M. Blommers

发表

SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice.

Thomas M. Smith, D. Curtis, B. Tseng, 2015, Nature chemical biology.

Snags with tags : Some observations made with ( His ) 6-tagged proteins

S. Cowan-Jacob, M. Zurini, M. Blommers, 2002 .

Discovery of potent antagonists of the interaction between human double minute 2 and tumor suppressor p53.

P. Furet, C. García-echeverría, P. Chène, 2000, Journal of medicinal chemistry.

Library design for fragment based screening.

Edgar Jacoby, Ansgar Schuffenhauer, Wolfgang Jahnke, 2005, Current topics in medicinal chemistry.

Conformational analysis of a dinucleotide photodimer with the aid of the genetic algorithm

C. B. Lucasius, C. Lucasius, G. Kateman, 1992, Biopolymers.

Transferred Cross-Correlated Relaxation Complements Transferred NOE: Structure of an IL-4R-Derived Peptide Bound to STAT-6

W. Jahnke, M. Blommers, Carol E. Jones, 1999 .

Determination of aliphatic side-chain conformation using cross-correlated relaxation: application to an extraordinarily stable 2'-aminoethoxy-modified oligonucleotide triplex.

J. Meiler, C. Griesinger, B. Cuenoud, 2001, Journal of the American Chemical Society.

Derivation of dihedral angles from CH-CH dipolar-dipolar cross-correlated relaxation rates: a C-C torsion involving a quaternary carbon atom in epothilone A bound to tubulin.

C. Griesinger, T. Carlomagno, M. Blommers, 2003, Angewandte Chemie.

Strategies for the NMR‐Based Identification and Optimization of Allosteric Protein Kinase Inhibitors

W. Jahnke, C. Fernández, M. Blommers, 2005, Chembiochem : a European journal of chemical biology.

Exploring the Druggability of Conserved RNA Regulatory Elements in the SARS‐CoV‐2 Genome

H. Schwalbe, K. Azzaoui, U. Scheffer, 2021, Angewandte Chemie.

Exploring the Druggability of Conserved RNA Regulatory Elements in the SARS‐CoV‐2 Genome

H. Schwalbe, K. Azzaoui, U. Scheffer, 2021, Angewandte Chemie.

Lipid-protein nanodiscs as reference medium in detergent screening for high-resolution NMR studies of integral membrane proteins.

A. Arseniev, M. Kirpichnikov, V. Chupin, 2010, Journal of the American Chemical Society.

The three-dimensional structure of a DNA hairpin in solution two-dimensional NMR studies and structural analysis of d(ATCCTATTTATAGGAT).

C. W. Hilbers, G. A. van der Marel, M. Blommers, 1991, European journal of biochemistry.

Sequence-specific 1H and 15N assignment and secondary structure of transforming growth factor beta3.

A. Arseniev, T. Arvinte, E. Bocharov, 2000, Journal of biomolecular NMR.

NMR quality control of fragment libraries for screening

P. Schmieder, H. Schwalbe, K. Azzaoui, 2020, Journal of biomolecular NMR.

On the Interaction Between p53 and MDM2: Transfer NOE Study of a p53-Derived Peptide Ligated to MDM2

C. García-echeverría, P. Chène, G. Fendrich, 1997 .

Corrigendum: SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice.

Thomas M. Smith, John A. Tallarico, D. Curtis, 2015, Nature chemical biology.

Interaction of epothilone B (patupilone) with microtubules as detected by two-dimensional solid-state NMR spectroscopy.

E. Mandelkow, C. Griesinger, S. Jeganathan, 2010, Angewandte Chemie.

Design of small molecule libraries for NMR screening and other applications in drug discovery.

John Davies, Edgar Jacoby, Marcel J J Blommers, 2002, Current topics in medicinal chemistry.

A new class of HIV-1 Tat antagonist acting through Tat-TAR inhibition.

T. Klimkait, M. Blommers, A. Flörsheimer, 1998, Biochemistry.

Comparison of the Bioactive Conformations of Sialyl LewisX and a Potent Sialyl LewisX Mimic

W. Jahnke, B. Ernst, H. Kolb, 1997 .

Second-site NMR screening and linker design.

Wolfgang Jahnke, Marcel J J Blommers, Jutta Heim, 2003, Current topics in medicinal chemistry.

Dual recognition of double-stranded DNA by 2'-aminoethoxy-modified oligonucleotides: the solution structure of an intramolecular triplex obtained by NMR spectroscopy.

W. Jahnke, F. Natt, B. Cuenoud, 1998, Biochemistry.

Time efficient detection of protein–ligand interactions with the polarization optimized PO-WaterLOGSY NMR experiment

W. Jahnke, C. Fernández, M. Blommers, 2009, Journal of biomolecular NMR.

Modulation of the Bioactive Conformation of Transforming Growth Factor β: Possible Implications of Cation Binding for Biological Function.

A. Arseniev, K. Pavlov, T. Arvinte, 2008, Topics in current chemistry.

L-DNAs as potential antimessenger oligonucleotides: a reassessment.

C. Hilbers, L. Tondelli, M. Blommers, 1993, Nucleic acids research.

An approach to the structure determination of nucleic acid analogues hybridized to RNA. NMR studies of a duplex between 2'-OMe RNA and an oligonucleotide containing a single amide backbone modification.

M. Blommers, A. De Mesmaeker, U. Pieles, 1994, Nucleic acids research.

Molecular mechanics and dynamics studies on two structurally related amide-modified DNA backbones for antisense technology.

V. Fritsch, R. Wolf, M. Blommers, 1995, Bioorganic & medicinal chemistry.

Polypurine/polypyrimidine hairpins form a triple helix structure at low pH.

C. W. Hilbers, S. Wijmenga, M. Blommers, 1990, Nucleic acids research.

Creating RNA bulges: cleavage of RNA in RNA/DNA duplexes by metal ion catalysis.

W. Jahnke, G. Goodall, J. Hall, 1996, Biochemistry.

Solution structure of the 3'-5' cyclic dinucleotide d(pApA). A combined NMR, UV melting, and molecular mechanics study.

C. W. Hilbers, G. A. van der Marel, M. Blommers, 1988, Biochemistry.

Effects of the introduction of L-nucleotides into DNA. Solution structure of the heterochiral duplex d(G-C-G-(L)T-G-C-G).d(C-G-C-A-C-G-C) studied by NMR spectroscopy.

L. Tondelli, M. Blommers, A. Garbesi, 1994, Biochemistry.

Characterization of the Mechanism of Action of the Pan Class I PI3K Inhibitor NVP-BKM120 across a Broad Range of Concentrations

W. Sellers, A. Kauffmann, F. Hofmann, 2012, Molecular Cancer Therapeutics.

How to Computationally Stack the Deck for Hit-to-Lead Generation: In Silico Molecular Interaction Energy Profiling for de Novo siRNA Guide Strand Surrogate Selection

Marcel J J Blommers, Paulette A Greenidge, Jürg Hunziker, 2019, J. Chem. Inf. Model..

Crystal Structure of Human Estrogen-related Receptor α in Complex with a Synthetic Inverse Agonist Reveals Its Novel Molecular Mechanism*

M. Geiser, M. Blommers, B. Fournier, 2007, Journal of Biological Chemistry.

Comprehensive Fragment Screening of the SARS‐CoV‐2 Proteome Explores Novel Chemical Space for Drug Development

D. Laurents, J. Hoch, K. Saxena, 2022, Angewandte Chemie.

The Four Terminal Components of the Complement System AreC-Mannosylated on Multiple Tryptophan Residues*

J. Hofsteenge, D. Hess, M. Blommers, 1999, The Journal of Biological Chemistry.

Dynamics-modulated Biological Activity of Transforming Growth Factor β3* 210

M. Billeter, V. Orekhov, A. Arseniev, 2002, The Journal of Biological Chemistry.

Accretion of structure in staphylococcal nuclease: an 15N NMR relaxation study.

W. Jahnke, A. Alexandrescu, M. Blommers, 1996, Journal of molecular biology.

Heteronuclear NMR assignments and secondary structure of the coiled coil trimerization domain from cartilage matrix protein in oxidized and reduced forms

R. Kammerer, J. Engel, T. Schulthess, 1997, Protein science : a publication of the Protein Society.

The INPHARMA method: protein-mediated interligand NOEs for pharmacophore mapping.

Jens Meiler, Christian Griesinger, Marcel J J Blommers, 2005, Angewandte Chemie.

Conformational Analysis of DNA Using Genetic Algorithms

Gerrit Kateman, C. B. Lucasius, Carlos B. Lucasius, 1990, PPSN.

Optimisation of metric matrix embedding by genetic algorithms

C. B. Lucasius, L. M. C. Buydens, M. J. J. Blommers, 1996, Journal of biomolecular NMR.

NMR structural and dynamical investigation of the isolated voltage-sensing domain of the potassium channel KvAP: implications for voltage gating.

A. Arseniev, M. Kirpichnikov, V. Chupin, 2010, Journal of the American Chemical Society.

NMR Studies of Loopfolding in a DNA Hairpin Molecule

C. Hilbers, J. H. Boom, M. Blommers, 1987 .

NMR-Based Strategies to Elucidate Bioactive Conformations of Weakly Binding Ligands.

W. Jahnke, M. Geiser, M. Blommers, 2008, Topics in current chemistry.

The high-resolution solution structure of epothilone A bound to tubulin: an understanding of the structure-activity relationships for a powerful class of antitumor agents.

Jens Meiler, Christian Griesinger, Wolfgang Jahnke, 2003, Angewandte Chemie.

Structural basis of the activity of the microtubule-stabilizing agent epothilone a studied by NMR spectroscopy in solution.

Jens Meiler, Christian Griesinger, Marcel J J Blommers, 2007, Angewandte Chemie.

Synthetic and Semisynthetic Analogs of Epothilones: Chemistry and Biological Activity

K. Nicolaou, K. Altmann, G. Caravatti, 2001 .

Lipid-protein nanoscale bilayers: a versatile medium for NMR investigations of membrane proteins and membrane-active peptides.

A. Arseniev, M. Kirpichnikov, V. Chupin, 2008, Journal of the American Chemical Society.

Effects of base sequence on the loop folding in DNA hairpins.

C. W. Hilbers, G. A. van der Marel, C. Hilbers, 1989, Biochemistry.

Expression of G-protein coupled receptors in Escherichia coli for structural studies

O. Bocharova, A. Arseniev, Y. Ermolyuk, 2010, Biochemistry (Moscow).

Template‐Assembled Synthetic Proteins (TASP). Cyclic Templates with Incorporated Turn‐Inducing Mimics

M. Mutter, E. Francotte, M. Blommers, 1993 .

Conformational Aspects of Hairpin Loops in DNA Oligonucleotides

C. W. Hilbers, M. Blommers, C. Haasnoot, 1987 .

Conformational analysis of the 3'-5'-cyclic dinucleotide d less than pApA greater than by means of molecular mechanics.

C. W. Hilbers, G. A. van der Marel, M. Blommers, 1990, Journal of biomolecular structure & dynamics.

Recombinant human interleukin-12 is the second example of a C-mannosylated protein.

J. Hofsteenge, D. Hess, M. Blommers, 1999, Glycobiology.

Letter to the Editor: Sequence-specific 1H and 15N assignment and secondary structure of transforming growth factor β3

A. Arseniev, T. Arvinte, E. Bocharov, 2000 .

Biochemical and biophysical studies on the folding of the core region of the origin of replication of bacteriophage M13.

C. W. Hilbers, A. van Belkum, M. Blommers, 1990, Nucleic acids research.

Calculation of interproton distances from NOE intensities. A relaxation matrix approach without requirement of a molecular model

C. Hilbers, R. Schouten, M. Blommers, 1991 .

Aspects of the molecular structure and dynamics of neuropeptide Y.

A. Drake, H. Fretz, A. Nordmann, 1999, European journal of biochemistry.

SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice.

Thomas M. Smith, John A. Tallarico, D. Curtis, 2015, Nature chemical biology.

Lipid-protein nanodiscs as reference medium in detergent screening for high-resolution NMR studies of integral membrane proteins.

A. Arseniev, M. Kirpichnikov, V. Chupin, 2010, Journal of the American Chemical Society.

High Resolution NMR Studies of DNA Hairpins with Four Nucleotides in the Loop Region

J. H. Boom, M. Blommers, G. A. Marel, 1991 .

Determination of the backbone torsion angle ɛ in nucleic acids

D. Nanz, O. Zerbe, M. Blommers, 1994 .

Contributory presentations/posters

Diederichs, Bosco K. Ho, Hironori K. Nakamura, 1999, Journal of Biosciences.