S. Tajima

发表

The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA

K. Mitsuya, Tetsuro Toyoda, M. Muto, 2007, Nature.

Processive Methylation of Hemimethylated CpG Sites by Mouse Dnmt1 DNA Methyltransferase*

S. Klimašauskas, G. Vilkaitis, I. Suetake, 2005, Journal of Biological Chemistry.

Mechanism‐Based Inhibitor of DNA Cytosine‐5 Methyltransferase by a SNAr Reaction with an Oligodeoxyribonucleotide Containing a 2‐Amino‐4‐Halopyridine‐C‐Nucleoside

A. Matsuda, I. Suetake, S. Tajima, 2018, Chembiochem : a European journal of chemical biology.

Isolation of the novel cDNA of a gene of which expression is induced by a demethylating stimulus.

I. Suetake, S. Tajima, M. Muguruma, 1999, Gene.

Maternal and zygotic Dnmt1 are necessary and sufficient for the maintenance of DNA methylation imprints during preimplantation development.

R. Jaenisch, E. Li, H. Sasaki, 2008, Genes & development.

Identification of two novel mouse nuclear proteins that bind selectively to a methylated c-Myc recognizing sequence.

I. Suetake, S. Tajima, A. Asano, 1993, Nucleic Acids Research.

Overexpression of DNA methyltransferase in myoblast cells accelerates myotube formation.

S. Tajima, H. Takagi, A. Asano, 1995, European journal of biochemistry.

A novel sensitive detection method for DNA methylation in circulating free DNA of pancreatic cancer

H. Aburatani, K. Matsuo, Hidemi Ito, 2020, PloS one.

The Dnmt3b splice variant is specifically expressed in in vitro-manipulated blastocysts and their derivative ES cells.

M. Kimura, T. Horii, S. Morita, 2011, The Journal of reproduction and development.

Biochemical fractionation reveals association of DNA methyltransferase (Dnmt) 3b with Dnmt1 and that of Dnmt 3a with a histone H3 methyltransferase and Hdac1

K. Ghoshal, J. Datta, S. Jacob, 2003, Journal of cellular biochemistry.

Establishment and Maintenance of DNA Methylation

I. Suetake, S. Tajima, H. Kimura, 2016 .

Expression of Dnmt3b in mouse hematopoietic progenitor cells and spermatogonia at specific stages.

I. Suetake, S. Tajima, D. Watanabe, 2004, Gene expression patterns : GEP.

A novel point mutation in a splice acceptor site of intron 1 of the human low density lipoprotein receptor gene which causes severe hypercholesterolemia: An unexpected absence of exon skipping

T. Funahashi, Y. Matsuzawa, T. Maruyama, 1998, Human mutation.

Siblings with normal LDL receptor activity and severe hypercholesterolemia.

S. Yokoyama, M. Harada‐Shiba, S. Tajima, 1992, Arteriosclerosis and thrombosis : a journal of vascular biology.

Stimulation effect of Dnmt3L on the DNA methylation activity of Dnmt3a2.

K. Abe, Takuya Fuchikami, I. Suetake, 2006, Journal of biochemistry.

Xenopus MBD3 plays a crucial role in an early stage of development.

S. Tajima, Masahiko Nakamura, H. Iwano, 2004, Developmental biology.

Proliferation stage-dependent expression of DNA methyltransferase (Dnmt1) in mouse small intestine.

S. Tajima, D. Watanabe, L. Shi, 2001, Cell structure and function.

Expression of DNA methyltransferase (Dnmt1) in testicular germ cells during development of mouse embryo.

M. Mizugaki, S. Yamashina, I. Suetake, 2001, Cell structure and function.

A Japanese family with high density lipoprotein deficiency.

S. Yokoyama, S. Tajima, A. Yamamoto, 1983, Atherosclerosis.

Expression, purification and characterization of methyl DNA binding protein from Bombyx mori

S. Tajima, T. Uno, K. Kanamaru, 2005, Journal of insect science.

Monoclonal antibody against dnmt1 arrests the cell division of xenopus early-stage embryos.

H. Hashimoto, I. Suetake, S. Tajima, 2003, Experimental cell research.

Mouse Dnmt3a preferentially methylates linker DNA and is inhibited by histone H1.

I. Suetake, S. Tajima, H. Takeshima, 2008, Journal of molecular biology.

Maintenance-type DNA methyltransferase is highly expressed in post-mitotic neurons and localized in the cytoplasmic compartment.

K. Inano, I. Suetake, S. Tajima, 2000, Journal of biochemistry.

Common mutations in the low-density-lipoprotein-receptor gene causing familial hypercholesterolemia in the Japanese population.

T. Funahashi, Y. Matsuzawa, T. Maruyama, 1995, Arteriosclerosis, thrombosis, and vascular biology.

A compound heterozygote for familial hypercholesterolaemia with a homozygous mother

S. Yamashita, T. Funahashi, Y. Matsuzawa, 1996, Journal of internal medicine.

A single point mutation in the splice donor site of the low-density-lipoprotein-receptor gene produces intron read-through, exon-skipped and cryptic-site-utilized transcripts.

T. Funahashi, Y. Matsuzawa, T. Maruyama, 1995, European journal of biochemistry.

Cyclin-dependent kinase-like 5 binds and phosphorylates DNA methyltransferase 1.

I. Suetake, S. Tajima, N. Hatano, 2008, Biochemical and biophysical research communications.

5-Hydroxymethylcytosine Marks Sites of DNA Damage and Promotes Genome Stability.

T. Horii, I. Hatada, I. Suetake, 2016, Cell reports.

Genomic organization of the mouse AZ1 gene that encodes the protein localized to preacrosomes of spermatids.

S. Tajima, H. Aoto, M. Nakamura, 1997, Genomics.

Simple and accurate single base resolution analysis of 5-hydroxymethylcytosine by catalytic oxidative bisulfite sequencing using micelle incarcerated oxidants.

I. Suetake, S. Tajima, K. Tachibana, 2016, Bioorganic & medicinal chemistry.

The DNA Methyltransferase Dnmt1 Directly Interacts with the SET and RING Finger-associated (SRA) Domain of the Multifunctional Protein Uhrf1 to Facilitate Accession of the Catalytic Center to Hemi-methylated DNA*

M. Shirakawa, A. Nakagawa, Ahmet C. Berkyurek, 2013, The Journal of Biological Chemistry.

A Novel method for the simultaneous identification of methylcytosine and hydroxymethylcytosine at a single base resolution

T. Kohda, F. Ishino, Y. Kuroda, 2016, Nucleic acids research.

Title 5-Hydroxymethylcytosine Marks Sites of DNA Damage andPromotes Genome Stability

T. Horii, I. Hatada, I. Suetake, 2018 .

Selective inhibition of a step of myotube formation with wheat germ agglutinin in a murine myoblast cell line, C2C12.

S. Tajima, H. Takagi, A. Asano, 1994, Cell structure and function.

Bmi1 cooperates with Dnmt1-associated protein 1 in gene silencing.

A. Iwama, H. Nakauchi, Y. Takasaki, 2007, Biochemical and biophysical research communications.

Distinct enzymatic properties of recombinant mouse DNA methyltransferases Dnmt3a and Dnmt3b.

C. Murakami, I. Suetake, S. Tajima, 2003, Journal of biochemistry.

The DNA-binding activity of mouse DNA methyltransferase 1 is regulated by phosphorylation with casein kinase 1delta/epsilon.

E. Kinoshita, Emiko Kinoshita-Kikuta, T. Koike, 2010, The Biochemical journal.

Isolation and expression of a chicken DNA methyltransferase cDNA.

K. Nishimori, S. Tajima, N. Wakabayashi, 1995, Journal of biochemistry.

The amino-terminus of mouse DNA methyltransferase 1 forms an independent domain and binds to DNA with the sequence involving PCNA binding motif.

I. Suetake, S. Tajima, D. Hayata, 2006, Journal of biochemistry.

DNMT1 regulates the timing of DNA methylation by DNMT3 in an enzymatic activity-dependent manner in mouse embryonic stem cells

M. Tada, L. Lefebvre, I. Suetake, 2022, PloS one.

Epigenetic Protection of Vertebrate Lymphoid Progenitor Cells by Dnmt1

K. Sikora, Y. Yonezawa, N. Iwanami, 2020, iScience.

Structure of the Dnmt1 Reader Module Complexed with a Unique Two-Mono-Ubiquitin Mark on Histone H3 Reveals the Basis for DNA Methylation Maintenance.

A. Kidera, M. Shirakawa, F. Ishikawa, 2017, Molecular cell.

A novel method to analyze 5-hydroxymethylcytosine in CpG sequences using maintenance DNA methyltransferase, DNMT1

J. Engelhardt, I. Suetake, S. Tajima, 2015, FEBS open bio.

Nucleosome compaction facilitates HP1γ binding to methylated H3K9

M. Shirakawa, T. Kawakami, I. Suetake, 2015, Nucleic acids research.

Three novel DNMT3B mutations in Japanese patients with ICF syndrome.

Y. Fukushima, H. Sasaki, I. Suetake, 2002, American journal of medical genetics.

Genome engineering of mammalian haploid embryonic stem cells using the Cas9/RNA system

T. Ochiya, M. Kimura, T. Horii, 2013, PeerJ.

Distinct DNA methylation activity of Dnmt3a and Dnmt3b towards naked and nucleosomal DNA.

I. Suetake, S. Tajima, S. Tate, 2006, Journal of biochemistry.

Recombinant Tol2 transposase with activity in Xenopus embryos

K. Kawakami, M. Asashima, M. Taira, 2007, FEBS letters.

Cell Cycle-Dependent Turnover of 5-Hydroxymethyl Cytosine in Mouse Embryonic Stem Cells

M. Shirakawa, T. Kawakami, H. Koseki, 2013, PloS one.

DNMT3L Stimulates the DNA Methylation Activity of Dnmt3a and Dnmt3b through a Direct Interaction*

I. Suetake, S. Tajima, H. Takeshima, 2004, Journal of Biological Chemistry.

PCNA clamp facilitates action of DNA cytosine methyltransferase 1 on hemimethylated DNA

C. Obuse, H. Morioka, S. Ohta, 2002, Genes to cells : devoted to molecular & cellular mechanisms.

Domain Structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA Methyltransferases.

A. Nakagawa, I. Suetake, S. Tajima, 2016, Advances in experimental medicine and biology.

Characterization of DNA-binding activity in the N-terminal domain of the DNA methyltransferase Dnmt3a.

T. Ikegami, I. Suetake, S. Tajima, 2011, The Biochemical journal.

Stage- and cell-specific expression of Dnmt3a and Dnmt3b during embryogenesis

T. Tada, I. Suetake, S. Tajima, 2002, Mechanisms of Development.

Enzymatic properties of de novo-type mouse DNA (cytosine-5) methyltransferases.

H. Sasaki, I. Suetake, S. Tajima, 2001, Nucleic acids research.

The epigenetic regulator Uhrf1 facilitates the proliferation and maturation of colonic regulatory T cells

Taeko Dohi, Shoji Tajima, Haruhiko Koseki, 2014, Nature Immunology.

Isolation of a novel cDNA that encodes a protein localized to the pre-acrosome region of spermatids.

Y. Nishimune, S. Tajima, Y. Nishina, 1995, European journal of biochemistry.

Abnormal DNA Methyltransferase Expression in Mouse Germline Stem Cells Results in Spermatogenic Defects1

S. Toyokuni, N. Nakatsuji, S. Takashima, 2009, Biology of reproduction.

The mTOR Pathway Controls Cell Proliferation by Regulating the FoxO3a Transcription Factor via SGK1 Kinase

S. Nada, M. Okada, C. Oneyama, 2014, PloS one.

Structural Basis of the Versatile DNA Recognition Ability of the Methyl-CpG Binding Domain of Methyl-CpG Binding Domain Protein 4*

M. Shirakawa, I. Suetake, S. Tajima, 2013, The Journal of Biological Chemistry.

Ars insulator identified in sea urchin possesses an activity to ensure the transgene expression in mouse cells.

M. Matsuoka, Jun Fan, S. Tajima, 2006, Journal of biochemistry.

Dual Functions of the RFTS Domain of Dnmt1 in Replication-Coupled DNA Methylation and in Protection of the Genome from Aberrant Methylation

M. Muto, H. Koseki, I. Suetake, 2015, PloS one.

Hinge and chromoshadow of HP1α participate in recognition of K9 methylated histone H3 in nucleosomes.

M. Shirakawa, H. Kimura, T. Kawakami, 2013, Journal of molecular biology.

Recombinant mammalian DNA methyltransferase activity on model transcriptional gene silencing short RNA-DNA heteroduplex substrates.

P. Molloy, I. Suetake, S. Tajima, 2010, The Biochemical journal.

Selective oxidation of 5-hydroxymethylcytosine with micelle incarcerated oxidants to determine it at single base resolution.

I. Suetake, S. Tajima, K. Tachibana, 2015, Bioorganic & medicinal chemistry letters.

miR-29 Represses the Activities of DNA Methyltransferases and DNA Demethylases

T. Ochiya, M. Kimura, T. Horii, 2013, International journal of molecular sciences.

Xenopus maintenance-type DNA methyltransferase is accumulated and translocated into germinal vesicles of oocytes.

I. Suetake, S. Tajima, H. Kimura, 1999, Journal of biochemistry.

Conserved threonine 1505 in the catalytic domain stabilizes mouse DNA methyltransferase 1

A. Nakagawa, I. Suetake, S. Tajima, 2017, Journal of biochemistry.

A Novel method for the simultaneous identification of methylcytosine and hydroxymethylcytosine at a single base resolution.

T. Kohda, F. Ishino, Y. Kuroda, 2016, Nucleic acids research.

Down-regulation of the Tumor Suppressor C-terminal Src Kinase (Csk)-binding Protein (Cbp)/PAG1 Is Mediated by Epigenetic Histone Modifications via the Mitogen-activated Protein Kinase (MAPK)/Phosphatidylinositol 3-Kinase (PI3K) Pathway*

M. Okada, C. Oneyama, S. Tajima, 2011, The Journal of Biological Chemistry.

Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1)

E. Yamashita, A. Nakagawa, I. Suetake, 2011, Proceedings of the National Academy of Sciences.

Regulation and function of DNA methylation in vertebrates.

I. Suetake, S. Tajima, S Tajima, 1998, Journal of biochemistry.

Co-expression of de novo DNA methyltransferases Dnmt3a2 and Dnmt3L in gonocytes of mouse embryos.

Shoji Tajima, Yasuhiro Sakai, S. Yamashina, 2004, Gene expression patterns : GEP.

Effect of aphidicolin on DNA methyltransferase in the nucleus.

I. Suetake, S. Tajima, Y. Kano, 1998, Cell structure and function.

Isolation and expression of a Xenopus laevis DNA methyltransferase cDNA.

S. Tajima, G. Ishihara, H. Kimura, 1996, Journal of biochemistry.

The signal recognition particle receptor is a complex that contains two distinct polypeptide chains

V. L. Rath, P. Walter, S. Tajima, 1986, The Journal of cell biology.

The beta subunit of the signal recognition particle receptor is a transmembrane GTPase that anchors the alpha subunit, a peripheral membrane GTPase, to the endoplasmic reticulum membrane

P. Walter, S. Tajima, J. Miller, 1995, The Journal of cell biology.

Acquisition of Secretion of Transforming Growth Factor-β1 Leads to Autonomous Suppression of Scavenger Receptor Activity in a Monocyte-Macrophage Cell Line, THP-1*

M. Harada‐Shiba, S. Tajima, A. Yamamoto, 1998, The Journal of Biological Chemistry.

Synthesis of histone proteins by CPE ligation using a recombinant peptide as the C-terminal building block.

T. Kawakami, I. Suetake, S. Tajima, 2015, Journal of biochemistry.

Structural insight into maintenance methylation by mouse DNA methyltransferase 1

E. Yamashita, A. Nakagawa, I. Suetake, 2011 .

NMR Characterization of the Interaction of the Endonuclease Domain of MutL with Divalent Metal Ions and ATP

N. Kamiya, K. Fukui, Y. Takano, 2014, PloS one.

Risk Factors for Atherosclerotic Vascular Diseases with Special Reference to the Relationship between Apolipoprotein E Mutations and Hyperlipidemia

S. Tajima, A. Yamamoto, T. Yamamura, 1990, Annals of the New York Academy of Sciences.

miRNA-720 Controls Stem Cell Phenotype, Proliferation and Differentiation of Human Dental Pulp Cells

M. Takigawa, E. S. Hara, S. Calderwood, 2013, PloS one.

The role of phosphorylation of histone H3 at serine 10 in chromatin condensation in vitro

K. Fukui, S. Uchiyama, Takayuki Kato, 2015 .

Synaptic control of DNA-methylation involves activity-dependent degradation of DNMT3a1 in the nucleus

M. Kreutz, O. Stork, S. Tajima, 2019, bioRxiv.

Domain Structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA Methyltransferases.

A. Nakagawa, Jikui Song, I. Suetake, 2022, Advances in experimental medicine and biology.

Genome-Wide Analysis of DNA Methylation and Expression of MicroRNAs in Breast Cancer Cells

K. Nakai, R. Yamashita, A. Fujiyama, 2012, International journal of molecular sciences.

Evaluation of pH-responsive liposomes containing amino acid-based zwitterionic lipids for improving intracellular drug delivery in vitro and in vivo.

Shoji Tajima, S. Takeoka, S. Tajima, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Deletion of the Growth Factor Homology Domain of the Low Density Lipoprotein Receptor in Familial Hypercholesterolemia

T. Funahashi, S. Tajima, A. Yamamoto, 1990 .

Xenopus eggs express an identical DNA methyltransferase, Dnmt1, to somatic cells.

T. Kawakami, I. Suetake, S. Tajima, 2001, Journal of Biochemistry (Tokyo).

Array-based genomic resequencing of human leukemia

T. Naoe, A. Iwama, M. Toyota, 2010, Oncogene.

The fl Subunit of the Signal Recognition Particle Receptor Is a Transmembrane GTPase that Anchors the a Subunit, a Peripheral Membrane GTPase, to the Endoplasmic Reticulum Membrane

P. Walter, S. Tajima, L. Lauffer, 2002 .

Synaptic control of DNA methylation involves activity-dependent degradation of DNMT3A1 in the nucleus

M. Kreutz, O. Stork, A. Karpova, 2020, Neuropsychopharmacology.

Overexpression of DNA methyltransferase in myoblast cells accelerates myotube formation.

S. Tajima, A. Asano, Hidekazu Takagi, 1995, European journal of biochemistry.

Selective oxidation of 5-hydroxymethylcytosine with micelle incarcerated oxidants to determine it at single base resolution.

I. Suetake, S. Tajima, K. Tachibana, 2015, Bioorganic & medicinal chemistry letters.