J. Fisher

发表

ECOSYSTEM PLANNING FOR CANADIAN URBAN REGIONS

Robert B. Gibson, Ray Tomalty, D. Alexander, 1994 .

Inhibition of histone deacetylases: a pharmacological approach to the treatment of non-cancer disorders.

O. Wiest, P. Helquist, J. Fisher, 2009, Current topics in medicinal chemistry.

Endless Resistance. Endless Antibiotics?

S. Mobashery, J. Fisher, 2016, MedChemComm.

Constructing and deconstructing the bacterial cell wall

S. Mobashery, J. Fisher, 2019, Protein science : a publication of the Protein Society.

Molecular Basis and Phenotype of Methicillin Resistance in Staphylococcus aureus and Insights into New β-Lactams That Meet the Challenge

S. Mobashery, J. Fisher, Leticia I. Llarrull, 2009, Antimicrobial Agents and Chemotherapy.

8.13 – Enzymology of Bacterial Resistance

S. Mobashery, J. Fisher, 2010 .

Recent advances in MMP inhibitor design

S. Mobashery, J. Fisher, Shahriar Mobashery, 2006, Cancer and Metastasis Reviews.

A convenient synthesis of 7α-hydroxycholest-4-en-3-one by the hydroxypropyl-β-cyclodextrin-facilitated cholesterol oxidase oxidation of 3β,7α-cholest-5-ene-3,7-diol

J. Fisher, D. L. Alexander, 1995, Steroids.

Chemical studies on the inactivation of Escherichia coli RTEM beta-lactamase by clavulanic acid.

J. Knowles, J. Fisher, R. Charnas, 1978, Biochemistry.

β-Lactam Antibiotics

S. Mobashery, J. Fisher, S. Testero, 2010 .

Penicillin-Binding Protein 5 of Escherichia coli

Malika Kumarasiri, S. Mobashery, J. Fisher, 2013 .

Structural Analysis of the Role of Pseudomonas aeruginosa Penicillin-Binding Protein 5 in β-Lactam Resistance

Malika Kumarasiri, S. Mobashery, M. Tóth, 2013, Antimicrobial Agents and Chemotherapy.

Investigation of the mechanism of the cell wall DD-carboxypeptidase reaction of penicillin-binding protein 5 of Escherichia coli by quantum mechanics/molecular mechanics calculations.

Samy O Meroueh, S. Meroueh, S. Mobashery, 2008, Journal of the American Chemical Society.

Catalytic Cycle of Glycoside Hydrolase BglX from Pseudomonas aeruginosa and Its Implication in Biofilm Formation.

J. Hermoso, Kiran V. Mahasenan, S. Mobashery, 2019, ACS chemical biology.

Conformational Dynamics in Penicillin-Binding Protein 2a of Methicillin-Resistant Staphylococcus aureus, Allosteric Communication Network and Enablement of Catalysis.

R. Molina, J. Hermoso, Kiran V. Mahasenan, 2017, Journal of the American Chemical Society.

Three-dimensional QSAR analysis and design of new 1,2,4-oxadiazole antibacterials.

Malika Kumarasiri, Kiran V. Mahasenan, S. Mobashery, 2016, Bioorganic & medicinal chemistry letters.

A convenient synthesis of 7 alpha-hydroxycholest-4-en-3-one by the hydroxypropyl-beta-cyclodextrin-facilitated cholesterol oxidase oxidation of 3 beta,7 alpha-cholest-5-ene-3,7-diol.

J. Fisher, D. L. Alexander, 1995, Steroids.

The β-Lactam Antibiotics: Their Future in the Face of Resistance

S. Mobashery, J. Fisher, Erika Leemans, 2014 .

Appraisal of a glycopeptide cloaking strategy for a therapeutic oligopeptide: glycopeptide analogs of the renin inhibitor ditekiren.

J. Fisher, A. Harrison, M. Williams, 1994, Bioorganic & medicinal chemistry.

Allosteric Inhibition of Bacterial Targets: An Opportunity for Discovery of Novel Antibacterial Classes

S. Mobashery, J. Fisher, Mayland Chang, 2017 .

Muropeptide Binding and the X-ray Structure of the Effector Domain of the Transcriptional Regulator AmpR of Pseudomonas aeruginosa.

David A. Dik, L. Hellman, J. Hermoso, 2017, Journal of the American Chemical Society.

2007 Foundation Host-Guest Chemistry of the Peptidoglycan

S. Mobashery, J. Fisher, 2011 .

Metabolism of the Selective Matrix Metalloproteinase-9 Inhibitor (R)-ND-336.

S. Mobashery, J. Fisher, Mayland Chang, 2021, ACS pharmacology & translational science.

Reconstitution of flavin enzymes with 1-carba-1 -deazaflavin coenzyme analogues.

C. Walsh, J. Fisher, R. Spencer, 1977, Biochemistry.

Enzyme-catalyzed redox reactions with the flavin analogues 5-deazariboflavin, 5-deazariboflavin 5'-phosphte, and 5-deazariboflavin 5'-diphosphate, 5' leads to 5'-adenosine ester.

C. Walsh, J. Fisher, R. Spencer, 1976, Biochemistry.

Method for measuring the activities of cholesteryl ester transfer protein (lipid transfer protein).

R. Ulrich, D. Epps, J. Fisher, 1995, Chemistry and physics of lipids.

Peptidomimetic Inhibitors of Human Immunodeficiency Virus Protease ( HIV‐PR): Design, Enzyme Binding and Selectivity, Antiviral Efficacy, and Cell Permeability Properties.

D. Decamp, C. Craik, W. Lowther, 1995 .

Inactivation of the RTEM beta-lactamase from Escherichia coli. Interaction of penam sulfones with enzyme.

J. Knowles, J. Fisher, R. Charnas, 1981, Biochemistry.

Synthesis and NMR characterization of (Z,Z,Z,Z,E,E,ω)-heptaprenol.

J. Zajicek, S. Mobashery, J. Fisher, 2012, Journal of the American Chemical Society.

β-Lactam Resistance Mechanisms: Gram-Positive Bacteria and Mycobacterium tuberculosis.

S. Mobashery, J. Fisher, 2016, Cold Spring Harbor perspectives in medicine.

Chapter 25. Bacterial Resistance to β-Lactams: The β-Lactamases

J. Fisher, Jeremy R. Knowles, 1978 .

Peptide to glycopeptide: glycosylated oligopeptide renin inhibitors with attenuated in vivo clearance properties.

J. Fisher, B. Rush, A. Harrison, 1991, Journal of medicinal chemistry.

b -Lactam Resistance Mechanisms: Gram-Positive Bacteria and Mycobacterium tuberculosis

S. Mobashery, J. Fisher, 2016 .

From Genome to Proteome to Elucidation of Reactions for All Eleven Known Lytic Transglycosylases from Pseudomonas aeruginosa.

David A. Dik, S. Mobashery, J. Fisher, 2017, Angewandte Chemie.

Catalytic Spectrum of the Penicillin-Binding Protein 4 of Pseudomonas aeruginosa, a Nexus for the Induction of β-Lactam Antibiotic Resistance

S. Mobashery, J. Fisher, Mijoon Lee, 2014, Journal of the American Chemical Society.

Fluorescence Assessment of the AmpR-Signaling Network of Pseudomonas aeruginosa to Exposure to β-Lactam Antibiotics.

David A. Dik, S. Mobashery, Choonkeun Kim, 2020, ACS chemical biology.

Development of an Immunoassay for Endogenous Digitalislike Factor

J. Fisher, J. Hamlyn, D. Ducharme, 1991, Hypertension.

Active Site Ring‐Opening of a Thiirane Moiety and Picomolar Inhibition of Gelatinases

R. Fridman, S. Mobashery, Michael Gossing, 2009, Chemical biology & drug design.

Exploration of mild copper-mediated coupling of organotrifluoroborates in the synthesis of thiirane-based inhibitors of matrix metalloproteinases.

S. Mobashery, J. Fisher, R. Bouley, 2011, Bioorganic & medicinal chemistry letters.

Bacterial Resistance to β‐Lactam Antibiotics: Compelling Opportunism, Compelling Opportunity

S. Meroueh, S. Mobashery, J. Fisher, 2005 .

Chemical and enzymic properties of riboflavin analogs

C. Walsh, J. Fisher, W. Ashton, 1978 .

Chemical and enzymatic properties of riboflavin analogues.

C. Walsh, R. Brown, J. Fisher, 1978, Biochemistry.

One-and two-electron redox chemistry of 1-carba-1-deazariboflavin.

C. Walsh, J. Fisher, R. Spencer, 1977, Biochemistry.

Preparation, characterization, and chemical properties of the flavin coenzyme analogues 5-deazariboflavin, 5-deazariboflavin 5'-phosphate, and 5-deazariboflavin 5'-diphosphate, 5' → 5'-adenosine ester

C. Walsh, J. Fisher, R. Spencer, 1976 .

Conformational analyses of thiirane-based gelatinase inhibitors.

S. Mobashery, J. Fisher, Mijoon Lee, 2008, Bioorganic & medicinal chemistry letters.

The future of the β-lactams.

S. Mobashery, J. Fisher, S. Testero, 2010, Current opinion in microbiology.

The future of the b-lactams

S. Mobashery, J. Fisher, S. Testero, 2010 .

Stereoselectivity of chloroperoxidase-dependent halogenation.

J. Fisher, M. Oppenhuizen, K. Ramakrishnan, 1983, Biochemistry.

Activation by Allostery in Cell-Wall Remodeling by a Modular Membrane-Bound Lytic Transglycosylase from Pseudomonas aeruginosa.

David A. Dik, J. Hermoso, Kiran V. Mahasenan, 2016, Structure.

Total Syntheses of Bulgecins A, B, and C and Their Bactericidal Potentiation of the β-Lactam Antibiotics

David A. Dik, S. Mobashery, J. Fisher, 2018, ACS infectious diseases.

In vitro studies of the protein-interaction network of cell-wall lytic transglycosylase RlpA of Pseudomonas aeruginosa

S. Mobashery, Choonkeun Kim, J. Fisher, 2022, Communications Biology.

Beta-lactamase inactivation by mechanism-based reagents.

J. Belasco, J. Fisher, J. Knowles, 1980, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Ensemble of Pinanones from the Permanganate Oxidation of Myrtenal.

A. Oliver, J. Fisher, Mijoon Lee, 2016, The Journal of organic chemistry.

Use of silver carbonate in the Wittig reaction.

S. Mobashery, J. Fisher, Mijoon Lee, 2013, The Journal of organic chemistry.

Medicinal Chemistry of β‐Lactam Antibiotics

S. Mobashery, J. Fisher, S. Testero, 2021 .

Bacterial resistance to beta-lactam antibiotics: compelling opportunism, compelling opportunity.

Samy O Meroueh, S. Meroueh, S. Mobashery, 2005, Chemical reviews.

β-Lactams against the Fortress of the Gram-Positive Staphylococcus aureus Bacterium.

S. Mobashery, J. Fisher, 2020, Chemical reviews.

Messenger functions of the bacterial cell wall-derived muropeptides.

S. Mobashery, J. Fisher, M. Boudreau, 2012, Biochemistry.

Direct enzyme-catalyzed reduction of anthracyclines by reduced nicotinamide adenine dinucleotide.

J. Fisher, J. Becvar, K. Ramakrishnan, 1983, Biochemistry.

Reductive drug metabolism.

J. Fisher, K. E. Mclane, K. Ramakrishnan, 1983, Drug metabolism reviews.

Complexation of anthracycline antibiotics by the apo egg white riboflavin binding protein.

J. Fisher, K. E. Mclane, K. Ramakrishnan, 1982, Biochemistry.

Inhibitors for Bacterial Cell-Wall Recycling.

A. Oliver, S. Mobashery, J. Fisher, 2012, ACS medicinal chemistry letters.

Synthesis and shift-reagent-assisted full NMR assignment of bacterial (Z8,E2,ω)-undecaprenol.

J. Zajicek, S. Mobashery, J. Fisher, 2017, Chemical communications.

Discrete steps in sensing of beta-lactam antibiotics by the BlaR1 protein of the methicillin-resistant Staphylococcus aureus bacterium.

C. Wharton, S. Mobashery, J. Fisher, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Reduction of estradiol 3-methyl ether by lithium and gaseous ammonia.

J. Fisher, L. Smith, 1967, Steroids.

Cell-Wall Recycling of the Gram-Negative Bacteria and the Nexus to Antibiotic Resistance.

David A. Dik, S. Mobashery, J. Fisher, 2018, Chemical reviews.

Evaluation of a vitamin-cloaking strategy for oligopeptide therapeutics: biotinylated HIV-1 protease inhibitors.

R. Borchardt, J. Fisher, K. Ng, 1994, Journal of medicinal chemistry.

Epidemiological expansion, structural studies, and clinical challenges of new β-lactamases from gram-negative bacteria.

K. Bush, J. Fisher, Jed F Fisher, 2011, Annual review of microbiology.

Antibacterials: Volume II

S. Mobashery, J. Fisher, Marvin J. Miller, 2018 .

Bacterial cell‐wall recycling

S. Mobashery, J. Fisher, Jed F Fisher, 2013, Annals of the New York Academy of Sciences.

Three-dimensional structure of the bacterial cell wall peptidoglycan.

S. Meroueh, T. Stemmler, S. Mobashery, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Enzymatic reduction of 5-deazariboflavine from reduced nicotinamide adenine dinucleotide by direct hydrogen transfer.

C. Walsh, J. Fisher, 1974, Journal of the American Chemical Society.

ENCYMATIC REDUCTION OF 5-DEAZARIBOFLAVINE FROM REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE BY DIRECT HYDROGEN TRANSFER

C. Walsh, J. Fisher, 1974 .

Integrative structural biology of the penicillin-binding protein-1 from Staphylococcus aureus, an essential component of the divisome machinery

I. Muñoz, R. Molina, J. Hermoso, 2021, Computational and structural biotechnology journal.

Chemical studies on the inactivation of Escherichia coli RTEM β-lactamase by clavulanic acid

J. Knowles, J. Fisher, R. Charnas, 1978 .

Kinetic studies on the inactivation of Escherichia coli RTEM beta-lactamase by clavulanic acid.

J. Knowles, J. Fisher, R. Charnas, 1978, Biochemistry.

β-Lactam resistance in Staphylococcus aureus: the adaptive resistance of a plastic genome

S. Mobashery, J. Fisher, C. Fuda, 2005, Cellular and Molecular Life Sciences.

The sentinel role of peptidoglycan recycling in the β-lactam resistance of the Gram-negative Enterobacteriaceae and Pseudomonas aeruginosa.

S. Mobashery, J. Fisher, 2014, Bioorganic chemistry.

Strategies for Circumventing Bacterial Resistance Mechanisms

S. Mobashery, J. Fisher, J. Johnson, 2014 .

beta-Lactamase proceeds via an acyl-enzyme intermediate. Interaction of the Escherichia coli RTEM enzyme with cefoxitin.

J. Knowles, J. Belasco, J. Fisher, 1980, Biochemistry.

Acquired Class D β-Lactamases

J. Fisher, N. T. Antunes, 2014, Antibiotics.

The bifunctional enzymes of antibiotic resistance.

S. Mobashery, J. Fisher, Weilie Zhang, 2009, Current opinion in microbiology.

Lytic transglycosylases: concinnity in concision of the bacterial cell wall

David A. Dik, S. Mobashery, J. Fisher, 2017, Critical reviews in biochemistry and molecular biology.

CHAPTER 2 – β-Lactams Resistant to Hydrolysis by the β-Lactamases

J. Fisher, 1984 .

Protonation states of active‐site lysines of penicillin‐binding protein 6 from Escherichia coli and the mechanistic implications

Malika Kumarasiri, S. Mobashery, J. Fisher, 2014, Proteins.

How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function

J. Hermoso, Malika Kumarasiri, C. Carrasco-López, 2013, Proceedings of the National Academy of Sciences.

Structure-Activity Relationship for the Picolinamide Antibacterials that Selectively Target Clostridioides difficile.

A. Oliver, S. Mobashery, J. Fisher, 2021, ACS medicinal chemistry letters.

Mechanism-based profiling of MMPs.

S. Mobashery, J. Fisher, 2010, Methods in molecular biology.

β-Lactams from the Ocean

S. Mobashery, J. Fisher, 2023, Marine drugs.

7-Deoxydaunomycinone quinone methide reactivity with thiol nucleophiles.

J. Fisher, K. Ramakrishnan, 1986, Journal of medicinal chemistry.

13 Bacterial Cell Wall Morphology and Biochemistry

S. Mobashery, J. Fisher, M. Suvorov, 2009 .

Bacterial Cell Wall

S. Mobashery, J. Fisher, 2015 .

Nanomolecular and Supramolecular Paths toward Peptidoglycan Structure

S. Meroueh, S. Mobashery, J. Fisher, 2006 .

Slt, MltD, and MltG of Pseudomonas aeruginosa as Targets of Bulgecin A in Potentiation of β-Lactam Antibiotics.

David A. Dik, W. Boggess, S. Mobashery, 2019, ACS chemical biology.

Structure and Cell Wall Cleavage by Modular Lytic Transglycosylase MltC of Escherichia coli

J. Hermoso, Hualiang Pi, Kiran V. Mahasenan, 2014, ACS chemical biology.

Three Decades of the Class A β-Lactamase Acyl-Enzyme

S. Mobashery, J. Fisher, Shahriar Mobashery, 2009 .

The Natural Occurrence of Ethionine in Bacteria

J. Fisher, M. F. Mallette, 1961, The Journal of general physiology.

Regioselective Control of the SNAr Amination of 5-Substituted-2,4-Dichloropyrimidines Using Tertiary Amine Nucleophiles.

A. Oliver, S. Mobashery, J. Fisher, 2015, The Journal of organic chemistry.

Regioselective Control of the SNAr Amination of 5‐Substituted‐2,4‐dichloropyrimidines Using Tertiary Amine Nucleophiles.

A. Oliver, S. Mobashery, J. Fisher, 2015 .

Antibacterials: Volume I

S. Mobashery, R. Melander, C. Melander, 2018 .

Evaluation of the bile acid transporter in enhancing intestinal permeability to renin-inhibitory peptides.

I. Hidalgo, R. Borchardt, J. Fisher, 1993, Journal of drug targeting.

The Tipper-Strominger Hypothesis and Triggering of Allostery in Penicillin-Binding Protein 2a of Methicillin-Resistant Staphylococcus aureus (MRSA).

S. Mobashery, J. Fisher, Mayland Chang, 2015, Journal of the American Chemical Society.

Unusual steroid specificity of the cell surface progesterone receptor on human sperm.

P. Blackmore, J. Fisher, C. Spilman, 1996, Molecular pharmacology.

A computational evaluation of the mechanism of penicillin-binding protein-catalyzed cross-linking of the bacterial cell wall.

S. Meroueh, S. Mobashery, J. Fisher, 2011, Journal of the American Chemical Society.

Discovery of a potent picolinamide antibacterial active against Clostridioides difficile.

S. Mobashery, J. Fisher, E. Lastochkin, 2020, ACS infectious diseases.

Cinnamonitrile Adjuvants Restore Susceptibility to β-Lactams against Methicillin-Resistant Staphylococcus aureus.

S. Mobashery, Choonkeun Kim, J. Fisher, 2019, ACS medicinal chemistry letters.

Ab initio QM/MM study of class A beta-lactamase acylation: dual participation of Glu166 and Lys73 in a concerted base promotion of Ser70.

Samy O Meroueh, H. Schlegel, S. Meroueh, 2005, Journal of the American Chemical Society.

Three decades of the class A beta-lactamase acyl-enzyme.

S. Mobashery, J. Fisher, Jed F Fisher, 2009, Current protein & peptide science.

Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques

R. Russell, B. Testa, S. Prior, 1988, Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques.

Mechanism of the Escherichia coli MltE lytic transglycosylase, the cell-wall-penetrating enzyme for Type VI secretion system assembly

David A. Dik, J. Hermoso, Malika Kumarasiri, 2018, Scientific Reports.

Dimerization and activation of porcine pancreatic phospholipase A2 via substrate level acylation of lysine 56.

A. Tomasselli, I. Reardon, R. Heinrikson, 1989, The Journal of biological chemistry.

Matrix metalloproteinase 2 inhibition: combined quantum mechanics and molecular mechanics studies of the inhibition mechanism of (4-phenoxyphenylsulfonyl)methylthiirane and its oxirane analogue.

Thom Vreven, Peng Tao, H. Schlegel, 2009, Biochemistry.

Tautomeric instability of 10-deoxydaunomycinone hydroquinone

J. Fisher, D. Brand, 1986 .

Spectral characterization of environment-sensitive adducts of interleukin-1 beta.

D. Epps, J. Paslay, J. Fisher, 1992, The Journal of biological chemistry.

Kinetics and inhibition of lipid exchange catalyzed by plasma cholesteryl ester transfer protein (lipid transfer protein).

D. Epps, J. Fisher, E. Thomas, 1995, Biochemistry.

Bacterial Cell Wall: Morphology and Biochemistry

S. Mobashery, J. Fisher, Stefania De Benedetti, 2022, Practical Handbook of Microbiology.

Peptidomimetic inhibitors of human immunodeficiency virus protease (HIV-PR): Design, enzyme binding and selectivity, antiviral efficacy, and cell permeability properties

D. Decamp, C. Craik, W. Lowther, 1993 .

Molecular structures and dynamics of the stepwise activation mechanism of a matrix metalloproteinase zymogen: challenging the cysteine switch dogma.

S. Meroueh, R. Fridman, S. Mobashery, 2007, Journal of the American Chemical Society.

Host-guest chemistry of the peptidoglycan.

S. Mobashery, J. Fisher, 2010, Journal of medicinal chemistry.

Exploration of mild copper-mediated coupling of organotrifluoroborates in the synthesis of thiirane-based inhibitors of matrix metalloproteinases.

S. Mobashery, J. Fisher, R. Bouley, 2011, Bioorganic & medicinal chemistry letters.

Elucidation of the structure of the membrane anchor of penicillin-binding protein 5 of Escherichia coli.

J. Zajicek, S. Mobashery, J. Fisher, 2010, Journal of the American Chemical Society.

Three-dimensional QSAR analysis and design of new 1,2,4-oxadiazole antibacterials.

Malika Kumarasiri, Kiran V. Mahasenan, S. Mobashery, 2016, Bioorganic & medicinal chemistry letters.

Matrix metalloproteinase 2 (MMP2) inhibition: DFT and QM/MM studies of the deprotonation-initialized ring-opening reaction of the sulfoxide analogue of SB-3CT.

Peng Tao, H. Schlegel, Peng Tao, 2010, The journal of physical chemistry. B.

Amber‐codon suppression for spatial localization and in vivo photoaffinity capture of the interactome of the Pseudomonas aeruginosa rare lipoprotein A lytic transglycosylase

S. Mobashery, J. Fisher, Luis F. Avila-Cobian, 2023, Protein science : a publication of the Protein Society.

Lytic transglycosylases: concinnity in concision of the bacterial cell wall

David A. Dik, S. Mobashery, J. Fisher, 2017, Critical reviews in biochemistry and molecular biology.

A Structural Dissection of the Active Site of the Lytic Transglycosylase MltE from Escherichia coli.

David A. Dik, J. Hermoso, Kiran V. Mahasenan, 2018, Biochemistry.

Muropeptide Binding and the X-ray Structure of the Effector Domain of the Transcriptional Regulator AmpR of Pseudomonas aeruginosa.

David A. Dik, L. Hellman, J. Hermoso, 2017, Journal of the American Chemical Society.

Catalytic process of anhydro-N-acetylmuramic acid kinase from Pseudomonas aeruginosa

J. Hermoso, S. Mobashery, J. Fisher, 2023, The Journal of biological chemistry.

β-Lactams from the Ocean

S. Mobashery, J. Fisher, 2023, Marine drugs.

The Tipper-Strominger Hypothesis and Triggering of Allostery in Penicillin-Binding Protein 2a of Methicillin-Resistant Staphylococcus aureus (MRSA).

S. Mobashery, J. Fisher, Mayland Chang, 2015, Journal of the American Chemical Society.

The mechanism of adduct formation between reduced flavins and arene epoxides

J. Fisher, Y. T. Lee, 1993 .