Ben Farmer

发表

Insulin Delivery Into the Peripheral Circulation: A Key Contributor to Hypoglycemia in Type 1 Diabetes

D. Edgerton, E. Donahue, A. Cherrington, 2015, Diabetes.

Chronic overeating impairs hepatic glucose uptake and disposition.

A. Cherrington, G. Kraft, D. Neal, 2015, American journal of physiology. Endocrinology and metabolism.

Chronic hepatic artery ligation does not prevent liver from differentiating portal vs. peripheral glucose delivery.

A. Cherrington, D. Neal, Ben Farmer, 2003, American journal of physiology. Endocrinology and metabolism.

Hepatic glucose uptake and disposition during short-term high-fat vs. high-fructose feeding.

P. Roach, A. Cherrington, G. Kraft, 2014, American journal of physiology. Endocrinology and metabolism.

Targeting insulin to the liver corrects defects in glucose metabolism caused by peripheral insulin delivery.

D. Edgerton, A. Cherrington, Phillip E. Williams, 2019, JCI insight.

C-peptide enhances glucagon secretion in response to hyperinsulinemia under euglycemic and hypoglycemic conditions

A. Cherrington, S. Warner, Ben Farmer, 2021, JCI insight.

Superior Glycemic Control With a Glucose-Responsive Insulin Analog: Hepatic and Nonhepatic Impacts

C. Moyes, D. Kelley, A. Cherrington, 2018, Diabetes.

Portal infusion of escitalopram enhances hepatic glucose disposal in conscious dogs.

A. Cherrington, D. Neal, Ben Farmer, 2009, European journal of pharmacology.

Effects of hyperglycemia on hepatic gluconeogenic flux during glycogen phosphorylase inhibition in the conscious dog.

D. Edgerton, A. Cherrington, D. Neal, 2004, American journal of physiology. Endocrinology and metabolism.

Peripherally delivered hepatopreferential insulin analog insulin‐406 mimics the hypoglycaemia‐sparing effect of portal vein human insulin infusion in dogs

A. Cherrington, Susanne Hostrup, J. Gregory, 2019, Diabetes, obesity & metabolism.

Effects of hyperglycemia, glucagon, and epinephrine on renal glucose release in the conscious dog.

P. Flakoll, E. Donahue, C. Chu, 2004, Metabolism: clinical and experimental.

Molecular Characterization of Insulin-Mediated Suppression of Hepatic Glucose Production In Vivo

P. Roach, D. Edgerton, E. Donahue, 2010, Diabetes.

Impact of continuous and pulsatile insulin delivery on net hepatic glucose uptake.

O. McGuinness, A. Cherrington, Ben Farmer, 2005, American journal of physiology. Endocrinology and metabolism.

Insulin-induced hypoglycemia increases hepatic sensitivity to glucagon in dogs.

P. Roach, A. Cherrington, Ben Farmer, 2010, The Journal of clinical investigation.

Interaction of glucagon and epinephrine in the control of hepatic glucose production in the conscious dog.

P. Flakoll, E. Donahue, C. Chu, 2003, American journal of physiology. Endocrinology and metabolism.

MetAP2 Inhibitor Treatment of High-Fat and -Fructose Fed Dogs: Impact on the Response to Oral Glucose Ingestion and a Hyperinsulinemic Hyperglycemic Clamp.

T. Hughes, A. Cherrington, G. Kraft, 2020, American journal of physiology. Endocrinology and metabolism.

Effects of insulin deficiency or excess on hepatic gluconeogenic flux during glycogenolytic inhibition in the conscious dog.

D. Edgerton, A. Cherrington, D. Neal, 2002, Diabetes.

Changes in Glucose and Fat Metabolism in Response to the Administration of a Hepato-Preferential Insulin Analog

D. Edgerton, A. Cherrington, M. Scott, 2014, Diabetes.

Intraportally delivered GLP-1, in the presence of hyperglycemia induced via peripheral glucose infusion, does not change whole body glucose utilization.

D. Edgerton, A. Cherrington, M. Scott, 2008, American journal of physiology. Endocrinology and metabolism.

Insulin secretion-independent effects of GLP-1 on canine liver glucose metabolism do not involve portal vein GLP-1 receptors.

D. Dardevet, A. Cherrington, D. Neal, 2005, American journal of physiology. Gastrointestinal and liver physiology.

Insulin's direct hepatic effect explains the inhibition of glucose production caused by insulin secretion.

R. Printz, R. O’Brien, D. Edgerton, 2017, JCI insight.

Portal glucose delivery stimulates muscle but not liver protein metabolism.

D. Dardevet, E. Donahue, A. Cherrington, 2012, American journal of physiology. Endocrinology and metabolism.

Chronic consumption of a high-fat/high-fructose diet renders the liver incapable of net hepatic glucose uptake.

A. Cherrington, M. Scott, D. Neal, 2010, American journal of physiology. Endocrinology and metabolism.

Brain insulin action augments hepatic glycogen synthesis without suppressing glucose production or gluconeogenesis in dogs.

A. Mari, V. Saraswathi, D. Edgerton, 2011, The Journal of clinical investigation.

Portal Vein Glucose Entry Triggers a Coordinated Cellular Response That Potentiates Hepatic Glucose Uptake and Storage in Normal but Not High-Fat/High-Fructose–Fed Dogs

P. Roach, A. Cherrington, G. Kraft, 2013, Diabetes.

Vagal cooling and concomitant portal norepinephrine infusion do not reduce net hepatic glucose uptake in conscious dogs.

D. Edgerton, A. Cherrington, M. Pagliassotti, 2004, American journal of physiology. Regulatory, integrative and comparative physiology.

Effect of portal glucose sensing on incretin hormone secretion in a canine model.

D. Edgerton, A. Cherrington, M. Nauck, 2019, American journal of physiology. Endocrinology and metabolism.

Morning Hyperinsulinemia Primes the Liver for Glucose Uptake and Glycogen Storage Later in the Day

A. Cherrington, Phillip E. Williams, G. Kraft, 2018, Diabetes.

A Cyclic Guanosine Monophosphate–Dependent Pathway Can Regulate Net Hepatic Glucose Uptake in Vivo

P. Roach, A. Cherrington, Ben Farmer, 2012, Diabetes.

Direct and indirect effects of insulin on glucose uptake and storage by the liver.

A. Cherrington, D. Neal, Ben Farmer, 2002, Diabetes.

Simulated first-phase insulin release using Humulin or insulin analog HIM2 is associated with prolonged improvement in postprandial glycemia.

A. Cherrington, M. Scott, Ben Farmer, 2005, American journal of physiology. Endocrinology and metabolism.

The kinetics of glucagon action on the liver during insulin-induced hypoglycemia.

D. Edgerton, A. Cherrington, Phillip E. Williams, 2020, American journal of physiology. Endocrinology and metabolism.

Hepatic glycogen can regulate hypoglycemic counterregulation via a liver-brain axis.

D. Edgerton, E. Donahue, A. Cherrington, 2016, The Journal of clinical investigation.

Portal infusion of a selective serotonin reuptake inhibitor enhances hepatic glucose disposal in conscious dogs.

D. Dardevet, A. Cherrington, D. Neal, 2004, American journal of physiology. Endocrinology and metabolism.

Unlike mice, dogs exhibit effective glucoregulation during low-dose portal and peripheral glucose infusion.

D. Edgerton, A. Cherrington, D. Neal, 2004, American journal of physiology. Endocrinology and metabolism.

Effects of intraportal exenatide on hepatic glucose metabolism in the conscious dog.

D. Edgerton, A. Cherrington, D. Neal, 2013, American journal of physiology. Endocrinology and metabolism.

Interaction Between the Central and Peripheral Effects of Insulin in Controlling Hepatic Glucose Metabolism in the Conscious Dog

D. Edgerton, E. Donahue, A. Cherrington, 2012, Diabetes.

Intraportal GLP-1 infusion increases nonhepatic glucose utilization without changing pancreatic hormone levels.

D. Edgerton, A. Cherrington, M. Scott, 2007, American journal of physiology. Endocrinology and metabolism.

Glucose autoregulation is the dominant component of the hormone-independent counterregulatory response to hypoglycemia in the conscious dog.

D. Edgerton, E. Donahue, A. Cherrington, 2017, American journal of physiology. Endocrinology and metabolism.

Title : Glucose Autoregulation is the Dominant Component of the Hormone-Independent 1 Counterregulatory Response to Hypoglycemia in the Conscious Dog 2 Running head : Hormone-Independent Hypoglycemia Counterregulation 3

Cherrington, D. Edgerton, E. Donahue, 2017 .

Running title: Peripheral Insulin Delivery and Hypoglycemia

D. Edgerton, E. Donahue, J. Gregory, 2015 .

Hepatic Glucose Metabolism in Late Pregnancy

P. Roach, Phillip E. Williams, Ben Farmer, 2013, Diabetes.

Diet-induced impaired glucose tolerance and gestational diabetes in the dog.

M. Gannon, Phillip E. Williams, Ben Farmer, 2011, Journal of applied physiology.

gestational diabetes in the dog Diet-induced impaired glucose tolerance and

M. Gannon, Phillip E. Williams, Ben Farmer, 2011 .

Glucagon's actions are modified by the combination of epinephrine and gluconeogenic precursor infusion.

P. Flakoll, E. Donahue, S. Vaughan, 2003, American journal of physiology. Endocrinology and metabolism.

Hepatic and Whole-Body Insulin Metabolism during Proestrus and Estrus in Mongrel Dogs.

D. Edgerton, A. Cherrington, Phillip E. Williams, 2016, Comparative medicine.

Liver glycogen-induced enhancements in hypoglycemic counterregulation require neuroglucopenia.

D. Edgerton, S. Warner, Ben Farmer, 2021, American journal of physiology. Endocrinology and metabolism.

A fall in portal vein insulin does not cause the alpha-cell response to mild, non-insulin-induced hypoglycemia in conscious dogs.

A. Cherrington, A. Powers, D. Neal, 2003, Metabolism: clinical and experimental.

Safety of surgical denervation of the common hepatic artery in insulin‐resistant dogs

D. Edgerton, A. Cherrington, G. Kraft, 2021, Physiological reports.

A physiological increase in the hepatic glycogen level does not affect the response of net hepatic glucose uptake to insulin.

A. Cherrington, Ben Farmer, J. J. Winnick, 2009, American journal of physiology. Endocrinology and metabolism.

Hepatic portal venous delivery of a nitric oxide synthase inhibitor enhances net hepatic glucose uptake.

A. Cherrington, Phillip E. Williams, D. Neal, 2008, American journal of physiology. Endocrinology and metabolism.

A Soluble Guanylate Cyclase–Dependent Mechanism Is Involved in the Regulation of Net Hepatic Glucose Uptake by Nitric Oxide in Vivo

P. Roach, A. Cherrington, D. Neal, 2010, Diabetes.

Endogenously released GLP-1 is not sufficient to alter postprandial glucose regulation in the dog

E. Donahue, A. Cherrington, D. Neal, 2011, Endocrine.

Interaction of a selective serotonin reuptake inhibitor with insulin in the control of hepatic glucose uptake in conscious dogs.

D. Dardevet, A. Cherrington, Ben Farmer, 2005, American journal of physiology. Endocrinology and metabolism.

Portal serotonin infusion and glucose disposal in conscious dogs.

A. Cherrington, D. Neal, Ben Farmer, 2004, Diabetes.

A New Animal Model of Insulin-Glucose Dynamics in the Intraperitoneal Space Enhances Closed-Loop Control Performance.

Don Cohen, Eyal Dassau, Francis J. Doyle, 2019, Journal of process control.

Insulin Infusion Is Linked to Increased NPPC Expression in Muscle and Plasma C-type Natriuretic Peptide in Male Dogs

Christopher S. Wilson, A. Cherrington, J. Gregory, 2021, Journal of the Endocrine Society.

Priming Effect of a Morning Meal on Hepatic Glucose Disposition Later in the Day

A. Cherrington, G. Kraft, Ben Farmer, 2017, Diabetes.

The Importance of the Mechanisms by Which Insulin Regulates Meal-Associated Liver Glucose Uptake in the Dog

D. Edgerton, A. Cherrington, G. Kraft, 2021, Diabetes.

Bromocriptine Mesylate Improves Glucose Tolerance and Disposal in a High-Fat-Fed Canine Model.

A. Cincotta, A. Cherrington, Ben Farmer, 2020, American journal of physiology. Endocrinology and metabolism.

hepatocytesrelease and decrease glucokinase in Sucrose diets increase glucose-6-phosphatase and

P. Roach, G. Kraft, D. Neal, 2015 .

Diet-induced impaired glucose tolerance and gestational diabetes in the dog.

M. Gannon, Ben Farmer, K. Coate, 2011, Journal of applied physiology.

Chronic consumption of a high-fat/high-fructose diet renders the liver incapable of net hepatic glucose uptake.

A. Cherrington, M. Scott, D. Neal, 2010, American journal of physiology. Endocrinology and metabolism.

Integration of metabolic flux with hepatic glucagon signaling and gene expression profiles in the conscious dog.

D. Edgerton, E. Donahue, A. Cherrington, 2024, American journal of physiology. Endocrinology and metabolism.

Integration of metabolic flux with hepatic glucagon signaling and gene expression profiles in the conscious dog

D. Edgerton, A. Cherrington, G. Kraft, 2023, bioRxiv.