F. Palm

发表

Renal and vascular benefits of C-peptide: Molecular mechanisms of C-peptide action

L. Nordquist, F. Palm, B. Andresen, 2008, Biologics : targets & therapy.

A Model of Mitochondrial O2 Consumption and ATP Generation in Rat Proximal Tubule Cells.

A. Layton, F. Palm, A. Edwards, 2019, American journal of physiology. Renal physiology.

Bacterial infection‐mediated mucosal signalling induces local renal ischaemia as a defence against sepsis

B. Molitoris, J. Boekel, F. Palm, 2008, Cellular microbiology.

Metformin attenuates renal medullary hypoxia in diabetic nephropathy through inhibition uncoupling protein‐2

F. Palm, R. Nørregaard, Michael Christensen, 2018, Diabetes/metabolism research and reviews.

Metabolite aberrations in early diabetes detected in rat kidney using mass spectrometry imaging

Ingela Lanekoff, J. Kihlberg, F. Palm, 2019, Analytical and Bioanalytical Chemistry.

Reduced adenosine A2a receptor-mediated efferent arteriolar vasodilation contributes to diabetes-induced glomerular hyperfiltration.

F. Palm, P. Persson, P. Hansell, 2015, Kidney international.

Renal oxidative stress, oxygenation, and hypertension.

L. Nordquist, F. Palm, 2011, American journal of physiology. Regulatory, integrative and comparative physiology.

Inhibition of hyaluronan synthesis in rats reduces renal ability to excrete fluid and electrolytes during acute hydration

F. Palm, P. Hansell, S. Stridh, 2013, Upsala journal of medical sciences.

Promoting islet cell function after transplantation

G. Mattsson, N. Welsh, C. Carlsson, 2007, Cell Biochemistry and Biophysics.

Repetitive measurements of intrarenal oxygenation in vivo using L band electron paramagnetic resonance.

F. Palm, N. Khan, H. Gustafsson, 2014, Advances in experimental medicine and biology.

Chronically decreased oxygen tension in rat pancreatic islets transplanted under the kidney capsule.

P. Liss, P. Carlsson, F. Palm, 2000, Transplantation.

The effects of carbon dioxide versus ioxaglate in the rat kidney.

P. Liss, P. Carlsson, D. Bergqvist, 2005, Journal of vascular and interventional radiology : JVIR.

Uncoupling protein-2 in diabetic kidneys: increased protein expression correlates to increased non-transport related oxygen consumption.

P. Liss, F. Palm, P. Hansell, 2008, Advances in experimental medicine and biology.

Hyperbaric oxygen therapy reduces renal lactate production

C. Laustsen, Haiyun Qi, F. Palm, 2017, Physiological reports.

Renoprotective Effects of C-Peptide on Type 1 Diabetes

J. Wahren, L. Nordquist, F. Palm, 2012 .

Intrarenal activation of endothelin type B receptors improves kidney oxygenation in type 1 diabetic rats.

F. Palm, S. Franzén, L. Pihl, 2018, American journal of physiology. Renal physiology.

Endothelin type A receptor inhibition normalises intrarenal hypoxia in rats used as a model of type 1 diabetes by improving oxygen delivery

F. Palm, S. Franzén, 2015, Diabetologia.

High Intrarenal Lactate Production Inhibits the Renal Pseudohypoxic Response to Acutely Induced Hypoxia in Diabetes

J. Ardenkjær-Larsen, A. Flyvbjerg, C. Laustsen, 2019, Tomography.

Diabetes-induced alterations in renal medullary microcirculation and metabolism.

L. Nordquist, F. Palm, 2007, Current diabetes reviews.

diabetesnephropathy in four mouse strains with type 1 Differences in susceptibility to develop parameters of

M. Nangaku, F. Palm, P. Hansell, 2016 .

Differences in susceptibility to develop parameters of diabetic nephropathy in four mouse strains with type 1 diabetes.

M. Nangaku, F. Palm, P. Hansell, 2014, American journal of physiology. Renal physiology.

The dark side of angiotensin II: direct dynamic regulation of the glomerular filtration barrier permeability to macromolecules.

F. Palm, 2012, American journal of physiology. Renal physiology.

Intravoxel incoherent motion MR imaging of the kidney: pilot study.

P. Liss, Per Eckerbom, F. Palm, 2013, Advances in experimental medicine and biology.

Reduced oxygenation in diabetic rat kidneys measured by T2* weighted magnetic resonance micro-imaging.

P. Liss, J. Glickson, F. Palm, 2009, Advances in experimental medicine and biology.

Evaluation of regional renal blood flow with non-invasive ASL measurements compared with Gadolinium in patients before renal nephrectomy

S. Francis, P. Liss, E. Cox, 2014 .

pH is decreased in transplanted rat pancreatic islets.

P. Carlsson, F. Palm, A. Nordin, 2003, American journal of physiology. Endocrinology and metabolism.

Activation of hypoxia-inducible factors prevents diabetic nephropathy.

M. Nangaku, P. Liss, L. Nordquist, 2015, Journal of the American Society of Nephrology : JASN.

Renal tubulointerstitial hypoxia: Cause and consequence of kidney dysfunction

L. Nordquist, F. Palm, 2011, Clinical and experimental pharmacology & physiology.

Pharmacological HIF‐PHD inhibition reduces renovascular resistance and increases glomerular filtration by stimulating nitric oxide generation

M. Burmakin, V. Haase, F. Palm, 2021, Acta physiologica.

Repression of hypoxia-inducible factor-1 contributes to increased mitochondrial reactive oxygen species production in diabetes

P. Carmeliet, S. Catrina, L. Bernardi, 2021, bioRxiv.

Kidney outer medulla mitochondria are more efficient compared with cortex mitochondria as a strategy to sustain ATP production in a suboptimal environment.

F. Palm, Tomas A. Schiffer, H. Gustafsson, 2018, American journal of physiology. Renal physiology.

Pancreatic islet blood flow and its measurement

M. Sandberg, P. Carlsson, D. Espes, 2016, Upsala journal of medical sciences.

The effect of inactin on kidney mitochondrial function and production of reactive oxygen species

F. Palm, Michael Christensen, Tomas A. Schiffer, 2018, PloS one.

Acute Knockdown of Uncoupling Protein-2 Increases Uncoupling via the Adenine Nucleotide Transporter and Decreases Oxidative Stress in Diabetic Kidneys

S. Aslam, W. Welch, L. Nordquist, 2012, PloS one.

Hypoxia-inducible factor activation in diabetic kidney disease

F. Palm, P. Persson, Patrik Persson, 2017, Current opinion in nephrology and hypertension.

Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1358 Diabetes-induced Alterations in Renal Microcirculation and Metabolism

F. Palm, 2004 .

Role of nitric oxide deficiency in the development of hypertension in hydronephrotic animals.

F. Palm, T. Teerlink, Russell D. Brown, 2008, American journal of physiology. Renal physiology.

Glucose-regulated pulsatile insulin release from mouse islets via the K(ATP) channel-independent pathway.

P. Bergsten, F. Palm, J. Westerlund, 2001, European journal of endocrinology.

Expression of NG,NG-Dimethylarginine Dimethylaminohydrolase and Protein Arginine N-Methyltransferase Isoforms in Diabetic Rat Kidney

Maristela L Onozato, M. Onozato, J. Leiper, 2008, Diabetes.

Acute SGLT inhibition normalizes O2 tension in the renal cortex but causes hypoxia in the renal medulla in anaesthetized control and diabetic rats.

F. Palm, J. O’Neill, S. Franzén, 2015, American journal of physiology. Renal physiology.

Inhibition of mTOR activity in diabetes mellitus reduces proteinuria but not renal accumulation of hyaluronan

Tomoko Takahashi, F. Palm, P. Hansell, 2015, Upsala journal of medical sciences.

Combining sodium-dependent glucose co-transporter 2 inhibition with conventional diuretics: Dr Jekyll and Mr Hyde?

F. Palm, J. Joles, 2016, Journal of hypertension.

Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK.

Xuan Wang, N. Welsh, K. Turpaev, 2021, Clinical science.

Uremia induces abnormal oxygen consumption in tubules and aggravates chronic hypoxia of the kidney via oxidative stress.

Tetsuhiro Tanaka, M. Nangaku, T. Fujita, 2010, American journal of physiology. Renal physiology.

Differentiating between effects of streptozotocin per se and subsequent hyperglycemia on renal function and metabolism in the streptozotocin‐diabetic rat model

P. Liss, P. Carlsson, F. Palm, 2004, Diabetes/metabolism research and reviews.

Identification and distribution of uncoupling protein isoforms in the normal and diabetic rat kidney.

L. Nordquist, F. Palm, M. Johansson, 2009, Advances in experimental medicine and biology.

Effects of the antioxidant drug tempol on renal oxygenation in mice with reduced renal mass.

Maristela L Onozato, S. Aslam, M. Onozato, 2012, American journal of physiology. Renal physiology.

Diabetes-induced up-regulation of uncoupling protein-2 results in increased mitochondrial uncoupling in kidney proximal tubular cells.

L. Nordquist, F. Palm, P. Hansell, 2008, Biochimica et biophysica acta.

Unaltered oxygen tension in rat pancreatic islets despite dissociation of insulin release and islet blood flow.

P. Carlsson, F. Palm, L. Jansson, 2002, Acta physiologica Scandinavica.

Oxygen tension in isolated transplanted rat islets and in islets of rat whole‐pancreas transplants

P. Carlsson, F. Palm, 2002 .

Ex vivo hyperpolarized MR spectroscopy on isolated renal tubular cells: A novel technique for cell energy phenotyping

C. Laustsen, F. Palm, L. B. Bertelsen, 2017, Magnetic resonance in medicine.

Intrarenal oxygenation determines kidney function during the recovery from an ischemic insult.

F. Palm, P. Hansell, Oskar Nensén, 2020, American journal of physiology. Renal physiology.

Nitric oxide in afferent arterioles after uninephrectomy depends on extracellular L-arginine.

D. Schwartz, F. Palm, M. Hultström, 2013, American journal of physiology. Renal physiology.

Iodinated contrast media inhibit oxygen consumption in freshly isolated proximal tubular cells from elderly humans and diabetic rats: Influence of nitric oxide

P. Liss, F. Palm, P. Hansell, 2016, Upsala journal of medical sciences.

Renal oxygenation and function of the rat kidney: effects of inspired oxygen and preglomerular oxygen shunting.

W. Welch, F. Palm, C. Wilcox, 2013, Advances in experimental medicine and biology.

Angiotensin II-induced contraction is attenuated by nitric oxide in afferent arterioles from the nonclipped kidney in 2 K 1 C

F. Palm, M. Hultström, B. Iversen, 2008 .

Angiotensin II-induced contraction is attenuated by nitric oxide in afferent arterioles from the nonclipped kidney in 2K1C.

F. Palm, M. Hultström, B. Iversen, 2009, American journal of physiology. Renal physiology.

Blood Pressure, Blood Flow, and Oxygenation in the Clipped Kidney of Chronic 2-Kidney, 1-Clip Rats: Effects of Tempol and Angiotensin Blockade

Maristela L Onozato, M. Onozato, W. Welch, 2010, Hypertension.

Simultaneous determination of asymmetric and symmetric dimethylarginine, L-monomethylarginine, L-arginine, and L-homoarginine in biological samples using stable isotope dilution liquid chromatography tandem mass spectrometry.

H. Blom, M. Davids, P. Scheffer, 2012, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

High altitude may alter oxygen availability and renal metabolism in diabetics as measured by hyperpolarized [1-(13)C]pyruvate magnetic resonance imaging.

B. Bibby, J. Ardenkjaer-Larsen, A. Flyvbjerg, 2014, Kidney international.

Diabetes, oxidative stress, nitric oxide and mitochondria function.

F. Palm, P. Hansell, Malou Friederich, 2009, Current diabetes reviews.

Inhibition of mammalian target of rapamycin decreases intrarenal oxygen availability and alters glomerular permeability.

F. Palm, B. Rippe, P. Hansell, 2018, American journal of physiology. Renal physiology.

Reduced nitric oxide in diabetic kidneys due to increased hepatic arginine metabolism: implications for renomedullary oxygen availability.

P. Liss, P. Carlsson, F. Palm, 2008, American journal of physiology. Renal physiology.

Antioxidant treatment attenuates lactate production in diabetic nephropathy.

J. Ardenkjær-Larsen, H. Stødkilde-Jørgensen, A. Flyvbjerg, 2017, American journal of physiology. Renal physiology.

KIDNEY HYPOXIA , DUE TO INCREASED OXYGEN CONSUMPTION , INDUCES NEPHROPATHY INDEPENDENTLY OF HYPERGLYCEMIA AND OXIDATIVE STRESS

M. Nangaku, F. Palm, P. Hansell, 2013 .

Pronounced kidney hypoxia precedes albuminuria in type 1 diabetic mice.

F. Palm, N. Khan, H. Gustafsson, 2016, American journal of physiology. Renal physiology.

Editorial: Hypoxia in Kidney Disease

F. Palm, M. Koeners, 2018, Front. Physiol..

Role of carbonic anhydrase in acute recovery following renal ischemia reperfusion injury

F. Palm, P. Hansell, Oskar Nensén, 2017, PloS one.

Angiotensin II Type 2 Receptors and Nitric Oxide Sustain Oxygenation in the Clipped Kidney of Early Goldblatt Hypertensive Rats

W. Welch, F. Palm, C. Wilcox, 2008, Hypertension.

Nitric oxide originating from NOS1 controls oxygen utilization and electrolyte transport efficiency in the diabetic kidney.

F. Palm, O. Källskog, P. Hansell, 2010, American journal of physiology. Renal physiology.

Increased kidney metabolism as a pathway to kidney tissue hypoxia and damage: effects of triiodothyronine and dinitrophenol in normoglycemic rats.

L. Nordquist, F. Palm, P. Persson, 2013, Advances in experimental medicine and biology.

Renal oxygenation during haemorrhage is not aggravated by angiotensin II AT1‐receptor blockade

F. Palm, J. Melville, M. Hultström, 2016, Acta physiologica.

Low revascularization of experimentally transplanted human pancreatic islets.

G. Mattsson, P. Carlsson, F. Palm, 2002, The Journal of clinical endocrinology and metabolism.

The roles of NADPH‐oxidase and nNOS for the increased oxidative stress and the oxygen consumption in the diabetic kidney

P. Liss, F. Palm, P. Hansell, 2010, Diabetes/metabolism research and reviews.

Altered response in renal blood flow and oxygen tension to contrast media in diabetic rats.

P. Liss, P. Carlsson, F. Palm, 2003, Acta radiologica.

Effects of the contrast medium iopromide on renal hemodynamics and oxygen tension in the diabetic rat kidney.

P. Liss, P. Carlsson, F. Palm, 2003, Advances in experimental medicine and biology.

Iodinated contrast media decrease renomedullary blood flow. A possible cause of contrast media-induced nephropathy.

P. Liss, P. Carlsson, F. Palm, 2009, Advances in experimental medicine and biology.

Working the Self: Truth-Telling in the Practice of Alcoholics Anonymous

F. Palm, 2021, Human Studies.

Hyaluronan Production by Renomedullary Interstitial Cells: Influence of Endothelin, Angiotensin II and Vasopressin

Tomoko Takahashi, F. Palm, P. Hansell, 2017, International journal of molecular sciences.

Unyoking Sexual Difference: Law, Universality, and the Excluded Other

F. Palm, 2016 .

Renal interstitial hyaluronan: functional aspects during normal and pathological conditions.

F. Palm, P. Hansell, S. Stridh, 2012, American journal of physiology. Regulatory, integrative and comparative physiology.

Markedly decreased oxygen tension in transplanted rat pancreatic islets irrespective of the implantation site.

P. Liss, P. Carlsson, F. Palm, 2001, Diabetes.

Dimethylarginine dimethylaminohydrolase (DDAH): expression, regulation, and function in the cardiovascular and renal systems.

Maristela L Onozato, M. Onozato, F. Palm, 2007, American journal of physiology. Heart and circulatory physiology.

Acute renal metabolic effect of metformin assessed with hyperpolarised MRI in rats

C. Laustsen, Haiyun Qi, F. Palm, 2018, Diabetologia.

Tubular reabsorption and diabetes‐induced glomerular hyperfiltration

F. Palm, P. Persson, P. Hansell, 2010, Acta physiologica.

Proinsulin C-peptide reduces diabetes-induced glomerular hyperfiltration via efferent arteriole dilation and inhibition of tubular sodium reabsorption.

L. Nordquist, F. Palm, Russell D. Brown, 2009, American journal of physiology. Renal physiology.

Kidney Hypoxia, Attributable to Increased Oxygen Consumption, Induces Nephropathy Independently of Hyperglycemia and Oxidative Stress

M. Nangaku, F. Palm, P. Hansell, 2013, Hypertension.

Acute intrarenal angiotensin (1‐7) infusion decreases diabetes‐induced glomerular hyperfiltration but increases kidney oxygen consumption in the rat

F. Palm, P. Persson, A. Fasching, 2019, Acta physiologica.

Cellular ADMA: regulation and action.

F. Palm, T. Teerlink, C. Wilcox, 2009, Pharmacological research.

Oxidative Stress and Hypoxia in the Pathogenesis of Diabetic Nephropathy

L. Nordquist, F. Palm, P. Hansell, 2011 .

Multiparametric assessment of renal physiology in healthy volunteers using noninvasive magnetic resonance imaging.

S. Francis, P. Liss, E. Cox, 2019, American journal of physiology. Renal physiology.

NADPH oxidase inhibition reduces tubular sodium transport and improves kidney oxygenation in diabetes.

F. Palm, P. Persson, P. Hansell, 2012, American journal of physiology. Regulatory, integrative and comparative physiology.

Oxygen Transport to Tissue XXXIV

D. Bruley, W. Welch, D. Harrison, 2014, Advances in Experimental Medicine and Biology.

Determinants of kidney oxygen consumption and their relationship to tissue oxygen tension in diabetes and hypertension

Fredrik Palm, Peter Hansell, W. Welch, 2013, Clinical and experimental pharmacology & physiology.

L-Citrulline, But Not L-Arginine, Prevents Diabetes Mellitus–Induced Glomerular Hyperfiltration and Proteinuria in Rat

F. Palm, T. Teerlink, P. Persson, 2014, Hypertension.

Reduced nitric oxide concentration in the renal cortex of streptozotocin-induced diabetic rats: effects on renal oxygenation and microcirculation.

D. Buerk, P. Liss, P. Carlsson, 2005, Diabetes.

Nitric oxide in the kidney; direct measurements of bioavailable renal nitric oxide.

D. Buerk, L. Nordquist, F. Palm, 2007, Advances in experimental medicine and biology.

Angiotensin II contributes to glomerular hyperfiltration in diabetic rats independently of adenosine type I receptors.

F. Palm, D. Pinho, M. Morato, 2013, American journal of physiology. Renal physiology.

Thick ascending tubular cells in the loop of Henle: regulation of electrolyte homeostasis.

P. Carlsson, F. Palm, 2005, The international journal of biochemistry & cell biology.

Angiotensin II reduces transport-dependent oxygen consumption but increases transport-independent oxygen consumption in immortalized mouse proximal tubular cells.

W. Welch, L. Nordquist, F. Palm, 2014, Advances in experimental medicine and biology.

Cellular transport of l-arginine determines renal medullary blood flow in control rats, but not in diabetic rats despite enhanced cellular uptake capacity.

F. Palm, T. Teerlink, P. Persson, 2017, American journal of physiology. Renal physiology.

Deletion of Uncoupling Protein‐2 reduces renal mitochondrial leak respiration, intrarenal hypoxia and proteinuria in a mouse model of type 1 diabetes

F. Palm, P. Persson, P. Hansell, 2018, Acta physiologica.

Modulation of Shigella virulence in response to available oxygen in vivo

J. A. Cole, M. Prevost, P. Sansonetti, 2010, Nature.

INTRARENAL OXYGEN IN DIABETES AND A POSSIBLE LINK TO DIABETIC NEPHROPATHY

F. Palm, 2006, Clinical and experimental pharmacology & physiology.

Adenosine A2 receptor-mediated regulation of renal hemodynamics and glomerular filtration rate is abolished in diabetes.

F. Palm, P. Persson, P. Hansell, 2013, Advances in experimental medicine and biology.

Circadian variation in renal blood flow and kidney function in healthy volunteers monitored using non-invasive magnetic resonance imaging.

S. Francis, P. Liss, E. Cox, 2020, American journal of physiology. Renal physiology.

Determinants of renal oxygen metabolism during low Na+ diet: effect of angiotensin II AT1 and aldosterone receptor blockade

F. Palm, P. Persson, D. Patinha, 2020, The Journal of physiology.

15-Deoxy-Δ12,14-prostaglandin J2 Exerts Antioxidant Effects While Exacerbating Inflammation in Mice Subjected to Ureteral Obstruction

F. Palm, R. Nørregaard, L. Nilsson, 2017, Mediators of inflammation.

Mortality after radiotherapy or surgery in the treatment of early stage non-small-cell lung cancer: a population-based study on recent developments

R. Mikolajczyk, D. Vordermark, F. Palm, 2019, Journal of Cancer Research and Clinical Oncology.

Patients knowledge about caries prevention and oral hygiene - a comparative study

F. Palm, S. Karlsson, 2018 .

Insufficient insulin administration to diabetic rats increases substrate utilization and maintains lactate production in the kidney

J. Ardenkjær-Larsen, A. Flyvbjerg, C. Laustsen, 2014, Physiological reports.

Mitochondrial Respiration-Dependent ANT2-UCP2 Interaction

F. Palm, M. Kamali-Moghaddam, M. Carlström, 2022, Frontiers in Physiology.

Introduction: Why Death Matters

T. Holmberg, F. Palm, Annika Jonsson, 2019, Death Matters.

Early transcriptional regulation by C‐peptide in freshly isolated rat proximal tubular cells

K. Dahlman-Wright, H. Jörnvall, L. Nordquist, 2011, Diabetes/metabolism research and reviews.

Adenosine A1 receptors in contrast media-induced renal dysfunction in the normal rat

P. Liss, P. Carlsson, F. Palm, 2004, European Radiology.

The use of hydrogen gas clearance for blood flow measurements in single endogenous and transplanted pancreatic islets.

M. Sandberg, F. Palm, L. Jansson, 2015, Microvascular research.

Hypoxia in the diabetic kidney is independent of advanced glycation end-products.

P. Liss, L. Nordquist, F. Palm, 2013, Advances in experimental medicine and biology.

Sexual Arousal, Danger, and Vulnerability

F. Palm, 2016 .

Kidney function after in vivo gene silencing of uncoupling protein-2 in streptozotocin-induced diabetic rats.

W. Welch, F. Palm, C. Wilcox, 2013, Advances in experimental medicine and biology.

Engraftment and Growth of Transplanted Pancreatic Islets

G. Mattsson, P. Liss, C. Carlsson, 2000, Upsala Journal of Medical Sciences.

Oxygen tension in isolated transplanted rat islets and in islets of rat whole-pancreas transplants

P. Carlsson, F. Palm, 2002, Transplant international : official journal of the European Society for Organ Transplantation.

Insulin induces the correlation between renal blood flow and glomerular filtration rate in diabetes: implications for mechanisms causing hyperfiltration.

G. Dibona, F. Palm, P. Persson, 2012, American journal of physiology. Regulatory, integrative and comparative physiology.

Nitric oxide and kidney oxygenation

F. Palm, T. Teerlink, P. Hansell, 2009, Current opinion in nephrology and hypertension.

Introduction

F. Palm, 2013, Clinical and Experimental Pharmacology and Physiology.

Frontiers in Research Reviews: Kidney Oxygenation in Health and Disease Introduction

F. Palm, 2013 .