S. Shimizu

发表

S. Shimizu, 2001 .

Secretion of Flavins by Shewanella Species and Their Role in Extracellular Electron Transfer

J. Lloyd, J. Ogawa, S. Shimizu, 2007, Applied and Environmental Microbiology.

M. Kobayashi, S. Shimizu, 2000, Current opinion in chemical biology.

Hydroxylation activity of P450 BM-3 mutant F87V towards aromatic compounds and its application to the synthesis of hydroquinone derivatives from phenolic compounds

Qing-Shan Li, R. Schmid, J. Ogawa, 2005, Applied Microbiology and Biotechnology.

Gene cloning, biochemical characterization and physiological role of a thermostable low-specificity L-threonine aldolase from Escherichia coli.

H. Yamada, M. Kataoka, S. Shimizu, 1998, European journal of biochemistry.

Bioelectrocatalytic reduction of dioxygen to water at neutral pH using bilirubin oxidase as an enzyme and 2,2′-azinobis (3-ethylbenzothiazolin-6-sulfonate) as an electron transfer mediator

Jun Ogawa, Sakayu Shimizu, Kenji Kano, 2001 .

Isolation and characterization of D-threonine aldolase, a pyridoxal-5'-phosphate-dependent enzyme from Arthrobacter sp. DK-38.

H. Yamada, M. Kataoka, S. Shimizu, 1997, European journal of biochemistry.

Biotechnology, 6. Special Applications

A. Fiechter, F. Stahl, H. Zorn, 2009 .

Versatile nitrilases: Nitrile‐hydrolysing enzymes

S. Shimizu, Michihiko Kobayashi, 1994 .

Bioconversion of substituted naphthalenes and β-eudesmol with the cytochrome P450 BM3 variant F87V

N. Misawa, H. Ikenaga, J. Ogawa, 2011, Applied Microbiology and Biotechnology.

Characterization of starch-accumulating duckweeds, Wolffia globosa, as renewable carbon source for bioethanol production

H. Kikukawa, S. Kishino, J. Ogawa, 2016 .

Nitrile-synthesizing enzyme: Screening, purification and characterization.

S. Shimizu, T. Kumano, Takahisa Suzuki, 2016, The Journal of general and applied microbiology.

Hyperinduction of nitrile hydratase acting on indole-3-acetonitrile in Agrobacterium tumefaciens

M. Kobayashi, S. Shimizu, T. Fujita, 1996, Applied Microbiology and Biotechnology.

Hydratases involved in nitrile conversion: screening, characterization and application.

S. Shimizu, H. Yamada, M. Kobayashi, 2002, Chemical record.

Discovery of a Novel Enzyme, Isonitrile Hydratase, Involved in Nitrogen-Carbon Triple Bond Cleavage*

S. Shimizu, Y. Hashimoto, Michihiko Kobayashi, 2001, The Journal of Biological Chemistry.

Screening of novel microbial enzymes for the production of biologically and chemically useful compounds.

M. Kobayashi, J. Ogawa, M. Kataoka, 1997, Advances in biochemical engineering/biotechnology.

A Novel Gene Cluster Including the Rhodococcus rhodochrous J1 nhlBA Genes Encoding a Low Molecular Mass Nitrile Hydratase (L-NHase) Induced by Its Reaction Product*

M. Kobayashi, S. Shimizu, H. Komeda, 1996, The Journal of Biological Chemistry.

Microbial and Enzymatic Processes for the Production of Biologically and Chemically Useful Compounds [New Synthetic Methods (69)]

S. Shimizu, H. Yamada, 1988 .

Diversity and versatility of microbial hydantoin-transforming enzymes

J. Ogawa, S. Shimizu, 1997 .

Cyclic ureide and imide metabolism in microorganisms producing a D-hydantoinase useful for D-amino acid production

J. Ogawa, S. Shimizu, C. Soong, 2001 .

Enzymes useful for chiral compound synthesis: structural biology, directed evolution, and protein engineering for industrial use

M. Tanokura, M. Kataoka, S. Shimizu, 2016, Applied Microbiology and Biotechnology.

Integration of exogenous DNA into the chromosome in all organisms

M. Ochiai, H. Kikukawa, J. Ogawa, 2018 .

Gene targeting in the oil-producing fungus Mortierella alpina 1 S-4 and 1 construction of a strain producing a valuable polyunsaturated fatty 2 acid by gene targeting

M. Ochiai, H. Kikukawa, J. Ogawa, 2017 .

Gene targeting in the oil-producing fungus Mortierella alpina 1S-4 and construction of a strain producing a valuable polyunsaturated fatty acid

M. Ochiai, H. Kikukawa, J. Ogawa, 2015, Current Genetics.

Purification and characterization of the lipase from Pseudomonas fluorescens HU380.

S. Shimizu, Y. Kojima, 2003, Journal of bioscience and bioengineering.

A novel lipase from Pseudomonas fluorescens HU380: gene cloning, overproduction, renaturation-activation, two-step purification, and characterization.

S. Shimizu, Michihiko Kobayashi, Y. Kojima, 2003, Journal of bioscience and bioengineering.

Production of eicosapentaenoic acid bySaprolegnia sp. 28YTF-1

N. Shirasaka, S. Shimizu, 1995 .

Production of an eicosapentaenoic acid-containing oil by a Δ12 desaturase-defective mutant ofMortierella alpina 1S-4

S. Shimizu, H. Yamada, S. Jareonkitmongkol, 1993 .

Microbial conversion of an oil containing α-linolenic acid to an oil containing eicosapentaenoic acid

S. Shimizu, H. Kawashima, H. Yamada, 1989 .

A novel membrane-integrated fermentation reactor system: application to pyruvic acid production in continuous culture by Torulopsis glabrata

S. Shimizu, Takashi Mimitsuka, H. Sawai, 2011, Bioprocess and biosystems engineering.

Structural basis of different substrate preferences of two old yellow enzymes from yeasts in the asymmetric reduction of enone compounds

K. Nagata, M. Tanokura, K. Shimomura, 2019, Bioscience, biotechnology, and biochemistry.

Establishment of Agrobacterium tumefaciens-Mediated Transformation of an Oleaginous Fungus, Mortierella alpina 1S-4, and Its Application for Eicosapentaenoic Acid Producer Breeding

Dian Anggraini Suroto, J. Ogawa, E. Sakuradani, 2009, Applied and Environmental Microbiology.

Sarcosine Oxidase Involved in Creatinine Degradation in Alcaligenes denitrificans subsp. denitrificans J9 and Arthrobacter spp. J5 and J11

S. Shimizu, H. Yamada, Jong Min Kim, 1986 .

Evidence for the presence of a cytosine deaminase that does not catalyze the deimination of creatine

S. Shimizu, H. Yamada, Jong Min Kim, 1987 .

Crystallization and Characterization of Sarcosine Oxidase from Alcaligenes denitrificans subsp. denitrificans

S. Shimizu, H. Yamada, Jong Min Kim, 1987 .

Stereoselective Reduction of Ethyl 4-Chloro-3-Oxobutanoate by a Microbial Aldehyde Reductase in an Organic Solvent-Water Diphasic System

M. Kataoka, S. Shimizu, T. Morikawa, 1990, Applied and environmental microbiology.

Cobalt proteins.

M. Kobayashi, S. Shimizu, 1999, European journal of biochemistry.

Site-directed mutagenesis for cysteine residues of cobalt-containing nitrile hydratase.

S. Shimizu, Ken-ichi Oinuma, Y. Hashimoto, 2002, Journal of inorganic biochemistry.

Metalloenzyme nitrile hydratase: Structure, regulation, and application to biotechnology

S. Shimizu, Michihiko Kobayashi, 1998, Nature Biotechnology.

Metabolism of polychlorinated dibenzo-p-dioxins by cytochrome P450 BM-3 and its mutant

K. Inouye, Qing-Shan Li, R. Schmid, 2004, Biotechnology Letters.

Enzymatic synthesis of chiral amino acid sulfoxides by Fe(II)/α-ketoglutarate-dependent dioxygenase

S. Smirnov, J. Ogawa, S. Shimizu, 2013 .

Metabolic engineering of Escherichia coli to produce (2S, 3R, 4S)-4-hydroxyisoleucine

S. Smirnov, J. Ogawa, S. Shimizu, 2010, Applied Microbiology and Biotechnology.

Sesamin is a potent and specific inhibitor of Δ5 desaturase in polyunsaturated fatty acid biosynthesis

S. Shimizu, H. Kawashima, M. Sugano, 1991, Lipids.

Polyunsaturated fatty acid saturation by gut lactic acid bacteria affecting host lipid composition

H. Kiyono, K. Ueda, M. Arita, 2013, Proceedings of the National Academy of Sciences.

Conjugated linoleic acid production from linoleic acid by lactic acid bacteria

S. Kishino, J. Ogawa, S. Shimizu, 2002 .

Enantioselective ester hydrolase from Sphingobacterium sp. 238C5 useful for chiral resolution of β-phenylalanine and for its β-peptide synthesis

J. Mano, J. Ogawa, S. Shimizu, 2009 .

Cytological and biochemical analysis of COF1, an Arabidopsis mutant of an ABC transporter gene.

T. Kuromori, K. Shinozaki, Asako Kamiya, 2007, Plant & cell physiology.

Synthesis of optically active ethyl 4-chloro-3-hydroxybutanoate by microbial reduction

M. Kataoka, S. Shimizu, M. Wada, 1999, Applied Microbiology and Biotechnology.

Construction of Deoxyriboaldolase-Overexpressing Escherichia coli and Its Application to 2-Deoxyribose 5-Phosphate Synthesis from Glucose and Acetaldehyde for 2′-Deoxyribonucleoside Production

J. Ogawa, S. Shimizu, M. Sasaki, 2003, Applied and Environmental Microbiology.

Barbiturase, a Novel Zinc-containing Amidohydrolase Involved in Oxidative Pyrimidine Metabolism*

J. Ogawa, E. Sakuradani, S. Shimizu, 2002, The Journal of Biological Chemistry.

A novel family of bacterial dioxygenases that catalyse the hydroxylation of free L-amino acids.

S. Smirnov, J. Ogawa, S. Shimizu, 2012, FEMS microbiology letters.

Gene cloning and overexpression of two conjugated polyketone reductases, novel aldo-keto reductase family enzymes, of Candida parapsilosis

E. Sakuradani, M. Kataoka, S. Shimizu, 2004, Applied Microbiology and Biotechnology.

Microbial asymmetric reduction of ethyl 4-chloro-3-oxobutanoate to optically active ethyl-4-chloro-3-hydroxybutanoate

H. Yamada, M. Kataoka, S. Shimizu, 1990, Biotechnology Letters.

High yield synthesis of S-adenosylhomocysteine and related nucleosides by bacterial S-adenosylhomocysteine hydrolase.

S. Shimizu, H. Yamada, T. Oshiro, 1984 .

Enzymes Involved in the NADPH Regeneration System Coupled with Asymmetric Reduction of Carbonyl Compounds in Microorganisms.

H. Yamada, M. Kataoka, S. Shimizu, 1992, Bioscience, biotechnology, and biochemistry.

Novel Threonine Aldolases and Their Application to Stereospecific Synthesis of β‐Hydroxy‐α‐amino Acids

M. Kataoka, S. Shimizu, T. Morikawa, 1998 .

Structural basis of different substrate preferences of two old yellow enzymes from yeasts in the asymmetric reduction of enone compounds.

K. Nagata, M. Tanokura, K. Shimomura, 2019 .

Delta 9-fatty acid desaturase from arachidonic acid-producing fungus. Unique gene sequence and its heterologous expression in a fungus, Aspergillus.

M. Kobayashi, E. Sakuradani, S. Shimizu, 1999, European journal of biochemistry.

Purification and cDNA Cloning of LaIT2, a Novel Insecticidal Toxin from Venom of the Scorpion Liocheles australasiae

H. Miyagawa, M. Miyashita, Y. Nakagawa, 2009, Bioscience, biotechnology, and biochemistry.

Functional analyses and application of microbial lactonohydrolases

M. Kataoka, S. Shimizu, K. Honda, 2002 .

Synthesis of optically pure ethyl (S)-4-chloro-3-hydroxybutanoate by Escherichia coli transformant cells coexpressing the carbonyl reductase and glucose dehydrogenase genes

M. Kataoka, S. Shimizu, M. Wada, 2001, Applied Microbiology and Biotechnology.

Escherichia coli transformant expressing the glucose dehydrogenase gene from Bacillus megaterium as a cofactor regenerator in a chiral alcohol production system.

I. Urabe, H. Yanase, M. Kataoka, 1998, Bioscience, biotechnology, and biochemistry.

Different specificity of two types of Pseudomonas lipases for C20 fatty acids with a Delta5 unsaturated double bond and their application for selective concentration of fatty acids.

E. Sakuradani, S. Shimizu, Y. Kojima, 2006, Journal of bioscience and bioengineering.

Microbial and enzymatic processes for the production of pharmacologically important nucleosides

S. Shimizu, H. Yamada, Hideaki Yamada, 1984 .

Gene Cloning and Functional Analysis of a Second Δ6-Fatty Acid Desaturase from an Arachidonic Acid-producing Mortierella Fungus

E. Sakuradani, S. Shimizu, 2003, Bioscience, biotechnology, and biochemistry.

Δ6-Fatty acid desaturase from an arachidonic acid-producing Mortierella fungus

E. Sakuradani, S. Shimizu, Michihiko Kobayashi, 1999 .

Identification of Delta12-fatty acid desaturase from arachidonic acid-producing mortierella fungus by heterologous expression in the yeast Saccharomyces cerevisiae and the fungus Aspergillus oryzae.

T. Ashikari, M. Kobayashi, E. Sakuradani, 1999, European journal of biochemistry.

Ketopantoic acid reductase of Pseudomonas maltophilia 845. Purification, characterization, and role in pantothenate biosynthesis.

H. Yamada, M. Kataoka, S. Shimizu, 1988, The Journal of biological chemistry.

Expression of the Fusarium oxysporum lactonase gene in Aspergillus oryzae: molecular properties of the recombinant enzyme and its application

T. Minetoki, M. Kataoka, S. Shimizu, 2005, Applied Microbiology and Biotechnology.

Role of Acinetobacter calcoaceticus 3,4-dihydrocoumarin hydrolase in oxidative stress defence against peroxoacids.

E. Sakuradani, M. Kataoka, S. Shimizu, 2003, European journal of biochemistry.

Crystallization and preliminary X-ray crystallographic studies of the axin DIX domain.

Hideki Yamamoto, H. Ogata, H. Komori, 2007, Acta Crystallographica. Section F : Structural Biology and Crystallization Communications.

Nitrilase catalyzes amide hydrolysis as well as nitrile hydrolysis.

M. Kobayashi, S. Shimizu, M. Goda, 1998, Biochemical and biophysical research communications.

The catalytic mechanism of amidase also involves nitrile hydrolysis

M. Kobayashi, S. Shimizu, Michihiko Kobayashi, 1998, FEBS letters.

Purification and Properties of Pantothenate Kinase from B-evibaclerizt.nz ammolziagenes IFO 12071

Y. Tani, S. Shimizu, K. Ogata, 2008 .

Novel multi-component enzyme machinery in lactic acid bacteria catalyzing C=C double bond migration useful for conjugated fatty acid synthesis.

S. Kishino, J. Ogawa, S. Shimizu, 2011, Biochemical and biophysical research communications.

Aldehyde oxidase carrying an unusual subunit structure from Pseudomonas sp. MX‐058

M. Kataoka, S. Shimizu, H. Watanabe, 2008, Microbial biotechnology.

A novel NADP+‐dependent l‐1‐amino‐2‐propanol dehydrogenase from Rhodococcus erythropolis MAK154: a promising enzyme for the production of double chiral aminoalcohols

M. Kataoka, S. Shimizu, T. Ishige, 2006, Letters in applied microbiology.

Microbial production of optically active β-phenylalanine ethyl ester through stereoselective hydrolysis of racemic β-phenylalanine ethyl ester

J. Mano, J. Ogawa, S. Shimizu, 2006, Applied Microbiology and Biotechnology.

Purification and characterization of a novel esterase promising for the production of useful compounds from Microbacterium sp. 7-1W.

H. Ono, M. Kataoka, S. Shimizu, 2002, FEMS microbiology letters.

Purification and characterization of a novel lactonohydrolase, catalyzing the hydrolysis of aldonate lactones and aromatic lactones, from Fusarium oxysporum.

H. Yamada, M. Kataoka, S. Shimizu, 1992, European journal of biochemistry.

A novel NADPH-dependent carbonyl reductase of Candida macedoniensis: purification and characterization.

H. Yamada, M. Kataoka, S. Shimizu, 1992, Archives of biochemistry and biophysics.

β-Ureidopropionase with N-carbamoyl-α-l-amino acid amidohydrolase activity from an aerobic bacterium, Pseudomonas putida IFO 12996

J. Ogawa, S. Shimizu, 1994 .

Identification of a novel bifunctional Δ12/Δ15 fatty acid desaturase from a basidiomycete, Coprinus cinereus TD#822‐2

E. Sakuradani, S. Shimizu, Shuo Zhang, 2007 .

Delta6-fatty acid desaturase from an arachidonic acid-producing Mortierella fungus. Gene cloning and its heterologous expression in a fungus, Aspergillus.

M. Kobayashi, E. Sakuradani, S. Shimizu, 1999, Gene.

Expression, purification, crystallization and X-ray analysis of 3-quinuclidinone reductase from Agrobacterium tumefaciens.

K. Nagata, M. Tanokura, M. Kataoka, 2012, Acta crystallographica. Section F, Structural biology and crystallization communications.

Expression, purification, crystallization and preliminary X-ray analysis of carbonyl reductase S1 from Candida magnoliae.

M. Okai, M. Tanokura, M. Kataoka, 2012, Acta crystallographica. Section F, Structural biology and crystallization communications.

Expression, purification, crystallization and preliminary X-ray analysis of conjugated polyketone reductase C2 (CPR-C2) from Candida parapsilosis IFO 0708.

K. Nagata, M. Tanokura, N. Kitamura, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystallization and preliminary X-ray analysis of the NADPH-dependent 3-quinuclidinone reductase from Rhodotorula rubra.

K. Nagata, K. Miyazono, M. Tanokura, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystallization and preliminary X-ray diffraction study of lactonohydrolase from Fusarium oxysporum.

Y. Higuchi, K. Miki, M. Ohta, 1998, Acta crystallographica. Section D, Biological crystallography.

The YORE-YORE gene regulates multiple aspects of epidermal cell differentiation in Arabidopsis.

T. Wada, K. Okada, E. Sakuradani, 2003, The Plant journal : for cell and molecular biology.

Arachidonic acid production by the oleaginous fungus Mortierella alpina 1S-4: A review

H. Kikukawa, J. Ogawa, E. Sakuradani, 2018, Journal of advanced research.

BIOTECHNOLOGICALLY RELEVANT ENZYMES AND PROTEINS Identification of a novel fatty acid elongase with a wide substrate specificity from arachidonic acid-producing fungus Mortierella alpina 1S-4

E. Sakuradani, S. Shimizu, Haruna Suzuki, 2009 .

Identification of mutation sites on Delta12 desaturase genes from Mortierella alpina 1S-4 mutants.

E. Sakuradani, S. Shimizu, T. Abe, 2009, Journal of bioscience and bioengineering.

Functional analysis of a fatty acid elongase from arachidonic acid-producing Mortierella alpina 1S-4

E. Sakuradani, S. Shimizu, S. Murata, 2008, Applied Microbiology and Biotechnology.

Functional characterization of Δ9 and ω9 desaturase genes in Mortierella alpina 1S-4 and its derivative mutants

E. Sakuradani, S. Shimizu, T. Abe, 2006, Applied Microbiology and Biotechnology.

Expression of Δ6, Δ5 desaturase and GLELO elongase genes from Mortierella alpina for production of arachidonic acid in soybean [Glycine max (L.) Merrill] seeds

Yoshikazu Tanaka, M. Ochiai, Miyuki Ogawa, 2006 .

Transformation of oil-producing fungus, Mortierella alpina 1S-4, using Zeocin, and application to arachidonic acid production.

S. Takeno, M. Inohara-Ochiai, E. Sakuradani, 2005, Journal of bioscience and bioengineering.

Identification of mutation sites on delta5 desaturase genes from Mortierella alpina 1S-4 mutants.

E. Sakuradani, S. Shimizu, T. Abe, 2005, Journal of bioscience and bioengineering.

Improvement of arachidonic acid production by mutants with lower n-3 desaturation activity derived from Mortierella alpina 1S-4

J. Ogawa, E. Sakuradani, S. Shimizu, 2004, Applied Microbiology and Biotechnology.

Isolation and characterization of an ω3-desaturation-defective mutant of an arachidonic acid-producing fungus, Mortierella alpina 1S-4

E. Sakuradani, S. Shimizu, S. Jareonkitmongkol, 1994, Archives of Microbiology.

Concentration of eicosapentaenoic acid and docosahexaenoic acid in an arachidonic acid-producing fungus, Mortierella alpina 1S-4, grown with fish oil

S. Shimizu, H. Kawashima, H. Yamada, 1992, Applied Microbiology and Biotechnology.

Isolation and characterization of a Δ--desaturation-defective mutant of an arachidonic acid-producing fungus, Mortierella alpina 1S-4

E. Sakuradani, S. Shimizu, S. Jareonkitmongkol, 2002 .

Characterization of the second form of NADH-cytochrome b5 reductase gene from arachidonic acid-producing fungus Mortierella alpina 1S-4.

M. Čertík, M. Kobayashi, E. Sakuradani, 1999, Journal of bioscience and bioengineering.

Isolation and characterization of an ?3-desaturation-defective mutant of an arachidonic acid-producing fungus, Mortierella alpina 1S-4

E. Sakuradani, S. Shimizu, S. Jareonkitmongkol, 1994 .

Hydrazide synthesis: novel substrate specificity of amidase.

M. Kobayashi, S. Shimizu, M. Goda, 1999, Biochemical and biophysical research communications.

Characterization and Distribution of IS1164 that Exists in the High Molecular Mass Nitrile Hydratase Gene Cluster of the Industrial Microbe Rhodococcus rhodochrous J1

T. Beppu, H. Yamada, S. Shimizu, 1997 .

Characterization of the gene cluster of high-molecular-mass nitrile hydratase (H-NHase) induced by its reaction product in Rhodococcus rhodochrous J1.

M. Kobayashi, S. Shimizu, H. Komeda, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Purification and characterization of a new aldehyde oxidase from pseudomonas sp. AIU 362.

J. Ogawa, M. Kataoka, S. Shimizu, 2008, Journal of bioscience and bioengineering.

Effects of oleic, arachidonic and 5,8,11,14-nonadecatetraenoic acids on lipid secretion and ketogenesis in perfused rat liver

T. Amachi, S. Shimizu, H. Kawashima, 2006, Lipids.

Stereoselective enzymatic oxidation and reduction system for the production of d(−)-pantoyl lactone from a racemic mixture of pantoyl lactone

S. Shimizu, H. Yamada, H. Hata, 1987 .

Effect of pretreatment of hydrothermally processed rice straw with laccase-displaying yeast on ethanol fermentation

K. Kuroda, M. Ueda, Akihito Nakanishi, 2012, Applied Microbiology and Biotechnology.

Production of γ-linolenic acid in Lotus japonicus and Vigna angularis by expression of the Δ6-fatty-acid desaturase gene isolated from Mortierella alpina

Yoshikazu Tanaka, M. Ochiai, K. Matsui, 2005 .

l-Leucine 5-hydroxylase of Nostoc punctiforme is a novel type of Fe(II)/α-ketoglutarate-dependent dioxygenase that is useful as a biocatalyst

S. Smirnov, J. Ogawa, S. Shimizu, 2012, Applied Microbiology and Biotechnology.

Two extracellular proteins with alkaline peroxidase activity, a novel cytochrome c and a catalase-peroxidase, from Bacillus sp. No.13.

Qing-Shan Li, J. Ogawa, S. Xie, 2004, Biochimica et biophysica acta.

Production of dihomo-γ-linolenic acid byMortierella alpina 1S-4

S. Shimizu, H. Kawashima, Hideaki Yamada, 1989 .

Characterization of alkaliphilic laccase activity in the culture supernatant of Myrothecium verrucaria 24G-4 in comparison with bilirubin oxidase.

J. Ogawa, Hiromi Tanaka, S. Shimizu, 2004, FEMS microbiology letters.

Biohydrogenation of C20 polyunsaturated fatty acids by anaerobic bacteria[S]

S. Kishino, J. Ogawa, S. Shimizu, 2014, Journal of Lipid Research.

Inhibitory Effects of Capsaicinoids on Fatty Acid Desaturation in a Rat Liver Cell Line

K. Kobata, N. Nakano, N. Shirasaka, 2001, Bioscience, biotechnology, and biochemistry.

Note Inhibitory Effects of Capsaicinoids on in a Rat Liver Cell Line FattyAcid Desaturation JsgA

N. Nakano, Tatsuo Watanabe, S. Shimizu, 2022 .

Isolation and Characterization of Δ6-Desaturase, an ELO-Like Enzyme and Δ5-Desaturase from the Liverwort Marchantia Polymorpha and Production of Arachidonic and Eicosapentaenoic Acids in the Methylotrophic Yeast Pichia Pastoris

K. Yamato, K. Ohyama, H. Fukuzawa, 2004, Plant Molecular Biology.

Gene targeting in the oil-producing fungus Mortierella alpina 1S-4 and construction of a strain producing a valuable polyunsaturated fatty acid

M. Ochiai, H. Kikukawa, J. Ogawa, 2015, Current Genetics.

Establishment of an overall transformation system for an oil-producing filamentous fungus, Mortierella alpina 1S-4

S. Takeno, M. Inohara-Ochiai, T. Ashikari, 2004, Applied Microbiology and Biotechnology.

Synthesis of coenzyme A and its biosynthetic intermediates by microbial processes.

Y. Tani, S. Shimizu, K. Ogata, 1979, Methods in enzymology.

Structure of conjugated polyketone reductase from Candida parapsilosis IFO 0708 reveals conformational changes for substrate recognition upon NADPH binding

K. Nagata, M. Tanokura, N. Kitamura, 2013, Applied Microbiology and Biotechnology.

Lactone-ring-cleaving enzymes of microorganisms: their diversity and applications.

M. Kataoka, S. Shimizu, K. Honda, 2001, Journal of biotechnology.

Occurrence of enzymes involved in biosynthesis of indole-3-acetic acid from indole-3-acetonitrile in plant-associated bacteria, Agrobacterium and Rhizobium.

M. Kobayashi, S. Shimizu, T. Fujita, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Effect of pretreatment of hydrothermally processed rice straw with laccase-displaying yeast on ethanol fermentation

K. Kuroda, Akihito Nakanishi, J. Ogawa, 2012, Applied Microbiology and Biotechnology.

Production of Dihomo-γ-Linolenic Acid by a Δ5-Desaturase-Defective Mutant of Mortierella alpina 1S-4

N. Shirasaka, S. Shimizu, H. Kawashima, 1992 .

Fatty acid desaturation-defective mutants of an arachidonic acid-producing fungus, Mortierella alpina 1S-4

S. Shimizu, H. Yamada, S. Jareonkitmongkol, 1992 .

Whole organism biocatalysis.

Sakayu Shimizu, Kohsuke Honda, S. Shimizu, 2005, Current opinion in chemical biology.

Synthesis of Phosphatidylcholine Having a Very Long Chain Polyunsaturated Fatty Acid

K. Alam, S. Shimizu, N. Baba, 1998 .

Hydrolysis and Formation of Hydantoins

J. Ogawa, S. Shimizu, Nobuyuki Horinouchi, 2012 .

Separative preparation of the four stereoisomers of β-methylphenylalanine with N-carbamoyl amino acid amidohydrolases

M. Akamatsu, H. Miyagawa, J. Ogawa, 2001 .

Purification and characterization of NADPH-dependent carbonyl reductase, involved in stereoselective reduction of ethyl 4-chloro-3-oxobutanoate, from Candida magnoliae.

M. Kataoka, S. Shimizu, M. Wada, 1998, Bioscience, biotechnology, and biochemistry.

Characterization of aldehyde reductase of Sporobolomyces salmonicolor.

H. Yamada, M. Kataoka, S. Shimizu, 1992, Biochimica et biophysica acta.

Stereoselective reduction of ethyl 4-chloro-3-oxobutanoate by Escherichia coli transformant cells coexpressing the aldehyde reductase and glucose dehydrogenase genes

H. Yanase, M. Kataoka, S. Shimizu, 1999, Applied Microbiology and Biotechnology.

Biotechnology, 3. Cultivation of Microorganisms

A. Fiechter, R. Ulber, S. Shimizu, 2009 .

Production of chiral C3- and C4-units by microbial enzymes.

M. Kataoka, S. Shimizu, 1999, Advances in biochemical engineering/biotechnology.

Novel Chemoenzymatic Synthesis of d( — )-Pantoyl Lactone

S. Shimizu, H. Yamada, H. Hata, 1987 .

Stereoselective reduction of diketones by a novel carbonyl reductase from Candida parapsilosis

S. Shimizu, H. Yamada, H. Hata, 1990 .

Metabolic diversity in biohydrogenation of polyunsaturated fatty acids by lactic acid bacteria involving conjugated fatty acid production

S. Kishino, J. Ogawa, S. Shimizu, 2009, Applied Microbiology and Biotechnology.

Multi‐Enzymatic Synthesis of Optically Pure β‐Hydroxy α‐Amino Acids

S. Smirnov, J. Ogawa, S. Shimizu, 2015 .

Occurrence of Amidases in the Industrial Microbe Rhodococcus rhodochrous J1

S. Shimizu, H. Yamada, H. Komeda, 1993 .

A novel l-isoleucine hydroxylating enzyme, l-isoleucine dioxygenase from Bacillus thuringiensis, produces (2S,3R,4S)-4-hydroxyisoleucine.

S. Smirnov, J. Ogawa, Ryokichi Koyama, 2009, Biochemical and biophysical research communications.

l-Leucine 5-hydroxylase of Nostoc punctiforme is a novel type of Fe(II)/α-ketoglutarate-dependent dioxygenase that is useful as a biocatalyst

S. Smirnov, J. Ogawa, S. Shimizu, 2013, Applied Microbiology and Biotechnology.

Characterization of Bacillus thuringiensis l-Isoleucine Dioxygenase for Production of Useful Amino Acids

S. Smirnov, J. Ogawa, S. Shimizu, 2011, Applied and Environmental Microbiology.

A novel l-isoleucine metabolism in Bacillus thuringiensis generating (2S,3R,4S)-4-hydroxyisoleucine, a potential insulinotropic and anti-obesity amino acid

S. Smirnov, J. Mano, J. Ogawa, 2011, Applied Microbiology and Biotechnology.

Simultaneous recognition of two chiral centers in α,β-diastereomeric amino acids by an N-carbamoyl-L-α-amino acid amidohydrolase from Alcaligenes xylosoxidans

J. Ogawa, S. Xie, R. Indrati, 1999, Biotechnology Letters.

Evaluation of two alternative metabolic pathways for creatinine degradation in microorganisms

S. Shimizu, H. Yamada, Jong Min Kim, 1986, Archives of Microbiology.

Cyclic-Imide-Hydrolyzing Activity ofd-Hydantoinase from Blastobacter sp. Strain A17p-4

J. Ogawa, S. Shimizu, C. Soong, 1999, Applied and Environmental Microbiology.

A novel metabolic pathway for creatinine degradation in Pseudomonas putida 77

S. Shimizu, H. Yamada, Jong Min Kim, 1985 .

Purification and characterization of dihydroorotase fromPseudomonas putida

J. Ogawa, S. Shimizu, 1995, Archives of Microbiology.

Hydroxy fatty acid production by Pediococcus sp.

S. Kishino, J. Ogawa, S. Shimizu, 2013 .

Stereoselective synthesis of (R)-3-quinuclidinol through asymmetric reduction of 3-quinuclidinone with 3-quinuclidinone reductase of Rhodotorula rubra

M. Kataoka, S. Shimizu, F. Nomoto, 2009, Applied Microbiology and Biotechnology.

Identification of a Sterol Δ7 Reductase Gene Involved in Desmosterol Biosynthesis in Mortierella alpina 1S-4

E. Sakuradani, S. Shimizu, Shuo Zhang, 2007, Applied and Environmental Microbiology.

Inhibition of Δ5-desaturase in polyunsaturated fatty acid biosynthesis by (-)-asarinin and (-)-epiasarinin

S. Shimizu, H. Kawashima, Hideaki Yamada, 1992 .

Inhibitory effect of curcumin on fatty acid desaturation inMortierella alpina 1S-4 and rat liver microsomes

S. Shimizu, H. Kawashima, H. Yamada, 1992, Lipids.

Stimulatory Effect of Peanut Oil on the Production of Dihomo-γ-linolenic Acid by Filamentous Fungi

S. Shimizu, H. Kawashima, H. Yamada, 1989 .

Conjugated α-linolenic acid production from α-linolenic acid by Lactobacillus plantarum AKU 1009a

S. Kishino, J. Ogawa, S. Shimizu, 2003 .

Desaturase-defective fungal mutants: useful tools for the regulation and overproduction of polyunsaturated fatty acids

M. Čertík, E. Sakuradani, S. Shimizu, 1998 .

Conjugated Linoleic Acid Accumulation via 10-Hydroxy-12-Octadecaenoic Acid during Microaerobic Transformation of Linoleic Acid by Lactobacillus acidophilus

S. Kishino, J. Ogawa, S. Shimizu, 2001, Applied and Environmental Microbiology.

Production of conjugated fatty acids by lactic acid bacteria.

S. Kishino, J. Ogawa, S. Shimizu, 2005, Journal of bioscience and bioengineering.

Structure, Function, and Application of Microbial Lactonases

M. Kataoka, S. Shimizu, 1996, Chimia (Basel).

Novel bioreduction system for the production of chiral alcohols

M. Kataoka, S. Shimizu, M. Wada, 2003, Applied Microbiology and Biotechnology.

A novel NADPH-dependent aldehyde reductase, catalyzing asymmetric reduction of ß-keto acid esters, from Sporobolomyces salmonicolor: purification and characterization

M. Kataoka, S. Shimizu, H. Yamada, 1990 .

3,4-Dihydrocoumarin hydrolase with haloperoxidase activity from Acinetobacter calcoaceticus F46.

M. Kataoka, S. Shimizu, K. Honda, 2000, European journal of biochemistry.

Chiral alcohol synthesis with yeast carbonyl reductases

M. Kataoka, S. Shimizu, K. Kita, 1998 .

One-Step Microbial Conversion of a Racemic Mixture of Pantoyl Lactone to Optically Active d-(—)-Pantoyl Lactone

S. Shimizu, Hideaki Yamada, H. Hata, 1987, Applied and Environmental Microbiology.

Biotechnology, 5. Monitoring and Modeling of Bioprocesses

Thomas Becker, Sakayu Shimizu, Armin Fiechter, 2009 .

A first synthesis of a phosphatidylcholine bearing docosahexaenoic and tetracosahexaenoic acids

Y. Mori, S. Shimizu, N. Baba, 2001 .

Microbial enzymes involved in lactone compound metabolism and their biotechnological applications

M. Kataoka, S. Shimizu, K. Honda, 2007, Applied Microbiology and Biotechnology.

A novel dihydrocoumarin hydrolase from Acinetobacter calcoaceticus: application to the production of useful compounds

M. Kataoka, S. Shimizu, K. Honda, 2002 .

Microbial Production

S. Shimizu, Hideharu Anazawa, 2014, Springer Japan.

Directed evolution of an aminoalcohol dehydrogenase for efficient production of double chiral aminoalcohols.

M. Kataoka, S. Shimizu, S. Fukui, 2011, Journal of bioscience and bioengineering.

Gene cloning of an NADPH-dependent menadione reductase from Candida macedoniensis, and its application to chiral alcohol production

M. Kataoka, S. Shimizu, T. Ishige, 2006 .

Distribution and immunological characterization of microbial aldehyde reductases

M. Kataoka, S. Shimizu, Hideaki Yamada, 2004, Archives of Microbiology.

Molecular Cloning and Overexpression of the Gene Encoding an NADPH-Dependent Carbonyl Reductase from Candida magnoliae, Involved in Stereoselective Reduction of Ethyl 4-Chloro-3-oxobutanoate

M. Kataoka, S. Shimizu, M. Wada, 2000, Bioscience, biotechnology, and biochemistry.

Diversity of 4-chloroacetoacetate ethyl ester-reducing enzymes in yeasts and their application to chiral alcohol synthesis.

M. Kataoka, S. Shimizu, K. Kita, 1999, Journal of bioscience and bioengineering.

Enzymatic production of ethyl (R )-4-chloro-3-hydroxybutanoate: asymmetric reduction of ethyl 4-chloro-3-oxobutanoate by an Escherichia coli transformant expressing the aldehyde reductase gene from yeast

M. Kataoka, H. Yanase, M. Kataoka, 1997, Applied Microbiology and Biotechnology.

Cloning of the aldehyde reductase gene from a red yeast, Sporobolomyces salmonicolor, and characterization of the gene and its product

H. Yanase, T. Hashimoto, M. Kataoka, 1996, Applied and environmental microbiology.

Stereoselective Synthesis of Biologically and Pharmacologically Important Chemicals with Microbial Enzymes

S. Shimizu, H. Yamada, 1990 .

Novel Enzymatic Production of D-(-)-Pantoyl Lactone through the Stereospecific Reduction of Ketopantoic Acid

M. Kataoka, S. Shimizu, H. Yamada, 1990 .

Reduction of Ketopantoyl Lactone to D-(—)-Pantoyl Lactone by Microorganisms

S. Shimizu, H. Hata, Hideaki Yamada, 1984 .

Occurrence of multiple ethyl 4-chloro-3-oxobutanoate-reducing enzymes in Candida magnoliae.

M. Kataoka, S. Shimizu, M. Wada, 1999, Journal of bioscience and bioengineering.

An Engineered Old Yellow Enzyme that Enables Efficient Synthesis of (4R,6R)‐Actinol in a One‐Pot Reduction System

K. Nagata, M. Tanokura, N. Kitamura, 2015, Chembiochem : a European journal of chemical biology.

Cloning and overexpression of the old yellow enzyme gene of Candida macedoniensis, and its application to the production of a chiral compound.

M. Kataoka, S. Shimizu, M. Wada, 2004, Journal of biotechnology.

Optical resolution of racemic pantolactone with a novel fungal enzyme, lactonohydrolase

H. Yamada, M. Kataoka, S. Shimizu, 1995, Applied Microbiology and Biotechnology.

A new route to l-threo-3-[4-(methylthio)phenylserine], a key intermediate for the synthesis of antibiotics: recombinant low-specificity d-threonine aldolase-catalyzed stereospecific resolution

H. Yamada, S. Shimizu, T. Dairi, 1999, Applied Microbiology and Biotechnology.

Novel alcohol oxidase with glycolate oxidase activity from Ochrobactrum sp. AIU 033

S. Kishino, J. Ogawa, M. Kataoka, 2014 .

A new process for the production of coenzyme A and its intermediates with a microorganism.

Y. Tani, S. Shimizu, K. Ogata, 1972, Biochimica et biophysica acta.

Stereospecific conversion of a racemic pantoyl lactone to D‐(‐)‐pantoyl lactone through microbial oxidation and reduction reactions

M. Kataoka, S. Shimizu, H. Yamada, 2010 .

Practical resolution system for DL-pantoyl lactone using the lactonase from Fusarium oxysporum.

M. Kataoka, S. Shimizu, K. Honda, 2005, Journal of biotechnology.

Microbial production of chiral pantothenonitrile through stereospecific reduction of 2′-ketopantothenonitrile

H. Yamada, M. Kataoka, S. Shimizu, 1990, Biotechnology Letters.

Optical resolution of racemic pantoic acid through microbial stereoselective lactonization in an organic solvent/water two-phase system

M. Kataoka, S. Shimizu, H. Yamada, 1996 .

Synthesis of Chiral Intermediates for D‐Pantothenate Production by Microbial Enzymes

S. Shimizu, Hideaki Yamada, 1992 .

Purification, characterization and gene cloning of thermostable O-acetyl-L-serine sulfhydrylase forming beta-cyano-L-alanine.

S. Shimizu, H. Omura, T. Nagasawa, 2003, Journal of bioscience and bioengineering.

Nitrile-synthesizing enzyme: Gene cloning, overexpression and application for the production of useful compounds.

S. Shimizu, T. Kumano, Michihiko Kobayashi, 2016, The Journal of general and applied microbiology.

Production of Coenzyme A by a Mutant of Brevibacterium ammoniagenes Resistant to Oxypantetheine

S. Shimizu, Hideaki Yamada, Akihiko Esumi, 1984, Applied and environmental microbiology.

Unusual intracellular accumulation of S-adenosyl-L-methionine by microorganisms.

S. Shimizu, H. Yamada, S. Shiozaki, 1984 .

A New Process for the Production of Coenzyme A

Y. Tani, S. Shimizu, K. Ogata, 1973 .

A New Preparation Method of Coenzyme A with Microorganisms

Y. Tani, S. Shimizu, K. Ogata, 1970 .

[Nicotinic acid and nicotinamide].

M. Kobayashi, S. Shimizu, 1999, Nihon rinsho. Japanese journal of clinical medicine.

Construction of microbial platform for an energy-requiring bioprocess: practical 2′-deoxyribonucleoside production involving a C−C coupling reaction with high energy substrates

J. Ogawa, J. Shima, S. Shimizu, 2012, Microbial Cell Factories.

Screening and characterization of a phosphopentomutase useful for enzymatic production of 2'-deoxyribonucleoside.

J. Ogawa, S. Shimizu, Nobuyuki Horinouchi, 2009, New biotechnology.

Efficient Production of 2-Deoxyribose 5-Phosphate from Glucose and Acetaldehyde by Coupling of the Alcoholic Fermentation System of Baker’s Yeast and Deoxyriboaldolase-Expressing Escherichia coli

J. Ogawa, S. Shimizu, Nobuyuki Horinouchi, 2006, Bioscience, biotechnology, and biochemistry.

One-pot Microbial Synthesis of 2′-deoxyribonucleoside from Glucose, Acetaldehyde, and a Nucleobase

J. Ogawa, S. Shimizu, Nobuyuki Horinouchi, 2006, Biotechnology Letters.

Biochemical retrosynthesis of 2′-deoxyribonucleosides from glucose, acetaldehyde, and a nucleobase

J. Ogawa, S. Shimizu, Nobuyuki Horinouchi, 2005, Applied Microbiology and Biotechnology.

Microbial Production of 2-Deoxyribose 5-Phosphate from Acetaldehyde and Triosephosphate for the Synthesis of 2′-Deoxyribonucleosides

J. Ogawa, S. Shimizu, Nobuyuki Horinouchi, 2003, Bioscience, biotechnology, and biochemistry.

Residue size at position 87 of cytochrome P450 BM‐3 determines its stereoselectivity in propylbenzene and 3‐chlorostyrene oxidation

R. Schmid, J. Ogawa, S. Shimizu, 2001, FEBS letters.

Improvement of aldehyde tolerance and sequential aldol condensation activity of deoxyriboaldolase via immobilization on interparticle pore type mesoporous silica

H. Togashi, Yoshihiko Suzuki, J. Ogawa, 2011 .

Retrobiosynthetic Production of 2´-Deoxyribonucleoside from Glucose, Acetaldehyde, and Nucleobase through Multistep Enzymatic Reactions

J. Ogawa, S. Shimizu, Nobuyuki Horinouchi, 2009 .

Screening and Industrial Application of Unique Microbial Reactions Involved in Nucleic Acid and Lipid Metabolisms

S. Kishino, J. Ogawa, S. Shimizu, 2006, Bioscience, biotechnology, and biochemistry.

Screening for Unique Microbial Reactions Useful for Industrial Applications

J. Ogawa, S. Shimizu, 2005 .

A View From The Front Line of Industrial Uses of Microbial Enzymes

Jun Ogawa, Sakayu Shimizu, J. Ogawa, 2009 .

Industrial microbial enzymes: their discovery by screening and use in large-scale production of useful chemicals in Japan.

Jun Ogawa, Sakayu Shimizu, J. Ogawa, 2002, Current opinion in biotechnology.

Production of 8,11,14,17-cis-eicosatetraenoic acid (20:4ω-3) by a Δ5 and Δ12 desaturase-defective mutant of an arachidonic acid-producing fungus Mortierella alpina 1S-4

J. Ogawa, E. Sakuradani, S. Shimizu, 1998 .

Production of 8,11,14,17-cis-eicosatetraenoic acid by Δ5 desaturase-defective mutants of an arachidonic acid-producing fungus, Mortierella alpina

E. Sakuradani, S. Shimizu, H. Kawashima, 1997 .

Diversity of microbial threonine aldolases and their application

M. Kataoka, H. Yamada, S. Shimizu, 2000 .

Distribution of Threonine Aldolase Activity with Different Stereospecificities in Aerobic Bacteria.

H. Yamada, M. Kataoka, S. Shimizu, 1998, Bioscience, biotechnology, and biochemistry.

Purification and characterization of L-allo-threonine aldolase from Aeromonas jandaei DK-39.

H. Yamada, M. Kataoka, S. Shimizu, 1997, FEMS microbiology letters.

Lactone-ring-cleaving enzyme: genetic analysis, novel RNA editing, and evolutionary implications.

M. Kobayashi, M. Kataoka, S. Shimizu, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Identification of active sites in amidase: evolutionary relationship between amide bond- and peptide bond-cleaving enzymes.

Y. Fujiwara, M. Kobayashi, Y. Fujiwara, 1997, Proceedings of the National Academy of Sciences of the United States of America.

A novel transporter involved in cobalt uptake.

M. Kobayashi, S. Shimizu, H. Komeda, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Transcriptional regulation of the Rhodococcus rhodochrous J1 nitA gene encoding a nitrilase.

M. Kobayashi, S. Shimizu, H. Komeda, 1996, Proceedings of the National Academy of Sciences of the United States of America.

MpFAE3, a β-Ketoacyl-CoA Synthase Gene in the Liverwort Marchantia polymorpha L., Is Preferentially Involved in Elongation of Palmitic Acid to Stearic Acid

K. Yamato, K. Ohyama, H. Fukuzawa, 2003, Bioscience, biotechnology, and biochemistry.

Functional Analysis of a β-Ketoacyl-CoA Synthase Gene, MpFAE2, by Gene Silencing in the Liverwort Marchantia polymorpha L.

K. Yamato, K. Ohyama, H. Fukuzawa, 2003, Bioscience, biotechnology, and biochemistry.

Production of arachidonic acid and eicosapentaenoic acids by Marchantia polymorpha in cell culture

K. Katoh, S. Shimizu, S. Jareonkitmongkol, 1991 .

Attempt to simultaneously generate three chiral centers in 4-hydroxyisoleucine with microbial carbonyl reductases.

Koji Takahashi, J. Ogawa, S. Shimizu, 2017, Bioorganic & medicinal chemistry.

A novel strategy for enzymatic synthesis of 4-hydroxyisoleucine: identification of an enzyme possessing HMKP (4-hydroxy-3-methyl-2-keto-pentanoate) aldolase activity.

S. Smirnov, J. Ogawa, S. Shimizu, 2007, FEMS microbiology letters.

Synthesis of 4-Hydroxyisoleucine by the Aldolase–Transaminase Coupling Reaction and Basic Characterization of the Aldolase from Arthrobacter simplex AKU 626

S. Smirnov, J. Mano, J. Ogawa, 2007, Bioscience, biotechnology, and biochemistry.

Molecular evidence that the rate-limiting step for the biosynthesis of arachidonic acid in Mortierella alpina is at the level of an elongase

S. Takeno, M. Inohara-Ochiai, T. Ashikari, 2005, Lipids.

Biotechnology, 2. Metabolic Engineering

A. Fiechter, J. Wegener, S. Shimizu, 2009 .

Structural Analysis of Conjugated Linoleic Acid Produced by Lactobacillus plantarum, and Factors Affecting Isomer Production

T. Iwashita, S. Kishino, J. Ogawa, 2003, Bioscience, biotechnology, and biochemistry.

Improved production of various polyunsaturated fatty acids through filamentous fungus Mortierella alpina breeding

J. Ogawa, E. Sakuradani, S. Shimizu, 2009, Applied Microbiology and Biotechnology.

Cloning and Sequencing of the ura3 and ura5 Genes, and Isolation and Characterization of Uracil Auxotrophs of the Fungus Mortierella alpina 1S-4

S. Takeno, M. Inohara-Ochiai, T. Ashikari, 2004, Bioscience, biotechnology, and biochemistry.

Conversion of linseed oil to an eicosapentaenoic acid-containing oil by Mortierella alpina 1S-4 at low temperature

S. Shimizu, H. Kawashima, H. Yamada, 1989, Applied Microbiology and Biotechnology.

Production of odd chain polyunsaturated fatty acids byMortierella fungi

S. Shimizu, H. Kawashima, H. Yamada, 1991 .

S-Adenosyl-L-methionine Production by Saccharomyces sake. Optimization of the Culture Conditions for the Production of Cells with a High S-Adenosyl-L-methionine Content

S. Shimizu, S. Shiozaki, Hideaki Yamada, 1989 .

Production of S-adenosyl-l-methionine by Saccharomyces sake

S. Shimizu, S. Shiozaki, Hideaki Yamada, 1986 .

Production of arachidonic acid byMortierella fungi

E. Park, S. Shimizu, S. Fujikawa, 2002 .

Characterization of a trifunctional fatty acid desaturase from oleaginous filamentous fungus Mortierella alpina 1S-4 using a yeast expression system.

M. Ochiai, H. Kikukawa, S. Kishino, 2013, Journal of bioscience and bioengineering.

Identification of Mutation Sites on Δ6 Desaturase Genes from Mortierella alpina 1S-4 Mutants

E. Sakuradani, S. Shimizu, T. Abe, 2005, Bioscience, biotechnology, and biochemistry.

Production of arachidonic acid by Mortierella fungi

Hiroshi Kawashima, Sakayu Shimizu, S. Shimizu, 1989, Applied Microbiology and Biotechnology.

A novel fungal ω3-desaturase with wide substrate specificity from arachidonic acid-producing Mortierella alpina 1S-4

Sakayu Shimizu, Takahiro Abe, E. Sakuradani, 2005, Applied Microbiology and Biotechnology.

Enhancement of arachidonic acid production by Mortierella alpina 1S-4

S. Shimizu, S. Fujikawa, K. Akimoto, 1998 .

Microbial Production of Functional Polyunsaturated Fatty Acids and Their Derivatives

S. Kishino, J. Ogawa, E. Sakuradani, 2014 .

Polyunsaturated fatty acids production and transformation by Mortierella alpina and anaerobic bacteria

S. Kishino, J. Ogawa, E. Sakuradani, 2012 .

Single cell oil production by Mortierella alpina.

E. Sakuradani, S. Shimizu, 2009, Journal of biotechnology.

Occurrence of a novel sterol, 24,25-methylenecholest-5-en-3β-ol, inMortierella alpina 1S-4

S. Shimizu, H. Kawashima, M. Wada, 1992, Lipids.

Arachidonic Acid-Producing Mortierella alpina: Creation of Mutants and Molecular Breeding

S. Takeno, E. Sakuradani, S. Shimizu, 2005 .

Oils, Microbial Production

S. Kishino, J. Ogawa, E. Sakuradani, 2002 .

Production of C20 Polyunsaturated Fatty Acids by an Arachidonic Acid–Producing Fungus Mortierella alpina 1S-4 and Related Strains

J. Ogawa, E. Sakuradani, S. Shimizu, 2002 .

Production of Dihomo- √£-linolenic Acid, Arachidonic Acid and Eicosapentaenoic Acid by Filamentous Fungi

S. Shimizu, H. Kawashima, H. Yamada, 1992 .

Production of Arachidonic Acid by Mortierella elongata 1S-5

S. Shimizu, H. Yamada, Y. Shinmen, 1987 .

C 19 Odd-chain Polyunsaturated Fatty Acids te C 21-PUFAs in a Rat Liver Cell Line , and and Their Related Compounds Inhibit Their ( PUFAs ) Are Metabolized Curcumin , Gallic Acid , Desaturation

N. Nakano, N. Shirasaka, T. Murakami, 2017 .

Identification and production of n−8 odd-numbered polyunsaturated fatty acids by a Δ12 desaturation-defective mutant of Mortierella alpina 1S-4

E. Sakuradani, S. Shimizu, Shuo Zhang, 2006, Lipids.

The characteristics of desaturation of Trichoderma sp. AM076 and formation of 9,12,15-hexadecatrienoic acid (16 : 3ω1) through Δ15 desaturation of 9,12-hexadecadienoic acid

N. Shirasaka, H. Yoshizumi, S. Shimizu, 2005 .

Microbial conversion of palmitoleic acid to 9,12-hexadecadienoic acid (16:2ω4) by Trichoderma sp. AM076

N. Shirasaka, T. Murakami, H. Yoshizumi, 1998 .

Mortierella Species (Fungi): Production of C 20 Polyunsaturated Fatty Acids

S. Shimizu, S. Jareonkitmongkol, 1995 .

BIOTECHNOLOGICAL PROCESSES FOR PRODUCTION OF POLY-UNSATURATED FATTY ACIDS

S. Shimizu, H. Kawashima, H. Yamada, 1989 .

Eicosapentaenoic acid (EPA) production by an oleaginous fungus Mortierella alpina expressing heterologous the Δ17‐desaturase gene under ordinary temperature

H. Kikukawa, J. Ogawa, E. Sakuradani, 2015 .

Effects of mineral addition on the growth morphology of and arachidonic acid production by Mortierella alpina 1S-4

S. Shimizu, K. Akimoto, K. Higashiyama, 1998 .

A Novel Δ5-Desaturase-Defective Mutant of Mortierella alpina 1S-4 and Its Dihomo-γ-Linolenic Acid Productivity

E. Sakuradani, S. Shimizu, S. Jareonkitmongkol, 1993 .

Extracellular oxidases of Cerrena sp. complementarily functioning in artificial dye decolorization including laccase, manganese peroxidase, and novel versatile peroxidases

J. Ogawa, S. Shimizu, K. Yokozeki, 2012 .

Identification of an NADH-Cytochrome b5Reductase Gene from an Arachidonic Acid-Producing Fungus,Mortierella alpina 1S-4, by Sequencing of the Encoding cDNA and Heterologous Expression in a Fungus,Aspergillus oryzae

Sakayu Shimizu, E. Sakuradani, S. Shimizu, 1999, Applied and Environmental Microbiology.

Enzymatic synthesis of flavin adenine dinucleotide

Y. Tani, H. Yamada, S. Shimizu, 1983, Applied biochemistry and biotechnology.

Evaluation of pyrimidine- and hydantoin-degrading enzyme activities in aerobic bacteria

J. Ogawa, S. Shimizu, Takeshi Kaimura, 1994 .

Two laccase isoenzymes and a peroxidase of a commercial laccase-producing basidiomycete, Trametes sp. Ha1.

Masashi Minoda, J. Ogawa, S. Shimizu, 2010, New biotechnology.

Coordinate induction of peroxidase and H2O2-forming nucleoside oxidase in Flavobacterium meningosepticum

J. Ogawa, S. Shimizu, S. Koga, 1999 .

Title Disruption of lig 4 improves gene targeting efficiency in theoleaginous fungus

M. Ochiai, H. Kikukawa, J. Ogawa, 2019 .

Disruption of lig 4 improves gene targeting efficiency in the oleaginous fungus Mortierella alpina 1 S-4

M. Ochiai, H. Kikukawa, J. Ogawa, 2017 .

Disruption of lig4 improves gene targeting efficiency in the oleaginous fungus Mortierella alpina 1S-4.

M. Ochiai, H. Kikukawa, J. Ogawa, 2015, Journal of biotechnology.

Microbial production of dihomo-γ-linolenic acid by Δ5-desaturase gene-disruptants of Mortierella alpina 1S-4.

H. Kikukawa, J. Ogawa, E. Sakuradani, 2016, Journal of bioscience and bioengineering.

Metabolic engineering for the production of polyunsaturated fatty acids by oleaginous fungus Mortierella alpina 1S-4.

Jun Ogawa, Sakayu Shimizu, J. Ogawa, 2013, Journal of bioscience and bioengineering.

Transformation of an oleaginous zygomycete Mortierella alpina 1S-4 with the carboxin resistance gene conferred by mutation of the iron–sulfur subunit of succinate dehydrogenase

J. Ogawa, E. Sakuradani, S. Shimizu, 2009, Current Genetics.

Improvement of the Fatty Acid Composition of an Oil-Producing Filamentous Fungus, Mortierella alpina 1S-4, through RNA Interference with Δ12-Desaturase Gene Expression

S. Takeno, M. Inohara-Ochiai, T. Ashikari, 2005, Applied and Environmental Microbiology.

Various oils and detergents enhance the microbial production of farnesol and related prenyl alcohols.

E. Sakuradani, S. Shimizu, C. Ohto, 2008, Journal of bioscience and bioengineering.

Biotechnology, 1. General

A. Fiechter, D. Sell, R. Ulber, 2009 .

Conjugated linoleic acid production from castor oil by Lactobacillus plantarum JCM 1551

S. Kishino, J. Ogawa, S. Shimizu, 2004 .

Fatty Acid Desaturation and Elongation Reactions of Trichoderma sp. 1-OH-2-3

N. Shirasaka, S. Kishino, J. Ogawa, 2009 .

Derepression of FAD Pyrophosphorylase and Flavin Changes during Growth of Kloeckera sp. No. 2201 on Methanol

Y. Tani, S. Shimizu, K. Ogata, 1977 .

Flavin Changes of Kloeckera sp. No. 2201 during Adaptation to Methanol

Y. Tani, S. Shimizu, K. Ogata, 1977 .

Acidolysis and glyceride synthesis reactions using fatty acids with two Pseudomonas lipases having different substrate specificities.

E. Sakuradani, S. Shimizu, Y. Kojima, 2006, Journal of bioscience and bioengineering.

Overproduction of Geranylgeraniol by Metabolically Engineered Saccharomyces cerevisiae

A. Kondo, Kenro Tokuhiro, Haruo Takahashi, 2009, Applied and Environmental Microbiology.

Structural basis of stereospecific reduction by quinuclidinone reductase

K. Nagata, K. Miyazono, M. Tanokura, 2014, AMB Express.

Industrial production of dihomo-γ-linolenic acid by a Δ5 desaturase-defective mutant of Mortierella alpina 1S-4 Fungus

S. Shimizu, H. Kawashima, S. Fujikawa, 2000 .

Misa Expression 12-Desaturase Gene ∆ Interference with 1 S-4 , through RNA Mortierella alpina of an Oil-Producing Filamentous Fungus , Improvement of the Fatty Acid Composition

S. Takeno, M. Inohara-Ochiai, T. Ashikari, 2005 .

C19 Odd-chain Polyunsaturated Fatty Acids (PUFAs) Are Metabolized to C21-PUFAs in a Rat Liver Cell Line, and Curcumin, Gallic Acid, and Their Related Compounds Inhibit Their Desaturation

N. Nakano, N. Shirasaka, T. Murakami, 2000, Bioscience, biotechnology, and biochemistry.

Agent modifiant la fonction hépatique

S. Shimizu, M. Sugano, Y. Suwa, 1990 .

Crystallization and Characterization of an Extracellular Fungal Peroxidase

T. Amachi, S. Shimizu, S. Asami, 1986 .

Linoleic Acid Isomerase in Lactobacillus plantarum AKU1009a Proved to Be a Multi-Component Enzyme System Requiring Oxidoreduction Cofactors

S. Kishino, J. Ogawa, S. Shimizu, 2011, Bioscience, biotechnology, and biochemistry.

Biocatalysis, 1. General

A. Fiechter, S. Lütz, S. Shimizu, 2009 .

Engineering Cytochrome P450 BM-3 for Oxidation of Polycyclic Aromatic Hydrocarbons

R. Schmid, J. Ogawa, S. Shimizu, 2001, Applied and Environmental Microbiology.

Pantothenic Acid and Related Compounds

M. Kataoka, S. Shimizu, 2002 .

Cloning and overexpression of ketopantoic acid reductase gene from Stenotrophomonas maltophilia and its application to stereospecific production of d-pantoic acid

M. Kataoka, S. Shimizu, Dayong Si, 2012, Applied Microbiology and Biotechnology.

Lactonohydrolase-catalyzed optical resolution of pantoyl lactone: selection of a potent enzyme producer and optimization of culture and reaction conditions for practical resolution

H. Yamada, M. Kataoka, S. Shimizu, 1995, Applied Microbiology and Biotechnology.

A high yield method for the preparative synthesis of coenzyme A by combination of chemical and enzymic reactions

Y. Tani, H. Yamada, S. Shimizu, 1983, FEBS letters.

Synthesis of Coenzymes by Immobilized Cell System

Y. Tani, S. Shimizu, H. Yamada, 1980 .

Synthesis of Coenzyme A by Immobilized Bacterial Cells

Y. Tani, S. Shimizu, H. Yamada, 1979 .

Purification and Properties of Pantothenate Kinase from Brevibacterium ammoniagenes IFO 12071

Y. Tani, S. Shimizu, K. Ogata, 1973 .

Microbial transformation of hydantoins to amino acids. Part V. Synthesis of N-carbamyl-D-2-thienyl-glycine and D-2-thienylglycine by microbial hydantoinase.

Y. Tani, S. Shimizu, H. Yamada, 1980 .

Accumulation of prenyl alcohols by terpenoid biosynthesis inhibitors in various microorganisms

E. Sakuradani, S. Shimizu, C. Ohto, 2008, Applied Microbiology and Biotechnology.

Cloning and sequencing of a gene encoding of aldehyde oxidase in Pseudomonas sp. AIU 362.

J. Ogawa, M. Kataoka, S. Shimizu, 2012, Journal of bioscience and bioengineering.

Membrane-Integrated Fermentation System for Improving the Optical Purity of D-Lactic Acid Produced during Continuous Fermentation

Kyungsu Na, S. Shimizu, Takashi Mimitsuka, 2011, Bioscience, biotechnology, and biochemistry.

Microbial oxidases catalyzing conversion of glycolaldehyde into glyoxal.

J. Ogawa, M. Kataoka, S. Shimizu, 2012, New biotechnology.

Characterization of alcohol oxidase from Aspergillus ochraceus AIU 031.

J. Ogawa, M. Kataoka, S. Shimizu, 2007, The Journal of general and applied microbiology.

A Novel Amidase (Half-Amidase) for Half-Amide Hydrolysis Involved in the Bacterial Metabolism of Cyclic Imides

J. Ogawa, S. Shimizu, C. Soong, 2000, Applied and Environmental Microbiology.

Development of a whole-cell biocatalyst co-expressing P450 monooxygenase and glucose dehydrogenase for synthesis of epoxyhexane

H. Ohtake, V. Urlacher, J. Kato, 2012, Applied Microbiology and Biotechnology.

Gene Cloning, Nucleotide Sequencing, and Purification and Characterization of the Low-Specificityl-Threonine Aldolase from Pseudomonas sp. Strain NCIMB 10558

H. Yamada, M. Kataoka, S. Shimizu, 1998, Applied and Environmental Microbiology.

Purification, Characterization, and Gene Cloning of Purine Nucleosidase from Ochrobactrum anthropi

H. Hatanaka, T. Ashikari, T. Amachi, 2001, Applied and Environmental Microbiology.

Purification, Characterization, and Gene Cloning of Purine Nucleosidase from Ochrobactrum anthropi

H. Hatanaka, T. Ashikari, T. Amachi, 2001 .

Ochrobactrum anthropi Cloning of Purine Nucleosidase from Purification , Characterization , and Gene

H. Hatanaka, T. Ashikari, T. Amachi, 2001 .

The GLY1 gene of Saccharomyces cerevisiae encodes a low-specific L-threonine aldolase that catalyzes cleavage of L-allo-threonine and L-threonine to glycine--expression of the gene in Escherichia coli and purification and characterization of the enzyme.

H. Yamada, S. Shimizu, T. Dairi, 1997, European journal of biochemistry.

Ricinoleic Acid and Castor Oil as Substrates for Conjugated Linoleic Acid Production by Washed Cells of Lactobacillus plantarum

S. Kishino, J. Ogawa, S. Shimizu, 2002, Bioscience, biotechnology, and biochemistry.

Microbial production of conjugated fatty acids

S. Kishino, J. Ogawa, S. Shimizu, 2009 .

Regiospecific analysis by ethanolysis of oil with immobilized Candida antarctica lipase

Yomi Watanabe, Y. Shimada, T. Nagao, 2003, Lipids.

CLA production from ricinoleic acid by lactic acid bacteria

S. Kishino, J. Ogawa, S. Shimizu, 2003 .

Enzymatic preparation of D-β-acetylthioisobutyric acid and cetraxate hydrochloride using a stereo- and/or regioselective hydrolase, 3,4-dihydrocoumarin hydrolase from Acinetobacter calcoaceticus

M. Kataoka, S. Shimizu, K. Honda, 2002, Applied Microbiology and Biotechnology.

Enzymes useful for chiral compound synthesis: structural biology, directed evolution, and protein engineering for industrial use

M. Tanokura, M. Kataoka, S. Shimizu, 2016, Applied Microbiology and Biotechnology.

Characterization of the gene cluster of high-molecular-mass nitrile hydratase (H-NHase) induced by its reaction product in Rhodococcus rhodochrous J1.

M. Kobayashi, S. Shimizu, H. Komeda, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Purification and characterization of monovalent cation-activated levodione reductase from Corynebacterium aquaticum M-13.

S. Shimizu, M. Wada, S. Nakamori, 1999, Applied and environmental microbiology.

Distribution of methylthioadenosine phosphorylase in eubacteria

S. Shimizu, T. Abe, Hideaki Yamada, 1988 .

Biotechnology, 4. Downstream Processing

Sakayu Shimizu, Roland Ulber, Armin Fiechter, 2009 .

Production of a novel ω1-eicosapentaenoic acid by Mortierella alpina 1S-4 grown on 1-hexadecene

S. Shimizu, H. Kawashima, H. Yamada, 1991, Archives of Microbiology.

Production of 8,11-cis-eicosadienoic acid by a Δ5 and Δ12 desaturase-defective mutant derived from the arachidonic acid-producing fungus Mortierella alpina 1S-4

J. Ogawa, E. Sakuradani, S. Shimizu, 1999 .

Occurrence of two nonmethylene-interrupted Δ5 polyunsaturated fatty acids in a Δ6-desaturase-defective mutant of the fungus Mortierella alpina 1S-4

S. Shimizu, S. Jareonkitmongkol, Hideaki Yamada, 1993 .

Production of 5,8,11-cis-eicosatrienoic acid by a Δ12-desaturase-defective mutant ofMortierella alpina 1S-4

S. Shimizu, H. Kawashima, S. Jareonkitmongkol, 1992 .

Selective transport of divalent cations by transition metal permeases: the Alcaligenes eutrophus HoxN and the Rhodococcus rhodochrous NhlF

S. Shimizu, O. Degen, T. Eitinger, 1999, Archives of Microbiology.

Changes in Composition and Content of Mycolic Acids in Glutamate-Overproducing Corynebacterium glutamicum

E. Sakuradani, S. Shimizu, T. Kudo, 2006, Bioscience, biotechnology and biochemistry.

Structural basis for high substrate-binding affinity and enantioselectivity of 3-quinuclidinone reductase AtQR.

K. Nagata, M. Tanokura, M. Kataoka, 2014, Biochemical and biophysical research communications.

Overexpression of the gene encoding HMG-CoA reductase in Saccharomyces cerevisiae for production of prenyl alcohols

E. Sakuradani, S. Shimizu, C. Ohto, 2009, Applied Microbiology and Biotechnology.

Gene cloning and overproduction of low-specificity d-threonine aldolase from Alcaligenes xylosoxidans and its application for production of a key intermediate for parkinsonism drug

H. Yamada, M. Kataoka, S. Shimizu, 2000, Applied Microbiology and Biotechnology.

Low-specificity l-threonine aldolase of Pseudomonas sp. NCIMB 10558: purification, characterization and its application to β-hydroxy-α-amino acid synthesis

H. Yamada, S. Ito, S. Shimizu, 1998, Applied Microbiology and Biotechnology.

A novel enzyme, d-3-hydroxyaspartate aldolase from Paracoccus denitrificans IFO 13301: purification, characterization, and gene cloning

M. Kataoka, S. Shimizu, T. Dairi, 2003, Applied Microbiology and Biotechnology.

Purification and characterization of a novel enzyme, L-threo-3-hydroxyaspartate dehydratase, from Pseudomonas sp. T62.

H. Yamada, M. Kataoka, S. Shimizu, 1999, FEMS microbiology letters.

A Membrane-Integrated Fermentation Reactor System: Its Effects in Reducing the Amount of Sub-Raw Materials for D-Lactic Acid Continuous Fermentation by Sporolactobacillus laevolacticus

Kyungsu Na, S. Shimizu, Takashi Mimitsuka, 2012, Bioscience, biotechnology, and biochemistry.

L-allo-threonine aldolase with an H128Y/S292R mutation from Aeromonas jandaei DK-39 reveals the structural basis of changes in substrate stereoselectivity.

M. Okai, K. Nagata, M. Tanokura, 2014, Acta crystallographica. Section D, Biological crystallography.

Purification, characterization and gene cloning of thermostable O-acetyl-l-homoserine sulfhydrylase forming γ-cyano-α-aminobutyric acid

S. Shimizu, H. Omura, T. Nagasawa, 2003 .

Omega-3 eicosatetraenoic acid production by molecular breeding of the mutant strain S14 derived from Mortierella alpina 1S-4.

H. Kikukawa, J. Ogawa, E. Sakuradani, 2015, Journal of bioscience and bioengineering.

Identification of a novel bifunctional delta12/delta15 fatty acid desaturase from a basidiomycete, Coprinus cinereus TD#822-2.

E. Sakuradani, S. Shimizu, Shuo Zhang, 2007, FEBS Letters.

Enzymatic production of pyruvate from fumarate — an application of microbial cyclic-imide-transforming pathway

J. Ogawa, S. Shimizu, Masashi Ito, 2001 .

l-Pantoyl lactone dehydrogenase from Rhodococcus erythropolis: genetic analyses and application to the stereospecific oxidation of l-pantoyl lactone

M. Kataoka, S. Shimizu, K. Honda, 2012, Applied Microbiology and Biotechnology.

Chemoenzymatic Synthesis of Phospholipid Hydroperoxides

K. Yoneda, J. Iwasa, T. Kaneko, 2010 .

Cytosine deaminase that hydrolyzes creatinine to N-methylhydantoin in various cytosine deaminase-forming microorganisms

S. Shimizu, Hideaki Yamada, Jorg Min Kim, 1987, Archives of Microbiology.

β-Aryl-β-amino acid aminotransferase from Variovorax sp. JH2 is useful for enantioselective β-phenylalanine production

J. Mano, J. Ogawa, J. Shima, 2012 .

Microbial Production of Optically Active β-Phenylalanine through Stereoselective Degradation of Racemic β-Phenylalanine

J. Mano, J. Ogawa, S. Shimizu, 2006, Bioscience, biotechnology, and biochemistry.

Diversity of Cyclic Ureide Compound-, Dihydropyrimidine-, and Hydantoin-hydrolyzing Enzymes in Blastobacter sp. A17p-4

J. Ogawa, S. Shimizu, M. Honda, 1995 .

Nucleoside-Triphosphatase Activity of an ATP-Dependent Enzyme, N-Methylhydantoin Amidohydrolase

J. Ogawa, S. Shimizu, W. Nirdnoy, 1995 .

Studies on the Metabolism of Pantothenic Acid in Microorganisms Part II:Formation of Coenzyme A by Baker's Yeast

Y. Tani, S. Shimizu, K. Ogata, 1972 .

Studies on the Metabolism of Pantothenic Acid in Microorganisms Part III

Y. Tani, S. Shimizu, K. Ogata, 1972 .

Fungal mycelia as a novel source of eicosapentaenoic acid. Activation of enzyme(s) involved in eicosapentaenoic acid production at low temperature.

H. Yamada, S. Shimizu, H. Kawashima, 1988, Biochemical and biophysical research communications.

Acyl-CoA oxidase from Candida tropicalis.

Y. Tani, H. Yamada, S. Shimizu, 1979, Biochemical and biophysical research communications.

Luminol chemiluminescence reaction catalyzed by a microbial peroxidase.

H. Yamada, T. Amachi, H. Yoshizumi, 1990, Analytical Biochemistry.

Synthesis and Biological Activity of Fatty Acid Derivatives of Quinine

Hye-Sook Kim, Y. Wataya, Minoru Izumi, 2005, Bioscience, biotechnology, and biochemistry.

Biosynthesis and regulation of microbial polyunsaturated fatty acid production.

M. Čertík, S. Shimizu, S. Shimizu, 1999, Journal of bioscience and bioengineering.

Crystal structure of conjugated polyketone reductase (CPR‐C1) from Candida parapsilosis IFO 0708 complexed with NADPH

K. Nagata, M. Tanokura, M. Kataoka, 2013, Proteins.

Syntheses of Sphingomyelins and Ceramides Bearing a Docosahexaenoyl or Arachidonoyl Group.

S. Shimizu, N. Baba, S. Nakajima, 1998, Bioscience, biotechnology and biochemistry.

L-allo-threonine aldolase from Aeromonas jandaei DK-39: gene cloning, nucleotide sequencing, and identification of the pyridoxal 5'-phosphate-binding lysine residue by site-directed mutagenesis

H. Yamada, M. Kataoka, S. Shimizu, 1997, Journal of bacteriology.

Cloning, sequencing and expression analysis of a gene encoding alcohol oxidase in Paenibacillus sp. AIU 311.

J. Ogawa, M. Kataoka, S. Shimizu, 2010, Journal of bioscience and bioengineering.

Production and characterization of alcohol oxidase from Penicillium purpurescens AIU 063.

J. Ogawa, M. Kataoka, S. Shimizu, 2009, Journal of bioscience and bioengineering.

Purification and characterization of a novel alcohol oxidase from Paenibacillus sp. AIU 311.

S. Suzuki, J. Ogawa, M. Kataoka, 2007, Journal of bioscience and bioengineering.

Superoxide dismutases exhibit oxidase activity on aldehyde alcohols similar to alcohol oxidase from Paenibacillus sp. AIU 311.

J. Ogawa, M. Kataoka, S. Shimizu, 2008, Journal of bioscience and bioengineering.

Effects of Sesamin on Serum Lipoprotein Metabolism in Normocholesterolemic and Hypercholesterolemic Stroke‐Prone SHR

T. Murakami, S. Shimizu, H. Ogawa, 1993, Annals of the New York Academy of Sciences.

Indole Hydroxylation by Bacterial Cytochrome P450 BM-3 and Modulation of Activity by Cumene Hydroperoxide

R. Schmid, J. Ogawa, S. Shimizu, 2005, Bioscience, biotechnology, and biochemistry.

Genetic analysis around aminoalcohol dehydrogenase gene of Rhodococcus erythropolis MAK154: a putative GntR transcription factor in transcriptional regulation

M. Kataoka, S. Shimizu, T. Ishige, 2011, Applied Microbiology and Biotechnology.

A new aldehyde oxidase catalyzing the conversion of glycolaldehyde to glycolate from Burkholderia sp. AIU 129.

S. Kishino, J. Ogawa, M. Kataoka, 2015, Journal of bioscience and bioengineering.

Achlorophyllous alga Prototheca zopfii oxidizes n-alkanes with different carbon-chain lengths through a unique subterminal oxidation pathway.

J. Ogawa, E. Sakuradani, S. Shimizu, 2014, Journal of bioscience and bioengineering.

Subterminal oxidation of n-alkanes in achlorophyllous alga Prototheca sp.

J. Ogawa, E. Sakuradani, S. Shimizu, 2013, Journal of bioscience and bioengineering.

Studies on the Metabolism of Pantothenic Acid in Microorganisms Part III:Formation of Coenzyme A by Brevibacterium amtnoniagenes IFO 12071

Y. Tani, S. Shimizu, K. Ogata, 1972 .

Production of Arachidonic Acid by Mortierella elongata 1S-5

S. Shimizu, H. Yamada, Y. Shinmen, 1987 .

Metabolic diversity in biohydrogenation of polyunsaturated fatty acids by lactic acid bacteria involving conjugated fatty acid production

S. Kishino, J. Ogawa, S. Shimizu, 2009, Applied Microbiology and Biotechnology.

Microbial production of conjugated γ‐linolenic acid from γ‐linolenic acid by Lactobacillus plantarum AKU 1009a

S. Kishino, J. Ogawa, S. Shimizu, 2010, Journal of Applied Microbiology.

LplR, a Repressor Belonging to the TetR Family, Regulates Expression of the l-Pantoyl Lactone Dehydrogenase Gene in Rhodococcus erythropolis

M. Kataoka, S. Shimizu, Dayong Si, 2012, Applied and Environmental Microbiology.

Enzymatic Synthesis of Phosphatidylinositol Bearing Polyunsaturated Acyl Group

S. Shimizu, N. Baba, S. Nakajima, 1996 .

Isolation and characterization of delta(6)-desaturase, an ELO-like enzyme and delta(5)-desaturase from the liverwort Marchantia polymorpha and production of arachidonic and eicosapentaenoic acids in the methylotrophic yeast Pichia pastoris.

K. Yamato, K. Ohyama, H. Fukuzawa, 2004, Plant molecular biology.

Characterization of a trifunctional fatty acid desaturase from oleaginous filamentous fungus Mortierella alpina 1S-4 using a yeast expression system.

M. Ochiai, H. Kikukawa, S. Kishino, 2013, Journal of bioscience and bioengineering.