Hyeong-Seok Lim

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A variant 2677A allele of the MDR1 gene affects fexofenadine disposition

D. Oh, Joo-Youn Cho, K. Yu, 2004, Clinical pharmacology and therapeutics.

Effects of ketoconazole and rifampicin on the pharmacokinetics of gemigliptin, a dipeptidyl peptidase-IV inhibitor: a crossover drug-drug interaction study in healthy male Korean volunteers.

Hyeong-Seok Lim, Yook-Hwan Noh, Seok-Joon Jin, 2012, Clinical therapeutics.

Population pharmacokinetics of HM781-36 (poziotinib), pan-human EGF receptor (HER) inhibitor, and its two metabolites in patients with advanced solid malignancies

Hyeong-Seok Lim, Yook-Hwan Noh, K. Bae, 2014, Cancer Chemotherapy and Pharmacology.

Population plasma and urine pharmacokinetics of ivabradine and its active metabolite S18982 in healthy Korean volunteers

Sang-Heon Cho, S. Choe, Hyeong-Seok Lim, 2016, Journal of clinical pharmacology.

Modeling and simulation to predict the degree of disability over time in acute ischemic stroke patients

Sang-In Park, D. Kang, Hyeong-Seok Lim, 2021, Clinical and translational science.

Increased Expression of Metallothionein Is Associated with Irinotecan Resistance in Gastric Cancer

Hyeong-Seok Lim, Il-Jin Kim, Jae-Hyun Park, 2004, Cancer Research.

Bioavailability and tolerability of combination treatment with revaprazan 200 mg + itopride 150 mg: a randomized crossover study in healthy male Korean volunteers.

Hyeong-Seok Lim, S. Jang, Yook-Hwan Noh, 2012, Clinical therapeutics.

Human papillomavirus in breast carcinomas of Korean women.

Hyeong-Seok Lim, J. W. Lee, S. Nam, 2009 .

Whole-Body Physiologically Based Pharmacokinetic Modeling of Trastuzumab and Prediction of Human Pharmacokinetics.

Dong-Jun Bae, Sang-Yeob Kim, S. Bae, 2019, Journal of pharmaceutical sciences.

Predicting Overall Survival and Progression-Free Survival Using Tumor Dynamics in Advanced Breast Cancer Patients

Hyeong-Seok Lim, Diane D. Wang, K. Parivar, 2019, The AAPS Journal.

Pharmacokinetic Evaluation by Modeling and Simulation Analysis of a Donepezil Patch Formulation in Healthy Male Volunteers

Hyeong-Seok Lim, K. Bae, SeokKyu Yoon, 2020, Drug design, development and therapy.

Pharmacokinetic interactions and tolerability of rosuvastatin and ezetimibe: an open-label, randomized, multiple-dose, crossover study in healthy male volunteers

Hyungsub Kim, Hyeong-Seok Lim, H. Choi, 2018, Drug design, development and therapy.

Integrated pharmacogenetic prediction of irinotecan pharmacokinetics and toxicity in patients with advanced non-small cell lung cancer.

Ji-Youn Han, J. S. Lee, Hyeong-Seok Lim, 2009, Lung cancer.

Randomized Phase II study of two opposite administration sequences of irinotecan and cisplatin in patients with advanced nonsmall cell lung carcinoma

Hyae-Young Kim, Dae-Ho Lee, Ji-Youn Han, 2006, Cancer.

A Simulation Study to Compare the Treatment Effect of Tamoxifen by CYP2D6 Genotypes and Third‐Generation Aromatase Inhibitors

Hyeong-Seok Lim, K. Bae, J. Jung, 2017, Journal of clinical pharmacology.

Association of CYP2A6 polymorphisms with S-1 plus docetaxel therapy outcomes in metastatic gastric cancer.

I. Choi, M. Kook, Young-Woo Kim, 2009, Pharmacogenomics.

Quantitative Modeling Analysis Demonstrates the Impact of CYP2C19 and CYP2D6 Genetic Polymorphisms on the Pharmacokinetics of Amitriptyline and Its Metabolite, Nortriptyline

A. Koh, Hyeong-Seok Lim, H. Choi, 2018, Journal of clinical pharmacology.

Effect of the CYP3A5 genotype on the pharmacokinetics of intravenous midazolam during inhibited and induced metabolic states

D. Oh, Kwang-Hyeon Liu, Joo-Youn Cho, 2004, Clinical pharmacology and therapeutics.

First-in-Human Evaluation of the Safety, Tolerability, and Pharmacokinetics of a Neuroprotective Poly (ADP‐ribose) Polymerase‐1 Inhibitor, JPI-289, in Healthy Volunteers

Hyeong-Seok Lim, Yo Han Kim, H. Choi, 2020, Drug design, development and therapy.

Evaluation of pharmacokinetic and pharmacodynamic profiles and tolerability after single (2.5, 5, or 10 mg) and repeated (2.5, 5, or 10 mg bid for 4.5 days) oral administration of ivabradine in healthy male Korean volunteers.

Sang-Heon Cho, S. Choe, Hyeong-Seok Lim, 2013, Clinical therapeutics.

Dose proportionality and pharmacokinetics of carvedilol sustained-release formulation: a single dose-ascending 10-sequence incomplete block study

Hyeong-Seok Lim, Yook-Hwan Noh, Yo Han Kim, 2015, Drug design, development and therapy.

A phase 1 dose-escalation and dose-expansion study to assess the safety and efficacy of CKD-516, a novel vascular disrupting agent, in combination with Irinotecan in patients with previously treated metastatic colorectal cancer

Tae Won Kim, Tae-You Kim, Hyeong-Seok Lim, 2021, Investigational New Drugs.

Phase I clinical and pharmacokinetic/pharmacogenetic study of a triplet regimen of S-1/irinotecan/oxaliplatin in patients with metastatic colorectal or gastric cancer

K. Jung, M. Seong, S. Kong, 2013, Cancer Chemotherapy and Pharmacology.

CYP2A6 genetic polymorphism as a predictive marker for clinical outcomes in patients (pts) with metastastic gastric carcinoma (MGC) treated with S-1 plus docetaxel

Hoon-Kyo Kim, Hyeong-Seok Lim, Sook Ryun Park, 2007 .

Associations of ABCB1, ABCC2, and ABCG2 polymorphisms with irinotecan‐pharmacokinetics and clinical outcome in patients with advanced non‐small cell lung cancer

E. Shin, Yeon‐Kyeong Yoo, Heung Tae Kim, 2007, Cancer.

Impact of CYP2D6, CYP3A5, CYP2C19, CYP2A6, SLCO1B1, ABCB1, and ABCG2 gene polymorphisms on the pharmacokinetics of simvastatin and simvastatin acid

Sang-Heon Cho, S. Choe, Hyeong-Seok Lim, 2015, Pharmacogenetics and genomics.

Development of a validated liquid chromatography-tandem mass spectrometry assay for the quantification of simvastatin acid, the active metabolite of simvastatin, in human plasma

Sang-Heon Cho, S. Choe, Hyeong-Seok Lim, 2016 .

Pharmacokinetic and pharmacogenetic study of S-1 in Korean patients with metastatic biliary cancer.

Tae Won Kim, Jung Lim Lee, Hyeong-Seok Lim, 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Lack of any association between functionally significant CYP2D6 polymorphisms and clinical outcomes in early breast cancer patients receiving adjuvant tamoxifen treatment

H. Kang, Sohee Park, Hyeong-Seok Lim, 2011, Breast Cancer Research and Treatment.

A phase II study of perioperative S-1 combined with weekly docetaxel in patients with locally advanced gastric carcinoma: clinical outcomes and clinicopathological and pharmacogenetic predictors for survival

Hyeong-Seok Lim, Sun-Young Kong, Mi-Jung Kim, 2016, Gastric Cancer.

Bioequivalence of HCP1104, a New Fixed Dose Combination Drug and Co-administration of Eperisone 50 mg and Aceclofenac 100 mg: A Partial Replicated Crossover Study Design to Estimate the Pharmacokinetics of Highly Variable Drugs

Hyeong-Seok Lim, Yook-Hwan Noh, Mi Jo Kim, 2013 .

Pharmacokinetic interactions between eperisone hydrochloride and aceclofenac: a randomized, open-label, crossover study of healthy Korean men.

Hyeong-Seok Lim, K. Park, Yook-Hwan Noh, 2013, Clinical therapeutics.

Comparison of Pharmacokinetics and Safety of Two Formulations of Letrozole (2.5 mg) in Healthy Male Volunteers

Sang-Heon Cho, S. Choe, Hyeong-Seok Lim, 2012 .

Pharmacokinetic interaction of telmisartan with s-amlodipine: an open-label, two-period crossover study in healthy Korean male volunteers.

Hyeong-Seok Lim, Yook-Hwan Noh, Seok-Joon Jin, 2012, Clinical therapeutics.

Pharmacokinetic comparison of 2 formulations of anastrozole (1 mg) in healthy Korean male volunteers: a randomized, single-dose, 2-period, 2-sequence, crossover study.

Sang-Heon Cho, S. Choe, Hyeong-Seok Lim, 2012, Clinical therapeutics.

Comparative Pharmacokinetics and Bioavailability of Gemifloxacin Administered as an Intravenous 200 mg Formulation or an Oral 320 mg Tablet

Sang-Heon Cho, Hyeong-Seok Lim, Mi Jo Kim, 2014, Clinical Drug Investigation.

A phase I study of DHP107, a mucoadhesive lipid form of oral paclitaxel, in patients with advanced solid tumors: Crossover comparisons with intravenous paclitaxel

Tae Won Kim, H. Chang, Yoon-Koo Kang, 2013, Investigational New Drugs.

Single dose pharmacokinetics of the novel transdermal donepezil patch in healthy volunteers

Hyeong-Seok Lim, Yo Han Kim, H. Choi, 2015, Drug design, development and therapy.

Pharmacokinetic Equivalence of the High Dose Strength Fixed-Dose Combination Tablet of Gemigliptin/Metformin Sustained Release (SR) and Individual Component Gemigliptin and Metformin XR Tablets in Healthy Subjects

Yong-Soon Cho, Hyeong-Seok Lim, K. Bae, 2018, Journal of Korean medical science.

Pharmacokinetics and pharmacodynamics of ticagrelor and prasugrel in healthy male Korean volunteers.

Hyeong-Seok Lim, H. Choi, K. Bae, 2015, Clinical therapeutics.

Effects of Pregnane X Receptor (NR1I2) and CYP2B6 Genetic Polymorphisms on the Induction of Bupropion Hydroxylation by Rifampin

Joo-Youn Cho, K. Yu, Jae-Yong Chung, 2011, Drug Metabolism and Disposition.

Effect of Low-Dose Versus Standard-Dose Ticagrelor and Clopidogrel on Platelet Inhibition in Acute Coronary Syndromes.

Seung‐Jung Park, S. Yun, Duk‐Woo Park, 2018, Journal of the American College of Cardiology.

Pharmacokinetic and Pharmacodynamic Evaluation of Intravenous Levetiracetam in Children With Epilepsy

Hyeong-Seok Lim, M. Yum, T. Ko, 2018, Journal of clinical pharmacology.

Ethnic differences and relationships in the oral pharmacokinetics of nifedipine and erythromycin

Joo-Youn Cho, K. Yu, S. Yi, 2001, Clinical pharmacology and therapeutics.

Pharmacokinetic and Pharmacodynamic Evaluation of a Novel Proton Pump Inhibitor, YH1885, in Healthy Volunteers

Joo-Youn Cho, K. Yu, Jae-Yong Chung, 2004, Journal of clinical pharmacology.

Pharmacokinetics of Hydroxychloroquine and Its Clinical Implications in Chemoprophylaxis against Malaria Caused by Plasmodium vivax

Jae-Won Park, Joo-Youn Cho, T. Klein, 2009, Antimicrobial Agents and Chemotherapy.

Tolerability and pharmacokinetics of avanafil, a phosphodiesterase type 5 inhibitor: a single- and multiple-dose, double-blind, randomized, placebo-controlled, dose-escalation study in healthy Korean male volunteers.

Sang-Heon Cho, Hyeong-Seok Lim, K. Bae, 2010, Clinical therapeutics.

Belvarafenib, a novel pan-RAF inhibitor, in solid tumor patients harboring BRAF, KRAS, or NRAS mutations: Phase I study.

Tae Won Kim, Jeeyun Lee, Hyeong-Seok Lim, 2019, Journal of Clinical Oncology.

Pharmacokinetic and Pharmacodynamic Modeling and Simulation Analysis of CTB-001, a Recently Developed Generic of Bivalirudin

Hyeong-Seok Lim, H. Choi, K. Bae, 2019, Pharmaceutical Research.

Pharmacokinetic Evaluation by Modeling and Simulation Analysis of a Donepezil Patch Formulation in Healthy Male Volunteers

Hyeong-Seok Lim, K. Bae, SeokKyu Yoon, 2018, Alzheimer's & Dementia.

Pharmacokinetic modeling analysis of cilostazol and its active metabolites (OPC-13015 and OPC-13213) after multiple oral doses of cilostazol in healthy Korean volunteers

Sang-Heon Cho, S. Choe, Hyeong-Seok Lim, 2020, Xenobiotica; the fate of foreign compounds in biological systems.

Pharmacokinetic and Pharmacodynamic Modeling and Simulation Analysis of Prasugrel in Healthy Male Volunteers

Hyungsub Kim, Hyeong-Seok Lim, Sang-Min Lee, 2022, Clinical pharmacology in drug development.

Pharmacologic properties of high-dose ambroxol in four patients with Gaucher disease and myoclonic epilepsy

J. Tolar, A. Rolfs, H. Yoo, 2019, Journal of Medical Genetics.

First-in-human, double-blind, randomized controlled trial of an oral dose of GnRH antagonist, TU2670 in healthy women.

Hun-Taek Kim, Sang-Heon Cho, Yong-Soon Cho, 2020, The Journal of clinical endocrinology and metabolism.

Pharmacokinetic comparison of sustained- and immediate-release formulations of cilostazol after multiple oral doses in fed healthy male Korean volunteers

Sang-Heon Cho, S. Choe, Hyeong-Seok Lim, 2015, Drug design, development and therapy.

Comparison of Pharmacokinetic Characteristics and the Safety between Amlodipine Maleate Tablet 5 mg and Amlodipine Besylate Tablet 5 mg

Sang-Heon Cho, J. Kim, S. Choe, 2012 .

Pharmacokinetic Drug Interaction Between Amlodipine and Tadalafil: An Open-Label, Randomized, Multiple-Dose Crossover Study in Healthy Male Volunteers

Hyeong-Seok Lim, Hyungsu Kim, S. Lee, 2022, Drug design, development and therapy.

Effects of Renal Impairment on the Pharmacokinetics and Safety of Udenafil

Sang-Heon Cho, Yong-Soon Cho, S. Choe, 2018, Journal of clinical pharmacology.

Safety, tolerability and pharmacokinetics of udenafil, a novel PDE-5 inhibitor, in healthy young Korean subjects.

Joo-Youn Cho, K. Yu, Jae-Yong Chung, 2008, British journal of clinical pharmacology.

Therapeutic dosage assessment based on population pharmacokinetics of a novel single-dose transdermal donepezil patch in healthy volunteers

Hyeong-Seok Lim, Yo Han Kim, H. Choi, 2015, European Journal of Clinical Pharmacology.

Tolerability and Pharmacokinetics Following a Single Dose of Vardenafil in Healthy Korean Volunteers

K. Yu, Hyeong-Seok Lim, I. Jang, 2012 .

Effect of the CYP2D6 genotype on the pharmacokinetics of tropisetron in healthy Korean subjects

D. Oh, B. Min, Joo-Youn Cho, 2003, European Journal of Clinical Pharmacology.

Single and multiple dose pharmacokinetics and tolerability of HX-1171, a novel antioxidant, in healthy volunteers

Hyeong-Seok Lim, Kyoung-Goo Han, Yo Han Kim, 2015, Drug design, development and therapy.

Pharmacokinetic, tolerability, and bioequivalence comparison of three different intravenous formulations of recombinant human erythropoietin in healthy Korean adult male volunteers: an open-label, randomized-sequence, three-treatment, three-way crossover study.

Sang-Heon Cho, S. Choe, Hyeong-Seok Lim, 2009, Clinical therapeutics.

Tolerability and pharmacokinetics of two formulations of megestrol acetate under fed conditions in healthy volunteers.

Hyeong-Seok Lim, Yook-Hwan Noh, Mi Jo Kim, 2015, Clinical therapeutics.

Comparison of the Efficacy and Safety of a Pharmacokinetic Model-Based Dosing Scheme Versus a Conventional Fentanyl Dosing Regimen For Patient-Controlled Analgesia Immediately Following Robot-Assisted Laparoscopic Prostatectomy

Hyeong-Seok Lim, Seok-Joon Jin, Jai-hyun Hwang, 2016, Medicine.

Sensitive liquid chromatography assay with ultraviolet detection for a new phosphodiesterase V inhibitor, DA-8159, in human plasma and urine.

Joo-Youn Cho, K. Yu, Hyeong-Seok Lim, 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Pharmacokinetic interaction between udenafil and dapoxetine: a randomized, open-labeled crossover study in healthy male volunteers

Hyeong-Seok Lim, Yo Han Kim, H. Choi, 2015, Drug design, development and therapy.

Pharmacokinetic comparison of controlled- and immediate-release formulations of dexibuprofen after single and multiple oral doses in fasting healthy male Korean volunteers.

Sang-Heon Cho, S. Choe, Hyeong-Seok Lim, 2011, Clinical therapeutics.

Comparison of various estimation methods for the parameters of Michaelis-Menten equation based on in vitro elimination kinetic simulation data

Yong-Soon Cho, Hyeong-Seok Lim, 2018, Translational and clinical pharmacology.

HAPLOTYPE STRUCTURE AND ALLELE FREQUENCIES OF CYP2B6 IN A KOREAN POPULATION

Joo-Youn Cho, K. Yu, Hyeong-Seok Lim, 2004, Drug Metabolism and Disposition.

Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin.

E. Shin, Yeon‐Kyeong Yoo, Dae-Ho Lee, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

ARAF mutations confer resistance to the RAF inhibitor belvarafenib in melanoma

Z. Modrušan, Tae Won Kim, Matthew T. Chang, 2021, Nature.

Efficacy and Safety of a New 10% Intravenous Immunoglobulin Product in Patients with Primary Immune Thrombocytopenia (ITP)

Junshik Hong, H. Yhim, Hyeong-Seok Lim, 2018, Journal of Korean medical science.

Ventriculolumbar Perfusion Chemotherapy for the Treatment of Leptomeningeal Carcinomatosis: A Phase I Study With Pharmacokinetic Data

Heung Tae Kim, Ji-Youn Han, J. S. Lee, 2013, American journal of clinical oncology.

Influence of the organic anion-transporting polypeptide 1B1 (OATP1B1) polymorphisms on irinotecan-pharmacokinetics and clinical outcome of patients with advanced non-small cell lung cancer.

Hyeong-Seok Lim, E. Shin, Yeon‐Kyeong Yoo, 2008, Lung cancer.

Predicting Overall Survival and Progression-Free Survival Using Tumor Dynamics in Advanced Breast Cancer Patients

Hyeong-Seok Lim, Diane D. Wang, K. Parivar, 2019, The AAPS Journal.

Short report: chloroquine-resistant Plasmodium vivax in the Republic of Korea.

Jae-Won Park, Hyeong-Seok Lim, J. Yeom, 2009, The American journal of tropical medicine and hygiene.

Randomised clinical trial: safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple oral doses of tegoprazan (CJ‐12420), a novel potassium‐competitive acid blocker, in healthy male subjects

Hyeong-Seok Lim, Yo Han Kim, H. Choi, 2019, Alimentary pharmacology & therapeutics.

Prospective validation of a novel dosing scheme for intravenous busulfan in adult patients undergoing hematopoietic stem cell transplantation

Sang-Heon Cho, S. Choe, Hyeong-Seok Lim, 2016, The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology.

A Simple Dosing Scheme for Intravenous Busulfan Based on Retrospective Population Pharmacokinetic Analysis in Korean Patients

Sang-Heon Cho, S. Choe, Hyeong-Seok Lim, 2012, The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology.

Evaluation of the pharmacokinetics of the DPP-4 inhibitor gemigliptin when coadministered with rosuvastatin or irbesartan to healthy subjects

Hyeong-Seok Lim, Mi Jo Kim, Yo Han Kim, 2015, Current medical research and opinion.

Evaluation of Pharmacokinetic Drug Interactions Between Gemigliptin (Dipeptidylpeptidase-4 Inhibitor) and Glimepiride (Sulfonylurea) in Healthy Volunteers

Hyeong-Seok Lim, Mi Jo Kim, Yo Han Kim, 2014, Drugs in R&D.

Clinical implications of CYP2D6 genotypes predictive of tamoxifen pharmacokinetics in metastatic breast cancer.

Hyeong-Seok Lim, I. Jang, J. Ro, 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Single nucleotide polymorphism of Wilms’ tumor 1 gene rs16754 in Korean patients with cytogenetically normal acute myeloid leukemia

Yunsuk Choi, Hyeong-Seok Lim, Je-Hwan Lee, 2012, Annals of Hematology.

Postgastrectomy pharmacokinetic changes of S‐1 in patients with localized advanced gastric cancer

Young-Woo Kim, K. Ryu, J. Lee, 2015, Journal of clinical pharmacology.

Dynamic contrast‐enhanced MRI for oncology drug development

Hyeong-Seok Lim, Yu Sub Sung, Yoonseok Choi, 2016, Journal of magnetic resonance imaging : JMRI.

Angiotensin II type 1 receptor 1166A/C polymorphism in association with blood pressure response to exogenous angiotensin II

Hyeong-Seok Lim, Kyun-Seop Bae, Sang-Goo Shin, 2006, European Journal of Clinical Pharmacology.

Association between CYP2D6 genotypes and the clinical outcomes of adjuvant tamoxifen for breast cancer: a meta-analysis.

Hyeong-Seok Lim, Hyeong-Seok Lim, J. Jung, 2014, Pharmacogenomics.

Predicting the efficacy of an oral paclitaxel formulation (DHP107) through modeling and simulation.

Tae Won Kim, Yoon-Koo Kang, Hyeong-Seok Lim, 2015, Clinical therapeutics.

Influence of GST gene polymorphisms on the clearance of intravenous busulfan in adult patients undergoing hematopoietic cell transplantation.

S. Yun, G. Noh, S. Han, 2011, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Population Pharmacokinetic Analysis of Simvastatin and its Active Metabolite with the Characterization of Atypical Complex Absorption Kinetics

Sang-Heon Cho, S. Choe, Hyeong-Seok Lim, 2014, Pharmaceutical Research.

A Phase I/IIa Study of DHP107, a Novel Oral Paclitaxel Formulation, in Patients with Advanced Solid Tumors or Gastric Cancer

Tae Won Kim, Yoon-Koo Kang, Hyeong-Seok Lim, 2017, The oncologist.

Validation of LC-MS/MS Method for Determination of Bivalirudin in Human Plasma: Application to a Pharmacokinetic Study

Hyeong-Seok Lim, H. Park, Yo Han Kim, 2013 .

Pharmacokinetic equivalence of CT‐P17 to high‐concentration (100 mg/ml) reference adalimumab: A randomized phase I study in healthy subjects

D. Furst, K. Yu, Hyeong-Seok Lim, 2021, Clinical and translational science.

Pharmacokinetics, Tolerability, and Safety of the Single Oral Administration of AGSAV301 vs Exforge: A Randomized Crossover Study of Healthy Male Volunteers

Hyeong-Seok Lim, Yook-Hwan Noh, Mi Jo Kim, 2014, American Journal of Cardiovascular Drugs.

Single-dose Intravenous Safety, Tolerability, and Pharmacokinetics and Absolute Bioavailability of LCB01-0371.

Hyungsub Kim, Yong-Soon Cho, Hyeong-Seok Lim, 2019, Clinical therapeutics.

Pharmacokinetics, Pharmacodynamics, and Tolerability of Single-Dose Oral LCB01-0371, a Novel Oxazolidinone with Broad-Spectrum Activity, in Healthy Volunteers

Yong-Soon Cho, Hyeong-Seok Lim, K. Bae, 2018, Antimicrobial Agents and Chemotherapy.

Pharmacokinetic, pharmacodynamic, and safety/tolerability profiles of CG100649, a novel COX-2 inhibitor: results of a phase i, randomized, multiple-dose study in healthy Korean men and women.

Hyeong-Seok Lim, Yook-Hwan Noh, Mi Jo Kim, 2015, Clinical therapeutics.

The pharmacokinetics of letrozole: association with key body mass metrics.

Sang-Heon Cho, S. Choe, Hyeong-Seok Lim, 2012, International journal of clinical pharmacology and therapeutics.

DDDT_A_235802 3189..3199

Hyeong-Seok Lim, Yo Han Kim, H. Choi, 2020 .

Effect of Food on the Pharmacokinetics and Pharmacodynamics of a Single Oral Dose of Tegoprazan.

Hyeong-Seok Lim, Yo Han Kim, H. Choi, 2021, Clinical therapeutics.

Comparison of Pharmacodynamics between Tegoprazan and Dexlansoprazole Regarding Nocturnal Acid Breakthrough: A Randomized Crossover Study

Hyeong-Seok Lim, Yo Han Kim, H. Choi, 2022, Gut and Liver.

A prospective randomized trial comparing 5-fluorouracil (5-FU), mitomycin-C (MMC), and polysaccharide-K (PSK) versus UFT and PSK as adjuvant chemoimmunotherapy (CITX) for patients with locally advanced gastric cancer with curative resection

Seung-Yong Jeong, Jung-Hye Choi, Yunsuk Choi, 2007 .

Pharmacokinetic characteristics of bepotastine besilate in healthy subjects

K. Yu, Hyeong-Seok Lim, I. Jang, 2007 .

Assessment of Liver Function Using Pharmacokinetic Parameters of Gd-EOB-DTPA: Experimental Study in Rat Hepatectomy Model

J. Byun, K. Kim, Hyeong-Seok Lim, 2018, Contrast media & molecular imaging.

Trends of clinical trials from 2017 to 2019 in Korea: an integrated analysis based on the Ministry of Food and Drug Safety (MFDS) and the Clinical Research Information Service (CRIS) registries

Hyungsub Kim, K. Yu, Hyeong-Seok Lim, 2021, Translational and clinical pharmacology.

Modeling Approach with Therapeutic Drug Monitoring Data to Describe Time Course of Clozapine Exposure and Positive and Negative Syndrome Scale Scores

Sang-In Park, Hyeong-Seok Lim, Euitae Kim, 2022, Therapeutic drug monitoring.

Early Bactericidal Activity of Delpazolid (LCB01-0371) in Patients with Pulmonary Tuberculosis

T. Shim, S. H. Lee, J. Joh, 2021, Antimicrobial agents and chemotherapy.

Pharmacokinetic interaction between pitavastatin and valsartan: a randomized, open-labeled crossover study in healthy male Korean volunteers.

Hyeong-Seok Lim, Yook-Hwan Noh, Mi Jo Kim, 2012, Clinical therapeutics.

Quantitative Predictive Models for the Degree of Disability After Acute Ischemic Stroke

D. Kang, Hyeong-Seok Lim, S. M. Kim, 2018, Journal of clinical pharmacology.

A Population Pharmacokinetic Model of Intravenous Dexmedetomidine for Mechanically Ventilated Children after Neurosurgery

Jin‐Tae Kim, Hee‐Soo Kim, Eun-Hee Kim, 2019, Journal of clinical medicine.

Effects of ketoconazole on the pharmacokinetic properties of CG100649, a novel NSAID: a randomized, open-label crossover study in healthy Korean male volunteers.

Hyeong-Seok Lim, Yook-Hwan Noh, Seok-Joon Jin, 2014, Clinical therapeutics.

Population Pharmacokinetic and Pharmacodynamic Analysis of Polmacoxib in Healthy Volunteers and Patients With Osteoarthritis.

Yong-Soon Cho, Hyeong-Seok Lim, K. Bae, 2021, Clinical therapeutics.

Comparison of Pharmacokinetic Characteristics and Safety Between JW Amlodipine® Tablet 5 mg and Novarsc® Tablet 5 mg in Healthy Male Volunteers

Sang-Heon Cho, S. Choe, Hyeong-Seok Lim, 2013 .

A single-dose, crossover study comparing the pharmacokinetics and pharmacodynamics of 2 formulations of metformin in healthy volunteers.

Hyeong-Seok Lim, Yook-Hwan Noh, Seok-Joon Jin, 2012, International journal of clinical pharmacology and therapeutics.

Therapeutic dosage assessment based on population pharmacokinetics of a novel single-dose transdermal donepezil patch in healthy volunteers

Hyeong-Seok Lim, Yo Han Kim, H. Choi, 2015, European Journal of Clinical Pharmacology.

HAPLOTYPE STRUCTURE AND ALLELE FREQUENCIES OF CYP2B6 IN A KOREAN POPULATION

Joo-Youn Cho, K. Yu, Hyeong-Seok Lim, 2004, Drug Metabolism and Disposition.

Bioavailability and tolerability of combination treatment with revaprazan 200 mg + itopride 150 mg: a randomized crossover study in healthy male Korean volunteers.

Hyeong-Seok Lim, S. Jang, Yook-Hwan Noh, 2012, Clinical therapeutics.

Phase II study of S-1 combined with oxaliplatin as therapy for patients with metastatic biliary tract cancer: influence of the CYP2A6 polymorphism on pharmacokinetics and clinical activity

J. Shin, Hyeong-Seok Lim, M. Ryu, 2011, British Journal of Cancer.

Impact of CYP2D6, CYP3A5, CYP2C19, CYP2A6, SLCO1B1, ABCB1, and ABCG2 gene polymorphisms on the pharmacokinetics of simvastatin and simvastatin acid

Sang-Heon Cho, S. Choe, Hyeong-Seok Lim, 2015, Pharmacogenetics and genomics.

Assessment of the influence of severe renal impairment on the pharmacokinetics of mirodenafil in Korean male volunteers.

Sang-Heon Cho, S. Choe, Hyeong-Seok Lim, 2012, International journal of clinical pharmacology and therapeutics.

Pharmacokinetic interaction of telmisartan with s-amlodipine: an open-label, two-period crossover study in healthy Korean male volunteers.

Hyeong-Seok Lim, Yook-Hwan Noh, Seok-Joon Jin, 2012, Clinical therapeutics.

single dose pharmacokinetics of the novel transdermal donepezil patch in healthy volunteers

Hyeong-Seok Lim, Yo Han Kim, H. Choi, 2015 .

single dose pharmacokinetics of the novel transdermal donepezil patch in healthy volunteers

Hyeong-Seok Lim, Yo Han Kim, H. Choi, 2015 .

Exploration of Optimal Dosing Regimens of Haloperidol, a D2 Antagonist, via Modeling and Simulation Analysis in a D2 Receptor Occupancy Study

Hyeong-Seok Lim, I. Jang, Sang Eun Kim, 2013, Pharmaceutical Research.