichi, A. Fukao, S. Oikawa, 2001 .

Trial Reduction in the Recurrence of Stroke by Eicosapentaenoic Acid for Hypercholesterolemic

Itakura, Kortaro Tanaka, Y. Matsuzawa, 2008 .

Effect of impaired glucose tolerance on atherosclerotic lesion formation: an evaluation in selectively bred mice with different susceptibilities to glucose intolerance.

H. Sugihara, Y. Shuto, A. Asai, 2013, Atherosclerosis.

Incremental effects of eicosapentaenoic acid on cardiovascular events in statin-treated patients with coronary artery disease.

Y. Matsuzawa, K. Shimada, M. Matsuzaki, 2009, Circulation journal : official journal of the Japanese Circulation Society.

The Risk of Cardiovascular Events in Japanese Hypertensive Patients with Hypercholesterolemia: Sub-Analysis of the Japan Lipid Intervention Trial (J-LIT) Study, a Large-Scale Observational Cohort Study

Y. Matsuzawa, K. Shimamoto, M. Matsuzaki, 2005, Hypertension Research.

Large-scale cohort study on the relationship between serum lipid concentrations and risk of cerebrovascular disease under low-dose simvastatin in Japanese patients with hypercholesterolemia: sub-analysis of the Japan Lipid Intervention Trial (J-LIT).

Y. Matsuzawa, K. Shimamoto, M. Matsuzaki, 2005, Circulation journal : official journal of the Japanese Circulation Society.

Obesity as a risk factor for coronary events in Japanese patients with hypercholesterolemia on low-dose simvastatin therapy.

Y. Matsuzawa, K. Shimamoto, M. Matsuzaki, 2010, Journal of atherosclerosis and thrombosis.

Prevalence of metabolic syndrome in the general Japanese population in 2000.

Y. Ouchi, Y. Matsuzawa, T. Kita, 2006, Journal of atherosclerosis and thrombosis.

Steps to preventingType 2 diabetes: exercise, walk more, or sit less?

U. Das, S. Oikawa, Catherine Chan, 2012 .

High purity tocotrienols attenuate atherosclerotic lesion formation in apoE-KO mice.

K. Nakagawa, A. Asai, S. Oikawa, 2017, The Journal of nutritional biochemistry.

Reduced sulfation of chondroitin sulfate in thyroglobulin derived from human papillary thyroid carcinomas

S. Oikawa, N. Emoto, H. Toyoda, 2007, Cancer Science.

Predictive Value of the Cardio‐Ankle Vascular Index for Cardiovascular Events in Patients at Cardiovascular Risk

J. Higaki, K. Kotani, H. Yagi, 2021, Journal of the American Heart Association.

Aspirin for Stroke Prevention in Elderly Patients With Vascular Risk Factors: Japanese Primary Prevention Project

K. Shimada, N. Ishizuka, S. Uchiyama, 2016, Stroke.

Long-term lifestyle intervention lowers the incidence of stroke in Japanese patients with type 2 diabetes: a nationwide multicentre randomised controlled trial (the Japan Diabetes Complications Study)

H. Yamashita, Y. Yamasaki, Y. Ohashi, 2010, Diabetologia.

Background to discuss guidelines for control of plasma HDL-cholesterol in Japan.

S. Yamashita, H. Sone, H. Arai, 2012, Journal of atherosclerosis and thrombosis.

[Internal medicine and neurological diseases: progress in diagnosis and treatment. Topics: II neurological diseases related to diabetes mellitus; 2. Cerebral infarction, coma, hypoglycemia].

Mototsugu Nagao, S. Oikawa, Kyoko Inagaki, 2012, Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine.

Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.

K. Shimada, N. Ishizuka, S. Uchiyama, 2014, JAMA.

Components of metabolic syndrome and their combinations as predictors of cardiovascular disease in Japanese patients with type 2 diabetes. Implications for improved definition. Analysis from Japan Diabetes Complications Study (JDCS).

Y. Yamasaki, Y. Ohashi, H. Sone, 2009, Journal of atherosclerosis and thrombosis.

Ezetimibe Lipid-Lowering Trial on Prevention of Atherosclerotic Cardiovascular Disease in 75 or Older (EWTOPIA 75): A Randomized Controlled Trial.

Y. Ouchi, S. Yamashita, Y. Ohashi, 2019, Circulation.

Involvement of Rac GTPase activation in phosphatidylcholine hydroperoxide-induced THP-1 cell adhesion to ICAM-1.

K. Nakagawa, A. Asai, Mototsugu Nagao, 2011, Biochemical and biophysical research communications.

Inhibitory effects of amlodipine and fluvastatin on the deposition of advanced glycation end products in aortic wall of cholesterol and fructose-fed rabbits.

S. Oikawa, T. Hashimoto, K. Akira, 2006, Biological & pharmaceutical bulletin.

Low-Dose Aspirin for Primary Prevention of Cardiovascular Events in Elderly Japanese Patients with Atherosclerotic Risk Factors: Subanalysis of a Randomized Clinical Trial (JPPP-70)

K. Shimada, N. Ishizuka, S. Uchiyama, 2018, American Journal of Cardiovascular Drugs.

Low-Dose Aspirin for Primary Prevention of Cardiovascular Events in Japanese Patients 60 Years or OlderWith Atherosclerotic Risk Factors A Randomized Clinical Trial

K. Shimada, N. Ishizuka, S. Uchiyama, 2014 .

Practical dietary calorie management, body weight control and energy expenditure of diabetic patients in short-term hospitalization.

K. Tsuda, H. Tamura, H. Sugihara, 2010, Journal of atherosclerosis and thrombosis.

Replication study of 15 recently published Loci for body fat distribution in the Japanese population.

T. Kitamoto, A. Sekine, K. Nakao, 2013, Journal of atherosclerosis and thrombosis.

NUDT3 rs206936 is associated with body mass index in obese Japanese women.

T. Kitamoto, A. Sekine, K. Nakao, 2013, Endocrine journal.

Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography

T. Kitamoto, A. Sekine, K. Nakao, 2012, Journal of Human Genetics.

Genetic variations in the CYP17A1 and NT5C2 genes are associated with a reduction in visceral and subcutaneous fat areas in Japanese women

T. Kitamoto, A. Sekine, K. Nakao, 2011, Journal of Human Genetics.

Computed tomography analysis of the association between the SH2B1 rs7498665 single-nucleotide polymorphism and visceral fat area

T. Kitamoto, A. Sekine, K. Nakao, 2011, Journal of Human Genetics.

Polymorphisms in NRXN3, TFAP2B, MSRA, LYPLAL1, FTO and MC4R and their effect on visceral fat area in the Japanese population

Yusuke Nakamura, K. Nakao, T. Funahashi, 2010, Journal of Human Genetics.

Role of apolipoprotein E variants in lipoprotein glomerulopathy and other renal lipidoses

S. Oikawa, T. Yamamoto, Y. Ishigaki, 2001, Clinical and Experimental Nephrology.

Etiological significance of apolipoprotein E mutations in lipoprotein glomerulopathy.

Tokuo T. Yamamoto, S. Oikawa, Y. Ishigaki, 2002, Trends in cardiovascular medicine.

Lipoprotein glomerulopathy: significance of lipoprotein and ultrastructural features.

J. Sasaki, S. Oikawa, T. Sato, 1999, Kidney international. Supplement.

Lipoprotein glomerulopathy and its pathogenesis.

S. Oikawa, H. Sato, T. Saito, 1997, Contributions to nephrology.

Appearance of multidisperse low density lipoprotein and altered lipoprotein composition in non-insulin-dependent diabetes with type IIa hyperlipoproteinemia.

S. Oikawa, H. Kotake, Y. Goto, 1989, Metabolism: clinical and experimental.

Regulation of the ghrelin gene: growth hormone-releasing hormone upregulates ghrelin mRNA in the pituitary.

J. Kamegai, H. Tamura, T. Shimizu, 2001, Endocrinology.

Efficacy and Safety of Long-term Coadministration of Fenofibrate and Ezetimibe in Patients with Combined Hyperlipidemia: Results of the EFECTL Study

S. Yamashita, J. Sasaki, S. Kono, 2017, Journal of atherosclerosis and thrombosis.

Effects of Beraprost Sodium (Dorner®) in Patients with Diabetes Mellitus Complicated by Chronic Arterial Obstruction

S. Oikawa, T. Toyota, 2002, Angiology.

Efficacy and safety of sitagliptin treatment in older adults with moderately controlled type 2 diabetes: the STREAM study

J. Sasaki, H. Sugihara, Mototsugu Nagao, 2023, Scientific Reports.

Isohumulones, bitter acids derived from hops, activate both peroxisome proliferator-activated receptor alpha and gamma and reduce insulin resistance.

O. Ezaki, S. Oikawa, N. Tsuboyama-Kasaoka, 2004, The Journal of biological chemistry.

Analysis of Lipoproteins and Apolipoproteins in Normocholesterolemic and Hypercholesterolemic Dysbetalipoproteinemia: -3 Cases with the E 2/2 Homozygous Phenotype-

S. Oikawa, T. Toyota, Y. Gotō, 1985 .

Rationale, design, and baseline data of the Japanese Primary Prevention Project (JPPP)-a randomized, open-label, controlled trial of aspirin versus no aspirin in patients with multiple risk factors for vascular events.

K. Shimada, N. Ishizuka, N. Yamada, 2010, American heart journal.

Influence of blood pressure on the effects of low-dose asprin in elderly patients with multiple atherosclerotic risks

K. Shimada, N. Ishizuka, S. Uchiyama, 2019, Journal of hypertension.

Effects of Hypertension and Type 2 Diabetes Mellitus on the Risk of Total Cardiovascular Events in Japanese Patients with Hypercholesterolemia: Implications from the Japan Lipid Intervention Trial (J-LIT)

Y. Matsuzawa, K. Shimamoto, M. Matsuzaki, 2007, Hypertension Research.

[A case of islet cell tumor].

S. Oikawa, N. Chida, H. Onodera, 1985, Rinsho hoshasen. Clinical radiography.

Human Arterial Smooth Muscle Cell Proliferation in Diabetes

A. Kikuchi, S. Oikawa, K. Hayasaka, 1996, Diabetes.

Hypothalamic growth hormone secretagogue receptor regulates growth hormone secretion, feeding, and adiposity

J. Kamegai, H. Tamura, H. Sugihara, 2002 .

CDH13 Polymorphisms are Associated with Adiponectin Levels and Metabolic Syndrome Traits Independently of Visceral Fat Mass.

T. Kitamoto, T. Funahashi, Y. Matsuzawa, 2016, Journal of atherosclerosis and thrombosis.

Suppressive effect of EPA on the incidence of coronary events in hypercholesterolemia with impaired glucose metabolism: Sub-analysis of the Japan EPA Lipid Intervention Study (JELIS).

Y. Matsuzawa, K. Shimada, M. Matsuzaki, 2009, Atherosclerosis.

Inhibitory effect of pancreatic elastase on thickening of the renal glomerular basement membrane in the spontaneously diabetic rat.

S. Oikawa, Y. Gotō, M. Kakizaki, 1982, The Tohoku journal of experimental medicine.

COVID-19 Early Detection Tool for Elder Abuse during Epidemics, Digital Analysis of Color Tone on the Surface of the Skin in Elderly People

S. Oikawa, H. Hyodoh, N. Yamada, 2021 .

Waist Circumference as a Cardiovascular and Metabolic Risk in Japanese Patients With Type 2 Diabetes

Y. Yamasaki, Y. Ohashi, H. Sone, 2009, Obesity.

The estrogen receptor (ER) α, but not ER β, gene is expressed in hypothalamic growth hormone-releasing hormone neurons of the adult female rat

J. Kamegai, H. Tamura, S. Ishii, 2005, Neuroscience Research.

DIABETES AND ATHEROSCLEROSIS

S. Oikawa, T. Toyota, H. Kotake, 2000 .