K. Oualkacha

发表

A smoothed EM-algorithm for DNA methylation profiles from sequencing-based methods in cell lines or for a single cell type

C. Greenwood, B. Abdous, L. Lakhal-Chaieb, 2017, Statistical applications in genetics and molecular biology.

The UK10K project identifies rare variants in health and disease

Tom R. Gaunt, Hashem A. Shihab, Gail P. Clement, 2016 .

Constrained instruments and their application to Mendelian randomization with pleiotropy

C. Greenwood, A. Ciampi, V. Didelez, 2017, bioRxiv.

Simultaneous SNP selection and adjustment for population structure in high dimensional prediction models

C. Greenwood, J. Loredo-Osti, K. Oualkacha, 2020, PLoS genetics.

Weighted asymmetric least squares regression for longitudinal data using GEE

Arthur Charpentier, K. Oualkacha, A. Barry, 2018, 1810.09214.

Specific expression of novel long non-coding RNAs in high-hyperdiploid childhood acute lymphoblastic leukemia

D. Sinnett, C. Richer, M. Caron, 2017, PloS one.

A rare variant association test in family‐based designs and non‐normal quantitative traits

C. Greenwood, L. Lakhal-Chaieb, K. Oualkacha, 2016, Statistics in medicine.

Principal Components of Heritability for High Dimension Quantitative Traits and General Pedigrees

A. Ciampi, A. Labbe, M. Maziade, 2012, Statistical applications in genetics and molecular biology.

Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity

Tom R. Gaunt, Thomas M. Keane, Hashem A. Shihab, 2017, Scientific Reports.

Gene Coexpression Analyses Differentiate Networks Associated with Diverse Cancers Harboring TP53 Missense or Null Mutations

Karim Oualkacha, Sahir Bhatnagar, Celia M. T. Greenwood, 2016, Front. Genet..

Universitet Low-frequency variation in TP 53 has large effects on head circumference and intracranial

Tom R. Gaunt, Thomas M. Keane, Hashem A. Shihab, 2019 .

Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

Tom R. Gaunt, Hashem A. Shihab, Gail P. Clement, 2018, bioRxiv.

Constrained instruments and their application to Mendelian randomization with pleiotropy

Antonio Ciampi, Pedro Rosa, Lai Jiang, 2017, bioRxiv.

Efficient Penalized Generalized Linear Mixed Models for Variable Selection and Genetic Risk Prediction in High-Dimensional Data

K. Oualkacha, J. St-Pierre, S. Bhatnagar, 2022, 2206.12267.

CpG-set association assessment of lipid concentration changes and DNA methylation

C. Greenwood, Lai Jiang, Kaiqiong Zhao, 2018, BMC Proceedings.

Efficient penalized generalized linear mixed models for variable selection and genetic risk prediction in high-dimensional data

K. Oualkacha, J. St-Pierre, S. Bhatnagar, 2022, Bioinform..

Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis

Tom R. Gaunt, Thomas M. Keane, Hashem A. Shihab, 2019, Nature Communications.

Quantile and Expectile Regression for random effects model

Arthur Charpentier, K. Oualkacha, A. Barry, 2016 .

A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans

Gail Clement, Jie Huang, Antonio Ciampi, 2014, Nature Communications.

A copula-based set-variant association test for bivariate continuous, binary or mixed phenotypes

K. Oualkacha, Julien St-Pierre, 2022, The international journal of biostatistics.

Performance of an allele‐level multi‐locus HLA genotype imputation tool in hematopoietic stem cell donors from Quebec

K. Oualkacha, R. Sapir-Pichhadze, C. Saw, 2017, Immunity, inflammation and disease.

Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

Tom R. Gaunt, Thomas M. Keane, Chin Yang Shapland, 2018, bioRxiv.

A coordinate descent algorithm for computing penalized smooth quantile regression

A. Mkhadri, Mohamed Ouhourane, K. Oualkacha, 2016, Statistics and Computing.

The cluster correlation-network support vector machine for high-dimensional binary classification

Karim Oualkacha, Abdallah Mkhadri, A. Mkhadri, 2019, Journal of Statistical Computation and Simulation.

A new GEE method to account for heteroscedasticity using asymmetric least-square regressions

Karim Oualkacha, Arthur Charpentier, Amadou Barry, 2021, Journal of applied statistics.

Group penalized quantile regression

Mohamed Ouhourane, K. Oualkacha, A. Benedet, 2021, Statistical Methods & Applications.

Software Application Profile: RVPedigree: a suite of family-based rare variant association tests for normally and non-normally distributed quantitative traits.

C. Greenwood, L. Lakhal-Chaieb, K. Oualkacha, 2016, International journal of epidemiology.

Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel

Tom R. Gaunt, Klaudia Walter, Nicholas J Timpson, 2015, Nature Communications.

Principal component of explained variance: An efficient and optimal data dimension reduction framework for association studies

Antonio Ciampi, Aurélie Labbe, Pedro Rosa-Neto, 2016, bioRxiv.

Joint analysis of multiple blood pressure phenotypes in GAW19 data by using a multivariate rare-variant association test

C. Greenwood, A. Ciampi, K. Oualkacha, 2016, BMC Proceedings.

Causal modeling in a multi-omic setting: insights from GAW20

A. Justice, S. Aslibekyan, Lai Jiang, 2018, BMC Genetics.

Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity

Tom R. Gaunt, Thomas M. Keane, Hashem A. Shihab, 2017, Scientific Reports.

UK 10 K Consortium

Tom R. Gaunt, Hashem A. Shihab, Gail P. Clement, 2019 .

Exome-wide rare variant analyses of two bone mineral density phenotypes: the challenges of analyzing rare genetic variation

C. Greenwood, H. Zheng, J. Richards, 2018, Scientific Reports.

Detecting differentially methylated regions in bisulfite sequencing data using quasi-binomial mixed models with smooth covariate effect estimates

Karim Oualkacha, Marie Hudson, Kaiqiong Zhao, 2021, 2101.07374.

A novel statistical method for modeling covariate effects in bisulfite sequencing derived measures of DNA methylation

Aurélie Labbe, Karim Oualkacha, Marie Hudson, 2020, Biometrics.

Block coordinate descent algorithm improves variable selection and estimation in error‐in‐variables regression

C. Greenwood, J. Richards, K. Oualkacha, 2021, Genetic epidemiology.

Dissecting the impact of molecular T-cell HLA mismatches in kidney transplant failure: A retrospective cohort study

C. Polychronakos, F. Claas, D. Fleischer, 2022, Frontiers in Immunology.

The Kendall interaction filter for variable interaction screening in high dimensional classification problems

Karim Oualkacha, Abdallah Mkhadri, Youssef Anzarmou, 2020, Journal of applied statistics.

A method for analyzing multiple continuous phenotypes in rare variant association studies allowing for flexible correlations in variant effects

Antonio Ciampi, Karim Oualkacha, Vincenzo Forgetta, 2016, European Journal of Human Genetics.

A General Framework for Variable Selection in Linear Mixed Models with Applications to Genetic Studies with Structured Populations

Yi Yang, Marie Forest, Celia M. T. Greenwood, 2018, bioRxiv.

On Path to Informing Hierarchy of Eplet Mismatches as Determinants of Kidney Transplant Loss

F. Claas, P. Keown, K. Oualkacha, 2021, Kidney international reports.

High-Dimensional Penalized Bernstein Support Vector Machines

A. Mkhadri, K. Oualkacha, Rachid Kharoubi, 2023, ArXiv.

A flexible copula‐based approach for the analysis of secondary phenotypes in ascertained samples

C. Greenwood, K. Oualkacha, G. Lefebvre, 2019, Statistics in medicine.

A new statistical model for random unit vectors

Karim Oualkacha, Louis-Paul Rivest, L. Rivest, 2009, J. Multivar. Anal..

Corrigendum: TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport

Gail Clement, Jie Huang, Inês Barroso, 2016, Nature Communications.

A coordinate descent algorithm for computing penalized smooth quantile regression

Karim Oualkacha, Abdallah Mkhadri, Mohamed Ouhourane, 2016, Statistics and Computing.

Investigating potential causal relationships between SNPs, DNA methylation and HDL

Angelo J. Canty, C. Greenwood, Lai Jiang, 2018, BMC Proceedings.

Adjusted Sequence Kernel Association Test for Rare Variants Controlling for Cryptic and Family Relatedness

Antonio Ciampi, Rui Li, Karim Oualkacha, 2013, Genetic epidemiology.

Inaccuracies in epitope repertoire estimations when using multilocus allele‐level HLA genotype imputation tools

K. Oualkacha, R. Sapir-Pichhadze, C. Saw, 2018, HLA.

The UK10K project identifies rare variants in health and disease

Tom R. Gaunt, Thomas M. Keane, Hashem A. Shihab, 2015, Nature.

TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport

Tom R. Gaunt, Thomas M. Keane, Colin A. Johnson, 2015, Nature Communications.

A copula-based set-variant association test for bivariate continuous or mixed phenotypes

Karim Oualkacha, Julien St-Pierre, K. Oualkacha, 2021, 2109.14467.

KSPM: A Package For Kernel Semi-Parametric Models

C. Greenwood, S. Jacquemont, A. Labbe, 2020, R J..

Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel

Tom R. Gaunt, Thomas M. Keane, Hashem A. Shihab, 2015, Nature Communications.

Statistical Applications in Genetics and Molecular Biology Principal Components of Heritability for High Dimension Quantitative Traits and General Pedigrees Principal Components of Heritability for High Dimension Quantitative Traits and General Pedigrees

M. Maziade, M. Roy, K. Oualkacha, 2022 .

Hierarchical selection of genetic and gene by environment interaction effects in high-dimensional mixed models

K. Oualkacha, Julien St-Pierre, 2023, 2312.13460.

On the estimation of an average rigid body motion

Karim Oualkacha, Louis-Paul Rivest, L. Rivest, 2012 .

Causal modeling in a multi-omic setting: insights from GAW20

A. Justice, S. Aslibekyan, Lai Jiang, 2018, BMC Genetics.