M. Ma

发表

Quantitative profiling of initiating ribosomes in vivo

Shu-Bing Qian, Ji Wan, Botao Liu, 2014, Nature Methods.

A proteogenomics approach integrating proteomics and ribosome profiling increases the efficiency of protein identification and enables the discovery of alternative translation start sites

B. Shen, K. Gevaert, W. Van Criekinge, 2014, Proteomics.

Crystal Structure of SgcJ, An NTF2-Like Superfamily Protein Involved in Biosynthesis of the 9-Membered Enediyne Antitumor Antibiotic C-1027

B. Shen, G. Phillips, A. Joachimiak, 2016, The Journal of Antibiotics.

Structure of the ent-Copalyl Diphosphate Synthase PtmT2 from Streptomyces platensis CB00739, a Bacterial Type II Diterpene Synthase

B. Shen, G. Phillips, A. Joachimiak, 2016, Journal of the American Chemical Society.

Functional characterization and structural basis of an efficient di-C-glycosyltransferase from Glycyrrhiza glabra.

C. Yun, Zhen-ming Liu, M. Ma, 2020, Journal of the American Chemical Society.

Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus

B. Shen, G. Phillips, A. Joachimiak, 2016, Biochemistry.

The crystal structure of BlmI as a model for nonribosomal peptide synthetase peptidyl carrier proteins

B. Shen, G. Phillips, A. Joachimiak, 2014, Proteins.

Leinamycin E1 acting as an anticancer prodrug activated by reactive oxygen species

B. Shen, G. Wilding, D. Church, 2015, Proceedings of the National Academy of Sciences.

A Long-Range Acting Dehydratase Domain as the Missing Link for C17-Dehydration in Iso-Migrastatin Biosynthesis.

B. Shen, Bo Zhang, M. Ma, 2017, Angewandte Chemie.

Post-polyketide synthase steps in iso-migrastatin biosynthesis, featuring tailoring enzymes with broad substrate specificity.

B. Shen, M. Ma, J. Ju, 2013, Journal of the American Chemical Society.

Cycloheximide and Actiphenol Production in Streptomyces sp. YIM56141 Governed by Single Biosynthetic Machinery Featuring an Acyltransferase-less Type I Polyketide Synthase

B. Shen, M. Ma, Li-hua Xu, 2014, Organic letters.

Discovery and Biosynthesis of Pepticinnamins G-M Featuring Three Enzymes-Catalyzed Nonproteinogenic Amino Acid Formation.

Tongtong Geng, M. Ma, Y. Ge, 2020, The Journal of organic chemistry.

Strepimidazoles A-G from the Plant Endophytic Streptomyces sp. PKU-EA00015 with Inhibitory Activities against a Plant Pathogenic Fungus.

Lanping Guo, M. Ma, Yuquan Xu, 2020, Journal of natural products.

Flavin-enabled reductive and oxidative epoxide ring opening reactions

Hung‐wen Liu, A. Mándi, T. Kurtán, 2022, Nature Communications.

Crystal Structure of the Zorbamycin-Binding Protein ZbmA, the Primary Self-Resistance Element in Streptomyces flavoviridis ATCC21892.

B. Shen, G. Phillips, A. Joachimiak, 2015, Biochemistry.

Decoding Human Cytomegalovirus

Marco Y. Hein, Nicholas T. Ingolia, B. Shen, 2012, Science.

Nonspecific Heme-Binding Cyclase, AbmU, Catalyzes [4 + 2] Cycloaddition during Neoabyssomicin Biosynthesis

M. Ma, J. Ju, Hongbo Huang, 2020, ACS omega.

Discovery of a Phenylamine-Incorporated Angucyclinone from Marine Streptomyces sp. PKU-MA00218 and Generation of Derivatives with Phenylamine Analogues.

Tongtong Geng, Youming Zhang, M. Ma, 2019, Organic letters.

Structural and evolutionary relationships of “AT-less” type I polyketide synthase ketosynthases

B. Shen, G. Phillips, A. Joachimiak, 2015, Proceedings of the National Academy of Sciences.

Germicidins H–J from Streptomyces sp. CB00361

B. Shen, M. Rateb, M. Ma, 2016, The Journal of Antibiotics.

Biochemical characterization of a novel bifunctional glycosyl-1-phosphate transferase involved in the exopolysaccharide biosynthesis.

R. Jiang, M. Ma, Yuan Li, 2015, Biochemical and biophysical research communications.

Functional characterization and structural bases of two class I diterpene synthases in pimarane-type diterpene biosynthesis

Juan Guo, Luqi Huang, M. Ma, 2021, Communications Chemistry.

Discovery of cyclohexadepsipeptides with anti-Zika virus activities and biosynthesis of the nonproteinogenic building block (3S)-methyl-l-proline

Dong Liu, Wenhan Lin, M. Ma, 2021, The Journal of biological chemistry.

Crystal Structures of Fsa2 and Phm7 Catalyzing [4 + 2] Cycloaddition Reactions with Reverse Stereoselectivities in Equisetin and Phomasetin Biosynthesis

Hongwei Jin, Huan Zhou, M. Ma, 2021, ACS omega.

Discovery of the leinamycin family of natural products by mining actinobacterial genomes

B. Shen, J. Suh, F. van Nieuwerburgh, 2017, Proceedings of the National Academy of Sciences.

Glycopeptide Self-Assembly Modulated by Glycan Stereochemistry through Glycan-Aromatic Interactions.

Weilin Zhang, M. Ma, S. Dong, 2020, Journal of the American Chemical Society.

C-S bond cleavage by a polyketide synthase domain

B. Shen, M. Ma, J. Lohman, 2015, Proceedings of the National Academy of Sciences.

Functional Characterization and Crystal Structure of the Bifunctional Thioesterase Catalyzing Epimerization and Cyclization in Skyllamycin Biosynthesis

Tongtong Geng, Hongwei Jin, L. Zhang, 2021, ACS Catalysis.

P450-Catalyzed Tailoring Steps in Leinamycin Biosynthesis Featuring Regio- and Stereoselective Hydroxylations and Substrate Promiscuities.

B. Shen, J. Cleveland, M. Ma, 2018, Biochemistry.

Synthesis and evaluation of 8,4'-dideshydroxy-leinamycin revealing new insights into the structure-activity relationship of the anticancer natural product leinamycin.

B. Shen, J. Cleveland, M. Ma, 2015, Bioorganic & medicinal chemistry letters.

Comparative Characterization of the Lactimidomycin and iso-Migrastatin Biosynthetic Machineries Revealing Unusual Features for Acyltransferase-less Type I Polyketide Synthases and Providing an Opportunity To Engineer New Analogues

B. Shen, Hui Jiang, J. Cleveland, 2014, Biochemistry.

Piperazine ring formation by a single-module NRPS and cleavage by an α-KG-dependent nonheme iron dioxygenase in brasiliamide biosynthesis

Dong Liu, Wenhan Lin, M. Ma, 2020, Applied Microbiology and Biotechnology.

Functional Characterization and Crystal Structure of the Type II Peptidyl Carrier Protein ColA1a in Collismycins Biosynthesis †

M. Ma, Wen Liu, Xueyan Ma, 2020 .

Fluostatins M–Q Featuring a 6-5-6-6 Ring Skeleton and High Oxidized A-Rings from Marine Streptomyces sp. PKU-MA00045

Wei Cheng, Dong Liu, M. Ma, 2018, Marine drugs.

Cytochromes P450 for natural product biosynthesis in Streptomyces: sequence, structure, and function.

B. Shen, M. Ma, J. Rudolf, 2017, Natural product reports.

Angucyclines and Angucyclinones from Streptomyces sp. CB01913 Featuring C-Ring Cleavage and Expansion.

B. Shen, M. Rateb, M. Ma, 2015, Journal of natural products.

Biosynthetic Potential-Based Strain Prioritization for Natural Product Discovery: A Showcase for Diterpenoid-Producing Actinomycetes

Yijun Yan, Ming Ma, Ben Shen, 2014, Journal of natural products.

Deciphering Poxvirus Gene Expression by RNA Sequencing and Ribosome Profiling

B. Moss, Zhi Xie, S. Porcella, 2015, Journal of Virology.

Bacillibactin and Bacillomycin Analogues with Cytotoxicities against Human Cancer Cell Lines from Marine Bacillus sp. PKU-MA00093 and PKU-MA00092

Dong Liu, M. Ma, Ying-tao Zhang, 2018, Marine drugs.

A DasA family sugar binding protein Ste2 links nutrient and oxidative stress to exopolysaccharides production in Streptomyces sp. 139

M. Ma, Guangzhi Shan, Mengxin Geng, 2022, BMC microbiology.

Dihydrofolate reductase-like protein inactivates hemiaminal pharmacophore for self-resistance in safracin biosynthesis

Y. Zhang, M. Ma, G. Tang, 2022, Acta pharmaceutica Sinica. B.

Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications

M. Ma, Zhengdong Wang, Wen Zhang, 2021, Chemical science.

Biochemical and Structural Characterization of TtnD, a Prenylated FMN-Dependent Decarboxylase from the Tautomycetin Biosynthetic Pathway.

Mitchell D. Miller, B. Shen, G. Phillips, 2018, ACS chemical biology.

Crystal Structure Based Mutagenesis of Cattleyene Synthase Leads to the Generation of Rearranged Polycyclic Diterpenes

Jeroen S. Dickschat, M. Ma, Zhengren Xu, 2022, Angewandte Chemie.

Enzymatic Synthesis of a Diastereomer of Neoabyssomicin Derivative Using the Diels‐Alderase AbyU

Xiaoyi Wei, M. Ma, J. Ju, 2021 .

Structural Insights into Three Sesquiterpene Synthases for the Biosynthesis of Tricyclic Sesquiterpenes and Chemical Space Expansion by Structure-Based Mutagenesis.

Jeroen S. Dickschat, Ruibo Wu, M. Ma, 2023, Journal of the American Chemical Society.

Structure-Based Mechanistic Insights into ColB1, a Flavoprotein Functioning in-trans in the 2,2'-Bipyridine Assembly Line for Cysteine Dehydrogenation.

M. Ma, Wen Liu, Wenping Ding, 2023, ACS chemical biology.