V. Galkin

发表

Actin Filaments as Tension Sensors

E. Egelman, V. Galkin, A. Orlova, 2012, Current Biology.

Opening of tandem calponin homology domains regulates their affinity for F-actin

E. Egelman, K. Djinović-Carugo, V. Galkin, 2010, Nature Structural &Molecular Biology.

ParA2, a Vibrio cholerae chromosome partitioning protein, forms left-handed helical filaments on DNA

M. Waldor, E. Egelman, Xiong Yu, 2010, Proceedings of the National Academy of Sciences.

PLATFORM O: Actin & Actin-binding Proteins

Feng Liu, T. Shibata, E. Egelman, 2011 .

Actin Depolymerizing Factor Stabilizes an Existing State of F-Actin and Can Change the Tilt of F-Actin Subunits

Willy Wriggers, Edward H. Egelman, Vitold E. Galkin, 2001, The Journal of cell biology.

Mapping of drebrin binding site on F-actin.

E. Egelman, A. Ytterberg, J. Loo, 2010, Journal of molecular biology.

High-resolution cryo-EM structure of the F-actin–fimbrin/plastin ABD2 complex

E. Egelman, V. Galkin, A. Orlova, 2008, Proceedings of the National Academy of Sciences.

Coronin-1A stabilizes F-actin by bridging adjacent actin protomers and stapling opposite strands of the actin filament.

H. Kueh, T. Mitchison, E. Egelman, 2008, Journal of molecular biology.

Xin-repeats and nebulin-like repeats bind to F-actin in a similar manner.

E. Egelman, P. F. van der Ven, D. Fürst, 2006, Journal of molecular biology.

Actin-destabilizing factors disrupt filaments by means of a time reversal of polymerization.

E. Egelman, V. Galkin, A. Orlova, 2004, Proceedings of the National Academy of Sciences of the United States of America.

ADF/cofilin use an intrinsic mode of F-actin instability to disrupt actin filaments

E. Egelman, M. Vanloock, V. Galkin, 2003, The Journal of cell biology.

Remodeling of actin filaments by ADF/cofilin proteins

G. Schröder, E. Egelman, D. Kudryashov, 2011, Proceedings of the National Academy of Sciences.

Ca2+-induced movement of tropomyosin on native cardiac thin filaments revealed by cryoelectron microscopy

G. Schröder, D. Heeley, V. Galkin, 2017, Proceedings of the National Academy of Sciences.

Near-atomic resolution for one state of F-actin.

G. Schröder, E. Egelman, M. Vos, 2015, Structure.

BRCA2 BRC motifs bind RAD51-DNA filaments.

S. West, E. Egelman, Shixin Yang, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Structural polymorphism of the ParM filament and dynamic instability.

E. Egelman, R. Mullins, V. Galkin, 2009, Structure.

Filaments and fingers: Novel structural aspects of the single septin from Chlamydomonas reinhardtii

J. Brandão-Neto, R. DeMarco, V. Galkin, 2017, The Journal of Biological Chemistry.

Reversible paralysis of Schistosoma mansoni by forchlorfenuron, a phenylurea cytokinin that affects septins.

A. Loukas, P. Brindley, G. Rinaldi, 2014, International journal for parasitology.

Septins promote stress fiber–mediated maturation of focal adhesions and renal epithelial motility

V. Galkin, E. Spiliotis, J. R. Bowen, 2014, The Journal of cell biology.

Ca2+ attenuates nucleation activity of leiomodin

A. Kostyukova, C. Gregorio, V. Galkin, 2022, Protein science : a publication of the Protein Society.

The p65/RelA subunit of NF-kappaB interacts with actin-containing structures.

V. Galkin, A. Are, G. Pinaev, 2000, Experimental cell research.

Cleavage of Bacteriophage λ cI Repressor Involves the RecA C-terminal Domain

E. Egelman, Xiong Yu, C. Bell, 2009 .

Mapping the interaction of cofilin with subdomain 2 on actin.

S. Almo, E. Egelman, M. Thevis, 2007, Biochemistry.

The CH-domain of calponin does not determine the modes of calponin binding to F-actin.

Edward H Egelman, Vitold E Galkin, E. Egelman, 2006, Journal of molecular biology.

Optimization of small extracellular vesicle isolation from expressed prostatic secretions in urine for in‐depth proteomic analysis

P. Boutros, T. Kislinger, Lifang Yang, 2022, Journal of extracellular vesicles.

Each Actin Subunit Has Three Nebulin Binding Sites Implications for Steric Blocking

Kuan Wang, Edward H. Egelman, Vitold E. Galkin, 2002, Current Biology.

Structural Polymorphism in F-actin

Edward H. Egelman, Vitold E. Galkin, G. Schröder, 2010, Nature Structural &Molecular Biology.

Characterization and Evidence of the miR-888 Cluster as a Novel Cancer Network in Prostate

A. Esquela-Kerscher, O. J. Semmes, Lifang Yang, 2018, Molecular Cancer Research.

Enhancement of the RAD51 Recombinase Activity by the Tumor Suppressor PALB2

P. Sung, E. Egelman, Junjie Chen, 2010, Nature Structural &Molecular Biology.

Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2

Edward H Egelman, Xiong Yu, Vitold E Galkin, 2007, Nature Structural &Molecular Biology.

Cryo-electron microscopy reveals cardiac myosin binding protein-C M-domain interactions with the thin filament.

V. Galkin, S. Harris, H. White, 2022, Journal of molecular biology.

N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament.

G. Schröder, V. Galkin, S. Harris, 2018, Structure.

Salmonella SipA Polymerizes Actin by Stapling Filaments with Nonglobular Protein Arms

E. Egelman, M. Vanloock, C. E. Stebbins, 2003, Science.

The bacterial protein SipA polymerizes G-actin and mimics muscle nebulin

Edward H. Egelman, Daoguo Zhou, Jorge E. Galán, 2002, Nature Structural Biology.

High-Resolution Cryo-EM Structure of the Cardiac Actomyosin Complex.

Luisa U. Schäfer, G. Schröder, V. Galkin, 2020, Structure.

Anomalous structural dynamics of minimally frustrated residues in cardiac troponin C triggers hypertrophic cardiomyopathy†

P. Chase, Jerson L. Silva, E. Cino, 2021, Chemical science.

The structure of the native cardiac thin filament at systolic Ca2+ levels

P. Chase, V. Galkin, H. White, 2021, Proceedings of the National Academy of Sciences.

Effects of cardiomyopathy-linked mutations K15N and R21H in tropomyosin on thin-filament regulation and pointed-end dynamics

A. Kostyukova, C. T. Pappas, C. Gregorio, 2019, Molecular biology of the cell.

The Rad51/RadA N-terminal domain activates nucleoprotein filament ATPase activity.

E. Egelman, W. Heyer, Xiong Yu, 2006, Structure.

Septin 9 Exhibits Polymorphic Binding to F-Actin and Inhibits Myosin and Cofilin Activity.

V. Galkin, É. Forgács, D. Angelis, 2015, Journal of molecular biology.

The p65/RelA Subunit of NF-κB Interacts with Actin-Containing Structures

Vitold E. Galkin, V. Galkin, A. Are, 2000 .

Interaction of the C2 Ig-like Domain of Cardiac Myosin Binding Protein-C with F-actin.

V. Galkin, S. Harris, M. Patra, 2021, Journal of molecular biology.

Multimodal and Polymorphic Interactions between Anillin and Actin: Their Implications for Cytokinesis.

G. Hickson, Silvana Jananji, V. Galkin, 2017, Journal of molecular biology.

C0 and C1 N-terminal Ig domains of myosin binding protein C exert different effects on thin filament activation

Vitold E. Galkin, V. Galkin, S. Harris, 2016, Proceedings of the National Academy of Sciences.

Issues of resolution and polymorphism in single-particle reconstruction.

Edward H Egelman, Shixin Yang, Xiong Yu, 2003, Journal of structural biology.

Cleavage of bacteriophage lambda cI repressor involves the RecA C-terminal domain.

Jakub Bielnicki, Edward H Egelman, Xiong Yu, 2009, Journal of molecular biology.

High-resolution cryo-EM structure of the junction region of the native cardiac thin filament in relaxed state

P. Chase, V. Galkin, H. White, 2022, PNAS nexus.

The Arg non-receptor tyrosine kinase modifies F-actin structure.

E. Egelman, A. Koleske, V. Galkin, 2005, Journal of molecular biology.

The utrophin actin-binding domain binds F-actin in two different modes

Edward H. Egelman, Vitold E. Galkin, J. Ervasti, 2002, The Journal of cell biology.

Do the utrophin tandem calponin homology domains bind F-actin in a compact or extended conformation?

Edward H Egelman, Vitold E Galkin, E. Egelman, 2003, Journal of molecular biology.

Identification of an actin binding surface on vinculin that mediates mechanical cell and focal adhesion properties.

N. Dokholyan, R. Superfine, E. Egelman, 2014, Structure.

Crystal structure of the phage T4 recombinase UvsX and its functional interaction with the T4 SF2 helicase UvsW.

M. R. Webb, E. Egelman, S. White, 2011, Journal of molecular biology.

The RecB nuclease domain binds to RecA-DNA filaments: implications for filament loading.

E. Egelman, D. Wigley, Xiong Yu, 2009, Journal of molecular biology.

Divergence of Quaternary Structures Among Bacterial Flagellar Filaments

E. Egelman, Xiong Yu, J. Heuser, 2008, Science.

Loop 2 in Saccharomyces cerevisiae Rad51 protein regulates filament formation and ATPase activity

E. Egelman, W. Heyer, Xiong Yu, 2008, Nucleic acids research.

Complexes of RecA with LexA and RecX differentiate between active and inactive RecA nucleoprotein filaments.

E. Egelman, Shixin Yang, Xiong Yu, 2003, Journal of molecular biology.

Stabilization of RAD-51–DNA filaments via an interaction domain in Caenorhabditis elegans BRCA2

E. Egelman, S. Boulton, Xiong Yu, 2007, Proceedings of the National Academy of Sciences.

Refining the structure of the Halobacterium salinarum flagellar filament using the iterative helical real space reconstruction method: insights into polymorphism.

Edward H Egelman, Vitold E Galkin, E. Egelman, 2005, Journal of molecular biology.

The structure of bacterial ParM filaments

Edward H Egelman, Vitold E Galkin, E. Garner, 2007, Nature Structural &Molecular Biology.

The structure of the Salmonella typhimurium type III secretion system needle shows divergence from the flagellar system.

E. Egelman, T. Marlovits, V. Galkin, 2010, Journal of molecular biology.

Probing the structure of F-actin: cross-links constrain atomic models and modify actin dynamics.

E. Egelman, M. Vanloock, V. Galkin, 2001, Journal of molecular biology.

JCB_201405050 1..11

V. Galkin, E. Spiliotis, J. R. Bowen, 2014 .

The N-terminal domains of myosin binding protein C can bind polymorphically to F-actin.

E. Egelman, J. Trewhella, C. Jeffries, 2011, Journal of molecular biology.

The Structure of the CS1 Pilus of Enterotoxigenic Escherichia coli Reveals Structural Polymorphism

E. Egelman, Xiong Yu, L. Craig, 2012, Journal of bacteriology.

Two modes of binding of DinI to RecA filament provide a new insight into the regulation of SOS response by DinI protein.

E. Egelman, Xiong Yu, M. Cox, 2011, Journal of molecular biology.

Accurate flexible refinement of atomic models against medium-resolution cryo-EM maps using damped dynamics

Julio A. Kovacs, Willy Wriggers, Vitold E. Galkin, 2018, BMC Structural Biology.

Actin hydrophobic loop 262-274 and filament nucleation and elongation.

E. Egelman, M. Phillips, V. Galkin, 2008, Journal of molecular biology.

Cofilin cross-bridges adjacent actin protomers and replaces part of the longitudinal F-actin interface.

E. Egelman, D. Kudryashov, V. Galkin, 2006, Journal of molecular biology.

A New Internal Mode in F-Actin Helps Explain the Remarkable Evolutionary Conservation of Actin's Sequence and Structure

Edward H. Egelman, Vitold E. Galkin, E. Egelman, 2002, Current Biology.

Cardiac troponin T N-domain variant destabilizes the actin interface resulting in disturbed myofilament function

C. Ottenheijm, P. Chase, M. Papadaki, 2023, Proceedings of the National Academy of Sciences of the United States of America.

The location of ubiquitin in Lethocerus arthrin.

Belinda Bullard, Edward H Egelman, Vitold E Galkin, 2003, Journal of molecular biology.

ADF/cofilin use an intrinsic mode of F-actin instability to disrupt actin filaments

E. Egelman, V. Galkin, A. Orlova, 2003, The Journal of cell biology.

Remodeling of actin filaments by ADF/cofilin proteins

G. Schröder, E. Egelman, D. Kudryashov, 2011, Proceedings of the National Academy of Sciences.

Troponin structural dynamics in the native cardiac thin filament revealed by cryo electron microscopy.

V. Galkin, B. Belknap, C. Risi, 2024, Journal of molecular biology.

The Structure of the CS1 Pilus of Enterotoxigenic Escherichia coli Reveals Structural Polymorphism

E. Egelman, Xiong Yu, L. Craig, 2012, Journal of bacteriology.