Melanie Isau

The power of NGS technologies to delineate the genome organization in cancer: from mutations to structural variations and epigenetic alterations

B. Timmermann, M. Kerick, M. Schweiger, 2011, Cancer and Metastasis Reviews.

Somatic Mutation Profiles of MSI and MSS Colorectal Cancer Identified by Whole Exome Next Generation Sequencing and Bioinformatics Analysis

H. Lehrach, M. Lappe, K. Zatloukal, 2010, PloS one.

Identity-by-descent filtering of exome sequence data identifies PIGV mutations in hyperphosphatasia mental retardation syndrome

Sebastian Bauer, Sebastian Köhler, Christian Rödelsperger, 2010, Nature Genetics.

Targeted high throughput sequencing in clinical cancer Settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity

Ralf Herwig, Hans Lehrach, Holger Sültmann, 2011, BMC Medical Genomics.

FOX-2 Dependent Splicing of Ataxin-2 Transcript Is Affected by Ataxin-1 Overexpression

H. Lehrach, S. Krobitsch, Linda Hallén, 2012, PloS one.

Genome-wide DNA methylation events in TMPRSS2-ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation.

M. Rubin, C. Plass, H. Lehrach, 2012, Cancer discovery.