I. Jang

Ji Won Lee, N. Kim, June-Dong Park, 2015, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Characterization of ADME gene variation in 21 populations by exome sequencing

A. S. Gross, G. Abecasis, M. Nelson, 2016, Pharmacogenetics and genomics.

Comparisons of the pharmacokinetics and tolerability of fixed-dose combinations of amlodipine besylate/losartan and amlodipine camsylate/losartan in healthy subjects: a randomized, open-label, single-dose, two-period, two-sequence crossover study

K. Yu, I. Jang, Sang-Min Cho, 2016, Drug design, development and therapy.

Verification of biomarkers for diabetic retinopathy by multiple reaction monitoring.

K. Park, Youngsoo Kim, I. Jang, 2010, Journal of proteome research.

Reduced exposure evaluation of an Electrically Heated Cigarette Smoking System. Part 4: Eight-day randomized clinical trial in Korea.

I. Jang, A. Tricker, R. Dempsey, 2012, Regulatory toxicology and pharmacology : RTP.

Frequency of CYP2C9 variant alleles, including CYP2C9*13 in a Korean population and effect on glimepiride pharmacokinetics

J. Shin, I. Jang, Y. Yoon, 2012, Journal of clinical pharmacy and therapeutics.

Pharmacokinetic Interaction of Fimasartan, a New Angiotensin II Receptor Antagonist, With Amlodipine in Healthy Volunteers

Joo-Youn Cho, K. Yu, I. Jang, 2011, Journal of cardiovascular pharmacology.

Favorable Outcome of Post-Transplantation Cyclophosphamide Haploidentical Peripheral Blood Stem Cell Transplantation with Targeted Busulfan-Based Myeloablative Conditioning Using Intensive Pharmacokinetic Monitoring in Pediatric Patients.

June-Dong Park, K. Yu, S. Song, 2018, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Effect of cytochrome P450 2C19 genetic polymorphism and coadministration with ketoconazole on the platelet aggregation response to clopidogrel in Korean healthy subjects

Joo-Youn Cho, K. Yu, Jung-Ryul Kim, 2009 .

Effects of HM30181, a P-glycoprotein inhibitor, on the pharmacokinetics and pharmacodynamics of loperamide in healthy volunteers.

Joo-Youn Cho, K. Yu, I. Jang, 2014, British journal of clinical pharmacology.

Comparison of the Plasma Metabolome Profiles Between the Internal Thoracic Artery and Ascending Aorta in Patients Undergoing Coronary Artery Bypass Graft Surgery Using Gas Chromatography Time-of-Flight Mass Spectrometry

A. Kim, Joo-Youn Cho, I. Jang, 2019, Journal of Korean medical science.

Pharmacokinetic Profiles of Ceftazidime after Intravenous Administration in Patients Undergoing Automated Peritoneal Dialysis

C. Ahn, K. Oh, Y. Hwang, 2011, Antimicrobial Agents and Chemotherapy.

Effect of Peritoneal Dialysis on Plasma and Peritoneal Fluid Concentrations of Isoniazid, Pyrazinamide, and Rifampin

C. Ahn, K. Oh, I. Jang, 2003, Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.

Safety, tolerability and pharmacokinetics of 21 day multiple oral administration of a new oxazolidinone antibiotic, LCB01-0371, in healthy male subjects

K. Yu, Jae-Yong Chung, I. Jang, 2018, The Journal of antimicrobial chemotherapy.

Safety , tolerability and pharmacokinetics of 21 day multiple oral administration of a new oxazolidinone antibiotic , LCB 01-0371 , in healthy male subjects

K. Yu, Jae-Yong Chung, I. Jang, 2017 .

Ursodeoxycholic acid exerts hepatoprotective effects by regulating amino acid, flavonoid, and fatty acid metabolic pathways

S. Ji, Joo-Youn Cho, K. Yu, 2019, Metabolomics.

Pharmacokinetic/Pharmacodynamic Interaction Between Evogliptin and Pioglitazone in Healthy Male Subjects

K. Yu, I. Jang, SeungHwan Lee, 2020, Drug design, development and therapy.

Pharmacokinetics, pharmacodynamics, and tolerability of the dipeptidyl peptidase IV inhibitor LC15-0444 in healthy Korean men: a dose-block-randomized, double-blind, placebo-controlled, ascending single-dose, Phase I study.

Joo-Youn Cho, K. Yu, Jung-Ryul Kim, 2008, Clinical therapeutics.

Pharmacokinetic/Pharmacodynamic Interactions Between Evogliptin and Glimepiride in Healthy Male Subjects

K. Yu, I. Jang, SeungHwan Lee, 2020, Drug design, development and therapy.

Absence of ethnic differences in the pharmacokinetics of moxifloxacin, simvastatin, and meloxicam among three East Asian populations and Caucasians

M. Takeuchi, Yoshiro Saito, M. Tohkin, 2016, British journal of clinical pharmacology.

Pharmacokinetic interaction of flecainide and paroxetine in relation to the CYP2D6*10 allele in healthy Korean subjects.

Joo-Youn Cho, K. Yu, I. Jang, 2008, British journal of clinical pharmacology.

Pharmacokinetic and Pharmacodynamic Interaction Between Gemigliptin and Metformin in Healthy Subjects

Y. Cho, Joo-Youn Cho, K. Yu, 2014, Clinical Drug Investigation.

Effects of Angelicae tenuissima radix, Angelicae dahuricae radix and Scutellariae radix extracts on cytochrome P450 activities in healthy volunteers.

Joo-Youn Cho, K. Yu, I. Jang, 2009, Basic & clinical pharmacology & toxicology.

Utility of a One‐Point (3‐Hour Postdose) Plasma Metabolic Ratio as a Phenotyping Test Using Metoprolol in Two East Asian Populations

K. Chiba, T. Ishizaki, I. Jang, 1992, Therapeutic drug monitoring.

Pharmacokinetic and Pharmacodynamic Comparison of Two Formulations of a Fixed-Dose Combination of Gemigliptin/Rosuvastatin 50/20 mg: A Randomized, Open-Label, Single-Dose, Two-Way Crossover Study

K. Yu, I. Jang, SeungHwan Lee, 2021, Drug design, development and therapy.

DDDT_A_288986 651..658

K. Yu, I. Jang, SeungHwan Lee, 2021 .

A Fixed-Dose Combination Of Gemigliptin And Rosuvastatin Exhibits Similar Pharmacokinetics, Pharmacodynamics, And Safety Compared To That Of A Loose Combination In Healthy Subjects

Eunwoo Kim, K. Yu, I. Jang, 2019, Drug design, development and therapy.

Effects of Pregnane X Receptor (NR1I2) and CYP2B6 Genetic Polymorphisms on the Induction of Bupropion Hydroxylation by Rifampin

Joo-Youn Cho, K. Yu, Jae-Yong Chung, 2011, Drug Metabolism and Disposition.

Prediction of Drug–Drug Interaction Potential of Tegoprazan Using Physiologically Based Pharmacokinetic Modeling and Simulation

I. Jang, SeungHwan Lee, Su-jin Rhee, 2021, Pharmaceutics.

Evaluation of Pharmacokinetics and Tolerability of Eplerenone after Multiple Oral Doses of 100 mg in Healthy Korean Volunteers

D. Oh, K. Yu, I. Jang, 2011 .

Oral absorption of voriconazole is affected by SLCO2B1 c.*396T>C genetic polymorphism in CYP2C19 poor metabolizers

Sang-In Park, A. Kim, S. Ji, 2020, The Pharmacogenomics Journal.

Electronic medical records-based comparison of glycemic control efficacy between sulfonylureas and dipeptidyl peptidase-4 inhibitors added on to metformin monotherapy in patients with type 2 diabetes

K. Yu, I. Jang, SeungHwan Lee, 2020, Translational and clinical pharmacology.

A pilot study to investigate the utility of NAT2 genotype-guided isoniazid monotherapy regimens in NAT2 slow acetylators.

Jihoon G. Yoon, Jihoon G Yoon, Joo-Youn Cho, 2020, Pharmacogenetics and genomics.

Changes in Cardiac Function After a Single Intravenous Administration of CKD-712 in Healthy Male Volunteers

Sang-In Park, K. Yu, I. Jang, 2017, Clinical Drug Investigation.

Sustained Increase in the Oral Bioavailability of Loperamide after a Single Oral Dose of HM30181, a P‐glycoprotein Inhibitor, in Healthy Male Participants

Joo-Youn Cho, K. Yu, Jae-Yong Chung, 2013, Basic & clinical pharmacology & toxicology.

Rapid Hepatobiliary Excretion of Micelle-Encapsulated/Radiolabeled Upconverting Nanoparticles as an Integrated Form

Taeghwan Hyeon, Dong Soo Lee, Yun-Sang Lee, 2015, Scientific Reports.

Pharmacokinetics of extended-release versus conventional tramadol/acetaminophen fixed-dose combination tablets: an open-label, 2-treatment, multiple-dose, randomized-sequence crossover study in healthy korean male volunteers.

Joo-Youn Cho, K. Yu, I. Jang, 2011, Clinical therapeutics.

Safety, pharmacokinetics and pharmacodynamics of BI 655064 in phase 1 clinical trials in healthy Chinese and Japanese subjects

C. Grimaldi, I. Jang, J. Steffgen, 2020, British journal of clinical pharmacology.

Functional characterization of MATE2-K genetic variants and their effects on metformin pharmacokinetics

S. Cho, E. Park, Joo-Youn Cho, 2013, Pharmacogenetics and genomics.

Pharmacokinetics and Tolerability Evaluation of Human Coagulation Recombinant Factor VIII (GreenGene^TM) in Hemophilia A Patients

Joo-Youn Cho, K. Yu, Jae-Yong Chung, 2011 .

The effect of udenafil on the hemodynamics of healthy male volunteers administered tamsulosin

Joo-Youn Cho, K. Yu, Jung-Ryul Kim, 2013, Current medical research and opinion.

Association between tumor necrosis factor alpha 308G/A polymorphism and increased proinflammatory cytokine release after cardiac surgery with cardiopulmonary bypass in the Korean population.

I. Jang, S. Yoon, Y. Lim, 2009, Journal of cardiothoracic and vascular anesthesia.

Ethnic differences and relationships in the oral pharmacokinetics of nifedipine and erythromycin

Joo-Youn Cho, K. Yu, S. Yi, 2001, Clinical pharmacology and therapeutics.

The effect of fimasartan, an angiotensin receptor type 1 blocker, on the pharmacokinetics and pharmacodynamics of warfarin in healthy Korean male volunteers: a one-sequence, two-period crossover clinical trial.

Joo-Youn Cho, K. Yu, I. Jang, 2012, Clinical therapeutics.

Pharmacokinetic and Pharmacodynamic Evaluation of a Novel Proton Pump Inhibitor, YH1885, in Healthy Volunteers

Joo-Youn Cho, K. Yu, Jae-Yong Chung, 2004, Journal of clinical pharmacology.

Pharmacokinetics of Hydroxychloroquine and Its Clinical Implications in Chemoprophylaxis against Malaria Caused by Plasmodium vivax

Jae-Won Park, Joo-Youn Cho, T. Klein, 2009, Antimicrobial Agents and Chemotherapy.

Pharmacokinetics and Tolerability Evaluation of Fudosteine after Oral Administration in Healthy Korean Volunteers

Joo-Youn Cho, K. Yu, Jae-Yong Chung, 2011 .

Tolerability and pharmacokinetics of a new P-glycoprotein inhibitor, HM30181, in healthy Korean male volunteers: single- and multiple-dose randomized, placebo-controlled studies.

Joo-Youn Cho, K. Yu, I. Jang, 2012, Clinical therapeutics.

Dose‐dependent glucosuria of DWP16001, a novel selective sodium–glucose cotransporter‐2 inhibitor, in healthy subjects

K. Yu, I. Jang, J. Hwang, 2022, British journal of clinical pharmacology.

Human immune response to a Pseudomonas aeruginosa outer membrane protein vaccine.

D. Yim, I. Jang, D. Ahn, 1999, Vaccine.

Pharmacokinetics and Pharmacodynamics of Oral Tolvaptan Administered in 15- to 60-mg Single Doses To Healthy Korean Men

Joo-Youn Cho, K. Yu, I. Jang, 2012, Journal of cardiovascular pharmacology.

Pharmacokinetic comparison between a fixed-dose combination of fimasartan/amlodipine/hydrochlorothiazide 60/10/25 mg and a corresponding loose combination of fimasartan/amlodipine 60/25 mg and hydrochlorothiazide 25 mg in healthy subjects

K. Yu, I. Jang, Donghwan Lee, 2021, Translational and clinical pharmacology.

Population Pharmacokinetics of Theophylline in Premature Korean Infants

Joo-Youn Cho, K. Yu, I. Jang, 2013, Therapeutic drug monitoring.

Population Pharmacokinetics of Vancomycin in Korean Pediatric Patients

K. Yu, Jung-Ryul Kim, I. Jang, 2008 .

Decreased acetylation of isoniazid in chronic renal failure

I. Jang, Jae-Gook Shin, Y. Cha, 1993, Clinical pharmacology and therapeutics.

ST2 blockade mitigates peritoneal fibrosis induced by TGF‐β and high glucose

K. Oh, Y. Kim, D. Kim, 2019, Journal of cellular and molecular medicine.

Dose-dependent reduction of lymphocyte count and heart rate after multiple administration of LC51-0255, a novel sphingosine-1-phosphate receptor 1 modulator, in healthy subjects

K. Yu, I. Jang, SeungHwan Lee, 2022, Frontiers in Pharmacology.

Pharmacokinetics of T-614 after Single Oral Administration in Healthy Korean Volunteers

K. Yu, Jung-Ryul Kim, I. Jang, 2013 .

Pharmacokinetic–Pharmacodynamic Modelling of Biomarker Response to Sitagliptin in Healthy Volunteers

Joo-Youn Cho, K. Yu, Jung-Ryul Kim, 2013, Basic & clinical pharmacology & toxicology.

Comparison of Pharmacokinetics and Safety Between Coadministration of Cilostazol and Ginkgo Biloba Extract and Administration of a Fixed-Dose Combination

K. Yu, I. Jang, K. Lim, 2010 .

Usefulness of saliva for perampanel therapeutic drug monitoring

K. Chu, Soon-Tae Lee, Manho Kim, 2020, Epilepsia.

K. Yu, I. Jang, Sang Won Lee, 2022 .

DDDT_A_303772 1735..1747

Joo-Youn Cho, K. Yu, I. Jang, 2021 .

The utility of CYP3A activity endogenous markers for evaluating drug-drug interaction between sildenafil and CYP3A inhibitors in healthy subjects.

Sumin Yoon, A. Kim, Yujin Lee, 2020, Drug metabolism and pharmacokinetics.

Quantitative prediction of hepatic CYP3A activity using endogenous markers in healthy subjects after administration of CYP3A inhibitors or inducers.

A. Kim, Joo-Youn Cho, K. Yu, 2019, Drug metabolism and pharmacokinetics.

Distribution of Exogenous and Endogenous CYP3A Markers and Related Factors in Healthy Males and Females

A. Kim, Joo-Youn Cho, K. Yu, 2017, The AAPS Journal.

A randomized, double-blind, single-dose, two-arm, parallel study comparing pharmacokinetics, immunogenicity and tolerability of branded adalimumab and its biosimilar LBAL in healthy male volunteers

Joo-Youn Cho, K. Yu, I. Jang, 2017, Expert opinion on investigational drugs.

Pharmacokinetic and Pharmacodynamic Properties of a New Long-Acting Granulocyte Colony-Stimulating Factor (HM10460A) in Healthy Volunteers

Joo-Youn Cho, K. Yu, I. Jang, 2013, BioDrugs.

Pharmacogenomic information from CPIC and DPWG guidelines and its application on drug labels

I. Jang, SeungHwan Lee, Soyoung Lee, 2020, Translational and clinical pharmacology.

Ursodeoxycholic acid improves liver function via phenylalanine/tyrosine pathway and microbiome remodelling in patients with liver dysfunction

Jinho Yang, Yoon-Keun Kim, S. Ji, 2018, Scientific Reports.

Efficacy, tolerability, and pharmacokinetics of oxcarbazepine oral loading in patients with epilepsy

K. Chu, Sang Kun Lee, Joo-Youn Cho, 2012, Epilepsia.

Updated safety and efficacy results from phase I/II study of HM61713 in patients (pts) with EGFR mutation positive non-small cell lung cancer (NSCLC) who failed previous EGFR-tyrosine kinase inhibitor (TKI).

Keunchil Park, E. Cho, Dong-Wan Kim, 2015 .

Relationship Between Absolute Neutrophil Count Profiles and Pharmacokinetics of DA-3031, a Pegylated Granulocyte Colony-Stimulating Factor (Pegylated-G-CSF): A Dose Block-Randomized, Double-Blind, Dose-Escalation Study in Healthy Subjects

Joo-Youn Cho, K. Yu, I. Jang, 2013, Clinical Drug Investigation.

Safety, tolerability and pharmacokinetics of udenafil, a novel PDE-5 inhibitor, in healthy young Korean subjects.

Joo-Youn Cho, K. Yu, Jae-Yong Chung, 2008, British journal of clinical pharmacology.

Quantification of Ticlopidine in Human Plasma Using Protein Precipitation and Liquid Chromatography Coupled with Tandem Mass Spectrometry

Joo-Youn Cho, K. Yu, I. Jang, 2011 .

An assessment of the pharmacokinetics, pharmacodynamics, and tolerability of GCPGC, a novel pegylated granulocyte colony-stimulating factor (G-CSF), in healthy subjects

K. Yu, I. Jang, K. Lim, 2014, Investigational new drugs.

Tolerability and Pharmacokinetics Following a Single Dose of Vardenafil in Healthy Korean Volunteers

K. Yu, Hyeong-Seok Lim, I. Jang, 2012 .

Time course of the changes in prednisolone pharmacokinetics after co-administration or discontinuation of rifampin

J. S. Lee, I. Jang, S. Shin, 2004, European Journal of Clinical Pharmacology.

Effect of the CYP2D6 genotype on the pharmacokinetics of tropisetron in healthy Korean subjects

D. Oh, B. Min, Joo-Youn Cho, 2003, European Journal of Clinical Pharmacology.

Novel nanocrystal formulation of megestrol acetate has improved bioavailability compared with the conventional micronized formulation in the fasting state

Joo-Youn Cho, K. Yu, I. Jang, 2014, Drug design, development and therapy.

Pharmacodynamic comparison of two formulations of Acarbose 100‐mg tablets

I. Jang, S. Byun, K. Yu, 2012, Journal of clinical pharmacy and therapeutics.

Evaluation of the pharmacokinetics, food effect, pharmacodynamics, and tolerability of DA-1229, a dipeptidyl peptidase IV inhibitor, in healthy volunteers: first-in-human study.

Joo-Youn Cho, K. Yu, I. Jang, 2012, Clinical therapeutics.

Safety, tolerability, pharmacokinetic, and pharmacodynamic characteristics of vutiglabridin: A first‐in‐class, first‐in‐human study

K. Yu, I. Jang, SeungHwan Lee, 2022, Clinical and translational science.

Pharmacokinetics, Pharmacodynamics and Safety of JES9501 after Single and Multiple Oral Administration in Healthy Subjects

Joo-Youn Cho, K. Yu, Jae-Yong Chung, 2013 .

Pharmacokinetics of Second-Line Antituberculosis Drugs after Multiple Administrations in Healthy Volunteers

Jong Sun Park, Sang-In Park, K. Yu, 2015, Antimicrobial Agents and Chemotherapy.

Taq1A polymorphism in the dopamine D2 receptor gene as a predictor of clinical response to aripiprazole

J. Kwon, D. Kang, Jung-Seok Choi, 2008, European Neuropsychopharmacology.

Does albumin preinfusion potentiate diuretic action of furosemide in patients with nephrotic syndrome?

C. Ahn, J. S. Lee, I. Jang, 2001, Journal of Korean medical science.

Removal of Amikacin in Patients Undergoing Continuous Venovenous Hemodiafiltration

K. Oh, Y. Kim, K. Yu, 2006 .

Hydrochlorothiazide does not increase furosemide's effects in end-stage renal disease

D. Yim, I. Jang, H. Oh, 2017, Translational and clinical pharmacology.

Lack of association between ABCB1, ABCG2, and ABCC2 genetic polymorphisms and multidrug resistance in partial epilepsy

S. I. Lee, K. Chu, Joo-Youn Cho, 2009, Epilepsy Research.

A post hoc analysis of intra-subject coefficients of variation in pharmacokinetic measures to calculate optimal sample sizes for bioequiva- lence studies

I. Jang, SeungHwan Lee, Jaeseong Oh, 2017 .

Validated LC-MS/MS Assay for the Quantitative Determination of Fimasartan in Human Plasma: Application to Pharmacokinetic Studies.

Joo-Youn Cho, K. Yu, I. Jang, 2015, Journal of chromatographic science.

Quantification of Human Plasma-Busulfan Concentration by Liquid Chromatography-Tandem Mass Spectrometry

Ji Won Lee, K. Yu, S. Song, 2013, Annals of laboratory medicine.

CYP1A2 activity as a risk factor for bladder cancer.

S. W. Lee, D. Yim, S. Oh, 1994, Journal of Korean medical science.

Assessment of induced CYP3A activity in pregnant women using 4β-hydroxycholesterol: Cholesterol ratio as an appropriate metabolic marker.

S. M. Lee, S. Kim, Joong-Shin Park, 2018, Drug metabolism and pharmacokinetics.

Pharmacokinetic and pharmacodynamic properties of the calcimimetic agent cinacalcet (KRN1493) in healthy male Korean subjects: a randomized, open-label, single ascending-dose, parallel-group study.

K. Yu, I. Jang, K. Lim, 2012, Clinical therapeutics.

Population Pharmacokinetic Analysis and Dosing Regimen Optimization of Aprotinin in Neonates and Young Infants Undergoing Cardiopulmonary Bypass

I. Jang, W. Kim, J. Kwak, 2011, Journal of clinical pharmacology.

Voriconazole-associated severe hyponatremia.

N. Kim, M. Oh, W. Park, 2012, Medical mycology.

Safety, Tolerability, and Serum/Tear Pharmacokinetics of Human Recombinant Epidermal Growth Factor Eyedrops in Healthy Subjects

K. Yu, I. Jang, J. Hyon, 2022, Pharmaceuticals.

Pharmacokinetics/Genotype Associations for Major Cytochrome P450 Enzymes in Native and First‐ and Third‐generation Japanese Populations: Comparison With Korean, Chinese, and Caucasian Populations

J. Paulauskis, K. Wilner, Y. Fujio, 2008, Clinical pharmacology and therapeutics.

Effect of ketoconazole on the pharmacokinetics of udenafil in healthy Korean subjects.

Joo-Youn Cho, K. Yu, I. Jang, 2010, British journal of clinical pharmacology.

Sensitive liquid chromatography assay with ultraviolet detection for a new phosphodiesterase V inhibitor, DA-8159, in human plasma and urine.

Joo-Youn Cho, K. Yu, Hyeong-Seok Lim, 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Comparison of the Pharmacokinetics Between Udenafil 100 mg tablets and 200 mg tablets in Healthy Volunteers

Joo-Youn Cho, K. Yu, I. Jang, 2008 .

Population pharmacokinetic analysis to recommend the optimal dose of udenafil in patients with mild and moderate hepatic impairment.

Jongtae Lee, Joo-Youn Cho, I. Jang, 2016, British journal of clinical pharmacology.

Single-dose Pharmacokinetics of Garenoxacin in Healthy Korean Volunteers

K. Yu, I. Jang, Tae-Eun Kim, 2010 .

Influence of Ginkgo biloba extract on the pharmacodynamic effects and pharmacokinetic properties of ticlopidine: an open-label, randomized, two-period, two-treatment, two-sequence, single-dose crossover study in healthy Korean male volunteers.

Joo-Youn Cho, K. Yu, Jung-Ryul Kim, 2010, Clinical therapeutics.

Successful Empirical Antifungal Therapy of Intravenous Itraconazole with Pharmacokinetic Evidence in Pediatric Cancer Patients Undergoing Hematopoietic Stem Cell Transplantation

Ji Won Lee, June-Dong Park, K. Yu, 2015, Clinical Drug Investigation.

An Improved UPLC Method for Rapid Analysis of Levofloxacin in Human Plasma

I. Jang, Y. Yoon, Woomi Kim, 2008 .

Population pharmacokinetic modelling of aripiprazole and its active metabolite, dehydroaripiprazole, in psychiatric patients.

J. Kwon, D. Kang, Y. Kim, 2008, British journal of clinical pharmacology.

Gastroprotective Action of Cochinchina Momordica Seed Extract Is Mediated by Activation of CGRP and Inhibition of cPLA2/5-LOX Pathway

Nayoung Kim, H. Jung, J. H. Park, 2009, Digestive Diseases and Sciences.

MRP2 haplotypes confer differential susceptibility to toxic liver injury

Min Goo Lee, Y. Suh, S. Ahn, 2007, Pharmacogenetics and genomics.

Reduced Valproic Acid Serum Concentrations Due to Drug Interactions With Carbapenem Antibiotics: Overview of 6 Cases

Joo-Youn Cho, K. Yu, I. Jang, 2012, Therapeutic drug monitoring.

A haplotype-based molecular analysis of CFTR mutations associated with respiratory and pancreatic diseases.

Min Goo Lee, Y. Suh, Joon Chang, 2003, Human molecular genetics.

HAPLOTYPE STRUCTURE AND ALLELE FREQUENCIES OF CYP2B6 IN A KOREAN POPULATION

Joo-Youn Cho, K. Yu, Hyeong-Seok Lim, 2004, Drug Metabolism and Disposition.

Comparative steady-state pharmacokinetic study of an extended-release formulation of itopride and its immediate-release reference formulation in healthy volunteers

Joo-Youn Cho, K. Yu, I. Jang, 2014, Drug design, development and therapy.

Predicting Brain Occupancy from Plasma Levels using PET: Superiority of Combining Pharmacokinetics with Pharmacodynamics while Modeling the Relationship

Jae Sung Lee, Jun Soo Kwon, Euitae Kim, 2012, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Challenges and insights of early oncology drug development in the Asia-Pacific region: introduction of phase I oncology clinical trial center and experience sharing for early clinical trials in Seoul National University Hospital, Korea.

Y. Bang, Dong-Wan Kim, S. Im, 2019, Chinese clinical oncology.

Factors influencing topiramate clearance in adult patients with epilepsy: A population pharmacokinetic analysis

Jongtae Lee, Sang Kun Lee, I. Jang, 2016, Seizure.

Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin.

E. Shin, Yeon‐Kyeong Yoo, Dae-Ho Lee, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

The Fas Signaling Pathway Is a Common Genetic Risk Factor for Severe Cutaneous Drug Adverse Reactions Across Diverse Drugs

Ai-Young Lee, K. Min, Heung-Woo Park, 2018, Allergy, asthma & immunology research.

GWAS identifies two susceptibility loci for lamotrigine-induced skin rash in patients with epilepsy

Min Goo Lee, J. Lee, I. Jang, 2015, Epilepsy Research.

An Accelerator Mass Spectrometry‐Enabled Microtracer Study to Evaluate the First‐Pass Effect on the Absorption of YH4808

S. Dueker, A. Kim, I. Jang, 2017, Clinical pharmacology and therapeutics.

Korean, Japanese, and Chinese populations featured similar genes encoding drug-metabolizing enzymes and transporters: a DMET Plus microarray assessment

Youngjo Lee, Y. Sugiyama, Joo-Youn Cho, 2014, Pharmacogenetics and genomics.

A Placebo-Controlled, Single and Multiple Dose Study to Investigate the Appropriate Parameters for Evaluation of Pharmacodynamic Equivalence of Voglibose in Healthy Korean Volunteers

Sang-Heon Cho, K. Yu, I. Jang, 2013 .

Clinical activity and safety of HM61713, an EGFR-mutant selective inhibitor, in advanced non-small cell lung cancer (NSCLC) patients (pts) with EGFR mutations who had received EGFR tyrosine kinase inhibitors (TKIs).

Keunchil Park, Dong-Wan Kim, Dae-Ho Lee, 2014 .

A safety, pharmacokinetic, pharmacogenomic and population pharmacokinetic analysis of the third‐generation EGFR TKI, olmutinib (HM61713), after single oral administration in healthy volunteers

K. Lee, I. Jang, Seonghae Yoon, 2019, Basic & clinical pharmacology & toxicology.

YC-1 induces S cell cycle arrest and apoptosis by activating checkpoint kinases.

Jinho Kim, I. Jang, Jong-Wan Park, 2006, Cancer research.

Effect of OATP1B1 (SLCO1B1) variant alleles on the pharmacokinetics of pitavastatin in healthy volunteers

D. Oh, Joo-Youn Cho, K. Yu, 2005, Clinical pharmacology and therapeutics.

Therapeutic evaluation of sustained-releasing praziquantel (SRP) for clonorchiasis: phase 1 and 2 clinical studies.

Sung-Tae Hong, J. Chun, I. Jang, 2006, The Korean journal of parasitology.

A bioequivalence study of two levofloxacin tablets in healthy male subjects

S. Yim, I. Jang, Howard Lee, 2014 .

A bioequivalence study of two levofloxacin tab- lets in healthy male subjects

S. Yim, I. Jang, Seonghae Yoon, 2014 .

Trough Concentration Over 12.1 mg/L is a Major Risk Factor of Vancomycin-Related Nephrotoxicity in Patients With Therapeutic Drug Monitoring

Ju Han Kim, Sang-Heon Cho, Hye‐Ryun Kang, 2014, Therapeutic drug monitoring.

Optimal dose of intravenous pantoprazole in patients with peptic ulcer bleeding requiring endoscopic hemostasis in Korea

Nayoung Kim, H. Jung, K. Choi, 2009, Journal of gastroenterology and hepatology.

Night‐time gastric acid suppression by tegoprazan compared to vonoprazan or esomeprazole

K. Yu, I. Jang, Bongtae Kim, 2022, British journal of clinical pharmacology.

Safety, tolerability, pharmacodynamics and pharmacokinetics of DWP14012, a novel potassium‐competitive acid blocker, in healthy male subjects

S. Ji, I. Jang, J. Sunwoo, 2018, Alimentary pharmacology & therapeutics.

A novel K+ competitive acid blocker, YH4808, sustains inhibition of gastric acid secretion with a faster onset than esomeprazole: randomised clinical study in healthy volunteers

S. Yoon, Sumin Yoon, S. Yi, 2017, Alimentary pharmacology & therapeutics.

Pharmacodynamics of tegoprazan and revaprazan after single and multiple oral doses in healthy subjects

S. Ji, K. Yu, I. Jang, 2020, Alimentary pharmacology & therapeutics.

Comparative Pharmacokinetics/Pharmacodynamics of Clopidogrel Besylate and Clopidogrel Bisulfate in Healthy Korean Subjects

Joo-Youn Cho, K. Yu, Jung-Ryul Kim, 2012, Clinical Drug Investigation.

Population pharmacokinetics of artesunate and dihydroartemisinin following single- and multiple-dosing of oral artesunate in healthy subjects

Beesan Tan, Lee E Kirsch, H. Naik, 2009, Malaria Journal.

Influence of midazolam-related genetic polymorphism on conscious sedation during upper gastrointestinal endoscopy in a Korean population

J. Park, I. Jang, Hyun Kang, 2019, Scientific Reports.

Simultaneous LC–MS–MS Determination of HM30181A, [2-(2-{4-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-phenyl}-2H-tetrazol-5-yl)-4,5-dimethoxyphenyl]amide, as a new P-Glycoprotein Inhibitor and Its Two Metabolites, M1 and M2, in Human Plasma: Application to a Pharmacokinetic Study

Y. Choi, Joo-Youn Cho, K. Yu, 2011 .

Korean Variant Archive (KOVA): a reference database of genetic variations in the Korean population

R. Bjornson, W. Park, Murim Choi, 2017, Scientific Reports.

Safety, tolerability, and anti-tumor activity of olmutinib in non-small cell lung cancer with T790M mutation: A single arm, open label, phase 1/2 trial.

Keunchil Park, E. Cho, Dong-Wan Kim, 2019, Lung cancer.

Comparison of R(+)-α-lipoic acid exposure after R(+)-α-lipoic acid 200 mg and 300 mg and thioctic acid 600 mg in healthy Korean male subjects

K. Yu, I. Jang, S. Yoon, 2016 .

Targeted busulfan and fludarabine-based conditioning for bone marrow transplantation in chronic granulomatous disease

Ji Won Lee, June-Dong Park, K. Yu, 2016, Korean journal of pediatrics.

Pharmacokinetics of Fludarabine in Pediatric Hematopoietic Stem Cell Transplantation

Ji Won Lee, K. Yu, I. Jang, 2014 .

Changes in the gut microbiome influence the hypoglycemic effect of metformin through the altered metabolism of branched-chain and nonessential amino acids.

Eunwoo Kim, Yujin Lee, Joo-Youn Cho, 2021, Diabetes research and clinical practice.

Highly variable pharmacokinetics of once-daily intravenous busulfan when combined with fludarabine in pediatric patients: phase I clinical study for determination of optimal once-daily busulfan dose using pharmacokinetic modeling.

Ji Won Lee, N. Kim, K. Yu, 2012, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

14th Congress of the European Association for Clinical Pharmacology and Therapeutics (EACPT)

S. Misaka, I. Jang, F. Bengtsson, 2019, European Journal of Clinical Pharmacology.

Effects of DRD2 and CYP2D6 genotypes on delta EEG power response to aripiprazole in healthy male volunteers: a preliminary study

Jun Soo Kwon, Euitae Kim, Young Youn Kim, 2006, Human psychopharmacology.

Comparative Pharmacokinetics/Pharmacodynamics of Fixed-Dose Combination of Esomeprazole and Calcium Carbonate (AD-206) to the Conventional Esomeprazole

K. Yu, I. Jang, SeungHwan Lee, 2021, Drug design, development and therapy.

DDDT_A_341271 5099..5108

K. Yu, I. Jang, SeungHwan Lee, 2021 .

Pharmacokinetics of the evogliptin/metformin extended-release (5/1,000 mg) fixed-dose combination formulation compared to the corresponding loose combination, and food effect in healthy subjects

Joo-Youn Cho, K. Yu, I. Jang, 2016, Drug design, development and therapy.

Pharmacokinetics and pharmacodynamics of LC15-0444, a novel dipeptidyl peptidase IV inhibitor, after multiple dosing in healthy volunteers.

Joo-Youn Cho, K. Yu, Jung-Ryul Kim, 2009, British journal of clinical pharmacology.

Increased risk of atherothrombotic events associated with cytochrome P450 3A5 polymorphism in patients taking clopidogrel

J. Suh, K. Park, Hyo‐Soo Kim, 2006, Canadian Medical Association Journal.

Association of 5-HT 3A receptor Pro16Ser polymorphism with the incidence of PONV and the response to ondansetron in Korean patients

E. Song, I. Jang, Y. Jeon, 2008 .

Clinical implications of CYP2D6 genotypes predictive of tamoxifen pharmacokinetics in metastatic breast cancer.

Hyeong-Seok Lim, I. Jang, J. Ro, 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

ABCB1 polymorphism as prognostic factor in breast cancer patients treated with docetaxel and doxorubicin neoadjuvant chemotherapy

W. Han, D. Noh, S. Im, 2014, Cancer science.

Genetic Polymorphisms of eNOS, Hormone Receptor Status, and Survival of Breast Cancer

W. Han, D. Noh, R. Hayes, 2006, Breast Cancer Research and Treatment.

Effect of Erythrocyte Thiopurine Methyltransferase (TPMT) Activity on Azathioprine Immunosuppression Therapy in Renal Transplant Recipients

C. Ahn, J. Ha, Joo-Youn Cho, 2000 .

Identification of ω‐ or (ω‐1)‐Hydroxylated Medium‐Chain Acylcarnitines as Novel Urinary Biomarkers for CYP3A Activity

Joo-Youn Cho, K. Yu, I. Jang, 2018, Clinical pharmacology and therapeutics.

Pharmacokinetics and safety of cenobamate, a novel antiseizure medication, in healthy Japanese, and an ethnic comparison with healthy non‐Japanese

K. Yu, I. Jang, SeungHwan Lee, 2021, Clinical and translational science.

Targeted Next‐Generation Sequencing for Comprehensive Genetic Profiling of Pharmacogenes

Joo-Youn Cho, I. Jang, J. Cho, 2017, Clinical pharmacology and therapeutics.

Pharmacokinetics and Tolerance of the Phage Endolysin-Based Candidate Drug SAL200 after a Single Intravenous Administration among Healthy Volunteers

M. Seong, Joo-Youn Cho, K. Yu, 2017, Antimicrobial Agents and Chemotherapy.

Erythrocyte thiopurine methyltransferase activity in a Korean population.

H. Koo, D. Yim, I. Jang, 1996, British journal of clinical pharmacology.

A Population Pharmacokinetic Analysis of Fimasartan, a Selective Angiotensin II Receptor Antagonist, in Healthy Caucasian Subjects and Korean Patients With Hypertension

B. Oh, K. Yu, I. Jang, 2013, Clinical pharmacology in drug development.

Association of Tissue Factor Polymorphism with Fibrinolysis and Excessive Bleeding after Open Heart Surgery - A preliminary report -

I. Jang, S. Yoon, Y. Lim, 2007 .

Tolerability and single dose pharmacokinetics of a new PDE5 inhibitor, DA‐8159 in healthy male subjects

S. Yi, I. Jang, K. Hong, 2003 .

Angiotensin II type 1 receptor 1166A/C polymorphism in association with blood pressure response to exogenous angiotensin II

Hyeong-Seok Lim, Kyun-Seop Bae, Sang-Goo Shin, 2006, European Journal of Clinical Pharmacology.

Pharmacodynamics, Pharmacokinetics, and Tolerability of Intravenous or Subcutaneous GC1113, a Novel Erythropoiesis-Stimulating Agent

Jongtae Lee, Joo-Youn Cho, K. Yu, 2014, Clinical Drug Investigation.

Simple and sensitive determination of the new antitumor drug CKD-602 in human plasma by liquid chromatography.

Joo-Youn Cho, K. Yu, S. Yi, 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

The use of healthy volunteers instead of patients to inform drug dosing studies: a [11C]raclopride PET study

F. Turkheimer, S. Kapur, J. Kwon, 2011, Psychopharmacology.

Assessment of the effect of mirodenafil on the hemodynamics of healthy male Korean volunteers administered tamsulosin: a randomized, double-blind, placebo-controlled, 2-period crossover study.

K. Yu, I. Jang, K. Lim, 2012, Clinical therapeutics.

Pharmacometabolomics for predicting variable busulfan exposure in paediatric haematopoietic stem cell transplantation patients

Ji Won Lee, Joo-Youn Cho, K. Yu, 2017, Scientific Reports.

Taq1A polymorphism in the dopamine D2 receptor gene predicts brain metabolic response to aripiprazole in healthy male volunteers

J. Kwon, H. Jo, Jong-Min Lee, 2008, Pharmacogenetics and genomics.

Impact of Vancomycin‐Induced Changes in the Intestinal Microbiota on the Pharmacokinetics of Simvastatin

A. Kim, S. Ji, Joo-Youn Cho, 2020, Clinical and translational science.

Pharmacokinetics and Tolerability of Naftopidil after a Single Oral Administration in Healthy Korean Volunteers

K. Yu, I. Jang, SeungHwan Lee, 2010 .

Unraveling the Genomic Architecture of the CYP3A Locus and ADME Genes for Personalized Tacrolimus Dosing

Min Goo Lee, Y. J. Kim, Jihoon G. Yoon, 2021, Transplantation.

Assessment of the Drug–Drug Interactions Between Fimasartan and Hydrochlorothiazide in Healthy Volunteers

Joo-Youn Cho, K. Yu, I. Jang, 2012, Journal of cardiovascular pharmacology.

Pharmacokinetic and Pharmacodynamic Properties of a New Long-Acting Granulocyte Colony-Stimulating Factor (HM10460A) in Healthy Volunteers

Joo-Youn Cho, K. Yu, I. Jang, 2013, BioDrugs.

A thorough QT study to evaluate the QTc prolongation potential of two neuropsychiatric drugs, quetiapine and escitalopram, in healthy volunteers

Joo-Youn Cho, K. Yu, I. Jang, 2016, International clinical psychopharmacology.

Pharmacokinetics, pharmacodynamics, and tolerability of LC350189, a novel xanthine oxidase inhibitor, in healthy subjects

K. Yu, I. Jang, Howard Lee, 2015, Drug design, development and therapy.

Incidence of S‐mephenytoin hydroxylation deficiency in a Korean population and the interphenotypic differences in diazepam pharmacokinetics

K. Chiba, T. Ishizaki, I. Jang, 1992, Clinical pharmacology and therapeutics.

Urinary 6β-Hydroxycortisol/Cortisol Ratio Most Highly Correlates With Midazolam Clearance Under Hepatic CYP3A Inhibition and Induction in Females: A Pharmacometabolomics Approach

Joo-Youn Cho, K. Yu, I. Jang, 2016, AAPS Journal.

GC-MS–Based Quantitative Signatures of Cytochrome P450–Mediated Steroid Oxidation Induced by Rifampicin

Jeongae Lee, Joo-Youn Cho, I. Jang, 2013, Therapeutic drug monitoring.

Influence of Simvastatin on Pharmacokinetics/Pharmacodynamics of Aspirin after Oral Co-administration in Healthy Volunteers

D. Yim, K. Yu, I. Jang, 2011 .

The necessary conduct: Exploratory multiregional clinical trials in East Asia

K. Yu, I. Jang, Inseung Jeon, 2021, Clinical and translational science.

BI 1482694 (HM61713), an EGFR mutant-specific inhibitor, in T790M+ NSCLC: Efficacy and safety at the RP2D.

Keunchil Park, E. Cho, Dong-Wan Kim, 2016 .

Comparative Pharmacokinetics of HD203, a Biosimilar of Etanercept, with Marketed Etanercept (Enbrel ®)

Joo-Youn Cho, K. Yu, I. Jang, 2012, BioDrugs.

Aspirin Decreases Systemic Exposure to Clopidogrel Through Modulation of P‐Glycoprotein But Does Not Alter Its Antithrombotic Activity

K. Chu, S. Yoon, S. Ji, 2014, Clinical pharmacology and therapeutics.

Pharmacokinetic and pharmacodynamic comparison of two recombinant human erythropoietin formulations after single subcutaneous administration: an open-label, sequence-randomized, two-treatment crossover study in healthy Korean male volunteers.

K. Yu, I. Jang, Tae-Eun Kim, 2010, Clinical therapeutics.

A phase I study to evaluate the safety, tolerability, pharmacodynamic and pharmacokinetic profiles of ocular GLH8NDE in healthy male adults

K. Park, Jaehwi Lee, Ahnul Ha, 2021, Clinical and translational science.

Pharmacokinetic equivalence of CT‐P17 to high‐concentration (100 mg/ml) reference adalimumab: A randomized phase I study in healthy subjects

D. Furst, K. Yu, Hyeong-Seok Lim, 2021, Clinical and translational science.

Pharmacodynamic (hemodynamic) and pharmacokinetic comparisons of S-amlodipine gentisate and racemate amlodipine besylate in healthy Korean male volunteers: two double-blind, randomized, two-period, two-treatment, two-sequence, double-dummy, single-dose crossover studies.

K. Yu, Jung-Ryul Kim, I. Jang, 2010, Clinical therapeutics.

Effect of renal function on the pharmacokinetics of fimasartan: a single-dose, open-label, Phase I study

Jongtae Lee, Y. Kim, K. Yu, 2014, Drug design, development and therapy.

Comprehensive Metabolomic Search for Biomarkers to Differentiate Early Stage Hepatocellular Carcinoma from Cirrhosis

T. Park, E. Cho, Joo-Youn Cho, 2019, Cancers.

Pharmacokinetic and pharmacodynamic interaction between DWP16001, an sodium–glucose cotransporter 2 inhibitor and metformin in healthy subjects

K. Yu, I. Jang, J. Hwang, 2022, British journal of clinical pharmacology.

Pharmacokinetics and Safety of Extended-release Ranolazine in Korean and White Healthy Subjects

Joo-Youn Cho, K. Yu, I. Jang, 2022, Clinical Therapeutics.

Pharmacokinetics of Ginsenoside Compound K From a Compound K Fermentation Product, CK‐30, and From Red Ginseng Extract in Healthy Korean Subjects

K. Yu, I. Jang, SeungHwan Lee, 2021, Clinical pharmacology in drug development.

Comparative pharmacokinetics and tolerability of branded etanercept (25 mg) and its biosimilar (25 mg): a randomized, open-label, single-dose, two-sequence, crossover study in healthy Korean male volunteers.

K. Yu, I. Jang, Tae-Eun Kim, 2011, Clinical therapeutics.

Temporal changes and reversibility of carbamylated hemoglobin in renal failure.

C. Ahn, J. S. Lee, I. Jang, 1997, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Multiple-dose pharmacokinetics and pharmacodynamics of evogliptin (DA-1229), a novel dipeptidyl peptidase IV inhibitor, in healthy volunteers

Sang-Heon Cho, Joo-Youn Cho, K. Yu, 2014, Drug design, development and therapy.

Pharmacokinetics, Safety, and Tolerability of Tedizolid Phosphate After Single-dose Administration in Healthy Korean Male Subjects.

K. Yu, I. Jang, Howard Lee, 2017, Clinical therapeutics.

The novel carboxylesterase 1 variant c.662A>G may decrease the bioactivation of oseltamivir in humans

Joo-Youn Cho, K. Yu, I. Jang, 2017, PloS one.

Pharmacokinetics, Safety and Tolerability of DA-6034, an Anti-Inflammatory Agent, After Single and Multiple Oral Administrations in Healthy Volunteers

Jung-Ryul Kim, I. Jang, K. Lim, 2013, Clinical Drug Investigation.

The Serum Levels and Side Effects of Single Oral Loading of Controlled-Release Carbamazepine

S. Park, H. Bae, I. Jang, 2000 .

Pharmacokinetics and pharmacodynamics of intravenous dexmedetomidine in healthy Korean subjects

I. Jang, W. Wisemandle, K. Lim, 2012, Journal of clinical pharmacy and therapeutics.

Effect of rifampin on the plasma concentration and the clinical effect of haloperidol concomitantly administered to schizophrenic patients.

J. Woo, I. Jang, Jae-Gook Shin, 1996, Journal of clinical psychopharmacology.

Effect of omeprazole on the pharmacokinetics of moclobemide according to the genetic polymorphism of CYP2C19

D. Yim, Joo-Youn Cho, S. Yi, 2001, Clinical pharmacology and therapeutics.

Omeprazole hydroxylation is inhibited by a single dose of moclobemide in homozygotic EM genotype for CYP2C19.

D. Yim, Joo-Youn Cho, K. Yu, 2002, British journal of clinical pharmacology.

Safety, tolerability, pharmacokinetic/pharmacodynamic characteristics of bersiporocin, a novel prolyl‐tRNA synthetase inhibitor, in healthy subjects

K. Yu, I. Jang, Jaeseong Oh, 2023, Clinical and translational science.

Evaluation of drug prescribing patterns and therapeutic drug monitoring practice using electronic medical records

I. Jang, Seonghae Yoon, Sangmi Lee, 2022, Scientific reports.

The relationship between antipsychotic D2 occupancy and change in frontal metabolism and working memory

Jae Kyeong Jeong, F. Turkheimer, S. Kapur, 2012, Psychopharmacology.

Endogenous metabolic markers for predicting the activity of dihydropyrimidine dehydrogenase

Jihyun Kang, A. Kim, Joo-Youn Cho, 2021, Clinical and translational science.

Pharmacokinetic and Pharmacodynamic Characteristics of Tripegfilgrastim, a Pegylated G‐CSF, in Pediatric Patients with Solid Tumors

Joo-Youn Cho, K. Yu, I. Jang, 2021, Clinical pharmacology and therapeutics.

Pharmacokinetic Interaction Among Ezetimibe, Rosuvastatin, and Telmisartan

I. Jang, SeungHwan Lee, Sang Won Lee, 2021, Clinical pharmacology in drug development.

Tolerability and pharmacokinetics of lobeglitazone (CKD-501), a peroxisome proliferator-activated receptor-γ agonist: a single- and multiple-dose, double-blind, randomized control study in healthy male Korean subjects.

Joo-Youn Cho, K. Yu, Jung-Ryul Kim, 2011, Clinical therapeutics.

A Comparison of the Pharmacokinetics and Safety of Dapagliflozin Formate, an Ester Prodrug of Dapagliflozin, to Dapagliflozin Propanediol Monohydrate in Healthy Subjects

I. Jang, Sangmi Lee, Siyoung Sung, 2023, Drug design, development and therapy.

Effect of UGT2B7 Genotype on Pharmacokinetics of Valproate in Human Healthy Subjects

Joo-Youn Cho, K. Yu, Jung-Ryul Kim, 2004 .

Comparative pharmacokinetic evaluation of two formulations of bicalutamide 50-mg tablets: an open-label, randomized-sequence, single-dose, two-period crossover study in healthy Korean male volunteers.

K. Yu, I. Jang, S. Yoon, 2009, Clinical therapeutics.

Effect of multiple doses of fimasartan, an angiotensin II receptor antagonist, on the steady-state pharmacokinetics of digoxin in healthy volunteers.

S. Yoon, I. Jang, J. Cho, 2011, International journal of clinical pharmacology and therapeutics.

The Effect of the Newly Developed Angiotensin Receptor II Antagonist Fimasartan on the Pharmacokinetics of Atorvastatin in Relation to OATP1B1 in Healthy Male Volunteers

Min Goo Lee, Joo-Youn Cho, K. Yu, 2011, Journal of cardiovascular pharmacology.

Effects of perampanel on cognition and quantitative electroencephalography in patients with epilepsy

Kwang Su Cha, K. Chu, J. Sunwoo, 2020, Epilepsy & Behavior.

Pharmacokinetic study of single and multiple oral administrations of 2 mg dienogest in healthy Korean women.

Joong-Shin Park, K. Yu, I. Jang, 2013, Contraception.

Pharmacokinetics and tolerability of DA-8031, a novel selective serotonin reuptake inhibitor for premature ejaculation in healthy male subjects

Joo-Youn Cho, K. Yu, I. Jang, 2017, Drug design, development and therapy.

Effect of meal timing on pharmacokinetics and pharmacodynamics of tegoprazan in healthy male volunteers

I. Jang, SeungHwan Lee, J. Sunwoo, 2020, Clinical and translational science.

Effect of food on the pharmacokinetics of YH4808, a potassium-competitive acid blocker, after single- and multiple-oral dosing in healthy subjects

Eunwoo Kim, Joo-Youn Cho, K. Yu, 2018, European Journal of Clinical Pharmacology.

Assessment of Hepatic Cytochrome P450 3A Activity Using Metabolic Markers in Patients with Renal Impairment

Sumin Yoon, A. Kim, Yujin Lee, 2018, Journal of Korean medical science.

Comparative pharmacokinetics between two tablets of tramadol 37.5 mg/acetaminophen 325 mg and one tablet of tramadol 75 mg/acetaminophen 650 mg for extended-release fixed-dose combination

I. Jang, SeungHwan Lee, JaeWoo Kim, 2022, Translational and clinical pharmacology.

Effect of haemodialysis on the pharmacokinetics and pharmacodynamics of evogliptin

K. Oh, Y. Kim, Joo-Youn Cho, 2023, Diabetes, obesity & metabolism.

Pharmacokinetic and pharmacodynamic interaction of DWP16001, a sodium–glucose cotransporter 2 inhibitor, with gemigliptin and metformin in healthy adults

I. Jang, Sae Im Jeong, J. Hwang, 2022, British journal of clinical pharmacology.

Potential interactions between cilostazol and probucol: a two-part, single-dose, open-label study in healthy Korean male volunteers.

K. Yu, I. Jang, K. Lim, 2009, Clinical therapeutics.

Pharmacokinetic properties and effects of PT302 after repeated oral glucose loading tests in a dose-escalating study.

Sang-Heon Cho, K. Yu, I. Jang, 2014, Clinical therapeutics.

A positron emission tomography microdosing study with sertraline in healthy volunteers.

Jae Sung Lee, Yun-Sang Lee, Kwang-Hee Shin, 2012, International journal of clinical pharmacology and therapeutics.

Colorectal cancer diagnostic model utilizing metagenomic and metabolomic data of stool microbial extracellular vesicles

Young Soo Park, Jinho Yang, Y. Park, 2020, Scientific Reports.

Population pharmacokinetics and dose-response relationship of levetiracetam in adult patients with epilepsy

K. Chu, Soon-Tae Lee, K. Jung, 2017, Epilepsy Research.

Pharmacokinetic characteristics of bepotastine besilate in healthy subjects

K. Yu, Hyeong-Seok Lim, I. Jang, 2007 .

Investigation of bioequivalence of a new fixed‐dose combination of acarbose and metformin with the corresponding loose combination as well as the drug–drug interaction potential between both drugs in healthy adult male subjects

E. Brendel, Y. Liu, I. Jang, 2014, Journal of clinical pharmacy and therapeutics.

An analysis of QTc prolongation with atypical antipsychotic medications and selective serotonin reuptake inhibitors using a large ECG record database

Sang-In Park, K. Yu, I. Jang, 2016, Expert opinion on drug safety.

Evaluation of CYP2C19-Mediated Pharmacokinetic Drug Interaction of Tegoprazan, Compared with Vonoprazan or Esomeprazole

S. Ji, I. Jang, SeungHwan Lee, 2023, Clinical Pharmacokinetics.

Pharmacokinetics and tolerability of MB12066, a beta-lapachone derivative targeting NAD(P)H: quinone oxidoreductase 1: two independent, double-blind, placebo-controlled, combined single and multiple ascending dose first-in-human clinical trials

Joo-Youn Cho, K. Yu, I. Jang, 2017, Drug design, development and therapy.

Pharmacokinetics and tolerability of MB 12066 , a beta-lapachone derivative targeting naD ( P ) h : quinone oxidoreductase 1 : two independent , double-blind , placebo-controlled , combined single and multiple ascending dose first-inhuman clinical trials

Joo-Youn Cho, K. Yu, I. Jang, 2017 .

The pharmacokinetic, safety, and tolerability profiles of eslicarbazepine acetate are comparable between Korean and White subjects

Eunwoo Kim, Joo-Youn Cho, I. Jang, 2022, Clinical and translational science.

An open-label, single-dose, parallel-group, dose-increasing study comparing the pharmacokinetics and tolerability of pilsicainide hydrochloride in healthy Korean and Japanese male subjects.

K. Yu, Jung-Ryul Kim, I. Jang, 2009, Clinical therapeutics.

Phase I Study of CKD-516, a Novel Vascular Disrupting Agent, in Patients with Advanced Solid Tumors

Y. Bang, Keun-Wook Lee, I. Jang, 2015, Cancer research and treatment : official journal of Korean Cancer Association.

Pharmacokinetic properties and tolerability of rotigotine transdermal patch after repeated-dose application in healthy korean volunteers.

K. Yu, Jung-Ryul Kim, I. Jang, 2015, Clinical therapeutics.

Colorectal cancer diagnostic model utilizing metagenomic and metabolomic data of stool microbial extracellular vesicles

Y. Park, Jinho Yang, Yoon-Keun Kim, 2020, Scientific Reports.

Apple juice greatly reduces systemic exposure to atenolol.

K. Ohashi, Joo-Youn Cho, K. Yu, 2013, British journal of clinical pharmacology.

Calculating Occupancy when One does not have Baseline: A Comparison of Different Options

S. Kapur, J. Kwon, O. Howes, 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Distribution of Exogenous and Endogenous CYP3A Markers and Related Factors in Healthy Males and Females

A. Kim, Joo-Youn Cho, K. Yu, 2017, The AAPS Journal.

A pharmacokinetic comparison of two voriconazole formulations and the effect of CYP2C19 polymorphism on their pharmacokinetic profiles

Joo-Youn Cho, K. Yu, I. Jang, 2015, Drug design, development and therapy.

Pharmacometabolomics for predicting variable busulfan exposure in paediatric haematopoietic stem cell transplantation patients

Ji Won Lee, Joo-Youn Cho, K. Yu, 2017, Scientific Reports.

Effects of Proton Pump Inhibitors on Metformin Pharmacokinetics and Pharmacodynamics

Joo-Youn Cho, K. Yu, I. Jang, 2014, Drug Metabolism and Disposition.

A Phase 1 Study To Evaluate Safety and Pharmacokinetics following Administration of Single and Multiple Doses of the Antistaphylococcal Lysin LSVT-1701 in Healthy Adult Subjects

I. Jang, J. Hwang, S. Jun, 2022, Antimicrobial agents and chemotherapy.

Author Correction: Ursodeoxycholic acid improves liver function via phenylalanine/tyrosine pathway and microbiome remodelling in patients with liver dysfunction

Jinho Yang, Yoon-Keun Kim, S. Ji, 2018, Scientific Reports.

Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform

Joo-Youn Cho, K. Yu, I. Jang, 2021, Translational and clinical pharmacology.

Identification of influence of CYP3A5 genetic polymorphism in tacrolimus pharmacokinetics assessed from routine TDM data using population pharmacokinetic approach

S. Yi, I. Jang, K. Hong, 2003 .

Influence of OATP1B1 and BCRP polymorphisms on the pharmacokinetics and pharmacodynamics of rosuvastatin in elderly and young Korean subjects

Joo-Youn Cho, K. Yu, I. Jang, 2019, Scientific Reports.

Multiple-dose pharmacokinetics of fesoterodine sustained-release in healthy Korean volunteers.

Joo-Youn Cho, K. Yu, I. Jang, 2012, International journal of clinical pharmacology and therapeutics.

No associations between 5-HTT, 5-HT2A gene polymorphisms and obsessive-compulsive disorder in a Korean population

J. Kwon, S. Yoo, Joo-Youn Cho, 2006 .

Pharmacokinetic characteristics of fluticasone, salmeterol and tiotropium after concurrent inhalation

I. Jang, SeungHwan Lee, J. Sunwoo, 2017, Translational and clinical pharmacology.

Assessment of the relationship between plasma nortriptyline concentration and inhibition of salivation: Single-dose study

J. Woo, I. Jang, S. Shin, 1991 .

Immunogenicity and safety of a single intramuscular dose of a diphtheria-tetanus toxoid (Td) vaccine (GC1107) in Korean adults.

W. Park, Joo-Youn Cho, K. Yu, 2011, Vaccine.

The safety, tolerability and pharmacokinetics of BI 409306, a novel and potent PDE9 inhibitor: Overview of three Phase I randomised trials in healthy volunteers

M. Sand, I. Jang, Viktoria Moschetti, 2018, European Neuropsychopharmacology.

Effect of CYP2C19 Polymorphism on the Pharmacokinetics of Voriconazole After Single and Multiple Doses in Healthy Volunteers

Joo-Youn Cho, K. Yu, I. Jang, 2012, Journal of clinical pharmacology.

Assessment of Appropriateness of an Initial Dosing Regimen of Vancomycin and Development of a New Dosing Nomogram

W. Park, K. Yu, S. Song, 2018, Basic & clinical pharmacology & toxicology.

Effects of renal impairment on the pharmacokinetics and pharmacodynamics of a novel dipeptidyl peptidase‐4 inhibitor, evogliptin (DA‐1229)

A. Kim, Joo-Youn Cho, K. Yu, 2017, Diabetes, obesity & metabolism.

Effect of Food on the Pharmacokinetics and Pharmacodynamics of a Novel Dual Delayed‐Release Formulation of Esomeprazole in Healthy Subjects

I. Jang, SeungHwan Lee, Jina Jung, 2023, Clinical pharmacology in drug development.

Pharmacokinetic comparison of a new glimepiride 1-mg + metformin 500-mg combination tablet formulation and a glimepiride 2-mg + metformin 500-mg combination tablet formulation: a single-dose, randomized, open-label, two-period, two-way crossover study in healthy, fasting Korean male volunteers.

Joo-Youn Cho, K. Yu, Jung-Ryul Kim, 2009, Clinical therapeutics.

Theophylline pharmacokinetics are not altered by lansoprazole in CYP2C19 poor metabolizers

D. Flockhart, I. Jang, Jae-Gook Shin, 1999, Clinical pharmacology and therapeutics.

Pharmacokinetics and Pharmacodynamics of Esomezol DR, a New Dual Delayed-Release Formulation of Esomeprazole 20 Mg or 40 Mg, in Healthy Subjects.

I. Jang, SeungHwan Lee, Jina Jung, 2023, Drug design, development and therapy.

LBEC0101, A Proposed Etanercept Biosimilar: Pharmacokinetics, Immunogenicity, and Tolerability Profiles Compared with a Reference Biologic Product in Healthy Male Subjects

Joo-Youn Cho, K. Yu, I. Jang, 2017, BioDrugs.

Pharmacokinetics, safety and tolerability of valbenazine in Korean CYP2D6 normal and intermediate metabolizers

K. Yu, I. Jang, Jaeseong Oh, 2022, Clinical and translational science.

The Association between the T102C Polymorphism of Serotonin-2A Receptor Gene and Neurocognitive Function in Obsessive Compulsive Disorder

J. Kwon, D. Kang, Joo-Youn Cho, 2007 .

Pharmacokinetic-pharmacodynamic modeling of risperidone effects on electroencephalography in healthy volunteers

Dong Young Lee, Jun Soo Kwon, D. Y. Lee, 1999, Psychopharmacology.

Effects of renal impairment on the pharmacokinetics and pharmacodynamics of a novel DPP-IV inhibitor , evogliptin ( DA-1229 )

Joo-Youn Cho, K. Yu, I. Jang, 2016 .

Pharmacokinetic comparison using two tablets of an evogliptin/metformin XR 2.5/500 mg fixed dose combination vs. 1 tablet each of evogliptin 5 mg and metformin XR 1,000 mg .

Sang-In Park, Sumin Yoon, Joo-Youn Cho, 2017, International journal of clinical pharmacology and therapeutics.

Comparison of Pharmacokinetics and Safety of Ranolazine PR between Koreans and Caucasians.

Joo-Youn Cho, K. Yu, I. Jang, 2021, Clinical Therapeutics.

Tolerability and Pharmacokinetics of Lobeglitazone, a Novel Peroxisome Proliferator-Activated Receptor-γ Agonist, After a Single Oral Administration in Healthy Female Subjects

Joo-Youn Cho, K. Yu, I. Jang, 2014, Clinical Drug Investigation.

Artificial intelligence in drug development: clinical pharmacologist perspective

I. Jang, 2019, Translational and clinical pharmacology.

Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity

Joo-Youn Cho, K. Yu, I. Jang, 2018, Genomics & informatics.

I. Jang, S. Willmann, A. Edginton, 2022 .

HAPLOTYPE STRUCTURE AND ALLELE FREQUENCIES OF CYP2B6 IN A KOREAN POPULATION

Joo-Youn Cho, K. Yu, Hyeong-Seok Lim, 2004, Drug Metabolism and Disposition.

Pharmacodynamic and Pharmacokinetic Drug Interactions between Fexuprazan, a Novel Potassium-Competitive Inhibitor, and Aspirin, in Healthy Subjects

I. Jang, SeungHwan Lee, Jaeseong Oh, 2023, Pharmaceutics.

Assessment of the Analgesic Effect of Remifentanil using Three Pain Models in Healthy Korean Volunteers: A Randomized, Controlled Study

K. Yu, I. Jang, Tae-Eun Kim, 2012, Basic & clinical pharmacology & toxicology.

Pharmacokinetic interaction between fimasartan and atorvastatin in healthy male volunteers

K. Yu, I. Jang, SeungHwan Lee, 2018, Drug design, development and therapy.

Dynamically simulating the interaction of midazolam and the CYP3A4 inhibitor itraconazole using individual coupled whole-body physiologically-based pharmacokinetic (WB-PBPK) models

I. Jang, S. Willmann, A. Edginton, 2007, Theoretical Biology and Medical Modelling.

Ji Won Lee, N. Kim, June-Dong Park, 2015, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Joo-Youn Cho, K. Yu, I. Jang, 2010, Clinical therapeutics.

The HLA‐A*2402/Cw*0102 haplotype is associated with lamotrigine‐induced maculopapular eruption in the Korean population

K. Chu, Soon-Tae Lee, J. Sunwoo, 2015, Epilepsia.

Pharmacokinetics, Tolerability and Pharmacogenetics of DA-8031 After Multiple Ascending Doses in Healthy Male Subjects

Joo-Youn Cho, K. Yu, I. Jang, 2021, Drug design, development and therapy.

K. Yu, Jung-Ryul Kim, I. Jang, 2010, Clinical therapeutics.

Pharmacokinetic Proﬁles of Ceftazidime after Intravenous Administration in Patients Undergoing Automated Peritoneal Dialysis

C. Ahn, K. Oh, Y. Hwang, 2011 .

Modeling of Brain D2 Receptor Occupancy‐Plasma Concentration Relationships with a Novel Antipsychotic, YKP1358, Using Serial PET Scans in Healthy Volunteers

Jae Kyeong Jeong, H W Kim, H. Kim, 2007, Clinical pharmacology and therapeutics.

Exploration of Optimal Dosing Regimens of Haloperidol, a D2 Antagonist, via Modeling and Simulation Analysis in a D2 Receptor Occupancy Study

Hyeong-Seok Lim, I. Jang, Sang Eun Kim, 2013, Pharmaceutical Research.