A. Sieben

发表

Alzheimer ’ s disease and driving : review of the literature and consensus guideline from Belgian dementia experts and

M. Ventura, S. Engelborghs, E. Salmon, 2017 .

Distinct [18F]THK5351 binding patterns in primary progressive aphasia variants

P. Dupont, R. Peeters, Y. Pijnenburg, 2018, European Journal of Nuclear Medicine and Molecular Imaging.

Single-word comprehension deficits in the nonfluent variant of primary progressive aphasia

P. Dupont, R. Peeters, Y. Pijnenburg, 2018, Alzheimer's Research & Therapy.

Multivariate analysis reveals anatomical correlates of naming errors in primary progressive aphasia

B. Bergmans, S. Sunaert, Y. Pijnenburg, 2019, Neurobiology of Aging.

Loss of DPP6 in neurodegenerative dementia: a genetic player in the dysfunction of neuronal excitability

K. Sleegers, C. van Broeckhoven, S. Engelborghs, 2019, Acta Neuropathologica.

Impaired Processing of Serial Order Determines Working Memory Impairments in Alzheimer's Disease.

W. Fias, M. De Belder, P. Santens, 2017, Journal of Alzheimer's disease : JAD.

A Retrospective Belgian Multi-Center MRI Biomarker Study in Alzheimer’s Disease (REMEMBER)

D. Smeets, B. Bergmans, H. Struyfs, 2018, Journal of Alzheimer's disease : JAD.

Neoplasm Related Encephalopathies

P. Santens, A. Sieben, L. Lapeire, 2012 .

Terbutaline causes immobilization of single β2-adrenergic receptor-ligand complexes in the plasma membrane of living A549 cells as revealed by single-molecule microscopy.

U. Kubitscheck, H. Häberlein, Tim P Kaminski, 2011, Journal of biomedical optics.

Late-onset post-irradiation vasculopathy of the posterior cerebral vasculature

E. Achten, D. Hemelsoet, T. Boterberg, 2012, Acta Neurologica Belgica.

The C9orf72 repeat size correlates with onset age of disease, DNA methylation and transcriptional downregulation of the promoter

C. Broeckhoven, C. van Broeckhoven, S. Engelborghs, 2015, Molecular Psychiatry.

Diagnostic value of cerebrospinal fluid tau, neurofilament, and progranulin in definite frontotemporal lobar degeneration

C. van Broeckhoven, S. Engelborghs, P. D. De Deyn, 2018, Alzheimer's Research & Therapy.

Cerebellar ataxia in progressive supranuclear palsy: a clinico-pathological case report

P. Parizel, A. Sieben, S. Ceyssens, 2021, Acta neurologica Belgica.

Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration

F. Jessen, G. Frisoni, T. Strom, 2014, Acta Neuropathologica.

Distinct clinical characteristics of C9orf72 expansion carriers compared with GRN, MAPT, and nonmutation carriers in a Flanders-Belgian FTLD cohort.

C. van Broeckhoven, S. Engelborghs, R. Vandenberghe, 2013, JAMA neurology.

Extended FTLD pedigree segregating a Belgian GRN-null mutation: neuropathological heterogeneity in one family

C. van Broeckhoven, S. Engelborghs, R. Vandenberghe, 2018, Alzheimer's Research & Therapy.

Clinical variability and onset age modifiers in an extended Belgian GRN founder family

B. Bergmans, K. Sleegers, C. van Broeckhoven, 2018, Neurobiology of Aging.

No supportive evidence for TIA1 gene mutations in a European cohort of ALS-FTD spectrum patients

B. Bergmans, C. van Broeckhoven, S. Engelborghs, 2018, Neurobiology of Aging.

Mutations in RNU7-1 Weaken Secondary RNA Structure, Induce MCP-1 and CXCL10 in CSF, and Result in Aicardi-Goutières Syndrome with Severe End-Organ Involvement

P. Verloo, Y. Crow, B. Ogunjimi, 2022, Journal of Clinical Immunology.

A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum: a gene identification study

S. Pereson, C. Broeckhoven, K. Sleegers, 2012, The Lancet Neurology.

Teenage-onset progressive myoclonic epilepsy due to a familial C9orf72 repeat expansion

C. van Broeckhoven, S. Berkovic, A. Meurs, 2018, Neurology.

Long lasting trigeminal neuropathy, limbic encephalitis and abdominal ganglionitis without primary cancer: An atypical case of Hu-antibody syndrome

K. Geboes, A. Sieben, M. Lammens, 2020, Clinical Neurology and Neurosurgery.

Clinical features of TBK1 carriers compared with C9orf72, GRN and non-mutation carriers in a Belgian cohort

C. van Broeckhoven, S. Engelborghs, R. Vandenberghe, 2015, Brain : a journal of neurology.

Motor neuron degeneration in spastic paraplegia 11 mimics amyotrophic lateral sclerosis lesions

A. Brice, G. Stevanin, A. Malandrini, 2016, Brain : a journal of neurology.

Early-onset dementia, leukoencephalopathy and brain calcifications: a clinical, imaging and pathological comparison of ALSP and PLOSL/Nasu Hakola disease

I. Goethals, D. Hemelsoet, A. Sieben, 2018, Acta Neurologica Belgica.

Characteristics and Outcomes of Patients with Seizures according to the Time of Onset in Relation to Stroke

G. van Maele, A. Sieben, J. De Reuck, 2008, European Neurology.

Proteomic Assessment of C57BL/6 Hippocampi after Non-Selective Pharmacological Inhibition of Nitric Oxide Synthase Activity: Implications of Seizure-like Neuronal Hyperexcitability Followed by Tauopathy

K. Laukens, G. D. De Meyer, A. Sieben, 2022, Biomedicines.

Bilingualism and Cognitive Decline: A Story of Pride and Prejudice.

W. Duyck, P. Santens, Evy Woumans, 2017, Journal of Alzheimer's disease : JAD.

Running title : Bilingualism and cognitive decline Bilingualism and cognitive decline : A story of pride and prejudice

W. Duyck, P. Santens, Evy Woumans, 2017 .

Determination of cellulase activity using hydroxyethylcellulose as substrate.

D. Eveleigh, A. Sieben, J. J. Child, 1973, Canadian journal of biochemistry.

Diagnostic Performance of Automated MRI Volumetry by icobrain dm for Alzheimer’s Disease in a Clinical Setting: A REMEMBER Study

D. Smeets, B. Bergmans, H. Struyfs, 2021, Journal of Alzheimer's disease : JAD.

Improved Alzheimer’s disease versus frontotemporal lobar degeneration differential diagnosis combining EEG and neurochemical biomarkers

M. de Vos, C. van Broeckhoven, S. Engelborghs, 2019 .

Reduction of high-affinity beta2-adrenergic receptor binding by hyperforin and hyperoside on rat C6 glioblastoma cells measured by fluorescence correlation spectroscopy.

H. Häberlein, A. Sieben, D. Weiser, 2007, Biochemistry.

An improved preparative method for D-erythrose 4-phosphate.

A. Sieben, A. Perlin, F. J. Simpson, 1966, Canadian journal of biochemistry.

[6] Erythrose 4-phosphate

A. Sieben, A. Perlin, F. J. Simpson, 1966 .

iPSC-derived cortical neurons to study sporadic Alzheimer disease: a transcriptome comparison with post-mortem brain samples.

M. Nazaruk, F. Caiment, A. Sieben, 2021, Toxicology letters.

Amyloid-β1–43 cerebrospinal fluid levels and the interpretation of APP, PSEN1 and PSEN2 mutations

B. Bergmans, K. Sleegers, C. van Broeckhoven, 2020, Alzheimer's Research & Therapy.

Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD

K. Verstrepen, C. van Broeckhoven, W. Robberecht, 2016, Scientific Reports.

Phenotypic characteristics of Alzheimer patients carrying an ABCA7 mutation

K. Sleegers, C. van Broeckhoven, S. Engelborghs, 2016, Neurology.

Investigating the role of ALS genes CHCHD10 and TUBA4A in Belgian FTD-ALS spectrum patients

B. Bergmans, C. Broeckhoven, S. Engelborghs, 2017, Neurobiology of Aging.

Clinical Evidence of Disease Anticipation in Families Segregating a C9orf72 Repeat Expansion

K. Sleegers, C. van Broeckhoven, S. Engelborghs, 2017, JAMA neurology.

A Pan-European Study of the C9orf72 Repeat Associated with FTLD: Geographic Prevalence, Genomic Instability, and Intermediate Repeats

F. Jessen, G. Frisoni, K. Sleegers, 2012, Human mutation.

Partial deletion of AFG3L2 causing spinocerebellar ataxia type 28

E. Rugarli, P. Parizel, W. van Hecke, 2014, Neurology.

The Electrophysiological Correlates of Phoneme Perception in Primary Progressive Aphasia: A Preliminary Case Series

M. Miatton, P. van Mierlo, M. De Letter, 2021, Frontiers in Human Neuroscience.

Dura mater graft-associated Creutzfeldt–Jakob disease with an incubation period of 30 years, mimicking non-convulsive status epilepticus

A. Meurs, A. Sieben, Bart De Vil, 2019, Acta Neurologica Belgica.

Neurogranin as biomarker in CSF is non-specific to Alzheimer's disease dementia

C. van Broeckhoven, S. Engelborghs, P. Cras, 2021, Neurobiology of Aging.

Investigating the role of filamin C in Belgian patients with frontotemporal dementia linked to GRN deficiency in FTLD-TDP brains

Patrick Santens, Mathieu Vandenbulcke, Adrian Ivanoiu, 2015, Acta neuropathologica communications.

The genetics and neuropathology of frontotemporal lobar degeneration

C. van Broeckhoven, S. Engelborghs, P. Boon, 2012, Acta Neuropathologica.

Single-word comprehension deficits in the nonfluent variant of primary progressive aphasia

P. Dupont, R. Peeters, Y. Pijnenburg, 2018, Alzheimer's Research & Therapy.

α-Hederin inhibits G protein-coupled receptor kinase 2-mediated phosphorylation of β2-adrenergic receptors.

J. Schulte-Michels, A. Sieben, A. Wolf, 2016, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Alzheimer's disease, apolipoprotein E and hormone replacement therapy.

H. Depypere, S. Weyers, A. Sieben, 2016, Maturitas.

5 Neoplasm Related Encephalopathies

P. Santens, A. Sieben, L. Lapeire, 2012 .

Dementia, End of Life, and Euthanasia: A Survey Among Dementia Specialists Organized by the Belgian Dementia Council.

M. Ventura, S. Engelborghs, E. Salmon, 2019, Journal of Alzheimer's disease : JAD.

Clinical utility and applicability of biomarker-based diagnostic criteria for Alzheimers disease : a BeDeCo survey Reference

Kurt, P. Deyn, M. Ventura, 2015 .

Clinical utility and applicability of biomarker-based diagnostic criteria for Alzheimer’s disease: a BeDeCo survey

M. Ventura, S. Engelborghs, E. Salmon, 2015, Acta Neurologica Belgica.

EEG Dominant Frequency Peak Differentiates Between Alzheimer’s Disease and Frontotemporal Lobar Degeneration

P. Deyn, C. Broeckhoven, H. Struyfs, 2016 .

Bilingualism delays clinical manifestation of Alzheimer's disease

Michaël A. Stevens, W. Duyck, P. Santens, 2015 .

Monoaminergic impairment in Down syndrome with Alzheimer's disease compared to early-onset Alzheimer's disease

A. Lleó, R. Blesa, J. Fortea, 2017, Alzheimer's & dementia.

Alpha-hederin, but not hederacoside C and hederagenin from Hedera helix, affects the binding behavior, dynamics, and regulation of beta 2-adrenergic receptors.

D. Jakobs, F. Runkel, A. Sieben, 2009, Biochemistry.

Loss of TBK1 is a frequent cause of frontotemporal dementia in a Belgian cohort

C. van Broeckhoven, S. Engelborghs, R. Vandenberghe, 2015, Neurology.

Rare nonsynonymous variants in SORT1 are associated with increased risk for frontotemporal dementia

G. Frisoni, C. Broeckhoven, S. Engelborghs, 2018, Neurobiology of Aging.

NEK1 genetic variability in a Belgian cohort of ALS and ALS-FTD patients

C. Broeckhoven, S. Engelborghs, R. Vandenberghe, 2018, Neurobiology of Aging.

Cerebellar ataxia in progressive supranuclear palsy: a clinico-pathological case report

P. Parizel, A. Sieben, S. Ceyssens, 2021, Acta Neurologica Belgica.

Family-based exome sequencing identifies RBM45 as a possible candidate gene for frontotemporal dementia and amyotrophic lateral sclerosis

P. Deyn, C. Broeckhoven, S. Engelborghs, 2021, Neurobiology of Disease.

A case series of verbal semantic processing in primary progressive aphasia: Evidence from the N400 effect.

M. Miatton, P. van Mierlo, M. De Letter, 2021, International journal of language & communication disorders.

Hippocampal Sclerosis in Frontotemporal Dementia: When Vascular Pathology Meets Neurodegeneration.

R. Raedt, C. van Broeckhoven, S. Engelborghs, 2021, Journal of neuropathology and experimental neurology.

Mutated CTSF in adult-onset neuronal ceroid lipofuscinosis and FTD

C. van Broeckhoven, S. Engelborghs, J. Verhoeven, 2016, Neurology: Genetics.

Early-onset dementia, leukoencephalopathy and brain calcifications: a clinical, imaging and pathological comparison of ALSP and PLOSL/Nasu Hakola disease

I. Goethals, D. Hemelsoet, A. Sieben, 2018, Acta Neurologica Belgica.

Contribution of rare homozygous and compound heterozygous VPS13C missense mutations to dementia with Lewy bodies and Parkinson’s disease

B. Asselbergh, C. van Broeckhoven, S. Engelborghs, 2021, Acta Neuropathologica Communications.

Diagnostic value of cerebrospinal fluid tau, neurofilament, and progranulin in definite frontotemporal lobar degeneration

C. van Broeckhoven, S. Engelborghs, P. Cras, 2018 .

No added diagnostic value of non-phosphorylated tau fraction (p-taurel) in CSF as a biomarker for differential dementia diagnosis

H. Struyfs, C. van Broeckhoven, S. Engelborghs, 2017, Alzheimer's Research & Therapy.

Repetitive transcranial magnetic stimulation in patients with progressive supranuclear palsy: a pilot study.

P. Santens, M. De Letter, A. Sieben, 2009, Acta neurologica Belgica.

Brain Serotonergic and Noradrenergic Deficiencies in Behavioral Variant Frontotemporal Dementia Compared to Early-Onset Alzheimer's Disease.

Jean-Jacques Martin, A. Sieben, D. Van Dam, 2016, Journal of Alzheimer's disease : JAD.

Homozygous and compound heterozygous rare variants in VPS13C contribute to Lewy body diseases

P. Deyn, B. Asselbergh, S. Engelborghs, 2020 .

Contribution of homozygous and compound heterozygous missense mutations in VWA2 to Alzheimer’s disease

P. Deyn, B. Bergmans, C. Broeckhoven, 2020, Neurobiology of Aging.

Biomarker A+T−: is this Alzheimer’s disease or not? A combined CSF and pathology study

P. Visser, S. Engelborghs, F. Bouwman, 2022, Brain : a journal of neurology.

Validation of the Erlangen Score Algorithm for Differential Dementia Diagnosis in Autopsy-Confirmed Subjects

P. Lewczuk, C. van Broeckhoven, S. Engelborghs, 2019, Journal of Alzheimer's disease : JAD.

Bilingualism delays clinical manifestation of Alzheimer's

Michaël A. Stevens, W. Duyck, P. Santens, 2015 .

Therapy-Induced Electrophysiological Changes in Primary Progressive Aphasia: A Preliminary Study

W. Duyck, M. Miatton, P. van Mierlo, 2022, Frontiers in Human Neuroscience.

CSF proteome profiling reveals highly specific biomarkers for dementia with Lewy bodies.

J. David, S. Engelborghs, A. Lleó, 2023, medRxiv.

Saccadic Ping Pong Gaze in Coma

L. Crevits, P. Santens, A. Sieben, 2007, The neurologist.

Rare exonic variant affects GRN splicing and contributes to frontotemporal lobar degeneration

C. van Broeckhoven, A. Sieben, Helena Gossye, 2023, Neurobiology of Aging.

Mutated Toll-like receptor 9 increases Alzheimer's disease risk by compromising innate immunity protection.

C. van Broeckhoven, S. Engelborghs, R. Vandenberghe, 2023, Molecular psychiatry.

Corrigendum to “Deep brain stimulation of the internal pallidum in multiple system atrophy”

K. Vonck, P. Boon, D. Roost, 2007 .

CSF proteome profiling reveals biomarkers to discriminate dementia with Lewy bodies from Alzheimer´s disease

W. M. van der Flier, S. Engelborghs, A. Lleó, 2023, Nature communications.

Alzheimer’s disease and driving: review of the literature and consensus guideline from Belgian dementia experts and the Belgian road safety institute endorsed by the Belgian Medical Association

M. Ventura, S. Engelborghs, E. Salmon, 2017, Acta Neurologica Belgica.

This item is the archived peer-reviewed author-version of: Alzheimers disease and driving : review of the literature and consensus guideline from Belgian dementia experts and the Belgian road safety institute endorsed by the Belgian Medical Association Reference:

M. Ventura, S. Engelborghs, E. Salmon, 2017 .

Improved Alzheimer’s Disease versus Frontotemporal Lobar Degeneration Differential Diagnosis Combining EEG and Neurochemical Biomarkers: A Pilot Study

M. de Vos, C. van Broeckhoven, S. Engelborghs, 2022, Journal of Alzheimer's Disease.

Distinct clinical characteristics of C9orf72 expansion carriers compared with GRN, MAPT, and nonmutation carriers in a Flanders-Belgian FTLD cohort.

C. van Broeckhoven, S. Engelborghs, R. Vandenberghe, 2013, JAMA neurology.

Rare exonic variant affects GRN splicing and contributes to frontotemporal lobar degeneration

C. van Broeckhoven, A. Sieben, Helena Gossye, 2023, Neurobiology of Aging.

Running header : Bilingualism delays onset of Alzheimer ’ s disease Bilingualism delays clinical manifestation of Alzheimer ’ s disease *

W. Duyck, Evy Woumans, A. Sieben, 2014 .

Associating Alzheimer's disease pathology with its cerebrospinal fluid biomarkers.

H. Struyfs, C. van Broeckhoven, S. Engelborghs, 2022, Brain : a journal of neurology.