Jeffrey C. Moore

发表

Pilot-scale production of intracellular and extracellular enzymes

B. Junker, M. Chartrain, Jeffrey C. Moore, 2001 .

Biocatalysis: Enzymatic Synthesis for Industrial Applications

U. Bornscheuer, Jeffrey C. Moore, Shuke Wu, 2020, Angewandte Chemie.

Rapid screening and scale-up of transaminase catalysed reactions.

Jeffrey C. Moore, M. Truppo, J. Rozzell, 2009, Organic & biomolecular chemistry.

Enabling Biocatalysis by High-Throughput Protein Engineering Using Droplet Microfluidics Coupled to Mass Spectrometry

C. Welch, R. Kennedy, Jeffrey C. Moore, 2018, ACS omega.

Mass Activated Droplet Sorting (MADS) Enables High Throughput Screening of Enzymatic Reactions at Nanoliter Scale.

Paul N. Devine, Daniel A Holland-Moritz, C. Welch, 2019, Angewandte Chemie.

Engineering the third wave of biocatalysis

G. Huisman, U. Bornscheuer, R. Kazlauskas, 2012, Nature.

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

Paul N. Devine, Gjalt W. Huisman, E. Mundorff, 2010, Science.

Advances in the Enzymatic Reduction of Ketones

Paul N. Devine, Jeffrey C. Moore, David Pollard, 2008 .

Design of an in vitro biocatalytic cascade for the manufacture of islatravir

Shane T. Grosser, Deeptak Verma, Edward C. Sherer, 2019, Science.

Convergent Kilogram-Scale Synthesis of Dual Orexin Receptor Antagonist

Paul N. Devine, Louis-Charles Campeau, Paul D. O’Shea, 2013 .

Directed evolution of a para-nitrobenzyl esterase for aqueous-organic solvents

Frances H. Arnold, F. Arnold, Jeffrey C. Moore, 1996, Nature Biotechnology.

Synthesis of ((3R,6R)-6-Methylpiperidin-3-yl)methanol via Biocatalytic Transamination and Crystallization-Induced Dynamic Resolution

Jeffrey C. Moore, John Y. L. Chung, P. Dormer, 2015 .

Unusual pyrimidine participation: efficient stereoselective synthesis of potent dual orexin receptor antagonist MK-6096.

K. Maloney, Jeffrey C. Moore, R. Reamer, 2014, Organic letters.

9.13 Industrially Relevant Enzymatic Reductions

Jeffrey C. Moore, S. Pannuri, C. Savile, 2012 .

Production of (S)-γ-fluoroleucine ethyl ester by enzyme mediated dynamic kinetic resolution: Comparison of batch and fed batch stirred tank processes to a packed bed column reactor

Paul N. Devine, Jeffrey C. Moore, M. Truppo, 2008 .

Combination of HDX-MS and in silico modeling to study enzymatic reactivity and stereo-selectivity at different solvent conditions.

Leo A. Joyce, Agustina Rodriguez-Granillo, E. Sherer, 2020, Journal of pharmaceutical and biomedical analysis.

Diverse Catalytic Reactions for the Stereoselective Synthesis of Cyclic Dinucleotide MK-1454.

Andrew J. Neel, Ben W. H. Turnbull, L. Tan, 2022, Journal of the American Chemical Society.

Enantioselective Synthesis of 4'-Ethynyl-2-fluoro-2'-deoxyadenosine (EFdA) via Enzymatic Desymmetrization.

D. Murray, L. Tan, Jeffrey C. Moore, 2017, Organic letters.

Asymmetric Synthesis of iso-Boc (S)-2-Amino-8-nonenoic Acid in One Through-Process

Jeffrey C. Moore, Feng Xu, Jeonghan Park, 2016 .

Development of an amine dehydrogenase for synthesis of chiral amines.

Andreas S Bommarius, E. Vázquez-Figueroa, A. Bommarius, 2012, Angewandte Chemie.

Effective synthesis of (S)-3,5-bistrifluoromethylphenyl ethanol by asymmetric enzymatic reduction

Jeffrey C. Moore, M. Truppo, D. Pollard, 2006 .

Scalable Asymmetric Synthesis of MK-8998, a T-Type Calcium Channel Antagonist.

L. Tan, Jeffrey C. Moore, J. Janey, 2021, The Journal of organic chemistry.

Advances in the enzymatic reduction of ketones.

Paul N Devine, Paul N. Devine, Jeffrey C. Moore, 2007, Accounts of chemical research.

Stereoselective synthesis of a potent thrombin inhibitor by a novel P2-P3 lactone ring opening.

Jeffrey C. Moore, M. Sturr, K. Gbewonyo, 2004, The Journal of organic chemistry.

2. Reductive Amination

G. Huisman, A. Chadha, Jeffrey C. Moore, 2012 .

Preparative Asymmetric Synthesis of 4,4-Dimethoxytetrahydro-2H-pyran-3-ol with a Ketone Reductase and in Situ Cofactor Recycling using Glucose Dehydrogenase

Jeffrey C. Moore, K. Telari, B. Kosjek, 2008 .

Overcoming "speed limits" in high throughput chromatographic analysis.

Christopher J Welch, Kerstin Zawatzky, C. Welch, 2017, Journal of chromatography. A.

"Site and Mutation"-Specific Predictions Enable Minimal Directed Evolution Libraries.

Katrina W. Lexa, S. Govindarajan, K. Hiraga, 2018, ACS synthetic biology.

Optimizing industrial enzymes by directed evolution.

F. Arnold, Jeffrey C. Moore, F H Arnold, 1997, Advances in biochemical engineering/biotechnology.

A kinase-cGAS cascade to synthesize a therapeutic STING activator

Steven P. Miller, Paul N. Devine, Matthew L. Maddess, 2022, Nature.

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

Paul N. Devine, E. Mundorff, Sarena Tam, 2010, Science.

Biocatalytic and chemocatalytic approaches to the highly stereoselective 1,2-reduction of an α,β-unsaturated ketone

D. Tellers, Jeffrey C. Moore, Roger N. Farr, 2006 .