C. Chou

发表

Deep Sequencing in Microdissected Renal Tubules Identifies Nephron Segment-Specific Transcriptomes.

Jae Wook Lee, M. Knepper, C. Chou, 2015, Journal of the American Society of Nephrology : JASN.

Oxytocin as an antidiuretic hormone. II. Role of V2 vasopressin receptor.

M. Knepper, S. Digiovanni, S. Lolait, 1995, The American journal of physiology.

Aquaporin-2 in the “-omics” Era*

M. Knepper, J. Hoffert, C. Chou, 2009, Journal of Biological Chemistry.

Role of proximal convoluted tubule in pressure diuresis in the rat.

D. Marsh, C. Chou, 1986, The American journal of physiology.

Measurement of flow rate in rat proximal tubules with a nonobstructing optical method.

D. Marsh, C. Chou, 1987, The American journal of physiology.

Time course of proximal tubule response to acute arterial hypertension in the rat.

D. Marsh, C. Chou, 1988, The American journal of physiology.

Regulation of collecting duct water permeability independent of cAMP-mediated AVP response.

J. Wade, M. Knepper, C. Chou, 1991, The American journal of physiology.

Experimental tests of three-dimensional model of urinary concentrating mechanism.

J. Han, M. Knepper, J. Han, 1992, Journal of the American Society of Nephrology : JASN.

In vitro perfusion of chinchilla thin limb segments: urea and NaCl permeabilities.

M. Knepper, C. Chou, 1993, The American journal of physiology.

Permeability criteria for effective function of passive countercurrent multiplier.

M. Knepper, C. Chou, H. Layton, 1996, The American journal of physiology.

features of glomerular parietal cells Atlas of gene expression in the mouse kidney: new

Jae Wook Lee, J. Poulain, J. Weissenbach, 2015 .

A selective EP4 PGE2 receptor agonist alleviates disease in a new mouse model of X-linked nephrogenic diabetes insipidus.

J. Wess, C. Deng, B. Li, 2009, The Journal of clinical investigation.

Roles of basolateral solute uptake via NKCC1 and of myosin II in vasopressin-induced cell swelling in inner medullary collecting duct.

M. Knepper, J. Hoffert, Ming-Jiun Yu, 2008, American journal of physiology. Renal physiology.

Evidence for dual signaling pathways for V2 vasopressin receptor in rat inner medullary collecting duct.

M. Knepper, S. Digiovanni, S. Lolait, 1996, The American journal of physiology.

Syntaxin-4 is localized to the apical plasma membrane of rat renal collecting duct cells: possible role in aquaporin-2 trafficking.

S. Nielsen, M. Knepper, C. Chou, 1996, The Journal of clinical investigation.

Regulation of Aquaporin-2 Trafficking by Vasopressin in the Renal Collecting Duct

K. Kador, J. Wade, M. Knepper, 2000, The Journal of Biological Chemistry.

Non-muscle Myosin II and Myosin Light Chain Kinase Are Downstream Targets for Vasopressin Signaling in the Renal Collecting Duct*

Ravi A. Desai, S. Nielsen, H. Vorum, 2004, Journal of Biological Chemistry.

Structural-functional correlation in chinchilla long loop of Henle thin limbs: a novel papillary subsegment.

S. Nielsen, M. Knepper, C. Chou, 1993, The American journal of physiology.

Urinary concentrating mechanism: the role of the inner medulla.

M. Knepper, C. Chou, H. Layton, 1993, Seminars in nephrology.

Defective proximal tubular fluid reabsorption in transgenic aquaporin-1 null mice.

A. Verkman, M. Knepper, J. Schnermann, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Targeted Single-Cell RNA-seq Identifies Minority Cell Types of Kidney Distal Nephron.

M. Knepper, C. Chou, Lihe Chen, 2021, Journal of the American Society of Nephrology : JASN.

Reduced water permeability and altered ultrastructure in thin descending limb of Henle in aquaporin-1 null mice.

A. Verkman, Dennis Brown, Baoxue Yang, 1999, The Journal of clinical investigation.

Landscape of GPCR Expression along the Mouse Nephron.

M. Knepper, C. Chou, Lihe Chen, 2021, American journal of physiology. Renal physiology.

"ADPKD-omics":Determinants of Cyclic AMP Levels in Renal Epithelial Cells.

Chin-Rang Yang, S. Khundmiri, M. Knepper, 2021, Kidney international.

Bayesian analysis of dynamic phosphoproteomic data identifies protein kinases mediating GPCR responses

Chin-Rang Yang, M. Knepper, C. Chou, 2022, Cell communication and signaling : CCS.

Proteomic and Metabolomic Approaches to Cell Physiology and Pathophysiology Use of LC-MS / MS and Bayes ’ theorem to identify protein kinases that phosphorylate aquaporin-2 at Ser 256

T. Pisitkun, M. Knepper, J. Hoffert, 2014 .

Large-scale phosphotyrosine proteomic profiling of rat renal collecting duct epithelium reveals predominance of proteins involved in cell polarity determination.

T. Pisitkun, M. Knepper, C. Chou, 2012, American journal of physiology. Cell physiology.

Application of difference gel electrophoresis to the identification of inner medullary collecting duct proteins.

B. W. van Balkom, M. Knepper, J. Hoffert, 2004, American journal of physiology. Renal physiology.

Systems-level analysis of cell-specific AQP2 gene expression in renal collecting duct

Markus M. Rinschen, R. Miller, T. Pisitkun, 2009, Proceedings of the National Academy of Sciences.

Vasopressin regulates apical targeting of aquaporin-2 but not of UT1 urea transporter in renal collecting duct.

S. Nielsen, M. Knepper, C. Chou, 1999, The American journal of physiology.

97- and 117-kDa forms of collecting duct urea transporter UT-A1 are due to different states of glycosylation.

M. Knepper, J. Sands, C. Chou, 2001, American journal of physiology. Renal physiology.

Identification of β-catenin-interacting proteins in nuclear fractions of native rat collecting duct cells.

M. Knepper, Hyun Jun Jung, M. Knepper, 2017, American journal of physiology. Renal physiology.

Gamble's "economy of water" revisited: studies in urea transporter knockout mice.

M. Knepper, R. Fenton, C. Chou, 2006, American journal of physiology. Renal physiology.

Urinary concentrating defect in mice with selective deletion of phloretin-sensitive urea transporters in the renal collecting duct.

M. Knepper, R. Fenton, C. Chou, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Increased collecting duct urea transporter expression in Dahl salt-sensitive rats.

J. Stokes, M. Knepper, R. Fenton, 2003, American journal of physiology. Renal physiology.

Roflumilast and aquaporin‐2 regulation in rat renal inner medullary collecting duct

M. Knepper, C. Chou, Yanhua Wang, 2017, Physiological reports.

Terbutaline acts at multiple sites to inhibit bronchoconstriction induced by dry air in canine peripheral airways.

C. Chou, H. I. Chen, A. Freed, 1992, The American review of respiratory disease.

Early Signaling Events in Renal Compensatory Hypertrophy Revealed by Multi-Omics

Chin-Rang Yang, M. Knepper, Hyun Jun Jung, 2022, bioRxiv.

Flow resistance along the rat renal tubule.

M. Knepper, C. Chou, G. Gilmer, 2018, American journal of physiology. Renal physiology.

PKA‐independent vasopressin signaling in renal collecting duct

Markus M. Rinschen, Chin-Rang Yang, Arnab Datta, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Quantitative analysis of aquaporin-2 phosphorylation.

T. Pisitkun, M. Knepper, J. Hoffert, 2010, American journal of physiology. Renal physiology.

Magnetic resonance imaging of urea transporter knockout mice reveals two distinct types of renal pelvic abnormality

M. Knepper, R. Fenton, J. Schnermann, 2009 .

Magnetic resonance imaging of urea transporter knockout mice shows renal pelvic abnormalities.

S. Anderson, M. Knepper, R. Fenton, 2008, Kidney international.

Altered expression profile of transporters in the inner medullary collecting duct of aquaporin-1 knockout mice.

M. Knepper, H. Brooks, S. Uchida, 2005, American journal of physiology. Renal physiology.

Altered Expression Profile of Transporters in the IMCD of Aquaporin 1 Knockout Mice

M. Knepper, H. Brooks, S. Uchida, 2005 .

Calmodulin Is Required for Vasopressin-stimulated Increase in Cyclic AMP Production in Inner Medullary Collecting Duct*

M. Knepper, J. Hoffert, R. Fenton, 2005, Journal of Biological Chemistry.

Fourfold reduction of water permeability in inner medullary collecting duct of aquaporin-4 knockout mice.

A. Verkman, Baoxue Yang, M. Knepper, 1998, American journal of physiology. Cell physiology.

Mechanism of vasopressin action in the renal collecting duct.

S. Nielsen, M. Knepper, S. Digiovanni, 1994, Seminars in nephrology.

Fourfold reduction of water permeability in inner medullary collecting duct of aquaporin-4 knockout mice.

A. Verkman, M. Knepper, C. Chou, 1998, The American journal of physiology.

Chapter 3 Physiological rolesof aquaporins in the kidney

S. Nielsen, M. Knepper, C. Chou, 2001 .

A Comprehensive Map of mRNAs and Their Isoforms across All 14 Renal Tubule Segments of Mouse.

M. Knepper, C. Chou, Lihe Chen, 2021, Journal of the American Society of Nephrology : JASN.

Extracellular nucleotide receptor inhibits AVP-stimulated water permeability in inner medullary collecting duct.

B. Kishore, M. Knepper, C. Chou, 1995, The American journal of physiology.

Concentration dependence of urea and thiourea transport in rat inner medullary collecting duct.

M. Knepper, H. Nonoguchi, J. Sands, 1990, The American journal of physiology.

Inhibition of urea transport in inner medullary collecting duct by phloretin and urea analogues.

M. Knepper, C. Chou, 1989, The American journal of physiology.

Vasopressin increases water permeability of kidney collecting duct by inducing translocation of aquaporin-CD water channels to plasma membrane.

S. Nielsen, B. Kishore, M. Knepper, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Akt and ERK1/2 pathways are components of the vasopressin signaling network in rat native IMCD.

S. Schleicher, T. Pisitkun, M. Knepper, 2008, American journal of physiology. Renal physiology.

Representation and relative abundance of cell-type selective markers in whole-kidney RNA-Seq data.

Mark A Knepper, Jae Wook Lee, Jevin Z. Clark, 2019, Kidney international.

Targeted single-cell RNA-seq identifies minority cell types of kidney distal nephron that regulate blood pressure and calcium balance

M. Knepper, C. Chou, Lihe Chen, 2020, bioRxiv.

Transcriptomes of major renal collecting duct cell types in mouse identified by single-cell RNA-seq

Mark A. Knepper, Maurice B. Burg, Sylvie Breton, 2017, Proceedings of the National Academy of Sciences.

Renal aquaporins.

J. Wade, S. Nielsen, B. Kishore, 1996, Kidney international.

Phosphoproteomic profiling reveals vasopressin-regulated phosphorylation sites in collecting duct.

E. Boja, Guanghui Wang, T. Pisitkun, 2010, Journal of the American Society of Nephrology : JASN.

Vasopressin regulates apical targeting of aquaporin-2 but not of UT1 urea transporter in renal collecting duct.

S. Nielsen, M. Knepper, C. Chou, 1999, American journal of physiology. Renal physiology.

In vitro perfusion of chinchilla thin limb segments: segmentation and osmotic water permeability.

M. Knepper, C. Chou, M A Knepper, 1992, The American journal of physiology.

Single-tubule RNA-Seq uncovers signaling mechanisms that defend against hyponatremia in SIADH.

Jae Wook Lee, P. Deen, M. Knepper, 2018, Kidney international.

Phosphoinositide signaling in rat inner medullary collecting duct.

M. Knepper, C. Chou, S. I. Rapko, 1998, American journal of physiology. Renal physiology.

Oxytocin as an antidiuretic hormone. I. Concentration dependence of action.

R. Mejia, S. Nielsen, M. Knepper, 1995, The American journal of physiology.

Letter to the editor: "Systems biology versus reductionism in cell physiology".

T. Pisitkun, M. Knepper, J. Hoffert, 2014, American journal of physiology. Cell physiology.

Use of LC-MS/MS and Bayes' theorem to identify protein kinases that phosphorylate aquaporin-2 at Ser256.

T. Pisitkun, M. Knepper, J. Hoffert, 2014, American journal of physiology. Cell physiology.

Dynamics of the G Protein-coupled Vasopressin V2 Receptor Signaling Network Revealed by Quantitative Phosphoproteomics*

Fahad Saeed, Trairak Pisitkun, Jason D Hoffert, 2011, Molecular & Cellular Proteomics.

Transcriptomes of major renal collecting duct cell types in mouse identified by single-cell RNA-seq

Jae Wook Lee, Dennis Brown, T. Paunescu, 2017, Proceedings of the National Academy of Sciences.

Circadian Gene Expression in Mouse Renal Proximal Tubule

Chin-Rang Yang, M. Knepper, Hyun Jun Jung, 2022, bioRxiv.

How is urine concentrated by the renal inner medulla?

M. Knepper, C. Chou, H. Layton, 1993, Contributions to nephrology.

Quantitative Proteomics of All 14 Renal Tubule Segments in Rat.

M. Knepper, C. Chou, Kavee Limbutara, 2020, Journal of the American Society of Nephrology : JASN.

Intrarenal mechanisms mediating pressure natriuresis: role of angiotensin and prostaglandins.

R. V. Paul, D. Marsh, C. Chou, 1986, Federation proceedings.

Tolvaptan as a tool in renal physiology.

Jae Wook Lee, M. Knepper, C. Chou, 2014, American journal of physiology. Renal physiology.

Large Scale Protein Identification in Intracellular Aquaporin-2 Vesicles from Renal Inner Medullary Collecting Duct*S

Rong-Fong Shen, T. Pisitkun, M. Knepper, 2005, Molecular & Cellular Proteomics.

Vasopressin increases phosphorylation of Ser84 and Ser486 in Slc14a2 collecting duct urea transporters.

Markus M. Rinschen, T. Pisitkun, M. Knepper, 2010, American journal of physiology. Renal physiology.

Proteomic analysis of long-term vasopressin action in the inner medullary collecting duct of the Brattleboro rat.

B. W. van Balkom, M. Knepper, J. Hoffert, 2004, American journal of physiology. Renal physiology.

Quantitative phosphoproteomic analysis reveals cAMP/vasopressin-dependent signaling pathways in native renal thick ascending limb cells

Markus M. Rinschen, T. Pisitkun, M. Knepper, 2010, Proceedings of the National Academy of Sciences.

"SLC-omics" of the kidney: Solute transporters along the nephron.

Chin-Rang Yang, M. Knepper, S. Khundmiri, 2021, American journal of physiology. Cell physiology.

Label-free protein quantification using LC-coupled ion trap or FT mass spectrometry: Reproducibility, linearity, and application with complex proteomes.

Guanghui Wang, Guanghui Wang, Rong-Fong Shen, 2006, Journal of proteome research.

Escape from vasopressin-induced antidiuresis: role of vasopressin resistance of the collecting duct.

J. Verbalis, M. Knepper, S. Digiovanni, 1998, The American journal of physiology.

RNA-Seq and protein mass spectrometry in microdissected kidney tubules reveal signaling processes initiating lithium-induced nephrogenic diabetes insipidus.

Chin-Rang Yang, M. Knepper, Shih-Hua Lin, 2019, Kidney international.

RNA-Seq and Protein Mass Spectrometry in Microdissected Kidney Tubules Reveal Signaling Processes that Initiate Lithium-Induced Diabetes Insipidus

Chin-Rang Yang, M. Knepper, Shih-Hua Lin, 2018, bioRxiv.

Escape from vasopressin-induced antidiuresis: role of vasopressin resistance of the collecting duct.

Mark A Knepper, J. Verbalis, M. Knepper, 1998, American journal of physiology. Renal physiology.

Phosphoproteomic Identification of Vasopressin-Regulated Protein Kinases in Collecting Duct Cells

Chin-Rang Yang, Arnab Datta, M. Knepper, 2020, bioRxiv.

Phosphoproteomic Identification of Vasopressin/cAMP/Protein Kinase A–Dependent Signaling in Kidney

Chin-Rang Yang, Arnab Datta, M. Knepper, 2020, Molecular Pharmacology.

Multiomics Analyses Reveal Sex Differences in Mouse Renal Proximal Subsegments

Chin-Rang Yang, M. Knepper, C. Chou, 2023, Journal of the American Society of Nephrology : JASN.

Cell-Type Selective Markers Represented in Whole-Kidney RNA-Seq Data

Jae Wook Lee, Jevin Z. Clark, M. Knepper, 2018, bioRxiv.

Phosphoproteomic Identification of Vasopressin V2 Receptor-Dependent Signaling in the Renal Collecting Duct.

Arnab Datta, M. Knepper, C. Chou, 2019, American journal of physiology. Renal physiology.

Proteomic profiling of nuclear fractions from native renal inner medullary collecting duct cells.

Chin-Rang Yang, M. Knepper, Hyun Jun Jung, 2016, Physiological genomics.

Kinetics of urea and water permeability activation by vasopressin in rat terminal IMCD.

J. Han, M. Knepper, C. Chou, 1992, The American journal of physiology.

Independence of urea and water transport in rat inner medullary collecting duct.

M. Knepper, J. Sands, C. Chou, 1989, American Journal of Physiology.

Identification of UT-A1- and AQP2-interacting proteins in rat inner medullary collecting duct.

T. Pisitkun, M. Knepper, C. Chou, 2018, American journal of physiology. Cell physiology.

Endogenous Carbamylation of Renal Medullary Proteins

M. Knepper, J. Hoffert, C. Chou, 2013, PloS one.

Systems Biology of the Vasopressin V2 Receptor: New Tools for Discovery of Molecular Actions of a GPCR.

Chin-Rang Yang, Arnab Datta, M. Knepper, 2021, Annual Review of Pharmacology and Toxicology.

Early Molecular Events Mediating Loss of Aquaporin-2 during Ureteral Obstruction in Rats

Chin-Rang Yang, M. Knepper, Shih-Hua Lin, 2022, Journal of the American Society of Nephrology : JASN.

Signaling mechanisms in renal compensatory hypertrophy revealed by multi-omics

A. Remaley, Chin-Rang Yang, M. Knepper, 2023, Nature communications.

Serine/threonine phosphatases and aquaporin-2 regulation in renal collecting duct.

M. Knepper, C. Chou, C. M. Pickering, 2017, American journal of physiology. Renal physiology.

Phosphoinositide signaling in rat inner medullary collecting duct.

M. Knepper, C. Chou, S. I. Rapko, 1998, The American journal of physiology.

Cyclooxygenase pathway mediates lung injury induced by phorbol and platelets.

C. Chou, H. I. Chen, K. Hsu, 1991, Journal of applied physiology.

Reply to Edemir: Physiological regulation and single-cell RNA sequencing

Jae Wook Lee, Dennis Brown, T. Paunescu, 2018, Proceedings of the National Academy of Sciences.

Bayesian Identification of Candidate Transcription Factors for Regulation of Aqp2 Gene Expression.

Chin-Rang Yang, M. Knepper, Hyun Jun Jung, 2021, American journal of physiology. Renal physiology.

Urea gradient-associated fluid absorption with sigma urea = 1 in rat terminal collecting duct.

M. Knepper, H. Nonoguchi, J. Sands, 1990, American Journal of Physiology.

Large Scale Protein Identification in Intracellular Aquaporin-2 Vesicles from Renal Inner Medullary Collecting Duct*S

T. Pisitkun, M. Knepper, Ming-Jiun Yu, 2005, Molecular & Cellular Proteomics.

Identiﬁcation of (cid:2) -catenin-interacting proteins in nuclear fractions of native rat collecting duct cells

M. Knepper, C. Chou, Barbara Medvar, 2017 .

Phosphoproteomic Identification of Vasopressin / cAMP / PKA-Dependent Signaling in Kidney 1 by

Arnab Datta, M. Knepper, C. Chou, 2020 .

Regulation of Renal Aquaporins and Sodium Transporters During Vasopressin-Escape in the Rat

J. Verbalis, S. Nielsen, M. Knepper, 2000 .

Akt and ERK1/2 pathways are components of the vasopressin signaling network in rat native IMCD.

S. Schleicher, T. Pisitkun, M. Knepper, 2008, American journal of physiology. Renal physiology.

Vasopressin V2 receptor, tolvaptan, and ERK1/2 phosphorylation in the renal collecting duct

Chin-Rang Yang, M. Knepper, S. Khundmiri, 2023, American journal of physiology. Renal physiology.

Proteomics and AQP2 regulation

Chin-Rang Yang, Arnab Datta, C. Chou, 2022, The Journal of physiology.

CRISPR-Cas9/Phosphoproteomics Identifies Multiple Non-canonical Targets of Myosin Light Chain Kinase.

Chin-Rang Yang, M. Knepper, C. Chou, 2020, American journal of physiology. Renal physiology.